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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GATA1_GATA4

Z-value: 4.39

Motif logo

Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
ENSG00000102145.15 GATA1
ENSG00000136574.19 GATA4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA1hg38_v1_chrX_+_48786578_487865970.601.1e-22Click!
GATA4hg38_v1_chr8_+_11676952_116769660.471.5e-13Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_43220989 66.14 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
erythrocyte membrane protein band 4.2
chr12_-_54295748 41.55 ENST00000540264.2
ENST00000312156.8
nuclear factor, erythroid 2
chr1_+_25272439 41.34 ENST00000648012.1
Rh blood group D antigen
chr1_+_25272492 40.40 ENST00000454452.6
Rh blood group D antigen
chr19_-_13102848 30.71 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr10_+_116545907 30.34 ENST00000369221.2
pancreatic lipase
chr6_-_35797313 28.17 ENST00000259938.7
ENST00000616014.3
colipase
chr19_-_12887188 27.49 ENST00000264834.6
Kruppel like factor 1
chr7_+_130380339 26.39 ENST00000481342.5
ENST00000604896.5
ENST00000011292.8
carboxypeptidase A1
chr11_-_5249836 26.39 ENST00000632727.1
ENST00000330597.5
hemoglobin subunit gamma 1
chr16_+_152638 25.66 ENST00000252951.3
hemoglobin subunit zeta
chr1_+_25272502 25.19 ENST00000328664.9
Rh blood group D antigen
chr1_+_25272527 24.45 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr6_+_41042557 23.84 ENST00000373158.6
ENST00000470917.1
translocator protein 2
chr1_+_25272479 23.52 ENST00000622561.4
Rh blood group D antigen
chr6_+_41042462 23.09 ENST00000373161.6
translocator protein 2
chr14_+_24114627 22.73 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr10_-_97771954 22.35 ENST00000266066.4
secreted frizzled related protein 5
chr6_-_52803807 21.16 ENST00000334575.6
glutathione S-transferase alpha 1
chr16_-_75207152 20.03 ENST00000303037.13
chymotrypsinogen B2
chr11_-_116837586 19.87 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
apolipoprotein A1
chr7_+_142760398 19.86 ENST00000632998.1
serine protease 2
chr7_-_100641507 19.42 ENST00000431692.5
ENST00000223051.8
transferrin receptor 2
chr1_+_22001654 19.37 ENST00000290122.8
chymotrypsin like elastase 3A
chr1_+_159204860 19.09 ENST00000368122.4
ENST00000368121.6
atypical chemokine receptor 1 (Duffy blood group)
chr7_+_142749465 18.98 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
serine protease 1
chr12_-_114403898 18.46 ENST00000526441.1
T-box transcription factor 5
chr11_+_119087979 18.30 ENST00000535253.5
ENST00000392841.1
ENST00000648374.1
hydroxymethylbilane synthase
chr19_-_55157725 17.90 ENST00000344887.10
ENST00000665070.1
troponin I3, cardiac type
chr1_+_21977014 17.88 ENST00000337107.11
chymotrypsin like elastase 3B
chrX_-_55030970 17.30 ENST00000493869.2
ENST00000396198.7
ENST00000650242.1
ENST00000335854.8
ENST00000477869.6
ENST00000455688.2
ENST00000644983.1
5'-aminolevulinate synthase 2
chr12_-_120327762 16.75 ENST00000308366.9
ENST00000423423.3
phospholipase A2 group IB
chr16_+_31527876 16.44 ENST00000302312.9
ENST00000564707.1
alpha hemoglobin stabilizing protein
chr14_+_24115299 16.38 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr7_-_142962206 16.00 ENST00000460479.2
ENST00000476829.5
ENST00000355265.7
Kell metallo-endopeptidase (Kell blood group)
chr1_-_158686700 15.36 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr19_-_11384299 15.23 ENST00000592375.6
ENST00000222139.11
erythropoietin receptor
chr7_-_99735093 14.97 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr18_+_22169580 14.67 ENST00000269216.10
GATA binding protein 6
chrX_-_19965142 14.66 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr19_+_10286944 14.57 ENST00000380770.5
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr4_-_144019287 14.51 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chrX_+_47078434 14.49 ENST00000397180.6
regucalcin
chrX_+_47078380 14.43 ENST00000352078.8
regucalcin
chr1_-_25420792 14.13 ENST00000346452.8
ENST00000340849.8
ENST00000349438.8
ENST00000413854.5
ENST00000294413.13
Rh blood group CcEe antigens
chr6_-_30160880 14.10 ENST00000376704.3
tripartite motif containing 10
chr7_+_80646305 14.07 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr19_+_10286971 13.95 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr16_+_58249910 13.42 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr7_+_80646436 13.23 ENST00000419819.2
CD36 molecule
chr4_-_71784046 13.22 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr14_-_24114913 13.08 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr1_+_42825548 12.80 ENST00000372514.7
erythroblast membrane associated protein (Scianna blood group)
chr12_-_91179355 12.67 ENST00000550563.5
ENST00000546370.5
decorin
chr4_+_73404255 12.16 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
albumin
chr17_-_49764123 12.11 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr4_+_73409340 12.10 ENST00000511370.1
albumin
chr11_-_57390636 11.86 ENST00000525955.1
ENST00000533605.5
ENST00000311862.10
proteoglycan 2, pro eosinophil major basic protein
chr9_+_33795551 11.64 ENST00000379405.4
serine protease 3
chr2_+_3595049 11.48 ENST00000236693.11
ENST00000349077.9
collectin subfamily member 11
chr4_-_144140683 11.46 ENST00000324022.14
glycophorin A (MNS blood group)
chr6_-_46921926 11.07 ENST00000283296.12
adhesion G protein-coupled receptor F5
chr10_+_116621306 11.01 ENST00000611850.4
ENST00000591655.3
pancreatic lipase related protein 2 (gene/pseudogene)
chr1_-_206023889 10.82 ENST00000358184.7
ENST00000360218.3
ENST00000678712.1
ENST00000678498.1
cathepsin E
chr4_-_144140635 10.80 ENST00000512064.5
ENST00000512789.5
ENST00000504786.5
ENST00000503627.2
ENST00000642713.1
ENST00000643148.1
ENST00000642738.1
ENST00000642295.1
ENST00000646447.1
ENST00000535709.6
glycophorin A (MNS blood group)
chr19_-_51065067 10.78 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr10_+_116591010 10.52 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
pancreatic lipase related protein 1
chrX_-_66033664 10.34 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr7_-_99679987 10.31 ENST00000222982.8
ENST00000439761.3
ENST00000339843.6
cytochrome P450 family 3 subfamily A member 5
chr1_-_155301423 10.18 ENST00000342741.6
pyruvate kinase L/R
chr1_-_54406385 10.17 ENST00000610401.5
single stranded DNA binding protein 3
chr10_+_116590956 10.09 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr12_-_9999176 10.04 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr8_-_41797589 9.82 ENST00000347528.8
ENST00000289734.13
ankyrin 1
chr7_-_99784248 9.74 ENST00000652018.1
cytochrome P450 family 3 subfamily A member 4
chr12_+_6310669 9.68 ENST00000684764.1
pleckstrin homology and RhoGEF domain containing G6
chr6_-_30161200 9.59 ENST00000449742.7
tripartite motif containing 10
chr6_-_33200614 9.53 ENST00000374685.8
ENST00000374680.4
retinoid X receptor beta
chr1_+_15456727 9.42 ENST00000359621.5
chymotrypsin like elastase 2A
chr2_+_234050732 9.30 ENST00000425558.1
secreted phosphoprotein 2
chr16_+_283157 9.25 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr2_+_200440649 9.22 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr17_-_66229380 9.17 ENST00000205948.11
apolipoprotein H
chr6_-_52763473 9.10 ENST00000493422.3
glutathione S-transferase alpha 2
chrX_+_38352573 9.08 ENST00000039007.5
ornithine transcarbamylase
chr14_+_94581407 8.98 ENST00000553511.1
ENST00000329597.12
ENST00000554633.5
ENST00000555681.1
ENST00000554276.1
serpin family A member 5
chr4_-_143905529 8.88 ENST00000358615.9
ENST00000437468.2
glycophorin E (MNS blood group)
chr11_-_5269933 8.87 ENST00000396895.3
hemoglobin subunit epsilon 1
chr7_-_150955796 8.80 ENST00000330883.9
potassium voltage-gated channel subfamily H member 2
chr8_-_71361860 8.78 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr1_-_26913964 8.73 ENST00000254227.4
nuclear receptor subfamily 0 group B member 2
chrX_-_154805386 8.61 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr12_-_21775581 8.43 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr1_-_24143112 8.37 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr4_-_144140712 8.31 ENST00000641688.3
glycophorin A (MNS blood group)
chr4_-_144140725 8.29 ENST00000360771.8
glycophorin A (MNS blood group)
chr19_+_8418386 8.22 ENST00000602117.1
membrane associated ring-CH-type finger 2
chr7_+_142770960 8.19 ENST00000632805.1
ENST00000633969.1
ENST00000539842.6
serine protease 2
chr5_-_135954962 8.16 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chrX_-_154805516 8.14 ENST00000413259.7
membrane palmitoylated protein 1
chr8_-_142879820 8.02 ENST00000377675.3
ENST00000517471.5
ENST00000292427.10
cytochrome P450 family 11 subfamily B member 1
chr19_-_38812936 7.94 ENST00000307751.9
ENST00000594209.1
galectin 4
chr1_+_15476099 7.77 ENST00000375910.8
chymotrypsin like elastase 2B
chr19_+_15640880 7.74 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
cytochrome P450 family 4 subfamily F member 3
chr6_+_29587455 7.73 ENST00000383640.4
olfactory receptor family 2 subfamily H member 2
chrX_+_35798342 7.68 ENST00000399988.5
ENST00000399992.5
ENST00000399987.5
ENST00000399989.5
MAGE family member B16
chr8_-_71362054 7.60 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr4_-_185775890 7.55 ENST00000437304.6
sorbin and SH3 domain containing 2
chr2_+_79120474 7.55 ENST00000233735.2
regenerating family member 1 alpha
chr9_+_33240159 7.51 ENST00000379721.4
serine peptidase inhibitor Kazal type 4
chr2_-_88128049 7.42 ENST00000393750.3
ENST00000295834.8
fatty acid binding protein 1
chr2_+_234050679 7.39 ENST00000373368.5
ENST00000168148.8
secreted phosphoprotein 2
chr12_-_9115907 7.37 ENST00000318602.12
alpha-2-macroglobulin
chr3_-_98593589 7.35 ENST00000647941.2
coproporphyrinogen oxidase
chr17_-_31314066 7.30 ENST00000577894.1
ecotropic viral integration site 2B
chr3_-_167474026 7.29 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr3_-_119660580 7.22 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chr1_-_153041111 7.09 ENST00000360379.4
small proline rich protein 2D
chr17_+_4771878 7.06 ENST00000270560.4
transmembrane 4 L six family member 5
chr16_+_142725 6.96 ENST00000652335.1
hemoglobin subunit zeta
chr8_-_20183090 6.89 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr15_-_58014097 6.86 ENST00000559517.5
aldehyde dehydrogenase 1 family member A2
chr16_+_71526419 6.83 ENST00000539698.4
carbohydrate sulfotransferase 4
chrX_+_35798791 6.83 ENST00000399985.1
MAGE family member B16
chr2_+_137964446 6.80 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr7_-_99784175 6.69 ENST00000651514.1
ENST00000336411.7
ENST00000415003.1
ENST00000354593.6
cytochrome P450 family 3 subfamily A member 4
chr12_+_8950036 6.66 ENST00000539240.5
killer cell lectin like receptor G1
chr19_+_35248994 6.65 ENST00000427250.5
ENST00000605618.6
lipolysis stimulated lipoprotein receptor
chr12_-_91179472 6.65 ENST00000550099.5
ENST00000546391.5
decorin
chr4_-_73982019 6.64 ENST00000296029.4
platelet factor 4
chr1_+_161166390 6.51 ENST00000352210.9
ENST00000367999.9
ENST00000497522.5
ENST00000652182.1
ENST00000544598.5
ENST00000535223.5
protoporphyrinogen oxidase
chr15_-_34318761 6.50 ENST00000290209.9
solute carrier family 12 member 6
chr2_+_219514477 6.44 ENST00000347842.8
ENST00000358078.5
acid sensing ion channel subunit family member 4
chr17_+_39667964 6.41 ENST00000394246.1
phenylethanolamine N-methyltransferase
chr19_+_54724479 6.40 ENST00000291860.1
ENST00000400864.3
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
novel transcript
chr2_-_151973991 6.40 ENST00000534999.6
ENST00000637217.1
ENST00000360283.11
calcium voltage-gated channel auxiliary subunit beta 4
chr5_+_67004618 6.40 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr4_+_153466324 6.36 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr8_-_20183127 6.24 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr12_-_14843517 6.22 ENST00000228936.6
ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
chr1_-_119768892 6.20 ENST00000369406.8
ENST00000544913.2
3-hydroxy-3-methylglutaryl-CoA synthase 2
chr10_-_102837406 6.18 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chr6_+_108559742 6.18 ENST00000343882.10
forkhead box O3
chr19_+_35248879 6.17 ENST00000347609.8
lipolysis stimulated lipoprotein receptor
chr11_-_1036706 6.16 ENST00000421673.7
mucin 6, oligomeric mucus/gel-forming
chr1_-_201399302 6.11 ENST00000633953.1
ENST00000391967.7
ladinin 1
chr1_+_205256189 6.11 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr3_-_58210961 6.06 ENST00000486455.5
ENST00000394549.7
deoxyribonuclease 1 like 3
chr1_-_201399525 6.01 ENST00000367313.4
ladinin 1
chr17_+_4932248 5.98 ENST00000329125.6
glycoprotein Ib platelet subunit alpha
chr1_+_200027702 5.83 ENST00000367362.8
nuclear receptor subfamily 5 group A member 2
chr16_-_55833186 5.79 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr1_-_175192911 5.76 ENST00000444639.5
KIAA0040
chr5_+_141100466 5.74 ENST00000231130.3
protocadherin beta 3
chr2_+_102418642 5.64 ENST00000264260.6
interleukin 18 receptor accessory protein
chr16_+_67806765 5.60 ENST00000415766.7
ENST00000561639.6
translin associated factor X interacting protein 1
chr12_-_6124662 5.57 ENST00000261405.10
von Willebrand factor
chr11_+_10456186 5.54 ENST00000528723.5
adenosine monophosphate deaminase 3
chr1_-_155300979 5.53 ENST00000392414.7
pyruvate kinase L/R
chr8_+_120125093 5.50 ENST00000297848.8
ENST00000309791.8
collagen type XIV alpha 1 chain
chr18_+_45724172 5.48 ENST00000321925.9
ENST00000415427.7
ENST00000589322.7
ENST00000586951.6
ENST00000535474.5
ENST00000402943.6
solute carrier family 14 member 1 (Kidd blood group)
chr8_-_85378105 5.48 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chr1_+_15438435 5.47 ENST00000375943.6
ENST00000375949.5
chymotrypsin C
chr15_-_34337462 5.46 ENST00000676379.1
solute carrier family 12 member 6
chr2_+_102311502 5.46 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr3_-_58211212 5.22 ENST00000461914.7
deoxyribonuclease 1 like 3
chr1_+_119414931 5.15 ENST00000543831.5
ENST00000433745.5
ENST00000369416.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr21_+_42403856 5.05 ENST00000291535.11
ubiquitin associated and SH3 domain containing A
chr14_+_21978440 5.03 ENST00000390443.3
T cell receptor alpha variable 8-6
chr9_-_94593810 4.93 ENST00000375337.4
fructose-bisphosphatase 2
chr17_+_60149966 4.88 ENST00000300900.9
carbonic anhydrase 4
chr2_-_68871382 4.83 ENST00000295379.2
bone morphogenetic protein 10
chr18_+_45724127 4.78 ENST00000619403.4
ENST00000587601.5
solute carrier family 14 member 1 (Kidd blood group)
chr4_-_185812209 4.70 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr12_+_69239560 4.64 ENST00000435070.7
cleavage and polyadenylation specific factor 6
chr22_+_21420636 4.64 ENST00000407598.2
HIC ZBTB transcriptional repressor 2
chr6_-_87095059 4.62 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr14_-_22815856 4.59 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr4_-_99219230 4.56 ENST00000394897.5
ENST00000508558.1
ENST00000394899.6
alcohol dehydrogenase 6 (class V)
chr3_+_50205254 4.55 ENST00000614032.5
ENST00000445096.5
solute carrier family 38 member 3
chrX_+_129779930 4.55 ENST00000356892.4
SAM and SH3 domain containing 3
chr19_-_50823778 4.52 ENST00000301420.3
kallikrein 1
chr8_+_142449430 4.51 ENST00000643448.1
ENST00000517894.5
adhesion G protein-coupled receptor B1
chr2_+_102311546 4.51 ENST00000233954.6
ENST00000447231.5
interleukin 1 receptor like 1
chr7_+_100949525 4.51 ENST00000379458.9
ENST00000483366.5
mucin 3A, cell surface associated
chr1_-_44843240 4.47 ENST00000372192.4
patched 2
chr9_-_13279407 4.47 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr17_+_74432079 4.44 ENST00000392627.7
ENST00000392628.7
ENST00000582473.2
G protein-coupled receptor class C group 5 member C
chr21_-_7825797 4.42 ENST00000617668.2
potassium voltage-gated channel subfamily E regulatory subunit 1B
chr4_-_102345061 4.42 ENST00000394833.6
solute carrier family 39 member 8
chr21_-_42350987 4.41 ENST00000291526.5
trefoil factor 2
chr7_+_150852507 4.39 ENST00000416793.6
ENST00000360937.9
ENST00000483043.1
amine oxidase copper containing 1
chr16_-_67944113 4.39 ENST00000264005.10
lecithin-cholesterol acyltransferase
chr6_+_152697934 4.38 ENST00000532295.1
MYC target 1
chr4_-_121072519 4.38 ENST00000379692.9
neuron derived neurotrophic factor
chr17_+_4932285 4.37 ENST00000611961.1
glycoprotein Ib platelet subunit alpha
chr19_-_50983815 4.37 ENST00000391807.5
ENST00000593904.1
ENST00000595820.6
kallikrein related peptidase 7
chr12_+_12070932 4.36 ENST00000308721.9
BCL2 like 14
chr1_-_161238085 4.27 ENST00000512372.5
ENST00000437437.6
ENST00000412844.6
ENST00000428574.6
ENST00000442691.6
ENST00000505005.5
ENST00000508740.5
ENST00000367981.7
ENST00000502985.5
ENST00000504010.5
ENST00000508387.5
ENST00000511676.5
ENST00000511748.5
ENST00000511944.5
ENST00000515621.5
ENST00000367984.8
ENST00000367985.7
nuclear receptor subfamily 1 group I member 3
chr11_+_128694052 4.24 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 24.3 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
7.9 102.7 GO:0043249 erythrocyte maturation(GO:0043249)
7.6 15.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
7.2 28.9 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
7.2 28.7 GO:0009822 alkaloid catabolic process(GO:0009822)
6.2 18.5 GO:0003218 cardiac left ventricle formation(GO:0003218)
6.1 18.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
5.6 22.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
5.2 175.1 GO:0015695 organic cation transport(GO:0015695)
4.9 14.7 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
4.6 127.7 GO:0044241 lipid digestion(GO:0044241)
3.7 15.0 GO:0002933 lipid hydroxylation(GO:0002933)
3.7 7.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
3.5 17.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
3.2 19.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
3.2 6.4 GO:0042418 epinephrine biosynthetic process(GO:0042418)
3.1 12.5 GO:0002215 defense response to nematode(GO:0002215)
3.0 9.1 GO:0097272 ammonia homeostasis(GO:0097272)
2.9 8.8 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
2.6 7.9 GO:1990451 cellular stress response to acidic pH(GO:1990451)
2.6 10.3 GO:0071918 urea transmembrane transport(GO:0071918)
2.5 7.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.3 16.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.3 16.0 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
2.3 18.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
2.2 26.6 GO:0001955 blood vessel maturation(GO:0001955)
2.2 13.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
2.2 15.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
2.2 34.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
2.1 12.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.1 6.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
2.1 35.3 GO:0015671 oxygen transport(GO:0015671)
2.1 6.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
2.0 4.1 GO:0018963 phthalate metabolic process(GO:0018963)
2.0 56.1 GO:0009235 cobalamin metabolic process(GO:0009235)
2.0 9.9 GO:0061113 pancreas morphogenesis(GO:0061113)
1.9 13.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.9 1.9 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
1.8 5.5 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.8 9.0 GO:0061107 seminal vesicle development(GO:0061107)
1.8 7.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.7 3.3 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
1.6 9.6 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
1.6 14.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.5 9.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.5 4.6 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.5 19.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.5 10.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
1.4 10.1 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
1.4 10.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
1.3 15.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.3 7.7 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
1.2 4.9 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.2 3.7 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
1.2 7.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.2 3.6 GO:0071461 cellular response to redox state(GO:0071461)
1.1 3.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
1.1 3.4 GO:1903487 regulation of lactation(GO:1903487)
1.1 35.8 GO:0006337 nucleosome disassembly(GO:0006337)
1.1 3.3 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.1 3.3 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
1.1 3.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
1.1 4.4 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
1.1 5.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
1.1 2.1 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
1.0 5.2 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.0 8.2 GO:0006477 protein sulfation(GO:0006477)
1.0 18.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
1.0 10.0 GO:0035865 cellular response to potassium ion(GO:0035865)
1.0 2.0 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
1.0 3.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.0 30.3 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
1.0 2.9 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.9 2.8 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.9 6.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.9 9.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.9 5.5 GO:0006196 AMP catabolic process(GO:0006196)
0.9 11.1 GO:0043031 negative regulation of macrophage activation(GO:0043031) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.9 2.7 GO:0019376 galactolipid catabolic process(GO:0019376)
0.9 2.7 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.9 3.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.9 2.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.9 23.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.9 2.6 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.9 3.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.9 6.9 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.9 1.7 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084)
0.8 18.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.8 3.3 GO:0072166 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.8 3.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.8 9.4 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.8 8.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.8 4.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.8 2.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.7 17.9 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.7 3.7 GO:0015886 heme transport(GO:0015886)
0.7 1.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.7 3.6 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 2.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.7 12.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.7 3.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.7 2.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.7 2.0 GO:0007525 somatic muscle development(GO:0007525)
0.7 8.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.7 3.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.7 10.8 GO:0016540 protein autoprocessing(GO:0016540)
0.7 7.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.7 4.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.7 0.7 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.6 15.4 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.6 4.5 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.6 2.5 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.6 4.4 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.6 3.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.6 1.8 GO:0007538 primary sex determination(GO:0007538)
0.6 3.6 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.6 2.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.6 2.9 GO:0021997 neural plate axis specification(GO:0021997)
0.6 2.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.6 9.8 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 11.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.6 6.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.6 6.7 GO:0006069 ethanol oxidation(GO:0006069)
0.6 4.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 3.9 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.6 1.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.6 13.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.6 3.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.5 2.2 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168) positive regulation of chondrocyte proliferation(GO:1902732)
0.5 5.8 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.5 11.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.5 10.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.5 1.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 2.6 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 1.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.5 3.5 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.5 0.5 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.5 3.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.5 0.5 GO:2000405 negative regulation of T cell migration(GO:2000405)
0.5 1.4 GO:0007343 egg activation(GO:0007343)
0.5 4.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 1.8 GO:0050917 sensory perception of umami taste(GO:0050917)
0.5 9.2 GO:0035855 megakaryocyte development(GO:0035855)
0.5 3.7 GO:0070995 NADPH oxidation(GO:0070995)
0.5 1.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5 1.8 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.5 0.5 GO:0045401 interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.5 2.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.5 2.3 GO:0071895 odontoblast differentiation(GO:0071895)
0.4 1.3 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 28.1 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.4 1.7 GO:0030035 microspike assembly(GO:0030035)
0.4 16.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.4 1.3 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.4 1.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 3.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.4 3.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 30.6 GO:0019730 antimicrobial humoral response(GO:0019730)
0.4 1.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 1.2 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.4 2.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 4.9 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.4 1.9 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.4 2.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.4 9.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 3.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 2.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.0 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 1.0 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.3 2.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.3 7.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 1.3 GO:0036269 swimming behavior(GO:0036269)
0.3 19.1 GO:0032642 regulation of chemokine production(GO:0032642)
0.3 1.0 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.3 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 0.9 GO:1904387 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.3 6.2 GO:0006525 arginine metabolic process(GO:0006525)
0.3 5.2 GO:0006825 copper ion transport(GO:0006825)
0.3 12.2 GO:0018149 peptide cross-linking(GO:0018149)
0.3 3.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 8.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.3 42.3 GO:0046718 viral entry into host cell(GO:0046718)
0.3 1.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 7.3 GO:0071420 cellular response to histamine(GO:0071420)
0.3 3.7 GO:0015074 DNA integration(GO:0015074)
0.3 2.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654)
0.3 7.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.3 1.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 3.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 4.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.3 2.6 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.3 4.9 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.2 1.7 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452)
0.2 2.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 3.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 2.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 3.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 3.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.2 1.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 3.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.2 4.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 9.8 GO:0007618 mating(GO:0007618)
0.2 1.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.8 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 10.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 0.8 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.2 5.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 4.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 1.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 15.2 GO:0046849 bone remodeling(GO:0046849)
0.2 1.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 2.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 2.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 1.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 4.2 GO:0044804 nucleophagy(GO:0044804)
0.2 1.5 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.2 2.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 3.2 GO:0006833 water transport(GO:0006833)
0.2 12.0 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 2.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.8 GO:0034378 chylomicron assembly(GO:0034378)
0.2 1.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.2 8.9 GO:0016266 O-glycan processing(GO:0016266)
0.2 4.1 GO:0016246 RNA interference(GO:0016246)
0.1 8.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 4.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.0 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.1 1.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 2.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 1.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 9.4 GO:0006968 cellular defense response(GO:0006968)
0.1 1.9 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 1.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.8 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 11.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 3.0 GO:0002027 regulation of heart rate(GO:0002027)
0.1 2.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.9 GO:0001945 lymph vessel development(GO:0001945)
0.1 2.6 GO:0010039 response to iron ion(GO:0010039)
0.1 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 3.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 2.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 2.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.0 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 1.1 GO:0033189 response to vitamin A(GO:0033189)
0.1 1.5 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 7.3 GO:0070268 cornification(GO:0070268)
0.1 2.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 3.2 GO:0007099 centriole replication(GO:0007099)
0.1 4.7 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 4.6 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 3.7 GO:0042551 neuron maturation(GO:0042551)
0.1 1.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 3.3 GO:1901998 toxin transport(GO:1901998)
0.1 1.0 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 3.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 1.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 2.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.3 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) negative regulation of sister chromatid cohesion(GO:0045875) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 1.4 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 0.7 GO:0000920 cell separation after cytokinesis(GO:0000920) negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.8 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 2.4 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.7 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 1.5 GO:0033198 response to ATP(GO:0033198)
0.0 7.0 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.5 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 2.5 GO:0002687 positive regulation of leukocyte migration(GO:0002687)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.3 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 2.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.4 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 1.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 1.5 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 2.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.6 GO:0090312 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) positive regulation of protein deacetylation(GO:0090312)
0.0 2.1 GO:0007631 feeding behavior(GO:0007631)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.4 GO:0050805 negative regulation of synaptic transmission(GO:0050805)
0.0 0.5 GO:0006953 acute-phase response(GO:0006953)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 2.5 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.7 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 78.4 GO:0005833 hemoglobin complex(GO:0005833)
5.0 19.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
3.1 18.6 GO:1990584 cardiac Troponin complex(GO:1990584)
3.0 9.0 GO:0036029 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
2.6 15.4 GO:0032437 cuticular plate(GO:0032437)
2.2 6.6 GO:0097679 other organism cytoplasm(GO:0097679)
1.8 8.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.6 12.8 GO:0061689 tricellular tight junction(GO:0061689)
1.5 19.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.4 5.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.4 19.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.3 4.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.3 24.4 GO:0031089 platelet dense granule lumen(GO:0031089)
1.2 8.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.1 39.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
1.1 7.8 GO:0097209 epidermal lamellar body(GO:0097209)
1.1 9.8 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
1.1 4.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.9 7.4 GO:0045179 apical cortex(GO:0045179)
0.8 3.4 GO:0005899 insulin receptor complex(GO:0005899)
0.8 3.3 GO:0048179 activin receptor complex(GO:0048179)
0.8 4.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.7 2.2 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.7 5.5 GO:0005593 FACIT collagen trimer(GO:0005593)
0.7 24.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 5.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.6 15.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 3.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.6 13.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 8.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 2.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5 1.0 GO:0097449 astrocyte projection(GO:0097449)
0.5 4.6 GO:0042382 paraspeckles(GO:0042382)
0.5 3.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.5 1.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.5 9.9 GO:0033270 paranode region of axon(GO:0033270)
0.5 1.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.5 17.8 GO:0034451 centriolar satellite(GO:0034451)
0.5 2.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5 71.8 GO:0030863 cortical cytoskeleton(GO:0030863)
0.4 2.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 3.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 3.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 2.7 GO:0097486 late endosome lumen(GO:0031906) multivesicular body lumen(GO:0097486)
0.4 72.8 GO:0032993 protein-DNA complex(GO:0032993)
0.4 2.6 GO:0071439 clathrin complex(GO:0071439)
0.4 4.1 GO:0030061 mitochondrial crista(GO:0030061)
0.3 65.7 GO:0072562 blood microparticle(GO:0072562)
0.3 3.6 GO:0030897 HOPS complex(GO:0030897)
0.3 12.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 0.9 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.3 6.8 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.3 13.5 GO:0005796 Golgi lumen(GO:0005796)
0.3 1.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.3 3.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 3.6 GO:0031143 pseudopodium(GO:0031143)
0.3 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.3 31.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 3.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 9.7 GO:0005902 microvillus(GO:0005902)
0.2 1.0 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 2.5 GO:0070449 elongin complex(GO:0070449)
0.2 15.9 GO:0005581 collagen trimer(GO:0005581)
0.2 2.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.7 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 2.6 GO:0005922 connexon complex(GO:0005922)
0.2 3.8 GO:0032982 myosin filament(GO:0032982)
0.2 0.8 GO:1990393 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.2 2.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 26.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 2.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 2.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 4.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 4.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 11.7 GO:0035580 specific granule lumen(GO:0035580)
0.2 335.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 4.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 4.0 GO:0031526 brush border membrane(GO:0031526)
0.2 1.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 13.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 3.4 GO:0097228 sperm principal piece(GO:0097228)
0.2 214.4 GO:0005615 extracellular space(GO:0005615)
0.1 8.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 7.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 6.5 GO:0016459 myosin complex(GO:0016459)
0.1 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 15.6 GO:0055037 recycling endosome(GO:0055037)
0.1 5.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 3.2 GO:0000791 euchromatin(GO:0000791)
0.1 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.1 9.3 GO:0042383 sarcolemma(GO:0042383)
0.1 3.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 12.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 25.8 GO:0000790 nuclear chromatin(GO:0000790)
0.1 3.3 GO:0001533 cornified envelope(GO:0001533)
0.1 17.0 GO:0045177 apical part of cell(GO:0045177)
0.1 3.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 5.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.6 GO:0031904 endosome lumen(GO:0031904)
0.1 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 2.0 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.1 24.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.5 GO:0036126 sperm flagellum(GO:0036126)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 4.9 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.6 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 6.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 4.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 28.9 GO:0044432 endoplasmic reticulum part(GO:0044432)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 1.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 5.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 3.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 66.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
7.2 28.9 GO:0004341 gluconolactonase activity(GO:0004341)
6.5 19.4 GO:0004998 transferrin receptor activity(GO:0004998)
6.1 18.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
5.5 16.4 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
5.2 188.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
4.5 67.9 GO:0005344 oxygen transporter activity(GO:0005344)
4.4 13.2 GO:1902271 D3 vitamins binding(GO:1902271)
4.1 16.4 GO:0030492 hemoglobin binding(GO:0030492)
4.0 19.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
3.9 15.7 GO:0004743 pyruvate kinase activity(GO:0004743)
3.5 17.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
3.4 10.3 GO:0015265 urea channel activity(GO:0015265)
3.4 27.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.3 10.0 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
3.3 10.0 GO:0002113 interleukin-33 binding(GO:0002113)
3.0 17.9 GO:0030172 troponin C binding(GO:0030172)
2.6 7.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
2.6 7.7 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
2.5 7.4 GO:0019959 interleukin-8 binding(GO:0019959)
2.4 62.7 GO:0004806 triglyceride lipase activity(GO:0004806)
2.4 9.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
2.3 9.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.2 13.3 GO:0004882 androgen receptor activity(GO:0004882)
2.1 8.4 GO:0042015 interleukin-20 binding(GO:0042015)
2.1 6.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.8 1.8 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.8 10.5 GO:0015057 thrombin receptor activity(GO:0015057)
1.7 16.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.6 24.3 GO:0015643 toxic substance binding(GO:0015643)
1.5 7.7 GO:0016936 galactoside binding(GO:0016936)
1.5 13.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.5 7.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.5 28.3 GO:0070330 aromatase activity(GO:0070330)
1.4 5.8 GO:0004771 sterol esterase activity(GO:0004771)
1.3 4.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.3 4.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.3 19.1 GO:0019957 C-C chemokine binding(GO:0019957)
1.3 20.3 GO:0043522 leucine zipper domain binding(GO:0043522)
1.3 8.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.2 6.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.2 4.9 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.2 14.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.2 3.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
1.2 8.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.2 12.8 GO:0051525 NFAT protein binding(GO:0051525)
1.2 16.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.1 4.5 GO:0097108 hedgehog family protein binding(GO:0097108)
1.1 3.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.1 13.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.1 7.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.0 11.4 GO:0042301 phosphate ion binding(GO:0042301)
1.0 5.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
1.0 24.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.0 48.6 GO:0050699 WW domain binding(GO:0050699)
1.0 9.0 GO:0032190 acrosin binding(GO:0032190)
0.9 50.5 GO:0015485 cholesterol binding(GO:0015485)
0.9 3.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.9 2.7 GO:0004336 galactosylceramidase activity(GO:0004336)
0.9 4.5 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.9 7.9 GO:0034711 inhibin binding(GO:0034711)
0.9 4.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.8 8.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 3.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.8 2.5 GO:0005497 androgen binding(GO:0005497)
0.8 26.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.8 3.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.8 1.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.8 7.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.8 23.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.8 6.8 GO:0004969 histamine receptor activity(GO:0004969)
0.7 3.7 GO:0004803 transposase activity(GO:0004803)
0.7 3.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.7 2.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.7 8.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.7 191.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.7 3.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.7 3.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 3.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 7.1 GO:0031433 telethonin binding(GO:0031433)
0.6 2.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6 2.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 6.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 5.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 17.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 10.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.6 2.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 4.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.6 5.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.6 2.8 GO:0016841 ammonia-lyase activity(GO:0016841)
0.6 1.7 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.5 3.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 2.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.5 2.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.5 5.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.5 13.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 14.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.5 2.5 GO:0070051 fibrinogen binding(GO:0070051)
0.5 4.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.5 2.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.5 1.9 GO:0004348 glucosylceramidase activity(GO:0004348)
0.5 9.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.5 3.7 GO:0015232 heme transporter activity(GO:0015232)
0.5 1.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 3.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 2.2 GO:0019862 IgA binding(GO:0019862)
0.4 1.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 1.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.4 1.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.4 2.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.4 13.2 GO:0001972 retinoic acid binding(GO:0001972)
0.4 5.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.4 3.0 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.4 3.4 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 3.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 1.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.4 3.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 2.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 40.9 GO:0005518 collagen binding(GO:0005518)
0.3 6.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 39.8 GO:0001618 virus receptor activity(GO:0001618)
0.3 1.0 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 2.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 16.8 GO:0005272 sodium channel activity(GO:0005272)
0.3 6.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 15.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 0.9 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.3 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 0.9 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 5.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.6 GO:0048495 Roundabout binding(GO:0048495)
0.3 2.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3 2.1 GO:0004875 complement receptor activity(GO:0004875)
0.3 3.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 5.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 3.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.0 GO:0005499 vitamin D binding(GO:0005499)
0.2 6.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 7.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 3.2 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.2 20.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 20.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 4.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 1.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 6.2 GO:0001221 transcription cofactor binding(GO:0001221)
0.2 1.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 2.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 3.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 19.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 6.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 6.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 3.8 GO:0008198 ferrous iron binding(GO:0008198)
0.2 2.6 GO:0005243 gap junction channel activity(GO:0005243)
0.2 18.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.2 4.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.2 22.7 GO:0005178 integrin binding(GO:0005178)
0.2 18.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 1.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 8.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 4.1 GO:0031489 myosin V binding(GO:0031489)
0.2 2.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 4.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 15.6 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 14.3 GO:0008201 heparin binding(GO:0008201)
0.1 14.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 1.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 2.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 2.6 GO:0008483 transaminase activity(GO:0008483)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 8.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 6.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 44.9 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 6.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.9 GO:0042605 peptide antigen binding(GO:0042605)
0.1 42.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 1.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.7 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 10.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 1.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 5.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 7.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 2.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161) vascular endothelial growth factor receptor binding(GO:0005172)
0.0 2.7 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 43.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.8 60.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.7 36.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.6 154.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.6 7.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.5 7.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 3.0 PID ALK1 PATHWAY ALK1 signaling events
0.5 3.3 PID ALK2 PATHWAY ALK2 signaling events
0.3 12.9 PID IL23 PATHWAY IL23-mediated signaling events
0.3 8.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 19.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 5.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 2.1 PID IL5 PATHWAY IL5-mediated signaling events
0.2 9.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 16.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 6.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 21.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 10.9 PID EPO PATHWAY EPO signaling pathway
0.2 19.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 40.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 1.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 5.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 4.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 7.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 4.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 5.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 2.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 1.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 6.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 5.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 5.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 7.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 24.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 3.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 6.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 103.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
2.5 45.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
2.4 55.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.8 52.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.7 69.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
1.1 16.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
1.1 18.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.0 34.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.0 16.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.8 33.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 20.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.7 26.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.7 6.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 10.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 9.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 31.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.5 11.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 21.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 10.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 26.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 14.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 7.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 4.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 11.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 10.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.3 12.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 30.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 48.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 28.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 4.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 4.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 3.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 12.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 5.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 2.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 21.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 5.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 7.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 8.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 5.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.2 2.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 2.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 4.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 2.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 2.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 7.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 14.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 5.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 9.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 7.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 4.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 6.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 4.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 10.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.2 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.6 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 3.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids