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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GGAAUGU

Z-value: 6.99

Motif logo

miRNA associated with seed GGAAUGU

NamemiRBASE accession
MIMAT0000416
MIMAT0000462
MIMAT0003281

Activity profile of GGAAUGU motif

Sorted Z-values of GGAAUGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAAUGU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_108731505 43.20 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr1_-_159923717 32.45 ENST00000368096.5
transgelin 2
chr1_+_26280117 29.02 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr6_+_47477731 26.59 ENST00000359314.5
CD2 associated protein
chr1_+_10399054 26.25 ENST00000270776.13
ENST00000483936.5
phosphogluconate dehydrogenase
chr3_-_53256009 25.78 ENST00000296289.10
ENST00000462138.6
ENST00000423516.5
transketolase
chrX_-_154546832 25.75 ENST00000433845.1
ENST00000439227.5
ENST00000393562.10
glucose-6-phosphate dehydrogenase
chr15_-_60397964 25.41 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr8_-_102864155 25.30 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr8_-_100952918 25.14 ENST00000395957.6
ENST00000395948.6
ENST00000457309.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr15_+_65530418 24.78 ENST00000562901.5
ENST00000261875.10
ENST00000442729.6
ENST00000565299.5
ENST00000568793.5
3-hydroxyacyl-CoA dehydratase 3
chr12_+_103930332 24.76 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr3_+_172040554 24.56 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr1_+_112619824 23.59 ENST00000263168.4
capping actin protein of muscle Z-line subunit alpha 1
chr12_+_68610858 23.51 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B, member of RAS oncogene family
chr22_-_38700655 23.01 ENST00000216039.9
Josephin domain containing 1
chr3_-_195442977 22.67 ENST00000326793.11
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr9_+_97983332 22.55 ENST00000339399.5
acidic nuclear phosphoprotein 32 family member B
chr17_+_59619885 21.65 ENST00000269122.8
ENST00000580081.1
ENST00000579456.5
clathrin heavy chain
chr5_+_139293728 21.42 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr3_-_72446623 20.81 ENST00000477973.4
RING1 and YY1 binding protein
chr14_+_51240205 20.21 ENST00000457354.7
thioredoxin related transmembrane protein 1
chr12_-_120469655 20.20 ENST00000229390.8
serine and arginine rich splicing factor 9
chr11_+_118359572 19.85 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr18_+_32091849 19.10 ENST00000261593.8
ENST00000578914.1
ring finger protein 138
chr17_+_59707636 18.97 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr2_+_69742125 18.79 ENST00000394295.6
annexin A4
chr2_-_197499826 18.65 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr14_+_20469399 18.41 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr3_+_128052390 18.33 ENST00000481210.5
ENST00000243253.8
SEC61 translocon subunit alpha 1
chr5_+_122775062 18.16 ENST00000379516.7
ENST00000505934.5
ENST00000514949.1
sorting nexin 2
chr5_+_72816643 17.92 ENST00000337273.10
ENST00000523768.5
transportin 1
chr7_+_99325857 17.91 ENST00000638617.1
ENST00000262942.10
novel protein, ARPC1A and ARPC1B readthrough
actin related protein 2/3 complex subunit 1A
chr1_-_88891496 17.40 ENST00000448623.5
ENST00000370500.10
ENST00000418217.1
general transcription factor IIB
chr18_+_3451647 17.30 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr10_+_102776237 17.14 ENST00000369889.5
WW domain binding protein 1 like
chr3_-_167734832 16.97 ENST00000464360.5
ENST00000492139.5
ENST00000471885.5
ENST00000392750.7
ENST00000470131.5
programmed cell death 10
chr16_-_28211476 16.95 ENST00000569951.1
ENST00000565698.5
exportin 6
chr5_+_87268922 16.91 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RAS p21 protein activator 1
chr12_-_76559504 16.81 ENST00000547544.5
ENST00000393249.6
oxysterol binding protein like 8
chr1_-_150974823 16.62 ENST00000361419.9
ENST00000368954.10
ceramide synthase 2
chr2_-_96208815 16.53 ENST00000443962.1
ENST00000337288.10
StAR related lipid transfer domain containing 7
chr5_+_151771884 16.33 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr17_+_51166398 16.07 ENST00000512737.6
ENST00000503064.5
ENST00000393183.7
NME/NM23 nucleoside diphosphate kinase 2
chr11_-_76381053 16.07 ENST00000260045.8
THAP domain containing 12
chr8_+_58553216 15.75 ENST00000447182.6
ENST00000413219.6
ENST00000424270.6
ENST00000523483.5
ENST00000520168.5
ENST00000260130.9
syndecan binding protein
chr1_+_111619751 15.45 ENST00000433097.5
ENST00000369709.3
RAP1A, member of RAS oncogene family
chr11_+_46332905 15.41 ENST00000343674.10
diacylglycerol kinase zeta
chr6_-_85642922 15.11 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr10_+_91798398 15.06 ENST00000371627.5
tankyrase 2
chr8_+_20197369 15.04 ENST00000276390.7
ENST00000519667.1
ATPase H+ transporting V1 subunit B2
chr12_-_57752345 15.03 ENST00000551800.5
ENST00000549606.5
ENST00000312990.10
cyclin dependent kinase 4
chr17_-_64506281 14.91 ENST00000225792.10
ENST00000585060.5
DEAD-box helicase 5
chr2_-_131093378 14.82 ENST00000409185.5
ENST00000389915.4
family with sequence similarity 168 member B
chr9_-_83980578 14.79 ENST00000376281.8
heterogeneous nuclear ribonucleoprotein K
chr12_-_46372763 14.72 ENST00000256689.10
solute carrier family 38 member 2
chr20_-_53593829 14.53 ENST00000371471.7
zinc finger protein 217
chr2_-_130509287 14.51 ENST00000615053.3
ENST00000631234.1
ENST00000451531.7
POTE ankyrin domain family member I
chr11_+_34051722 14.50 ENST00000341394.9
ENST00000389645.7
cell cycle associated protein 1
chrX_+_123961304 14.44 ENST00000371160.5
ENST00000435103.5
stromal antigen 2
chr1_-_150235943 14.39 ENST00000533654.5
acidic nuclear phosphoprotein 32 family member E
chr7_-_87219709 14.24 ENST00000257637.8
transmembrane protein 243
chr11_+_87037820 13.82 ENST00000340353.11
transmembrane protein 135
chr5_-_173328407 13.73 ENST00000265087.9
stanniocalcin 2
chr4_-_24584517 13.61 ENST00000336812.5
DEAH-box helicase 15
chr10_+_97426162 13.50 ENST00000334828.6
phosphoglycerate mutase 1
chr6_-_99568713 13.48 ENST00000520371.5
cyclin C
chr5_-_32174262 13.41 ENST00000265070.7
golgi phosphoprotein 3
chr3_-_149971109 13.35 ENST00000239940.11
profilin 2
chr1_-_35193135 12.92 ENST00000357214.6
splicing factor proline and glutamine rich
chr1_-_244864560 12.86 ENST00000444376.7
heterogeneous nuclear ribonucleoprotein U
chr10_+_5412542 12.65 ENST00000355029.9
neuroepithelial cell transforming 1
chr9_-_36276967 12.59 ENST00000396594.8
ENST00000543356.7
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr17_+_38870050 12.58 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr4_-_10116779 12.57 ENST00000499869.7
WD repeat domain 1
chr15_-_64162965 12.54 ENST00000300026.4
ENST00000681397.1
ENST00000681658.1
peptidylprolyl isomerase B
chr10_-_125160499 12.50 ENST00000494626.6
ENST00000337195.9
C-terminal binding protein 2
chr3_-_134374439 12.39 ENST00000513145.1
ENST00000249883.10
ENST00000422605.6
angiomotin like 2
chr11_+_842824 12.36 ENST00000397396.5
ENST00000397397.7
tetraspanin 4
chr14_+_90397019 12.22 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
calmodulin 1
chr7_-_88220025 12.09 ENST00000419179.5
ENST00000265729.7
sorcin
chr2_-_25878445 12.08 ENST00000336112.9
ENST00000435504.9
ASXL transcriptional regulator 2
chr5_+_75337211 12.08 ENST00000287936.9
ENST00000343975.9
3-hydroxy-3-methylglutaryl-CoA reductase
chr14_-_54489003 11.83 ENST00000554908.5
ENST00000616146.4
glia maturation factor beta
chr5_+_62306228 11.57 ENST00000381103.7
kinesin family member 2A
chr20_-_47355657 11.56 ENST00000311275.11
zinc finger MYND-type containing 8
chr2_-_9630491 11.53 ENST00000381844.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr12_-_48957445 11.42 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ADP ribosylation factor 3
chrX_-_20141810 11.39 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chrX_+_41334154 11.24 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr3_+_113747022 11.00 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATPase H+ transporting V1 subunit A
chr7_-_106284971 10.94 ENST00000681878.1
ENST00000679951.1
ENST00000680823.1
ENST00000222553.8
ENST00000679643.1
nicotinamide phosphoribosyltransferase
chr4_-_110198650 10.91 ENST00000394607.7
ELOVL fatty acid elongase 6
chr7_+_101154445 10.86 ENST00000337619.11
ENST00000429457.1
adaptor related protein complex 1 subunit sigma 1
chr6_-_79234619 10.70 ENST00000344726.9
ENST00000275036.11
high mobility group nucleosomal binding domain 3
chr12_-_118359639 10.63 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr8_-_48921419 10.63 ENST00000020945.4
snail family transcriptional repressor 2
chr3_-_47781837 10.62 ENST00000254480.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr4_-_22516001 10.32 ENST00000334304.10
adhesion G protein-coupled receptor A3
chr1_-_38859669 10.30 ENST00000373001.4
Ras related GTP binding C
chr18_+_9913979 10.28 ENST00000400000.7
ENST00000340541.4
VAMP associated protein A
chr15_-_101252040 10.06 ENST00000254190.4
chondroitin sulfate synthase 1
chr19_+_7395112 10.06 ENST00000319670.14
Rho/Rac guanine nucleotide exchange factor 18
chr17_+_40219276 10.03 ENST00000583268.1
ENST00000323571.9
WAS/WASL interacting protein family member 2
chr4_-_75673112 10.01 ENST00000395719.7
ENST00000677489.1
G3BP stress granule assembly factor 2
chr17_-_55421818 9.89 ENST00000262065.8
ENST00000649377.1
monocyte to macrophage differentiation associated
chr2_+_231708511 9.88 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
prothymosin alpha
chr6_+_70667770 9.80 ENST00000370452.7
ENST00000316999.9
small ArfGAP 1
chr17_+_30477362 9.58 ENST00000225724.9
ENST00000451249.7
ENST00000467337.6
ENST00000581721.5
ENST00000414833.2
golgi SNAP receptor complex member 1
chr2_+_36355712 9.58 ENST00000280527.7
cysteine rich transmembrane BMP regulator 1
chr3_-_57597325 9.57 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ADP ribosylation factor 4
chr1_-_77682639 9.55 ENST00000370801.8
ENST00000433749.5
zinc finger ZZ-type containing 3
chr3_+_169966764 9.44 ENST00000337002.9
ENST00000480708.5
SEC62 homolog, preprotein translocation factor
chr11_-_796185 9.26 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr5_+_112976757 9.06 ENST00000389063.3
decapping mRNA 2
chr20_-_37527723 9.04 ENST00000397135.1
ENST00000397137.5
BLCAP apoptosis inducing factor
chr4_+_41990496 8.84 ENST00000264451.12
solute carrier family 30 member 9
chr12_-_43806249 8.81 ENST00000548315.5
ENST00000552521.5
ENST00000546662.5
ENST00000548403.1
ENST00000546506.5
ENST00000395510.7
twinfilin actin binding protein 1
chr2_+_98608555 8.78 ENST00000409975.5
ENST00000357765.7
unc-50 inner nuclear membrane RNA binding protein
chr1_-_113812448 8.75 ENST00000612242.4
ENST00000261441.9
round spermatid basic protein 1
chr1_-_94927079 8.64 ENST00000370206.9
ENST00000394202.8
calponin 3
chr17_+_31936993 8.62 ENST00000322652.10
SUZ12 polycomb repressive complex 2 subunit
chr12_-_31792290 8.57 ENST00000340398.5
H3.5 histone
chr2_+_177212724 8.27 ENST00000677043.1
ENST00000677863.1
ENST00000676681.1
ENST00000678111.1
ENST00000676874.1
ENST00000676736.1
ENST00000411529.6
ENST00000435711.5
heterogeneous nuclear ribonucleoprotein A3
chr3_-_42804451 8.16 ENST00000418900.6
ENST00000321331.12
ENST00000430190.5
ENST00000648550.1
HIG1 hypoxia inducible domain family member 1A
novel protein
chr11_+_69641146 8.08 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr3_+_170222412 7.95 ENST00000295797.5
protein kinase C iota
chr2_+_241315882 7.93 ENST00000401990.5
ENST00000407971.5
ENST00000436795.5
ENST00000411484.5
ENST00000434955.5
ENST00000391971.7
ENST00000402092.6
ENST00000441533.5
ENST00000443492.5
ENST00000437066.5
ENST00000429791.5
septin 2
chr7_-_6484057 7.87 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr3_-_100401028 7.86 ENST00000284320.6
translocase of outer mitochondrial membrane 70
chr3_-_125375249 7.62 ENST00000484491.5
ENST00000492394.5
ENST00000471196.1
ENST00000468369.5
ENST00000485866.5
ENST00000360647.9
zinc finger protein 148
chr10_+_100347225 7.61 ENST00000370355.3
stearoyl-CoA desaturase
chr11_+_118572373 7.50 ENST00000392859.7
ENST00000264028.5
ENST00000614498.4
ENST00000359415.8
ENST00000534182.2
archain 1
chr2_-_47176453 7.39 ENST00000484408.5
ENST00000489742.1
ENST00000272298.12
ENST00000656538.1
ENST00000409563.5
ENST00000456319.6
ENST00000628793.2
calmodulin 2
chr19_+_36215096 7.33 ENST00000443387.3
zinc finger protein 146
chr9_-_36400260 7.28 ENST00000259605.11
ENST00000353739.8
ENST00000611646.4
ring finger protein 38
chr15_+_58987652 7.14 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr1_-_88992732 6.99 ENST00000413769.1
ENST00000321792.5
ENST00000370491.7
RBMX like 1
kynurenine aminotransferase 3
chr15_-_72783685 6.90 ENST00000456471.3
ENST00000311669.12
ADP dependent glucokinase
chr6_+_15246054 6.76 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr19_+_55640966 6.72 ENST00000590190.1
ENST00000325333.10
ENST00000585995.1
ENST00000592996.5
zinc finger protein 580
zinc finger protein 581
coiled-coil domain containing 106
chr12_+_120710421 6.66 ENST00000344651.5
unc-119 lipid binding chaperone B
chr15_-_78299570 6.59 ENST00000560569.5
ENST00000558459.5
ENST00000558311.5
ENST00000267973.7
WD repeat domain 61
chr1_-_77759797 6.49 ENST00000524778.1
ENST00000370794.7
ENST00000370793.5
ENST00000370792.7
ubiquitin specific peptidase 33
chr20_+_57351218 6.48 ENST00000371242.6
ENST00000527947.5
ENST00000395841.7
ribonucleic acid export 1
chr17_-_50397472 6.45 ENST00000576448.1
ENST00000225972.8
leucine rich repeat containing 59
chrX_+_81202066 6.37 ENST00000373212.6
SH3 domain binding glutamate rich protein like
chr1_-_211579064 6.36 ENST00000367001.5
solute carrier family 30 member 1
chr1_-_155241220 6.34 ENST00000368373.8
ENST00000427500.7
glucosylceramidase beta
chr3_-_30894661 6.33 ENST00000282538.10
ENST00000454381.3
glutamate decarboxylase like 1
chr1_+_155209213 6.27 ENST00000609421.1
metaxin 1
chr3_+_150603279 6.16 ENST00000615547.4
ENST00000477889.5
ENST00000471696.6
ENST00000485923.1
selenoprotein T
chr2_-_168247569 6.14 ENST00000355999.5
serine/threonine kinase 39
chr11_-_86069043 6.10 ENST00000532317.5
ENST00000528256.1
ENST00000393346.8
ENST00000526033.5
phosphatidylinositol binding clathrin assembly protein
chr22_-_38872206 6.01 ENST00000407418.8
ENST00000216083.6
chromobox 6
chr12_+_12611839 6.00 ENST00000228865.3
cAMP responsive element binding protein like 2
chr20_-_63568074 5.99 ENST00000427522.6
helicase with zinc finger 2
chr1_+_93448155 5.97 ENST00000370253.6
formin binding protein 1 like
chr1_-_205750167 5.95 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr7_-_94004345 5.94 ENST00000222547.8
ENST00000433727.5
Bet1 golgi vesicular membrane trafficking protein
chr19_-_18281612 5.81 ENST00000252818.5
JunD proto-oncogene, AP-1 transcription factor subunit
chr19_+_45507470 5.80 ENST00000245932.11
ENST00000592139.1
ENST00000590603.1
vasodilator stimulated phosphoprotein
chr3_+_61561561 5.79 ENST00000474889.6
protein tyrosine phosphatase receptor type G
chr6_+_36594354 5.76 ENST00000373715.11
serine and arginine rich splicing factor 3
chr2_-_202911621 5.74 ENST00000261015.5
WD repeat domain 12
chr17_+_2593628 5.65 ENST00000397195.10
platelet activating factor acetylhydrolase 1b regulatory subunit 1
chr8_-_37899454 5.65 ENST00000522727.5
ENST00000287263.8
ENST00000330843.9
RAB11 family interacting protein 1
chr10_-_33334625 5.63 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr12_-_101830926 5.57 ENST00000299314.12
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr2_+_197500371 5.45 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr17_+_51153551 5.42 ENST00000393196.8
ENST00000336097.7
ENST00000480143.5
ENST00000511355.5
ENST00000393193.6
ENST00000376392.10
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
chr1_+_35883189 5.41 ENST00000674304.1
ENST00000373204.6
ENST00000674426.1
argonaute RISC component 1
chr9_+_113221528 5.34 ENST00000374212.5
solute carrier family 31 member 1
chr3_-_185938006 5.29 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr17_+_62458641 5.22 ENST00000582809.5
tousled like kinase 2
chr10_+_91923762 5.14 ENST00000265990.11
B-TFIID TATA-box binding protein associated factor 1
chr2_+_200305976 5.09 ENST00000358677.9
spermatogenesis associated serine rich 2 like
chr2_+_119759875 4.97 ENST00000263708.7
protein tyrosine phosphatase non-receptor type 4
chr21_-_33588624 4.94 ENST00000437395.5
ENST00000453626.5
ENST00000303113.10
ENST00000303071.10
ENST00000432378.5
DNA replication fork stabilization factor DONSON
chr4_+_159267737 4.87 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chrX_-_41922992 4.86 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
calcium/calmodulin dependent serine protein kinase
chr22_-_21867610 4.84 ENST00000215832.11
ENST00000398822.7
mitogen-activated protein kinase 1
chr6_-_107958165 4.73 ENST00000369002.9
SEC63 homolog, protein translocation regulator
chr2_+_190880834 4.71 ENST00000338435.8
glutaminase
chrX_+_28587411 4.67 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chr3_-_150546403 4.63 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr9_+_75088498 4.60 ENST00000346234.7
osteoclast stimulating factor 1
chr20_+_50510321 4.59 ENST00000541713.5
ENST00000371621.5
protein tyrosine phosphatase non-receptor type 1
chr16_+_30762289 4.57 ENST00000566811.5
ENST00000565995.5
ENST00000563683.5
ENST00000357890.9
ENST00000324685.11
ENST00000565931.1
ring finger protein 40
chr1_-_41918858 4.51 ENST00000372583.6
HIVEP zinc finger 3
chr13_+_42272134 4.41 ENST00000025301.4
A-kinase anchoring protein 11
chr6_+_116280098 4.37 ENST00000643175.1
ENST00000452085.7
dermatan sulfate epimerase
chr3_-_11720728 4.35 ENST00000445411.5
ENST00000273038.7
vestigial like family member 4
chr2_+_105744876 4.35 ENST00000233154.9
ENST00000451463.6
NCK adaptor protein 2
chr4_-_39638846 4.32 ENST00000295958.10
small integral membrane protein 14
chr19_+_41219177 4.23 ENST00000301178.9
AXL receptor tyrosine kinase
chr3_+_19947074 4.19 ENST00000273047.9
RAB5A, member RAS oncogene family
chr2_-_9423190 4.08 ENST00000497105.1
ENST00000360635.7
ENST00000359712.7
integrin subunit beta 1 binding protein 1
chr7_+_116672187 3.99 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chrX_-_75156272 3.85 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ATP binding cassette subfamily B member 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
15.6 77.8 GO:0019322 pentose biosynthetic process(GO:0019322)
8.4 25.3 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
6.5 32.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
6.2 18.6 GO:0002368 B cell cytokine production(GO:0002368)
5.4 21.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
5.1 25.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
5.0 15.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
4.6 18.4 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
4.4 26.6 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
4.2 16.6 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976)
4.0 16.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
3.9 15.4 GO:0097327 response to antineoplastic agent(GO:0097327)
3.7 14.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
3.5 10.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
3.5 24.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
3.4 10.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
3.4 13.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164)
3.3 43.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
3.2 42.1 GO:0090168 Golgi reassembly(GO:0090168)
3.1 12.6 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
3.1 12.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
3.0 15.0 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
3.0 3.0 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
2.9 11.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
2.7 19.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
2.6 15.8 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
2.4 16.8 GO:0090204 protein localization to nuclear pore(GO:0090204)
2.2 13.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.2 8.8 GO:0030047 actin modification(GO:0030047)
2.2 6.6 GO:0034729 histone H3-K79 methylation(GO:0034729)
2.2 12.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
2.1 6.3 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
2.1 14.7 GO:0032328 alanine transport(GO:0032328)
2.1 16.7 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
2.0 6.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
2.0 28.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.0 5.9 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
1.9 5.7 GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176)
1.9 7.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.9 5.6 GO:0016256 N-glycan processing to lysosome(GO:0016256)
1.7 12.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.6 4.8 GO:0019858 cytosine metabolic process(GO:0019858)
1.6 28.3 GO:0036010 protein localization to endosome(GO:0036010)
1.5 24.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
1.5 6.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
1.5 16.7 GO:0051451 myoblast migration(GO:0051451)
1.5 13.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.5 28.4 GO:0032486 Rap protein signal transduction(GO:0032486)
1.5 11.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.4 11.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.4 1.4 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
1.4 10.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.4 12.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.3 7.9 GO:0048194 Golgi vesicle budding(GO:0048194)
1.3 18.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
1.3 6.4 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
1.3 12.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.2 13.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.2 12.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.2 9.6 GO:0045176 apical protein localization(GO:0045176)
1.2 3.6 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.2 7.0 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.2 5.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
1.1 3.4 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
1.1 13.5 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.1 13.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.1 14.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.0 6.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.0 20.8 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.0 3.1 GO:0030185 nitric oxide transport(GO:0030185)
1.0 9.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.0 8.9 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.0 14.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.9 7.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.9 2.7 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.9 3.5 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.8 23.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.8 3.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.8 10.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.8 5.6 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.8 7.9 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.8 4.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.8 10.9 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.8 25.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.8 5.3 GO:0015677 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.8 2.3 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.7 5.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.7 8.1 GO:0033327 Leydig cell differentiation(GO:0033327) response to UV-A(GO:0070141)
0.7 2.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.7 22.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.7 4.2 GO:0048549 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.7 12.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.7 4.2 GO:0051036 regulation of endosome size(GO:0051036)
0.7 26.9 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.7 21.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.7 10.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.6 15.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.6 3.8 GO:0097338 response to clozapine(GO:0097338)
0.6 2.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.6 5.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5 6.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.5 13.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.5 3.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.5 6.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.5 4.0 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.5 6.5 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 12.6 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.5 1.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 1.0 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.5 21.8 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.5 3.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.4 1.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.4 16.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.4 5.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.4 3.9 GO:0015886 heme transport(GO:0015886)
0.4 10.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.4 2.1 GO:0016240 autophagosome docking(GO:0016240)
0.4 3.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 1.2 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.4 8.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 3.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 2.3 GO:0010265 SCF complex assembly(GO:0010265)
0.4 8.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.4 19.0 GO:0007566 embryo implantation(GO:0007566)
0.3 2.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 3.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 9.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 10.6 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.3 5.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.0 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 19.2 GO:0021762 substantia nigra development(GO:0021762)
0.3 17.0 GO:0006611 protein export from nucleus(GO:0006611)
0.3 2.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.3 23.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 1.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.3 14.4 GO:0043486 histone exchange(GO:0043486)
0.3 18.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.3 1.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.7 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 18.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 1.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 20.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 0.7 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.2 14.5 GO:0001895 retina homeostasis(GO:0001895)
0.2 9.0 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.2 10.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 8.8 GO:0035329 hippo signaling(GO:0035329)
0.2 0.6 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 6.7 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 9.9 GO:0019835 cytolysis(GO:0019835)
0.2 6.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 2.5 GO:0043622 cortical microtubule organization(GO:0043622) negative regulation of p38MAPK cascade(GO:1903753)
0.2 3.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 16.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.2 1.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 7.6 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2 1.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 6.7 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.2 3.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 6.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 5.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 4.7 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 6.0 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 20.2 GO:0002576 platelet degranulation(GO:0002576)
0.1 8.3 GO:0071806 protein transmembrane transport(GO:0071806)
0.1 7.9 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.8 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1 4.9 GO:0033260 nuclear DNA replication(GO:0033260)
0.1 14.4 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1 3.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 6.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 6.9 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 0.9 GO:0060033 anatomical structure regression(GO:0060033)
0.1 10.5 GO:0008360 regulation of cell shape(GO:0008360)
0.1 2.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 6.3 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.0 9.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.6 GO:0070828 heterochromatin organization(GO:0070828)
0.0 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 8.7 GO:0009416 response to light stimulus(GO:0009416)
0.0 4.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 7.5 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 1.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.5 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.8 GO:0021766 hippocampus development(GO:0021766)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 25.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
2.7 13.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
2.6 18.2 GO:0030905 retromer, tubulation complex(GO:0030905)
2.5 12.6 GO:0042643 actomyosin, actin portion(GO:0042643)
2.5 37.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.4 26.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
2.2 6.6 GO:0055087 Ski complex(GO:0055087)
2.2 21.6 GO:0071439 clathrin complex(GO:0071439)
2.1 12.6 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.1 25.0 GO:0071203 WASH complex(GO:0071203)
2.1 18.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
2.0 11.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.9 9.6 GO:0005797 Golgi medial cisterna(GO:0005797)
1.7 28.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.7 17.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.7 12.1 GO:0044326 dendritic spine neck(GO:0044326)
1.6 26.2 GO:0016600 flotillin complex(GO:0016600)
1.6 14.4 GO:0042382 paraspeckles(GO:0042382)
1.6 10.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.2 6.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.1 10.2 GO:0097443 sorting endosome(GO:0097443)
1.1 15.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.1 2.1 GO:1903349 omegasome membrane(GO:1903349)
1.0 3.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.0 7.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.0 8.6 GO:0001739 sex chromatin(GO:0001739)
1.0 5.7 GO:0070545 PeBoW complex(GO:0070545)
0.9 16.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.9 16.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.9 4.6 GO:0033503 HULC complex(GO:0033503)
0.9 17.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.8 6.5 GO:0030891 VCB complex(GO:0030891)
0.8 12.5 GO:0097470 ribbon synapse(GO:0097470)
0.8 14.4 GO:0000812 Swr1 complex(GO:0000812)
0.7 5.8 GO:0035976 AP1 complex(GO:0035976)
0.7 15.1 GO:0000242 pericentriolar material(GO:0000242)
0.7 15.5 GO:0071141 SMAD protein complex(GO:0071141)
0.6 7.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.6 42.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.6 5.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.6 19.0 GO:0000421 autophagosome membrane(GO:0000421)
0.5 26.6 GO:0031941 filamentous actin(GO:0031941)
0.5 19.1 GO:0035861 site of double-strand break(GO:0035861)
0.5 4.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.5 28.7 GO:0031519 PcG protein complex(GO:0031519)
0.5 8.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 9.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 9.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.5 33.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 32.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.4 3.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 12.9 GO:0016514 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.4 4.9 GO:0005652 nuclear lamina(GO:0005652)
0.4 11.6 GO:0097228 sperm principal piece(GO:0097228)
0.3 56.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 4.0 GO:0009925 basal plasma membrane(GO:0009925)
0.3 4.2 GO:0033643 host cell part(GO:0033643)
0.3 107.2 GO:0031965 nuclear membrane(GO:0031965)
0.3 3.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 14.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 1.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 24.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 26.7 GO:0005882 intermediate filament(GO:0005882)
0.2 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 5.9 GO:0031985 Golgi cisterna(GO:0031985)
0.2 10.9 GO:0043198 dendritic shaft(GO:0043198)
0.2 6.7 GO:0035869 ciliary transition zone(GO:0035869)
0.2 3.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 10.0 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.2 7.3 GO:0036126 sperm flagellum(GO:0036126)
0.2 5.8 GO:0031527 filopodium membrane(GO:0031527)
0.2 17.9 GO:0005903 brush border(GO:0005903)
0.2 4.8 GO:0031143 pseudopodium(GO:0031143)
0.2 2.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 3.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 2.5 GO:0043219 lateral loop(GO:0043219)
0.2 97.5 GO:0005925 focal adhesion(GO:0005925)
0.2 13.2 GO:0031902 late endosome membrane(GO:0031902)
0.1 6.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 30.0 GO:0016324 apical plasma membrane(GO:0016324)
0.1 4.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 12.4 GO:0030027 lamellipodium(GO:0030027)
0.1 10.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 16.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 22.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 14.1 GO:0000922 spindle pole(GO:0000922)
0.1 2.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 8.2 GO:0070469 respiratory chain(GO:0070469)
0.1 6.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 4.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 6.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 7.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 6.7 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 7.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 76.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 3.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 11.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
6.4 25.8 GO:0004802 transketolase activity(GO:0004802)
6.2 18.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
5.3 15.8 GO:0005137 interleukin-5 receptor binding(GO:0005137)
5.1 25.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
4.6 18.4 GO:0002060 purine nucleobase binding(GO:0002060)
3.6 18.2 GO:1990460 leptin receptor binding(GO:1990460)
3.6 25.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
3.5 24.8 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
3.4 10.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
3.2 19.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
3.2 9.6 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
3.1 9.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
3.0 12.1 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
3.0 9.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
2.8 11.2 GO:0043273 CTPase activity(GO:0043273)
2.7 13.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.6 7.9 GO:0005046 KDEL sequence binding(GO:0005046)
2.5 14.9 GO:0035500 MH2 domain binding(GO:0035500)
2.4 16.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
2.3 7.0 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
2.2 10.9 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
2.1 6.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
2.0 27.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
2.0 21.6 GO:0032051 clathrin light chain binding(GO:0032051)
1.9 7.6 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.8 12.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.8 7.1 GO:0032184 SUMO polymer binding(GO:0032184)
1.7 26.9 GO:0030215 semaphorin receptor binding(GO:0030215)
1.7 23.2 GO:0046790 virion binding(GO:0046790)
1.6 6.3 GO:0004348 glucosylceramidase activity(GO:0004348)
1.5 11.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.5 16.1 GO:0004673 protein histidine kinase activity(GO:0004673)
1.5 4.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.5 20.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.4 5.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.4 8.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.4 20.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.4 10.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.2 3.6 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.1 16.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.0 12.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
1.0 3.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
1.0 13.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.9 36.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.9 20.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.9 3.5 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.9 18.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.8 22.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.8 3.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.8 21.1 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.8 4.7 GO:0004359 glutaminase activity(GO:0004359)
0.7 24.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.7 5.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.7 16.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.6 17.9 GO:0070410 co-SMAD binding(GO:0070410)
0.6 8.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 5.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 6.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.5 35.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.5 2.7 GO:0070051 fibrinogen binding(GO:0070051)
0.5 1.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756)
0.5 11.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.5 43.8 GO:0019003 GDP binding(GO:0019003)
0.5 23.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 3.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 21.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.5 19.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 11.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.5 3.9 GO:0015232 heme transporter activity(GO:0015232)
0.5 1.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.5 5.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 19.7 GO:0003785 actin monomer binding(GO:0003785)
0.4 5.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.4 7.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.4 13.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.4 22.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 6.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 15.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4 16.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 8.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 1.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.4 4.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 5.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 7.9 GO:0004697 protein kinase C activity(GO:0004697)
0.4 5.7 GO:0043274 phospholipase binding(GO:0043274)
0.4 23.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.4 6.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 1.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.4 6.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 5.8 GO:0005522 profilin binding(GO:0005522)
0.3 6.0 GO:0097016 L27 domain binding(GO:0097016)
0.3 12.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 2.4 GO:0050733 RS domain binding(GO:0050733)
0.3 9.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 4.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 9.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 4.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 14.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.3 25.0 GO:0008565 protein transporter activity(GO:0008565)
0.2 3.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 3.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 10.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 1.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 3.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 12.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 9.3 GO:0043022 ribosome binding(GO:0043022)
0.2 36.7 GO:0044325 ion channel binding(GO:0044325)
0.2 2.2 GO:0051400 BH domain binding(GO:0051400)
0.2 2.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 14.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 16.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 3.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 4.8 GO:0004707 MAP kinase activity(GO:0004707)
0.2 4.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 11.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 49.5 GO:0045296 cadherin binding(GO:0045296)
0.1 17.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 10.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 23.8 GO:0051015 actin filament binding(GO:0051015)
0.1 11.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 5.1 GO:0004386 helicase activity(GO:0004386)
0.1 2.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 14.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 8.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 10.4 GO:0020037 heme binding(GO:0020037)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 8.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 5.3 GO:0043130 ubiquitin binding(GO:0043130)
0.1 12.4 GO:0003823 antigen binding(GO:0003823)
0.0 5.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 4.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 26.5 GO:0003723 RNA binding(GO:0003723)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 34.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.0 40.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.8 39.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.8 15.8 PID IL5 PATHWAY IL5-mediated signaling events
0.7 32.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.5 18.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 28.1 PID ARF6 PATHWAY Arf6 signaling events
0.5 27.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.4 5.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 26.0 PID PLK1 PATHWAY PLK1 signaling events
0.4 18.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.4 13.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 24.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 24.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 10.0 PID REELIN PATHWAY Reelin signaling pathway
0.3 36.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 3.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 42.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 4.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 4.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 3.8 PID IL3 PATHWAY IL3-mediated signaling events
0.2 19.7 PID E2F PATHWAY E2F transcription factor network
0.2 17.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 7.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 6.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 9.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 9.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 17.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 24.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.7 67.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.4 21.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.4 27.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.4 18.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
1.1 23.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.1 28.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.9 19.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.9 26.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.7 1.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.7 7.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.7 21.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 29.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.5 11.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 16.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.5 3.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 17.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 6.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5 11.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.5 10.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 17.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 3.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 24.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.4 20.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.4 15.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.4 11.6 REACTOME KINESINS Genes involved in Kinesins
0.4 11.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 8.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 10.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 5.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 25.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3 16.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 34.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 12.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 14.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 9.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 13.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 11.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 14.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 54.4 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.2 4.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 4.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 2.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 18.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 11.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 6.3 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 29.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 24.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 7.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 10.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 12.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 4.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 5.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 4.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors