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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXL1

Z-value: 7.86

Motif logo

Transcription factors associated with FOXL1

Gene Symbol Gene ID Gene Info
ENSG00000176678.6 FOXL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXL1hg38_v1_chr16_+_86578543_865785550.372.3e-08Click!

Activity profile of FOXL1 motif

Sorted Z-values of FOXL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXL1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_90069662 52.21 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_89160329 47.50 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr12_+_69348372 46.02 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
lysozyme
chr12_-_91180365 45.21 ENST00000547937.5
decorin
chr12_-_91179472 39.62 ENST00000550099.5
ENST00000546391.5
decorin
chr2_-_88992903 33.77 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr6_+_33080445 33.76 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr12_-_91179517 30.25 ENST00000551354.1
decorin
chr22_+_22900976 30.20 ENST00000390323.2
immunoglobulin lambda constant 2
chr2_+_90021567 29.09 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_-_91153149 28.82 ENST00000550758.1
decorin
chr6_-_32589833 27.91 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr4_-_70666492 27.78 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr4_-_99352754 27.25 ENST00000639454.1
alcohol dehydrogenase 1B (class I), beta polypeptide
chr7_+_142791635 27.17 ENST00000633705.1
T cell receptor beta constant 1
chr2_-_89320146 26.99 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr2_-_89222461 26.93 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr1_+_116754422 26.92 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr2_+_89936859 26.54 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr2_-_89100352 25.55 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr12_-_91179355 25.19 ENST00000550563.5
ENST00000546370.5
decorin
chr14_-_106470788 24.10 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr11_-_5227063 23.18 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr8_-_81483226 22.24 ENST00000256104.5
fatty acid binding protein 4
chr4_-_99321362 22.06 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr2_+_89862438 21.94 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr12_-_91178520 21.66 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr14_-_106025628 21.64 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr2_-_89245596 20.83 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr14_-_106675544 20.79 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr16_+_33802683 19.90 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_-_88947820 19.79 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr4_+_70383123 19.74 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr2_-_89213917 19.00 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr14_-_106593319 18.69 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr6_+_32741382 18.54 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr2_+_90209873 18.46 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr12_-_14961559 18.36 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr14_-_106185387 17.56 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr2_+_90154073 17.56 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr2_+_188974364 17.38 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr2_+_88885397 16.94 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr14_-_106538331 16.67 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr2_+_90159840 16.23 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr4_+_69995958 15.91 ENST00000381060.2
ENST00000246895.9
statherin
chr1_-_9943314 15.83 ENST00000377223.6
ENST00000377213.1
leucine zipper and CTNNBIP1 domain containing
chr2_+_90220727 15.68 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr12_-_11310420 15.53 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr2_-_89117844 15.29 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr3_+_189789672 15.06 ENST00000434928.5
tumor protein p63
chr16_-_33845229 14.79 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr1_+_103750406 14.75 ENST00000370079.3
amylase alpha 1C
chr22_-_17221841 14.69 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
adenosine deaminase 2
chrX_+_1591590 14.56 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr12_-_7503744 14.46 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr11_-_59866478 14.32 ENST00000257264.4
transcobalamin 1
chr2_-_89143133 14.15 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr14_-_106658251 14.12 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr14_-_106360320 14.11 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr9_-_92482350 13.98 ENST00000375543.2
asporin
chr2_+_89884740 13.93 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr3_+_111292719 13.82 ENST00000460744.1
CD96 molecule
chr14_-_106269133 13.77 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr9_-_21368962 13.73 ENST00000610660.1
interferon alpha 13
chr2_+_89913982 13.28 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr12_-_7503841 12.96 ENST00000359156.8
CD163 molecule
chr12_-_11395556 12.94 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr3_-_195583931 12.91 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr4_-_99352730 12.89 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr1_-_35769958 12.87 ENST00000251195.9
ENST00000318121.8
claspin
chr4_-_185956652 12.84 ENST00000355634.9
sorbin and SH3 domain containing 2
chr6_-_32941018 12.38 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chrX_-_119943732 12.24 ENST00000371410.5
NFKB activating protein
chr9_-_92482499 12.21 ENST00000375544.7
asporin
chr10_-_67838019 12.00 ENST00000483798.6
DnaJ heat shock protein family (Hsp40) member C12
chr14_-_105940235 11.81 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr14_+_21990357 11.79 ENST00000390444.1
T cell receptor alpha variable 16
chr2_+_90082635 11.70 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr12_-_10849464 11.61 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr14_-_106062670 11.60 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr3_+_8501846 11.46 ENST00000454244.4
LIM and cysteine rich domains 1
chr3_-_121660892 11.25 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr3_+_151814102 11.23 ENST00000232892.12
arylacetamide deacetylase
chr4_+_40197023 10.85 ENST00000381799.10
ras homolog family member H
chr4_-_83114715 10.84 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr12_-_14951106 10.62 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr11_+_6863057 10.51 ENST00000641461.1
olfactory receptor family 10 subfamily A member 2
chr19_+_9185594 10.44 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr17_-_69150062 10.42 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr2_+_90234809 10.18 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr2_-_89268506 10.08 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr1_-_161307420 9.97 ENST00000491222.5
ENST00000672287.2
myelin protein zero
chr11_-_5234475 9.80 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr5_-_140633690 9.69 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr1_+_196652022 9.69 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
complement factor H
chr2_+_89959979 9.68 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr18_+_44680093 9.58 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chrY_+_2841594 9.49 ENST00000250784.13
ribosomal protein S4 Y-linked 1
chr19_-_9219589 9.46 ENST00000641244.1
ENST00000641669.1
olfactory receptor family 7 subfamily D member 4
chr2_+_90114838 9.44 ENST00000417279.3
immunoglobulin kappa variable 3D-15
chr6_-_33069242 9.42 ENST00000437811.1
major histocompatibility complex, class II, DP alpha 1
chr4_+_70195719 9.42 ENST00000683306.1
odontogenic, ameloblast associated
chr14_-_105987068 9.31 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr4_+_87832917 9.26 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr2_+_89947508 9.20 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr14_-_106622837 9.09 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr2_-_86105839 9.06 ENST00000263857.11
RNA polymerase I subunit A
chr17_+_56978111 8.94 ENST00000262288.8
ENST00000572710.5
ENST00000575395.5
ENST00000631024.1
serine carboxypeptidase 1
chr2_+_238138661 8.93 ENST00000409223.2
kelch like family member 30
chr4_+_105710809 8.90 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr11_-_85665077 8.86 ENST00000527447.2
CREB/ATF bZIP transcription factor
chr14_-_106811131 8.80 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr4_-_99435336 8.80 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_113406368 8.70 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr9_+_98943705 8.60 ENST00000610452.1
collagen type XV alpha 1 chain
chr14_-_106324743 8.57 ENST00000390612.3
immunoglobulin heavy variable 4-28
chr8_-_85341705 8.57 ENST00000517618.5
carbonic anhydrase 1
chr3_+_187024614 8.52 ENST00000416235.6
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr10_-_43574555 8.45 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr1_+_207325629 8.43 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr17_-_31314040 8.43 ENST00000330927.5
ecotropic viral integration site 2B
chr16_-_3372666 8.38 ENST00000399974.5
MT-RNR2 like 4
chr15_-_21718245 8.35 ENST00000630556.1
novel gene identicle to IGHV1OR15-1
chr14_-_106511856 8.26 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr15_-_19988117 7.96 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr1_+_196819731 7.88 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr11_-_13496018 7.88 ENST00000529816.1
parathyroid hormone
chr14_-_106277039 7.85 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr7_+_80646436 7.71 ENST00000419819.2
CD36 molecule
chr13_-_37598750 7.70 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr4_-_69961007 7.67 ENST00000353151.3
casein beta
chr2_-_206086057 7.65 ENST00000403263.6
INO80 complex subunit D
chr14_-_106737547 7.56 ENST00000632209.1
immunoglobulin heavy variable 1-69-2
chr12_-_10884244 7.53 ENST00000543626.4
proline rich protein HaeIII subfamily 1
chr10_-_69409275 7.51 ENST00000373307.5
tachykinin receptor 2
chr1_+_207053229 7.50 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr7_-_38249572 7.47 ENST00000436911.6
T cell receptor gamma constant 2
chr16_+_72056153 7.46 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
haptoglobin
chr3_+_38496467 7.42 ENST00000453767.1
exo/endonuclease G
chr19_+_35995176 7.41 ENST00000378887.4
succinate dehydrogenase complex assembly factor 1
chr14_-_106235582 7.35 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr6_-_27912396 7.31 ENST00000303324.4
olfactory receptor family 2 subfamily B member 2
chr10_+_114239245 7.30 ENST00000392982.8
von Willebrand factor A domain containing 2
chr10_+_94762673 7.27 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr1_-_207052980 7.27 ENST00000367084.1
YOD1 deubiquitinase
chr14_-_106639589 7.19 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr6_+_131250375 7.16 ENST00000474850.2
A-kinase anchoring protein 7
chr3_+_138347648 7.13 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chr2_-_162152404 7.13 ENST00000375497.3
glucagon
chr2_-_152098810 7.12 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr9_+_137742957 7.10 ENST00000637318.1
ENST00000478940.1
euchromatic histone lysine methyltransferase 1
chr4_+_67558719 7.02 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr8_+_24294044 6.93 ENST00000265769.9
ADAM metallopeptidase domain 28
chr14_-_106389858 6.86 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr4_+_70360751 6.85 ENST00000226460.5
submaxillary gland androgen regulated protein 3A
chr15_-_21742799 6.83 ENST00000622410.2
novel protein, identical to IGHV4-4
chr14_-_106165730 6.81 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr6_-_169250825 6.76 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr11_-_60183191 6.75 ENST00000412309.6
membrane spanning 4-domains A6A
chr13_-_46438190 6.73 ENST00000409879.6
rubicon like autophagy enhancer
chr6_-_116126120 6.70 ENST00000452729.1
ENST00000651968.1
ENST00000243222.8
collagen type X alpha 1 chain
chr22_+_22322452 6.67 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr12_+_71686473 6.61 ENST00000549735.5
transmembrane protein 19
chr1_+_198638968 6.59 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chrX_-_57910458 6.57 ENST00000358697.6
zinc finger X-linked duplicated A
chr16_-_1611985 6.54 ENST00000426508.7
intraflagellar transport 140
chr4_+_70430487 6.53 ENST00000413702.5
mucin 7, secreted
chr6_-_169253835 6.52 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr1_-_163202835 6.51 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chrX_+_37780049 6.51 ENST00000378588.5
cytochrome b-245 beta chain
chr18_+_31447732 6.50 ENST00000257189.5
desmoglein 3
chr4_+_70397931 6.50 ENST00000399575.7
opiorphin prepropeptide
chr12_+_133181409 6.45 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
zinc finger protein 268
chr22_+_22380766 6.45 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr5_-_39425187 6.39 ENST00000545653.5
DAB adaptor protein 2
chr9_-_92536031 6.38 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr10_+_122560679 6.35 ENST00000657942.1
deleted in malignant brain tumors 1
chr5_-_170297746 6.33 ENST00000046794.10
lymphocyte cytosolic protein 2
chr1_+_13583762 6.26 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr19_+_54769785 6.25 ENST00000336077.11
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
chr4_-_99290975 6.21 ENST00000209668.3
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr10_-_96271508 6.20 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr5_-_79991237 6.17 ENST00000512560.5
ENST00000509852.6
ENST00000512528.3
ENST00000617335.4
metaxin 3
chr14_-_106088573 6.15 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr19_-_54364863 6.14 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr7_-_150341615 6.09 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
retinoic acid receptor responder 2
chr8_+_93754844 6.06 ENST00000684064.1
ENST00000498673.5
ENST00000518319.5
transmembrane protein 67
chr3_+_119186716 6.05 ENST00000460625.1
uroplakin 1B
chr14_-_106557465 6.04 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr1_+_158931539 6.02 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
pyrin and HIN domain family member 1
chr8_-_85341659 6.01 ENST00000522389.5
carbonic anhydrase 1
chr4_+_73404255 5.93 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
albumin
chr1_-_89126066 5.87 ENST00000370466.4
guanylate binding protein 2
chr8_+_93754879 5.86 ENST00000453906.6
ENST00000683362.1
ENST00000682036.1
ENST00000453321.8
ENST00000409623.8
ENST00000520680.2
ENST00000521517.6
ENST00000452276.6
transmembrane protein 67
chr16_+_19285724 5.82 ENST00000636231.2
ENST00000493231.5
ENST00000465414.1
C-type lectin domain containing 19A
chr6_-_131951364 5.82 ENST00000367976.4
cellular communication network factor 2
chr15_-_45378519 5.80 ENST00000558163.1
ENST00000396659.8
ENST00000675323.1
ENST00000558336.5
glycine amidinotransferase
chr5_+_141408000 5.78 ENST00000616430.1
protocadherin gamma subfamily B, 6
chr19_+_36605292 5.77 ENST00000460670.5
ENST00000292928.7
ENST00000439428.5
zinc finger protein 382
chr12_+_8843236 5.71 ENST00000541459.5
alpha-2-macroglobulin like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 190.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
10.1 40.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
9.7 29.0 GO:0071461 cellular response to redox state(GO:0071461)
9.2 46.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
7.7 23.2 GO:0030185 nitric oxide transport(GO:0030185)
7.0 84.2 GO:0006069 ethanol oxidation(GO:0006069)
5.5 22.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
5.2 10.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
4.4 26.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
4.3 12.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
4.1 608.2 GO:0006958 complement activation, classical pathway(GO:0006958)
4.0 16.1 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
4.0 27.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
3.8 26.9 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
3.0 5.9 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
2.9 14.7 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
2.9 11.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
2.9 2.9 GO:0046110 xanthine metabolic process(GO:0046110)
2.9 17.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.8 8.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.7 8.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
2.6 5.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
2.6 7.7 GO:1903487 regulation of lactation(GO:1903487)
2.5 7.5 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.5 7.4 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.4 7.3 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
2.3 7.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.2 6.6 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
2.2 6.5 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
2.1 6.4 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
2.1 6.4 GO:0035026 leading edge cell differentiation(GO:0035026)
2.1 10.6 GO:0035106 operant conditioning(GO:0035106)
2.0 12.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.0 10.2 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
2.0 6.1 GO:0061760 antifungal innate immune response(GO:0061760)
2.0 15.9 GO:0046541 saliva secretion(GO:0046541)
1.9 5.7 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.9 13.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
1.9 22.2 GO:0071285 cellular response to lithium ion(GO:0071285)
1.8 3.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.8 19.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.7 5.1 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
1.7 5.1 GO:0030573 bile acid catabolic process(GO:0030573)
1.7 23.7 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.7 10.0 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
1.6 4.8 GO:0060903 positive regulation of meiosis I(GO:0060903)
1.6 273.7 GO:0002377 immunoglobulin production(GO:0002377)
1.5 7.7 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.5 1.5 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
1.5 4.6 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.4 5.7 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.4 5.7 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
1.4 4.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
1.4 4.1 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
1.4 4.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.4 1.4 GO:0032661 regulation of interleukin-18 production(GO:0032661)
1.4 4.1 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
1.3 7.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.3 3.9 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.3 5.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.3 7.6 GO:0016554 cytidine to uridine editing(GO:0016554)
1.2 7.5 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
1.2 3.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.2 4.9 GO:0046351 sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
1.2 4.9 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
1.2 4.8 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
1.2 8.4 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.2 14.3 GO:0006824 cobalt ion transport(GO:0006824)
1.2 3.6 GO:0019732 antifungal humoral response(GO:0019732)
1.1 2.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
1.1 3.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.1 5.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.1 5.5 GO:1903936 cellular response to sodium arsenite(GO:1903936)
1.0 5.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0 10.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.0 2.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.0 11.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.0 7.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
1.0 4.0 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
1.0 3.0 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.0 5.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.0 4.8 GO:0032074 negative regulation of nuclease activity(GO:0032074)
1.0 3.8 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.9 1.9 GO:0097325 melanocyte proliferation(GO:0097325)
0.9 2.8 GO:0061011 hepatic duct development(GO:0061011)
0.9 2.8 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.9 10.2 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.9 3.7 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.9 5.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.9 3.4 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.8 5.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.8 14.7 GO:0015671 oxygen transport(GO:0015671)
0.8 7.3 GO:0015693 magnesium ion transport(GO:0015693)
0.8 3.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.8 4.7 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.8 8.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.8 5.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.8 15.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.7 2.9 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.7 6.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7 2.9 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.7 10.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.7 48.0 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.7 2.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.7 2.8 GO:0031017 response to chlorate(GO:0010157) exocrine pancreas development(GO:0031017)
0.7 2.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
0.7 3.5 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 4.2 GO:0051026 chiasma assembly(GO:0051026)
0.7 4.8 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.7 3.5 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.7 2.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.7 2.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.7 4.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.7 3.4 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.6 3.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.6 2.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.6 18.1 GO:0098743 cell aggregation(GO:0098743)
0.6 0.6 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.6 2.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6 3.0 GO:0090309 regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.6 1.8 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076) serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.6 58.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.6 3.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.6 7.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.6 2.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.6 2.8 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.6 2.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.5 14.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 3.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.5 8.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.5 4.3 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.5 3.2 GO:0019530 taurine metabolic process(GO:0019530)
0.5 11.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.5 3.1 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.5 3.6 GO:0043615 astrocyte cell migration(GO:0043615)
0.5 7.7 GO:0006600 creatine metabolic process(GO:0006600)
0.5 1.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.5 5.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.5 3.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.5 9.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.5 1.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.5 7.7 GO:0006702 androgen biosynthetic process(GO:0006702)
0.5 3.3 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.5 3.3 GO:0080009 mRNA methylation(GO:0080009)
0.5 8.0 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.5 1.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.5 9.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.5 12.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 2.7 GO:2000483 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
0.4 7.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 2.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.4 3.5 GO:0015747 urate transport(GO:0015747)
0.4 4.7 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.4 0.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.4 3.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 1.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 4.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.4 2.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 4.3 GO:0001675 acrosome assembly(GO:0001675)
0.4 4.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.4 3.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4 23.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.4 2.6 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 12.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.4 5.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.4 13.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 1.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 4.5 GO:0006265 DNA topological change(GO:0006265)
0.3 4.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.3 2.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 2.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3 5.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.3 1.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.3 3.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.3 6.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 1.3 GO:0042574 retinal metabolic process(GO:0042574)
0.3 1.3 GO:0044026 DNA hypermethylation(GO:0044026)
0.3 9.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.3 2.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.3 1.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 17.2 GO:0045576 mast cell activation(GO:0045576)
0.3 1.5 GO:0030070 insulin processing(GO:0030070)
0.3 1.8 GO:0038016 insulin receptor internalization(GO:0038016)
0.3 14.6 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.3 1.5 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 2.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.3 3.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.3 2.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.3 1.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 4.9 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.3 2.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 76.9 GO:0002250 adaptive immune response(GO:0002250)
0.3 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3 8.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.3 1.5 GO:0071865 cell proliferation in bone marrow(GO:0071838) regulation of cell proliferation in bone marrow(GO:0071863) positive regulation of cell proliferation in bone marrow(GO:0071864) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.2 0.5 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 0.5 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.2 8.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 4.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 16.0 GO:0030574 collagen catabolic process(GO:0030574)
0.2 6.7 GO:0007398 ectoderm development(GO:0007398)
0.2 3.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 4.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 0.9 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 2.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 1.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 0.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 0.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.9 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.2 3.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 7.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 1.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.2 5.1 GO:0006825 copper ion transport(GO:0006825)
0.2 2.7 GO:0035878 nail development(GO:0035878)
0.2 6.0 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.2 1.6 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.6 GO:0010649 regulation of cell communication by electrical coupling(GO:0010649)
0.2 1.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 4.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 10.4 GO:0001895 retina homeostasis(GO:0001895)
0.2 0.4 GO:0071316 cellular response to nicotine(GO:0071316) positive regulation of miRNA metabolic process(GO:2000630)
0.2 2.1 GO:0034505 tooth mineralization(GO:0034505)
0.2 14.1 GO:0031295 T cell costimulation(GO:0031295)
0.2 2.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.7 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.2 1.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 1.9 GO:0042737 drug catabolic process(GO:0042737)
0.2 13.8 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.2 0.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 2.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 3.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 1.1 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.2 1.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 3.3 GO:0030449 regulation of complement activation(GO:0030449)
0.2 0.5 GO:0061026 central nervous system morphogenesis(GO:0021551) cardiac muscle tissue regeneration(GO:0061026)
0.2 2.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 6.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 0.3 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 2.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.2 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 3.8 GO:0035456 response to interferon-beta(GO:0035456)
0.1 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 2.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.6 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 1.7 GO:0015871 choline transport(GO:0015871)
0.1 1.0 GO:0046449 creatinine metabolic process(GO:0046449)
0.1 0.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 7.2 GO:0006968 cellular defense response(GO:0006968)
0.1 6.8 GO:0006953 acute-phase response(GO:0006953)
0.1 3.7 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.1 7.4 GO:0006959 humoral immune response(GO:0006959)
0.1 1.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 3.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.5 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 1.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 4.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 11.4 GO:0070268 cornification(GO:0070268)
0.1 7.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 4.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.0 GO:0043691 reverse cholesterol transport(GO:0043691)
0.1 0.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 1.1 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 2.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.0 GO:0014010 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.1 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 14.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.4 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.1 0.4 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.5 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.2 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleoside transmembrane transport(GO:0015860) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.2 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.1 5.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.0 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 2.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 3.2 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 4.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.8 GO:0048240 sperm capacitation(GO:0048240)
0.0 2.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.6 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.2 GO:0071839 apoptotic process in bone marrow(GO:0071839)
0.0 1.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 4.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.7 GO:0030282 bone mineralization(GO:0030282)
0.0 1.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.8 GO:0030220 platelet formation(GO:0030220)
0.0 3.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.7 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.6 GO:0002449 lymphocyte mediated immunity(GO:0002449)
0.0 2.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.8 GO:0060349 bone morphogenesis(GO:0060349)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 190.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
14.0 41.9 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
7.7 30.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
5.6 105.6 GO:0042613 MHC class II protein complex(GO:0042613)
4.8 237.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
2.2 6.5 GO:0097679 other organism cytoplasm(GO:0097679)
1.9 7.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.6 6.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.5 7.4 GO:0005826 actomyosin contractile ring(GO:0005826)
1.3 6.7 GO:0005579 membrane attack complex(GO:0005579)
1.3 17.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.3 5.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.3 6.3 GO:0036398 TCR signalosome(GO:0036398)
1.2 4.8 GO:0071546 pi-body(GO:0071546)
1.2 210.7 GO:0072562 blood microparticle(GO:0072562)
1.2 3.5 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
1.1 9.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.1 20.4 GO:0036038 MKS complex(GO:0036038)
1.1 10.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.0 3.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.9 6.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.9 4.7 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.8 2.4 GO:0032437 cuticular plate(GO:0032437)
0.8 4.9 GO:0005577 fibrinogen complex(GO:0005577)
0.8 15.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.8 13.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.8 8.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.7 5.2 GO:0036021 endolysosome lumen(GO:0036021)
0.7 5.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.7 7.2 GO:0030478 actin cap(GO:0030478)
0.7 26.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.6 1.9 GO:0070195 growth hormone receptor complex(GO:0070195)
0.6 9.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 1.6 GO:0000805 X chromosome(GO:0000805)
0.5 4.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 4.0 GO:0061689 tricellular tight junction(GO:0061689)
0.5 41.9 GO:0035580 specific granule lumen(GO:0035580)
0.5 2.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.4 3.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 3.1 GO:0043196 varicosity(GO:0043196)
0.4 3.9 GO:0030061 mitochondrial crista(GO:0030061)
0.4 3.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.4 6.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 14.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 3.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.4 2.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 2.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.4 33.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 4.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 2.7 GO:1990635 proximal dendrite(GO:1990635)
0.4 26.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 2.2 GO:1990769 proximal neuron projection(GO:1990769)
0.4 7.3 GO:0033270 paranode region of axon(GO:0033270)
0.3 521.0 GO:0005615 extracellular space(GO:0005615)
0.3 3.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 2.3 GO:0060091 kinocilium(GO:0060091)
0.3 13.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 8.1 GO:0042101 T cell receptor complex(GO:0042101)
0.3 4.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 3.3 GO:0016013 syntrophin complex(GO:0016013)
0.3 49.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 6.1 GO:0005581 collagen trimer(GO:0005581)
0.3 10.4 GO:0001533 cornified envelope(GO:0001533)
0.2 3.2 GO:0046930 pore complex(GO:0046930)
0.2 0.9 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 3.5 GO:0035102 PRC1 complex(GO:0035102)
0.2 4.6 GO:0031932 TORC2 complex(GO:0031932)
0.2 3.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 2.0 GO:0061574 ASAP complex(GO:0061574)
0.2 1.6 GO:0070449 elongin complex(GO:0070449)
0.2 2.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 4.0 GO:0032300 mismatch repair complex(GO:0032300)
0.2 6.8 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.1 GO:0042555 MCM complex(GO:0042555)
0.2 3.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 1.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 11.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 5.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 4.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 9.6 GO:0005811 lipid particle(GO:0005811)
0.1 6.0 GO:0005844 polysome(GO:0005844)
0.1 1.1 GO:0032797 SMN complex(GO:0032797)
0.1 0.7 GO:0042611 MHC protein complex(GO:0042611)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 2.7 GO:0045095 keratin filament(GO:0045095)
0.1 10.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.2 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 84.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
7.7 46.0 GO:0003796 lysozyme activity(GO:0003796)
6.1 18.2 GO:0046848 hydroxyapatite binding(GO:0046848)
5.4 27.1 GO:0019862 IgA binding(GO:0019862)
4.4 30.6 GO:0030492 hemoglobin binding(GO:0030492)
4.2 988.4 GO:0003823 antigen binding(GO:0003823)
3.7 18.5 GO:0032395 MHC class II receptor activity(GO:0032395)
3.7 11.0 GO:0035375 zymogen binding(GO:0035375)
3.6 29.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
3.5 10.6 GO:0016497 substance K receptor activity(GO:0016497)
2.9 2.9 GO:0004031 aldehyde oxidase activity(GO:0004031)
2.4 9.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.4 7.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
2.3 9.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.2 184.1 GO:0050840 extracellular matrix binding(GO:0050840)
2.1 6.4 GO:0070052 collagen V binding(GO:0070052)
2.1 6.3 GO:0017129 triglyceride binding(GO:0017129)
1.9 5.7 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.8 12.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.7 8.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.7 22.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.6 13.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.6 14.7 GO:0031685 adenosine receptor binding(GO:0031685)
1.6 4.9 GO:0002113 interleukin-33 binding(GO:0002113)
1.6 1.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.6 16.1 GO:0004064 arylesterase activity(GO:0004064)
1.6 17.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.6 4.7 GO:0042289 MHC class II protein binding(GO:0042289)
1.5 4.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.5 4.4 GO:0004556 alpha-amylase activity(GO:0004556)
1.4 7.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.4 5.7 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.4 14.3 GO:0005549 odorant binding(GO:0005549)
1.4 7.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.4 4.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.4 5.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.4 4.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.4 4.1 GO:0003916 DNA topoisomerase activity(GO:0003916)
1.3 11.4 GO:0004875 complement receptor activity(GO:0004875)
1.2 7.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
1.2 3.7 GO:0008859 exoribonuclease II activity(GO:0008859)
1.2 14.7 GO:0005344 oxygen transporter activity(GO:0005344)
1.2 4.9 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.2 16.1 GO:0031419 cobalamin binding(GO:0031419)
1.1 3.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.1 3.2 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
1.0 4.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.0 2.9 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.9 4.7 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.9 2.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.9 3.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.9 6.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.8 2.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.8 2.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.8 7.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.8 6.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 3.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.8 3.8 GO:0004905 type I interferon receptor activity(GO:0004905)
0.8 2.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 2.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.7 3.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.7 3.7 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.7 3.7 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.7 13.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.7 2.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.7 13.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.6 5.2 GO:0043394 proteoglycan binding(GO:0043394)
0.6 20.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 3.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.6 6.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.6 5.6 GO:0008199 ferric iron binding(GO:0008199)
0.6 14.6 GO:0051018 protein kinase A binding(GO:0051018)
0.6 3.6 GO:0008142 oxysterol binding(GO:0008142)
0.6 28.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.6 5.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 8.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.6 2.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.6 9.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 4.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.6 2.8 GO:0004370 glycerol kinase activity(GO:0004370)
0.6 3.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 4.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.6 1.7 GO:0042806 fucose binding(GO:0042806)
0.5 10.4 GO:0048018 receptor agonist activity(GO:0048018)
0.5 1.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.5 3.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 8.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 3.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.5 6.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.5 1.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5 2.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.5 1.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.5 21.7 GO:0008009 chemokine activity(GO:0008009)
0.5 44.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.5 10.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.5 1.9 GO:0002046 opsin binding(GO:0002046)
0.5 3.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.5 4.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.5 12.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 5.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.5 6.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 7.8 GO:0019825 oxygen binding(GO:0019825)
0.5 5.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.5 2.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.4 3.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.4 5.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 7.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 1.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 9.6 GO:0031005 filamin binding(GO:0031005)
0.4 4.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.4 1.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 7.5 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 1.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.4 1.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.4 3.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 6.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.4 3.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 6.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 1.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 3.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4 8.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 3.8 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4 2.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 4.4 GO:0070330 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.4 5.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 4.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 4.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 1.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 2.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 2.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 2.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 2.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 6.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 2.7 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.3 6.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 0.9 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 7.2 GO:0005523 tropomyosin binding(GO:0005523)
0.3 8.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.3 3.4 GO:0051434 BH3 domain binding(GO:0051434)
0.3 3.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.3 1.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 5.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 2.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 1.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 6.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 0.7 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 3.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 4.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 29.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 7.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 1.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 3.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 2.7 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.2 6.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 5.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 2.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 2.4 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 15.6 GO:0019843 rRNA binding(GO:0019843)
0.2 2.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 1.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 5.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 1.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 2.8 GO:0008301 DNA binding, bending(GO:0008301)
0.2 5.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 0.7 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 1.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 4.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 23.9 GO:0008201 heparin binding(GO:0008201)
0.2 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 4.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.2 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 9.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 11.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 0.5 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 0.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 19.1 GO:0005179 hormone activity(GO:0005179)
0.2 6.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 3.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 2.7 GO:0070402 NADPH binding(GO:0070402)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 3.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 6.2 GO:0032934 sterol binding(GO:0032934)
0.1 1.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 4.3 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 5.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 10.1 GO:0019210 kinase inhibitor activity(GO:0019210)
0.1 2.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.3 GO:1901612 cardiolipin binding(GO:1901612)
0.1 4.1 GO:0004540 ribonuclease activity(GO:0004540)
0.1 3.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 4.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 3.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 8.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 2.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 6.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0015926 glucosidase activity(GO:0015926)
0.1 10.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 3.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 2.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 3.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 3.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 3.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 9.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 1.6 GO:0019838 growth factor binding(GO:0019838)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 209.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.1 8.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.8 3.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.7 31.8 NABA COLLAGENS Genes encoding collagen proteins
0.6 36.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.6 3.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 9.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 9.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 61.1 PID CMYB PATHWAY C-MYB transcription factor network
0.4 3.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 10.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 2.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 1.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 7.7 PID IL27 PATHWAY IL27-mediated signaling events
0.3 8.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 4.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 9.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 58.2 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.3 20.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 3.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 16.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.2 18.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 8.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 6.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 2.7 ST GAQ PATHWAY G alpha q Pathway
0.2 10.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 6.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 7.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 7.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 2.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 7.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 2.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 7.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 3.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 4.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 39.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 7.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 23.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.5 PID SHP2 PATHWAY SHP2 signaling
0.1 2.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 6.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 4.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.7 PID MYC PATHWAY C-MYC pathway
0.1 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 3.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 12.8 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 84.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
7.1 190.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
4.5 94.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.6 6.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.5 18.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.3 60.9 REACTOME AMYLOIDS Genes involved in Amyloids
1.0 16.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.7 16.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.7 5.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.7 15.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.6 9.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.6 55.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.6 8.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.6 9.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.5 12.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 7.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.5 13.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 2.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 38.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 8.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 7.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.4 39.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 7.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.4 8.3 REACTOME DEFENSINS Genes involved in Defensins
0.4 4.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 14.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 6.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 7.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 7.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.3 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 3.5 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.3 18.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 5.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 6.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.3 31.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 5.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.3 1.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.3 4.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 8.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.3 5.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.3 34.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 4.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 2.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.2 3.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 6.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 4.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 2.2 REACTOME OPSINS Genes involved in Opsins
0.2 2.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.7 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.2 3.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 2.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.2 3.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 6.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 29.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 6.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.7 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 2.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 13.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 18.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 7.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 10.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 4.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 2.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 6.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 2.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 2.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 5.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 2.3 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport