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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GCM1

Z-value: 3.43

Motif logo

Transcription factors associated with GCM1

Gene Symbol Gene ID Gene Info
ENSG00000137270.11 GCM1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM1hg38_v1_chr6_-_53148822_531488460.144.0e-02Click!

Activity profile of GCM1 motif

Sorted Z-values of GCM1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_10164883 32.60 ENST00000256458.5
interleukin 1 receptor associated kinase 2
chr22_+_22822658 22.87 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr22_+_22758698 21.54 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr22_+_22734577 20.27 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr2_+_90069662 20.26 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr22_+_22588155 19.79 ENST00000390302.3
immunoglobulin lambda variable 2-33 (non-functional)
chr2_-_89160329 19.71 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr2_+_90021567 19.70 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr2_-_89330429 19.24 ENST00000620613.1
immunoglobulin kappa variable 2-40
chr22_+_22697789 17.74 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_+_22327298 17.17 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr22_+_22792485 15.58 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr17_-_15999689 15.56 ENST00000399277.6
zinc finger SWIM-type containing 7
chr2_+_90159840 13.27 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr2_-_136118142 12.75 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr6_-_109440504 11.20 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr22_+_22431949 11.03 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr22_+_22380766 10.68 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr22_+_22322452 10.47 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr8_+_140511286 10.17 ENST00000519533.1
ENST00000220913.10
chromatin accessibility complex subunit 1
chr22_+_22594528 10.00 ENST00000390303.3
immunoglobulin lambda variable 3-32 (non-functional)
chr19_-_12551426 9.66 ENST00000416136.1
ENST00000339282.12
ENST00000596193.1
ENST00000428311.1
zinc finger protein 564
novel zinc finger protein
chr4_+_186191549 9.57 ENST00000378802.5
cytochrome P450 family 4 subfamily V member 2
chr22_+_22811737 9.33 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr17_-_3696133 8.41 ENST00000225328.10
purinergic receptor P2X 5
chr17_-_3696033 8.29 ENST00000551178.5
ENST00000552276.5
ENST00000547178.5
purinergic receptor P2X 5
chr17_-_3696198 8.11 ENST00000345901.7
purinergic receptor P2X 5
chr22_+_22409755 7.95 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr6_+_42050513 7.90 ENST00000372978.7
ENST00000494547.5
ENST00000456846.6
ENST00000372982.8
ENST00000472818.5
ENST00000372977.8
TATA-box binding protein associated factor 8
chr16_+_19718264 6.63 ENST00000564186.5
IQ motif containing K
chr10_+_102918344 6.39 ENST00000433628.2
cyclin and CBS domain divalent metal cation transport mediator 2
chr3_-_46464868 6.13 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chr10_+_102918276 5.74 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chr9_-_35650902 5.74 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr7_-_152676130 5.65 ENST00000359321.2
X-ray repair cross complementing 2
chr4_-_5893075 5.10 ENST00000324989.12
collapsin response mediator protein 1
chr3_+_38039199 4.94 ENST00000346219.7
ENST00000308059.11
DLEC1 cilia and flagella associated protein
chr2_+_234050732 4.87 ENST00000425558.1
secreted phosphoprotein 2
chr11_-_64744102 4.80 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RAS guanyl releasing protein 2
chr1_+_161215242 4.71 ENST00000367992.7
ENST00000289902.2
Fc fragment of IgE receptor Ig
chr1_-_11848345 4.69 ENST00000376476.1
natriuretic peptide A
chr6_-_30075767 4.58 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr7_-_100656384 4.55 ENST00000461605.1
ENST00000160382.10
actin like 6B
chr7_-_130440848 4.53 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr14_+_39267377 4.48 ENST00000556148.5
ENST00000348007.7
MIA SH3 domain ER export factor 2
chr2_+_111120906 4.45 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr11_+_17734732 4.35 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr5_-_180649579 4.31 ENST00000261937.11
ENST00000502649.5
fms related receptor tyrosine kinase 4
chr9_-_120929160 4.30 ENST00000540010.1
TNF receptor associated factor 1
chr22_+_22686724 4.26 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr16_+_3065610 4.25 ENST00000530890.5
ENST00000444393.7
ENST00000533097.6
ENST00000008180.13
ENST00000396890.6
ENST00000525228.5
ENST00000525643.7
ENST00000548652.5
ENST00000525377.6
ENST00000530538.6
ENST00000549213.5
ENST00000552936.5
ENST00000548476.5
ENST00000552664.5
ENST00000552356.5
ENST00000551513.5
ENST00000382213.7
ENST00000548246.1
interleukin 32
chr5_-_134367144 4.23 ENST00000265334.9
cyclin dependent kinase like 3
chr16_-_21159441 4.14 ENST00000261383.3
dynein axonemal heavy chain 3
chr19_+_11547840 4.12 ENST00000588935.1
calponin 1
chr19_+_54200849 4.08 ENST00000626547.2
ENST00000302907.9
ENST00000391752.5
ENST00000402367.5
ENST00000391751.7
ribosomal protein S9
chr1_-_11847772 4.02 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr10_-_103918128 3.91 ENST00000224950.8
STN1 subunit of CST complex
chr3_-_47513303 3.91 ENST00000449409.5
ENST00000414236.5
ENST00000444760.5
ENST00000439305.5
elongator acetyltransferase complex subunit 6
chr5_-_134367070 3.90 ENST00000521118.5
cyclin dependent kinase like 3
chr11_-_64744317 3.83 ENST00000419843.1
ENST00000394430.5
RAS guanyl releasing protein 2
chr11_-_8168987 3.71 ENST00000425599.6
ENST00000531450.1
ENST00000309737.11
ENST00000419822.2
ENST00000335425.7
ENST00000343202.8
RIC3 acetylcholine receptor chaperone
chr10_+_129467178 3.60 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr2_+_950836 3.59 ENST00000308624.10
ENST00000407292.1
syntrophin gamma 2
chr15_-_60592507 3.51 ENST00000449337.6
RAR related orphan receptor A
chr20_+_38317627 3.46 ENST00000417318.3
bactericidal permeability increasing protein
chr7_-_144269288 3.46 ENST00000487179.1
CTAGE family member 8
chr12_-_6556034 3.41 ENST00000619571.5
ENST00000336604.8
ENST00000396840.6
ENST00000356896.8
intermediate filament family orphan 1
chr16_-_57479745 3.37 ENST00000566936.5
ENST00000568617.5
ENST00000567276.5
ENST00000569548.5
ENST00000569250.5
ENST00000564378.5
docking protein 4
chr9_-_101383558 3.35 ENST00000674556.1
bile acid-CoA:amino acid N-acyltransferase
chr19_+_12791470 3.31 ENST00000302754.6
JunB proto-oncogene, AP-1 transcription factor subunit
chr5_-_170297746 3.28 ENST00000046794.10
lymphocyte cytosolic protein 2
chr16_-_23510389 3.26 ENST00000562117.1
ENST00000567468.5
ENST00000562944.5
ENST00000309859.8
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr17_-_44503369 3.17 ENST00000585614.1
ENST00000591680.6
G-patch domain containing 8
chr12_+_11649666 3.16 ENST00000396373.9
ETS variant transcription factor 6
chr20_+_2873420 3.15 ENST00000455631.5
ENST00000399903.7
ENST00000216877.10
ENST00000431048.5
ENST00000430705.5
ENST00000318266.9
protein tyrosine phosphatase receptor type A
chr7_-_50093204 3.15 ENST00000419417.5
ENST00000046087.7
zona pellucida binding protein
chr16_+_53434430 3.06 ENST00000262133.11
RB transcriptional corepressor like 2
chr15_+_83107572 3.06 ENST00000379390.10
ENST00000322019.14
ENST00000565774.5
ENST00000565982.1
transmembrane 6 superfamily member 1
chr16_+_3065380 2.99 ENST00000551122.5
ENST00000548807.5
ENST00000528163.6
interleukin 32
chr10_+_72215981 2.97 ENST00000615507.4
ENST00000621663.4
ENST00000299381.5
anaphase promoting complex subunit 16
chrX_+_35798791 2.96 ENST00000399985.1
MAGE family member B16
chr22_+_22195753 2.94 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr21_-_44240840 2.92 ENST00000344330.8
ENST00000407780.7
ENST00000400379.7
ENST00000400377.3
inducible T cell costimulator ligand
chr9_-_133129395 2.88 ENST00000393157.8
ral guanine nucleotide dissociation stimulator
chr16_+_67029359 2.87 ENST00000565389.1
core-binding factor subunit beta
chr14_+_39267055 2.81 ENST00000396158.6
ENST00000280083.7
ENST00000341502.9
MIA SH3 domain ER export factor 2
chr9_-_96778053 2.81 ENST00000375231.5
ENST00000223428.9
zinc finger protein 510
chr19_+_49474208 2.79 ENST00000597551.6
ENST00000596435.5
ENST00000204637.6
ENST00000600429.5
fms related receptor tyrosine kinase 3 ligand
chr19_-_38315919 2.78 ENST00000591755.5
ENST00000337679.12
ENST00000339413.11
Yip1 interacting factor homolog B, membrane trafficking protein
chr3_-_99876104 2.77 ENST00000471562.1
ENST00000495625.2
filamin A interacting protein 1 like
chr9_+_114611206 2.70 ENST00000374049.4
ENST00000288502.9
transmembrane protein 268
chr17_-_45490696 2.63 ENST00000430334.8
ENST00000584420.1
ENST00000589780.5
pleckstrin homology and RUN domain containing M1
chr14_-_22815856 2.61 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr15_-_78641200 2.61 ENST00000261751.8
cholinergic receptor nicotinic beta 4 subunit
chr19_+_54201122 2.61 ENST00000391753.6
ENST00000441429.1
ribosomal protein S9
chr18_+_70288991 2.57 ENST00000397942.4
suppressor of cytokine signaling 6
chr6_+_42960742 2.55 ENST00000372808.4
glycine N-methyltransferase
chr17_-_8079903 2.55 ENST00000649809.1
arachidonate 12-lipoxygenase, 12R type
chr10_-_74150781 2.54 ENST00000355264.9
ENST00000372745.1
adaptor related protein complex 3 subunit mu 1
chr6_-_131711017 2.53 ENST00000314099.10
CTAGE family member 9
chr4_+_55346213 2.39 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr22_-_37580075 2.38 ENST00000215886.6
galectin 2
chr19_+_49474561 2.38 ENST00000594009.5
ENST00000595510.1
ENST00000595815.1
fms related receptor tyrosine kinase 3 ligand
novel transcript
chr8_+_141128581 2.37 ENST00000519811.6
DENN domain containing 3
chr7_-_4862015 2.36 ENST00000404991.2
poly(A) polymerase beta
chr3_-_9952337 2.35 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr4_-_118352967 2.31 ENST00000296498.3
serine protease 12
chr8_+_141128612 2.27 ENST00000518347.5
ENST00000262585.6
ENST00000520986.5
ENST00000523058.5
ENST00000518668.5
DENN domain containing 3
chr22_+_41800662 2.26 ENST00000402061.7
ENST00000255784.6
coiled-coil domain containing 134
chr7_-_143757696 2.25 ENST00000470691.2
CTAGE family member 6
chr9_-_119369416 2.22 ENST00000373964.2
ENST00000265922.8
BMP/retinoic acid inducible neural specific 1
chr17_-_7590072 2.21 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SRY-box transcription factor 15
chr9_+_34958254 2.20 ENST00000242315.3
PHD finger protein 24
chr10_+_119029711 2.19 ENST00000425699.3
nanos C2HC-type zinc finger 1
chr3_-_10708007 2.16 ENST00000646379.1
ATPase plasma membrane Ca2+ transporting 2
chr12_-_4445810 2.16 ENST00000228837.3
fibroblast growth factor 6
chr2_+_112482133 2.14 ENST00000233336.7
tubulin tyrosine ligase
chr11_-_75490725 2.13 ENST00000529721.5
glycerophosphodiester phosphodiesterase domain containing 5
chr10_-_103917657 2.10 ENST00000369764.1
STN1 subunit of CST complex
chr5_+_178895892 2.08 ENST00000520660.5
ENST00000361362.7
ENST00000520805.5
ZFP2 zinc finger protein
chr19_-_821929 2.08 ENST00000359894.6
ENST00000520876.8
ENST00000519502.2
phospholipid phosphatase related 3
chr15_+_41828085 2.07 ENST00000397299.9
ENST00000408047.5
ENST00000431823.1
ENST00000382448.8
ENST00000342159.6
jumonji domain containing 7
JMJD7-PLA2G4B readthrough
chr17_+_42761218 2.06 ENST00000253796.10
receptor activity modifying protein 2
chr6_+_109691249 2.02 ENST00000675726.1
ENST00000674933.1
ENST00000676442.1
ENST00000674744.1
ENST00000675606.1
ENST00000675523.1
ENST00000675714.1
ENST00000368941.2
ENST00000454215.6
ENST00000676435.1
ENST00000674644.1
ENST00000675284.1
ENST00000674641.1
ENST00000230124.8
ENST00000675772.1
ENST00000675973.1
ENST00000675681.1
ENST00000675096.1
ENST00000675831.1
ENST00000674884.1
ENST00000415980.2
FIG4 phosphoinositide 5-phosphatase
chr11_-_63015831 2.00 ENST00000430500.6
ENST00000336232.7
solute carrier family 22 member 8
chr2_-_24360299 1.97 ENST00000361999.7
intersectin 2
chr17_+_42761246 1.97 ENST00000587142.5
ENST00000588576.1
receptor activity modifying protein 2
chr11_-_63015804 1.95 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chr1_-_8423664 1.94 ENST00000476556.5
arginine-glutamic acid dipeptide repeats
chr2_+_108449178 1.92 ENST00000309863.11
ENST00000409821.5
GRIP and coiled-coil domain containing 2
chr2_+_148947868 1.91 ENST00000679129.1
kinesin family member 5C
chr5_+_141373878 1.88 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr16_-_70685975 1.87 ENST00000338779.11
MTSS I-BAR domain containing 2
chr1_-_235588959 1.86 ENST00000484517.2
G protein subunit gamma 4
chr16_+_10877181 1.85 ENST00000618207.4
ENST00000618327.4
ENST00000324288.14
ENST00000381835.9
class II major histocompatibility complex transactivator
chr5_-_180649613 1.84 ENST00000393347.7
ENST00000619105.4
fms related receptor tyrosine kinase 4
chr12_+_32399517 1.83 ENST00000534526.7
FYVE, RhoGEF and PH domain containing 4
chrX_-_64395417 1.83 ENST00000374852.4
myotubularin related protein 8
chr7_-_137343688 1.78 ENST00000348225.7
pleiotrophin
chr17_+_45784314 1.72 ENST00000314537.10
corticotropin releasing hormone receptor 1
chr16_-_70685791 1.70 ENST00000616026.4
MTSS I-BAR domain containing 2
chr22_-_32202451 1.64 ENST00000248983.8
ret finger protein like 2
chr17_+_45784265 1.61 ENST00000293493.11
ENST00000339069.9
ENST00000619154.4
corticotropin releasing hormone receptor 1
chr2_-_127106961 1.58 ENST00000376113.6
bridging integrator 1
chr15_+_45129933 1.56 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr15_+_78340344 1.56 ENST00000299529.7
cellular retinoic acid binding protein 1
chr19_-_6379058 1.55 ENST00000597721.1
persephin
chr11_-_35418966 1.43 ENST00000531628.2
solute carrier family 1 member 2
chr17_-_28897602 1.43 ENST00000394906.6
ENST00000585169.5
flotillin 2
chr3_+_46407251 1.38 ENST00000399036.4
C-C motif chemokine receptor like 2
chr1_+_23743462 1.37 ENST00000609199.1
elongin A
chr8_-_132111159 1.37 ENST00000673615.1
ENST00000434736.6
HERV-H LTR-associating 1
chr2_-_113235443 1.33 ENST00000465084.1
paired box 8
chr7_-_712437 1.28 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr4_+_4387078 1.28 ENST00000504171.1
neuronal vesicle trafficking associated 1
chr8_-_81841958 1.25 ENST00000519817.5
ENST00000521773.5
ENST00000523757.5
ENST00000345957.9
sorting nexin 16
chr15_-_78641225 1.24 ENST00000412074.6
cholinergic receptor nicotinic beta 4 subunit
chr11_+_124865425 1.22 ENST00000397801.6
roundabout guidance receptor 3
chr4_+_109827963 1.20 ENST00000317735.7
retinal pigment epithelium-derived rhodopsin homolog
chr1_+_159005953 1.18 ENST00000426592.6
interferon gamma inducible protein 16
chr11_-_47449129 1.14 ENST00000298854.7
ENST00000524487.5
ENST00000529341.1
ENST00000352508.7
receptor associated protein of the synapse
chr1_-_68449927 1.14 ENST00000262340.6
retinoid isomerohydrolase RPE65
chr9_+_17579059 0.98 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr19_-_12775513 0.97 ENST00000397668.8
ENST00000587178.1
ENST00000264827.9
hook microtubule tethering protein 2
chr3_+_193241190 0.97 ENST00000264735.4
phospholipase A and acyltransferase 1
chr2_+_234050679 0.93 ENST00000373368.5
ENST00000168148.8
secreted phosphoprotein 2
chr3_+_186666003 0.92 ENST00000232003.5
histidine rich glycoprotein
chr1_+_1280588 0.90 ENST00000338555.6
sodium channel epithelial 1 subunit delta
chr22_+_22375984 0.89 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr17_+_42854078 0.87 ENST00000591562.1
ENST00000588033.1
amine oxidase copper containing 3
chr4_+_8592750 0.86 ENST00000315782.6
ENST00000360986.9
carboxypeptidase Z
chr1_-_44031352 0.82 ENST00000372306.7
ENST00000475075.6
solute carrier family 6 member 9
chr5_-_41870416 0.74 ENST00000196371.10
3-oxoacid CoA-transferase 1
chr1_+_17308194 0.71 ENST00000375453.5
ENST00000375448.4
peptidyl arginine deiminase 4
chr4_+_75724569 0.70 ENST00000514213.7
ENST00000264904.8
USO1 vesicle transport factor
chr1_-_44031446 0.69 ENST00000372310.8
ENST00000466926.1
solute carrier family 6 member 9
chr18_+_10526011 0.67 ENST00000322897.11
NSF attachment protein gamma
chr19_+_48373043 0.65 ENST00000600863.5
ENST00000601610.5
ENST00000595322.1
synaptogyrin 4
chr19_-_40090860 0.64 ENST00000599972.1
ENST00000450241.6
ENST00000595687.6
ENST00000340963.9
zinc finger protein 780A
chr7_-_137343752 0.63 ENST00000393083.2
pleiotrophin
chr7_+_7566866 0.61 ENST00000405785.5
ENST00000340080.9
ENST00000433635.1
meiosis regulator for oocyte development
chr14_-_24263162 0.58 ENST00000206765.11
ENST00000544573.5
transglutaminase 1
chr1_+_23743153 0.58 ENST00000418390.6
elongin A
chr19_+_35031263 0.57 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr3_-_99876193 0.57 ENST00000383694.3
filamin A interacting protein 1 like
chr2_+_189784435 0.56 ENST00000409985.5
ENST00000441310.7
ENST00000446877.5
ENST00000409823.7
ENST00000374826.8
ENST00000424766.5
ENST00000447232.6
PMS1 homolog 1, mismatch repair system component
chr11_-_35419098 0.56 ENST00000606205.6
ENST00000645303.1
solute carrier family 1 member 2
chr3_-_48595267 0.54 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr2_-_171066936 0.53 ENST00000453628.1
ENST00000434911.6
tousled like kinase 1
chr8_+_22042790 0.52 ENST00000359441.4
fibroblast growth factor 17
chr3_+_40505992 0.48 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
zinc finger protein 620
chr5_+_177357834 0.47 ENST00000408923.8
regulator of G protein signaling 14
chr9_+_68705230 0.46 ENST00000265382.8
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr6_+_157981826 0.45 ENST00000355585.9
ENST00000640338.1
ENST00000367113.5
synaptojanin 2
chr1_+_23743366 0.35 ENST00000613537.4
elongin A
chr1_-_13198130 0.34 ENST00000638454.1
PRAME family member 13
chr16_+_72108296 0.33 ENST00000563819.5
ENST00000567142.2
DEAH-box helicase 38
chr2_-_112434488 0.33 ENST00000409750.5
RANBP2 like and GRIP domain containing 8
chr16_+_8621679 0.32 ENST00000563958.5
ENST00000381920.8
ENST00000564554.1
methyltransferase like 22
chr15_+_90903288 0.32 ENST00000559717.6
mannosidase alpha class 2A member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.7 5.1 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.7 6.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.6 4.7 GO:0001812 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type I hypersensitivity(GO:0001812) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
1.5 6.1 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
1.5 4.5 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
1.5 8.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.5 4.4 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
1.4 32.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
1.3 5.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
1.3 12.8 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.9 5.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.9 127.3 GO:0030449 regulation of complement activation(GO:0030449)
0.8 148.4 GO:0002377 immunoglobulin production(GO:0002377)
0.8 24.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.8 2.4 GO:1904397 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.7 12.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.7 7.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.6 4.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.6 3.9 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.6 1.9 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.6 2.4 GO:0016095 polyprenol catabolic process(GO:0016095)
0.6 2.2 GO:0048627 myoblast development(GO:0048627)
0.5 1.6 GO:0060988 lipid tube assembly(GO:0060988)
0.5 3.2 GO:0007296 vitellogenesis(GO:0007296)
0.5 1.6 GO:0034653 isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.5 6.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.5 1.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 3.3 GO:0051458 corticosterone secretion(GO:0035934) corticotropin secretion(GO:0051458) regulation of corticosterone secretion(GO:2000852)
0.4 4.0 GO:0097647 vascular smooth muscle cell development(GO:0097084) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 2.6 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.3 1.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.3 3.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 2.5 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.3 0.9 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 3.6 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.3 4.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 3.5 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.3 3.3 GO:0019530 taurine metabolic process(GO:0019530)
0.3 1.9 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.2 3.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 4.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2 8.1 GO:0030517 negative regulation of axon extension(GO:0030517)
0.2 6.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.2 0.8 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.2 1.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.2 0.7 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 2.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 1.4 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.2 5.7 GO:0043029 T cell homeostasis(GO:0043029)
0.1 2.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 1.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 1.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 2.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.6 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.1 2.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 2.5 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 10.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 2.2 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 6.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 1.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 2.9 GO:0006972 hyperosmotic response(GO:0006972)
0.1 3.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.6 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.1 0.7 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 4.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 3.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.2 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 2.2 GO:0001502 cartilage condensation(GO:0001502)
0.1 3.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 5.8 GO:0046849 bone remodeling(GO:0046849)
0.1 3.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 18.5 GO:0002250 adaptive immune response(GO:0002250)
0.0 9.9 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 4.5 GO:0021510 spinal cord development(GO:0021510)
0.0 2.4 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 2.6 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 1.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.2 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 4.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 3.3 GO:0050663 cytokine secretion(GO:0050663)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 3.2 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.9 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 2.3 GO:0031638 zymogen activation(GO:0031638)
0.0 2.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 14.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 3.9 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0008623 CHRAC(GO:0008623)
1.5 6.0 GO:1990879 CST complex(GO:1990879)
1.2 24.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
1.0 6.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.9 5.6 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 3.3 GO:0036398 TCR signalosome(GO:0036398)
0.5 1.6 GO:0060987 lipid tube(GO:0060987)
0.5 4.0 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.4 3.3 GO:0035976 AP1 complex(GO:0035976)
0.4 4.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 3.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 4.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.3 3.6 GO:0016013 syntrophin complex(GO:0016013)
0.3 5.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 16.1 GO:1990391 DNA repair complex(GO:1990391)
0.3 7.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 1.0 GO:0070695 FHF complex(GO:0070695)
0.2 8.7 GO:0042629 mast cell granule(GO:0042629)
0.2 2.3 GO:0070449 elongin complex(GO:0070449)
0.2 4.6 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 7.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 5.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 2.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.3 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 6.3 GO:0030673 axolemma(GO:0030673)
0.1 1.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 4.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 2.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 5.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 3.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 12.8 GO:0005770 late endosome(GO:0005770)
0.1 6.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.9 GO:0005903 brush border(GO:0005903)
0.1 170.5 GO:0005615 extracellular space(GO:0005615)
0.1 1.1 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 2.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 3.5 GO:0035580 specific granule lumen(GO:0035580)
0.1 3.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 32.5 GO:0010008 endosome membrane(GO:0010008)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 4.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 15.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0001772 immunological synapse(GO:0001772)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 4.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 9.3 GO:0043235 receptor complex(GO:0043235)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 74.9 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 24.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.3 12.8 GO:0032027 myosin light chain binding(GO:0032027)
1.1 3.3 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
1.0 6.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.9 4.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 216.7 GO:0003823 antigen binding(GO:0003823)
0.8 3.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.8 2.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.7 11.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 1.9 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.6 2.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.6 3.5 GO:0008142 oxysterol binding(GO:0008142)
0.5 3.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 6.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 2.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.5 4.0 GO:0097643 amylin receptor activity(GO:0097643)
0.5 2.4 GO:0016936 galactoside binding(GO:0016936)
0.4 2.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 8.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 1.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 5.6 GO:0000150 recombinase activity(GO:0000150)
0.3 10.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 2.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 6.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.3 3.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 9.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 2.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 4.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 4.3 GO:0031996 thioesterase binding(GO:0031996)
0.2 8.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 5.1 GO:0031005 filamin binding(GO:0031005)
0.2 2.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 3.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 4.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.8 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 0.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 4.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 2.6 GO:0016594 glycine binding(GO:0016594)
0.1 0.7 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 2.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 2.1 GO:0042577 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.1 3.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 3.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 2.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 6.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 5.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 4.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.6 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 2.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.6 GO:0048156 tau protein binding(GO:0048156)
0.1 4.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 9.6 GO:0004497 monooxygenase activity(GO:0004497)
0.1 3.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.1 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 3.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.2 GO:0030371 translation repressor activity(GO:0030371)
0.1 5.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 38.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 1.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 2.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.4 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 7.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 6.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 4.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 4.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 9.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 32.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 6.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 12.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 4.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 3.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 8.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 3.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 2.4 PID FGF PATHWAY FGF signaling pathway
0.0 3.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 6.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.6 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 32.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
2.1 12.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.4 6.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 3.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 4.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 8.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 8.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 3.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 3.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 4.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 3.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 2.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 6.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 2.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.2 REACTOME OPSINS Genes involved in Opsins
0.1 3.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 3.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 4.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 4.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 4.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 4.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 10.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 3.6 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation