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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GLI2

Z-value: 8.76

Motif logo

Transcription factors associated with GLI2

Gene Symbol Gene ID Gene Info
ENSG00000074047.22 GLI2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI2hg38_v1_chr2_+_120735848_120735899-0.643.3e-26Click!

Activity profile of GLI2 motif

Sorted Z-values of GLI2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_120496075 24.86 ENST00000548214.1
ENST00000392508.2
dynein light chain LC8-type 1
chr21_-_39183398 23.29 ENST00000331573.8
proteasome assembly chaperone 1
chr12_+_120496101 22.24 ENST00000550178.1
ENST00000550845.5
ENST00000549989.1
ENST00000552870.1
ENST00000242577.11
dynein light chain LC8-type 1
chr3_-_63863791 21.95 ENST00000464327.2
ENST00000295899.10
ENST00000469584.5
THO complex 7
chr12_-_2877113 21.39 ENST00000627656.2
ENST00000359843.8
forkhead box M1
chr1_+_220094086 21.05 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr18_+_12948001 20.88 ENST00000399892.7
ENST00000585730.5
ENST00000589446.5
ENST00000587761.1
SEH1 like nucleoporin
chr22_+_38982370 20.08 ENST00000402182.7
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
chr21_-_39183466 19.24 ENST00000380900.2
proteasome assembly chaperone 1
chr3_-_49029378 19.12 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr19_-_42302766 18.95 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr1_+_154974672 18.04 ENST00000308987.6
ENST00000368436.1
CDC28 protein kinase regulatory subunit 1B
chr20_-_34303345 17.67 ENST00000217426.7
adenosylhomocysteinase
chr10_-_119178791 17.63 ENST00000298510.4
peroxiredoxin 3
chr12_-_108731505 17.62 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr12_-_2876986 17.31 ENST00000342628.6
ENST00000361953.7
forkhead box M1
chr1_+_154974653 17.29 ENST00000368439.5
CDC28 protein kinase regulatory subunit 1B
chr20_+_3796288 16.70 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr1_-_11055820 16.68 ENST00000490101.1
spermidine synthase
chr2_+_186506713 16.24 ENST00000445547.1
zinc finger CCCH-type containing 15
chr9_+_107284053 16.19 ENST00000416373.6
RAD23 homolog B, nucleotide excision repair protein
chr2_+_74206384 15.32 ENST00000678623.1
ENST00000678731.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr12_-_110445540 15.30 ENST00000547365.1
actin related protein 2/3 complex subunit 3
chr19_+_572529 15.03 ENST00000679472.1
ENST00000680552.1
ENST00000680065.1
ENST00000573216.5
basigin (Ok blood group)
chr19_-_10420121 15.01 ENST00000593124.1
cell division cycle 37, HSP90 cochaperone
chr1_-_6360677 14.86 ENST00000377845.7
acyl-CoA thioesterase 7
chr19_-_42302576 14.82 ENST00000262890.8
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chrX_-_108091520 14.65 ENST00000340200.5
ENST00000217958.8
ENST00000372296.5
ENST00000372295.5
ENST00000361815.9
proteasome 26S subunit, non-ATPase 10
chr12_-_122227449 14.62 ENST00000650715.1
diablo IAP-binding mitochondrial protein
chr12_-_122227491 14.53 ENST00000475784.1
ENST00000645606.1
novel protein
chr22_+_38982341 14.15 ENST00000407298.7
ENST00000333467.4
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
chr11_-_57335854 14.10 ENST00000529002.2
ENST00000278412.7
structure specific recognition protein 1
chr16_+_30064274 13.82 ENST00000563060.6
aldolase, fructose-bisphosphate A
chr14_+_24136152 13.81 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr1_-_25906457 13.67 ENST00000426559.6
stathmin 1
chr5_-_90409720 13.66 ENST00000522864.5
ENST00000283122.8
ENST00000522083.5
ENST00000522565.5
ENST00000522842.1
centrin 3
chr8_+_26291758 13.46 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chrX_+_23664251 13.37 ENST00000379349.5
peroxiredoxin 4
chr19_+_48325323 13.25 ENST00000596315.5
epithelial membrane protein 3
chrX_+_12791353 13.19 ENST00000380663.7
ENST00000398491.6
ENST00000380668.10
ENST00000489404.5
phosphoribosyl pyrophosphate synthetase 2
chrX_-_109733249 13.14 ENST00000469796.7
ENST00000672401.1
ENST00000671846.1
acyl-CoA synthetase long chain family member 4
chr1_-_150974867 13.09 ENST00000271688.10
ceramide synthase 2
chr1_-_150974823 13.08 ENST00000361419.9
ENST00000368954.10
ceramide synthase 2
chr1_+_1001002 13.07 ENST00000624697.4
ENST00000624652.1
ISG15 ubiquitin like modifier
chr17_-_75182536 13.02 ENST00000578238.2
small ubiquitin like modifier 2
chr11_-_71448315 12.95 ENST00000525346.5
ENST00000531364.5
ENST00000529990.5
ENST00000527316.5
ENST00000355527.8
ENST00000407721.6
7-dehydrocholesterol reductase
chr8_-_63038788 12.85 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr16_+_30064462 12.82 ENST00000412304.6
aldolase, fructose-bisphosphate A
chr7_-_95435329 12.72 ENST00000633192.1
paraoxonase 2
chr12_-_47705971 12.68 ENST00000380650.4
RNA polymerase II associated protein 3
chr19_-_42302690 12.65 ENST00000596265.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chrX_+_71283577 12.64 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chr19_+_572586 12.50 ENST00000333511.9
ENST00000353555.9
ENST00000680326.1
ENST00000618006.4
ENST00000614867.2
basigin (Ok blood group)
chr19_-_42302292 12.44 ENST00000594989.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr12_+_71754834 12.35 ENST00000261263.5
RAB21, member RAS oncogene family
chr1_-_31937769 12.32 ENST00000649841.1
ENST00000534796.5
protein tyrosine phosphatase 4A2
chr11_-_71448406 12.15 ENST00000682708.1
ENST00000683287.1
ENST00000683714.1
ENST00000682880.1
7-dehydrocholesterol reductase
chr17_-_81869934 12.10 ENST00000580685.5
Rho GDP dissociation inhibitor alpha
chr20_+_44885679 12.06 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr14_-_24146596 12.00 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
proteasome activator subunit 2
chr1_-_39575686 11.97 ENST00000677006.1
ENST00000678625.1
ENST00000677609.1
poly(A) binding protein cytoplasmic 4
chr12_-_47705990 11.66 ENST00000432584.7
ENST00000005386.8
RNA polymerase II associated protein 3
chr3_-_72446623 11.63 ENST00000477973.4
RING1 and YY1 binding protein
chr7_+_26201705 11.36 ENST00000396386.7
ENST00000456948.5
ENST00000409747.5
chromobox 3
chrX_+_47223009 11.15 ENST00000518022.5
ENST00000276052.10
cyclin dependent kinase 16
chr2_-_168890368 11.14 ENST00000282074.7
SPC25 component of NDC80 kinetochore complex
chr16_+_30053123 11.13 ENST00000395248.6
ENST00000575627.5
ENST00000566897.6
ENST00000568435.6
ENST00000338110.11
ENST00000562240.1
novel protein
chrX_-_109733220 11.08 ENST00000672282.1
ENST00000340800.7
acyl-CoA synthetase long chain family member 4
chr17_+_1829981 11.08 ENST00000254719.10
replication protein A1
chr16_+_89923333 10.98 ENST00000315491.12
ENST00000555576.5
ENST00000554336.5
ENST00000553967.1
tubulin beta 3 class III
chrX_-_109733292 10.97 ENST00000682031.1
ENST00000502391.6
ENST00000508092.5
ENST00000348502.10
acyl-CoA synthetase long chain family member 4
chr17_-_42016680 10.94 ENST00000674497.1
DnaJ heat shock protein family (Hsp40) member C7
chr11_+_46381645 10.89 ENST00000617138.4
ENST00000395566.9
ENST00000395569.8
midkine
chr19_-_1095261 10.87 ENST00000585838.2
ENST00000586746.5
ENST00000619917.4
ENST00000615234.5
ENST00000612655.4
RNA polymerase II, I and III subunit E
chr19_+_48321454 10.78 ENST00000599704.5
epithelial membrane protein 3
chr11_+_61792878 10.67 ENST00000305885.3
ENST00000535723.1
flap structure-specific endonuclease 1
chr19_+_49677055 10.67 ENST00000534465.6
ENST00000391851.8
ENST00000610806.4
protein arginine methyltransferase 1
chr5_-_132777866 10.56 ENST00000448933.5
septin 8
chr14_+_54396964 10.53 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr7_-_54759182 10.49 ENST00000450622.1
ENST00000352861.9
ENST00000395535.7
SEC61 translocon subunit gamma
chr19_+_46602050 10.47 ENST00000599839.5
ENST00000596362.1
calmodulin 3
chr17_+_42609641 10.40 ENST00000681413.1
ENST00000251413.8
ENST00000591509.5
tubulin gamma 1
chr11_+_34916611 10.39 ENST00000227868.9
ENST00000430469.6
ENST00000533262.1
pyruvate dehydrogenase complex component X
chr5_-_10761156 10.34 ENST00000432074.2
ENST00000230895.11
death associated protein
chr11_+_65041203 10.29 ENST00000652489.1
ENST00000674184.1
SAC3 domain containing 1
chr16_-_23596277 10.24 ENST00000562133.5
ENST00000570319.5
ENST00000007516.8
NADH:ubiquinone oxidoreductase subunit AB1
chr19_+_49677228 10.09 ENST00000454376.7
ENST00000524771.5
protein arginine methyltransferase 1
chr1_+_156786875 10.05 ENST00000526188.5
ENST00000454659.1
proline rich mitotic checkpoint control factor
chr2_+_201071984 10.05 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr17_-_42018488 10.03 ENST00000589773.5
ENST00000674214.1
DnaJ heat shock protein family (Hsp40) member C7
chr10_+_5692792 9.84 ENST00000645567.1
transcription activation suppressor family member 2
chr7_-_95434951 9.78 ENST00000478801.5
ENST00000469926.5
ENST00000493290.5
ENST00000222572.8
ENST00000633531.1
ENST00000490778.5
ENST00000433091.6
paraoxonase 2
chr3_-_58433810 9.77 ENST00000474765.1
ENST00000485460.5
ENST00000302746.11
ENST00000383714.8
pyruvate dehydrogenase E1 subunit beta
chrX_+_23667461 9.77 ENST00000379341.9
ENST00000379331.3
peroxiredoxin 4
chr3_+_184362599 9.76 ENST00000455712.5
RNA polymerase II, I and III subunit H
chr14_-_94390650 9.69 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr5_-_132777371 9.57 ENST00000620483.4
septin 8
chr1_+_26543106 9.54 ENST00000530003.5
ribosomal protein S6 kinase A1
chr10_+_74176537 9.43 ENST00000672394.1
adenosine kinase
chr11_+_65040895 9.43 ENST00000531072.1
ENST00000398846.6
SAC3 domain containing 1
chr11_-_118679637 9.40 ENST00000264029.9
ENST00000397925.2
trehalase
chr11_-_67401782 9.39 ENST00000527663.6
ENST00000312989.11
ENST00000376745.9
ENST00000358239.8
protein phosphatase 1 catalytic subunit alpha
chr16_-_69334871 9.39 ENST00000562949.1
novel protein, COG8-PDF readthrough
chr4_-_89837076 9.37 ENST00000506691.1
synuclein alpha
chr19_-_58558871 9.36 ENST00000595957.5
ubiquitin conjugating enzyme E2 M
chr6_+_30717433 9.28 ENST00000681435.1
tubulin beta class I
chr14_-_94390614 9.23 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr12_-_120250145 9.21 ENST00000458477.6
paxillin
chr14_-_94390667 9.15 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr15_-_68820861 9.13 ENST00000560303.1
ENST00000465139.6
acidic nuclear phosphoprotein 32 family member A
chr17_+_7583828 9.07 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr3_+_23805941 9.06 ENST00000306627.8
ENST00000346855.7
ubiquitin conjugating enzyme E2 E1
chr10_+_14838288 9.02 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
novel protein
heat shock protein family A (Hsp70) member 14
chr19_+_16067526 8.94 ENST00000646974.2
tropomyosin 4
chr16_+_67029133 8.90 ENST00000290858.11
ENST00000412916.7
ENST00000564034.6
core-binding factor subunit beta
chr17_+_82237134 8.90 ENST00000583025.1
solute carrier family 16 member 3
chr16_-_2251562 8.90 ENST00000562238.5
ENST00000301729.9
ENST00000566379.1
enoyl-CoA delta isomerase 1
chr10_-_125006006 8.86 ENST00000334808.10
C-terminal binding protein 2
chr6_+_142301926 8.84 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr12_+_52069967 8.80 ENST00000336854.9
ENST00000550604.1
ENST00000553049.5
ENST00000548915.1
autophagy related 101
chr17_+_78168565 8.67 ENST00000225777.8
ENST00000585591.5
ENST00000589711.1
ENST00000588282.5
ENST00000589168.1
synaptogyrin 2
chr6_+_125219804 8.63 ENST00000524679.1
TPD52 like 1
chr17_-_82037677 8.61 ENST00000581584.5
ENST00000577712.5
ENST00000582900.5
ENST00000579155.1
ENST00000306869.7
dicarbonyl and L-xylulose reductase
chr11_+_66052331 8.60 ENST00000528302.5
ENST00000322535.11
ENST00000524627.5
ENST00000533595.5
ENST00000530322.5
splicing factor 3b subunit 2
chr2_-_3558280 8.59 ENST00000315212.4
ribonuclease H1
chr3_+_184363427 8.56 ENST00000429568.1
RNA polymerase II, I and III subunit H
chr6_+_44247087 8.55 ENST00000353801.7
ENST00000371646.10
heat shock protein 90 alpha family class B member 1
chr11_-_414948 8.48 ENST00000530494.1
ENST00000528209.5
ENST00000528058.1
ENST00000431843.7
single Ig and TIR domain containing
chrX_-_109733181 8.43 ENST00000673016.1
acyl-CoA synthetase long chain family member 4
chr10_+_74176741 8.39 ENST00000673027.1
ENST00000372734.5
ENST00000541550.6
adenosine kinase
chr3_+_184363387 8.36 ENST00000452961.5
RNA polymerase II, I and III subunit H
chr20_+_36574535 8.33 ENST00000558530.1
ENST00000558028.5
ENST00000611732.4
ENST00000560025.1
TGIF2-RAB5IF readthrough
TGFB induced factor homeobox 2
chr1_-_25906931 8.30 ENST00000357865.6
stathmin 1
chr8_-_143939543 8.26 ENST00000345136.8
plectin
chr1_-_25906411 8.23 ENST00000455785.7
stathmin 1
chr12_-_56316002 8.17 ENST00000547423.5
ENST00000548360.1
ENST00000551475.5
novel protein
canopy FGF signaling regulator 2
chrX_+_65667645 8.09 ENST00000360270.7
moesin
chr6_-_106975309 8.07 ENST00000615659.1
CD24 molecule
chr12_-_89352487 8.05 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr11_-_34916310 8.01 ENST00000395787.4
APAF1 interacting protein
chr12_+_51239278 8.00 ENST00000551313.1
DAZ associated protein 2
chr20_+_63696643 7.95 ENST00000369996.3
TNF receptor superfamily member 6b
chr16_-_11587450 7.94 ENST00000571688.5
lipopolysaccharide induced TNF factor
chr3_+_23917170 7.92 ENST00000643707.1
ribosomal protein L15
chr10_+_74151202 7.85 ENST00000672429.1
ENST00000539909.6
ENST00000286621.7
adenosine kinase
chr19_+_10996221 7.82 ENST00000647268.1
ENST00000643857.1
ENST00000646183.1
ENST00000646746.1
ENST00000643534.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr11_+_18394552 7.82 ENST00000543445.5
ENST00000430553.6
ENST00000396222.6
ENST00000535451.5
ENST00000422447.8
lactate dehydrogenase A
chr3_+_184363351 7.77 ENST00000443489.5
RNA polymerase II, I and III subunit H
chr11_+_18394586 7.75 ENST00000227157.8
ENST00000478970.6
ENST00000495052.5
lactate dehydrogenase A
chr9_+_33265013 7.72 ENST00000223500.9
charged multivesicular body protein 5
chr4_-_7068033 7.68 ENST00000264954.5
GrpE like 1, mitochondrial
chr7_+_23106267 7.68 ENST00000409689.5
ENST00000410047.1
kelch like family member 7
chr19_+_10871516 7.67 ENST00000327064.9
ENST00000588947.5
coactivator associated arginine methyltransferase 1
chr19_-_55280194 7.65 ENST00000588971.1
ENST00000255631.9
ENST00000587551.1
HSPA (Hsp70) binding protein 1
chr13_-_29595670 7.62 ENST00000380752.10
solute carrier family 7 member 1
chr12_-_76084666 7.56 ENST00000393263.7
ENST00000548044.5
ENST00000547704.5
ENST00000618691.5
ENST00000431879.7
ENST00000549596.5
ENST00000550934.5
ENST00000551600.5
ENST00000547479.5
ENST00000547773.5
ENST00000544816.5
ENST00000542344.5
ENST00000548273.5
nucleosome assembly protein 1 like 1
chr17_-_63842663 7.55 ENST00000613943.4
ENST00000448276.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr7_-_74254362 7.52 ENST00000352131.7
ENST00000055077.8
ENST00000621097.4
replication factor C subunit 2
chr4_+_94489030 7.49 ENST00000510099.5
PDZ and LIM domain 5
chr3_+_158105819 7.45 ENST00000480820.5
arginine and serine rich coiled-coil 1
chr14_-_24146314 7.44 ENST00000559056.5
proteasome activator subunit 2
chr22_-_50526337 7.42 ENST00000651490.1
ENST00000543927.6
thymidine phosphorylase
synthesis of cytochrome C oxidase 2
chr12_+_51238854 7.41 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr2_-_202911621 7.41 ENST00000261015.5
WD repeat domain 12
chr12_-_110450298 7.36 ENST00000426440.5
ENST00000228825.12
actin related protein 2/3 complex subunit 3
chr8_+_95133746 7.34 ENST00000315367.4
pleckstrin homology and FYVE domain containing 2
chr22_+_31092447 7.30 ENST00000455608.5
smoothelin
chr19_-_18941184 7.29 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr7_-_6826275 7.21 ENST00000316731.13
CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated
chr19_-_10503186 7.19 ENST00000592055.2
ENST00000171111.10
kelch like ECH associated protein 1
chr13_+_114235044 7.16 ENST00000252457.9
ENST00000375308.5
cell division cycle 16
chr17_+_43006740 7.12 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chr2_-_24085186 7.11 ENST00000335934.8
tumor protein p53 inducible protein 3
chr14_-_75063990 7.06 ENST00000555135.1
ENST00000357971.7
ENST00000553302.1
ENST00000238618.8
ENST00000555694.5
acylphosphatase 1
chrX_+_24054931 7.06 ENST00000253039.9
ENST00000423068.1
eukaryotic translation initiation factor 2 subunit gamma
chr19_-_54189550 7.05 ENST00000338624.10
ENST00000245615.6
membrane bound O-acyltransferase domain containing 7
chr12_-_124863783 6.99 ENST00000546215.5
ENST00000415380.6
ENST00000545493.1
ENST00000261693.11
ENST00000680596.1
scavenger receptor class B member 1
chr16_-_28495519 6.96 ENST00000569430.7
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr6_+_158168342 6.96 ENST00000648328.1
ENST00000607778.2
general transcription factor IIH subunit 5
chr5_-_150904789 6.92 ENST00000427179.5
zinc finger protein 300
chr5_-_150904971 6.92 ENST00000394226.2
ENST00000274599.10
ENST00000418587.6
ENST00000446148.6
zinc finger protein 300
chr19_+_58544045 6.91 ENST00000253024.10
ENST00000593582.5
tripartite motif containing 28
chr12_-_124863902 6.90 ENST00000339570.9
ENST00000680556.1
scavenger receptor class B member 1
chr4_-_76148382 6.87 ENST00000264883.8
ENST00000514987.5
ENST00000514901.5
nucleoporin 54
chr20_-_31722854 6.85 ENST00000307677.5
BCL2 like 1
chr1_-_19484635 6.85 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr14_-_49688201 6.84 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr1_+_86704892 6.83 ENST00000482504.1
SH3 domain containing GRB2 like, endophilin B1
chr7_+_6577416 6.74 ENST00000405731.7
ENST00000396713.6
ENST00000396707.6
ENST00000335965.11
ENST00000396709.5
ENST00000483589.5
ENST00000396706.2
zinc finger DHHC-type palmitoyltransferase 4
chr11_+_64241600 6.68 ENST00000535135.7
ENST00000652094.1
FKBP prolyl isomerase 2
chr15_-_49155574 6.64 ENST00000558843.5
ENST00000388901.10
ENST00000542928.5
ENST00000561248.1
ENST00000299259.10
COP9 signalosome subunit 2
chr5_-_7868995 6.61 ENST00000264669.10
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chr12_-_56315890 6.60 ENST00000551286.1
ENST00000549318.5
canopy FGF signaling regulator 2
novel protein
chr18_+_23949847 6.58 ENST00000588004.1
laminin subunit alpha 3
chr12_-_123268077 6.56 ENST00000542174.5
cyclin dependent kinase 2 associated protein 1
chr15_-_64162965 6.50 ENST00000300026.4
ENST00000681397.1
ENST00000681658.1
peptidylprolyl isomerase B
chr11_+_68684534 6.46 ENST00000265643.4
galanin and GMAP prepropeptide
chr10_+_74151232 6.36 ENST00000478611.2
ENST00000673352.1
adenosine kinase
chr6_+_35468393 6.34 ENST00000322203.7
ribosomal protein L10a
chr17_+_32350132 6.26 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 32.0 GO:0009216 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
6.5 26.2 GO:1903976 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976)
5.9 17.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
5.8 23.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
5.2 47.1 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
4.9 14.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
4.7 23.4 GO:0006177 GMP biosynthetic process(GO:0006177)
4.4 13.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
4.4 43.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
4.2 12.6 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
4.1 24.9 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
3.9 19.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
3.7 14.9 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
3.6 25.3 GO:0030421 defecation(GO:0030421)
3.5 17.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
3.5 41.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
3.3 26.7 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
3.3 42.5 GO:0043248 proteasome assembly(GO:0043248)
3.2 9.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
3.2 12.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
3.2 41.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
3.0 12.0 GO:0032597 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
3.0 8.9 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
2.8 22.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.7 8.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
2.6 34.3 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
2.6 13.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.5 7.6 GO:1903826 arginine transmembrane transport(GO:1903826)
2.4 16.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.3 23.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
2.3 9.4 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
2.3 27.5 GO:0046689 response to mercury ion(GO:0046689)
2.2 6.5 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
2.1 21.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
2.0 10.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
2.0 8.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
2.0 7.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.9 5.7 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
1.8 22.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.8 5.4 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
1.8 5.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.7 6.9 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
1.7 8.6 GO:0005997 xylulose metabolic process(GO:0005997)
1.7 5.1 GO:0006059 hexitol metabolic process(GO:0006059)
1.7 5.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.7 8.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.7 11.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
1.7 11.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.7 5.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
1.6 6.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
1.6 8.0 GO:0070269 pyroptosis(GO:0070269)
1.6 3.1 GO:0006404 RNA import into nucleus(GO:0006404)
1.5 27.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5 16.7 GO:0007144 female meiosis I(GO:0007144)
1.5 7.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.5 5.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
1.5 20.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
1.5 5.8 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.4 9.8 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.4 14.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.4 9.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.4 17.6 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
1.3 14.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
1.3 4.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
1.3 60.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
1.3 8.9 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.2 5.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.2 3.7 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
1.2 4.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.2 18.9 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
1.1 5.7 GO:0010193 response to ozone(GO:0010193)
1.1 6.9 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
1.1 10.2 GO:0009249 protein lipoylation(GO:0009249)
1.1 19.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.1 14.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.1 3.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) negative regulation of DNA damage checkpoint(GO:2000002)
1.1 15.6 GO:0006089 lactate metabolic process(GO:0006089)
1.1 4.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
1.1 5.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.0 7.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
1.0 6.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.0 3.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
1.0 12.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.0 2.9 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
1.0 3.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.9 3.8 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.9 9.4 GO:0005984 disaccharide metabolic process(GO:0005984)
0.9 5.6 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.9 3.7 GO:0006550 isoleucine catabolic process(GO:0006550)
0.9 6.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.9 11.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.9 4.4 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.9 8.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.9 27.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.9 3.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.9 7.8 GO:1902661 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.9 5.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.8 9.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.8 3.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.8 12.2 GO:0070986 left/right axis specification(GO:0070986)
0.8 27.3 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.8 2.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.8 3.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.8 4.6 GO:0001878 response to yeast(GO:0001878)
0.8 4.6 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.8 6.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.8 6.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.8 2.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.7 3.7 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.7 7.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 5.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.7 15.1 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.7 4.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.7 3.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.7 3.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.7 2.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.7 2.7 GO:0061086 regulation of mRNA export from nucleus(GO:0010793) negative regulation of histone H3-K27 methylation(GO:0061086)
0.7 8.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.6 8.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.6 13.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.6 17.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 8.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.6 54.8 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.6 9.4 GO:0045116 protein neddylation(GO:0045116)
0.6 24.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.6 4.9 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.6 3.7 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.6 9.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 23.9 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.6 2.9 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.6 4.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.6 12.0 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.6 1.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.6 8.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 1.7 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.5 7.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.5 2.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.5 9.2 GO:0007172 signal complex assembly(GO:0007172)
0.5 5.3 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.5 15.0 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.5 17.0 GO:0046655 folic acid metabolic process(GO:0046655)
0.5 3.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.5 22.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.5 4.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.5 3.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 10.6 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.5 0.5 GO:0090274 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.5 1.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 3.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.4 0.4 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.4 7.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.4 5.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 7.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 9.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.4 2.8 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.4 28.3 GO:0006953 acute-phase response(GO:0006953)
0.4 1.6 GO:1901143 insulin catabolic process(GO:1901143)
0.4 4.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 12.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.4 2.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 8.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 1.5 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.4 12.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 3.0 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.4 3.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 2.8 GO:0070475 rRNA base methylation(GO:0070475)
0.3 5.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 10.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.3 4.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 3.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 7.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 3.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 4.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.3 4.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 6.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.3 2.2 GO:0008050 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.3 14.3 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.3 1.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 12.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 1.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 4.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 2.3 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.3 2.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 4.4 GO:0008228 opsonization(GO:0008228)
0.3 1.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 3.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.3 4.8 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 12.1 GO:0035329 hippo signaling(GO:0035329)
0.3 7.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 12.8 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.3 11.4 GO:0006739 NADP metabolic process(GO:0006739)
0.2 0.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 2.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 1.2 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.2 3.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 3.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 2.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 21.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.2 0.4 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.2 2.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 2.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 1.3 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.2 12.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 3.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 1.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 2.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.8 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.2 9.0 GO:0006458 'de novo' protein folding(GO:0006458)
0.2 5.2 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.2 4.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 9.1 GO:0043486 histone exchange(GO:0043486)
0.2 0.9 GO:0040031 snRNA modification(GO:0040031)
0.2 0.6 GO:0044805 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.2 0.7 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2 4.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2 21.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 4.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 8.3 GO:0010470 regulation of gastrulation(GO:0010470)
0.2 4.7 GO:0030252 growth hormone secretion(GO:0030252)
0.2 2.8 GO:0006012 galactose metabolic process(GO:0006012)
0.2 15.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 2.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.2 2.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 8.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.2 1.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 8.5 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.6 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 10.9 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.1 6.8 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.6 GO:0051697 protein delipidation(GO:0051697)
0.1 1.7 GO:0034114 regulation of heterotypic cell-cell adhesion(GO:0034114)
0.1 3.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 1.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 8.8 GO:0000045 autophagosome assembly(GO:0000045)
0.1 1.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.9 GO:0001824 blastocyst development(GO:0001824)
0.1 1.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 8.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.4 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.1 0.6 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.6 GO:0061042 vascular wound healing(GO:0061042)
0.1 3.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 20.9 GO:0007051 spindle organization(GO:0007051)
0.1 6.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.6 GO:0015808 L-alanine transport(GO:0015808)
0.1 3.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 11.4 GO:0006338 chromatin remodeling(GO:0006338)
0.1 3.9 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.1 6.0 GO:0007098 centrosome cycle(GO:0007098)
0.1 1.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 2.6 GO:0031648 protein destabilization(GO:0031648)
0.1 2.0 GO:0000154 rRNA modification(GO:0000154)
0.1 1.6 GO:0006853 carnitine shuttle(GO:0006853)
0.1 2.9 GO:0033198 response to ATP(GO:0033198)
0.1 1.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.7 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 3.6 GO:0000266 mitochondrial fission(GO:0000266)
0.1 3.3 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.6 GO:0007379 segment specification(GO:0007379)
0.1 3.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 4.8 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.1 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 1.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 6.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 2.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 0.9 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 3.6 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.5 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 3.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 1.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 12.9 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.8 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.2 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.6 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 2.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 2.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 7.1 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.5 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 3.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 2.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 1.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 2.5 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 1.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.3 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of cytokine secretion involved in immune response(GO:0002740) interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.7 GO:0008306 associative learning(GO:0008306)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 33.3 GO:0008537 proteasome activator complex(GO:0008537)
4.2 12.6 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
4.0 16.2 GO:0071942 XPC complex(GO:0071942)
3.7 11.1 GO:0031262 Ndc80 complex(GO:0031262)
3.3 13.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
3.2 12.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
2.9 23.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
2.8 45.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
2.7 43.6 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
2.6 20.9 GO:0061700 GATOR2 complex(GO:0061700)
2.4 22.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
2.4 24.3 GO:0097255 R2TP complex(GO:0097255)
2.1 6.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
2.0 23.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.9 7.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.8 47.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.7 22.6 GO:0008385 IkappaB kinase complex(GO:0008385)
1.7 10.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.6 19.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.6 17.4 GO:0042587 glycogen granule(GO:0042587)
1.5 16.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.4 12.6 GO:0042382 paraspeckles(GO:0042382)
1.4 6.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.3 10.4 GO:0005827 polar microtubule(GO:0005827)
1.3 20.8 GO:0034709 methylosome(GO:0034709)
1.2 7.4 GO:0070545 PeBoW complex(GO:0070545)
1.2 12.2 GO:0061574 ASAP complex(GO:0061574)
1.2 18.8 GO:0016600 flotillin complex(GO:0016600)
1.2 3.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.2 4.6 GO:0071817 MMXD complex(GO:0071817)
1.1 22.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.1 5.6 GO:0044232 organelle membrane contact site(GO:0044232)
1.1 10.1 GO:0090543 Flemming body(GO:0090543)
1.1 3.3 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
1.1 3.2 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
1.1 27.5 GO:0002080 acrosomal membrane(GO:0002080)
1.1 3.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.0 5.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.0 11.6 GO:0071203 F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
0.9 11.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.9 6.6 GO:0005610 laminin-5 complex(GO:0005610)
0.9 14.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.9 36.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.9 9.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.8 5.7 GO:0016272 prefoldin complex(GO:0016272)
0.8 29.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.8 7.0 GO:0000439 core TFIIH complex(GO:0000439)
0.7 2.9 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.7 9.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.7 18.6 GO:0031528 microvillus membrane(GO:0031528)
0.7 37.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.6 1.9 GO:0030689 Noc complex(GO:0030689)
0.6 8.6 GO:0005686 U2 snRNP(GO:0005686)
0.6 3.6 GO:0032279 asymmetric synapse(GO:0032279)
0.6 9.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 9.0 GO:0097470 ribbon synapse(GO:0097470)
0.6 7.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 16.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.6 49.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.5 4.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 21.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 12.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.5 6.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.5 3.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.5 5.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.5 5.5 GO:0030870 Mre11 complex(GO:0030870)
0.5 5.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.5 11.2 GO:0030056 hemidesmosome(GO:0030056)
0.5 3.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 5.8 GO:0000815 ESCRT III complex(GO:0000815)
0.5 5.2 GO:0005638 lamin filament(GO:0005638)
0.5 15.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.5 3.2 GO:0032021 NELF complex(GO:0032021)
0.4 5.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.4 4.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 16.1 GO:0000791 euchromatin(GO:0000791)
0.4 5.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 4.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.4 22.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 62.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.3 17.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 12.8 GO:0042629 mast cell granule(GO:0042629)
0.3 6.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 5.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 13.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 2.0 GO:0070761 pre-snoRNP complex(GO:0070761)
0.3 44.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 1.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 11.7 GO:0008180 COP9 signalosome(GO:0008180)
0.3 8.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.3 0.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 1.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 7.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 9.0 GO:0051233 spindle midzone(GO:0051233)
0.3 0.8 GO:0042555 MCM complex(GO:0042555)
0.3 2.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 1.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 7.5 GO:0032420 stereocilium(GO:0032420)
0.2 4.1 GO:0035861 site of double-strand break(GO:0035861)
0.2 11.6 GO:0031519 PcG protein complex(GO:0031519)
0.2 9.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 20.9 GO:0042641 actomyosin(GO:0042641)
0.2 4.4 GO:0071437 invadopodium(GO:0071437)
0.2 2.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 11.0 GO:0005776 autophagosome(GO:0005776)
0.2 2.2 GO:0071141 SMAD protein complex(GO:0071141)
0.2 19.6 GO:0016605 PML body(GO:0016605)
0.2 3.3 GO:0030904 retromer complex(GO:0030904)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.2 5.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 6.5 GO:0005902 microvillus(GO:0005902)
0.1 14.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 5.2 GO:0016235 aggresome(GO:0016235)
0.1 2.1 GO:0005682 U5 snRNP(GO:0005682)
0.1 5.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 6.7 GO:0045178 basal part of cell(GO:0045178)
0.1 8.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 9.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.7 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 8.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 11.1 GO:0000922 spindle pole(GO:0000922)
0.1 38.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.3 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.1 7.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 30.3 GO:0016607 nuclear speck(GO:0016607)
0.1 4.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 7.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.6 GO:0000502 proteasome complex(GO:0000502)
0.0 5.7 GO:0005840 ribosome(GO:0005840)
0.0 2.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 3.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 58.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
10.9 43.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
8.0 32.0 GO:0004001 adenosine kinase activity(GO:0004001)
7.1 35.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
5.9 35.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
5.8 23.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
5.6 22.5 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
5.6 16.7 GO:0004766 spermidine synthase activity(GO:0004766)
5.1 40.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
4.8 33.3 GO:0061133 endopeptidase activator activity(GO:0061133)
4.6 18.3 GO:0031177 phosphopantetheine binding(GO:0031177)
4.2 12.6 GO:0002135 CTP binding(GO:0002135)
3.8 15.3 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.7 26.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
3.5 20.8 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
3.3 13.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
3.0 8.9 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.9 17.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.8 45.3 GO:0001054 RNA polymerase I activity(GO:0001054)
2.6 10.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
2.5 7.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
2.5 7.4 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
2.4 26.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.3 13.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
2.2 47.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
2.2 15.6 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
2.2 13.3 GO:1990226 histone methyltransferase binding(GO:1990226)
2.2 13.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
2.1 10.4 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
2.0 28.1 GO:0031386 protein tag(GO:0031386)
2.0 8.0 GO:0004335 galactokinase activity(GO:0004335)
1.9 11.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.8 11.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.8 3.7 GO:0070404 NADH binding(GO:0070404)
1.8 9.1 GO:0042296 ISG15 transferase activity(GO:0042296)
1.8 10.7 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) 5'-flap endonuclease activity(GO:0017108)
1.8 42.5 GO:0070628 proteasome binding(GO:0070628)
1.8 5.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
1.7 10.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
1.7 12.1 GO:0050815 phosphoserine binding(GO:0050815)
1.7 5.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
1.7 14.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.6 4.9 GO:0008384 IkappaB kinase activity(GO:0008384)
1.5 12.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.4 8.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.4 12.7 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.4 4.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.3 30.8 GO:0005537 mannose binding(GO:0005537)
1.3 9.4 GO:0019788 NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
1.3 10.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.3 6.5 GO:0004966 galanin receptor activity(GO:0004966)
1.3 3.9 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.3 5.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.3 8.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.2 5.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.2 5.9 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.2 7.1 GO:0003998 acylphosphatase activity(GO:0003998)
1.2 4.7 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
1.1 20.5 GO:0070513 death domain binding(GO:0070513)
1.1 19.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.1 7.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 8.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
1.0 7.0 GO:0000182 rDNA binding(GO:0000182)
1.0 4.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
1.0 9.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.0 2.9 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.0 5.7 GO:0004046 aminoacylase activity(GO:0004046)
0.9 3.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.9 3.7 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.9 25.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.9 5.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.8 17.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.8 4.0 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.8 22.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.8 3.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.8 2.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.7 3.7 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.7 3.7 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.7 8.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 11.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.7 3.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.7 5.8 GO:0015288 porin activity(GO:0015288)
0.7 5.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.7 33.3 GO:0050699 WW domain binding(GO:0050699)
0.7 6.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.7 6.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.7 13.5 GO:0048156 tau protein binding(GO:0048156)
0.7 12.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.7 5.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.7 4.6 GO:0051400 BH domain binding(GO:0051400)
0.6 3.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.6 4.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 5.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.6 4.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 2.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.6 3.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.6 1.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.6 1.7 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.5 8.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 5.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.5 1.6 GO:0031626 beta-endorphin binding(GO:0031626)
0.5 5.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.5 3.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 4.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.5 3.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 2.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.5 4.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.5 1.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 7.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.5 2.8 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.5 6.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 14.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 4.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 4.8 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.4 2.1 GO:0097016 L27 domain binding(GO:0097016)
0.4 7.3 GO:0035497 cAMP response element binding(GO:0035497)
0.4 6.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 3.9 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.4 2.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 2.2 GO:0035500 MH2 domain binding(GO:0035500)
0.4 9.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 4.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.4 2.9 GO:1990405 protein antigen binding(GO:1990405)
0.4 1.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 21.2 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.4 11.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 10.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 1.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 12.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 4.2 GO:0008494 translation activator activity(GO:0008494)
0.3 5.1 GO:0031996 thioesterase binding(GO:0031996)
0.3 4.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 1.5 GO:0016936 galactoside binding(GO:0016936)
0.3 11.0 GO:0001671 ATPase activator activity(GO:0001671)
0.3 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 8.5 GO:0017166 vinculin binding(GO:0017166)
0.3 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 1.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 22.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 47.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 26.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 30.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 10.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 4.4 GO:0097602 cullin family protein binding(GO:0097602)
0.3 34.1 GO:0051082 unfolded protein binding(GO:0051082)
0.3 27.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.3 4.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 6.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 9.3 GO:0043236 laminin binding(GO:0043236)
0.3 5.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 2.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 5.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 3.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.2 1.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 3.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 3.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 3.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.2 17.4 GO:0003684 damaged DNA binding(GO:0003684)
0.2 3.4 GO:0005522 profilin binding(GO:0005522)
0.2 1.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 4.2 GO:0008242 omega peptidase activity(GO:0008242)
0.2 9.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 0.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 7.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 3.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 72.4 GO:0045296 cadherin binding(GO:0045296)
0.2 8.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 14.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 2.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.2 2.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 5.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 3.3 GO:0050811 GABA receptor binding(GO:0050811)
0.2 3.1 GO:0000339 RNA cap binding(GO:0000339)
0.2 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.6 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 1.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 2.8 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 2.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 1.2 GO:0043274 phospholipase binding(GO:0043274)
0.1 4.0 GO:0000049 tRNA binding(GO:0000049)
0.1 1.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.4 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 18.7 GO:0008083 growth factor activity(GO:0008083)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 2.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 1.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0005549 odorant binding(GO:0005549)
0.1 2.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 5.0 GO:0019003 GDP binding(GO:0019003)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 5.5 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 0.9 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 3.6 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.9 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 5.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 30.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.4 5.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
1.3 100.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.2 59.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 22.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.7 9.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.6 36.2 PID ATR PATHWAY ATR signaling pathway
0.6 46.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.5 21.6 PID AURORA A PATHWAY Aurora A signaling
0.5 33.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.5 36.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.5 10.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 31.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.5 6.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 37.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 10.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 20.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.4 38.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 12.3 PID ALK1 PATHWAY ALK1 signaling events
0.3 17.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.3 19.6 PID AP1 PATHWAY AP-1 transcription factor network
0.3 24.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.3 7.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 12.1 PID P53 REGULATION PATHWAY p53 pathway
0.2 13.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 14.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 13.0 PID P73PATHWAY p73 transcription factor network
0.2 11.6 PID LKB1 PATHWAY LKB1 signaling events
0.2 7.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 24.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 15.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 1.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 5.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 7.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 7.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 4.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 7.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 12.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 8.6 PID E2F PATHWAY E2F transcription factor network
0.1 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 4.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 5.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 68.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
2.4 51.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
2.4 14.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
2.2 72.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
1.6 23.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.5 47.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.4 21.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.3 32.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.3 21.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.2 25.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
1.2 10.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.1 94.7 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
1.0 30.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.9 24.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.9 8.0 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.9 16.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.9 17.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.8 32.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.8 9.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.8 18.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.7 12.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7 19.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.7 5.7 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.7 6.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.7 2.7 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.7 10.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.6 16.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.6 25.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.6 14.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.6 7.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 26.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 4.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.5 19.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.5 14.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.5 10.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5 9.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.5 7.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.5 11.4 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.5 3.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.4 11.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 10.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 4.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 3.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4 11.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.4 16.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.4 12.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.4 10.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.4 6.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 7.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 7.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 28.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 4.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 11.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 11.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 4.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 5.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 3.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 8.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 37.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 13.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 3.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.3 10.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 5.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 9.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 10.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 4.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 3.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 4.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 3.1 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.2 9.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 0.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 3.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 4.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 1.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 4.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 8.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 9.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 3.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 10.3 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 8.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 7.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 5.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 18.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 3.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 16.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 11.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 7.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 5.9 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 3.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 3.7 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.1 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 4.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME TRANSLATION Genes involved in Translation
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation