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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GAGGUAG

Z-value: 8.29

Motif logo

miRNA associated with seed GAGGUAG

NamemiRBASE accession
MIMAT0000062
MIMAT0000063
MIMAT0000064
MIMAT0000065
MIMAT0000066
MIMAT0000067
MIMAT0000414
MIMAT0000415
MIMAT0018980
MIMAT0019036
MIMAT0000096

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_204411804 67.79 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr18_+_24113341 57.43 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr12_+_56468561 53.29 ENST00000338146.7
SPRY domain containing 4
chr5_-_131796921 51.05 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr13_-_30307539 49.78 ENST00000380615.8
katanin catalytic subunit A1 like 1
chr18_-_61892997 40.42 ENST00000312828.4
ring finger protein 152
chr7_+_94394886 33.82 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr17_+_18315273 33.36 ENST00000406438.5
SMCR8-C9orf72 complex subunit
chr19_+_56404314 32.43 ENST00000333201.13
ENST00000391778.3
zinc finger protein 583
chrX_-_119943732 32.05 ENST00000371410.5
NFKB activating protein
chrX_-_54357993 31.97 ENST00000375169.7
ENST00000354646.6
WNK lysine deficient protein kinase 3
chr11_+_114059702 30.93 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
zinc finger and BTB domain containing 16
chr15_+_45587366 24.84 ENST00000220531.9
biogenesis of lysosomal organelles complex 1 subunit 6
chr7_-_44885446 24.80 ENST00000395699.5
purine rich element binding protein B
chr15_+_74541200 23.76 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr12_-_42144823 23.46 ENST00000398675.8
glucoside xylosyltransferase 1
chr5_-_172771187 22.84 ENST00000239223.4
dual specificity phosphatase 1
chr9_+_98943898 22.72 ENST00000375001.8
collagen type XV alpha 1 chain
chr6_+_70413462 22.69 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
family with sequence similarity 135 member A
chr7_+_139231225 22.60 ENST00000473989.8
ubinuclein 2
chr16_+_66880503 22.60 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr10_-_73811583 21.59 ENST00000309979.11
N-deacetylase and N-sulfotransferase 2
chr2_+_73984902 21.51 ENST00000409262.8
tet methylcytosine dioxygenase 3
chr2_+_188974364 21.36 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr14_-_74084393 21.12 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr11_+_119206298 21.08 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
Cbl proto-oncogene
chr3_-_57693045 20.99 ENST00000311128.10
DENN domain containing 6A
chr13_+_51584435 20.62 ENST00000612477.1
ENST00000298125.7
WD repeat and FYVE domain containing 2
chr18_+_46334007 20.20 ENST00000269439.12
ENST00000590330.1
ring finger protein 165
chr8_+_24914942 20.13 ENST00000433454.3
neurofilament medium
chr9_-_124771304 19.64 ENST00000416460.6
ENST00000487099.7
nuclear receptor subfamily 6 group A member 1
chr4_+_82900679 19.63 ENST00000302236.10
THAP domain containing 9
chr3_-_170586056 19.47 ENST00000231706.6
solute carrier family 7 member 14
chr5_-_140564550 19.39 ENST00000357560.9
ENST00000358580.9
amyloid beta precursor protein binding family B member 3
chr20_-_49915509 19.37 ENST00000289431.10
spermatogenesis associated 2
chr2_-_206086057 19.26 ENST00000403263.6
INO80 complex subunit D
chr2_+_69915100 19.13 ENST00000264444.7
MAX dimerization protein 1
chr18_-_76495191 19.10 ENST00000443185.7
zinc finger protein 516
chr1_+_59814939 18.98 ENST00000371208.5
hook microtubule tethering protein 1
chr1_-_207051202 18.97 ENST00000315927.9
YOD1 deubiquitinase
chr19_+_1753499 18.48 ENST00000382349.5
one cut homeobox 3
chr4_+_127632926 18.17 ENST00000335251.11
inturned planar cell polarity protein
chr2_+_15940537 17.99 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr1_+_203305510 17.89 ENST00000290551.5
BTG anti-proliferation factor 2
chr11_+_45847406 17.72 ENST00000443527.6
ENST00000616623.4
ENST00000616080.2
cryptochrome circadian regulator 2
chr6_+_57090069 17.65 ENST00000370708.8
ENST00000370702.5
zinc finger protein 451
chr7_-_123748902 17.58 ENST00000223023.5
WASP like actin nucleation promoting factor
chr7_+_108569832 17.41 ENST00000249356.4
DnaJ heat shock protein family (Hsp40) member B9
chr19_+_4007714 17.29 ENST00000262971.3
protein inhibitor of activated STAT 4
chr12_-_92929236 17.25 ENST00000322349.13
early endosome antigen 1
chr1_-_91886144 17.17 ENST00000212355.9
transforming growth factor beta receptor 3
chr2_+_128091166 17.13 ENST00000259253.11
UDP-glucose glycoprotein glucosyltransferase 1
chr11_-_86955385 16.99 ENST00000531380.2
frizzled class receptor 4
chr16_+_70114306 16.83 ENST00000288050.9
ENST00000398122.7
ENST00000568530.5
pyruvate dehydrogenase phosphatase regulatory subunit
chr15_-_51338575 16.73 ENST00000557858.5
ENST00000558328.5
ENST00000396402.6
ENST00000396404.8
ENST00000561075.5
ENST00000405011.6
ENST00000559980.5
ENST00000453807.6
cytochrome P450 family 19 subfamily A member 1
chr3_-_185498964 16.65 ENST00000296254.3
transmembrane protein 41A
chr4_-_173530219 16.60 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr4_-_18021727 16.34 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr12_+_119593758 16.03 ENST00000426426.3
transmembrane protein 233
chr10_+_14878848 15.95 ENST00000433779.5
ENST00000378325.7
ENST00000354919.11
ENST00000313519.9
ENST00000420416.1
suppressor of variegation 3-9 homolog 2
chr17_-_4263847 15.92 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr1_+_19312296 15.88 ENST00000375155.7
ENST00000375153.8
solute carrier family 66 member 1
chr14_+_57390544 15.86 ENST00000555166.5
ENST00000556492.6
ENST00000554703.1
N-alpha-acetyltransferase 30, NatC catalytic subunit
chr22_-_23751080 15.86 ENST00000341976.5
zinc finger protein 70
chr20_+_58692767 15.59 ENST00000356091.11
aminopeptidase like 1
chr20_+_50731571 15.55 ENST00000371610.7
par-6 family cell polarity regulator beta
chr3_+_57556244 15.48 ENST00000311180.9
ENST00000487257.1
phosphodiesterase 12
chr8_+_22245125 15.27 ENST00000306433.9
ENST00000519237.5
ENST00000397802.8
RNA polymerase III subunit D
chr5_-_160312524 15.09 ENST00000520748.1
ENST00000257536.13
ENST00000393977.7
cyclin J like
chr6_+_41638438 15.05 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr9_+_112486819 14.90 ENST00000337530.11
KIAA1958
chr8_-_47738153 14.89 ENST00000408965.4
CCAAT enhancer binding protein delta
chr19_+_46297032 14.82 ENST00000377670.9
hypoxia inducible factor 3 subunit alpha
chr12_+_63844663 14.70 ENST00000355086.8
SLIT-ROBO Rho GTPase activating protein 1
chr1_-_157138388 14.66 ENST00000368192.9
ETS variant transcription factor 3
chr4_+_74933095 14.49 ENST00000513238.5
prostate androgen-regulated mucin-like protein 1
chr7_-_6272575 14.33 ENST00000350796.8
cytohesin 3
chr12_+_69470349 14.31 ENST00000547219.5
ENST00000550316.5
ENST00000548154.5
ENST00000547414.5
ENST00000549921.6
ENST00000550389.5
ENST00000550937.5
ENST00000549092.5
ENST00000550169.5
fibroblast growth factor receptor substrate 2
chr1_-_153390976 14.31 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr9_+_96450115 14.26 ENST00000375249.5
ENST00000375251.7
hyaluronan binding protein 4
chr5_+_65722190 14.03 ENST00000380985.10
ENST00000502464.5
neurolysin
chr9_-_70414657 13.78 ENST00000377126.4
Kruppel like factor 9
chr1_+_40783776 13.74 ENST00000347132.10
potassium voltage-gated channel subfamily Q member 4
chr1_-_182604379 13.72 ENST00000367558.6
regulator of G protein signaling 16
chr1_+_113073162 13.70 ENST00000361127.6
leucine rich repeats and immunoglobulin like domains 2
chr2_+_176188658 13.64 ENST00000331462.6
homeobox D1
chrX_+_16786421 13.57 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr5_+_132658165 13.50 ENST00000617259.2
ENST00000304506.7
interleukin 13
chr16_+_590056 13.29 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C, member RAS oncogene family
chr21_-_26845402 13.17 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_+_87650277 13.16 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr1_-_9129085 13.11 ENST00000377411.5
G protein-coupled receptor 157
chr22_+_29073024 13.09 ENST00000400335.9
kringle containing transmembrane protein 1
chr1_-_204151884 13.04 ENST00000367201.7
ethanolamine kinase 2
chr7_+_20330893 13.03 ENST00000222573.5
integrin subunit beta 8
chr5_+_56815534 13.02 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr14_-_75126964 12.98 ENST00000678037.1
ENST00000553823.6
ENST00000678531.1
ENST00000238616.10
NIMA related kinase 9
chr5_+_157743703 12.94 ENST00000286307.6
LSM11, U7 small nuclear RNA associated
chr3_+_196867856 12.82 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SUMO specific peptidase 5
chr19_+_45079195 12.79 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr11_-_10568650 12.73 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_79947541 12.73 ENST00000369816.5
ELOVL fatty acid elongase 4
chr17_+_66964638 12.72 ENST00000262138.4
calcium voltage-gated channel auxiliary subunit gamma 4
chr3_+_49554436 12.72 ENST00000296452.5
bassoon presynaptic cytomatrix protein
chr17_+_8310220 12.55 ENST00000583529.1
ENST00000361926.8
Rho guanine nucleotide exchange factor 15
chr6_+_106098933 12.54 ENST00000369089.3
PR/SET domain 1
chrX_+_21839599 12.52 ENST00000379484.10
membrane bound transcription factor peptidase, site 2
chr5_-_154478218 12.32 ENST00000231121.3
heart and neural crest derivatives expressed 1
chr5_-_133612524 12.05 ENST00000265342.12
follistatin like 4
chr11_-_12009082 11.97 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr10_+_114043858 11.94 ENST00000369295.4
adrenoceptor beta 1
chr11_-_78188588 11.93 ENST00000526208.5
ENST00000529350.1
ENST00000530018.5
ENST00000528776.1
ENST00000340067.4
potassium channel tetramerization domain containing 21
chr17_-_7294592 11.92 ENST00000007699.10
Y-box binding protein 2
chr15_-_45378519 11.92 ENST00000558163.1
ENST00000396659.8
ENST00000675323.1
ENST00000558336.5
glycine amidinotransferase
chr14_-_100569780 11.92 ENST00000355173.7
brain enriched guanylate kinase associated
chr14_+_24398986 11.77 ENST00000382554.4
NYN domain and retroviral integrase containing
chr1_-_115338231 11.76 ENST00000369512.3
ENST00000680116.1
ENST00000681124.1
ENST00000675637.2
ENST00000676038.2
nerve growth factor
chr9_-_16870662 11.73 ENST00000380672.9
basonuclin 2
chrX_+_118974608 11.70 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr6_-_26659685 11.68 ENST00000480036.5
ENST00000415922.7
ENST00000622479.4
ENST00000607204.5
ENST00000456172.5
zinc finger protein 322
chr12_-_89524734 11.59 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr11_-_74398378 11.57 ENST00000298198.5
phosphoglucomutase 2 like 1
chr15_-_45522747 11.40 ENST00000261867.5
solute carrier family 30 member 4
chr12_-_42238203 11.38 ENST00000327791.8
ENST00000534854.7
YY1 associated factor 2
chr12_+_4273751 11.32 ENST00000675880.1
ENST00000261254.8
cyclin D2
chr17_-_16215520 11.20 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
nuclear receptor corepressor 1
chr2_+_17541157 11.10 ENST00000406397.1
visinin like 1
chr9_-_69672341 11.09 ENST00000265381.7
amyloid beta precursor protein binding family A member 1
chr7_-_72336995 11.07 ENST00000329008.9
calneuron 1
chr2_+_66435558 11.06 ENST00000488550.5
Meis homeobox 1
chr14_+_73644875 10.86 ENST00000554113.5
ENST00000553645.7
ENST00000555631.6
ENST00000311089.7
ENST00000555919.7
ENST00000554339.5
ENST00000554871.5
dynein axonemal light chain 1
chr16_-_2858154 10.73 ENST00000571228.1
ENST00000161006.8
serine protease 22
chr1_+_56645299 10.70 ENST00000371244.9
ENST00000610361.1
protein kinase AMP-activated catalytic subunit alpha 2
chr19_+_50025714 10.61 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
zinc finger protein 473
chr8_+_28494190 10.61 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
frizzled class receptor 3
chr11_+_76860859 10.56 ENST00000679754.1
ENST00000534206.5
ENST00000680583.1
ENST00000532485.6
ENST00000526597.5
ENST00000533873.1
alkaline ceramidase 3
chrX_-_54043927 10.45 ENST00000415025.5
ENST00000338946.10
PHD finger protein 8
chr14_+_99684283 10.45 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr16_+_84648502 10.38 ENST00000564996.6
ENST00000258157.9
ENST00000567410.5
kelch like family member 36
chr17_+_79778135 10.37 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr9_+_116153783 10.36 ENST00000328252.4
pappalysin 1
chr17_-_63700100 10.35 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chr1_-_117929557 10.30 ENST00000369442.3
ENST00000369443.10
ganglioside induced differentiation associated protein 2
chr12_+_104064520 10.23 ENST00000229330.9
host cell factor C2
chrX_+_153642473 10.19 ENST00000370167.8
dual specificity phosphatase 9
chr1_-_115089414 10.19 ENST00000433172.3
ENST00000369515.6
ENST00000369516.7
tetraspanin 2
chr1_+_212950572 10.18 ENST00000366968.8
ENST00000490792.1
ENST00000366964.7
vasohibin 2
chr8_-_81112055 10.14 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr3_-_53046031 10.06 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr12_-_49060742 10.02 ENST00000301067.12
ENST00000683543.1
lysine methyltransferase 2D
chr9_-_74887914 10.01 ENST00000360774.6
transient receptor potential cation channel subfamily M member 6
chr10_+_102918276 9.85 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chr2_-_152099023 9.77 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
calcium voltage-gated channel auxiliary subunit beta 4
chr1_+_155859550 9.74 ENST00000368324.5
synaptotagmin 11
chr19_+_33796846 9.70 ENST00000590771.5
ENST00000589786.5
ENST00000284006.10
ENST00000683859.1
ENST00000588881.5
potassium channel tetramerization domain containing 15
chr19_+_46746046 9.68 ENST00000601299.5
ENST00000595570.5
ENST00000598271.5
ENST00000597313.5
ENST00000593875.5
ENST00000391909.7
ENST00000318584.10
ENST00000602250.5
ENST00000595868.5
ENST00000600629.5
ENST00000602181.5
ENST00000593800.5
ENST00000600227.5
ENST00000600005.5
ENST00000594467.5
ENST00000596460.5
fukutin related protein
chr3_-_39051935 9.64 ENST00000668754.1
ENST00000302328.9
sodium voltage-gated channel alpha subunit 11
chr3_-_101320558 9.61 ENST00000193391.8
interphotoreceptor matrix proteoglycan 2
chr4_+_71339014 9.56 ENST00000340595.4
solute carrier family 4 member 4
chr9_+_99906646 9.48 ENST00000259400.11
ENST00000531035.5
ENST00000525640.5
ENST00000534052.1
ENST00000526607.1
syntaxin 17
chr5_+_177133741 9.41 ENST00000439151.7
nuclear receptor binding SET domain protein 1
chr3_-_183555696 9.41 ENST00000341319.8
kelch like family member 6
chr5_-_148654522 9.37 ENST00000377888.8
5-hydroxytryptamine receptor 4
chr4_+_55948871 9.31 ENST00000422247.6
ENST00000257287.5
centrosomal protein 135
chr12_-_89526253 9.27 ENST00000547474.1
POC1B-GALNT4 readthrough
chr17_-_60526167 9.20 ENST00000083182.8
amyloid beta precursor protein binding protein 2
chr13_+_48975879 9.13 ENST00000492622.6
fibronectin type III domain containing 3A
chr1_+_204516375 8.99 ENST00000367183.7
ENST00000391947.6
ENST00000454264.6
ENST00000612738.4
ENST00000614459.4
ENST00000616250.4
ENST00000621032.4
ENST00000367182.8
MDM4 regulator of p53
chr12_-_13981544 8.99 ENST00000609686.4
glutamate ionotropic receptor NMDA type subunit 2B
chr1_-_169893876 8.99 ENST00000367771.11
ENST00000367772.8
SCY1 like pseudokinase 3
chr4_+_55346213 8.96 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr7_-_138981307 8.91 ENST00000440172.5
ENST00000422774.2
KIAA1549
chr19_+_1450113 8.89 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC regulator of WNT signaling pathway 2
chr3_+_185282941 8.87 ENST00000448876.5
ENST00000446828.5
ENST00000447637.1
ENST00000424227.5
ENST00000454237.1
mitogen-activated protein kinase kinase kinase 13
chr11_+_17734732 8.84 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr10_-_49539112 8.83 ENST00000355832.10
ENST00000447839.7
ERCC excision repair 6, chromatin remodeling factor
chr3_+_38453832 8.75 ENST00000352511.5
activin A receptor type 2B
chr1_+_15617415 8.70 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr12_-_95217373 8.61 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr3_+_50674896 8.57 ENST00000266037.10
dedicator of cytokinesis 3
chr10_+_96832252 8.53 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr22_+_21417357 8.44 ENST00000407464.7
HIC ZBTB transcriptional repressor 2
chr10_+_99659430 8.41 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr1_-_147172456 8.40 ENST00000254101.4
protein kinase AMP-activated non-catalytic subunit beta 2
chr3_+_119468952 8.23 ENST00000476573.5
ENST00000295588.9
protein O-glucosyltransferase 1
chr5_-_32312913 8.19 ENST00000280285.9
ENST00000382142.8
ENST00000264934.5
myotubularin related protein 12
chr8_+_69466617 8.14 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr3_-_86991135 8.11 ENST00000398399.7
vestigial like family member 3
chr15_+_74173693 8.09 ENST00000249842.8
immunoglobulin superfamily containing leucine rich repeat
chr8_-_37966582 8.01 ENST00000345060.5
adrenoceptor beta 3
chr6_+_116681176 8.00 ENST00000413340.5
ENST00000356348.6
ENST00000368564.7
karyopherin subunit alpha 5
chr11_-_72434330 7.96 ENST00000542555.2
ENST00000535990.5
ENST00000294053.9
ENST00000538039.6
ENST00000340729.9
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chrX_+_148500610 7.93 ENST00000370460.7
AF4/FMR2 family member 2
chr14_+_102362931 7.85 ENST00000359520.12
tectonin beta-propeller repeat containing 2
chr13_-_113490683 7.77 ENST00000332592.7
ENST00000439909.2
ENST00000478244.6
defective in cullin neddylation 1 domain containing 2
chr14_-_52069039 7.75 ENST00000216286.10
nidogen 2
chr2_+_112482133 7.72 ENST00000233336.7
tubulin tyrosine ligase
chr17_+_28042660 7.72 ENST00000407008.8
nemo like kinase
chrX_-_45200828 7.67 ENST00000398000.7
divergent protein kinase domain 2B
chr1_-_57424014 7.64 ENST00000371230.1
ENST00000371236.7
DAB adaptor protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 51.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
8.0 32.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
7.5 67.8 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
7.4 22.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
7.1 49.8 GO:0051013 microtubule severing(GO:0051013)
7.0 21.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
6.3 19.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
5.9 17.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
5.9 17.6 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
5.9 17.6 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
5.8 28.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
5.7 17.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
5.6 16.7 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
5.6 33.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
5.3 21.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
5.2 30.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
5.0 20.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
4.8 19.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
4.8 14.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
4.7 14.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
4.5 13.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
4.2 12.7 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
4.2 12.5 GO:0051136 regulation of extrathymic T cell differentiation(GO:0033082) regulation of NK T cell differentiation(GO:0051136) sebum secreting cell proliferation(GO:1990654)
4.0 11.9 GO:0009386 translational attenuation(GO:0009386)
3.9 23.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
3.7 40.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
3.6 3.6 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
3.5 10.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
3.2 9.7 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154)
3.2 9.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
3.1 12.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
3.1 3.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
3.0 12.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
2.9 40.6 GO:0043589 skin morphogenesis(GO:0043589)
2.9 17.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
2.7 24.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
2.7 15.9 GO:0048549 positive regulation of pinocytosis(GO:0048549)
2.7 10.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
2.6 21.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
2.5 7.6 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
2.5 7.6 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
2.4 31.4 GO:0015074 DNA integration(GO:0015074)
2.4 12.0 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
2.4 7.2 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
2.3 6.9 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of endothelial cell chemotaxis(GO:2001027)
2.3 16.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
2.3 15.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
2.2 9.0 GO:0016095 polyprenol catabolic process(GO:0016095)
2.2 8.8 GO:0021759 globus pallidus development(GO:0021759)
2.2 39.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
2.2 21.5 GO:0080182 DNA methylation involved in embryo development(GO:0043045) histone H3-K4 trimethylation(GO:0080182) changes to DNA methylation involved in embryo development(GO:1901538)
2.1 4.2 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
2.0 12.2 GO:0016926 protein desumoylation(GO:0016926)
2.0 6.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.0 10.0 GO:0001555 oocyte growth(GO:0001555)
2.0 6.0 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
2.0 5.9 GO:0043504 mitochondrial DNA repair(GO:0043504)
1.9 3.9 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
1.9 3.9 GO:0046666 retinal cell programmed cell death(GO:0046666)
1.9 30.9 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
1.9 9.5 GO:0016240 autophagosome docking(GO:0016240)
1.9 5.7 GO:0048865 stem cell fate commitment(GO:0048865)
1.9 5.6 GO:0007525 somatic muscle development(GO:0007525) convergent extension involved in axis elongation(GO:0060028)
1.8 29.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.7 5.2 GO:1903059 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
1.7 10.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
1.7 5.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
1.7 10.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.7 21.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
1.6 13.2 GO:0070166 enamel mineralization(GO:0070166)
1.6 4.9 GO:0051040 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
1.6 9.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
1.6 8.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
1.6 6.4 GO:1990637 response to prolactin(GO:1990637)
1.6 11.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
1.6 12.8 GO:0007256 activation of JNKK activity(GO:0007256)
1.6 12.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.6 20.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
1.6 17.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.6 4.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.5 13.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.5 4.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.5 11.8 GO:0032455 nerve growth factor processing(GO:0032455)
1.4 18.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.4 4.2 GO:0036166 cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) phenotypic switching(GO:0036166) negative regulation of phospholipid biosynthetic process(GO:0071072) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of phenotypic switching(GO:1900239) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
1.4 8.2 GO:0048318 axial mesoderm development(GO:0048318)
1.3 5.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.3 4.0 GO:0019075 virus maturation(GO:0019075)
1.3 7.9 GO:0035063 nuclear speck organization(GO:0035063)
1.3 21.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.2 18.6 GO:0006600 creatine metabolic process(GO:0006600)
1.2 14.7 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
1.2 15.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
1.1 6.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.1 4.5 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
1.1 35.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
1.1 4.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.1 9.0 GO:0045023 G0 to G1 transition(GO:0045023)
1.1 5.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.0 9.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
1.0 6.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
1.0 5.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
1.0 6.8 GO:0018095 protein polyglutamylation(GO:0018095)
1.0 10.6 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
1.0 3.8 GO:0035627 ceramide transport(GO:0035627)
0.9 17.9 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.9 9.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.9 5.6 GO:0050893 sensory processing(GO:0050893)
0.9 2.7 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.9 3.6 GO:0021571 rhombomere 5 development(GO:0021571)
0.9 2.7 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.9 5.3 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.9 19.1 GO:0006853 carnitine shuttle(GO:0006853)
0.9 6.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.9 2.6 GO:0002384 hepatic immune response(GO:0002384)
0.9 11.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.8 7.5 GO:0060346 bone trabecula formation(GO:0060346)
0.8 8.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.8 2.4 GO:1901860 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) response to norepinephrine(GO:0071873) positive regulation of mitochondrial DNA metabolic process(GO:1901860) regulation of progesterone biosynthetic process(GO:2000182)
0.8 6.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.8 4.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.8 9.4 GO:0002467 germinal center formation(GO:0002467)
0.8 12.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.8 11.7 GO:0043586 tongue development(GO:0043586)
0.8 10.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.8 6.9 GO:0032119 sequestering of zinc ion(GO:0032119)
0.8 3.1 GO:0019086 late viral transcription(GO:0019086)
0.8 3.8 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.8 2.3 GO:0043016 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.7 20.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.7 8.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.7 13.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.7 4.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.7 7.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 17.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.7 3.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.7 4.9 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.7 2.8 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.7 6.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 2.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.7 4.8 GO:0015811 L-cystine transport(GO:0015811)
0.7 13.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.7 3.4 GO:0033504 floor plate development(GO:0033504)
0.6 14.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.6 21.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.6 20.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.6 22.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.6 1.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.6 12.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.6 13.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.6 24.4 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.6 0.6 GO:1905069 negative regulation of mononuclear cell migration(GO:0071676) allantois development(GO:1905069)
0.6 9.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.6 1.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.5 4.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.5 10.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.5 3.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.5 4.0 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.5 9.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.5 6.9 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.5 2.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 4.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.4 5.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 3.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.4 8.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.4 6.9 GO:0021670 lateral ventricle development(GO:0021670)
0.4 5.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4 9.4 GO:0032098 regulation of appetite(GO:0032098)
0.4 3.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.4 16.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.4 2.9 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.4 2.1 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) regulation of vascular smooth muscle contraction(GO:0003056)
0.4 10.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.4 6.9 GO:0014029 neural crest formation(GO:0014029)
0.4 4.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 11.3 GO:0007616 long-term memory(GO:0007616)
0.4 1.6 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.4 4.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 19.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.4 12.6 GO:0071711 basement membrane organization(GO:0071711)
0.4 9.1 GO:0060009 Sertoli cell development(GO:0060009)
0.4 20.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.4 4.8 GO:0045008 depyrimidination(GO:0045008)
0.4 5.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 6.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.4 19.3 GO:0019228 neuronal action potential(GO:0019228)
0.3 14.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.3 7.7 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.3 9.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 15.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 12.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 11.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 1.2 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.3 3.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 11.1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.3 4.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 14.9 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.3 2.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 3.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.3 6.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.3 7.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 5.8 GO:0070932 histone H3 deacetylation(GO:0070932)
0.3 1.5 GO:0015853 adenine transport(GO:0015853)
0.2 19.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 2.4 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.2 8.2 GO:1901998 toxin transport(GO:1901998)
0.2 12.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 5.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.2 1.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 4.7 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.2 9.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 10.5 GO:0030500 regulation of bone mineralization(GO:0030500)
0.2 5.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 2.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 13.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 4.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 3.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.2 7.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 13.3 GO:0030574 collagen catabolic process(GO:0030574)
0.2 2.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 4.2 GO:0097503 sialylation(GO:0097503)
0.2 6.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.2 7.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 9.6 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 5.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.2 8.9 GO:0030279 negative regulation of ossification(GO:0030279)
0.2 13.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 16.2 GO:0032526 response to retinoic acid(GO:0032526)
0.2 3.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 7.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 3.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 0.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 14.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 2.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.5 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.1 1.5 GO:0034378 chylomicron assembly(GO:0034378)
0.1 8.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 5.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 16.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 5.6 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 1.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.8 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 1.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 23.3 GO:0007601 visual perception(GO:0007601)
0.1 6.6 GO:0042472 inner ear morphogenesis(GO:0042472)
0.1 6.1 GO:0046847 filopodium assembly(GO:0046847)
0.1 5.2 GO:0048477 oogenesis(GO:0048477)
0.1 6.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 4.2 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 2.5 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 3.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 2.3 GO:0010107 potassium ion import(GO:0010107)
0.1 7.2 GO:0031623 receptor internalization(GO:0031623)
0.1 0.4 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.1 2.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.0 GO:0007030 Golgi organization(GO:0007030)
0.1 1.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 5.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 6.2 GO:0007626 locomotory behavior(GO:0007626)
0.0 4.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 3.4 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 4.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 8.6 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 3.7 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 10.1 GO:0002250 adaptive immune response(GO:0002250)
0.0 3.1 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 2.4 GO:0006310 DNA recombination(GO:0006310)
0.0 0.6 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 33.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
4.9 14.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
4.7 19.0 GO:0070695 FHF complex(GO:0070695)
4.3 13.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
4.2 12.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
4.0 52.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
4.0 67.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
3.6 21.5 GO:0001940 male pronucleus(GO:0001940)
3.4 17.2 GO:0044308 axonal spine(GO:0044308)
3.2 19.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.3 25.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
2.3 15.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
2.2 6.7 GO:0070195 growth hormone receptor complex(GO:0070195)
2.0 5.9 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.9 30.9 GO:0031083 BLOC-1 complex(GO:0031083)
1.9 11.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.8 12.9 GO:0005683 U7 snRNP(GO:0005683)
1.8 15.9 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
1.7 5.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.6 9.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.6 12.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.6 10.9 GO:0036157 outer dynein arm(GO:0036157)
1.4 24.8 GO:0005662 DNA replication factor A complex(GO:0005662)
1.3 20.1 GO:0097418 neurofibrillary tangle(GO:0097418)
1.3 21.1 GO:0016600 flotillin complex(GO:0016600)
1.3 5.2 GO:0048179 activin receptor complex(GO:0048179)
1.2 5.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.2 7.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.2 9.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.2 17.6 GO:0030478 actin cap(GO:0030478)
1.1 4.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.1 21.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.9 10.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.9 2.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.9 4.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.8 3.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.8 3.9 GO:1990425 ryanodine receptor complex(GO:1990425)
0.7 21.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.7 17.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.7 8.9 GO:0016342 catenin complex(GO:0016342)
0.7 4.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.7 15.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 10.4 GO:0035102 PRC1 complex(GO:0035102)
0.6 9.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.6 3.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.6 9.9 GO:0097440 apical dendrite(GO:0097440)
0.6 6.9 GO:0005577 fibrinogen complex(GO:0005577)
0.5 2.1 GO:0097165 nuclear stress granule(GO:0097165)
0.5 2.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 3.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.5 5.8 GO:0016013 syntrophin complex(GO:0016013)
0.4 3.6 GO:0061700 GATOR2 complex(GO:0061700)
0.4 1.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 4.0 GO:0000813 ESCRT I complex(GO:0000813)
0.4 11.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.4 3.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 12.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 3.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.4 9.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 7.3 GO:0016580 Sin3 complex(GO:0016580)
0.4 17.7 GO:0048786 presynaptic active zone(GO:0048786)
0.3 3.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 49.2 GO:0016605 PML body(GO:0016605)
0.3 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 10.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 8.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 6.3 GO:0044295 axonal growth cone(GO:0044295)
0.2 7.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 4.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 4.3 GO:0031045 dense core granule(GO:0031045)
0.2 2.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 14.7 GO:0055037 recycling endosome(GO:0055037)
0.2 28.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 12.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 0.4 GO:0043196 varicosity(GO:0043196)
0.2 3.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 5.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.8 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2 17.5 GO:0005814 centriole(GO:0005814)
0.2 27.0 GO:0001650 fibrillar center(GO:0001650)
0.2 13.1 GO:0060170 ciliary membrane(GO:0060170)
0.2 11.7 GO:0043209 myelin sheath(GO:0043209)
0.2 18.2 GO:0036064 ciliary basal body(GO:0036064)
0.2 11.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 75.7 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 19.9 GO:0005796 Golgi lumen(GO:0005796)
0.2 28.8 GO:0030426 growth cone(GO:0030426)
0.2 1.1 GO:0051286 cell tip(GO:0051286)
0.2 8.6 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 15.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 39.7 GO:0005769 early endosome(GO:0005769)
0.1 28.8 GO:0030027 lamellipodium(GO:0030027)
0.1 5.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 45.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 8.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 5.4 GO:0031526 brush border membrane(GO:0031526)
0.1 9.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 5.7 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 7.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 54.5 GO:0005874 microtubule(GO:0005874)
0.1 3.6 GO:0030120 vesicle coat(GO:0030120)
0.1 11.9 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 3.1 GO:0005581 collagen trimer(GO:0005581)
0.1 2.1 GO:0035861 site of double-strand break(GO:0035861)
0.1 7.6 GO:0005903 brush border(GO:0005903)
0.1 15.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 6.1 GO:0015030 Cajal body(GO:0015030)
0.1 13.1 GO:0043296 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296)
0.1 2.6 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.8 GO:0031010 ISWI-type complex(GO:0031010)
0.1 19.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 8.3 GO:0008021 synaptic vesicle(GO:0008021)
0.1 8.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 11.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 6.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 33.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 25.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 15.4 GO:0043235 receptor complex(GO:0043235)
0.1 11.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 7.3 GO:0005911 cell-cell junction(GO:0005911)
0.1 6.4 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 2.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.6 GO:0031672 A band(GO:0031672)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 3.6 GO:0001726 ruffle(GO:0001726)
0.0 2.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 22.0 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.8 51.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
9.9 39.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
7.4 22.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
7.1 49.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
6.3 19.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
6.3 18.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
5.9 35.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
5.8 34.9 GO:0061665 SUMO ligase activity(GO:0061665)
5.4 21.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
5.3 68.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
4.8 14.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
3.9 19.6 GO:0004803 transposase activity(GO:0004803)
3.6 10.7 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
3.5 10.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
3.3 13.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
3.1 37.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
3.0 12.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
3.0 9.0 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
2.9 11.8 GO:0005163 nerve growth factor receptor binding(GO:0005163)
2.7 32.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
2.7 16.0 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
2.3 21.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
2.3 6.9 GO:0070052 collagen V binding(GO:0070052)
2.2 24.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
2.0 12.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.9 11.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.9 9.4 GO:0001594 trace-amine receptor activity(GO:0001594)
1.8 30.5 GO:0009881 photoreceptor activity(GO:0009881)
1.8 5.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
1.8 10.6 GO:0017040 ceramidase activity(GO:0017040)
1.8 7.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.6 4.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.6 14.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
1.6 9.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
1.4 15.8 GO:0017002 activin-activated receptor activity(GO:0017002)
1.4 6.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.3 9.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.3 3.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.2 5.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.2 7.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.2 4.8 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
1.2 3.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.2 5.9 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
1.1 27.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.1 3.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.1 15.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.1 59.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.0 5.0 GO:0004370 glycerol kinase activity(GO:0004370)
1.0 3.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.0 4.9 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
1.0 14.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
1.0 21.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.0 3.8 GO:0097001 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.9 3.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.9 11.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.9 4.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.9 2.7 GO:0004336 galactosylceramidase activity(GO:0004336)
0.9 9.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.9 2.6 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.8 7.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.8 29.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.8 27.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.8 3.9 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.8 10.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.8 8.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.8 17.4 GO:0051787 misfolded protein binding(GO:0051787)
0.8 4.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.7 17.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.7 6.0 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.7 5.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.7 23.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.7 15.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.7 12.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 4.8 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.7 8.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.7 19.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.7 9.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.7 2.0 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.6 3.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 4.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 20.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.6 7.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 6.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.6 4.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.6 5.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.6 5.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.6 19.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6 10.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.5 2.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 4.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 2.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 1.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.5 7.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.5 8.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 12.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 4.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 61.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 9.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.5 22.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.5 7.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 4.9 GO:0039706 co-receptor binding(GO:0039706)
0.4 6.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 44.4 GO:0019905 syntaxin binding(GO:0019905)
0.4 9.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.4 5.6 GO:0015643 toxic substance binding(GO:0015643)
0.4 14.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.4 9.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 12.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.4 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.4 12.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.4 2.4 GO:0008142 oxysterol binding(GO:0008142)
0.4 1.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 3.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 7.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.4 3.4 GO:0045545 syndecan binding(GO:0045545)
0.4 1.5 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.4 11.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 21.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.3 3.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 3.1 GO:0003696 satellite DNA binding(GO:0003696)
0.3 5.4 GO:0005112 Notch binding(GO:0005112)
0.3 4.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 4.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 12.9 GO:0017069 snRNA binding(GO:0017069)
0.3 23.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 2.9 GO:0016015 morphogen activity(GO:0016015)
0.3 36.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 4.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 8.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 3.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 7.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 33.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 25.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.3 19.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3 8.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 6.9 GO:0071837 HMG box domain binding(GO:0071837)
0.3 12.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 5.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 3.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.3 6.9 GO:0005523 tropomyosin binding(GO:0005523)
0.3 3.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 5.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 109.7 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 7.7 GO:0042169 SH2 domain binding(GO:0042169)
0.2 17.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 13.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 5.6 GO:0070412 R-SMAD binding(GO:0070412)
0.2 16.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 21.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 13.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 25.4 GO:0019208 phosphatase regulator activity(GO:0019208)
0.2 2.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 3.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 2.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 6.7 GO:0017046 peptide hormone binding(GO:0017046)
0.2 4.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 15.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.2 6.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 1.1 GO:0030911 TPR domain binding(GO:0030911)
0.2 7.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 34.5 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.2 5.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 6.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 20.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 3.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 8.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 10.0 GO:0005262 calcium channel activity(GO:0005262)
0.1 13.5 GO:0043130 ubiquitin binding(GO:0043130)
0.1 20.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 5.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 6.8 GO:0004527 exonuclease activity(GO:0004527)
0.1 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 4.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 4.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 4.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 14.1 GO:0005126 cytokine receptor binding(GO:0005126)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 1.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 5.3 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.1 3.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 11.0 GO:0008017 microtubule binding(GO:0008017)
0.1 2.4 GO:0005518 collagen binding(GO:0005518)
0.1 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 11.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 11.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 11.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 3.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 7.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
1.7 80.8 NABA COLLAGENS Genes encoding collagen proteins
1.2 13.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.0 6.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
1.0 33.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.9 17.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.9 10.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.9 62.8 PID IFNG PATHWAY IFN-gamma pathway
0.7 20.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.7 7.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.6 20.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.6 5.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 14.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.5 26.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.5 8.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 9.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4 9.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 16.6 PID REELIN PATHWAY Reelin signaling pathway
0.4 18.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 15.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 18.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.4 26.6 PID LKB1 PATHWAY LKB1 signaling events
0.3 9.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 2.6 ST STAT3 PATHWAY STAT3 Pathway
0.3 16.6 PID ARF6 PATHWAY Arf6 signaling events
0.3 6.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 8.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 13.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 31.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 7.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 10.6 PID ALK1 PATHWAY ALK1 signaling events
0.3 9.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 11.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 8.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 6.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 3.8 PID IGF1 PATHWAY IGF1 pathway
0.2 19.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 20.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 3.0 ST GA12 PATHWAY G alpha 12 Pathway
0.2 6.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 14.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 4.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 7.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 11.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 7.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 5.3 PID BMP PATHWAY BMP receptor signaling
0.1 4.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 14.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 6.3 PID P73PATHWAY p73 transcription factor network
0.1 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 6.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 11.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.9 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 40.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.3 39.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.6 23.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.4 21.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
1.4 23.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.4 27.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
1.2 22.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.1 5.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.0 17.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.9 11.8 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.9 9.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.9 12.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.8 20.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.8 22.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.8 12.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.8 21.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.7 15.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.7 7.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.7 20.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.7 26.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6 32.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 9.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.6 8.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.6 40.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.6 9.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.6 13.0 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.6 32.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 6.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.5 7.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 5.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.5 6.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.5 10.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 3.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 14.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 10.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 12.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 15.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 6.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 5.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.4 5.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 3.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 8.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.3 13.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3 10.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 20.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 14.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 4.8 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.3 20.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.3 26.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 2.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 5.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3 15.8 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.3 6.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 10.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 2.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 5.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 12.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 6.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 4.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 6.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 4.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 2.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 6.9 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 3.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 14.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 7.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 3.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 13.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 9.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 3.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 6.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 5.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 6.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 7.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 11.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 10.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.5 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse