Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for GCAGCAU
Z-value: 2.72
Motif logo
miRNA associated with seed GCAGCAU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-103a-3p
|
MIMAT0000101 |
|
hsa-miR-107
|
MIMAT0000104 |
Activity profile of GCAGCAU motif
Sorted Z-values of GCAGCAU motif
Network of associatons between targets according to the STRING database.
First level regulatory network of GCAGCAU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.7 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 1.5 | 4.5 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 1.4 | 5.8 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 1.4 | 5.5 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 1.2 | 3.7 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 0.8 | 1.7 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 0.8 | 2.5 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.8 | 1.6 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.8 | 2.4 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.8 | 3.0 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 0.7 | 3.0 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.7 | 5.2 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.7 | 3.7 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.7 | 2.9 | GO:0060437 | lung growth(GO:0060437) |
| 0.6 | 3.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.6 | 4.4 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.6 | 4.2 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.5 | 2.6 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.5 | 3.5 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.5 | 1.5 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.5 | 1.4 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) |
| 0.5 | 1.4 | GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) |
| 0.5 | 3.3 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.5 | 1.8 | GO:1904116 | traversing start control point of mitotic cell cycle(GO:0007089) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.4 | 1.3 | GO:0097086 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 0.4 | 2.6 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 0.4 | 2.4 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.4 | 1.1 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 0.4 | 1.1 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.4 | 1.4 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.3 | 1.7 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.3 | 1.0 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.3 | 2.7 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 1.7 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.3 | 3.9 | GO:2001140 | regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140) |
| 0.3 | 3.6 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.3 | 1.0 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.3 | 0.9 | GO:0070429 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
| 0.3 | 0.6 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.3 | 1.7 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.3 | 4.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.3 | 4.0 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.2 | 1.0 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 0.2 | 1.9 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.2 | 2.2 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 3.8 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.2 | 0.7 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 0.2 | 0.7 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.2 | 0.6 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.2 | 0.8 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.2 | 4.6 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.2 | 1.9 | GO:0060613 | fat pad development(GO:0060613) |
| 0.2 | 1.9 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.2 | 0.4 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 0.2 | 2.0 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.2 | 0.5 | GO:0009996 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) |
| 0.2 | 1.4 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.2 | 1.8 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.2 | 6.8 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.2 | 1.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.2 | 0.3 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 0.1 | 2.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.1 | 5.3 | GO:0031055 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.1 | 1.4 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.1 | 3.1 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.1 | 0.4 | GO:1903006 | flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 0.1 | 4.2 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 1.4 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 2.2 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 2.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 2.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 1.3 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 0.5 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.1 | 1.9 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.1 | 2.2 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.1 | 0.6 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 1.6 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.1 | 1.5 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.1 | 1.1 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.1 | 1.9 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 2.2 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.1 | 1.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.7 | GO:2000546 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.1 | 0.7 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.1 | 1.6 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) |
| 0.1 | 4.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 0.6 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.1 | 0.9 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 0.5 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.1 | 0.6 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.1 | 12.3 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 1.4 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 2.4 | GO:0007129 | synapsis(GO:0007129) |
| 0.1 | 3.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 0.2 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) |
| 0.1 | 0.2 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.1 | 1.7 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) |
| 0.1 | 3.3 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.1 | 3.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.4 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 2.6 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.0 | 0.2 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.0 | 1.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.0 | 0.5 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.8 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 0.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.4 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 1.7 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.3 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.0 | 0.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.2 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.0 | 0.6 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 1.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.2 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.0 | 2.4 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.0 | 0.3 | GO:0007028 | cytoplasm organization(GO:0007028) |
| 0.0 | 0.3 | GO:0044860 | protein localization to plasma membrane raft(GO:0044860) |
| 0.0 | 2.7 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 0.1 | GO:0086048 | membrane depolarization during bundle of His cell action potential(GO:0086048) |
| 0.0 | 0.1 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.0 | 0.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 3.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 1.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 1.2 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.6 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 1.5 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.1 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 0.0 | 0.1 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.1 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.0 | 0.7 | GO:0003091 | renal water homeostasis(GO:0003091) |
| 0.0 | 0.5 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.3 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.4 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.0 | 0.9 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.0 | 0.5 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 1.1 | GO:0061053 | somite development(GO:0061053) |
| 0.0 | 0.7 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 0.0 | GO:0090472 | viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 0.0 | 0.1 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.0 | 0.2 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.0 | 2.0 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 2.3 | GO:1902593 | single-organism nuclear import(GO:1902593) |
| 0.0 | 1.6 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 8.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.8 | 3.2 | GO:0035363 | histone locus body(GO:0035363) |
| 0.7 | 3.7 | GO:0005826 | actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513) |
| 0.6 | 4.4 | GO:0031415 | NatA complex(GO:0031415) |
| 0.6 | 3.0 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.6 | 1.7 | GO:0097637 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 0.5 | 2.0 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.4 | 1.3 | GO:0000805 | X chromosome(GO:0000805) |
| 0.4 | 3.8 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.3 | 5.8 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.3 | 2.6 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.3 | 1.4 | GO:0035061 | perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061) |
| 0.3 | 5.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.2 | 1.7 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.2 | 1.5 | GO:0071203 | WASH complex(GO:0071203) |
| 0.2 | 2.6 | GO:0090543 | Flemming body(GO:0090543) |
| 0.2 | 1.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.9 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 2.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 0.7 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 1.4 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 1.1 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 1.4 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 0.4 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 0.1 | 17.5 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 2.3 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 7.1 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 0.5 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 4.2 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.1 | 7.5 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 0.9 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 5.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 2.2 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 6.0 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.1 | 3.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 0.5 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 1.8 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 0.3 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.1 | 3.4 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 0.5 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.1 | 3.4 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 1.7 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.1 | 0.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 1.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 2.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 4.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.4 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.8 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 2.5 | GO:1902554 | serine/threonine protein kinase complex(GO:1902554) |
| 0.0 | 0.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 3.5 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 2.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 1.2 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 6.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.2 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 0.3 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.0 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.0 | 1.5 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 1.0 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 2.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 4.2 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 1.6 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.7 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 4.7 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.6 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 1.6 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.1 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 7.6 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.9 | 5.8 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 1.7 | 5.2 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 1.4 | 5.5 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 1.3 | 3.9 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 1.2 | 3.5 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.6 | 7.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.6 | 3.0 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.6 | 6.6 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.5 | 1.6 | GO:0047756 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756) |
| 0.5 | 2.1 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.5 | 1.4 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 0.4 | 5.8 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.4 | 1.9 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.4 | 1.1 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.4 | 1.4 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.3 | 1.4 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.3 | 2.7 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 1.7 | GO:0032558 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.3 | 4.4 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.3 | 1.9 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.3 | 1.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.3 | 2.5 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.3 | 1.7 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.3 | 4.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.3 | 3.5 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.3 | 3.8 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.2 | 1.0 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.2 | 3.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.2 | 2.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.2 | 0.6 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.2 | 0.8 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.2 | 2.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.2 | 8.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 0.6 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.2 | 4.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.2 | 2.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.2 | 0.6 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.2 | 3.7 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 1.3 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.1 | 0.8 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 0.9 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 2.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 1.5 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.1 | 1.7 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 5.1 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 1.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 1.7 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 1.0 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.1 | 0.9 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 4.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 4.3 | GO:0043175 | RNA polymerase core enzyme binding(GO:0043175) |
| 0.1 | 1.2 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.1 | 4.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 2.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 0.7 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.1 | 0.4 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.1 | 1.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 1.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 0.4 | GO:1904288 | deubiquitinase activator activity(GO:0035800) BAT3 complex binding(GO:1904288) |
| 0.1 | 1.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 0.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 5.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 0.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 2.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 0.2 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.1 | 2.6 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 0.6 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 1.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 3.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 1.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 0.3 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.0 | 0.5 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 0.1 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 0.7 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 3.5 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 2.0 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.0 | 1.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.8 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 0.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 3.0 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.6 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 1.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.6 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.3 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.0 | 0.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 1.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 7.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.1 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 0.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.2 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 2.5 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 1.2 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.2 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 2.0 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.4 | GO:0042605 | peptide antigen binding(GO:0042605) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.9 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 13.0 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 2.4 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 3.8 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.1 | 1.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 2.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 1.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 5.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 1.8 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 1.9 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 1.0 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 3.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 4.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 4.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 2.2 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.8 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 3.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 2.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.6 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 1.1 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 2.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.2 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 0.3 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 1.0 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.8 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.8 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.4 | 8.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.3 | 5.8 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 5.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.2 | 8.4 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.1 | 1.0 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 2.8 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.1 | 1.8 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.1 | 3.6 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.1 | 1.4 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 2.3 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.1 | 1.6 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.1 | 3.2 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 2.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.0 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 1.0 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 4.1 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 3.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 2.7 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 2.4 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 1.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 3.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 1.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 3.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.9 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 1.7 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.1 | 3.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 1.5 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 1.4 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 1.4 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 1.1 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 6.1 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 1.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.0 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 1.2 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 2.6 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 7.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.8 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.7 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.1 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 1.5 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |