ISMARA results: FOXA3

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXA3_FOXC2

Z-value: 3.42

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol	Gene ID	Gene Info
FOXA3 Ensembl NCBI GeneCards UniProt	ENSG00000170608.3	FOXA3
FOXC2 Ensembl NCBI GeneCards UniProt	ENSG00000176692.8	FOXC2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXC2	hg38_v1_chr16_+_86566821_86566836	-0.34	1.8e-07	Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr17_-_41528293 Show fit	13.87	ENST00000455635.1 ENST00000361566.7	KRT19 Ensembl NCBI GeneCards UniProt Show fit	keratin 19
chr5_+_136058849 Show fit	12.04	ENST00000508076.5	TGFBI Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta induced
chr18_+_3449620 Show fit	10.82	ENST00000405385.7	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr7_+_134891566 Show fit	9.53	ENST00000424922.5 ENST00000495522.1	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr8_+_96584920 Show fit	9.20	ENST00000521590.5	SDC2 Ensembl NCBI GeneCards UniProt Show fit	syndecan 2
chr11_-_116837586 Show fit	8.92	ENST00000375320.5 ENST00000359492.6 ENST00000375329.6 ENST00000375323.5 ENST00000236850.5	APOA1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein A1
chr17_-_28368012 Show fit	8.65	ENST00000555059.2	ENSG00000273171.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein, readthrough between VTN and SEBOX
chr7_+_112423137 Show fit	8.56	ENST00000005558.8 ENST00000621379.4	IFRD1 Ensembl NCBI GeneCards UniProt Show fit	interferon related developmental regulator 1
chr11_+_62419025 Show fit	8.40	ENST00000278282.3	SCGB1A1 Ensembl NCBI GeneCards UniProt Show fit	secretoglobin family 1A member 1
chr12_+_12891554 Show fit	8.33	ENST00000014914.6	GPRC5A Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor class C group 5 member A
chr2_-_105438503 Show fit	8.29	ENST00000393352.7 ENST00000607522.1	FHL2 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 2
chr7_+_134779625 Show fit	8.28	ENST00000454108.5 ENST00000361675.7	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr7_+_134779663 Show fit	8.25	ENST00000361901.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr11_+_126327863 Show fit	7.58	ENST00000648516.1	DCPS Ensembl NCBI GeneCards UniProt Show fit	decapping enzyme, scavenger
chr10_-_116273009 Show fit	7.45	ENST00000439649.8 ENST00000369234.5 ENST00000682194.1 ENST00000355422.11	GFRA1 Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 1
chr3_+_141387801 Show fit	7.11	ENST00000514251.5	ZBTB38 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr15_+_96325935 Show fit	7.02	ENST00000421109.6	NR2F2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 2
chr11_-_108593738 Show fit	6.99	ENST00000525344.5 ENST00000265843.9	EXPH5 Ensembl NCBI GeneCards UniProt Show fit	exophilin 5
chr7_-_108003122 Show fit	6.90	ENST00000393559.2 ENST00000222399.11 ENST00000676777.1 ENST00000439976.6 ENST00000393560.5 ENST00000677793.1 ENST00000679244.1	LAMB1 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 1
chr2_+_108607140 Show fit	6.72	ENST00000410093.5	LIMS1 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 1
chr10_-_125160499 Show fit	6.68	ENST00000494626.6 ENST00000337195.9	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr15_+_80072559 Show fit	6.34	ENST00000560228.5 ENST00000559835.5 ENST00000559775.5 ENST00000558688.5 ENST00000560392.5 ENST00000560976.5 ENST00000558272.5 ENST00000558390.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr10_+_69801892 Show fit	6.18	ENST00000398978.8 ENST00000645393.2 ENST00000354547.7 ENST00000674121.1 ENST00000673842.1 ENST00000520267.5	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr21_-_26843012 Show fit	6.05	ENST00000517777.6	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chrX_-_41589970 Show fit	5.98	ENST00000378179.9	CASK Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent serine protein kinase
chr3_+_172040554 Show fit	5.95	ENST00000336824.8 ENST00000423424.5	FNDC3B Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr21_-_26843063 Show fit	5.64	ENST00000678221.1	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr2_+_73892967 Show fit	5.62	ENST00000409731.7 ENST00000409918.5 ENST00000442912.5 ENST00000345517.8 ENST00000409624.1	ACTG2 Ensembl NCBI GeneCards UniProt Show fit	actin gamma 2, smooth muscle
chr8_-_63026179 Show fit	5.57	ENST00000677919.1	GGH Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl hydrolase
chr7_+_48924559 Show fit	5.56	ENST00000650262.1	CDC14C Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14C
chr18_-_28036585 Show fit	5.44	ENST00000399380.7	CDH2 Ensembl NCBI GeneCards UniProt Show fit	cadherin 2
chr10_-_125161019 Show fit	5.43	ENST00000411419.6	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr3_+_142596385 Show fit	5.29	ENST00000457734.7 ENST00000483373.5 ENST00000475296.5 ENST00000495744.5 ENST00000476044.5 ENST00000461644.5 ENST00000464320.5	PLS1 Ensembl NCBI GeneCards UniProt Show fit	plastin 1
chr5_+_96663010 Show fit	5.29	ENST00000506811.5 ENST00000514055.5 ENST00000508608.6	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr1_-_56966133 Show fit	5.23	ENST00000535057.5 ENST00000543257.5	C8B Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain
chr17_-_48610971 Show fit	5.17	ENST00000239165.9	HOXB7 Ensembl NCBI GeneCards UniProt Show fit	homeobox B7
chr6_+_52420992 Show fit	5.12	ENST00000636954.1 ENST00000636566.1 ENST00000638075.1	EFHC1 Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr10_+_122163672 Show fit	5.11	ENST00000369004.7 ENST00000260733.7	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr3_+_69936583 Show fit	5.01	ENST00000314557.10 ENST00000394351.9	MITF Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chr10_+_122163590 Show fit	5.00	ENST00000368999.5	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr5_-_138338325 Show fit	4.99	ENST00000510119.1 ENST00000513970.5	CDC25C Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25C
chr9_+_68241854 Show fit	4.91	ENST00000616550.4 ENST00000618217.4 ENST00000377342.9 ENST00000478048.5 ENST00000360171.11	CBWD3 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 3
chr14_-_24195334 Show fit	4.89	ENST00000530563.1 ENST00000528895.5 ENST00000528669.5 ENST00000532632.1 ENST00000261789.9	TM9SF1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 1
chr1_-_150697128 Show fit	4.89	ENST00000427665.1 ENST00000271732.8	GOLPH3L Ensembl NCBI GeneCards UniProt Show fit	golgi phosphoprotein 3 like
chr9_-_41189310 Show fit	4.76	ENST00000456520.5 ENST00000377391.8 ENST00000613716.4 ENST00000617933.1	CBWD6 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 6
chr15_-_58749569 Show fit	4.71	ENST00000402627.5 ENST00000559053.1 ENST00000260408.8 ENST00000561288.1 ENST00000461408.2 ENST00000439637.5 ENST00000558004.1	ADAM10 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 10
chr5_+_32531786 Show fit	4.71	ENST00000512913.5	SUB1 Ensembl NCBI GeneCards UniProt Show fit	SUB1 regulator of transcription
chr4_+_146175702 Show fit	4.59	ENST00000296581.11 ENST00000649747.1 ENST00000502781.5	LSM6 Ensembl NCBI GeneCards UniProt Show fit	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_-_139302460 Show fit	4.57	ENST00000394223.2 ENST00000676245.1	NDUFC1 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit C1
chr4_-_139302516 Show fit	4.55	ENST00000394228.5 ENST00000539387.5	NDUFC1 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit C1
chr6_+_36676489 Show fit	4.49	ENST00000448526.6	CDKN1A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr5_+_96662969 Show fit	4.36	ENST00000514845.5 ENST00000675663.1	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chrX_-_20218941 Show fit	4.31	ENST00000457145.6	RPS6KA3 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr18_+_49562049 Show fit	4.28	ENST00000261292.9 ENST00000427224.6 ENST00000580036.5	LIPG Ensembl NCBI GeneCards UniProt Show fit	lipase G, endothelial type
chr11_-_11353241 Show fit	4.12	ENST00000528848.3	CSNK2A3 Ensembl NCBI GeneCards UniProt Show fit	casein kinase 2 alpha 3
chr2_+_113437691 Show fit	4.06	ENST00000259199.9 ENST00000416503.6 ENST00000433343.6	CBWD2 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 2
chrX_-_41665766 Show fit	4.03	ENST00000643043.2 ENST00000486402.1 ENST00000646087.2	CASK Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent serine protein kinase
chr17_-_19387170 Show fit	4.00	ENST00000395592.6 ENST00000299610.5	MFAP4 Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 4
chr3_-_108222383 Show fit	3.98	ENST00000264538.4	IFT57 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 57
chr14_+_55661272 Show fit	3.97	ENST00000555573.5	KTN1 Ensembl NCBI GeneCards UniProt Show fit	kinectin 1
chr3_-_134250831 Show fit	3.91	ENST00000623711.4	RYK Ensembl NCBI GeneCards UniProt Show fit	receptor like tyrosine kinase
chr11_+_102112445 Show fit	3.87	ENST00000524575.5	YAP1 Ensembl NCBI GeneCards UniProt Show fit	Yes1 associated transcriptional regulator
chr7_+_134891400 Show fit	3.79	ENST00000393118.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr11_+_20363685 Show fit	3.73	ENST00000530266.5 ENST00000451739.7 ENST00000421577.6 ENST00000443524.6 ENST00000419348.6	HTATIP2 Ensembl NCBI GeneCards UniProt Show fit	HIV-1 Tat interactive protein 2
chr6_-_41747390 Show fit	3.70	ENST00000356667.8 ENST00000373025.7 ENST00000425343.6	PGC Ensembl NCBI GeneCards UniProt Show fit	progastricsin
chr4_-_71784046 Show fit	3.69	ENST00000513476.5 ENST00000273951.13	GC Ensembl NCBI GeneCards UniProt Show fit	GC vitamin D binding protein
chr1_-_56966006 Show fit	3.68	ENST00000371237.9	C8B Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain
chr4_+_73404255 Show fit	3.62	ENST00000621628.4 ENST00000621085.4 ENST00000415165.6 ENST00000295897.9 ENST00000503124.5 ENST00000509063.5 ENST00000401494.7	ALB Ensembl NCBI GeneCards UniProt Show fit	albumin
chr20_+_9069076 Show fit	3.60	ENST00000378473.9	PLCB4 Ensembl NCBI GeneCards UniProt Show fit	phospholipase C beta 4
chr11_-_66345066 Show fit	3.58	ENST00000359957.8 ENST00000425825.6	BRMS1 Ensembl NCBI GeneCards UniProt Show fit	BRMS1 transcriptional repressor and anoikis regulator
chr8_-_23404076 Show fit	3.52	ENST00000524168.1 ENST00000389131.8 ENST00000523833.2 ENST00000519243.1	LOXL2 Ensembl NCBI GeneCards UniProt Show fit	lysyl oxidase like 2
chr14_+_51240205 Show fit	3.44	ENST00000457354.7	TMX1 Ensembl NCBI GeneCards UniProt Show fit	thioredoxin related transmembrane protein 1
chr3_+_130850585 Show fit	3.41	ENST00000505330.5 ENST00000504381.5 ENST00000507488.6	ATP2C1 Ensembl NCBI GeneCards UniProt Show fit	ATPase secretory pathway Ca2+ transporting 1
chr10_+_113709261 Show fit	3.40	ENST00000672138.1 ENST00000452490.3	CASP7 Ensembl NCBI GeneCards UniProt Show fit	caspase 7
chr7_+_134745460 Show fit	3.36	ENST00000436461.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr2_-_224569782 Show fit	3.34	ENST00000409096.5	CUL3 Ensembl NCBI GeneCards UniProt Show fit	cullin 3
chr6_+_125203639 Show fit	3.32	ENST00000392482.6	TPD52L1 Ensembl NCBI GeneCards UniProt Show fit	TPD52 like 1
chr17_-_28370283 Show fit	3.26	ENST00000226218.9	VTN Ensembl NCBI GeneCards UniProt Show fit	vitronectin
chr3_-_197183963 Show fit	3.22	ENST00000653795.1	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr1_+_74235377 Show fit	3.20	ENST00000326637.8	TNNI3K Ensembl NCBI GeneCards UniProt Show fit	TNNI3 interacting kinase
chr4_-_185535498 Show fit	3.18	ENST00000284767.12 ENST00000284771.7 ENST00000284770.10 ENST00000620787.5 ENST00000629667.2	PDLIM3 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 3
chr7_+_77840122 Show fit	3.17	ENST00000450574.5 ENST00000248550.7	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr1_-_246566238 Show fit	3.13	ENST00000366514.5	TFB2M Ensembl NCBI GeneCards UniProt Show fit	transcription factor B2, mitochondrial
chr17_+_7583828 Show fit	3.13	ENST00000396501.8 ENST00000250124.11 ENST00000584378.5 ENST00000423172.6 ENST00000579445.5 ENST00000585217.5 ENST00000581380.1	MPDU1 Ensembl NCBI GeneCards UniProt Show fit	mannose-P-dolichol utilization defect 1
chr14_+_20688756 Show fit	3.06	ENST00000397990.5 ENST00000555597.1	ANG Ensembl NCBI GeneCards UniProt Show fit RNASE4 Ensembl NCBI GeneCards UniProt Show fit	angiogenin ribonuclease A family member 4
chr2_+_180981108 Show fit	3.05	ENST00000602710.5	UBE2E3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 E3
chr17_+_42998379 Show fit	3.01	ENST00000253788.12 ENST00000589913.6	RPL27 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L27
chr3_-_197183806 Show fit	3.00	ENST00000671246.1 ENST00000660553.1	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr1_-_53940100 Show fit	3.00	ENST00000371376.1	HSPB11 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr10_-_116273606 Show fit	2.96	ENST00000682743.1	GFRA1 Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 1
chr7_+_73828160 Show fit	2.89	ENST00000431918.1	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr8_+_31639755 Show fit	2.86	ENST00000520407.5	NRG1 Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chr10_+_69801874 Show fit	2.86	ENST00000357811.8	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr1_-_244860376 Show fit	2.85	ENST00000638716.1	HNRNPU Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein U
chr12_+_103930600 Show fit	2.85	ENST00000680316.1 ENST00000679861.1	HSP90B1 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein 90 beta family member 1
chr2_+_28395511 Show fit	2.83	ENST00000436647.1	FOSL2 Ensembl NCBI GeneCards UniProt Show fit	FOS like 2, AP-1 transcription factor subunit
chr8_+_11809135 Show fit	2.80	ENST00000528643.5 ENST00000525777.5	FDFT1 Ensembl NCBI GeneCards UniProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chr21_-_37072688 Show fit	2.75	ENST00000464265.5 ENST00000399102.5	PIGP Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class P
chr9_-_72953047 Show fit	2.64	ENST00000297785.8 ENST00000376939.5	ALDH1A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A1
chr17_+_7572818 Show fit	2.61	ENST00000293831.13 ENST00000582169.5 ENST00000578754.5 ENST00000578495.5 ENST00000585024.5 ENST00000583802.5 ENST00000577269.5 ENST00000584784.5 ENST00000582746.5 ENST00000581621.1	EIF4A1 Ensembl NCBI GeneCards UniProt Show fit ENSG00000264772.6 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4A1 novel transcript
chr12_-_47705971 Show fit	2.54	ENST00000380650.4	RPAP3 Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II associated protein 3
chr22_+_20774092 Show fit	2.52	ENST00000215727.10	SERPIND1 Ensembl NCBI GeneCards UniProt Show fit	serpin family D member 1
chr4_+_145482761 Show fit	2.52	ENST00000507367.1 ENST00000394092.6 ENST00000515385.1	SMAD1 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 1
chr15_-_29822418 Show fit	2.50	ENST00000614355.5 ENST00000495972.6 ENST00000346128.10	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr3_-_100114488 Show fit	2.43	ENST00000477258.2 ENST00000354552.7 ENST00000331335.9 ENST00000398326.2	FILIP1L Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1 like
chr3_+_136930469 Show fit	2.43	ENST00000469404.1 ENST00000467911.1	NCK1 Ensembl NCBI GeneCards UniProt Show fit	NCK adaptor protein 1
chr7_+_28412511 Show fit	2.42	ENST00000357727.7	CREB5 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 5
chr7_+_95485898 Show fit	2.37	ENST00000428113.5	ASB4 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 4
chr10_+_122163426 Show fit	2.37	ENST00000360561.7	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr3_-_114179052 Show fit	2.33	ENST00000383673.5 ENST00000295881.9	DRD3 Ensembl NCBI GeneCards UniProt Show fit	dopamine receptor D3
chr19_+_40751179 Show fit	2.32	ENST00000243563.8 ENST00000601393.1	SNRPA Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr6_-_87095059 Show fit	2.31	ENST00000369582.6 ENST00000610310.3 ENST00000630630.2 ENST00000627148.3 ENST00000625577.1	CGA Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormones, alpha polypeptide
chr10_+_69802424 Show fit	2.30	ENST00000673802.2 ENST00000517713.5 ENST00000520133.5 ENST00000522165.5 ENST00000673641.2 ENST00000673628.2	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr12_-_47705990 Show fit	2.27	ENST00000432584.7 ENST00000005386.8	RPAP3 Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II associated protein 3
chr1_-_246193727 Show fit	2.26	ENST00000391836.3	SMYD3 Ensembl NCBI GeneCards UniProt Show fit	SET and MYND domain containing 3
chr10_+_122560751 Show fit	2.19	ENST00000338354.10 ENST00000664692.1 ENST00000653442.1 ENST00000664974.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr1_+_152514474 Show fit	2.17	ENST00000368790.4	CRCT1 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich C-terminal 1
chr9_+_65675834 Show fit	2.14	ENST00000377392.9 ENST00000377384.5 ENST00000430059.6 ENST00000429800.6 ENST00000382405.8 ENST00000377395.8	CBWD5 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 5
chr3_-_197183849 Show fit	2.08	ENST00000443183.5	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr20_+_11917859 Show fit	2.05	ENST00000618296.4 ENST00000378226.7	BTBD3 Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 3
chr2_-_21044063 Show fit	2.04	ENST00000233242.5	APOB Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B
chr20_+_33235987 Show fit	2.03	ENST00000375422.6 ENST00000375413.8 ENST00000354297.9	BPIFA1 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family A member 1
chr10_+_122560679 Show fit	1.98	ENST00000657942.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr20_+_37744630 Show fit	1.96	ENST00000373473.5	CTNNBL1 Ensembl NCBI GeneCards UniProt Show fit	catenin beta like 1
chr10_+_122560639 Show fit	1.96	ENST00000344338.7 ENST00000330163.8 ENST00000652446.2 ENST00000666315.1 ENST00000368955.7 ENST00000368909.7 ENST00000368956.6 ENST00000619379.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr8_-_94436926 Show fit	1.94	ENST00000481490.3	FSBP Ensembl NCBI GeneCards UniProt Show fit	fibrinogen silencer binding protein
chr2_-_86195400 Show fit	1.92	ENST00000442664.6 ENST00000409051.6 ENST00000410111.8 ENST00000620815.4 ENST00000449247.6	IMMT Ensembl NCBI GeneCards UniProt Show fit	inner membrane mitochondrial protein
chr17_+_74431338 Show fit	1.90	ENST00000342648.9 ENST00000652232.1 ENST00000481232.2	GPRC5C Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor class C group 5 member C
chr4_+_168092530 Show fit	1.89	ENST00000359299.8	ANXA10 Ensembl NCBI GeneCards UniProt Show fit	annexin A10
chr3_+_137998735 Show fit	1.88	ENST00000343735.8	CLDN18 Ensembl NCBI GeneCards UniProt Show fit	claudin 18
chr1_+_23691742 Show fit	1.88	ENST00000374550.8 ENST00000643754.2	RPL11 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L11
chr8_-_80080816 Show fit	1.82	ENST00000520527.5 ENST00000517427.5 ENST00000379097.7 ENST00000448733.3	TPD52 Ensembl NCBI GeneCards UniProt Show fit	tumor protein D52
chr12_+_21372899 Show fit	1.82	ENST00000240652.8 ENST00000542023.1 ENST00000537593.1	IAPP Ensembl NCBI GeneCards UniProt Show fit	islet amyloid polypeptide
chr17_+_76376581 Show fit	1.80	ENST00000591651.5 ENST00000545180.5	SPHK1 Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr7_+_117014881 Show fit	1.72	ENST00000422922.5 ENST00000432298.5	ST7 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 7
chr1_+_207104226 Show fit	1.72	ENST00000367070.8	C4BPA Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein alpha
chr22_-_21227637 Show fit	1.69	ENST00000401924.5	GGT2 Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyltransferase 2
chr3_+_69936629 Show fit	1.69	ENST00000394348.2 ENST00000531774.1	MITF Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chr4_-_102345469 Show fit	1.69	ENST00000356736.5 ENST00000682932.1	SLC39A8 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 8
chr6_+_5260992 Show fit	1.64	ENST00000324331.10	FARS2 Ensembl NCBI GeneCards UniProt Show fit	phenylalanyl-tRNA synthetase 2, mitochondrial
chr3_+_14178808 Show fit	1.63	ENST00000306024.4	LSM3 Ensembl NCBI GeneCards UniProt Show fit	LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr15_+_49170200 Show fit	1.63	ENST00000396509.6	GALK2 Ensembl NCBI GeneCards UniProt Show fit	galactokinase 2
chr7_+_130266847 Show fit	1.62	ENST00000222481.9	CPA2 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A2
chr1_-_167553745 Show fit	1.60	ENST00000370509.5	CREG1 Ensembl NCBI GeneCards UniProt Show fit	cellular repressor of E1A stimulated genes 1
chr20_-_7940444 Show fit	1.58	ENST00000378789.4	HAO1 Ensembl NCBI GeneCards UniProt Show fit	hydroxyacid oxidase 1
chr14_-_25010604 Show fit	1.56	ENST00000550887.5	STXBP6 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 6
chr11_-_6440980 Show fit	1.50	ENST00000265983.8 ENST00000615166.1	HPX Ensembl NCBI GeneCards UniProt Show fit	hemopexin
chr5_+_138338256 Show fit	1.50	ENST00000513056.5 ENST00000239906.10 ENST00000511276.1	FAM53C Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 53 member C
chr4_-_185775271 Show fit	1.47	ENST00000430503.5 ENST00000319454.10 ENST00000450341.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr2_-_46617020 Show fit	1.45	ENST00000474980.1 ENST00000281382.11 ENST00000306465.8	PIGF Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class F
chr8_+_19313685 Show fit	1.44	ENST00000265807.8 ENST00000518040.5	SH2D4A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 4A
chr1_-_169586471 Show fit	1.43	ENST00000367797.9	F5 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor V
chr14_+_20343607 Show fit	1.42	ENST00000250416.9 ENST00000429687.8 ENST00000527915.5	PARP2 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase 2
chr17_+_9021501 Show fit	1.42	ENST00000173229.7	NTN1 Ensembl NCBI GeneCards UniProt Show fit	netrin 1
chr9_-_92424427 Show fit	1.42	ENST00000375550.5	OMD Ensembl NCBI GeneCards UniProt Show fit	osteomodulin
chr10_+_103555124 Show fit	1.40	ENST00000437579.1	NEURL1 Ensembl NCBI GeneCards UniProt Show fit	neuralized E3 ubiquitin protein ligase 1
chr15_-_59372863 Show fit	1.39	ENST00000288235.9	MYO1E Ensembl NCBI GeneCards UniProt Show fit	myosin IE
chr5_+_143812161 Show fit	1.36	ENST00000289448.4	HMHB1 Ensembl NCBI GeneCards UniProt Show fit	histocompatibility minor HB-1
chr11_-_115504389 Show fit	1.34	ENST00000545380.5 ENST00000452722.7 ENST00000331581.11 ENST00000537058.5 ENST00000536727.5 ENST00000542447.6	CADM1 Ensembl NCBI GeneCards UniProt Show fit	cell adhesion molecule 1
chr4_-_69495897 Show fit	1.34	ENST00000305107.7 ENST00000639621.1	UGT2B4 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B4
chrX_-_134658450 Show fit	1.33	ENST00000359237.9	PLAC1 Ensembl NCBI GeneCards UniProt Show fit	placenta enriched 1
chr21_-_42366525 Show fit	1.31	ENST00000291527.3	TFF1 Ensembl NCBI GeneCards UniProt Show fit	trefoil factor 1
chr3_+_155870623 Show fit	1.28	ENST00000295920.7 ENST00000496455.7	GMPS Ensembl NCBI GeneCards UniProt Show fit	guanine monophosphate synthase
chr3_+_136022734 Show fit	1.28	ENST00000334546.6	PPP2R3A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B''alpha
chr4_-_69495861 Show fit	1.22	ENST00000512583.5	UGT2B4 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B4
chr4_-_122456725 Show fit	1.22	ENST00000226730.5	IL2 Ensembl NCBI GeneCards UniProt Show fit	interleukin 2
chr15_-_66504832 Show fit	1.19	ENST00000569438.2 ENST00000569696.5 ENST00000307961.11	RPL4 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L4
chr9_-_107489754 Show fit	1.17	ENST00000610832.1 ENST00000374672.5	KLF4 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 4
chr12_+_57694118 Show fit	1.16	ENST00000315970.12 ENST00000547079.5 ENST00000439210.6 ENST00000389146.10 ENST00000413095.6 ENST00000551035.5 ENST00000257966.12 ENST00000435406.6 ENST00000550372.5 ENST00000389142.9	OS9 Ensembl NCBI GeneCards UniProt Show fit	OS9 endoplasmic reticulum lectin
chr6_+_10528326 Show fit	1.15	ENST00000379597.7	GCNT2 Ensembl NCBI GeneCards UniProt Show fit	glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr1_-_43389768 Show fit	1.14	ENST00000372455.4 ENST00000372457.9 ENST00000290663.10	MED8 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 8
chrX_+_136532205 Show fit	1.12	ENST00000370634.8	VGLL1 Ensembl NCBI GeneCards UniProt Show fit	vestigial like family member 1
chr10_+_35195124 Show fit	1.12	ENST00000487763.5 ENST00000473940.5 ENST00000488328.5 ENST00000356917.9	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr5_-_41213505 Show fit	1.10	ENST00000337836.10 ENST00000433294.1	C6 Ensembl NCBI GeneCards UniProt Show fit	complement C6
chr17_-_352784 Show fit	1.09	ENST00000577079.5 ENST00000331302.12 ENST00000618002.4 ENST00000536489.6	RPH3AL Ensembl NCBI GeneCards UniProt Show fit	rabphilin 3A like (without C2 domains)
chr6_-_112254647 Show fit	1.06	ENST00000455073.1 ENST00000522006.5 ENST00000519932.5	LAMA4 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 4
chr6_-_25830557 Show fit	1.06	ENST00000468082.1	SLC17A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 1
chr15_+_49170237 Show fit	1.02	ENST00000560031.6 ENST00000558145.5 ENST00000544523.5 ENST00000560138.5	GALK2 Ensembl NCBI GeneCards UniProt Show fit	galactokinase 2
chr3_+_138010143 Show fit	1.01	ENST00000183605.10	CLDN18 Ensembl NCBI GeneCards UniProt Show fit	claudin 18
chr15_+_75043263 Show fit	1.01	ENST00000563393.1	PPCDC Ensembl NCBI GeneCards UniProt Show fit	phosphopantothenoylcysteine decarboxylase
chr5_+_148394712 Show fit	1.00	ENST00000513826.1	FBXO38 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 38
chr3_+_159852933 Show fit	0.98	ENST00000482804.1	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr12_-_102478539 Show fit	0.97	ENST00000424202.6	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr13_+_52024691 Show fit	0.97	ENST00000521776.2	UTP14C Ensembl NCBI GeneCards UniProt Show fit	UTP14C small subunit processome component
chr4_-_169757873 Show fit	0.94	ENST00000393381.3	HPF1 Ensembl NCBI GeneCards UniProt Show fit	histone PARylation factor 1
chr12_-_14885845 Show fit	0.93	ENST00000539261.6 ENST00000228938.5	MGP Ensembl NCBI GeneCards UniProt Show fit	matrix Gla protein
chr4_-_115113614 Show fit	0.91	ENST00000264363.7	NDST4 Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase and N-sulfotransferase 4
chr6_-_24666591 Show fit	0.91	ENST00000341060.3	TDP2 Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-DNA phosphodiesterase 2
chr12_-_71157872 Show fit	0.89	ENST00000546561.2	TSPAN8 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 8
chr13_-_74133892 Show fit	0.89	ENST00000377669.7	KLF12 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 12
chr1_-_28058087 Show fit	0.89	ENST00000373864.5	EYA3 Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 3
chr1_+_179882275 Show fit	0.88	ENST00000606911.7 ENST00000271583.7	TOR1AIP1 Ensembl NCBI GeneCards UniProt Show fit	torsin 1A interacting protein 1
chr3_+_148730100 Show fit	0.88	ENST00000474935.5 ENST00000475347.5 ENST00000461609.1	AGTR1 Ensembl NCBI GeneCards UniProt Show fit	angiotensin II receptor type 1
chr7_-_25228485 Show fit	0.86	ENST00000222674.2	NPVF Ensembl NCBI GeneCards UniProt Show fit	neuropeptide VF precursor
chr6_+_26251607 Show fit	0.85	ENST00000619466.2	H2BC9 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 9
chr19_-_45584769 Show fit	0.84	ENST00000263275.5	OPA3 Ensembl NCBI GeneCards UniProt Show fit	outer mitochondrial membrane lipid metabolism regulator OPA3
chr19_+_926001 Show fit	0.84	ENST00000263620.8	ARID3A Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 3A
chr1_-_169586539 Show fit	0.83	ENST00000367796.3	F5 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor V
chr9_-_14722725 Show fit	0.83	ENST00000380911.4	CER1 Ensembl NCBI GeneCards UniProt Show fit	cerberus 1, DAN family BMP antagonist
chr18_-_3874247 Show fit	0.82	ENST00000581699.5	DLGAP1 Ensembl NCBI GeneCards UniProt Show fit	DLG associated protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	8.6	GO:0007518	myoblast fate determination(GO:0007518)
2.5	7.6	GO:0036245	cellular response to menadione(GO:0036245)
2.1	4.3	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
2.1	8.3	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
2.0	11.7	GO:0008218	bioluminescence(GO:0008218)
1.8	8.9	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.8	7.0	GO:0009956	radial pattern formation(GO:0009956)
1.7	8.4	GO:0010193	response to ozone(GO:0010193)
1.4	5.6	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.2	12.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.2	3.6	GO:0019836	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.2	4.7	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.2	1.2	GO:0014740	negative regulation of muscle hyperplasia(GO:0014740)
1.1	5.6	GO:0090131	mesenchyme migration(GO:0090131)
1.1	3.3	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
1.1	5.3	GO:1902896	terminal web assembly(GO:1902896)
1.0	3.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
1.0	3.9	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.9	10.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.9	2.6	GO:0006711	estrogen catabolic process(GO:0006711)
0.8	2.4	GO:1903676	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.8	2.4	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.7	6.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.6	11.5	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.6	10.0	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.6	3.7	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.6	1.8	GO:0046521	sphingoid catabolic process(GO:0046521)
0.6	8.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.6	2.3	GO:0032416	negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.6	3.4	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.6	6.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.6	8.3	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.5	3.1	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.5	2.0	GO:0044407	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.5	1.5	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5	2.5	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.5	4.5	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.5	1.9	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.5	2.8	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.4	3.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.4	8.9	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.4	4.9	GO:0048194	Golgi vesicle budding(GO:0048194)
0.4	2.6	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4	3.4	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.4	9.6	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.4	7.0	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.4	3.6	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.4	2.8	GO:0002051	osteoblast fate commitment(GO:0002051)
0.4	13.9	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.4	2.3	GO:0032571	response to vitamin K(GO:0032571)
0.4	1.1	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4	3.3	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.4	2.9	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.3	5.6	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.3	1.7	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.3	2.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.3	1.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.3	4.0	GO:0048251	elastic fiber assembly(GO:0048251)
0.3	1.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3	2.6	GO:0009441	glycolate metabolic process(GO:0009441)
0.3	0.9	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.3	7.0	GO:0060972	left/right pattern formation(GO:0060972)
0.3	0.8	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3	0.8	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.3	1.3	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	1.2	GO:2000320	regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2	2.9	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2	1.4	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.2	11.4	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2	2.8	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.2	6.3	GO:0072663	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2	4.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.2	0.8	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.2	2.9	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	0.4	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2	1.4	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2	5.2	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2	1.4	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.2	11.3	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2	1.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	1.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.2	1.7	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.2	1.8	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	6.7	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.2	1.7	GO:0071763	nuclear membrane organization(GO:0071763)
0.2	2.0	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.2	1.3	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.2	12.0	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.2	3.2	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.2	6.2	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2	3.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2	1.6	GO:0051601	exocyst localization(GO:0051601)
0.2	3.5	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.2	1.4	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.1	4.3	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.1	1.9	GO:0042407	cristae formation(GO:0042407)
0.1	3.7	GO:0042359	vitamin D metabolic process(GO:0042359)
0.1	5.0	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1	14.5	GO:0021987	cerebral cortex development(GO:0021987)
0.1	1.2	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	0.6	GO:0071918	canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.1	12.1	GO:0002062	chondrocyte differentiation(GO:0002062)
0.1	9.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.5	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	2.7	GO:0006012	galactose metabolic process(GO:0006012)
0.1	1.7	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	0.9	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	0.7	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	1.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.4	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	2.9	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	2.3	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.1	1.0	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	1.6	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	0.7	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.1	1.1	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.1	0.9	GO:0001502	cartilage condensation(GO:0001502)
0.1	0.9	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	3.3	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	0.6	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1	2.8	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.1	2.3	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.1	2.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	1.5	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.3	GO:0019532	oxalate transport(GO:0019532)
0.0	2.3	GO:0016486	peptide hormone processing(GO:0016486)
0.0	1.3	GO:0035902	response to immobilization stress(GO:0035902)
0.0	1.0	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.6	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	3.4	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.8	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.1	GO:1903568	negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0	0.1	GO:0015847	putrescine transport(GO:0015847)
0.0	0.8	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	14.8	GO:0006936	muscle contraction(GO:0006936)
0.0	4.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.0	0.1	GO:0072537	fibroblast activation(GO:0072537)
0.0	0.3	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.5	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.5	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	3.6	GO:0007018	microtubule-based movement(GO:0007018)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	1.1	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.8	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.0	3.7	GO:0051170	nuclear import(GO:0051170)
0.0	0.6	GO:0006611	protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	11.3	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
3.2	19.2	GO:1990357	terminal web(GO:1990357)
2.3	6.9	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
2.2	8.9	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
2.2	33.2	GO:0030478	actin cap(GO:0030478)
1.3	3.9	GO:0071148	TEAD-1-YAP complex(GO:0071148)
1.3	10.0	GO:0005579	membrane attack complex(GO:0005579)
1.1	3.3	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.9	4.5	GO:0070557	PCNA-p21 complex(GO:0070557)
0.8	12.1	GO:0097470	ribbon synapse(GO:0097470)
0.5	3.1	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.5	4.8	GO:0097255	R2TP complex(GO:0097255)
0.5	6.2	GO:0005688	U6 snRNP(GO:0005688)
0.5	10.0	GO:0005652	nuclear lamina(GO:0005652)
0.5	4.7	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.4	4.0	GO:0071953	elastic fiber(GO:0071953)
0.4	3.3	GO:0005827	polar microtubule(GO:0005827)
0.4	8.3	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.4	2.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.4	5.6	GO:0042589	zymogen granule membrane(GO:0042589)
0.3	1.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3	4.0	GO:0044292	dendrite terminus(GO:0044292)
0.3	1.9	GO:0061617	MICOS complex(GO:0061617)
0.3	30.9	GO:0005604	basement membrane(GO:0005604)
0.3	2.8	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3	5.4	GO:0016342	catenin complex(GO:0016342)
0.3	2.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2	1.2	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2	5.6	GO:0032982	myosin filament(GO:0032982)
0.2	2.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	0.7	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.2	2.9	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	8.3	GO:0031430	M band(GO:0031430)
0.2	1.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2	1.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	3.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	3.6	GO:0070822	Sin3-type complex(GO:0070822)
0.1	2.6	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	2.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	9.1	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	4.9	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.8	GO:0044279	extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1	2.8	GO:0071141	SMAD protein complex(GO:0071141)
0.1	3.6	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	13.0	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.5	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	8.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	10.7	GO:0072686	mitotic spindle(GO:0072686)
0.1	2.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.6	GO:0000145	exocyst(GO:0000145)
0.1	2.3	GO:0005685	U1 snRNP(GO:0005685)
0.1	2.5	GO:0005921	gap junction(GO:0005921)
0.1	1.4	GO:0097440	apical dendrite(GO:0097440)
0.1	2.9	GO:0030673	axolemma(GO:0030673)
0.1	10.4	GO:0031225	anchored component of membrane(GO:0031225)
0.1	1.1	GO:0000974	Prp19 complex(GO:0000974)
0.1	13.4	GO:0072562	blood microparticle(GO:0072562)
0.1	5.6	GO:0035580	specific granule lumen(GO:0035580)
0.1	3.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	4.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	7.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	4.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	1.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	2.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	1.6	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.3	GO:0097225	sperm midpiece(GO:0097225)
0.0	1.0	GO:0032040	small-subunit processome(GO:0032040)
0.0	1.1	GO:0016592	mediator complex(GO:0016592)
0.0	1.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.9	GO:0016235	aggresome(GO:0016235)
0.0	4.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	3.3	GO:0030018	Z disc(GO:0030018)
0.0	12.9	GO:0005815	microtubule organizing center(GO:0005815)
0.0	1.4	GO:0016459	myosin complex(GO:0016459)
0.0	2.1	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.8	GO:0043198	dendritic shaft(GO:0043198)
0.0	4.7	GO:0005635	nuclear envelope(GO:0005635)
0.0	1.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	3.5	GO:0005769	early endosome(GO:0005769)
0.0	9.3	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	13.9	GO:0005783	endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.1	GO:0035375	zymogen binding(GO:0035375)
1.8	8.9	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
1.7	12.1	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.7	8.4	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.5	10.4	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.2	3.7	GO:1902271	D3 vitamins binding(GO:1902271)
1.2	31.9	GO:0005523	tropomyosin binding(GO:0005523)
1.2	3.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
1.1	3.3	GO:0031208	POZ domain binding(GO:0031208)
1.0	9.6	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.9	4.5	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.9	2.7	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.8	7.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.6	3.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.6	4.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.6	10.0	GO:0042043	neurexin family protein binding(GO:0042043)
0.6	3.9	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.5	3.2	GO:0031013	troponin I binding(GO:0031013)
0.5	1.6	GO:0003973	(S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.5	3.1	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5	2.0	GO:0035473	lipase binding(GO:0035473)
0.5	1.4	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.5	2.8	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5	2.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.5	8.3	GO:0097016	L27 domain binding(GO:0097016)
0.4	13.3	GO:0070410	co-SMAD binding(GO:0070410)
0.4	2.6	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4	2.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3	7.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.3	2.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.3	7.3	GO:0008242	omega peptidase activity(GO:0008242)
0.3	1.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	2.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3	0.9	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3	0.9	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.3	5.4	GO:0045294	alpha-catenin binding(GO:0045294)
0.3	1.8	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3	9.6	GO:0001972	retinoic acid binding(GO:0001972)
0.2	1.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.2	3.6	GO:0015643	toxic substance binding(GO:0015643)
0.2	1.2	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2	2.3	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2	4.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2	2.8	GO:0046790	virion binding(GO:0046790)
0.2	0.6	GO:0015265	urea channel activity(GO:0015265)
0.2	1.5	GO:0015232	heme transporter activity(GO:0015232)
0.2	1.9	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2	2.6	GO:0000339	RNA cap binding(GO:0000339)
0.2	1.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.2	1.4	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.2	15.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	17.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	9.1	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2	1.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2	2.9	GO:0005176	ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	3.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1	1.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.8	GO:0016015	morphogen activity(GO:0016015)
0.1	1.1	GO:0030274	LIM domain binding(GO:0030274)
0.1	23.8	GO:0008201	heparin binding(GO:0008201)
0.1	8.3	GO:0050681	androgen receptor binding(GO:0050681)
0.1	1.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	3.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	3.9	GO:0070064	proline-rich region binding(GO:0070064)
0.1	10.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	6.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.4	GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1	1.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	4.7	GO:0050699	WW domain binding(GO:0050699)
0.1	0.8	GO:1990405	protein antigen binding(GO:1990405)
0.1	5.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	0.6	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	2.9	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	4.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	3.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	2.3	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	1.3	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	1.6	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	1.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	11.7	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.1	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	1.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	4.0	GO:0019894	kinesin binding(GO:0019894)
0.1	7.2	GO:0030165	PDZ domain binding(GO:0030165)
0.1	1.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	0.3	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	3.1	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	1.7	GO:0005521	lamin binding(GO:0005521)
0.1	6.7	GO:0005178	integrin binding(GO:0005178)
0.0	0.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	1.9	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0003963	RNA-3'-phosphate cyclase activity(GO:0003963)
0.0	1.4	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.9	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	5.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0015203	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0	0.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	1.1	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	1.8	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	8.5	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	10.8	GO:0045296	cadherin binding(GO:0045296)
0.0	1.4	GO:0045182	translation regulator activity(GO:0045182)
0.0	1.0	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.7	GO:0019956	chemokine binding(GO:0019956)
0.0	0.9	GO:0005507	copper ion binding(GO:0005507)
0.0	0.3	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.0	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.0	0.9	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	25.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	21.9	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	12.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.3	20.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.3	19.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	12.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	9.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	3.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	10.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.2	12.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	4.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	2.8	PID ALK2 PATHWAY	ALK2 signaling events
0.1	7.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	3.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	2.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	12.1	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	5.0	PID ATM PATHWAY	ATM pathway
0.1	6.7	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	10.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	5.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	6.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	3.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	3.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	2.9	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	0.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	19.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	1.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	2.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	1.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	2.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.9	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	6.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	37.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	7.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5	12.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.4	4.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3	9.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.3	6.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3	13.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.3	5.0	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.3	2.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	11.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.2	6.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	10.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2	10.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	7.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	4.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.2	6.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	2.8	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	2.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	2.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	4.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2	11.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	6.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	2.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	4.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	5.8	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	3.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	3.7	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	1.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	2.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	9.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	2.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.1	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.1	2.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	4.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	1.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	10.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	3.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	11.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	2.6	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.1	5.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	3.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.6	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	6.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	3.1	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	5.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters

Results for FOXA3_FOXC2

Z-value: 3.42

Motif logo

Transcription factors associated with FOXA3_FOXC2

Activity-expression correlation:

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: