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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for FOXK1_FOXP2_FOXB1_FOXP3
Z-value: 8.02
Motif logo
Transcription factors associated with FOXK1_FOXP2_FOXB1_FOXP3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FOXK1
|
ENSG00000164916.11 | FOXK1 |
|
FOXP2
|
ENSG00000128573.26 | FOXP2 |
|
FOXB1
|
ENSG00000171956.7 | FOXB1 |
|
FOXP3
|
ENSG00000049768.17 | FOXP3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXK1 | hg38_v1_chr7_+_4682252_4682314 | 0.65 | 2.2e-27 | Click! |
| FOXP3 | hg38_v1_chrX_-_49264668_49264800 | 0.45 | 2.0e-12 | Click! |
| FOXB1 | hg38_v1_chr15_+_60004305_60004319 | 0.24 | 3.6e-04 | Click! |
Activity profile of FOXK1_FOXP2_FOXB1_FOXP3 motif
Sorted Z-values of FOXK1_FOXP2_FOXB1_FOXP3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXK1_FOXP2_FOXB1_FOXP3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 25.6 | 76.7 | GO:0001868 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 14.4 | 72.0 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 12.7 | 215.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 9.8 | 78.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 9.7 | 67.7 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 9.7 | 125.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 9.1 | 45.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 8.8 | 26.3 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 8.5 | 144.4 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 7.5 | 44.9 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 7.4 | 44.2 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 6.4 | 19.3 | GO:0045957 | regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957) |
| 6.2 | 37.4 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 5.7 | 68.8 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 5.6 | 16.9 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 5.5 | 27.7 | GO:0030070 | insulin processing(GO:0030070) |
| 5.3 | 26.5 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 4.9 | 19.7 | GO:0010157 | response to chlorate(GO:0010157) |
| 4.8 | 14.5 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 4.7 | 14.2 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 4.3 | 43.2 | GO:0036309 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 4.3 | 12.9 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 4.2 | 33.6 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 4.2 | 25.0 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 4.1 | 20.5 | GO:0044858 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 4.1 | 12.3 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 4.1 | 20.4 | GO:1990164 | histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164) |
| 3.8 | 15.4 | GO:0046113 | nucleobase catabolic process(GO:0046113) |
| 3.8 | 7.6 | GO:0044179 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 3.6 | 18.0 | GO:1904209 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 3.5 | 17.6 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 3.4 | 13.7 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 3.4 | 23.8 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 3.3 | 3.3 | GO:0042704 | uterine wall breakdown(GO:0042704) |
| 3.2 | 16.1 | GO:0051029 | rRNA transport(GO:0051029) |
| 3.2 | 57.2 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 3.1 | 12.5 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 3.1 | 24.8 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 3.1 | 24.8 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 3.1 | 3.1 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 3.0 | 14.8 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 2.9 | 23.5 | GO:0061709 | reticulophagy(GO:0061709) |
| 2.9 | 14.6 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 2.8 | 5.7 | GO:1902263 | apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 2.8 | 19.3 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 2.7 | 24.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 2.7 | 16.4 | GO:0035603 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) |
| 2.7 | 8.0 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 2.6 | 5.2 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 2.6 | 10.3 | GO:0010645 | regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) |
| 2.5 | 32.8 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 2.5 | 2.5 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 2.5 | 37.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 2.4 | 29.4 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 2.4 | 7.3 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 2.3 | 11.4 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 2.2 | 10.9 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 2.1 | 18.7 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 2.1 | 12.4 | GO:0098707 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 2.0 | 18.3 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 2.0 | 10.1 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 2.0 | 8.1 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 2.0 | 6.1 | GO:0033512 | lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 2.0 | 16.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 2.0 | 8.1 | GO:1900106 | hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069) |
| 1.9 | 25.3 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 1.9 | 3.9 | GO:0048769 | sarcomerogenesis(GO:0048769) |
| 1.9 | 11.6 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 1.9 | 7.7 | GO:0050758 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) |
| 1.9 | 5.7 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 1.9 | 9.3 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 1.9 | 13.0 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 1.8 | 7.3 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 1.8 | 5.5 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 1.8 | 7.3 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 1.7 | 5.2 | GO:0090274 | regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274) |
| 1.7 | 34.9 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 1.7 | 7.0 | GO:0097325 | melanocyte proliferation(GO:0097325) |
| 1.7 | 11.9 | GO:0023041 | atrioventricular valve formation(GO:0003190) neuronal signal transduction(GO:0023041) |
| 1.7 | 20.3 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 1.7 | 8.4 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 1.7 | 5.0 | GO:2000295 | regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 1.7 | 6.6 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 1.7 | 5.0 | GO:1903487 | regulation of lactation(GO:1903487) |
| 1.6 | 1.6 | GO:0061518 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) |
| 1.6 | 62.8 | GO:0048665 | neuron fate specification(GO:0048665) |
| 1.6 | 9.6 | GO:0035947 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) |
| 1.6 | 11.1 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 1.6 | 7.9 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 1.6 | 6.3 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535) |
| 1.6 | 4.7 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 1.5 | 4.6 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 1.5 | 7.7 | GO:0052203 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 1.5 | 4.4 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 1.5 | 4.4 | GO:0000966 | RNA 5'-end processing(GO:0000966) |
| 1.5 | 4.4 | GO:0007525 | somatic muscle development(GO:0007525) |
| 1.4 | 2.9 | GO:0034136 | negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) |
| 1.4 | 27.1 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 1.4 | 5.7 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 1.4 | 7.0 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 1.4 | 15.4 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 1.4 | 4.2 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 1.4 | 2.8 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 1.4 | 4.1 | GO:0071400 | carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718) |
| 1.4 | 5.5 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 1.4 | 23.1 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 1.4 | 13.5 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 1.3 | 20.0 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 1.3 | 12.0 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 1.3 | 7.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.3 | 11.7 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 1.3 | 6.5 | GO:0035645 | enteric smooth muscle cell differentiation(GO:0035645) |
| 1.3 | 2.6 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 1.3 | 3.8 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 1.3 | 3.8 | GO:0030573 | bile acid catabolic process(GO:0030573) |
| 1.3 | 6.3 | GO:0015886 | heme transport(GO:0015886) |
| 1.3 | 8.8 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 1.3 | 5.0 | GO:0008272 | sulfate transport(GO:0008272) |
| 1.3 | 15.0 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 1.2 | 16.1 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 1.2 | 8.7 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 1.2 | 37.9 | GO:0098743 | cell aggregation(GO:0098743) |
| 1.2 | 3.6 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 1.2 | 7.2 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 1.2 | 4.8 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 1.2 | 13.1 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 1.2 | 1.2 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 1.2 | 4.7 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 1.2 | 3.5 | GO:0035377 | transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
| 1.2 | 5.8 | GO:0010751 | negative regulation of nitric oxide mediated signal transduction(GO:0010751) |
| 1.2 | 5.8 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 1.2 | 7.0 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 1.2 | 3.5 | GO:0003431 | growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) |
| 1.1 | 1.1 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 1.1 | 3.4 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
| 1.1 | 49.6 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 1.1 | 15.7 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 1.1 | 7.8 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728) |
| 1.1 | 3.3 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 1.1 | 4.4 | GO:0018032 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 1.1 | 2.2 | GO:1903413 | cellular response to bile acid(GO:1903413) |
| 1.1 | 9.9 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.1 | 11.0 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 1.1 | 2.2 | GO:0060214 | endocardium formation(GO:0060214) |
| 1.1 | 4.3 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 1.1 | 8.6 | GO:0051414 | response to cortisol(GO:0051414) |
| 1.1 | 10.7 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 1.1 | 4.3 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.1 | 7.4 | GO:0030421 | defecation(GO:0030421) |
| 1.1 | 17.9 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 1.1 | 8.4 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 1.0 | 18.9 | GO:0097264 | self proteolysis(GO:0097264) |
| 1.0 | 3.1 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 1.0 | 8.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 1.0 | 6.1 | GO:0036022 | limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) |
| 1.0 | 3.0 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654) |
| 1.0 | 4.0 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 1.0 | 4.0 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 1.0 | 25.5 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 1.0 | 3.9 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 1.0 | 11.6 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 1.0 | 7.7 | GO:0019732 | antifungal humoral response(GO:0019732) |
| 1.0 | 11.5 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 1.0 | 1.9 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 1.0 | 8.6 | GO:0017062 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 1.0 | 14.4 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 1.0 | 8.6 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 1.0 | 2.9 | GO:0072233 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.9 | 5.7 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.9 | 7.6 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.9 | 6.6 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.9 | 15.0 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.9 | 8.4 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
| 0.9 | 1.8 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.9 | 5.5 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.9 | 17.3 | GO:0042424 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 0.9 | 2.7 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.9 | 48.5 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.9 | 20.4 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.9 | 6.1 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.9 | 3.4 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 0.9 | 4.3 | GO:0010816 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.9 | 0.9 | GO:0035905 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.9 | 9.5 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.9 | 3.4 | GO:0015942 | formate metabolic process(GO:0015942) |
| 0.9 | 3.4 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
| 0.8 | 10.0 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.8 | 5.0 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.8 | 0.8 | GO:1902961 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.8 | 22.3 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.8 | 3.3 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
| 0.8 | 2.5 | GO:0003174 | mitral valve development(GO:0003174) mitral valve morphogenesis(GO:0003183) |
| 0.8 | 4.1 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 0.8 | 8.9 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.8 | 5.7 | GO:0086028 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
| 0.8 | 7.1 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
| 0.8 | 1.6 | GO:2000437 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 0.8 | 1.6 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.8 | 1.5 | GO:0035290 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.8 | 2.3 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 0.8 | 22.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.8 | 1.5 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.8 | 5.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.8 | 8.4 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.8 | 12.8 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.7 | 7.5 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.7 | 1.5 | GO:1904582 | mesendoderm development(GO:0048382) regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582) |
| 0.7 | 2.2 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.7 | 8.9 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.7 | 8.0 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.7 | 7.2 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.7 | 7.9 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.7 | 4.3 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.7 | 9.3 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.7 | 46.0 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.7 | 2.8 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.7 | 2.8 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.7 | 8.4 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.7 | 2.1 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 0.7 | 5.5 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.7 | 17.9 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.7 | 2.1 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.7 | 2.7 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.7 | 2.7 | GO:0072660 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.7 | 5.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.7 | 7.4 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.7 | 66.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.7 | 2.7 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 0.7 | 2.7 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.7 | 2.0 | GO:0019418 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 0.7 | 10.5 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.7 | 2.6 | GO:0042377 | menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377) |
| 0.7 | 2.6 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.6 | 4.5 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.6 | 3.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.6 | 14.8 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.6 | 20.0 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.6 | 5.1 | GO:0072498 | embryonic skeletal joint development(GO:0072498) |
| 0.6 | 1.9 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.6 | 3.2 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.6 | 22.8 | GO:0061641 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.6 | 1.9 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.6 | 1.3 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.6 | 1.9 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.6 | 3.1 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 0.6 | 2.5 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.6 | 6.8 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.6 | 7.3 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.6 | 2.4 | GO:1903935 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
| 0.6 | 2.4 | GO:0005985 | sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) |
| 0.6 | 4.2 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.6 | 1.8 | GO:0032754 | positive regulation of interleukin-5 production(GO:0032754) |
| 0.6 | 8.3 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.6 | 4.7 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.6 | 9.3 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.6 | 3.5 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.6 | 3.5 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.6 | 4.1 | GO:0015747 | urate transport(GO:0015747) |
| 0.6 | 48.3 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.6 | 2.9 | GO:1901569 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 0.6 | 2.3 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.6 | 2.9 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
| 0.6 | 3.4 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.6 | 15.3 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.6 | 1.7 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.6 | 4.5 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.6 | 10.5 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.6 | 4.4 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.6 | 2.8 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 0.5 | 2.2 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 0.5 | 4.9 | GO:0042737 | drug catabolic process(GO:0042737) |
| 0.5 | 2.2 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.5 | 6.0 | GO:2000795 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.5 | 8.7 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.5 | 4.3 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.5 | 3.7 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.5 | 4.8 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.5 | 2.1 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.5 | 3.6 | GO:0021681 | cerebellar granular layer development(GO:0021681) |
| 0.5 | 3.6 | GO:0097398 | response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398) |
| 0.5 | 0.5 | GO:0060300 | regulation of cytokine activity(GO:0060300) |
| 0.5 | 4.1 | GO:0015868 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 0.5 | 5.1 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.5 | 24.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.5 | 8.0 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.5 | 10.9 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.5 | 2.4 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.5 | 2.4 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.5 | 3.8 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.5 | 25.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.5 | 3.8 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.5 | 1.9 | GO:0001777 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.5 | 75.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.5 | 4.7 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.5 | 4.2 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.5 | 5.1 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.5 | 2.8 | GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881) |
| 0.5 | 4.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.5 | 1.4 | GO:0036047 | protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699) |
| 0.5 | 1.8 | GO:0010536 | positive regulation of activation of Janus kinase activity(GO:0010536) |
| 0.5 | 4.1 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.4 | 6.2 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.4 | 1.8 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.4 | 6.2 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.4 | 0.9 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.4 | 4.8 | GO:0002693 | positive regulation of cellular extravasation(GO:0002693) |
| 0.4 | 1.3 | GO:1902172 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.4 | 8.3 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.4 | 5.2 | GO:0009713 | catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423) |
| 0.4 | 2.6 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.4 | 14.4 | GO:0007628 | adult walking behavior(GO:0007628) |
| 0.4 | 1.3 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.4 | 1.7 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 0.4 | 10.9 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.4 | 3.8 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168) |
| 0.4 | 7.0 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.4 | 10.6 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.4 | 18.0 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.4 | 23.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.4 | 6.8 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.4 | 2.4 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.4 | 3.5 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.4 | 2.3 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.4 | 1.2 | GO:0098758 | response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) |
| 0.4 | 2.7 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
| 0.4 | 15.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.4 | 3.0 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.4 | 1.9 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) |
| 0.4 | 1.5 | GO:0048069 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) eye pigmentation(GO:0048069) |
| 0.4 | 7.0 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
| 0.4 | 1.1 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.4 | 4.4 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.4 | 2.5 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.4 | 1.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.4 | 6.7 | GO:0048011 | neurotrophin TRK receptor signaling pathway(GO:0048011) |
| 0.4 | 8.5 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.4 | 5.6 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.4 | 1.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.3 | 3.8 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.3 | 2.1 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.3 | 7.2 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.3 | 1.0 | GO:0035811 | negative regulation of urine volume(GO:0035811) |
| 0.3 | 2.4 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.3 | 7.5 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.3 | 3.7 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.3 | 5.4 | GO:0060347 | heart trabecula formation(GO:0060347) |
| 0.3 | 2.0 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 0.3 | 3.7 | GO:0045986 | negative regulation of smooth muscle contraction(GO:0045986) |
| 0.3 | 2.7 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.3 | 2.3 | GO:0051004 | regulation of lipoprotein lipase activity(GO:0051004) |
| 0.3 | 2.9 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.3 | 6.2 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.3 | 2.3 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 0.3 | 5.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.3 | 7.7 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.3 | 5.2 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.3 | 20.3 | GO:0051899 | membrane depolarization(GO:0051899) |
| 0.3 | 8.6 | GO:0051931 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.3 | 8.8 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.3 | 8.1 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.3 | 3.1 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.3 | 2.8 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.3 | 8.8 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.3 | 2.1 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.3 | 3.6 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.3 | 0.3 | GO:0009820 | alkaloid metabolic process(GO:0009820) |
| 0.3 | 4.1 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.3 | 2.6 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.3 | 0.8 | GO:0015783 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.3 | 1.4 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.3 | 2.2 | GO:0043691 | reverse cholesterol transport(GO:0043691) |
| 0.3 | 2.2 | GO:0070897 | DNA-templated transcriptional preinitiation complex assembly(GO:0070897) |
| 0.3 | 6.2 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.3 | 1.1 | GO:0019376 | galactolipid catabolic process(GO:0019376) |
| 0.3 | 2.1 | GO:0060746 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.3 | 2.9 | GO:0015871 | choline transport(GO:0015871) |
| 0.3 | 1.3 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
| 0.3 | 1.6 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.3 | 4.4 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.3 | 1.5 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.3 | 2.1 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.3 | 1.3 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.3 | 3.0 | GO:0061365 | positive regulation of triglyceride lipase activity(GO:0061365) |
| 0.2 | 1.2 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.2 | 3.1 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.2 | 0.5 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.2 | 3.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.2 | 0.7 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.2 | 3.0 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.2 | 1.2 | GO:2001205 | negative regulation of osteoclast development(GO:2001205) |
| 0.2 | 2.3 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.2 | 7.1 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.2 | 1.6 | GO:1902856 | negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.2 | 1.6 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 0.2 | 0.9 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) cloacal septation(GO:0060197) |
| 0.2 | 22.9 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.2 | 7.1 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.2 | 1.3 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 2.2 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.2 | 4.1 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.2 | 0.6 | GO:0014062 | regulation of serotonin secretion(GO:0014062) |
| 0.2 | 3.2 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.2 | 2.6 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.2 | 52.4 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.2 | 1.1 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.2 | 1.9 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.2 | 1.0 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.2 | 1.2 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.2 | 3.9 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.2 | 0.8 | GO:0010996 | response to auditory stimulus(GO:0010996) |
| 0.2 | 1.2 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.2 | 5.2 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.2 | 0.4 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.2 | 0.4 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.2 | 4.3 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.2 | 2.9 | GO:0006768 | biotin metabolic process(GO:0006768) |
| 0.2 | 1.6 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.2 | 12.7 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.2 | 1.2 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 0.2 | 8.5 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.2 | 3.5 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.2 | 0.6 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.2 | 0.2 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) |
| 0.2 | 1.3 | GO:0072386 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.2 | 4.0 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.2 | 1.5 | GO:0033327 | acrosome assembly(GO:0001675) Leydig cell differentiation(GO:0033327) |
| 0.2 | 1.4 | GO:1901841 | regulation of high voltage-gated calcium channel activity(GO:1901841) |
| 0.2 | 2.5 | GO:0035878 | nail development(GO:0035878) |
| 0.2 | 3.5 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.2 | 3.5 | GO:0034105 | positive regulation of tissue remodeling(GO:0034105) |
| 0.2 | 1.0 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 1.5 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.2 | 3.1 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.2 | 5.5 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.2 | 1.5 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.2 | 1.5 | GO:0097242 | beta-amyloid clearance(GO:0097242) |
| 0.2 | 0.2 | GO:1900020 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.2 | 0.2 | GO:0060264 | respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 0.2 | 1.6 | GO:0044849 | estrous cycle(GO:0044849) |
| 0.2 | 2.0 | GO:0006067 | ethanol metabolic process(GO:0006067) |
| 0.2 | 1.1 | GO:0042268 | regulation of cytolysis(GO:0042268) |
| 0.2 | 0.8 | GO:0048840 | otolith development(GO:0048840) |
| 0.2 | 1.0 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
| 0.2 | 2.7 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.2 | 1.4 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.2 | 0.6 | GO:0021615 | glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.2 | 0.8 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.2 | 1.7 | GO:1903944 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.2 | 2.3 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.1 | 1.3 | GO:0030007 | cellular potassium ion homeostasis(GO:0030007) response to carbon monoxide(GO:0034465) |
| 0.1 | 2.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.6 | GO:0045423 | granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) |
| 0.1 | 0.9 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 1.0 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.1 | 1.4 | GO:0044550 | secondary metabolite biosynthetic process(GO:0044550) |
| 0.1 | 1.6 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.1 | 6.6 | GO:0002548 | monocyte chemotaxis(GO:0002548) |
| 0.1 | 8.0 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.1 | 1.4 | GO:1903392 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392) |
| 0.1 | 0.8 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.1 | 4.5 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 2.9 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 4.0 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.1 | 1.7 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 0.4 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.1 | 2.1 | GO:0042104 | positive regulation of activated T cell proliferation(GO:0042104) |
| 0.1 | 8.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 1.0 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 10.4 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.1 | 0.4 | GO:1904907 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.1 | 1.2 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 5.1 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.1 | 9.9 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.1 | 0.4 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.1 | 0.4 | GO:1903568 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.1 | 1.3 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 0.4 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.1 | 0.5 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 2.0 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.1 | 1.4 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.1 | 1.0 | GO:0034391 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.1 | 0.5 | GO:0090116 | DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.1 | 1.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 4.9 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.1 | 13.9 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.1 | 1.6 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 0.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 0.5 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.1 | 5.8 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.1 | 27.2 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.1 | 2.4 | GO:0061028 | establishment of endothelial barrier(GO:0061028) |
| 0.1 | 6.4 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
| 0.1 | 3.9 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 5.8 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.1 | 2.3 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.1 | 1.8 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 3.4 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.1 | 4.0 | GO:0021954 | central nervous system neuron development(GO:0021954) |
| 0.1 | 1.6 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.1 | 1.0 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.6 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.1 | 0.5 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 3.0 | GO:0006506 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 1.0 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.1 | 4.7 | GO:0017156 | calcium ion regulated exocytosis(GO:0017156) |
| 0.1 | 2.5 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.1 | 1.0 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.1 | 0.9 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.1 | 0.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 0.5 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.6 | GO:0030815 | negative regulation of cAMP metabolic process(GO:0030815) |
| 0.1 | 2.0 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 1.0 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.1 | 1.6 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.1 | 1.4 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.1 | 0.9 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 2.1 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.1 | 1.9 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.2 | GO:0048799 | organ maturation(GO:0048799) |
| 0.1 | 2.8 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.1 | 2.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.1 | 1.4 | GO:0046135 | pyrimidine nucleoside catabolic process(GO:0046135) |
| 0.1 | 0.2 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) |
| 0.0 | 1.7 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.0 | 0.2 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 1.9 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.0 | 0.5 | GO:0046320 | regulation of fatty acid oxidation(GO:0046320) |
| 0.0 | 1.1 | GO:0048814 | regulation of dendrite morphogenesis(GO:0048814) |
| 0.0 | 0.6 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.0 | 0.2 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.0 | 0.6 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.0 | 0.4 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 0.8 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 1.3 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 1.5 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 0.1 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.0 | 0.6 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.0 | 0.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 0.5 | GO:0030317 | sperm motility(GO:0030317) |
| 0.0 | 0.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.1 | GO:0007501 | mesodermal cell fate specification(GO:0007501) |
| 0.0 | 0.2 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.0 | 0.1 | GO:0048251 | elastic fiber assembly(GO:0048251) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.5 | 215.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 11.3 | 45.3 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 11.3 | 45.1 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 9.7 | 125.7 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 6.8 | 20.3 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 6.1 | 123.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 6.1 | 24.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 5.9 | 29.4 | GO:0031673 | H zone(GO:0031673) |
| 5.8 | 87.3 | GO:0030478 | actin cap(GO:0030478) |
| 5.3 | 26.3 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 4.7 | 18.9 | GO:0071546 | pi-body(GO:0071546) |
| 4.7 | 14.0 | GO:0070701 | mucus layer(GO:0070701) |
| 4.2 | 12.6 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 4.0 | 16.1 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 3.8 | 30.4 | GO:0005579 | membrane attack complex(GO:0005579) |
| 3.0 | 9.0 | GO:0016938 | kinesin I complex(GO:0016938) |
| 3.0 | 18.0 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 2.9 | 8.8 | GO:0036398 | TCR signalosome(GO:0036398) |
| 2.8 | 17.1 | GO:0033269 | internode region of axon(GO:0033269) |
| 2.8 | 8.4 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 2.7 | 13.5 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 2.5 | 14.8 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 2.4 | 21.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 2.3 | 7.0 | GO:0044609 | DBIRD complex(GO:0044609) |
| 2.1 | 10.7 | GO:0044218 | growing cell tip(GO:0035838) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 2.0 | 8.0 | GO:0033263 | CORVET complex(GO:0033263) |
| 1.9 | 9.5 | GO:0005712 | chiasma(GO:0005712) |
| 1.8 | 25.6 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 1.8 | 19.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 1.6 | 6.4 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 1.5 | 12.2 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 1.4 | 18.6 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 1.4 | 16.6 | GO:0016013 | syntrophin complex(GO:0016013) |
| 1.3 | 16.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.2 | 30.0 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 1.2 | 3.5 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 1.2 | 3.5 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 1.1 | 3.4 | GO:0033150 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 1.1 | 14.6 | GO:0042583 | chromaffin granule(GO:0042583) |
| 1.1 | 54.8 | GO:0031430 | M band(GO:0031430) |
| 1.1 | 4.3 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 1.1 | 12.9 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 1.0 | 6.0 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 1.0 | 103.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 1.0 | 17.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 1.0 | 3.8 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.9 | 37.7 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.9 | 37.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.9 | 4.3 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.9 | 2.6 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.8 | 7.6 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.8 | 4.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.8 | 9.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.8 | 14.6 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.8 | 5.7 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.8 | 5.7 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.8 | 13.0 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.8 | 14.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.8 | 12.0 | GO:0032982 | myosin filament(GO:0032982) |
| 0.8 | 6.2 | GO:0043203 | axon hillock(GO:0043203) |
| 0.8 | 6.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.7 | 8.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.7 | 4.4 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.7 | 10.9 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.7 | 277.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.7 | 5.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.7 | 152.9 | GO:0030426 | growth cone(GO:0030426) |
| 0.7 | 3.5 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.7 | 17.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.7 | 63.8 | GO:0005776 | autophagosome(GO:0005776) |
| 0.7 | 4.7 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.7 | 5.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.6 | 38.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.6 | 11.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.6 | 1.2 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.6 | 4.8 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.6 | 2.9 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.6 | 3.5 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.6 | 5.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.6 | 15.0 | GO:0071437 | invadopodium(GO:0071437) |
| 0.6 | 4.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.5 | 3.8 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.5 | 3.8 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.5 | 10.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.5 | 6.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.5 | 29.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.5 | 2.1 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.5 | 104.6 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.5 | 3.1 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.5 | 4.0 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.5 | 10.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.5 | 1.5 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.5 | 18.3 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.5 | 5.6 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.5 | 19.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.4 | 1.3 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.4 | 2.1 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.4 | 2.9 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.4 | 19.7 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
| 0.4 | 7.8 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 0.4 | 1.9 | GO:0089701 | U2AF(GO:0089701) |
| 0.4 | 5.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.4 | 9.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.4 | 10.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.4 | 9.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.4 | 3.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.4 | 10.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.3 | 92.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.3 | 7.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.3 | 4.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.3 | 1.0 | GO:0030689 | Noc complex(GO:0030689) |
| 0.3 | 10.1 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.3 | 10.3 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.3 | 4.2 | GO:0097433 | dense body(GO:0097433) |
| 0.3 | 8.3 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.3 | 20.2 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.3 | 7.2 | GO:0036379 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.3 | 3.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.3 | 1.4 | GO:0030315 | T-tubule(GO:0030315) |
| 0.3 | 2.5 | GO:0070449 | elongin complex(GO:0070449) |
| 0.3 | 45.8 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.3 | 1.0 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.3 | 2.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.3 | 1.3 | GO:0045179 | apical cortex(GO:0045179) |
| 0.2 | 1.2 | GO:0016589 | NURF complex(GO:0016589) |
| 0.2 | 9.6 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.2 | 6.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.2 | 2.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.2 | 2.4 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 7.7 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.2 | 29.9 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.2 | 2.5 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.2 | 17.1 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.2 | 1.8 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.2 | 0.8 | GO:0071942 | XPC complex(GO:0071942) |
| 0.2 | 0.6 | GO:0098636 | protein complex involved in cell adhesion(GO:0098636) |
| 0.2 | 6.8 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.2 | 1.9 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.2 | 18.4 | GO:0030018 | Z disc(GO:0030018) |
| 0.2 | 10.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 0.9 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.2 | 11.8 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.2 | 0.4 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.2 | 18.2 | GO:0043204 | perikaryon(GO:0043204) |
| 0.2 | 0.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.2 | 0.5 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.2 | 0.5 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
| 0.2 | 3.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.2 | 2.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 4.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.2 | 2.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.2 | 17.0 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.2 | 0.9 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.2 | 0.6 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.1 | 0.6 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 0.9 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 10.0 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 24.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 2.1 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 5.2 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 5.9 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.1 | 4.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 3.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.4 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.1 | 3.1 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 9.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 3.1 | GO:0032421 | stereocilium bundle(GO:0032421) |
| 0.1 | 5.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 5.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 0.5 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.1 | 5.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 1.8 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 3.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.1 | 0.4 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.1 | 1.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 0.7 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.3 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.5 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 3.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 2.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 5.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 3.4 | GO:0034358 | protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777) |
| 0.1 | 1.5 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 2.6 | GO:0098793 | presynapse(GO:0098793) |
| 0.1 | 1.4 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.1 | 6.7 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.1 | 76.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.1 | 5.0 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 1.4 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.1 | 5.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 11.4 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.3 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 0.2 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.3 | GO:0030016 | myofibril(GO:0030016) |
| 0.0 | 3.3 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.8 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 23.5 | 70.5 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 18.0 | 72.0 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 7.1 | 214.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 6.9 | 82.2 | GO:0008430 | selenium binding(GO:0008430) |
| 6.8 | 143.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 6.4 | 19.3 | GO:0004877 | complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877) |
| 5.5 | 16.6 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 5.5 | 32.8 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 5.3 | 26.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 5.1 | 20.2 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 5.0 | 15.0 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 4.8 | 67.7 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 4.8 | 14.5 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 4.7 | 18.9 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 4.6 | 13.7 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 4.5 | 13.5 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 4.2 | 16.9 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 4.2 | 12.6 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 4.1 | 12.2 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 3.8 | 26.6 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 3.6 | 10.9 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 3.6 | 3.6 | GO:0070052 | collagen V binding(GO:0070052) |
| 3.6 | 10.7 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 3.3 | 16.6 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 3.2 | 277.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 3.0 | 11.9 | GO:0047708 | biotinidase activity(GO:0047708) |
| 2.8 | 50.6 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 2.7 | 74.0 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 2.6 | 7.9 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 2.6 | 15.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 2.5 | 10.0 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 2.5 | 32.3 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 2.3 | 9.1 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 2.1 | 10.7 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 2.1 | 2.1 | GO:0001855 | complement component C4b binding(GO:0001855) |
| 2.0 | 6.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 2.0 | 13.7 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 1.9 | 17.3 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 1.9 | 5.7 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 1.9 | 17.0 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 1.9 | 14.8 | GO:0015232 | heme transporter activity(GO:0015232) |
| 1.8 | 14.8 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.8 | 28.3 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 1.7 | 12.2 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 1.7 | 10.3 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
| 1.7 | 51.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 1.7 | 5.0 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 1.6 | 19.5 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 1.6 | 4.8 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 1.6 | 4.7 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 1.6 | 15.7 | GO:0015386 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 1.6 | 24.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 1.5 | 15.0 | GO:0042910 | xenobiotic transporter activity(GO:0042910) |
| 1.5 | 16.1 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 1.4 | 2.9 | GO:0052871 | leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 1.4 | 17.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 1.4 | 15.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 1.4 | 4.2 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 1.4 | 16.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 1.3 | 6.5 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 1.3 | 18.1 | GO:0045159 | myosin II binding(GO:0045159) |
| 1.3 | 21.9 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 1.3 | 6.3 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 1.3 | 3.8 | GO:0035375 | zymogen binding(GO:0035375) |
| 1.3 | 6.3 | GO:1903135 | cupric ion binding(GO:1903135) |
| 1.2 | 7.4 | GO:0017098 | sulfonylurea receptor binding(GO:0017098) |
| 1.2 | 30.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 1.2 | 16.9 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 1.2 | 14.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 1.2 | 3.5 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 1.1 | 4.6 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 1.1 | 35.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 1.1 | 5.7 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 1.1 | 3.4 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 1.1 | 2.3 | GO:0070330 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330) |
| 1.1 | 11.3 | GO:0005549 | odorant binding(GO:0005549) |
| 1.1 | 4.5 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 1.1 | 22.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 1.1 | 25.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 1.1 | 4.4 | GO:0004598 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 1.1 | 14.1 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 1.1 | 15.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 1.1 | 3.2 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 1.1 | 3.2 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 1.1 | 9.5 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 1.0 | 18.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 1.0 | 3.1 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 1.0 | 5.2 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 1.0 | 3.1 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 1.0 | 19.8 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 1.0 | 33.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 1.0 | 8.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 1.0 | 4.1 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 1.0 | 4.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 1.0 | 11.1 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 1.0 | 4.0 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
| 1.0 | 21.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 1.0 | 64.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 1.0 | 8.7 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 1.0 | 4.8 | GO:0051120 | hepoxilin A3 synthase activity(GO:0051120) |
| 1.0 | 20.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.9 | 1.9 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
| 0.9 | 17.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.9 | 2.7 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.9 | 4.6 | GO:0004803 | transposase activity(GO:0004803) |
| 0.9 | 7.3 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.9 | 8.2 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.9 | 1.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.9 | 15.4 | GO:0031432 | titin binding(GO:0031432) |
| 0.9 | 2.7 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.9 | 4.4 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.9 | 20.0 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.9 | 12.8 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.9 | 5.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.8 | 20.2 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.8 | 2.5 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.8 | 17.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.8 | 11.9 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.8 | 4.0 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.8 | 23.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.8 | 10.9 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.8 | 7.7 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.8 | 2.3 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.8 | 9.2 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.8 | 10.7 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.8 | 4.5 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.8 | 13.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.8 | 6.0 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.8 | 14.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.7 | 3.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.7 | 2.9 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.7 | 9.6 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.7 | 2.9 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.7 | 11.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.7 | 14.6 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.7 | 4.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.7 | 2.9 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.7 | 2.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.7 | 7.7 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.7 | 4.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.7 | 9.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.7 | 2.1 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 0.7 | 2.1 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 0.7 | 8.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.7 | 8.1 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.7 | 24.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.7 | 2.7 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.7 | 2.6 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.7 | 5.2 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.6 | 3.9 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.6 | 1.9 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.6 | 1.9 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.6 | 1.3 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.6 | 10.0 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.6 | 4.4 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.6 | 8.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.6 | 3.1 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 0.6 | 9.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.6 | 2.4 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 0.6 | 2.4 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.6 | 55.6 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.6 | 4.7 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.6 | 3.5 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.6 | 5.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.6 | 2.3 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.6 | 1.1 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.6 | 43.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.6 | 34.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.6 | 5.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.6 | 4.5 | GO:0043426 | MRF binding(GO:0043426) |
| 0.6 | 2.2 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.6 | 3.9 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.6 | 58.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.6 | 3.9 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.5 | 1.6 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.5 | 6.4 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.5 | 1.6 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.5 | 1.5 | GO:0030272 | 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272) |
| 0.5 | 5.1 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.5 | 35.8 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.5 | 37.6 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.5 | 2.0 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.5 | 3.0 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.5 | 1.5 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.5 | 1.9 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.5 | 8.6 | GO:0070513 | death domain binding(GO:0070513) |
| 0.5 | 7.1 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.5 | 1.9 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.5 | 10.3 | GO:0005537 | mannose binding(GO:0005537) |
| 0.5 | 0.5 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.5 | 1.4 | GO:0016154 | thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154) |
| 0.5 | 10.7 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.5 | 79.8 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.5 | 1.4 | GO:0036054 | protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697) |
| 0.5 | 3.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.5 | 4.1 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.5 | 4.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.4 | 3.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.4 | 2.2 | GO:0001016 | RNA polymerase III regulatory region DNA binding(GO:0001016) |
| 0.4 | 1.3 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.4 | 28.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.4 | 0.8 | GO:0031781 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.4 | 7.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.4 | 9.5 | GO:0019825 | oxygen binding(GO:0019825) |
| 0.4 | 2.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.4 | 49.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.4 | 1.6 | GO:0008035 | high-density lipoprotein particle binding(GO:0008035) |
| 0.4 | 10.5 | GO:0042166 | acetylcholine binding(GO:0042166) |
| 0.4 | 12.4 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.4 | 1.9 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.4 | 5.7 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.4 | 12.1 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.4 | 10.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.4 | 12.1 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.4 | 2.6 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.4 | 2.2 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.4 | 5.5 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.4 | 6.6 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.4 | 4.4 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.4 | 20.1 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 0.4 | 1.4 | GO:0046573 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.4 | 1.1 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.4 | 19.7 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.3 | 3.5 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.3 | 1.7 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.3 | 7.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.3 | 4.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.3 | 2.0 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.3 | 2.7 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.3 | 5.7 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.3 | 16.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.3 | 3.4 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.3 | 1.5 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) |
| 0.3 | 2.4 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.3 | 13.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.3 | 0.3 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.3 | 2.9 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.3 | 28.7 | GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) |
| 0.3 | 1.4 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.3 | 13.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.3 | 1.1 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.3 | 29.9 | GO:0008201 | heparin binding(GO:0008201) |
| 0.3 | 2.3 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.3 | 3.4 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.3 | 1.4 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.3 | 4.5 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.3 | 0.8 | GO:0036080 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.3 | 1.4 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.3 | 9.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.3 | 3.8 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.3 | 1.1 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.3 | 9.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.3 | 2.6 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.3 | 2.9 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.3 | 0.5 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.3 | 1.8 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.2 | 21.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.2 | 4.7 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.2 | 8.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.2 | 2.4 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.2 | 8.0 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 8.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.2 | 8.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 1.4 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.2 | 3.9 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.2 | 2.7 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.2 | 3.7 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.2 | 3.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.2 | 0.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 16.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 2.8 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.2 | 3.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 0.6 | GO:0004577 | N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577) |
| 0.2 | 0.8 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.2 | 2.2 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.2 | 7.1 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.2 | 1.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.2 | 0.6 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 0.2 | 2.2 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.2 | 0.6 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.2 | 0.9 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.2 | 1.3 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 1.4 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.2 | 1.2 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.2 | 1.2 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.2 | 1.3 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.2 | 2.3 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.2 | 3.8 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.2 | 4.7 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.2 | 1.5 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.2 | 3.4 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.2 | 1.8 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 2.1 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.1 | 0.3 | GO:0010465 | neurotrophin receptor activity(GO:0005030) nerve growth factor receptor activity(GO:0010465) |
| 0.1 | 1.1 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 6.8 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 1.0 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 3.4 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 0.5 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.1 | 12.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 24.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 6.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 0.4 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.1 | 0.5 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 0.4 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 2.9 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 1.5 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 1.3 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
| 0.1 | 4.8 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.6 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.1 | 0.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 1.1 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.1 | 1.8 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 1.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 5.0 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 5.1 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.1 | 3.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 11.3 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 1.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 1.0 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.1 | 4.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 0.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 2.1 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.1 | 3.2 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 0.4 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.1 | 3.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 1.0 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 2.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 0.9 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.2 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.1 | 1.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 1.0 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.1 | 1.1 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 0.9 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 1.7 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.1 | 5.6 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 1.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.7 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 7.4 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 2.4 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 1.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 1.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 1.9 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 0.3 | GO:0043559 | insulin binding(GO:0043559) |
| 0.1 | 1.7 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 1.2 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.0 | 1.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.0 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.8 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 4.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.2 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.0 | 0.7 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.4 | GO:0022840 | leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842) |
| 0.0 | 1.9 | GO:1901476 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
| 0.0 | 2.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 1.6 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.6 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 1.1 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 7.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 0.3 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.2 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.1 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.0 | 0.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 114.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 1.9 | 7.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 1.8 | 9.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 1.1 | 244.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 1.0 | 17.7 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.9 | 140.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.9 | 21.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.8 | 53.1 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.8 | 38.0 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.7 | 14.9 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.6 | 9.3 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.6 | 106.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.6 | 85.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.5 | 141.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.5 | 26.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.5 | 12.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.5 | 9.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.5 | 16.3 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.5 | 8.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.5 | 28.1 | PID FGF PATHWAY | FGF signaling pathway |
| 0.5 | 26.1 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.4 | 25.1 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.4 | 3.0 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.4 | 3.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.4 | 10.9 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.4 | 7.1 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.4 | 12.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.4 | 23.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.4 | 3.6 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.4 | 5.6 | ST ADRENERGIC | Adrenergic Pathway |
| 0.3 | 4.4 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.3 | 5.6 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.3 | 9.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.3 | 4.3 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.3 | 1.5 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.3 | 17.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.3 | 14.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.3 | 14.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.3 | 9.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.3 | 10.9 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.3 | 0.6 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.2 | 13.1 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.2 | 13.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 14.4 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.2 | 6.8 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.2 | 3.8 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.2 | 2.6 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.2 | 1.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.2 | 8.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 2.6 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 3.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 1.4 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 3.8 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.1 | 2.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 2.1 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 0.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 2.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 6.5 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 8.0 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 1.3 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 4.3 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 0.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 0.9 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 1.2 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.1 | 1.8 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 2.0 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 2.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 0.5 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 97.9 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 4.3 | 116.4 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 3.3 | 79.7 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 3.2 | 50.6 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 2.8 | 11.2 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 1.9 | 106.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 1.9 | 41.1 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 1.8 | 131.8 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 1.7 | 40.3 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 1.5 | 68.5 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 1.5 | 35.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 1.3 | 17.8 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 1.1 | 31.9 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.9 | 35.7 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.9 | 24.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.9 | 16.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.8 | 9.2 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.8 | 14.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.7 | 14.1 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.7 | 19.8 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.7 | 54.4 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.7 | 6.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.7 | 60.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.7 | 17.1 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.6 | 11.4 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.6 | 14.5 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.6 | 4.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.6 | 7.1 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.6 | 24.8 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.6 | 16.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.6 | 24.4 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.6 | 6.4 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.6 | 6.4 | REACTOME OPSINS | Genes involved in Opsins |
| 0.6 | 22.2 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.6 | 7.3 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.6 | 81.6 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.5 | 7.6 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.5 | 15.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.5 | 12.3 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.5 | 27.0 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.5 | 8.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.5 | 7.7 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.5 | 5.6 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.5 | 10.5 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.5 | 7.7 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.5 | 17.1 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.5 | 20.4 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.5 | 15.8 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.4 | 12.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.4 | 7.0 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.4 | 20.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.4 | 2.5 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.4 | 18.0 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.4 | 7.2 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.4 | 20.9 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.4 | 6.8 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.4 | 4.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.4 | 4.4 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.4 | 8.7 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.4 | 4.6 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.3 | 4.2 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.3 | 5.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.3 | 2.3 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 11.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.3 | 9.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 3.4 | REACTOME DEVELOPMENTAL BIOLOGY | Genes involved in Developmental Biology |
| 0.3 | 6.6 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.3 | 8.7 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.3 | 5.2 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.3 | 2.7 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.3 | 4.5 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.3 | 4.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.3 | 3.4 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 2.2 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.2 | 3.4 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.2 | 4.3 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.2 | 12.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 7.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 5.6 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.2 | 6.2 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.2 | 5.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.2 | 1.0 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.2 | 2.5 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.2 | 3.8 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 1.6 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.2 | 3.4 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 4.2 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 26.6 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.2 | 3.4 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 0.5 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 3.5 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 2.9 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.1 | 1.9 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 3.3 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 2.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.4 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 3.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 2.8 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 2.9 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.1 | 3.2 | REACTOME CELL CELL JUNCTION ORGANIZATION | Genes involved in Cell-cell junction organization |
| 0.1 | 1.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 3.3 | REACTOME RNA POL III TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
| 0.1 | 1.6 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 3.9 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 7.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 0.9 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.1 | 0.8 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 1.7 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 1.3 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.6 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.0 | 0.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.7 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.3 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.2 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.8 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.1 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |