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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GFI1B

Z-value: 3.52

Motif logo

Transcription factors associated with GFI1B

Gene Symbol Gene ID Gene Info
ENSG00000165702.15 GFI1B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1Bhg38_v1_chr9_+_132978687_132978772-0.452.4e-12Click!

Activity profile of GFI1B motif

Sorted Z-values of GFI1B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_36608146 10.58 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr6_-_56843638 10.20 ENST00000421834.6
ENST00000370788.6
dystonin
chrX_+_120604199 9.88 ENST00000371315.3
MCTS1 re-initiation and release factor
chr4_-_175812746 9.55 ENST00000393658.6
glycoprotein M6A
chr12_+_48119787 9.40 ENST00000551804.5
phosphofructokinase, muscle
chr12_+_48119323 9.11 ENST00000551339.6
ENST00000629846.2
ENST00000359794.11
ENST00000548345.5
phosphofructokinase, muscle
chr4_+_41360759 7.60 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chrX_+_120604084 7.22 ENST00000371317.10
MCTS1 re-initiation and release factor
chr17_-_81869934 7.20 ENST00000580685.5
Rho GDP dissociation inhibitor alpha
chr17_+_36492202 7.06 ENST00000612494.4
ENST00000622013.1
zinc finger HIT-type containing 3
chr22_+_23862188 7.05 ENST00000433835.3
novel protein
chr17_+_51153551 7.04 ENST00000393196.8
ENST00000336097.7
ENST00000480143.5
ENST00000511355.5
ENST00000393193.6
ENST00000376392.10
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
chr5_-_147081428 7.02 ENST00000394413.7
protein phosphatase 2 regulatory subunit Bbeta
chr12_-_123268077 6.55 ENST00000542174.5
cyclin dependent kinase 2 associated protein 1
chr5_-_126595237 6.55 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr6_-_56843153 6.36 ENST00000361203.7
ENST00000523817.1
dystonin
chr6_-_131000722 6.35 ENST00000528282.5
erythrocyte membrane protein band 4.1 like 2
chr9_-_14180779 6.27 ENST00000380924.1
ENST00000543693.5
nuclear factor I B
chr5_-_147081462 6.23 ENST00000508267.5
ENST00000504198.5
protein phosphatase 2 regulatory subunit Bbeta
chrX_+_78104229 6.21 ENST00000373316.5
phosphoglycerate kinase 1
chr4_+_112861053 6.13 ENST00000672221.1
ankyrin 2
chr14_-_103057509 6.01 ENST00000361246.7
CDC42 binding protein kinase beta
chr1_-_32817311 5.90 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr7_+_80135694 5.84 ENST00000457358.7
G protein subunit alpha i1
chr2_-_10837977 5.81 ENST00000404824.2
protein disulfide isomerase family A member 6
chr19_+_32581178 5.78 ENST00000590247.7
ENST00000419343.7
ENST00000592786.5
ENST00000379316.3
programmed cell death 5
chr6_-_131063207 5.78 ENST00000530481.5
erythrocyte membrane protein band 4.1 like 2
chr6_-_131063233 5.77 ENST00000392427.7
ENST00000337057.8
ENST00000525271.5
ENST00000527411.5
erythrocyte membrane protein band 4.1 like 2
chr19_+_32581410 5.75 ENST00000586035.1
programmed cell death 5
chr7_+_112423137 5.74 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr3_+_172750682 5.70 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr7_-_94655993 5.69 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
sarcoglycan epsilon
chr2_-_55269207 5.66 ENST00000263629.9
ENST00000403721.5
mitochondrial translational initiation factor 2
chr15_+_32641665 5.66 ENST00000300175.8
ENST00000413748.6
ENST00000494364.5
ENST00000497208.5
secretogranin V
chr7_-_94656197 5.63 ENST00000643903.1
ENST00000644122.1
ENST00000447873.6
ENST00000644816.1
ENST00000644375.1
sarcoglycan epsilon
chr16_+_7510102 5.44 ENST00000682918.1
ENST00000683326.1
ENST00000570626.2
RNA binding fox-1 homolog 1
chr2_-_2326378 5.43 ENST00000647618.1
myelin transcription factor 1 like
chr7_+_134891566 5.40 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr6_-_131063272 5.36 ENST00000445890.6
ENST00000368128.6
ENST00000628542.2
erythrocyte membrane protein band 4.1 like 2
chr2_-_2326210 5.36 ENST00000647755.1
myelin transcription factor 1 like
chr6_+_158017048 5.34 ENST00000638626.1
synaptojanin 2
chr7_+_39623547 5.33 ENST00000005257.7
RAS like proto-oncogene A
chr7_-_94656160 5.27 ENST00000644609.1
ENST00000643272.1
ENST00000646137.1
ENST00000646098.1
ENST00000643193.1
ENST00000437425.7
ENST00000644551.1
ENST00000415788.3
sarcoglycan epsilon
chr14_-_52950992 5.23 ENST00000343279.8
ENST00000399304.7
ENST00000395631.6
ENST00000341590.8
fermitin family member 2
chr1_+_204870831 5.22 ENST00000404076.5
ENST00000539706.6
neurofascin
chr4_+_153204410 5.16 ENST00000675838.1
ENST00000674967.1
ENST00000632856.2
ENST00000441616.6
ENST00000433687.2
ENST00000494872.6
ENST00000460908.2
ENST00000675780.1
ENST00000674976.1
ENST00000338700.10
ENST00000675293.1
ENST00000676172.1
ENST00000675673.1
ENST00000675492.1
ENST00000675425.1
ENST00000675384.1
ENST00000675063.1
ENST00000675340.1
ENST00000675835.1
ENST00000675054.1
ENST00000675710.1
ENST00000502281.3
novel protein
tripartite motif containing 2
chr7_+_141738343 5.15 ENST00000498107.5
ENST00000265304.11
ENST00000467681.5
ENST00000465582.5
ENST00000463093.5
single stranded DNA binding protein 1
chr1_+_220094086 5.15 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr14_-_67695747 5.11 ENST00000553384.5
ENST00000381346.9
ENST00000557726.1
retinol dehydrogenase 11
chr2_+_200889327 5.06 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr2_-_9423340 4.98 ENST00000484735.5
ENST00000456913.6
integrin subunit beta 1 binding protein 1
chr7_+_141738321 4.96 ENST00000612337.4
single stranded DNA binding protein 1
chr7_+_73692596 4.86 ENST00000453316.1
BUD23 rRNA methyltransferase and ribosome maturation factor
chr3_-_165837412 4.85 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr17_-_81937221 4.82 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
pyrroline-5-carboxylate reductase 1
chr10_+_31321152 4.78 ENST00000446923.7
zinc finger E-box binding homeobox 1
chr18_+_58864866 4.76 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr4_+_41935114 4.72 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
transmembrane protein 33
chr2_+_200889411 4.68 ENST00000409357.5
ENST00000409129.2
NGG1 interacting factor 3 like 1
chr2_-_9423190 4.64 ENST00000497105.1
ENST00000360635.7
ENST00000359712.7
integrin subunit beta 1 binding protein 1
chr1_+_164559173 4.60 ENST00000420696.7
PBX homeobox 1
chr17_+_72121012 4.58 ENST00000245479.3
SRY-box transcription factor 9
chr8_-_48921419 4.55 ENST00000020945.4
snail family transcriptional repressor 2
chr7_+_56051756 4.55 ENST00000275603.9
chaperonin containing TCP1 subunit 6A
chr17_-_48610971 4.52 ENST00000239165.9
homeobox B7
chr10_+_61901678 4.39 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr11_-_61815106 4.36 ENST00000539419.5
ENST00000545245.5
ENST00000545405.5
ENST00000542506.5
fatty acid desaturase 1
chr17_-_81937277 4.36 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
pyrroline-5-carboxylate reductase 1
chr7_+_134891400 4.26 ENST00000393118.6
caldesmon 1
chr11_+_26188836 4.24 ENST00000672621.1
anoctamin 3
chr6_+_44247866 4.20 ENST00000371554.2
heat shock protein 90 alpha family class B member 1
chr1_-_148483302 4.17 ENST00000419275.3
peptidylprolyl isomerase A like 4G
chr5_-_142698004 4.15 ENST00000407758.5
ENST00000441680.6
ENST00000419524.6
ENST00000621536.4
fibroblast growth factor 1
chr12_+_95474081 4.12 ENST00000546753.5
methionyl aminopeptidase 2
chr17_-_10026265 4.11 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr3_-_33718207 4.01 ENST00000359576.9
ENST00000682230.1
ENST00000399362.8
cytoplasmic linker associated protein 2
chr17_-_31297231 4.01 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr9_-_14321948 3.94 ENST00000635877.1
ENST00000636432.1
ENST00000646622.1
nuclear factor I B
chr5_+_14143322 3.94 ENST00000344204.9
trio Rho guanine nucleotide exchange factor
chr17_-_81937320 3.94 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
pyrroline-5-carboxylate reductase 1
chr5_+_160009113 3.78 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
tetratricopeptide repeat domain 1
chr19_-_43619591 3.60 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr2_-_9423444 3.53 ENST00000488451.5
ENST00000238091.8
ENST00000355346.9
integrin subunit beta 1 binding protein 1
chr22_-_27919199 3.47 ENST00000634017.1
ENST00000436663.1
ENST00000320996.14
ENST00000335272.10
ENST00000455418.7
phosphatidylinositol transfer protein beta
chr5_+_80407994 3.47 ENST00000338008.9
ENST00000510158.5
zinc finger FYVE-type containing 16
chr5_+_80408031 3.44 ENST00000505560.5
ENST00000509562.2
zinc finger FYVE-type containing 16
chr4_+_153222307 3.41 ENST00000675899.1
ENST00000675611.1
ENST00000674872.1
ENST00000676167.1
tripartite motif containing 2
chr17_-_81514629 3.40 ENST00000681052.1
ENST00000575659.6
actin gamma 1
chr4_+_153222402 3.38 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr10_-_128126204 3.33 ENST00000368653.7
marker of proliferation Ki-67
chr5_-_126595185 3.31 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
aldehyde dehydrogenase 7 family member A1
chr7_-_108456321 3.29 ENST00000379024.8
ENST00000351718.8
neuronal cell adhesion molecule
chr20_+_49219398 3.25 ENST00000618172.5
DEAD-box helicase 27
chr1_+_149583865 3.24 ENST00000585245.2
peptidylprolyl isomerase A like 4C
chr20_+_36091409 3.23 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1
chr9_+_12693327 3.21 ENST00000388918.10
tyrosinase related protein 1
chr1_+_95151377 3.20 ENST00000604203.1
TLCD4-RWDD3 readthrough
chr7_-_108456378 3.18 ENST00000613830.4
ENST00000413765.6
ENST00000379028.8
neuronal cell adhesion molecule
chr2_-_157874976 3.12 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
activin A receptor type 1
chr12_+_116738285 3.12 ENST00000392549.7
ENST00000407967.7
ring finger protein, transmembrane 2
chr6_+_143450797 3.11 ENST00000367591.5
ENST00000367592.5
peroxisomal biogenesis factor 3
chr11_+_94128834 3.08 ENST00000227638.8
ENST00000436171.2
pannexin 1
chr11_-_95923763 3.05 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
myotubularin related protein 2
chr11_+_35662739 3.02 ENST00000299413.7
tripartite motif containing 44
chr5_+_151212117 2.99 ENST00000523466.5
GM2 ganglioside activator
chr2_+_54456311 2.98 ENST00000615901.4
ENST00000356805.9
spectrin beta, non-erythrocytic 1
chr1_-_93585071 2.97 ENST00000539242.5
BCAR3 adaptor protein, NSP family member
chr14_+_61762405 2.91 ENST00000216294.5
small nuclear RNA activating complex polypeptide 1
chr19_-_55149193 2.86 ENST00000587758.5
ENST00000588981.6
ENST00000356783.9
ENST00000291901.12
ENST00000588426.5
ENST00000536926.5
ENST00000588147.5
troponin T1, slow skeletal type
chr14_+_78403686 2.85 ENST00000553631.1
ENST00000554719.5
neurexin 3
chr1_+_162632454 2.81 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr12_+_6494087 2.81 ENST00000382457.8
ENST00000315579.10
non-SMC condensin I complex subunit D2
chr11_-_61891534 2.80 ENST00000278829.7
fatty acid desaturase 3
chr1_-_144373659 2.80 ENST00000581164.1
peptidylprolyl isomerase A like 4E
chr11_-_33753394 2.78 ENST00000532057.5
ENST00000531080.5
F-box protein 3
chr10_-_128126405 2.74 ENST00000368654.8
marker of proliferation Ki-67
chr19_+_21082224 2.71 ENST00000620627.1
zinc finger protein 714
chr11_-_117877463 2.66 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr2_-_157875820 2.65 ENST00000672582.1
ENST00000673324.1
ENST00000539637.6
ENST00000413751.1
ENST00000424669.6
ENST00000684348.1
activin A receptor type 1
chr2_+_11612253 2.60 ENST00000396123.2
growth regulating estrogen receptor binding 1
chr7_+_39623886 2.60 ENST00000436179.1
RAS like proto-oncogene A
chr2_-_96208815 2.59 ENST00000443962.1
ENST00000337288.10
StAR related lipid transfer domain containing 7
chr1_-_145242124 2.54 ENST00000544708.2
peptidylprolyl isomerase A like 4D
chr16_+_4476340 2.54 ENST00000458134.7
ENST00000619528.4
ENST00000619913.4
ENST00000219700.10
ENST00000570646.6
ENST00000575120.5
ENST00000572812.5
ENST00000574466.5
ENST00000576827.5
ENST00000570445.5
heme oxygenase 2
chr20_-_33674359 2.52 ENST00000606690.5
ENST00000439478.5
ENST00000246190.11
ENST00000375238.8
N-terminal EF-hand calcium binding protein 3
chr1_+_144592868 2.50 ENST00000581138.3
peptidylprolyl isomerase A like 4F
chr7_-_101165114 2.42 ENST00000445482.2
VGF nerve growth factor inducible
chr1_+_120889746 2.36 ENST00000577856.2
peptidylprolyl isomerase A like 4A
chrX_+_7219431 2.30 ENST00000674499.1
ENST00000217961.5
steroid sulfatase
chr12_+_116738308 2.25 ENST00000257575.9
ring finger protein, transmembrane 2
chr22_+_38468036 2.23 ENST00000409006.3
ENST00000216014.9
KDEL endoplasmic reticulum protein retention receptor 3
chr15_-_34039042 2.22 ENST00000306730.8
apoptosis and caspase activation inhibitor
chr1_-_21050952 2.21 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr14_+_28766755 2.21 ENST00000313071.7
forkhead box G1
chr17_-_39607876 2.10 ENST00000302584.5
neuronal differentiation 2
chr22_+_19479826 2.04 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr11_-_102724781 2.00 ENST00000438475.2
matrix metallopeptidase 8
chr5_+_15500172 1.98 ENST00000504595.2
F-box and leucine rich repeat protein 7
chr1_+_226548747 1.97 ENST00000366788.8
ENST00000366789.5
stum, mechanosensory transduction mediator homolog
chr15_+_67166019 1.93 ENST00000537194.6
SMAD family member 3
chr7_-_87219709 1.91 ENST00000257637.8
transmembrane protein 243
chr7_+_148339452 1.91 ENST00000463592.3
contactin associated protein 2
chr18_-_26865732 1.90 ENST00000672188.1
aquaporin 4
chr3_+_173398438 1.87 ENST00000457714.5
neuroligin 1
chr11_-_102724945 1.82 ENST00000236826.8
matrix metallopeptidase 8
chr6_+_36676455 1.79 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr1_-_220046432 1.76 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr2_-_85888897 1.75 ENST00000639305.1
ENST00000638986.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_201129318 1.71 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr3_+_37020333 1.68 ENST00000616768.5
mutL homolog 1
chr1_+_26021768 1.67 ENST00000374280.4
exostosin like glycosyltransferase 1
chr18_-_51197671 1.66 ENST00000406189.4
mex-3 RNA binding family member C
chr14_-_63728027 1.66 ENST00000247225.7
sphingosine-1-phosphate phosphatase 1
chr2_-_157876301 1.66 ENST00000434821.7
activin A receptor type 1
chr2_-_85888958 1.62 ENST00000377332.8
ENST00000639119.1
ENST00000638572.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr17_-_9959455 1.61 ENST00000580865.5
ENST00000583882.5
growth arrest specific 7
chr10_+_70815889 1.61 ENST00000373202.8
sphingosine-1-phosphate lyase 1
chr1_-_114757971 1.61 ENST00000261443.9
ENST00000534699.5
ENST00000339438.10
ENST00000358528.9
ENST00000529046.5
ENST00000525970.5
ENST00000369530.5
ENST00000530886.5
ENST00000610726.4
cold shock domain containing E1
chr2_-_85561513 1.61 ENST00000430215.7
gamma-glutamyl carboxylase
chr6_-_116279837 1.58 ENST00000368608.4
TSPY like 1
chr15_+_90388234 1.57 ENST00000268182.10
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chr19_+_17751467 1.55 ENST00000596536.5
ENST00000593870.5
ENST00000598086.5
ENST00000598932.5
ENST00000595023.5
ENST00000594068.5
ENST00000596507.5
ENST00000595033.5
ENST00000597718.5
FCH and mu domain containing endocytic adaptor 1
chr2_-_85888685 1.54 ENST00000638178.1
ENST00000640982.1
ENST00000640992.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr4_-_158159657 1.52 ENST00000590648.5
golgi associated kinase 1B
chr16_-_18375069 1.46 ENST00000545114.5
nuclear pore complex interacting protein family, member A9
chr11_-_26722051 1.46 ENST00000396005.8
solute carrier family 5 member 12
chr3_-_195892706 1.45 ENST00000673038.1
ENST00000678220.1
ENST00000428187.7
tyrosine kinase non receptor 2
chr18_+_11857440 1.45 ENST00000602628.1
G protein subunit alpha L
chr9_-_124500986 1.45 ENST00000373587.3
nuclear receptor subfamily 5 group A member 1
chr7_+_134866831 1.43 ENST00000435928.1
caldesmon 1
chrX_-_72714181 1.42 ENST00000339490.7
ENST00000541944.5
ENST00000373539.3
phosphorylase kinase regulatory subunit alpha 1
chr11_+_123590939 1.42 ENST00000646146.1
GRAM domain containing 1B
chr7_-_101165558 1.41 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr2_-_130129222 1.41 ENST00000409914.7
POTE ankyrin domain family member F
chr7_+_66628864 1.41 ENST00000639828.2
ENST00000275532.8
ENST00000640385.1
potassium channel tetramerization domain containing 7
chr1_+_54715837 1.39 ENST00000371281.4
tetratricopeptide repeat domain 4
chr7_+_98617275 1.39 ENST00000265634.4
neuronal pentraxin 2
chr10_+_86756580 1.38 ENST00000372037.8
bone morphogenetic protein receptor type 1A
chr1_-_146344790 1.37 ENST00000584068.3
peptidylprolyl isomerase A like 4H
chr15_-_58749569 1.37 ENST00000402627.5
ENST00000559053.1
ENST00000260408.8
ENST00000561288.1
ENST00000461408.2
ENST00000439637.5
ENST00000558004.1
ADAM metallopeptidase domain 10
chr12_+_54053815 1.34 ENST00000430889.3
homeobox C4
chr7_+_120951116 1.33 ENST00000431467.1
inhibitor of growth family member 3
chr1_+_35079374 1.32 ENST00000359858.9
ENST00000373330.1
zinc finger MYM-type containing 1
chr9_+_35490103 1.27 ENST00000361226.8
RUN and SH3 domain containing 2
chr20_-_36646146 1.26 ENST00000262866.9
Src like adaptor 2
chr3_-_94062881 1.24 ENST00000619045.1
dihydrofolate reductase 2
chr15_+_70936487 1.22 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr12_+_95474143 1.22 ENST00000261220.13
ENST00000549502.5
ENST00000553151.5
ENST00000323666.10
ENST00000550777.5
ENST00000551840.5
methionyl aminopeptidase 2
chr1_+_150364621 1.21 ENST00000401000.8
regulation of nuclear pre-mRNA domain containing 2
chr11_+_61950063 1.19 ENST00000534553.5
bestrophin 1
chr5_+_140882116 1.18 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr19_+_35745590 1.17 ENST00000591949.1
presenilin enhancer, gamma-secretase subunit
chr16_-_30585497 1.17 ENST00000567773.1
ENST00000395216.3
ENST00000470110.2
zinc finger protein 785
chr16_-_28482634 1.13 ENST00000637378.1
novel protein
chr6_+_12290353 1.12 ENST00000379375.6
endothelin 1
chr14_+_71586261 1.12 ENST00000358550.6
signal induced proliferation associated 1 like 1
chr3_-_94062906 1.12 ENST00000314636.3
ENST00000394221.3
dihydrofolate reductase 2
chr20_-_59032292 1.11 ENST00000395663.1
ENST00000243997.8
ENST00000395659.1
ATP synthase F1 subunit epsilon
chr3_+_50246888 1.09 ENST00000451956.1
G protein subunit alpha i2
chr17_+_77453993 1.09 ENST00000592951.5
septin 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.1 GO:0002188 translation reinitiation(GO:0002188)
3.8 11.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
3.7 18.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
3.5 17.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
3.3 9.9 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
2.5 7.4 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
1.9 5.7 GO:0007518 myoblast fate determination(GO:0007518)
1.6 4.9 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
1.6 4.8 GO:0014016 neuroblast differentiation(GO:0014016)
1.6 12.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.5 4.6 GO:0060018 astrocyte fate commitment(GO:0060018) retinal rod cell differentiation(GO:0060221)
1.5 29.1 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.4 4.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.4 4.2 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
1.4 16.6 GO:0008090 retrograde axonal transport(GO:0008090)
1.2 4.7 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.2 11.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.1 10.6 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.0 3.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.9 10.2 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 3.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.7 10.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.7 4.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.7 2.0 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.7 7.9 GO:0051665 membrane raft localization(GO:0051665)
0.7 3.9 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.6 1.9 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.6 6.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 4.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.6 2.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.6 13.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.5 4.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.5 1.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.5 4.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.5 1.4 GO:0007538 primary sex determination(GO:0007538)
0.5 2.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.5 1.9 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.5 2.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.7 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.4 1.7 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.4 5.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.4 3.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 5.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.4 5.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4 1.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 1.1 GO:0030185 nitric oxide transport(GO:0030185) rhythmic synaptic transmission(GO:0060024)
0.4 3.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.4 3.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.3 1.4 GO:0048372 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.3 1.4 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 5.1 GO:0042574 response to light intensity(GO:0009642) retinal metabolic process(GO:0042574)
0.3 1.7 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.3 4.6 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 6.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 2.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 0.9 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.3 3.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.3 15.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 1.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 9.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 2.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.3 9.8 GO:0048665 neuron fate specification(GO:0048665)
0.2 1.2 GO:0006788 heme oxidation(GO:0006788)
0.2 0.7 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.2 0.7 GO:1900081 negative regulation of cardiac muscle adaptation(GO:0010616) regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 2.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 2.0 GO:0010265 SCF complex assembly(GO:0010265)
0.2 4.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.2 6.2 GO:0031639 plasminogen activation(GO:0031639)
0.2 6.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 1.8 GO:0060574 columnar/cuboidal epithelial cell maturation(GO:0002069) intestinal epithelial cell maturation(GO:0060574)
0.2 4.6 GO:0002021 response to dietary excess(GO:0002021)
0.2 4.5 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2 1.9 GO:1903944 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 7.2 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.2 6.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 0.6 GO:0036269 swimming behavior(GO:0036269)
0.2 1.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 2.5 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.9 GO:0061743 motor learning(GO:0061743)
0.1 1.9 GO:0007220 Notch receptor processing(GO:0007220)
0.1 1.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.6 GO:1904754 positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1 1.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 4.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 4.4 GO:0016577 histone demethylation(GO:0016577)
0.1 6.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 3.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 2.1 GO:0033622 integrin activation(GO:0033622)
0.1 5.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.1 5.8 GO:0001895 retina homeostasis(GO:0001895)
0.1 2.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 5.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 2.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 5.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 3.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 3.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.1 GO:0007213 adenosine receptor signaling pathway(GO:0001973) G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.2 GO:0035900 response to isolation stress(GO:0035900)
0.1 3.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 4.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 4.0 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 3.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.9 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.7 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 1.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.8 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 1.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.9 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 21.5 GO:0003012 muscle system process(GO:0003012)
0.0 1.0 GO:0006706 steroid catabolic process(GO:0006706)
0.0 9.0 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 1.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 3.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.4 GO:0008306 associative learning(GO:0008306)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 2.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0007140 male meiosis(GO:0007140)
0.0 0.8 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0044241 lipid digestion(GO:0044241)
0.0 0.7 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0006308 DNA catabolic process(GO:0006308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.6 GO:0031673 H zone(GO:0031673)
3.1 18.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
2.1 16.6 GO:0016012 sarcoglycan complex(GO:0016012)
1.9 7.4 GO:0048179 activin receptor complex(GO:0048179)
1.5 26.2 GO:0008091 spectrin(GO:0008091)
1.4 4.2 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
1.1 5.7 GO:0097149 centralspindlin complex(GO:0097149)
1.0 5.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.9 2.8 GO:0000799 nuclear condensin complex(GO:0000799)
0.7 3.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.7 11.1 GO:0030478 actin cap(GO:0030478)
0.7 2.0 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5 10.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 10.6 GO:0044295 axonal growth cone(GO:0044295)
0.4 1.7 GO:0005715 late recombination nodule(GO:0005715)
0.4 4.0 GO:0045180 basal cortex(GO:0045180)
0.4 1.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 1.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 13.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 6.5 GO:0043194 axon initial segment(GO:0043194)
0.3 2.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 4.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 4.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 17.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 2.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 4.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 2.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 3.4 GO:0097433 dense body(GO:0097433)
0.2 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 3.1 GO:0032059 bleb(GO:0032059)
0.2 10.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 3.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 5.8 GO:0099738 cell cortex region(GO:0099738)
0.1 2.9 GO:0005861 troponin complex(GO:0005861)
0.1 1.9 GO:0033010 paranodal junction(GO:0033010)
0.1 1.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 5.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 6.1 GO:0031430 M band(GO:0031430)
0.1 7.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 5.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 6.0 GO:0042641 actomyosin(GO:0042641)
0.1 16.1 GO:0001726 ruffle(GO:0001726)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 3.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 25.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 9.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0097342 ripoptosome(GO:0097342)
0.0 3.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 6.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 5.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 2.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 4.6 GO:0005938 cell cortex(GO:0005938)
0.0 2.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.0 GO:0005903 brush border(GO:0005903)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 4.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 11.5 GO:0005694 chromosome(GO:0005694)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 5.9 GO:0030424 axon(GO:0030424)
0.0 3.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.6 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
2.6 7.9 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
2.3 23.3 GO:0042731 PH domain binding(GO:0042731)
2.3 18.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.2 12.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
2.1 6.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.5 4.4 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
1.4 4.2 GO:0002135 CTP binding(GO:0002135)
1.2 7.4 GO:0016361 activin receptor activity, type I(GO:0016361)
1.2 4.9 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.2 4.8 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
1.1 4.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.0 3.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
1.0 3.0 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.9 7.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9 5.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.8 11.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.8 20.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 4.9 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.8 10.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 13.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.6 5.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 5.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.6 2.4 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.6 2.3 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.5 13.9 GO:0005523 tropomyosin binding(GO:0005523)
0.5 2.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 1.7 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.4 7.0 GO:0019215 intermediate filament binding(GO:0019215)
0.4 4.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 5.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 9.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.4 5.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 1.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 1.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.3 1.0 GO:0004040 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 1.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 5.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 1.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 1.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.3 15.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 4.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 13.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 0.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 2.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 2.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 1.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 15.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 6.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 4.1 GO:0044548 S100 protein binding(GO:0044548)
0.2 7.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 4.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.8 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.7 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 12.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.7 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.7 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 2.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.9 GO:0015250 water channel activity(GO:0015250)
0.1 6.1 GO:0030507 spectrin binding(GO:0030507)
0.1 3.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 4.4 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 6.9 GO:0070888 E-box binding(GO:0070888)
0.1 1.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 11.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 14.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 10.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 9.6 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 2.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 6.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 7.8 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 2.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 3.2 GO:0005507 copper ion binding(GO:0005507)
0.0 1.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 16.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 7.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 3.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.4 PID ALK2 PATHWAY ALK2 signaling events
0.3 8.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 6.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 13.1 PID ATR PATHWAY ATR signaling pathway
0.2 19.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 8.3 PID BMP PATHWAY BMP receptor signaling
0.1 9.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 10.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 16.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 7.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 6.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 4.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.1 PID FGF PATHWAY FGF signaling pathway
0.1 5.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.8 PID AURORA B PATHWAY Aurora B signaling
0.1 4.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 3.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 24.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 8.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.4 7.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 5.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 7.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 2.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3 9.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 5.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 4.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 3.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.2 4.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 7.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 9.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 11.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 20.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 2.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 5.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 8.8 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 4.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 4.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 2.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 10.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 9.4 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex