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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FUBP1

Z-value: 2.67

Motif logo

Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
ENSG00000162613.17 FUBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg38_v1_chr1_-_77979054_77979116-0.252.1e-04Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_91182652 13.57 ENST00000552145.5
ENST00000546745.5
decorin
chr12_-_91182784 12.90 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr5_+_40909490 11.41 ENST00000313164.10
complement C7
chr11_+_114060204 6.25 ENST00000683318.1
zinc finger and BTB domain containing 16
chr6_+_121435595 6.15 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr17_+_39927724 6.13 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr10_+_61901678 5.92 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr9_-_107489754 5.85 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr11_-_10568650 5.28 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr18_-_55588535 4.83 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr17_-_64390852 4.47 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr11_-_10568571 4.22 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_243843164 4.15 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT serine/threonine kinase 3
chr1_+_202348687 3.87 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr3_-_187736493 3.85 ENST00000232014.8
BCL6 transcription repressor
chr4_-_16898619 3.66 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LIM domain binding 2
chr7_+_116526277 3.49 ENST00000393468.1
ENST00000393467.1
caveolin 1
chr16_+_67347358 3.43 ENST00000563189.5
leucine rich repeat containing 36
chr1_+_43300971 3.34 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr11_+_75562274 3.31 ENST00000532356.5
ENST00000524558.5
serpin family H member 1
chr12_-_110920568 3.22 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr18_-_55588184 3.12 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr1_-_27374816 3.10 ENST00000270879.9
ENST00000354982.2
ficolin 3
chr2_+_33134620 3.04 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr2_+_33134579 3.02 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr14_+_61187544 2.99 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr2_+_147844601 2.97 ENST00000404590.1
activin A receptor type 2A
chr2_+_66435558 2.93 ENST00000488550.5
Meis homeobox 1
chr1_+_176463164 2.93 ENST00000367661.7
ENST00000367662.5
pappalysin 2
chr2_+_147844488 2.86 ENST00000535787.5
activin A receptor type 2A
chrX_-_66040072 2.86 ENST00000374737.9
V-set and immunoglobulin domain containing 4
chr12_+_53973108 2.81 ENST00000546378.1
ENST00000243082.4
homeobox C11
chrX_-_66040107 2.76 ENST00000455586.6
V-set and immunoglobulin domain containing 4
chrX_-_66040057 2.75 ENST00000412866.2
V-set and immunoglobulin domain containing 4
chr11_+_75562242 2.74 ENST00000526397.5
ENST00000529643.1
ENST00000525492.5
ENST00000530284.5
ENST00000358171.8
serpin family H member 1
chr9_-_121050264 2.74 ENST00000223642.3
complement C5
chr4_-_16898561 2.72 ENST00000515064.5
ENST00000441778.6
LIM domain binding 2
chr10_-_68332914 2.59 ENST00000358769.7
ENST00000495025.2
phenazine biosynthesis like protein domain containing
chr4_-_88823165 2.53 ENST00000508369.5
family with sequence similarity 13 member A
chr18_-_28177016 2.39 ENST00000430882.6
cadherin 2
chrX_-_54994022 2.34 ENST00000614686.1
ENST00000374992.6
ENST00000375006.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr13_+_36432487 2.30 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr1_+_162069674 2.24 ENST00000361897.10
nitric oxide synthase 1 adaptor protein
chr19_-_19192122 2.24 ENST00000444486.7
ENST00000514819.7
ENST00000585679.1
ENST00000462790.8
myocyte enhancer factor 2B
BORCS8-MEF2B readthrough
BLOC-1 related complex subunit 8
chr12_-_8650529 2.19 ENST00000543467.5
microfibril associated protein 5
chr12_+_10212867 2.18 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr15_-_29822418 2.12 ENST00000614355.5
ENST00000495972.6
ENST00000346128.10
tight junction protein 1
chr4_+_88523810 2.09 ENST00000512194.2
ENST00000598772.1
ENST00000597259.2
HECT and RLD domain containing E3 ubiquitin protein ligase 3
PIGY divergent transcript
chr3_-_51499950 2.05 ENST00000423656.5
ENST00000504652.5
ENST00000684031.1
DDB1 and CUL4 associated factor 1
chr19_+_49363074 1.99 ENST00000597873.5
dickkopf like acrosomal protein 1
chr13_+_49110309 1.93 ENST00000398316.7
fibronectin type III domain containing 3A
chr1_+_162069768 1.93 ENST00000530878.5
nitric oxide synthase 1 adaptor protein
chr4_-_88231322 1.89 ENST00000515655.5
ATP binding cassette subfamily G member 2 (Junior blood group)
chr12_+_14419136 1.84 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
activating transcription factor 7 interacting protein
chr7_+_80638510 1.82 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr11_-_33869816 1.80 ENST00000395833.7
LIM domain only 2
chr17_-_10518536 1.79 ENST00000226207.6
myosin heavy chain 1
chr3_+_29281552 1.76 ENST00000452462.5
ENST00000456853.1
RNA binding motif single stranded interacting protein 3
chr16_+_28553908 1.74 ENST00000317058.8
SAGA complex associated factor 29
chr7_+_75092573 1.74 ENST00000651028.1
ENST00000472837.7
ENST00000629105.2
ENST00000619142.4
ENST00000614064.4
GTF2I repeat domain containing 2B
chr2_-_182427014 1.73 ENST00000409365.5
ENST00000351439.9
phosphodiesterase 1A
chr19_-_44304968 1.71 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
zinc finger protein 235
chr22_-_29553691 1.69 ENST00000490103.6
ENST00000397873.6
THO complex 5
chr12_+_18262730 1.63 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr8_+_84183534 1.59 ENST00000518566.5
RALY RNA binding protein like
chr7_+_138076453 1.59 ENST00000242375.8
ENST00000411726.6
aldo-keto reductase family 1 member D1
chr11_+_1853049 1.54 ENST00000311604.8
lymphocyte specific protein 1
chr8_+_101492423 1.51 ENST00000521085.1
ENST00000646743.1
grainyhead like transcription factor 2
chr4_-_118836067 1.47 ENST00000280551.11
SEC24 homolog D, COPII coat complex component
chr1_+_15456727 1.45 ENST00000359621.5
chymotrypsin like elastase 2A
chr5_+_137889469 1.44 ENST00000290431.5
polycystin 2 like 2, transient receptor potential cation channel
chr14_+_69191760 1.38 ENST00000409949.5
ENST00000312994.9
ENST00000409242.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr1_+_43389889 1.33 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr2_-_151261839 1.32 ENST00000331426.6
RNA binding motif protein 43
chr1_+_156061142 1.30 ENST00000361084.10
RAB25, member RAS oncogene family
chr4_-_54064586 1.29 ENST00000263921.8
cysteine rich hydrophobic domain 2
chr6_-_119149124 1.28 ENST00000368475.8
family with sequence similarity 184 member A
chr3_+_148827800 1.28 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr19_+_18571730 1.24 ENST00000596304.5
ENST00000430157.6
ENST00000596273.5
ENST00000442744.7
ENST00000595683.5
ENST00000599256.5
ENST00000595158.5
ENST00000598780.5
ubiquitin A-52 residue ribosomal protein fusion product 1
chr9_-_110999458 1.23 ENST00000374430.6
lysophosphatidic acid receptor 1
chrX_-_33128360 1.22 ENST00000378677.6
dystrophin
chr14_-_24242600 1.21 ENST00000646753.1
ENST00000558566.1
ENST00000267415.12
ENST00000559019.1
ENST00000399423.8
ENST00000626689.2
TERF1 interacting nuclear factor 2
chr4_+_47485268 1.20 ENST00000273859.8
ENST00000504445.1
ATPase phospholipid transporting 10D (putative)
chr1_-_216805367 1.19 ENST00000360012.7
estrogen related receptor gamma
chr7_+_97005538 1.19 ENST00000518156.3
distal-less homeobox 6
chr7_+_106865263 1.18 ENST00000440650.6
ENST00000496166.6
ENST00000473541.5
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr3_-_170586056 1.11 ENST00000231706.6
solute carrier family 7 member 14
chr6_+_106087580 1.05 ENST00000424894.1
ENST00000648754.1
PR/SET domain 1
chr5_+_93583212 1.03 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr12_+_120302316 1.03 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr14_+_65411845 1.02 ENST00000556518.5
ENST00000557164.5
fucosyltransferase 8
chr5_+_137889437 0.97 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
polycystin 2 like 2, transient receptor potential cation channel
chr11_-_107719657 0.95 ENST00000525934.1
ENST00000531293.1
sarcolipin
chr6_-_56642788 0.89 ENST00000439203.5
ENST00000518935.5
ENST00000370765.11
ENST00000244364.10
dystonin
chr18_-_28036585 0.89 ENST00000399380.7
cadherin 2
chr13_-_26221703 0.84 ENST00000381570.7
ENST00000346166.7
ring finger protein 6
chr5_-_116536458 0.84 ENST00000510263.5
semaphorin 6A
chr19_+_15944299 0.81 ENST00000641275.1
olfactory receptor family 10 subfamily H member 4
chr5_+_55024250 0.80 ENST00000231009.3
granzyme K
chr4_-_100517991 0.79 ENST00000511970.5
ENST00000502569.1
ENST00000305864.7
ENST00000296420.9
endomucin
chr3_+_98147479 0.77 ENST00000641380.1
olfactory receptor family 5 subfamily H member 14
chr6_+_167111789 0.75 ENST00000400926.5
C-C motif chemokine receptor 6
chr1_+_65147830 0.74 ENST00000395334.6
adenylate kinase 4
chr2_+_201116143 0.71 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr8_-_20183090 0.71 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr16_+_19211157 0.70 ENST00000568433.1
synaptotagmin 17
chr2_-_72147819 0.69 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr7_+_106865474 0.68 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr11_+_99021066 0.67 ENST00000527185.5
ENST00000528682.5
contactin 5
chr1_-_44674402 0.65 ENST00000420706.1
ENST00000372235.7
ENST00000372242.7
ENST00000372243.7
ENST00000372244.3
ENST00000372237.8
transmembrane protein 53
chr18_-_63318674 0.64 ENST00000589955.2
BCL2 apoptosis regulator
chr10_-_104085847 0.62 ENST00000648076.2
collagen type XVII alpha 1 chain
chr20_+_21125981 0.62 ENST00000619574.4
kizuna centrosomal protein
chr2_+_147845020 0.61 ENST00000241416.12
activin A receptor type 2A
chr20_-_17558811 0.61 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr15_-_55365231 0.59 ENST00000568543.1
cell cycle progression 1
chr15_-_89221558 0.58 ENST00000268125.10
retinaldehyde binding protein 1
chr17_-_35063648 0.57 ENST00000394597.7
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr11_+_99020940 0.57 ENST00000524871.6
contactin 5
chr4_-_48080172 0.57 ENST00000507351.1
TXK tyrosine kinase
chr17_-_8248035 0.51 ENST00000651323.1
CST telomere replication complex component 1
chr12_-_91058016 0.50 ENST00000266719.4
keratocan
chrX_+_38352573 0.49 ENST00000039007.5
ornithine transcarbamylase
chr21_-_36079382 0.48 ENST00000399201.5
SET domain containing 4
chr19_-_45493208 0.47 ENST00000430715.6
reticulon 2
chr12_+_25958891 0.47 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
Ras association domain family member 8
chr9_-_27005659 0.44 ENST00000380055.6
leucine rich repeat containing 19
chr17_-_43661915 0.42 ENST00000318579.9
ENST00000393661.2
mesenchyme homeobox 1
chr20_+_21126074 0.42 ENST00000619189.5
kizuna centrosomal protein
chr1_-_150765735 0.40 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr7_+_80638633 0.37 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr11_-_62984690 0.37 ENST00000421062.2
ENST00000458333.6
solute carrier family 22 member 6
chr1_+_218346235 0.36 ENST00000366929.4
transforming growth factor beta 2
chr11_+_57763820 0.36 ENST00000674106.1
catenin delta 1
chr5_-_88883199 0.34 ENST00000514015.5
ENST00000503075.1
myocyte enhancer factor 2C
chr3_+_40100007 0.34 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr18_+_7754959 0.34 ENST00000400053.8
protein tyrosine phosphatase receptor type M
chr17_-_78717018 0.33 ENST00000585509.5
cytohesin 1
chr1_-_184037695 0.32 ENST00000361927.9
ENST00000649786.1
collagen beta(1-O)galactosyltransferase 2
chr7_-_108130349 0.30 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chr12_-_9869345 0.28 ENST00000228438.3
C-type lectin domain family 2 member B
chr9_-_127877665 0.25 ENST00000644144.2
adenylate kinase 1
chr1_-_155301423 0.22 ENST00000342741.6
pyruvate kinase L/R
chr1_+_65147514 0.22 ENST00000545314.5
adenylate kinase 4
chr2_-_165203870 0.22 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr13_+_48976597 0.21 ENST00000541916.5
fibronectin type III domain containing 3A
chr6_+_125203639 0.20 ENST00000392482.6
TPD52 like 1
chr5_+_76403266 0.18 ENST00000274364.11
IQ motif containing GTPase activating protein 2
chr11_-_62984957 0.16 ENST00000377871.7
ENST00000360421.9
solute carrier family 22 member 6
chr4_-_25863537 0.16 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr6_+_32164586 0.16 ENST00000333845.11
ENST00000395512.5
ENST00000432129.1
EGF like domain multiple 8
chr8_-_42377227 0.16 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr22_-_46263338 0.15 ENST00000253255.7
polycystin family receptor for egg jelly
chr1_+_88684222 0.15 ENST00000316005.11
ENST00000370521.8
protein kinase N2
chr8_+_74320613 0.14 ENST00000675821.1
ganglioside induced differentiation associated protein 1
chr12_-_21941300 0.13 ENST00000684084.1
ATP binding cassette subfamily C member 9
chr17_+_9021501 0.13 ENST00000173229.7
netrin 1
chr4_+_81030700 0.13 ENST00000282701.4
bone morphogenetic protein 3
chr11_-_790062 0.12 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr17_-_3691887 0.12 ENST00000552050.5
purinergic receptor P2X 5
chr22_-_36703723 0.09 ENST00000300105.7
calcium voltage-gated channel auxiliary subunit gamma 2
chr1_-_161238223 0.09 ENST00000515452.1
nuclear receptor subfamily 1 group I member 3
chr6_-_27867581 0.06 ENST00000331442.5
H1.5 linker histone, cluster member
chrX_+_12906639 0.04 ENST00000311912.5
toll like receptor 8
chr19_+_1438351 0.02 ENST00000233609.8
ribosomal protein S15
chr20_-_14337602 0.01 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 26.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.9 5.8 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
1.5 6.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.1 4.5 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
1.1 22.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.0 4.2 GO:2000170 positive regulation of actin filament-based movement(GO:1903116) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.0 6.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
1.0 3.9 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.9 6.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.9 3.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.9 6.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.9 6.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.9 2.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 3.0 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.5 1.6 GO:0030573 bile acid catabolic process(GO:0030573)
0.5 1.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 2.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4 2.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.4 2.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.4 3.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 3.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.4 1.1 GO:0051136 regulation of extrathymic T cell differentiation(GO:0033082) regulation of NK T cell differentiation(GO:0051136) sebum secreting cell proliferation(GO:1990654)
0.3 1.7 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 1.0 GO:0036071 N-glycan fucosylation(GO:0036071)
0.3 1.0 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.3 1.9 GO:0032252 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.3 1.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.3 9.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 3.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.3 1.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 0.8 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 1.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 4.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 2.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.9 GO:0015886 heme transport(GO:0015886)
0.2 0.7 GO:0098528 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 6.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 2.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 0.8 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 0.5 GO:0097272 ammonia homeostasis(GO:0097272)
0.2 0.6 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 0.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.4 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 5.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.4 GO:0042704 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.5 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 2.3 GO:0007141 male meiosis I(GO:0007141)
0.1 1.2 GO:0017085 response to insecticide(GO:0017085)
0.1 1.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.1 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 3.3 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.3 GO:0031268 pseudopodium organization(GO:0031268)
0.1 0.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.6 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.0 1.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 9.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 1.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 2.9 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0033564 Cdc42 protein signal transduction(GO:0032488) anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 1.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 3.9 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.5 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) hematopoietic stem cell proliferation(GO:0071425)
0.0 1.2 GO:0060021 palate development(GO:0060021)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 1.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.4 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 26.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.8 14.1 GO:0005579 membrane attack complex(GO:0005579)
1.1 6.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.8 4.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.6 1.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.6 2.3 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.4 8.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.4 9.4 GO:0005916 fascia adherens(GO:0005916)
0.2 3.2 GO:0097512 cardiac myofibril(GO:0097512)
0.2 3.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 5.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 1.3 GO:1990130 Iml1 complex(GO:1990130)
0.2 6.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.2 GO:0070187 telosome(GO:0070187)
0.1 0.5 GO:1990879 CST complex(GO:1990879)
0.1 1.2 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.7 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.5 GO:0014802 terminal cisterna(GO:0014802)
0.1 2.1 GO:0005921 gap junction(GO:0005921)
0.1 5.6 GO:0031672 A band(GO:0031672)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 3.9 GO:0005657 replication fork(GO:0005657)
0.1 8.0 GO:0032993 protein-DNA complex(GO:0032993)
0.1 6.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0046930 pore complex(GO:0046930)
0.0 1.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 13.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0050436 microfibril binding(GO:0050436)
1.2 5.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.0 6.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.9 3.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.8 6.4 GO:0098821 BMP receptor activity(GO:0098821)
0.7 6.4 GO:0030274 LIM domain binding(GO:0030274)
0.6 2.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 1.6 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.5 6.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 3.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 8.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 3.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 1.0 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 5.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 26.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 2.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.0 GO:0047708 biotinidase activity(GO:0047708)
0.3 9.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 3.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 3.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 2.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 4.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 6.0 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.8 GO:0005549 odorant binding(GO:0005549)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 2.7 GO:0008009 chemokine activity(GO:0008009)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 3.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 4.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 5.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 8.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 2.2 GO:0000149 SNARE binding(GO:0000149)
0.0 3.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 26.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 9.9 PID ALK1 PATHWAY ALK1 signaling events
0.2 13.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 4.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 14.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.9 PID FOXO PATHWAY FoxO family signaling
0.1 1.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 8.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 10.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 5.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 26.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 9.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 6.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 14.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 5.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 4.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 6.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 10.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 6.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 3.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type