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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXF2_FOXJ1

Z-value: 2.09

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Transcription factors associated with FOXF2_FOXJ1

Gene Symbol Gene ID Gene Info
FOXF2
ENSG00000137273.6 FOXF2
FOXJ1
ENSG00000129654.8 FOXJ1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ1hg38_v1_chr17_-_76141240_761412670.351.7e-07Click!
FOXF2hg38_v1_chr6_+_1389553_13896050.127.1e-02Click!

Activity profile of FOXF2_FOXJ1 motif

Sorted Z-values of FOXF2_FOXJ1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_21025490 22.22 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG2
NDRG family member 2
chr14_-_21025000 21.10 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG2
NDRG family member 2
chr5_-_42811884 17.13 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
SELENOP
selenoprotein P
chr20_+_45406560 15.49 ENST00000372717.5
ENST00000360981.8
DBNDD2
dysbindin domain containing 2
chr20_+_45407207 14.46 ENST00000372712.6
DBNDD2
dysbindin domain containing 2
chr1_+_92080305 9.99 ENST00000342818.4
ENST00000636805.2
BTBD8
BTB domain containing 8
chr17_+_74431338 9.40 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
GPRC5C
G protein-coupled receptor class C group 5 member C
chr16_+_56191476 8.83 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr19_-_36032799 8.35 ENST00000592017.5
ENST00000360535.9
CLIP3
CAP-Gly domain containing linker protein 3
chr10_+_122163590 7.82 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chr14_-_100569780 7.80 ENST00000355173.7
BEGAIN
brain enriched guanylate kinase associated
chr15_-_34337462 7.69 ENST00000676379.1
SLC12A6
solute carrier family 12 member 6
chr8_-_133297092 7.39 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
NDRG1
N-myc downstream regulated 1
chr16_+_6019585 7.08 ENST00000547372.5
RBFOX1
RNA binding fox-1 homolog 1
chr2_-_36966471 7.02 ENST00000379213.3
STRN
striatin
chr2_+_232662733 6.82 ENST00000410095.5
ENST00000611312.1
EFHD1
EF-hand domain family member D1
chr10_+_122163672 6.77 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr10_+_122163426 6.73 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chr11_+_114060204 6.70 ENST00000683318.1
ZBTB16
zinc finger and BTB domain containing 16
chr5_-_131796921 6.67 ENST00000307968.11
ENST00000307954.12
FNIP1
folliculin interacting protein 1
chr1_-_56966006 6.65 ENST00000371237.9
C8B
complement C8 beta chain
chr1_-_161223408 6.64 ENST00000491350.1
APOA2
apolipoprotein A2
chr15_-_34318761 6.29 ENST00000290209.9
SLC12A6
solute carrier family 12 member 6
chr11_-_114595777 6.23 ENST00000375478.4
NXPE4
neurexophilin and PC-esterase domain family member 4
chr11_-_114595750 6.17 ENST00000424261.6
NXPE4
neurexophilin and PC-esterase domain family member 4
chr14_-_74084393 6.06 ENST00000350259.8
ENST00000553458.6
ALDH6A1
aldehyde dehydrogenase 6 family member A1
chr14_-_103521342 5.93 ENST00000553610.5
CKB
creatine kinase B
chr16_+_6019016 5.87 ENST00000550418.6
RBFOX1
RNA binding fox-1 homolog 1
chr5_-_131797030 5.69 ENST00000615660.4
FNIP1
folliculin interacting protein 1
chr1_+_65264694 5.58 ENST00000263441.11
ENST00000395325.7
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6
chr16_+_6019071 5.44 ENST00000547605.5
ENST00000553186.5
RBFOX1
RNA binding fox-1 homolog 1
chr2_+_33436304 5.27 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr3_+_124384513 5.25 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
KALRN
kalirin RhoGEF kinase
chr1_-_161223559 5.22 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
APOA2
apolipoprotein A2
chr1_-_56966133 4.74 ENST00000535057.5
ENST00000543257.5
C8B
complement C8 beta chain
chr11_-_115504389 4.52 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr11_+_1157946 4.51 ENST00000621226.2
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr3_-_10505508 4.31 ENST00000643662.1
ENST00000397077.6
ENST00000360273.7
ATP2B2
ATPase plasma membrane Ca2+ transporting 2
chrX_+_71215156 4.27 ENST00000374029.2
ENST00000675209.1
ENST00000647424.1
ENST00000675368.1
ENST00000675609.1
ENST00000646835.1
ENST00000447581.2
GJB1
gap junction protein beta 1
chr15_-_72686176 4.27 ENST00000311755.6
HIGD2B
HIG1 hypoxia inducible domain family member 2B
chr5_-_142686079 4.26 ENST00000337706.7
FGF1
fibroblast growth factor 1
chr11_+_72080313 4.25 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
ENSG00000284922.2
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr19_-_58098203 4.24 ENST00000600845.1
ENST00000240727.10
ENST00000600897.5
ENST00000421612.6
ENST00000601063.1
ENST00000601144.6
ZSCAN18
zinc finger and SCAN domain containing 18
chr14_+_22829879 4.11 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr22_-_37109409 4.00 ENST00000406725.6
TMPRSS6
transmembrane serine protease 6
chr2_+_127418420 3.98 ENST00000234071.8
ENST00000429925.5
ENST00000442644.5
PROC
protein C, inactivator of coagulation factors Va and VIIIa
chrX_+_57592011 3.93 ENST00000374888.3
ZXDB
zinc finger X-linked duplicated B
chr16_+_84145256 3.81 ENST00000378553.10
DNAAF1
dynein axonemal assembly factor 1
chr15_-_34337719 3.78 ENST00000559484.1
ENST00000558589.5
ENST00000458406.6
SLC12A6
solute carrier family 12 member 6
chr15_-_34338033 3.74 ENST00000558667.5
ENST00000561120.5
ENST00000559236.5
ENST00000397702.6
SLC12A6
solute carrier family 12 member 6
chr15_-_34337772 3.56 ENST00000354181.8
SLC12A6
solute carrier family 12 member 6
chrX_-_57910458 3.43 ENST00000358697.6
ZXDA
zinc finger X-linked duplicated A
chr19_+_18386150 3.39 ENST00000252809.3
GDF15
growth differentiation factor 15
chr19_+_41262656 3.30 ENST00000599719.5
ENST00000601309.5
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U like 1
chr11_+_70398404 3.30 ENST00000346329.7
ENST00000301843.13
ENST00000376561.7
CTTN
cortactin
chr1_+_50105666 3.23 ENST00000651347.1
ELAVL4
ELAV like RNA binding protein 4
chr6_+_101398788 3.12 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr11_-_5505604 3.11 ENST00000380237.5
ENST00000292896.3
ENST00000380252.6
HBE1
HBG2
hemoglobin subunit epsilon 1
hemoglobin subunit gamma 2
chr6_-_56843153 3.08 ENST00000361203.7
ENST00000523817.1
DST
dystonin
chr14_+_74084947 3.07 ENST00000674221.1
ENST00000554938.2
LIN52
lin-52 DREAM MuvB core complex component
chr4_-_89836213 3.05 ENST00000618500.4
ENST00000508895.5
SNCA
synuclein alpha
chr2_-_36966503 3.03 ENST00000263918.9
STRN
striatin
chr15_+_42404842 2.99 ENST00000673928.1
CAPN3
calpain 3
chr10_-_121596117 2.96 ENST00000351936.11
FGFR2
fibroblast growth factor receptor 2
chr12_+_93677352 2.93 ENST00000552983.5
ENST00000332896.8
ENST00000552033.5
ENST00000548483.5
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr12_+_49741544 2.89 ENST00000549966.5
ENST00000547832.5
ENST00000547187.5
ENST00000548894.5
ENST00000546914.5
ENST00000552699.5
ENST00000267115.10
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr11_+_108665122 2.85 ENST00000526794.1
DDX10
DEAD-box helicase 10
chr12_-_71157872 2.84 ENST00000546561.2
TSPAN8
tetraspanin 8
chr1_+_220528333 2.77 ENST00000677505.1
MARK1
microtubule affinity regulating kinase 1
chrX_-_108736556 2.68 ENST00000372129.4
IRS4
insulin receptor substrate 4
chr15_+_42404820 2.63 ENST00000673839.1
ENST00000673978.1
CAPN3
calpain 3
chr5_+_141417659 2.57 ENST00000398594.4
PCDHGB7
protocadherin gamma subfamily B, 7
chr10_+_110225955 2.53 ENST00000239007.11
MXI1
MAX interactor 1, dimerization protein
chr15_+_42404866 2.49 ENST00000674041.1
ENST00000565559.5
ENST00000673750.1
ENST00000674135.1
CAPN3
calpain 3
chr4_+_70721953 2.46 ENST00000381006.8
ENST00000226328.8
RUFY3
RUN and FYVE domain containing 3
chr22_-_37109703 2.41 ENST00000406856.7
ENST00000676104.1
TMPRSS6
transmembrane serine protease 6
chr20_+_33235987 2.37 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr6_+_32154131 2.36 ENST00000375143.6
ENST00000324816.11
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr13_+_87671354 2.30 ENST00000683689.1
SLITRK5
SLIT and NTRK like family member 5
chr17_+_69414690 2.30 ENST00000590474.7
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_+_28335718 2.28 ENST00000226225.7
TNFAIP1
TNF alpha induced protein 1
chr12_-_62935117 2.21 ENST00000228705.7
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr3_-_58537181 2.19 ENST00000302819.10
ACOX2
acyl-CoA oxidase 2
chr12_+_49741565 2.19 ENST00000549445.5
ENST00000550951.5
ENST00000549385.5
ENST00000548713.5
ENST00000548201.5
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr3_-_38816217 2.18 ENST00000449082.3
ENST00000655275.1
SCN10A
sodium voltage-gated channel alpha subunit 10
chr3_-_58537283 2.16 ENST00000459701.6
ACOX2
acyl-CoA oxidase 2
chr2_+_219178266 2.12 ENST00000430297.7
RETREG2
reticulophagy regulator family member 2
chr17_+_79778135 2.11 ENST00000310942.9
ENST00000269399.5
CBX2
chromobox 2
chr11_+_27055215 2.10 ENST00000525090.1
BBOX1
gamma-butyrobetaine hydroxylase 1
chr19_+_49877660 2.10 ENST00000535102.6
TBC1D17
TBC1 domain family member 17
chr6_+_160702238 2.08 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
PLG
plasminogen
chr19_+_49877425 2.06 ENST00000622860.4
TBC1D17
TBC1 domain family member 17
chr14_-_94323324 2.02 ENST00000341584.4
SERPINA6
serpin family A member 6
chr6_+_72212802 2.00 ENST00000401910.7
RIMS1
regulating synaptic membrane exocytosis 1
chr8_+_31639291 1.98 ENST00000651149.1
ENST00000650866.1
NRG1
neuregulin 1
chr4_+_159241016 1.96 ENST00000644902.1
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr17_-_7179348 1.96 ENST00000573083.1
ENST00000574388.5
ENST00000269299.8
ASGR1
asialoglycoprotein receptor 1
chr1_+_226940279 1.95 ENST00000366778.5
ENST00000366777.4
COQ8A
coenzyme Q8A
chr18_+_57352541 1.94 ENST00000324000.4
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr3_-_186109067 1.92 ENST00000306376.10
ETV5
ETS variant transcription factor 5
chr4_-_69961007 1.91 ENST00000353151.3
CSN2
casein beta
chr9_-_74887720 1.87 ENST00000449912.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr6_+_32154010 1.84 ENST00000375137.6
PPT2
palmitoyl-protein thioesterase 2
chr4_+_99574812 1.81 ENST00000422897.6
ENST00000265517.10
MTTP
microsomal triglyceride transfer protein
chr3_+_119579676 1.80 ENST00000357003.7
ADPRH
ADP-ribosylarginine hydrolase
chr5_-_19988179 1.80 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
CDH18
cadherin 18
chr9_-_74887914 1.80 ENST00000360774.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr15_+_72686197 1.77 ENST00000268057.9
ENST00000569338.5
BBS4
Bardet-Biedl syndrome 4
chr2_+_174395721 1.76 ENST00000272732.11
ENST00000458563.5
ENST00000409673.7
ENST00000435964.1
ENST00000424069.5
ENST00000427038.5
SCRN3
secernin 3
chr18_+_34493386 1.75 ENST00000679936.1
DTNA
dystrobrevin alpha
chr7_-_17940468 1.75 ENST00000611725.4
ENST00000409604.1
ENST00000428135.7
SNX13
sorting nexin 13
chr19_+_49877694 1.74 ENST00000221543.10
TBC1D17
TBC1 domain family member 17
chr17_-_41786688 1.73 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
JUP
junction plakoglobin
chr6_+_72212887 1.73 ENST00000523963.5
RIMS1
regulating synaptic membrane exocytosis 1
chr17_+_28335571 1.72 ENST00000544907.6
TNFAIP1
TNF alpha induced protein 1
chr4_-_81471855 1.71 ENST00000436139.6
ENST00000613784.1
RASGEF1B
RasGEF domain family member 1B
chr19_-_52028347 1.67 ENST00000356322.10
ENST00000270649.11
ZNF614
zinc finger protein 614
chr6_-_56851888 1.61 ENST00000312431.10
ENST00000520645.5
DST
dystonin
chr7_-_140924699 1.60 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr20_-_22585451 1.54 ENST00000377115.4
FOXA2
forkhead box A2
chr1_+_220528112 1.52 ENST00000366917.6
ENST00000402574.5
ENST00000611084.4
ENST00000366918.8
MARK1
microtubule affinity regulating kinase 1
chr4_-_69495861 1.51 ENST00000512583.5
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr15_+_72686179 1.49 ENST00000395205.6
BBS4
Bardet-Biedl syndrome 4
chr4_+_87832917 1.46 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr4_-_69495897 1.41 ENST00000305107.7
ENST00000639621.1
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr4_-_89835617 1.39 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
SNCA
synuclein alpha
chr2_-_165953750 1.39 ENST00000243344.8
ENST00000679799.1
ENST00000679840.1
ENST00000681606.1
ENST00000680448.1
TTC21B
tetratricopeptide repeat domain 21B
chr14_+_49768109 1.36 ENST00000298307.10
ENST00000554589.5
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr4_+_70242583 1.36 ENST00000304954.3
CSN3
casein kappa
chr15_-_58279245 1.36 ENST00000558231.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr17_+_60677822 1.31 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3
BCAS3 microtubule associated cell migration factor
chr9_-_132944600 1.31 ENST00000490179.3
ENST00000643583.1
ENST00000298552.9
ENST00000643072.1
ENST00000642745.1
ENST00000647462.1
ENST00000643875.1
ENST00000642627.1
ENST00000475903.6
ENST00000642617.1
ENST00000642646.1
ENST00000646625.1
ENST00000645150.1
ENST00000645129.1
ENST00000403810.6
ENST00000643691.1
ENST00000644097.1
TSC1
TSC complex subunit 1
chr11_-_64166102 1.30 ENST00000255681.7
ENST00000675777.1
MACROD1
mono-ADP ribosylhydrolase 1
chr19_+_49527988 1.30 ENST00000270645.8
RCN3
reticulocalbin 3
chr12_+_47773195 1.27 ENST00000442218.3
SLC48A1
solute carrier family 48 member 1
chr3_+_119579577 1.26 ENST00000478927.5
ADPRH
ADP-ribosylarginine hydrolase
chr6_-_160258814 1.24 ENST00000366953.8
SLC22A2
solute carrier family 22 member 2
chr2_-_219178103 1.20 ENST00000409789.5
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr18_-_54959391 1.19 ENST00000591504.6
CCDC68
coiled-coil domain containing 68
chr14_-_70809494 1.17 ENST00000381250.8
ENST00000554752.7
ENST00000555993.6
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr7_+_44606578 1.13 ENST00000443864.6
ENST00000447398.5
ENST00000449767.5
ENST00000419661.5
OGDH
oxoglutarate dehydrogenase
chr7_+_116953238 1.13 ENST00000393446.6
ST7
suppression of tumorigenicity 7
chrY_-_23694579 1.12 ENST00000343584.10
PRYP3
PTPN13 like Y-linked pseudogene 3
chr8_+_38386303 1.11 ENST00000519476.6
LETM2
leucine zipper and EF-hand containing transmembrane protein 2
chr20_-_46364385 1.10 ENST00000243896.6
ENST00000543605.5
ENST00000372230.10
ENST00000317734.12
SLC35C2
solute carrier family 35 member C2
chr4_-_69760610 1.08 ENST00000310613.8
SULT1B1
sulfotransferase family 1B member 1
chr2_-_171894227 1.08 ENST00000422440.7
SLC25A12
solute carrier family 25 member 12
chr12_-_102197827 1.07 ENST00000329406.5
PMCH
pro-melanin concentrating hormone
chr12_-_71157992 1.06 ENST00000247829.8
TSPAN8
tetraspanin 8
chr6_+_29457155 1.02 ENST00000377133.6
ENST00000377136.5
OR2H1
olfactory receptor family 2 subfamily H member 1
chr8_-_71547626 0.99 ENST00000647540.1
ENST00000644229.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr8_+_31639222 0.99 ENST00000519301.6
ENST00000652698.1
NRG1
neuregulin 1
chr2_-_27356975 0.98 ENST00000423998.1
ENST00000264720.7
GTF3C2
general transcription factor IIIC subunit 2
chr2_-_164773733 0.95 ENST00000480873.1
COBLL1
cordon-bleu WH2 repeat protein like 1
chr1_+_207496147 0.92 ENST00000400960.7
ENST00000367049.9
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr19_-_18791297 0.92 ENST00000542601.6
ENST00000222271.7
ENST00000425807.1
COMP
cartilage oligomeric matrix protein
chr13_-_102401599 0.90 ENST00000376131.8
FGF14
fibroblast growth factor 14
chr9_+_117704382 0.90 ENST00000646089.1
ENST00000355622.8
ENSG00000285082.2
TLR4
novel protein
toll like receptor 4
chr9_+_117704168 0.89 ENST00000472304.2
ENST00000394487.5
TLR4
toll like receptor 4
chr12_-_21775581 0.88 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr1_+_207496229 0.85 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr9_-_5185628 0.81 ENST00000381641.4
ENST00000649639.1
INSL6
insulin like 6
chr6_-_160664270 0.81 ENST00000316300.10
LPA
lipoprotein(a)
chr15_-_30991415 0.79 ENST00000563714.5
MTMR10
myotubularin related protein 10
chr3_+_137998735 0.78 ENST00000343735.8
CLDN18
claudin 18
chr3_+_98732236 0.78 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr5_+_141199555 0.78 ENST00000624887.1
ENST00000354757.5
PCDHB11
protocadherin beta 11
chr1_-_24143112 0.76 ENST00000270800.2
IL22RA1
interleukin 22 receptor subunit alpha 1
chr16_+_77199408 0.75 ENST00000378644.5
SYCE1L
synaptonemal complex central element protein 1 like
chrX_+_9912434 0.73 ENST00000418909.6
SHROOM2
shroom family member 2
chrX_+_49162564 0.73 ENST00000616266.4
MAGIX
MAGI family member, X-linked
chr7_+_1088106 0.72 ENST00000397088.4
GPER1
G protein-coupled estrogen receptor 1
chr3_+_171843337 0.68 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr1_-_168137430 0.67 ENST00000546300.5
ENST00000271357.9
ENST00000367835.1
ENST00000537209.5
GPR161
G protein-coupled receptor 161
chr8_-_6563409 0.66 ENST00000325203.9
ANGPT2
angiopoietin 2
chr6_+_99521027 0.66 ENST00000452647.3
ENST00000636394.1
TSTD3
thiosulfate sulfurtransferase like domain containing 3
chr3_+_159852933 0.64 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr6_+_112054075 0.64 ENST00000230529.9
ENST00000604763.5
ENST00000368666.7
ENST00000674325.1
ENST00000483439.1
ENST00000409166.5
CCN6
cellular communication network factor 6
chr3_+_189631373 0.64 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
TP63
tumor protein p63
chr21_-_18403754 0.63 ENST00000284885.8
TMPRSS15
transmembrane serine protease 15
chr12_-_52949818 0.63 ENST00000546897.5
ENST00000552551.5
KRT8
keratin 8
chr9_+_137665916 0.62 ENST00000636027.1
EHMT1
euchromatic histone lysine methyltransferase 1
chr4_-_185535498 0.62 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDLIM3
PDZ and LIM domain 3
chr2_+_73892967 0.61 ENST00000409731.7
ENST00000409918.5
ENST00000442912.5
ENST00000345517.8
ENST00000409624.1
ACTG2
actin gamma 2, smooth muscle
chr1_-_93847150 0.60 ENST00000370244.5
BCAR3
BCAR3 adaptor protein, NSP family member
chr7_+_73828160 0.60 ENST00000431918.1
CLDN4
claudin 4
chr6_-_112254485 0.59 ENST00000521398.5
ENST00000424408.6
ENST00000243219.7
LAMA4
laminin subunit alpha 4
chr3_+_48918815 0.57 ENST00000452882.5
ENST00000430423.5
ENST00000449376.5
ENST00000356401.9
ENST00000420814.5
ENST00000449729.5
ENST00000433170.5
ARIH2
ariadne RBR E3 ubiquitin protein ligase 2
chr2_+_87748087 0.56 ENST00000359481.9
PLGLB2
plasminogen like B2
chr1_+_43389889 0.55 ENST00000562955.2
ENST00000634258.3
SZT2
SZT2 subunit of KICSTOR complex
chr7_+_135148041 0.55 ENST00000275767.3
TMEM140
transmembrane protein 140
chr7_-_140924900 0.54 ENST00000646891.1
ENST00000644969.2
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr12_-_55958582 0.47 ENST00000549404.5
PMEL
premelanosome protein
chr1_-_152115443 0.46 ENST00000614923.1
TCHH
trichohyalin
chr1_-_150010675 0.46 ENST00000417191.2
ENST00000581312.6
OTUD7B
OTU deubiquitinase 7B
chr5_+_150661243 0.44 ENST00000517768.6
MYOZ3
myozenin 3
chr12_-_95996302 0.43 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr3_+_52211442 0.43 ENST00000459884.1
ALAS1
5'-aminolevulinate synthase 1
chr11_-_46593948 0.42 ENST00000533727.5
ENST00000534300.5
ENST00000683756.1
ENST00000528950.1
ENST00000526606.1
AMBRA1
autophagy and beclin 1 regulator 1
chr6_+_113857333 0.42 ENST00000612661.2
MARCKS
myristoylated alanine rich protein kinase C substrate

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 25.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
3.0 11.9 GO:0060620 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
2.5 43.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.3 11.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
2.1 17.1 GO:0001887 selenium compound metabolic process(GO:0001887)
2.1 8.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
2.0 6.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.3 4.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
1.2 8.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.0 5.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.0 2.9 GO:0006711 estrogen catabolic process(GO:0006711)
0.9 8.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.9 4.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.8 5.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.8 7.1 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.8 2.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.7 4.4 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.7 6.4 GO:0097264 self proteolysis(GO:0097264)
0.7 2.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.7 2.0 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.7 7.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.7 12.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 4.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.6 1.9 GO:1903487 regulation of lactation(GO:1903487)
0.6 4.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.6 1.8 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.6 2.4 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.6 5.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.6 1.7 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.5 1.5 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.5 3.0 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.5 5.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 2.0 GO:2000670 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.4 4.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 4.3 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.4 4.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.4 1.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 2.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 0.9 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.3 2.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.3 GO:0051029 rRNA transport(GO:0051029)
0.3 3.5 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.2 18.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 0.7 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
0.2 0.7 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 4.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 4.2 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.2 3.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 1.8 GO:0034378 chylomicron assembly(GO:0034378)
0.2 2.2 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.2 1.4 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 1.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.7 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 0.6 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.2 8.8 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.2 2.3 GO:0021756 striatum development(GO:0021756)
0.2 3.1 GO:0015671 oxygen transport(GO:0015671)
0.2 0.6 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.2 1.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.3 GO:0015886 heme transport(GO:0015886)
0.1 1.0 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 1.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.1 20.9 GO:0021987 cerebral cortex development(GO:0021987)
0.1 4.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 3.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.9 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.8 GO:0097503 sialylation(GO:0097503)
0.1 10.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 1.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 3.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 1.2 GO:1901374 acetate ester transport(GO:1901374)
0.1 0.3 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.6 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 2.5 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.7 GO:0045176 apical protein localization(GO:0045176)
0.1 1.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 3.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 22.8 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 5.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.5 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.6 GO:0060992 response to fungicide(GO:0060992)
0.1 2.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.6 GO:0061436 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 2.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 3.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.9 GO:0051923 ethanol catabolic process(GO:0006068) sulfation(GO:0051923)
0.0 1.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.8 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 2.9 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 4.6 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.5 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 4.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 7.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.4 GO:0007595 lactation(GO:0007595)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.4 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664) negative regulation of cardiac muscle cell apoptotic process(GO:0010667) response to mitochondrial depolarisation(GO:0098780)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0070701 mucus layer(GO:0070701)
1.4 11.4 GO:0005579 membrane attack complex(GO:0005579)
1.0 3.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.9 4.7 GO:0031673 H zone(GO:0031673)
0.9 17.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 11.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 3.3 GO:0034464 BBSome(GO:0034464)
0.4 5.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 2.1 GO:0044279 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 1.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 29.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 2.2 GO:0071439 clathrin complex(GO:0071439)
0.3 10.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 4.3 GO:0005922 connexon complex(GO:0005922)
0.2 53.5 GO:0030426 growth cone(GO:0030426)
0.2 16.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 3.1 GO:0005833 hemoglobin complex(GO:0005833)
0.2 1.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 1.7 GO:0005915 zonula adherens(GO:0005915)
0.1 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.0 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 8.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 8.1 GO:0030315 T-tubule(GO:0030315)
0.1 6.9 GO:0055037 recycling endosome(GO:0055037)
0.1 3.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 4.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 29.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 4.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 18.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 3.7 GO:0031526 brush border membrane(GO:0031526)
0.1 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 3.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 6.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 6.4 GO:0043209 myelin sheath(GO:0043209)
0.0 3.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 6.6 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.4 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.7 GO:0030496 midbody(GO:0030496)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.9 GO:0042383 sarcolemma(GO:0042383)
0.0 6.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 12.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 5.0 GO:0043235 receptor complex(GO:0043235)
0.0 10.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.6 GO:0005903 brush border(GO:0005903)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.4 11.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.1 8.3 GO:0097001 ceramide binding(GO:0097001)
1.8 25.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.4 17.1 GO:0008430 selenium binding(GO:0008430)
0.8 3.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.7 5.9 GO:0004111 creatine kinase activity(GO:0004111)
0.7 4.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.7 4.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.7 5.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.7 2.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.7 2.0 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.6 8.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.5 5.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 8.1 GO:0031432 titin binding(GO:0031432)
0.5 4.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.4 3.1 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 10.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 4.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 1.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 7.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 1.2 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 1.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 6.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 4.3 GO:0005243 gap junction channel activity(GO:0005243)
0.3 2.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.3 1.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 0.8 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.3 2.1 GO:1990405 protein antigen binding(GO:1990405)
0.2 3.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 1.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 7.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.3 GO:0034452 dynactin binding(GO:0034452)
0.2 4.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 4.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 0.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 4.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 3.3 GO:0005522 profilin binding(GO:0005522)
0.2 4.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 5.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 4.3 GO:0044548 S100 protein binding(GO:0044548)
0.2 2.9 GO:0070513 death domain binding(GO:0070513)
0.2 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 3.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 4.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 21.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 2.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.4 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 2.9 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 17.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 6.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 3.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.1 5.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 11.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 5.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 2.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.8 GO:0043531 ADP binding(GO:0043531)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 3.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0036122 morphogen activity(GO:0016015) BMP binding(GO:0036122)
0.0 1.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 48.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 8.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 5.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 3.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 8.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 7.6 PID FGF PATHWAY FGF signaling pathway
0.1 4.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 7.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 13.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 5.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 8.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 6.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 8.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 24.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 5.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 4.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 3.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 3.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 5.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.8 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 6.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 2.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction