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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXN1

Z-value: 4.12

Motif logo

Transcription factors associated with FOXN1

Gene Symbol Gene ID Gene Info
ENSG00000109101.8 FOXN1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXN1hg38_v1_chr17_+_28506320_28506360-0.466.4e-13Click!

Activity profile of FOXN1 motif

Sorted Z-values of FOXN1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_42302690 13.67 ENST00000596265.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr19_-_42302576 13.27 ENST00000262890.8
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr15_+_65869974 13.11 ENST00000567671.1
RAB11A, member RAS oncogene family
chr19_-_42302766 12.64 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr1_-_8878706 11.91 ENST00000646156.1
enolase 1
chr14_+_54397021 10.62 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr1_-_8878646 10.50 ENST00000643438.1
enolase 1
chr12_+_69239592 10.26 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr14_+_54396949 9.86 ENST00000611205.4
cyclin dependent kinase inhibitor 3
chr14_+_54396964 9.75 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr2_+_112645930 9.19 ENST00000272542.8
solute carrier family 20 member 1
chr12_+_51238854 9.18 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr1_-_8878677 9.06 ENST00000234590.10
ENST00000647408.1
enolase 1
chr17_-_64662290 8.89 ENST00000262435.14
SMAD specific E3 ubiquitin protein ligase 2
chr1_-_8879170 8.88 ENST00000489867.2
enolase 1
chr12_-_53677397 8.84 ENST00000338662.6
ENST00000552242.5
ATP synthase membrane subunit c locus 2
chr4_-_102825854 8.68 ENST00000350435.11
ubiquitin conjugating enzyme E2 D3
chr18_+_3448456 8.66 ENST00000549780.5
TGFB induced factor homeobox 1
chr10_+_14838288 8.62 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
novel protein
heat shock protein family A (Hsp70) member 14
chr1_-_53238485 8.15 ENST00000371466.4
ENST00000371470.8
mago homolog, exon junction complex subunit
chr12_+_69239627 7.83 ENST00000551516.1
cleavage and polyadenylation specific factor 6
chr4_-_102825767 7.82 ENST00000505207.5
ENST00000502404.5
ENST00000507845.5
ubiquitin conjugating enzyme E2 D3
chr15_-_90233902 7.80 ENST00000328649.11
ENST00000650306.1
calcium and integrin binding 1
chr12_-_52573816 7.78 ENST00000549343.5
ENST00000305620.3
keratin 74
chr11_-_6683282 7.71 ENST00000532203.1
ENST00000288937.7
mitochondrial ribosomal protein L17
chr14_+_96502358 7.56 ENST00000216277.13
ENST00000557320.5
ENST00000557471.5
poly(A) polymerase alpha
chr4_-_1712250 7.53 ENST00000318386.8
stem-loop binding protein
chr8_+_26291758 7.44 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr2_-_61537740 7.37 ENST00000678081.1
ENST00000676889.1
ENST00000677850.1
ENST00000676789.1
exportin 1
chr15_-_90234046 7.32 ENST00000612800.1
calcium and integrin binding 1
chr11_+_65041203 6.57 ENST00000652489.1
ENST00000674184.1
SAC3 domain containing 1
chr2_+_186486246 6.56 ENST00000337859.11
zinc finger CCCH-type containing 15
chr1_-_241519701 6.52 ENST00000366560.4
ENST00000683521.1
fumarate hydratase
chr1_-_25906457 6.49 ENST00000426559.6
stathmin 1
chr4_-_1712310 6.49 ENST00000488267.5
ENST00000429429.6
ENST00000489418.6
ENST00000480936.1
stem-loop binding protein
chr1_+_43974902 6.40 ENST00000532642.5
ENST00000236067.8
ENST00000471859.6
ENST00000472174.7
ATPase H+ transporting V0 subunit b
chr20_-_62143374 6.28 ENST00000370873.9
ENST00000370858.3
proteasome 20S subunit alpha 7
chr11_+_65040895 6.10 ENST00000531072.1
ENST00000398846.6
SAC3 domain containing 1
chr20_+_31605280 5.97 ENST00000376105.4
ENST00000376112.4
inhibitor of DNA binding 1, HLH protein
chr1_+_181088692 5.96 ENST00000367577.7
immediate early response 5
chr1_+_40979659 5.84 ENST00000650070.2
ENST00000649864.1
ENST00000649124.1
CTP synthase 1
chr3_-_150763093 5.78 ENST00000312960.4
siah E3 ubiquitin protein ligase 2
chr14_+_51989609 5.72 ENST00000556760.5
RNA transcription, translation and transport factor
chr16_-_30429800 5.62 ENST00000568973.5
ENST00000678016.1
ENST00000565758.1
ENST00000319285.5
ENST00000567983.1
dCTP pyrophosphatase 1
chr2_-_61538180 5.47 ENST00000677150.1
ENST00000678182.1
ENST00000677928.1
ENST00000406957.5
exportin 1
chr5_+_154858594 5.44 ENST00000519430.5
ENST00000520671.5
ENST00000521583.5
ENST00000285896.11
ENST00000518028.5
ENST00000519404.5
ENST00000519394.5
ENST00000518775.5
CCR4-NOT transcription complex subunit 8
chrX_+_71283186 5.41 ENST00000535149.5
non-POU domain containing octamer binding
chr20_-_50113139 5.38 ENST00000371657.9
ENST00000371674.8
ENST00000625172.3
ENST00000557021.5
ENST00000617119.4
ubiquitin conjugating enzyme E2 V1
chr10_+_92593112 5.34 ENST00000260731.5
kinesin family member 11
chr15_+_65869535 5.24 ENST00000569896.1
RAB11A, member RAS oncogene family
chr13_-_46387724 5.02 ENST00000675585.1
rubicon like autophagy enhancer
chr8_-_30658176 4.94 ENST00000355904.9
general transcription factor IIE subunit 2
chr14_+_51989508 4.91 ENST00000261700.8
RNA transcription, translation and transport factor
chr22_+_20117497 4.88 ENST00000331821.7
ENST00000411892.5
RAN binding protein 1
chr17_-_48101087 4.88 ENST00000393408.7
chromobox 1
chr12_-_6851245 4.82 ENST00000540683.1
ENST00000229265.10
ENST00000535406.5
ENST00000422785.7
ENST00000538862.7
cell division cycle associated 3
chr14_+_96502542 4.77 ENST00000556619.5
ENST00000392990.6
poly(A) polymerase alpha
chr9_-_128127711 4.76 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
prostaglandin E synthase 2
chr14_+_69611586 4.67 ENST00000342745.5
sushi domain containing 6
chr10_-_121975168 4.66 ENST00000369017.5
ENST00000369023.8
NSE4 homolog A, SMC5-SMC6 complex component
chr5_+_154858218 4.58 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CCR4-NOT transcription complex subunit 8
chr12_+_120496101 4.55 ENST00000550178.1
ENST00000550845.5
ENST00000549989.1
ENST00000552870.1
ENST00000242577.11
dynein light chain LC8-type 1
chr5_+_73498408 4.55 ENST00000335895.12
ENST00000678135.1
ENST00000380591.7
ENST00000677654.1
ENST00000507081.6
basic transcription factor 3
chr17_-_48101379 4.53 ENST00000581003.5
ENST00000225603.9
chromobox 1
chr3_-_133661896 4.51 ENST00000260810.10
DNA topoisomerase II binding protein 1
chr12_+_55716589 4.51 ENST00000549424.1
novel protein
chr16_-_57447366 4.50 ENST00000567751.5
ENST00000568940.5
ENST00000563341.1
ENST00000394391.9
ENST00000565961.5
ENST00000569370.5
ENST00000567518.5
ENST00000565786.5
cytokine induced apoptosis inhibitor 1
chr17_-_78925376 4.33 ENST00000262768.11
TIMP metallopeptidase inhibitor 2
chr5_+_154858482 4.19 ENST00000519211.5
ENST00000522458.5
ENST00000519903.5
ENST00000521450.5
ENST00000403027.6
CCR4-NOT transcription complex subunit 8
chr15_+_65869456 4.17 ENST00000564910.5
ENST00000566233.5
ENST00000565075.5
ENST00000261890.7
RAB11A, member RAS oncogene family
chr1_-_244451896 4.17 ENST00000366535.4
adenylosuccinate synthase 2
chr2_+_27890716 4.12 ENST00000344773.6
ENST00000379624.6
ENST00000342045.6
ENST00000379632.6
ENST00000361704.6
BRISC and BRCA1 A complex member 2
chr5_+_66144288 4.09 ENST00000334121.11
splicing regulatory glutamic acid and lysine rich protein 1
chr2_-_53970985 4.04 ENST00000404125.6
proteasome activator subunit 4
chr12_+_120496075 3.99 ENST00000548214.1
ENST00000392508.2
dynein light chain LC8-type 1
chr12_+_51238724 3.99 ENST00000449723.7
ENST00000549555.5
ENST00000439799.6
ENST00000412716.8
ENST00000425012.6
DAZ associated protein 2
chr10_+_68956158 3.91 ENST00000354185.9
DExD-box helicase 21
chr19_+_33373694 3.90 ENST00000284000.9
CCAAT enhancer binding protein gamma
chr20_+_62642492 3.86 ENST00000217159.6
solute carrier organic anion transporter family member 4A1
chr11_-_67508152 3.80 ENST00000301488.8
cyclin dependent kinase 2 associated protein 2
chr16_+_1153202 3.79 ENST00000358590.8
ENST00000638323.1
calcium voltage-gated channel subunit alpha1 H
chrX_-_16869840 3.67 ENST00000380084.8
RB binding protein 7, chromatin remodeling factor
chr13_-_46387447 3.66 ENST00000676051.1
ENST00000378787.7
ENST00000378781.7
ENST00000378797.6
rubicon like autophagy enhancer
chr6_-_24911029 3.64 ENST00000259698.9
ENST00000644621.1
ENST00000644411.1
RHO family interacting cell polarization regulator 2
chr6_+_29942523 3.64 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr2_+_169799279 3.62 ENST00000409333.1
small RNA binding exonuclease protection factor La
chr18_+_50879056 3.60 ENST00000321341.11
ENST00000638937.1
ENST00000382927.3
ENST00000639850.1
ENST00000638410.1
ENST00000639255.1
ENST00000640965.1
malic enzyme 2
chr3_+_50617119 3.55 ENST00000430409.5
ENST00000621469.5
ENST00000357955.6
MAPK activated protein kinase 3
chr1_-_45686501 3.55 ENST00000355105.8
ENST00000290795.7
GC-rich promoter binding protein 1 like 1
chr12_+_55716463 3.54 ENST00000551926.1
biogenesis of lysosomal organelles complex 1 subunit 1
chr3_-_195442977 3.54 ENST00000326793.11
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr10_+_68956436 3.50 ENST00000620315.1
DExD-box helicase 21
chr22_-_41688799 3.45 ENST00000469028.2
ENST00000463675.6
ENST00000649479.1
ENST00000469522.1
small nuclear ribonucleoprotein 13
chr16_+_30762289 3.38 ENST00000566811.5
ENST00000565995.5
ENST00000563683.5
ENST00000357890.9
ENST00000324685.11
ENST00000565931.1
ring finger protein 40
chr15_-_49155574 3.36 ENST00000558843.5
ENST00000388901.10
ENST00000542928.5
ENST00000561248.1
ENST00000299259.10
COP9 signalosome subunit 2
chr16_+_31033092 3.34 ENST00000394998.5
syntaxin 4
chr4_+_109433772 3.34 ENST00000504968.6
ENST00000399100.6
ENST00000265175.5
SEC24 homolog B, COPII coat complex component
chr10_+_110919595 3.29 ENST00000369452.9
SHOC2 leucine rich repeat scaffold protein
chr19_+_38619082 3.28 ENST00000614624.4
ENST00000593149.5
ENST00000538434.5
ENST00000588934.5
ENST00000248342.9
ENST00000545173.6
ENST00000591409.5
ENST00000592558.1
eukaryotic translation initiation factor 3 subunit K
chr3_-_190120881 3.26 ENST00000319332.10
prolyl 3-hydroxylase 2
chr20_+_3846799 3.24 ENST00000416600.6
ENST00000428216.4
mitochondrial antiviral signaling protein
chr20_-_2664186 3.23 ENST00000474315.5
ENST00000380843.9
ENST00000380851.9
ENST00000613370.1
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chr17_-_41786688 3.21 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr11_+_66593171 3.18 ENST00000533244.6
copper chaperone for superoxide dismutase
chr10_+_21534315 3.18 ENST00000377091.7
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr15_-_83067199 3.16 ENST00000261721.9
BTB domain containing 1
chr19_+_14433284 3.14 ENST00000242783.11
protein kinase N1
chr18_+_80109236 3.08 ENST00000262198.9
ENST00000560752.5
ADNP homeobox 2
chr8_-_73972248 3.08 ENST00000519082.5
elongin C
chr11_+_66593194 3.05 ENST00000310190.8
copper chaperone for superoxide dismutase
chr6_+_30067530 3.05 ENST00000376765.6
ENST00000376763.5
protein phosphatase 1 regulatory inhibitor subunit 11
chr18_+_9913979 3.04 ENST00000400000.7
ENST00000340541.4
VAMP associated protein A
chrX_-_16870325 3.01 ENST00000468092.1
ENST00000404022.5
ENST00000380087.7
RB binding protein 7, chromatin remodeling factor
chr1_+_153634037 3.00 ENST00000368694.8
ENST00000403433.5
chromatin target of PRMT1
chr10_+_21534213 2.92 ENST00000377100.8
ENST00000377072.8
ENST00000307729.12
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr10_-_29736956 2.91 ENST00000674475.1
supervillin
chr9_-_128128102 2.88 ENST00000617202.4
prostaglandin E synthase 2
chrX_+_71283577 2.83 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chr5_+_140639419 2.82 ENST00000513002.5
ENST00000394671.8
transmembrane and coiled-coil domains 6
chr3_+_46979659 2.82 ENST00000450053.8
neurobeachin like 2
chr16_-_57797764 2.80 ENST00000465878.6
ENST00000561524.5
kinesin family member C3
chr9_-_129835232 2.77 ENST00000372447.7
chromosome 9 open reading frame 78
chr13_+_72782116 2.76 ENST00000326291.11
ENST00000617689.4
progesterone immunomodulatory binding factor 1
chr9_+_33025265 2.76 ENST00000330899.5
DnaJ heat shock protein family (Hsp40) member A1
chr12_+_70243412 2.73 ENST00000550160.5
ENST00000551132.5
ENST00000552915.5
ENST00000550641.6
ENST00000229195.8
ENST00000552483.5
CCR4-NOT transcription complex subunit 2
chr17_-_28645108 2.71 ENST00000528896.7
KIAA0100
chr17_+_35587478 2.68 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr12_-_51269949 2.67 ENST00000603864.5
ENST00000605426.5
small cell adhesion glycoprotein
chr3_-_49358340 2.62 ENST00000419783.3
glutathione peroxidase 1
chr1_+_153633982 2.60 ENST00000368690.7
ENST00000614256.4
chromatin target of PRMT1
chr1_+_235328959 2.56 ENST00000643758.1
ENST00000497327.1
tubulin folding cofactor E
geranylgeranyl diphosphate synthase 1
chr1_+_38012706 2.55 ENST00000373014.5
UTP11 small subunit processome component
chr1_-_25906411 2.54 ENST00000455785.7
stathmin 1
chr5_+_123512087 2.52 ENST00000345990.8
casein kinase 1 gamma 3
chr19_-_46717076 2.52 ENST00000601806.5
ENST00000593363.1
ENST00000291281.9
ENST00000598633.1
ENST00000595515.5
ENST00000433867.5
protein kinase D2
chr16_+_31033513 2.51 ENST00000313843.8
syntaxin 4
chr1_+_235327344 2.51 ENST00000488594.5
geranylgeranyl diphosphate synthase 1
chr10_+_21534440 2.50 ENST00000650772.1
ENST00000652497.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr19_-_48993300 2.50 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr9_+_37422673 2.45 ENST00000318158.11
ENST00000607784.1
glyoxylate and hydroxypyruvate reductase
chr6_+_30067190 2.44 ENST00000376772.8
ENST00000376769.6
protein phosphatase 1 regulatory inhibitor subunit 11
chr6_-_24910695 2.44 ENST00000643623.1
ENST00000538035.6
ENST00000647136.1
RHO family interacting cell polarization regulator 2
chr3_-_49358272 2.43 ENST00000419349.2
glutathione peroxidase 1
chr3_-_49358320 2.43 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
glutathione peroxidase 1
chr5_-_83720813 2.41 ENST00000515590.1
ENST00000274341.9
hyaluronan and proteoglycan link protein 1
chr11_-_67508091 2.41 ENST00000531506.1
cyclin dependent kinase 2 associated protein 2
chr1_+_151540299 2.40 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
tuftelin 1
chr10_-_117375407 2.36 ENST00000334464.7
PDZ domain containing 8
chr19_+_7534711 2.35 ENST00000414982.7
ENST00000450331.7
patatin like phospholipase domain containing 6
chr19_-_16660104 2.31 ENST00000593459.5
ENST00000627144.2
ENST00000358726.6
ENST00000487416.7
ENST00000597711.5
novel protein
small integral membrane protein 7
chr16_+_69187125 2.30 ENST00000336278.8
syntrophin beta 2
chr1_-_27914513 2.19 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr19_+_7534242 2.17 ENST00000545201.6
patatin like phospholipase domain containing 6
chr12_-_51270175 2.17 ENST00000604188.1
ENST00000398453.7
small cell adhesion glycoprotein
chr12_+_55716142 2.15 ENST00000547076.5
biogenesis of lysosomal organelles complex 1 subunit 1
chr16_+_57447470 2.12 ENST00000262507.11
ENST00000564655.5
ENST00000567072.5
ENST00000567933.5
ENST00000563166.1
coenzyme Q9
chr16_-_57798008 2.11 ENST00000421376.6
kinesin family member C3
chr15_-_72783685 2.10 ENST00000456471.3
ENST00000311669.12
ADP dependent glucokinase
chr8_+_85177135 2.02 ENST00000416274.7
E2F transcription factor 5
chr11_+_1838970 2.02 ENST00000381911.6
troponin I2, fast skeletal type
chr19_+_35648286 1.99 ENST00000649813.2
cytochrome c oxidase subunit 6B1
chr13_+_72782225 1.95 ENST00000615625.1
progesterone immunomodulatory binding factor 1
chr9_-_33025088 1.93 ENST00000436040.7
aprataxin
chr8_-_73972223 1.90 ENST00000522337.5
elongin C
chr10_+_5684828 1.87 ENST00000328090.9
ENST00000496681.5
transcription activation suppressor family member 2
chr17_-_42980393 1.87 ENST00000409446.8
ENST00000409399.6
ENST00000421990.7
prostaglandin E synthase 3 like
PTGES3L-AARSD1 readthrough
chr19_-_55461597 1.86 ENST00000589080.1
ENST00000425675.7
ENST00000085068.7
isochorismatase domain containing 2
chr5_+_140639494 1.86 ENST00000252100.6
transmembrane and coiled-coil domains 6
chr12_+_70243714 1.85 ENST00000548159.5
ENST00000549750.5
ENST00000551043.5
CCR4-NOT transcription complex subunit 2
chr16_-_30526758 1.81 ENST00000562803.1
zinc finger protein 768
chrX_+_153687918 1.79 ENST00000253122.10
solute carrier family 6 member 8
chr1_-_27914717 1.78 ENST00000373909.7
replication protein A2
chr1_+_214281149 1.76 ENST00000366957.10
SET and MYND domain containing 2
chr15_+_49155750 1.73 ENST00000327171.7
ENST00000560654.5
galactokinase 2
chr14_-_92121902 1.71 ENST00000329559.8
NADH:ubiquinone oxidoreductase subunit B1
chr9_+_111631354 1.70 ENST00000374294.3
DNAJC25-GNG10 readthrough
chr14_-_92121669 1.70 ENST00000605997.6
ENST00000553514.5
ENST00000617122.1
NADH:ubiquinone oxidoreductase subunit B1
chr13_-_46387231 1.67 ENST00000378784.8
ENST00000429979.6
ENST00000631139.2
rubicon like autophagy enhancer
chr8_-_73972106 1.64 ENST00000284811.12
elongin C
chr5_-_135034212 1.63 ENST00000265340.12
paired like homeodomain 1
chr10_+_127907036 1.63 ENST00000254667.8
ENST00000442830.5
protein tyrosine phosphatase receptor type E
chr19_+_38264563 1.61 ENST00000301244.12
ENST00000587090.5
ENST00000454580.7
serine peptidase inhibitor, Kunitz type 2
chr19_+_1266653 1.60 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr1_+_11934651 1.60 ENST00000449038.5
ENST00000196061.5
ENST00000429000.6
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
chr7_+_44748832 1.58 ENST00000309315.9
ENST00000457123.5
zinc finger MIZ-type containing 2
chr19_-_18919348 1.58 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPI coat complex subunit epsilon
chr17_+_35587239 1.57 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr12_-_6607334 1.57 ENST00000645645.1
ENST00000357008.7
ENST00000544484.6
ENST00000544040.7
chromodomain helicase DNA binding protein 4
chr20_-_59032292 1.57 ENST00000395663.1
ENST00000243997.8
ENST00000395659.1
ATP synthase F1 subunit epsilon
chr20_+_325536 1.54 ENST00000342665.5
SRY-box transcription factor 12
chr2_-_27890348 1.53 ENST00000302188.8
ribokinase
chr12_-_6607397 1.44 ENST00000645005.1
ENST00000646806.1
chromodomain helicase DNA binding protein 4
chr9_-_33025052 1.43 ENST00000673248.1
aprataxin
chr12_-_109880421 1.42 ENST00000544393.5
glycolipid transfer protein
chrX_-_133415478 1.42 ENST00000370828.4
glypican 4
chr16_+_2471284 1.41 ENST00000293973.2
netrin 3
chr16_+_1153098 1.40 ENST00000348261.11
calcium voltage-gated channel subunit alpha1 H
chr11_-_65662780 1.37 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA proto-oncogene, NF-kB subunit
chr17_+_11598456 1.37 ENST00000579828.5
ENST00000262442.9
ENST00000454412.6
dynein axonemal heavy chain 9
chr2_-_20051610 1.36 ENST00000175091.5
lysosomal protein transmembrane 4 alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 22.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
3.8 15.1 GO:0007113 endomitotic cell cycle(GO:0007113)
3.7 40.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.5 7.5 GO:1902905 positive regulation of fibril organization(GO:1902905)
2.2 8.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.2 6.5 GO:0006106 fumarate metabolic process(GO:0006106)
2.0 5.9 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
1.6 9.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.6 4.7 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
1.5 4.5 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
1.5 5.8 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.4 16.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.3 6.7 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.2 6.2 GO:2000035 regulation of stem cell division(GO:2000035)
1.2 4.9 GO:0045218 zonula adherens maintenance(GO:0045218)
1.2 6.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
1.2 12.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.1 3.4 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
1.1 5.6 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
1.1 3.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.1 3.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.0 6.2 GO:0015680 intracellular copper ion transport(GO:0015680)
1.0 3.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.9 8.0 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.9 6.9 GO:0060155 platelet dense granule organization(GO:0060155)
0.9 4.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.8 8.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.8 3.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.8 4.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.7 4.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.7 2.0 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.7 4.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.6 3.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.6 3.6 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.6 4.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.5 1.6 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.5 1.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 5.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.5 15.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.5 1.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.5 3.6 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.4 28.8 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.4 3.6 GO:0044351 macropinocytosis(GO:0044351)
0.4 4.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.4 3.4 GO:0000012 single strand break repair(GO:0000012)
0.4 9.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.4 5.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.4 1.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 7.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 3.9 GO:0045078 enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 1.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.4 7.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 5.7 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.4 16.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.3 7.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 1.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.3 3.0 GO:0072553 terminal button organization(GO:0072553)
0.3 2.8 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.3 1.5 GO:0019323 pentose catabolic process(GO:0019323)
0.3 3.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 3.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 2.5 GO:1901727 protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.3 4.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 27.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 1.2 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 3.4 GO:0000338 protein deneddylation(GO:0000338)
0.2 6.4 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.2 7.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.8 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.2 1.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 3.5 GO:0036010 protein localization to endosome(GO:0036010)
0.2 4.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 3.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 12.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 8.9 GO:0006458 'de novo' protein folding(GO:0006458)
0.2 4.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 3.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.0 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 7.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.1 GO:0046836 glycolipid transport(GO:0046836)
0.1 5.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.7 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 7.4 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.8 GO:0008050 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.1 1.8 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.5 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 8.6 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 0.3 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.2 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 28.2 GO:0016042 lipid catabolic process(GO:0016042)
0.1 4.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 6.3 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.1 2.4 GO:0030220 platelet formation(GO:0030220)
0.1 6.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 3.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 2.5 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 2.1 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 5.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 1.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 2.7 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.4 GO:0003341 cilium movement(GO:0003341)
0.0 1.6 GO:0048255 mRNA stabilization(GO:0048255)
0.0 1.2 GO:0071435 potassium ion export(GO:0071435)
0.0 2.6 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 2.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 3.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 1.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.4 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 12.8 GO:0051301 cell division(GO:0051301)
0.0 2.4 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 1.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 40.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
4.5 22.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.7 24.7 GO:0042382 paraspeckles(GO:0042382)
1.8 5.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
1.6 9.4 GO:0001940 male pronucleus(GO:0001940)
1.6 18.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.3 14.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.2 4.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.8 12.8 GO:0005642 annulate lamellae(GO:0005642)
0.8 3.9 GO:0001651 dense fibrillar component(GO:0001651)
0.7 5.9 GO:0000322 storage vacuole(GO:0000322)
0.7 15.1 GO:0032433 filopodium tip(GO:0032433)
0.7 7.7 GO:0070449 elongin complex(GO:0070449)
0.7 3.4 GO:0033503 HULC complex(GO:0033503)
0.6 6.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.6 8.1 GO:0005915 zonula adherens(GO:0005915)
0.6 4.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.6 6.1 GO:0060171 stereocilium membrane(GO:0060171)
0.5 7.0 GO:0097413 Lewy body(GO:0097413)
0.5 6.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 8.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 6.5 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.5 1.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.4 6.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 4.0 GO:0070552 BRISC complex(GO:0070552)
0.4 4.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 2.9 GO:0036449 microtubule minus-end(GO:0036449)
0.3 13.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 4.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 5.6 GO:0000346 transcription export complex(GO:0000346)
0.3 8.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 6.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 7.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 0.8 GO:0008623 CHRAC(GO:0008623)
0.2 4.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.4 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.2 4.3 GO:0036020 endolysosome membrane(GO:0036020)
0.2 7.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 3.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.2 7.8 GO:0045095 keratin filament(GO:0045095)
0.2 0.5 GO:0035517 PR-DUB complex(GO:0035517)
0.2 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 1.0 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 3.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 3.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 2.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 4.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.0 GO:0005861 troponin complex(GO:0005861)
0.1 2.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.8 GO:0044754 autolysosome(GO:0044754)
0.1 2.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 4.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 3.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 9.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.3 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.1 6.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 7.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 16.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.0 3.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 2.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 8.6 GO:0005840 ribosome(GO:0005840)
0.0 2.5 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 19.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.7 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.1 GO:0030496 midbody(GO:0030496)
0.0 4.8 GO:0005874 microtubule(GO:0005874)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 6.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 8.4 GO:0010008 endosome membrane(GO:0010008)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 35.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
5.0 40.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
5.0 15.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
3.5 14.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
1.8 9.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.8 12.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.6 4.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
1.6 7.8 GO:1990254 keratin filament binding(GO:1990254)
1.5 4.6 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
1.5 7.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.5 5.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.5 5.8 GO:0003883 CTP synthase activity(GO:0003883)
1.3 3.9 GO:0034512 box C/D snoRNA binding(GO:0034512)
1.2 6.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
1.1 3.4 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
1.0 9.4 GO:1990226 histone methyltransferase binding(GO:1990226)
1.0 5.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.9 14.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.9 4.5 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.9 22.5 GO:0031489 myosin V binding(GO:0031489)
0.9 12.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.8 7.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.8 3.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.8 3.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.8 3.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.7 3.6 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.7 5.6 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.7 5.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.6 4.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.6 1.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.5 4.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.5 3.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 9.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.4 25.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4 3.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4 1.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.4 9.7 GO:0070628 proteasome binding(GO:0070628)
0.4 16.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 2.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.0 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.3 10.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 2.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 8.7 GO:0070410 co-SMAD binding(GO:0070410)
0.3 3.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 7.4 GO:0048156 tau protein binding(GO:0048156)
0.3 1.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.3 3.2 GO:0050700 CARD domain binding(GO:0050700)
0.3 5.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 4.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.3 4.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 2.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 2.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 6.4 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 7.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 6.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 4.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 4.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 11.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 4.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 2.8 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.2 8.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 4.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 2.0 GO:0031014 troponin T binding(GO:0031014)
0.1 2.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 3.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.7 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 3.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.5 GO:0070051 fibrinogen binding(GO:0070051)
0.1 3.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.6 GO:0030297 ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 3.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 7.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 1.8 GO:0051184 cofactor transporter activity(GO:0051184)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 13.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 3.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 7.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 35.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 21.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.7 13.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 30.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.4 36.8 PID NOTCH PATHWAY Notch signaling pathway
0.2 6.0 PID ALK1 PATHWAY ALK1 signaling events
0.2 8.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 6.2 PID IL1 PATHWAY IL1-mediated signaling events
0.2 7.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 16.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 3.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 9.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 7.6 PID IFNG PATHWAY IFN-gamma pathway
0.1 3.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 5.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 4.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 9.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 14.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.7 40.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.6 25.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 18.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.5 8.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.5 7.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 16.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 12.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 3.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 7.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 6.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 4.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 19.0 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 6.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 5.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 11.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 2.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 3.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 6.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 7.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 1.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 3.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 4.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 3.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 6.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 10.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.2 3.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 4.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 4.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 5.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 3.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 2.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 10.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 2.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 3.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 4.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing