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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GCUGGUG

Z-value: 1.14

Motif logo

logo of

miRNA associated with seed GCUGGUG

NamemiRBASE accession
hsa-miR-138-5p
MIMAT0000430

Activity profile of GCUGGUG motif

Sorted Z-values of GCUGGUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_10218808 10.92 ENST00000254976.7
ENST00000304886.6
SNAP25
synaptosome associated protein 25
chr5_-_176630364 6.69 ENST00000310112.7
SNCB
synuclein beta
chr19_-_49441508 6.48 ENST00000221485.8
SLC17A7
solute carrier family 17 member 7
chr3_-_12967668 6.13 ENST00000273221.8
IQSEC1
IQ motif and Sec7 domain ArfGEF 1
chr6_-_46325641 5.92 ENST00000330430.10
ENST00000405162.2
RCAN2
regulator of calcineurin 2
chr17_-_80476597 5.11 ENST00000306773.5
NPTX1
neuronal pentraxin 1
chr1_-_40665654 4.86 ENST00000372684.8
RIMS3
regulating synaptic membrane exocytosis 3
chr4_+_47031551 4.62 ENST00000295454.8
GABRB1
gamma-aminobutyric acid type A receptor subunit beta1
chr7_-_103989649 4.30 ENST00000428762.6
RELN
reelin
chr9_+_17579059 4.18 ENST00000380607.5
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1
chr17_-_10026265 3.90 ENST00000437099.6
ENST00000396115.6
GAS7
growth arrest specific 7
chr16_-_57284654 3.87 ENST00000613167.4
ENST00000219207.10
ENST00000569059.5
PLLP
plasmolipin
chr1_-_20486197 3.82 ENST00000375078.4
CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
chr6_+_107490103 3.65 ENST00000317357.10
SOBP
sine oculis binding protein homolog
chr11_-_123654581 3.42 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
SCN3B
sodium voltage-gated channel beta subunit 3
chr6_+_39792993 3.36 ENST00000538976.5
DAAM2
dishevelled associated activator of morphogenesis 2
chr18_-_55588184 3.27 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr7_+_155458129 3.20 ENST00000297375.4
EN2
engrailed homeobox 2
chr20_+_56358938 3.11 ENST00000371384.4
ENST00000437418.1
FAM210B
family with sequence similarity 210 member B
chr2_+_86720282 3.09 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chr4_-_2262082 2.98 ENST00000337190.7
MXD4
MAX dimerization protein 4
chr6_-_41941795 2.95 ENST00000372991.9
CCND3
cyclin D3
chr2_-_73269483 2.93 ENST00000295133.9
FBXO41
F-box protein 41
chr3_-_9249623 2.84 ENST00000383836.8
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr6_+_34792056 2.66 ENST00000192788.6
UHRF1BP1
UHRF1 binding protein 1
chr22_-_45240859 2.64 ENST00000336156.10
KIAA0930
KIAA0930
chr11_-_75351609 2.39 ENST00000420843.7
ARRB1
arrestin beta 1
chr5_+_176365455 2.31 ENST00000310389.6
ARL10
ADP ribosylation factor like GTPase 10
chr17_-_4263847 2.30 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr17_-_17972374 2.19 ENST00000318094.14
ENST00000540946.5
ENST00000379504.8
ENST00000542206.5
ENST00000395739.8
ENST00000581396.5
ENST00000535933.5
ENST00000579586.1
TOM1L2
target of myb1 like 2 membrane trafficking protein
chr2_-_239400949 2.16 ENST00000345617.7
HDAC4
histone deacetylase 4
chr8_+_22604632 2.15 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
CCAR2
cell cycle and apoptosis regulator 2
chr15_-_43584864 2.14 ENST00000381885.5
ENST00000396923.7
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_-_149917826 2.09 ENST00000369145.1
ENST00000369146.8
SV2A
synaptic vesicle glycoprotein 2A
chr10_+_69318831 1.97 ENST00000359426.7
HK1
hexokinase 1
chr9_-_128771909 1.97 ENST00000291900.7
ENST00000414921.5
ZER1
zyg-11 related cell cycle regulator
chr19_-_2783241 1.96 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr2_-_43226594 1.96 ENST00000282388.4
ZFP36L2
ZFP36 ring finger protein like 2
chr3_+_47282930 1.93 ENST00000232766.6
ENST00000437353.5
KLHL18
kelch like family member 18
chr19_+_3880647 1.90 ENST00000450849.7
ATCAY
ATCAY kinesin light chain interacting caytaxin
chr3_-_115071333 1.85 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_181680490 1.84 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
CERKL
NEUROD1
ceramide kinase like
neuronal differentiation 1
chr1_+_26529745 1.84 ENST00000374168.7
ENST00000374166.8
RPS6KA1
ribosomal protein S6 kinase A1
chr10_+_102714595 1.78 ENST00000602647.5
ENST00000602439.5
ENST00000602764.5
ENST00000369893.10
SFXN2
sideroflexin 2
chr20_+_33490073 1.77 ENST00000342704.11
ENST00000375279.6
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr5_-_116574802 1.77 ENST00000343348.11
SEMA6A
semaphorin 6A
chrX_-_53225176 1.76 ENST00000404049.7
ENST00000375401.8
KDM5C
lysine demethylase 5C
chr19_-_344786 1.75 ENST00000264819.7
MIER2
MIER family member 2
chr3_-_57693045 1.75 ENST00000311128.10
DENND6A
DENN domain containing 6A
chr8_-_41797589 1.75 ENST00000347528.8
ENST00000289734.13
ANK1
ankyrin 1
chr22_+_38705922 1.73 ENST00000216044.10
GTPBP1
GTP binding protein 1
chr2_-_100417608 1.73 ENST00000264249.8
CHST10
carbohydrate sulfotransferase 10
chr11_-_45286265 1.72 ENST00000020926.8
SYT13
synaptotagmin 13
chr7_-_29989774 1.71 ENST00000242059.10
SCRN1
secernin 1
chr16_-_29899043 1.63 ENST00000346932.9
ENST00000350527.7
ENST00000568380.1
SEZ6L2
seizure related 6 homolog like 2
chr3_-_142448060 1.62 ENST00000264951.8
XRN1
5'-3' exoribonuclease 1
chr13_+_42272134 1.59 ENST00000025301.4
AKAP11
A-kinase anchoring protein 11
chr19_-_14206168 1.58 ENST00000361434.7
ENST00000340736.10
ADGRL1
adhesion G protein-coupled receptor L1
chr12_+_111405861 1.58 ENST00000341259.7
SH2B3
SH2B adaptor protein 3
chr12_+_131711072 1.56 ENST00000261674.9
ENST00000541286.5
SFSWAP
splicing factor SWAP
chr7_+_90596281 1.51 ENST00000380050.8
CDK14
cyclin dependent kinase 14
chr19_+_35030438 1.49 ENST00000415950.5
ENST00000262631.11
SCN1B
sodium voltage-gated channel beta subunit 1
chr22_+_40177917 1.44 ENST00000454349.7
ENST00000335727.13
TNRC6B
trinucleotide repeat containing adaptor 6B
chr17_+_4807119 1.41 ENST00000263088.11
ENST00000572940.5
PLD2
phospholipase D2
chr4_-_89307732 1.41 ENST00000609438.2
GPRIN3
GPRIN family member 3
chr19_+_7903843 1.39 ENST00000397981.7
ENST00000397979.4
ENST00000397983.7
MAP2K7
mitogen-activated protein kinase kinase 7
chr9_-_127916978 1.38 ENST00000361444.3
ENST00000335791.10
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr17_-_60526167 1.37 ENST00000083182.8
APPBP2
amyloid beta precursor protein binding protein 2
chr15_+_58771280 1.34 ENST00000559228.6
ENST00000450403.3
MINDY2
MINDY lysine 48 deubiquitinase 2
chr10_+_70404129 1.32 ENST00000373218.5
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr12_+_100267162 1.32 ENST00000548392.5
ENST00000360820.7
SCYL2
SCY1 like pseudokinase 2
chr1_+_113929600 1.24 ENST00000369558.5
ENST00000369561.8
HIPK1
homeodomain interacting protein kinase 1
chr12_-_389249 1.24 ENST00000535014.5
ENST00000543507.1
ENST00000544760.1
ENST00000399788.7
KDM5A
lysine demethylase 5A
chr3_+_94062974 1.24 ENST00000314622.9
NSUN3
NOP2/Sun RNA methyltransferase 3
chr12_-_54280087 1.20 ENST00000209875.9
CBX5
chromobox 5
chr10_+_79068955 1.20 ENST00000334512.10
ZMIZ1
zinc finger MIZ-type containing 1
chr2_-_25252251 1.16 ENST00000380746.8
ENST00000402667.1
DNMT3A
DNA methyltransferase 3 alpha
chr7_-_72336995 1.16 ENST00000329008.9
CALN1
calneuron 1
chr1_+_27392612 1.13 ENST00000374024.4
GPR3
G protein-coupled receptor 3
chr10_-_70283998 1.13 ENST00000277942.7
NPFFR1
neuropeptide FF receptor 1
chr22_-_18024513 1.11 ENST00000441493.7
MICAL3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr5_+_140664896 1.10 ENST00000358337.10
WDR55
WD repeat domain 55
chr2_+_119759875 1.08 ENST00000263708.7
PTPN4
protein tyrosine phosphatase non-receptor type 4
chrX_+_21839599 1.08 ENST00000379484.10
MBTPS2
membrane bound transcription factor peptidase, site 2
chr16_+_58515474 1.07 ENST00000310682.6
ENST00000394266.8
SETD6
SET domain containing 6, protein lysine methyltransferase
chr17_-_45490696 1.05 ENST00000430334.8
ENST00000584420.1
ENST00000589780.5
PLEKHM1
pleckstrin homology and RUN domain containing M1
chr10_+_74826550 1.04 ENST00000649657.1
ENST00000372714.6
ENST00000649442.1
ENST00000648539.1
ENST00000647666.1
ENST00000648048.1
ENST00000287239.10
ENST00000649375.1
KAT6B
lysine acetyltransferase 6B
chr22_+_29073024 1.03 ENST00000400335.9
KREMEN1
kringle containing transmembrane protein 1
chr3_-_142225556 1.03 ENST00000392993.7
GK5
glycerol kinase 5
chr22_-_43187078 0.98 ENST00000216129.7
TTLL12
tubulin tyrosine ligase like 12
chr15_-_78944985 0.98 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
CTSH
cathepsin H
chr11_+_131370478 0.96 ENST00000374791.7
ENST00000683400.1
ENST00000436745.5
NTM
neurotrimin
chr3_-_48662877 0.95 ENST00000164024.5
CELSR3
cadherin EGF LAG seven-pass G-type receptor 3
chr15_+_41774459 0.94 ENST00000457542.7
ENST00000456763.6
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr10_-_118754956 0.94 ENST00000369151.8
CACUL1
CDK2 associated cullin domain 1
chr11_+_33257265 0.91 ENST00000303296.9
ENST00000379016.7
HIPK3
homeodomain interacting protein kinase 3
chr10_-_20897288 0.90 ENST00000377122.9
NEBL
nebulette
chr16_+_67842277 0.90 ENST00000303596.3
THAP11
THAP domain containing 11
chr3_+_138347648 0.90 ENST00000614350.4
ENST00000289104.8
MRAS
muscle RAS oncogene homolog
chr17_-_8152380 0.89 ENST00000317276.9
PER1
period circadian regulator 1
chr13_+_34942263 0.88 ENST00000379939.7
ENST00000400445.7
NBEA
neurobeachin
chr2_+_69915100 0.88 ENST00000264444.7
MXD1
MAX dimerization protein 1
chr13_-_106568107 0.88 ENST00000400198.8
ARGLU1
arginine and glutamate rich 1
chr2_-_11344580 0.87 ENST00000616279.4
ENST00000315872.11
ROCK2
Rho associated coiled-coil containing protein kinase 2
chr16_+_84699969 0.87 ENST00000563892.5
ENST00000219473.12
ENST00000562283.5
ENST00000570191.5
ENST00000569038.5
ENST00000570053.1
USP10
ubiquitin specific peptidase 10
chr20_-_4015389 0.86 ENST00000336095.10
RNF24
ring finger protein 24
chr9_-_125143457 0.86 ENST00000373549.8
ENST00000336505.11
SCAI
suppressor of cancer cell invasion
chr2_+_230864921 0.84 ENST00000326427.11
ENST00000335005.10
ENST00000326407.10
ITM2C
integral membrane protein 2C
chr12_+_69470349 0.83 ENST00000547219.5
ENST00000550316.5
ENST00000548154.5
ENST00000547414.5
ENST00000549921.6
ENST00000550389.5
ENST00000550937.5
ENST00000549092.5
ENST00000550169.5
FRS2
fibroblast growth factor receptor substrate 2
chr11_-_78341876 0.82 ENST00000340149.6
GAB2
GRB2 associated binding protein 2
chr12_-_30695852 0.79 ENST00000256079.9
IPO8
importin 8
chr2_-_212538766 0.78 ENST00000342788.9
ERBB4
erb-b2 receptor tyrosine kinase 4
chrX_+_70444855 0.78 ENST00000194900.8
DLG3
discs large MAGUK scaffold protein 3
chr1_-_31239880 0.77 ENST00000373736.7
NKAIN1
sodium/potassium transporting ATPase interacting 1
chr20_-_5001474 0.76 ENST00000338244.6
SLC23A2
solute carrier family 23 member 2
chr10_+_135067 0.76 ENST00000381591.5
ZMYND11
zinc finger MYND-type containing 11
chr3_+_50236192 0.75 ENST00000313601.11
GNAI2
G protein subunit alpha i2
chr19_+_56141317 0.73 ENST00000592949.5
ZNF444
zinc finger protein 444
chr1_-_201023694 0.73 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
KIF21B
kinesin family member 21B
chr12_+_122078740 0.69 ENST00000319080.12
MLXIP
MLX interacting protein
chr4_-_185956348 0.69 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
SORBS2
sorbin and SH3 domain containing 2
chr5_-_95284535 0.68 ENST00000515393.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr17_+_56834081 0.68 ENST00000572810.1
ENST00000284061.8
DGKE
diacylglycerol kinase epsilon
chr8_+_105318428 0.67 ENST00000407775.7
ZFPM2
zinc finger protein, FOG family member 2
chr11_+_68460712 0.67 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
PPP6R3
protein phosphatase 6 regulatory subunit 3
chr9_+_112486819 0.67 ENST00000337530.11
KIAA1958
KIAA1958
chr4_+_705748 0.67 ENST00000419774.5
ENST00000362003.9
ENST00000400151.6
ENST00000427463.5
ENST00000470161.6
PCGF3
polycomb group ring finger 3
chr11_-_65614195 0.66 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr6_-_110815408 0.66 ENST00000368911.8
CDK19
cyclin dependent kinase 19
chr11_-_68213277 0.64 ENST00000401547.6
ENST00000304363.9
ENST00000453170.5
KMT5B
lysine methyltransferase 5B
chr3_+_98732236 0.64 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr1_+_180632001 0.63 ENST00000367590.9
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr5_-_74640719 0.63 ENST00000302351.9
ENST00000509127.2
ENC1
ectodermal-neural cortex 1
chr12_-_120369156 0.62 ENST00000257552.7
MSI1
musashi RNA binding protein 1
chr16_-_70439045 0.61 ENST00000342907.3
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr9_+_126914760 0.61 ENST00000424082.6
ENST00000259351.10
ENST00000394022.7
ENST00000394011.7
ENST00000319107.8
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr11_-_119095456 0.60 ENST00000530167.1
H2AX
H2A.X variant histone
chr17_+_40318237 0.60 ENST00000394089.6
ENST00000425707.7
RARA
retinoic acid receptor alpha
chr11_-_115504389 0.59 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr9_-_37034261 0.58 ENST00000358127.9
ENST00000377852.7
ENST00000523241.6
PAX5
paired box 5
chr14_-_99604167 0.57 ENST00000380243.9
CCDC85C
coiled-coil domain containing 85C
chr2_+_10043524 0.57 ENST00000305883.6
KLF11
Kruppel like factor 11
chr8_-_20303955 0.55 ENST00000381569.5
LZTS1
leucine zipper tumor suppressor 1
chr3_-_56801939 0.55 ENST00000296315.8
ENST00000495373.5
ARHGEF3
Rho guanine nucleotide exchange factor 3
chr17_+_2337480 0.54 ENST00000268989.8
ENST00000426855.6
SGSM2
small G protein signaling modulator 2
chr16_+_77191173 0.53 ENST00000248248.8
ENST00000439557.6
ENST00000545553.1
MON1B
MON1 homolog B, secretory trafficking associated
chr1_+_76867469 0.51 ENST00000477717.6
ST6GALNAC5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr12_-_116881431 0.49 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein
chr7_-_148884159 0.48 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr15_+_51751587 0.48 ENST00000539962.6
ENST00000249700.9
TMOD2
tropomodulin 2
chrX_+_118974608 0.48 ENST00000304778.11
ENST00000371628.8
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr16_+_68311126 0.47 ENST00000339507.9
PRMT7
protein arginine methyltransferase 7
chr9_-_36400260 0.46 ENST00000259605.11
ENST00000353739.8
ENST00000611646.4
RNF38
ring finger protein 38
chr5_+_122312229 0.45 ENST00000261368.13
SNCAIP
synuclein alpha interacting protein
chr17_-_41734641 0.44 ENST00000347901.9
ENST00000393939.6
ENST00000341193.9
ENST00000310778.5
HAP1
huntingtin associated protein 1
chr2_+_74529923 0.44 ENST00000258080.8
ENST00000352222.7
HTRA2
HtrA serine peptidase 2
chr10_+_67884646 0.44 ENST00000212015.11
SIRT1
sirtuin 1
chr18_-_59359245 0.43 ENST00000251047.6
LMAN1
lectin, mannose binding 1
chr13_+_110713640 0.41 ENST00000333219.9
ING1
inhibitor of growth family member 1
chr14_-_26597430 0.40 ENST00000344429.9
ENST00000574031.1
ENST00000465357.6
ENST00000547619.5
NOVA1
NOVA alternative splicing regulator 1
chr17_+_7705193 0.40 ENST00000226091.3
EFNB3
ephrin B3
chr1_-_1390943 0.39 ENST00000408952.8
CCNL2
cyclin L2
chr9_+_97853217 0.39 ENST00000375123.5
FOXE1
forkhead box E1
chr5_+_149730260 0.38 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARGC1B
PPARG coactivator 1 beta
chr10_+_96832252 0.38 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
LCOR
ligand dependent nuclear receptor corepressor
chr14_+_66508127 0.38 ENST00000459628.5
ENST00000478722.6
GPHN
gephyrin
chr20_+_43457885 0.38 ENST00000668808.1
ENST00000670741.1
ENST00000662078.1
ENST00000244020.5
ENST00000657241.1
SRSF6
ENSG00000288000.1
serine and arginine rich splicing factor 6
novel protein
chr15_-_74695987 0.37 ENST00000563009.5
ENST00000568176.5
ENST00000566243.5
ENST00000566219.1
ENST00000426797.7
ENST00000315127.9
ENST00000566119.5
EDC3
enhancer of mRNA decapping 3
chr4_+_86934976 0.36 ENST00000507468.5
ENST00000395146.9
AFF1
AF4/FMR2 family member 1
chr7_-_73522278 0.36 ENST00000404251.1
ENST00000339594.9
BAZ1B
bromodomain adjacent to zinc finger domain 1B
chr19_+_13024573 0.34 ENST00000358552.7
ENST00000360105.8
ENST00000588228.5
ENST00000676441.1
ENST00000591028.1
NFIX
nuclear factor I X
chr15_+_64841873 0.33 ENST00000616065.4
ENST00000323544.5
PLEKHO2
pleckstrin homology domain containing O2
chr19_+_29811944 0.33 ENST00000262643.8
ENST00000575243.5
CCNE1
cyclin E1
chr1_+_9234748 0.32 ENST00000377403.7
H6PD
hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
chr15_-_75451650 0.31 ENST00000567289.5
ENST00000394947.8
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr15_-_68229658 0.31 ENST00000565471.6
ENST00000637494.1
ENST00000636314.1
ENST00000637667.1
ENST00000564752.1
ENST00000566347.5
ENST00000249806.11
ENST00000562767.2
CLN6
ENSG00000260007.3
CLN6 transmembrane ER protein
novel protein
chr17_-_6556447 0.31 ENST00000421306.7
PITPNM3
PITPNM family member 3
chr11_+_63839086 0.31 ENST00000350490.11
ENST00000402010.8
MARK2
microtubule affinity regulating kinase 2
chr1_+_32539418 0.30 ENST00000373510.9
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr2_+_26692686 0.30 ENST00000620977.1
ENST00000302909.4
KCNK3
potassium two pore domain channel subfamily K member 3
chr7_-_99408548 0.29 ENST00000626285.1
ENST00000350498.8
PDAP1
PDGFA associated protein 1
chr16_-_85688912 0.29 ENST00000253462.8
GINS2
GINS complex subunit 2
chr7_+_31052297 0.29 ENST00000304166.9
ADCYAP1R1
ADCYAP receptor type I
chr1_+_19882374 0.29 ENST00000375120.4
OTUD3
OTU deubiquitinase 3
chr1_+_36224410 0.28 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
THRAP3
thyroid hormone receptor associated protein 3
chr19_-_1652576 0.28 ENST00000453954.6
ENST00000395423.7
ENST00000262965.12
ENST00000588136.7
TCF3
transcription factor 3
chr11_-_70661762 0.28 ENST00000357171.7
ENST00000412252.5
ENST00000449833.6
ENST00000338508.8
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr18_+_48539017 0.26 ENST00000256413.8
CTIF
cap binding complex dependent translation initiation factor
chr2_-_231926328 0.25 ENST00000295440.2
ENST00000409852.2
NPPC
natriuretic peptide C
chr15_-_89912882 0.25 ENST00000398333.7
ENST00000357484.10
ARPIN-AP3S2
ARPIN
ARPIN-AP3S2 readthrough
actin related protein 2/3 complex inhibitor
chr6_+_35342535 0.25 ENST00000360694.8
ENST00000418635.6
ENST00000448077.6
PPARD
peroxisome proliferator activated receptor delta
chr1_-_37554277 0.25 ENST00000296215.8
SNIP1
Smad nuclear interacting protein 1
chr8_-_42051978 0.25 ENST00000265713.8
ENST00000648335.1
ENST00000485568.5
ENST00000426524.6
ENST00000396930.4
ENST00000406337.6
KAT6A
lysine acetyltransferase 6A
chr14_+_69398683 0.24 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
SLC39A9
solute carrier family 39 member 9
chr2_+_172556039 0.24 ENST00000410055.5
ENST00000282077.8
PDK1
pyruvate dehydrogenase kinase 1
chr6_-_31660735 0.23 ENST00000375911.2
C6orf47
chromosome 6 open reading frame 47
chr9_-_123930107 0.22 ENST00000373624.6
ENST00000373620.7
ENST00000373618.1
DENND1A
DENN domain containing 1A
chr2_+_24491860 0.21 ENST00000406961.5
ENST00000405141.5
NCOA1
nuclear receptor coactivator 1
chr7_+_4682252 0.21 ENST00000328914.5
FOXK1
forkhead box K1
chr19_-_663174 0.21 ENST00000292363.10
ENST00000589762.5
RNF126
ring finger protein 126

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
2.2 6.5 GO:0042137 sequestering of neurotransmitter(GO:0042137)
1.4 4.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.5 5.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.5 1.9 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.4 3.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4 1.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.4 1.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.4 3.9 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 2.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.3 4.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 1.0 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 0.9 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.3 1.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.3 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 2.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 1.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 0.8 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 1.5 GO:0021966 corticospinal neuron axon guidance(GO:0021966) Purkinje myocyte action potential(GO:0086017) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 0.7 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 1.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 0.9 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.2 0.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.9 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 1.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.2 1.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 2.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 3.2 GO:1990403 embryonic brain development(GO:1990403)
0.2 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.2 2.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.2 5.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.2 0.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.9 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 2.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.2 1.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 4.6 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.2 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.2 2.0 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 0.5 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 1.8 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 1.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.4 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 1.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 6.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:0019086 late viral transcription(GO:0019086)
0.1 0.4 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.3 GO:0033058 directional locomotion(GO:0033058)
0.1 2.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 6.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 7.1 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 1.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 1.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.1 3.1 GO:0097503 sialylation(GO:0097503)
0.1 0.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 1.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.6 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 3.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.8 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 3.8 GO:0090102 cochlea development(GO:0090102)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 1.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.2 GO:0003358 noradrenergic neuron development(GO:0003358) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 1.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.6 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.4 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.8 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 2.2 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 1.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.3 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.0 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0071878 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) negative regulation of adrenergic receptor signaling pathway(GO:0071878)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.3 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 1.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617) positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 1.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.6 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.4 GO:0007628 adult walking behavior(GO:0007628)
0.0 1.1 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.9 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 2.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 2.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.1 6.5 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.0 3.1 GO:0034657 GID complex(GO:0034657)
0.7 2.2 GO:0044609 DBIRD complex(GO:0044609)
0.4 1.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 1.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 4.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 2.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 4.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 3.9 GO:0043218 compact myelin(GO:0043218)
0.1 1.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 5.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.4 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0001741 XY body(GO:0001741)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 3.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 4.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 2.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 7.3 GO:0016234 inclusion body(GO:0016234)
0.1 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 2.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 13.6 GO:0030425 dendrite(GO:0030425)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 1.0 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 10.8 GO:0005730 nucleolus(GO:0005730)
0.0 1.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0036126 sperm flagellum(GO:0036126)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
1.1 4.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
1.1 5.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.9 3.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.8 2.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.7 5.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 1.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 4.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5 1.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.5 1.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 6.7 GO:1903136 cuprous ion binding(GO:1903136)
0.4 2.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 2.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4 1.6 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.4 4.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 3.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 10.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 2.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 3.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 1.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.3 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.2 2.0 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.6 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 1.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 5.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 3.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 1.8 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 2.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 2.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 5.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.7 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 2.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 1.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 7.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 3.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0031692 alpha-1B adrenergic receptor binding(GO:0031692)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 5.9 GO:0044325 ion channel binding(GO:0044325)
0.0 1.7 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 11.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 3.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.5 PID ARF6 PATHWAY Arf6 signaling events
0.1 6.3 PID REELIN PATHWAY Reelin signaling pathway
0.1 5.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 7.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 4.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 17.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 4.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 6.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 2.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.8 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 2.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events