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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GLI3

Z-value: 13.52

Motif logo

Transcription factors associated with GLI3

Gene Symbol Gene ID Gene Info
ENSG00000106571.15 GLI3

Activity-expression correlation:

Activity profile of GLI3 motif

Sorted Z-values of GLI3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_95317671 46.31 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chr22_-_19524400 38.79 ENST00000618236.2
claudin 5
chr8_-_27605271 35.01 ENST00000522098.1
clusterin
chr5_-_42825884 33.72 ENST00000506577.5
selenoprotein P
chr8_-_27611325 33.57 ENST00000523500.5
clusterin
chr19_+_44914702 32.81 ENST00000592885.5
ENST00000589781.1
apolipoprotein C1
chr19_-_20661563 31.11 ENST00000601440.6
ENST00000291750.6
ENST00000595094.1
zinc finger protein 626
novel transcript
chr19_-_20661507 30.38 ENST00000612591.4
ENST00000595405.1
zinc finger protein 626
chr19_+_44914588 28.69 ENST00000592535.6
apolipoprotein C1
chr12_+_78864768 28.43 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr3_-_15427497 28.42 ENST00000443029.5
ENST00000383789.9
ENST00000450816.6
ENST00000383790.8
methyltransferase like 6
chr19_-_34677157 28.21 ENST00000601241.6
secretoglobin family 2B member 2
chr12_-_44876294 27.21 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr6_-_158999748 25.68 ENST00000449822.5
radial spoke head 3
chr9_-_113340248 25.29 ENST00000341761.8
ENST00000374195.7
ENST00000374193.9
WD repeat domain 31
chr15_+_83447411 23.60 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr11_-_111913134 23.48 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr2_-_201071579 23.24 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chr18_-_77132771 23.08 ENST00000355994.7
ENST00000579129.5
myelin basic protein
chr11_-_111913195 22.84 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
crystallin alpha B
chr3_+_45026296 22.81 ENST00000296130.5
C-type lectin domain family 3 member B
chr19_+_44914833 22.29 ENST00000589078.1
ENST00000586638.5
apolipoprotein C1
chr8_-_27611424 22.08 ENST00000405140.7
clusterin
chr4_+_165378998 21.95 ENST00000402744.9
carboxypeptidase E
chr10_+_104269163 21.83 ENST00000338595.7
glutathione S-transferase omega 2
chr8_+_22059342 21.29 ENST00000415253.5
dematin actin binding protein
chr16_+_85027735 21.19 ENST00000258180.7
ENST00000538274.5
KIAA0513
chr19_-_45815228 21.05 ENST00000597055.1
radial spoke head 6 homolog A
chr1_-_11805977 20.78 ENST00000376486.3
methylenetetrahydrofolate reductase
chr17_-_10697501 20.39 ENST00000577427.1
ENST00000255390.10
synthesis of cytochrome C oxidase 1
chr3_+_10026409 20.34 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr4_+_71187269 20.28 ENST00000425175.5
ENST00000351898.10
solute carrier family 4 member 4
chr1_-_11805924 19.78 ENST00000418034.1
methylenetetrahydrofolate reductase
chr8_+_22059198 19.57 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chr1_-_11805949 19.56 ENST00000376590.9
methylenetetrahydrofolate reductase
chr19_+_44914247 19.10 ENST00000588750.5
ENST00000588802.5
apolipoprotein C1
chr12_-_6689450 19.02 ENST00000355772.8
ENST00000417772.7
ENST00000319770.7
ENST00000396801.7
zinc finger protein 384
chr16_-_800705 19.01 ENST00000248150.5
G protein subunit gamma 13
chr11_+_49027501 18.72 ENST00000622138.4
tripartite motif containing 49B
chr12_-_6689359 18.41 ENST00000683879.1
zinc finger protein 384
chr12_-_6689244 18.29 ENST00000361959.7
ENST00000436774.6
ENST00000544482.1
zinc finger protein 384
chr12_-_122266425 17.98 ENST00000643696.1
ENST00000267199.9
VPS33A core subunit of CORVET and HOPS complexes
chr2_+_17753852 17.77 ENST00000317402.11
GEN1 Holliday junction 5' flap endonuclease
chr3_-_58587033 17.75 ENST00000447756.2
family with sequence similarity 107 member A
chr6_-_109440504 17.65 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr2_+_238138661 17.42 ENST00000409223.2
kelch like family member 30
chr3_+_15427551 17.27 ENST00000396842.7
ELL associated factor 1
chrX_-_40647509 17.27 ENST00000378421.1
ENST00000378426.5
ENST00000327877.10
chromosome X open reading frame 38
chr11_+_114059755 17.16 ENST00000684295.1
zinc finger and BTB domain containing 16
chr2_+_17754116 17.01 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr3_+_52455589 16.95 ENST00000345716.9
ENST00000488380.5
ENST00000420808.2
nischarin
chr3_-_122564253 16.89 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
poly(ADP-ribose) polymerase family member 9
chr11_-_111912871 16.88 ENST00000528628.5
crystallin alpha B
chr20_+_37521206 16.87 ENST00000346199.3
ENST00000647955.1
ENST00000649451.1
ENST00000649697.1
ENST00000649309.1
neuronatin
chr19_-_45815303 16.75 ENST00000221538.8
radial spoke head 6 homolog A
chr1_+_156153568 16.68 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
semaphorin 4A
chr17_-_28951285 16.56 ENST00000577226.5
PHD finger protein 12
chr1_-_37692205 16.53 ENST00000477060.1
ENST00000491981.5
ENST00000488137.5
ENST00000619962.1
chromosome 1 open reading frame 109
chr1_+_35930712 16.40 ENST00000324350.9
argonaute RISC catalytic component 3
chr1_+_11806096 16.20 ENST00000312413.10
ENST00000346436.11
chloride voltage-gated channel 6
chr11_-_12009082 16.15 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr19_+_36973211 15.94 ENST00000586353.5
ENST00000433993.5
ENST00000592567.1
zinc finger protein 568
chr1_+_204870831 15.55 ENST00000404076.5
ENST00000539706.6
neurofascin
chr10_-_88952763 15.28 ENST00000224784.10
actin alpha 2, smooth muscle
chr10_-_27155214 15.03 ENST00000477432.1
YME1 like 1 ATPase
chr11_+_57598184 14.90 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr7_+_150801522 14.75 ENST00000461345.5
transmembrane protein 176A
chr6_-_46735351 14.68 ENST00000274793.12
phospholipase A2 group VII
chr3_-_139539679 14.62 ENST00000483943.6
ENST00000672186.1
ENST00000232219.6
ENST00000617459.4
ENST00000492918.1
retinol binding protein 1
chr3_-_47513303 14.48 ENST00000449409.5
ENST00000414236.5
ENST00000444760.5
ENST00000439305.5
elongator acetyltransferase complex subunit 6
chr21_-_32612806 14.41 ENST00000673807.1
CFAP298-TCP10L readthrough
chr6_-_166627244 14.26 ENST00000265678.9
ribosomal protein S6 kinase A2
chr8_+_22059169 14.23 ENST00000358242.5
dematin actin binding protein
chr12_-_44875647 14.20 ENST00000395487.6
neural EGFL like 2
chr4_-_175812746 14.17 ENST00000393658.6
glycoprotein M6A
chr14_-_102509713 14.13 ENST00000286918.9
ankyrin repeat domain 9
chr4_-_17810686 14.08 ENST00000382247.6
DDB1 and CUL4 associated factor 16
chr1_-_109619605 14.07 ENST00000679935.1
G protein subunit alpha transducin 2
chr19_+_43580544 13.89 ENST00000562255.5
ENST00000569031.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr11_+_114060204 13.86 ENST00000683318.1
zinc finger and BTB domain containing 16
chr9_-_120714457 13.80 ENST00000373930.4
multiple EGF like domains 9
chr19_+_35030626 13.76 ENST00000638536.1
sodium voltage-gated channel beta subunit 1
chr1_-_241357085 13.75 ENST00000366564.5
regulator of G protein signaling 7
chr17_-_6651557 13.71 ENST00000225728.8
ENST00000575197.1
mediator complex subunit 31
chr7_+_150801695 13.62 ENST00000475536.5
ENST00000468689.2
transmembrane protein 176A
chr19_+_4969105 13.61 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chr2_+_219627394 13.57 ENST00000373760.6
solute carrier family 4 member 3
chr15_+_81299416 13.53 ENST00000558332.3
interleukin 16
chr15_+_83447328 13.47 ENST00000427482.7
SH3 domain containing GRB2 like 3, endophilin A3
chr19_+_52397841 13.46 ENST00000360465.8
ENST00000391788.6
ENST00000436397.5
ENST00000391787.6
ENST00000494167.6
ENST00000493272.5
zinc finger protein 528
chr5_-_218136 13.40 ENST00000296824.4
coiled-coil domain containing 127
chr7_+_44044663 13.35 ENST00000456905.5
ENST00000440166.5
ENST00000452943.5
ENST00000448521.6
ENST00000468694.5
ENST00000494774.5
drebrin like
chr10_+_132332136 13.31 ENST00000344079.9
ENST00000625755.2
ENST00000368614.8
leucine rich repeat containing 27
chr1_+_19596960 13.26 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr10_+_27155339 13.25 ENST00000375940.9
ENST00000342386.10
microtubule associated serine/threonine kinase like
chr2_+_24793098 13.23 ENST00000473706.5
centromere protein O
chr20_-_52191697 13.18 ENST00000361387.6
ZFP64 zinc finger protein
chr9_-_92670124 13.17 ENST00000287996.8
inositol-pentakisphosphate 2-kinase
chr5_+_81301570 13.16 ENST00000407610.8
ENST00000254037.6
ENST00000380199.9
zinc finger CCHC-type containing 9
chr19_-_54222978 13.12 ENST00000245620.13
ENST00000346401.10
ENST00000445347.1
leukocyte immunoglobulin like receptor B3
chr19_+_2096937 13.07 ENST00000395296.5
IZUMO family member 4
chr6_+_28141830 13.07 ENST00000330236.7
zinc finger with KRAB and SCAN domains 8
chr6_-_29633056 13.04 ENST00000377016.8
gamma-aminobutyric acid type B receptor subunit 1
chr19_+_18097763 13.03 ENST00000262811.10
microtubule associated serine/threonine kinase 3
chr6_-_29633171 13.02 ENST00000377034.9
gamma-aminobutyric acid type B receptor subunit 1
chr17_+_44141899 13.01 ENST00000319977.8
ENST00000585683.6
homologous recombination factor with OB-fold
chr20_+_18588040 12.84 ENST00000377452.4
D-aminoacyl-tRNA deacylase 1
chr19_-_16542415 12.77 ENST00000198939.6
ENST00000546361.7
calcium homeostasis endoplasmic reticulum protein
chr11_-_12008584 12.74 ENST00000534511.5
ENST00000683431.1
dickkopf WNT signaling pathway inhibitor 3
chr2_-_136118142 12.68 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr5_+_140664896 12.64 ENST00000358337.10
WD repeat domain 55
chr19_+_37469337 12.52 ENST00000330173.6
zinc finger protein 570
chr6_-_28399731 12.50 ENST00000396827.3
ENST00000361028.5
ENST00000684592.1
zinc finger and SCAN domain containing 12
chr6_+_33080445 12.45 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr11_-_71928624 12.43 ENST00000533047.5
ENST00000529844.5
novel protein similar to transient receptor potential cation channel, subfamily C, member 2 TRPC2
chr2_+_219514477 12.33 ENST00000347842.8
ENST00000358078.5
acid sensing ion channel subunit family member 4
chr17_+_28357638 12.31 ENST00000292114.8
ENST00000591482.1
transmembrane protein 199
novel transcript readthrough between TMEM199 and SARM1
chr14_-_21023318 12.28 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG family member 2
chr11_+_45847406 12.27 ENST00000443527.6
ENST00000616623.4
ENST00000616080.2
cryptochrome circadian regulator 2
chr8_-_81112055 12.26 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chrX_-_108736556 12.26 ENST00000372129.4
insulin receptor substrate 4
chr1_-_20508095 12.20 ENST00000264198.5
mitochondrial E3 ubiquitin protein ligase 1
chr1_-_241357225 12.20 ENST00000366565.5
regulator of G protein signaling 7
chr15_+_85380625 12.19 ENST00000560302.5
A-kinase anchoring protein 13
chr11_+_123430259 12.09 ENST00000533341.3
ENST00000635736.2
GRAM domain containing 1B
chr19_+_2096873 12.01 ENST00000395307.6
ENST00000395301.8
ENST00000620263.4
IZUMO family member 4
chr18_+_12093839 11.98 ENST00000587848.3
ankyrin repeat domain 62
chr2_-_27628975 11.95 ENST00000324364.4
coiled-coil domain containing 121
chr7_-_108526061 11.94 ENST00000426128.6
ENST00000427008.1
ENST00000257694.13
ENST00000422087.5
ENST00000453144.5
ENST00000436062.5
patatin like phospholipase domain containing 8
chr1_+_8945858 11.92 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr9_+_87498491 11.89 ENST00000622514.4
death associated protein kinase 1
chr7_-_4883683 11.89 ENST00000399583.4
Rap associating with DIL domain
chr16_+_85027761 11.79 ENST00000683363.1
KIAA0513
chr14_+_75278820 11.79 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr4_+_71187258 11.75 ENST00000264485.11
solute carrier family 4 member 4
chr7_-_945799 11.73 ENST00000611167.4
ArfGAP with dual PH domains 1
chr9_+_78236037 11.71 ENST00000424347.6
ENST00000645398.1
ENST00000643347.1
ENST00000643273.2
ENST00000647199.1
ENST00000643847.1
ENST00000643499.1
ENST00000415759.6
ENST00000376597.9
ENST00000277082.9
ENST00000642669.1
ENST00000642214.1
ENST00000644208.1
ENST00000376598.3
centrosomal protein 78
chr9_-_98708856 11.69 ENST00000259455.4
gamma-aminobutyric acid type B receptor subunit 2
chr14_-_21023954 11.59 ENST00000554094.5
NDRG family member 2
chr8_+_1973668 11.58 ENST00000320248.4
kelch repeat and BTB domain containing 11
chr19_+_58451607 11.56 ENST00000545523.5
ENST00000599194.5
ENST00000336614.9
ENST00000598244.5
ENST00000599193.5
ENST00000594214.1
zinc finger protein 324B
chr7_+_29806483 11.54 ENST00000409123.5
ENST00000242140.9
WAS/WASL interacting protein family member 3
chr8_-_144475808 11.52 ENST00000377317.5
forkhead box H1
chrY_+_14056226 11.51 ENST00000250823.5
variable charge Y-linked 1B
chr1_+_2050387 11.51 ENST00000378567.8
protein kinase C zeta
chr11_-_61917490 11.47 ENST00000394836.7
RAB3A interacting protein like 1
chr16_+_84175933 11.46 ENST00000569735.1
dynein axonemal assembly factor 1
chr2_-_241102192 11.46 ENST00000434791.1
ENST00000401626.6
ENST00000391980.7
ENST00000439144.5
ENST00000614476.4
ENST00000406593.1
ENST00000495694.5
ENST00000407095.3
mitochondrial transcription termination factor 4
chr14_-_105601728 11.45 ENST00000641420.1
ENST00000390541.2
immunoglobulin heavy constant epsilon
chr19_+_2096960 11.45 ENST00000588003.5
IZUMO family member 4
chr12_-_112382363 11.40 ENST00000682272.1
ENST00000377560.9
HECT domain E3 ubiquitin protein ligase 4
chr20_+_59933761 11.40 ENST00000358293.7
family with sequence similarity 217 member B
chr19_+_49496424 11.36 ENST00000596873.1
ENST00000594493.1
ENST00000270625.7
ENST00000599561.1
ribosomal protein S11
chr14_+_92923143 11.33 ENST00000216492.10
ENST00000334654.4
chromogranin A
chr1_-_161021096 11.33 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr16_-_75536071 11.32 ENST00000336257.8
carbohydrate sulfotransferase 5
chr17_+_44142015 11.31 ENST00000245382.6
homologous recombination factor with OB-fold
chr1_+_228165794 11.22 ENST00000366711.4
iron-sulfur cluster assembly factor IBA57
chr16_+_56191476 11.18 ENST00000262493.12
G protein subunit alpha o1
chr12_+_119593758 11.14 ENST00000426426.3
transmembrane protein 233
chr19_-_19643547 11.10 ENST00000587238.5
GEM interacting protein
chr4_-_87220491 11.08 ENST00000425278.6
ENST00000498875.6
kelch like family member 8
chr19_+_35138778 11.02 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr14_-_20436161 10.99 ENST00000636854.3
kelch like family member 33
chr6_-_159000174 10.98 ENST00000367069.7
radial spoke head 3
chr21_-_26843063 10.91 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_+_8580387 10.90 ENST00000382487.5
G protein-coupled receptor 78
chr9_-_83956677 10.84 ENST00000376344.8
chromosome 9 open reading frame 64
chr12_-_10390023 10.82 ENST00000240618.11
killer cell lectin like receptor K1
chr4_-_87220603 10.81 ENST00000273963.10
kelch like family member 8
chr3_-_15099122 10.79 ENST00000507357.1
ENST00000449050.5
ENST00000253699.7
ENST00000476527.6
rabenosyn, RAB effector
chr2_-_200864561 10.78 ENST00000434813.3
CDC like kinase 1
chr19_+_17527250 10.75 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
niban apoptosis regulator 3
chr15_+_59206832 10.73 ENST00000307144.6
lactate dehydrogenase A like 6B
chr1_-_241357171 10.69 ENST00000440928.6
regulator of G protein signaling 7
chr13_-_113410938 10.65 ENST00000682618.1
ADP-ribosylhydrolase like 1
chr6_-_46735693 10.63 ENST00000537365.1
phospholipase A2 group VII
chr2_+_219627622 10.57 ENST00000358055.8
solute carrier family 4 member 3
chr8_+_132919403 10.49 ENST00000519178.5
thyroglobulin
chr9_-_129110649 10.47 ENST00000455830.2
ENST00000455396.2
ENST00000393384.3
ENST00000681627.1
ENST00000681325.1
ENST00000680117.1
ENST00000681725.1
ENST00000318080.7
carnitine O-acetyltransferase
chr14_-_100587404 10.45 ENST00000554140.2
brain enriched guanylate kinase associated
chrX_-_52707161 10.35 ENST00000336777.9
ENST00000337502.5
SSX family member 2
chr19_+_35030438 10.34 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr19_-_42427379 10.32 ENST00000244289.9
lipase E, hormone sensitive type
chr5_-_112419251 10.30 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr7_-_954666 10.22 ENST00000265846.10
ENST00000649206.1
ArfGAP with dual PH domains 1
chr19_+_35030711 10.19 ENST00000595652.5
sodium voltage-gated channel beta subunit 1
chr5_+_69415065 10.19 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVEL domain containing 2
chr2_-_68467272 10.17 ENST00000377957.4
F-box protein 48
chr1_+_10430720 10.15 ENST00000602296.6
CENPS-CORT readthrough
chrX_+_44873169 10.15 ENST00000675577.1
ENST00000674867.1
ENST00000674586.1
ENST00000382899.9
ENST00000536777.6
ENST00000543216.6
ENST00000377967.9
ENST00000611820.5
lysine demethylase 6A
chr16_-_4416621 10.06 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chr21_-_26843012 10.05 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr6_+_11537738 10.03 ENST00000379426.2
transmembrane protein 170B
chr12_-_54188871 9.98 ENST00000504338.5
ENST00000514685.5
ENST00000504797.1
ENST00000513838.5
ENST00000505128.5
ENST00000337581.7
ENST00000503306.5
ENST00000243112.9
ENST00000514196.5
ENST00000682136.1
ENST00000506169.5
ENST00000507904.5
ENST00000508394.6
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr4_+_76011171 9.98 ENST00000513353.5
ENST00000341029.9
ADP-ribosyltransferase 3 (inactive)
chr4_-_5893075 9.97 ENST00000324989.12
collapsin response mediator protein 1
chr11_+_1410443 9.93 ENST00000528710.5
BR serine/threonine kinase 2
chr19_-_3868993 9.91 ENST00000674260.1
ENST00000592398.1
ENST00000439086.2
ENST00000262961.9
zinc finger RNA binding protein 2
chr11_+_68460712 9.90 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
protein phosphatase 6 regulatory subunit 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
25.7 102.9 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
18.1 90.7 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
11.6 34.8 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
10.0 60.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
9.5 28.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
7.9 55.1 GO:0070560 protein secretion by platelet(GO:0070560)
6.8 47.9 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
6.1 18.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
6.0 18.1 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
5.8 28.9 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
5.4 21.4 GO:0003095 pressure natriuresis(GO:0003095)
5.2 15.6 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
5.2 31.0 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
5.0 15.0 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
5.0 14.9 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
4.9 24.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
4.7 14.1 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
4.6 18.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
4.5 13.5 GO:0060032 notochord regression(GO:0060032)
4.4 21.9 GO:0030070 insulin processing(GO:0030070)
4.3 38.8 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
4.3 21.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
4.2 25.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
4.2 16.7 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
4.1 12.4 GO:0071812 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
4.1 12.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
4.1 20.4 GO:0090131 mesenchyme migration(GO:0090131)
3.8 11.3 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
3.7 11.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
3.6 10.7 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
3.4 20.5 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
3.3 10.0 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
3.3 13.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
3.3 42.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.2 9.5 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
3.1 24.5 GO:0019732 antifungal humoral response(GO:0019732)
3.0 9.0 GO:0030221 basophil differentiation(GO:0030221) positive regulation of chromatin assembly or disassembly(GO:0045799) astrocyte fate commitment(GO:0060018)
3.0 41.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
2.9 14.7 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
2.9 11.5 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
2.9 2.9 GO:0001554 luteolysis(GO:0001554)
2.8 28.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
2.8 8.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
2.7 16.4 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
2.6 5.2 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
2.5 43.0 GO:0007021 tubulin complex assembly(GO:0007021)
2.5 69.0 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
2.5 14.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
2.5 29.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
2.4 12.2 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
2.4 16.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
2.4 7.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
2.4 7.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
2.3 7.0 GO:0030573 bile acid catabolic process(GO:0030573)
2.3 25.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.3 11.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
2.3 11.4 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
2.2 6.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
2.1 10.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
2.1 6.4 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
2.1 10.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
2.0 6.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
2.0 9.9 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
2.0 7.8 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.9 3.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.9 5.7 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
1.9 15.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.9 9.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.9 7.5 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.8 5.5 GO:0046110 purine nucleobase catabolic process(GO:0006145) xanthine metabolic process(GO:0046110)
1.8 12.8 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.8 5.4 GO:0001757 somite specification(GO:0001757)
1.8 5.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.8 14.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.8 7.0 GO:0002317 plasma cell differentiation(GO:0002317)
1.7 12.2 GO:0015705 iodide transport(GO:0015705)
1.7 5.2 GO:0050748 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) negative regulation of lipoprotein metabolic process(GO:0050748)
1.7 10.4 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.7 10.3 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
1.7 3.4 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
1.7 5.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.7 11.8 GO:0001661 conditioned taste aversion(GO:0001661)
1.7 11.7 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.7 5.0 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.7 24.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.6 8.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
1.6 4.9 GO:0007525 somatic muscle development(GO:0007525)
1.6 11.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
1.6 4.8 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.6 8.0 GO:0072014 proximal tubule development(GO:0072014)
1.6 6.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.6 11.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.6 14.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.6 6.2 GO:1903633 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
1.6 6.2 GO:1904141 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.5 9.3 GO:0071896 protein localization to adherens junction(GO:0071896)
1.5 7.7 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.5 4.5 GO:0098582 innate vocalization behavior(GO:0098582)
1.5 72.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
1.5 7.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.5 13.3 GO:0007135 meiosis II(GO:0007135)
1.4 8.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.4 11.3 GO:0006477 protein sulfation(GO:0006477)
1.4 4.2 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
1.4 12.7 GO:0009249 protein lipoylation(GO:0009249)
1.4 23.9 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.4 4.2 GO:0071486 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
1.4 4.1 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.4 12.3 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
1.4 16.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
1.4 17.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.4 12.2 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
1.3 76.4 GO:0015701 bicarbonate transport(GO:0015701)
1.3 5.4 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.3 3.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.3 17.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.3 12.7 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.3 11.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
1.2 6.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.2 28.3 GO:0006895 Golgi to endosome transport(GO:0006895)
1.2 4.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.2 8.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
1.2 4.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.1 11.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.1 6.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.1 5.6 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
1.1 7.9 GO:0006701 progesterone biosynthetic process(GO:0006701)
1.1 6.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.1 2.1 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
1.1 3.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
1.1 19.0 GO:0034389 lipid particle organization(GO:0034389)
1.0 14.6 GO:0006776 vitamin A metabolic process(GO:0006776)
1.0 3.1 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.0 11.3 GO:0036158 outer dynein arm assembly(GO:0036158)
1.0 7.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.0 4.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.0 3.0 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
1.0 4.0 GO:0032571 response to vitamin K(GO:0032571) response to hydroxyisoflavone(GO:0033594)
1.0 4.0 GO:0010157 response to chlorate(GO:0010157)
1.0 12.8 GO:0006450 regulation of translational fidelity(GO:0006450)
1.0 1.0 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
1.0 2.9 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.0 13.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
1.0 32.7 GO:0015874 norepinephrine transport(GO:0015874)
1.0 8.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
1.0 1.0 GO:0042938 dipeptide transport(GO:0042938)
1.0 21.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.9 11.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.9 14.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.9 6.0 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.9 8.6 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.9 6.8 GO:0007506 gonadal mesoderm development(GO:0007506)
0.9 2.6 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.8 4.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 6.6 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8 6.5 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.8 11.4 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.8 16.9 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.8 4.8 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.8 4.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.8 6.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.8 4.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.8 5.5 GO:0080009 mRNA methylation(GO:0080009)
0.8 2.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.8 10.0 GO:0045008 depyrimidination(GO:0045008)
0.8 1.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.8 4.5 GO:0006196 AMP catabolic process(GO:0006196)
0.8 0.8 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.7 2.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.7 2.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.7 4.9 GO:0045425 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.7 8.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.7 7.6 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.7 4.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.7 6.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.7 6.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.7 4.7 GO:0097267 lipid hydroxylation(GO:0002933) omega-hydroxylase P450 pathway(GO:0097267)
0.7 16.9 GO:0042572 retinol metabolic process(GO:0042572)
0.7 6.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.7 4.7 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.7 8.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.7 5.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.7 9.9 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.7 11.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.7 36.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.7 2.0 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.6 3.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.6 5.7 GO:1902255 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.6 10.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.6 1.9 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.6 10.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 34.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.6 14.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.6 1.8 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.6 17.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.6 2.3 GO:0051697 protein delipidation(GO:0051697)
0.6 8.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.6 2.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.6 12.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.6 8.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.6 12.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.6 10.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.6 3.3 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.6 5.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.6 3.9 GO:0046618 drug export(GO:0046618)
0.6 3.3 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.6 6.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.6 2.2 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.5 4.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.5 8.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.5 3.2 GO:0035617 stress granule disassembly(GO:0035617)
0.5 9.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.5 1.0 GO:0035419 activation of MAPK activity involved in innate immune response(GO:0035419)
0.5 5.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.5 1.0 GO:0048541 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.5 8.0 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
0.5 20.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.5 2.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.5 3.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.5 12.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 9.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.5 3.3 GO:1900122 positive regulation of keratinocyte migration(GO:0051549) positive regulation of receptor binding(GO:1900122)
0.5 5.9 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.4 5.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 5.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.4 1.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.4 5.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 14.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 1.7 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.4 0.8 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4 2.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.4 1.6 GO:0070673 response to interleukin-18(GO:0070673)
0.4 3.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 15.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.4 6.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.4 2.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 5.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 8.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.4 8.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 6.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 8.7 GO:0007616 long-term memory(GO:0007616)
0.4 3.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 3.5 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.4 3.8 GO:0072540 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell lineage commitment(GO:0072540)
0.4 1.9 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.4 11.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 2.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 5.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 30.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 2.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.4 0.7 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 3.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.3 2.8 GO:0045023 G0 to G1 transition(GO:0045023)
0.3 13.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.3 5.0 GO:0045475 locomotor rhythm(GO:0045475)
0.3 15.8 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 4.9 GO:0006020 inositol metabolic process(GO:0006020)
0.3 1.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.3 2.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.3 3.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 11.3 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 3.4 GO:0035878 nail development(GO:0035878)
0.3 7.1 GO:0045109 intermediate filament organization(GO:0045109)
0.3 6.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 3.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.3 3.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 0.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 6.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 9.5 GO:0071711 basement membrane organization(GO:0071711)
0.3 5.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 4.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.3 5.9 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.3 5.5 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.2 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.3 3.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.3 7.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.3 17.2 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.3 3.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 7.3 GO:0035640 exploration behavior(GO:0035640)
0.3 7.7 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 2.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 5.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.3 2.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3 3.3 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.3 1.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.5 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 0.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 3.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.2 4.2 GO:0006833 water transport(GO:0006833)
0.2 1.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 2.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 1.7 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 2.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 1.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 2.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 4.5 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.2 1.6 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.2 7.6 GO:0035456 response to interferon-beta(GO:0035456)
0.2 6.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.2 5.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 5.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 1.5 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 2.6 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.2 5.9 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.6 GO:1900081 negative regulation of cardiac muscle adaptation(GO:0010616) regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) negative regulation of adrenergic receptor signaling pathway(GO:0071878) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 5.7 GO:0007413 axonal fasciculation(GO:0007413)
0.2 18.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.2 2.3 GO:0007512 adult heart development(GO:0007512)
0.2 0.9 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.2 2.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 13.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.2 3.7 GO:0000266 mitochondrial fission(GO:0000266)
0.2 1.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 2.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 7.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 4.8 GO:2000811 negative regulation of anoikis(GO:2000811)
0.2 109.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.2 0.9 GO:0060033 anatomical structure regression(GO:0060033)
0.1 10.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) homologous recombination-dependent replication fork processing(GO:1990426)
0.1 6.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.3 GO:0010954 positive regulation of protein processing(GO:0010954)
0.1 1.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 6.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 3.2 GO:0050909 sensory perception of taste(GO:0050909)
0.1 15.4 GO:0007286 spermatid development(GO:0007286)
0.1 2.2 GO:0046697 decidualization(GO:0046697)
0.1 2.9 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 8.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 9.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.6 GO:0015074 DNA integration(GO:0015074)
0.1 2.4 GO:0045821 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 5.6 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.1 5.2 GO:0007631 feeding behavior(GO:0007631)
0.1 3.7 GO:0014047 glutamate secretion(GO:0014047)
0.1 1.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.8 GO:0097502 mannosylation(GO:0097502)
0.1 1.4 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 1.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 3.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 8.6 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 1.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.9 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) cell differentiation involved in salivary gland development(GO:0060689) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) positive regulation of gastrulation(GO:2000543)
0.1 0.5 GO:0038007 anterior/posterior axon guidance(GO:0033564) netrin-activated signaling pathway(GO:0038007)
0.1 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.6 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.1 3.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 1.9 GO:0006040 amino sugar metabolic process(GO:0006040)
0.1 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 5.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 6.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 0.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 2.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 1.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 2.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 2.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.6 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 5.1 GO:0007601 visual perception(GO:0007601)
0.0 1.0 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 1.0 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 1.2 GO:0003279 cardiac septum development(GO:0003279)
0.0 0.8 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 1.0 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 37.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
6.9 111.0 GO:0042583 chromaffin granule(GO:0042583)
5.1 10.2 GO:0061689 tricellular tight junction(GO:0061689)
5.1 15.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
4.6 22.8 GO:0001652 granular component(GO:0001652)
4.4 70.0 GO:0097512 cardiac myofibril(GO:0097512)
4.1 102.8 GO:0042627 chylomicron(GO:0042627)
4.0 20.1 GO:0070847 core mediator complex(GO:0070847)
3.7 44.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
3.6 21.4 GO:0033269 internode region of axon(GO:0033269)
3.2 9.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
3.1 15.5 GO:0097454 Schwann cell microvillus(GO:0097454)
3.0 8.9 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
3.0 17.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.9 71.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
2.7 8.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.5 20.4 GO:0033648 host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655)
2.3 11.5 GO:0032444 activin responsive factor complex(GO:0032444)
2.2 8.8 GO:0070876 SOSS complex(GO:0070876)
2.1 8.5 GO:0070695 FHF complex(GO:0070695)
2.1 14.7 GO:0036157 outer dynein arm(GO:0036157)
2.0 10.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
2.0 18.0 GO:0030897 HOPS complex(GO:0030897)
2.0 29.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
2.0 11.7 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.8 29.2 GO:0031089 platelet dense granule lumen(GO:0031089)
1.8 15.9 GO:0044294 dendritic growth cone(GO:0044294)
1.7 5.1 GO:0032426 stereocilium tip(GO:0032426)
1.6 16.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.6 7.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.6 7.8 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.5 47.9 GO:0034706 sodium channel complex(GO:0034706)
1.5 6.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.5 7.7 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
1.5 11.8 GO:0035976 AP1 complex(GO:0035976)
1.4 11.5 GO:0045179 apical cortex(GO:0045179)
1.4 4.1 GO:0016938 kinesin I complex(GO:0016938)
1.3 4.0 GO:0035189 Rb-E2F complex(GO:0035189)
1.3 9.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.3 14.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.3 89.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.3 7.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
1.2 11.2 GO:0071953 elastic fiber(GO:0071953)
1.2 8.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.2 40.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.2 21.0 GO:0043194 axon initial segment(GO:0043194)
1.1 20.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.1 3.4 GO:0031933 telomeric heterochromatin(GO:0031933)
1.1 5.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.0 6.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.0 6.2 GO:0031501 mannosyltransferase complex(GO:0031501)
1.0 3.0 GO:0072536 interleukin-23 receptor complex(GO:0072536)
1.0 3.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.9 8.3 GO:0001520 outer dense fiber(GO:0001520)
0.9 10.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.9 15.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.9 6.2 GO:0072687 meiotic spindle(GO:0072687)
0.9 11.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.9 4.3 GO:0044308 axonal spine(GO:0044308)
0.9 34.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.8 4.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.8 14.2 GO:0044295 axonal growth cone(GO:0044295)
0.8 16.6 GO:0016580 Sin3 complex(GO:0016580)
0.8 12.3 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.8 9.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.8 6.0 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.7 5.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.7 5.9 GO:0005593 FACIT collagen trimer(GO:0005593)
0.7 5.9 GO:0072487 MSL complex(GO:0072487)
0.7 2.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.7 8.7 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.6 6.4 GO:0000800 lateral element(GO:0000800)
0.6 1.9 GO:0043293 apoptosome(GO:0043293)
0.6 8.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.6 11.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 6.5 GO:0060171 stereocilium membrane(GO:0060171)
0.6 18.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.6 18.3 GO:0035869 ciliary transition zone(GO:0035869)
0.5 3.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.5 1.5 GO:0033270 paranode region of axon(GO:0033270)
0.5 9.1 GO:0031045 dense core granule(GO:0031045)
0.5 14.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.5 3.5 GO:1990635 proximal dendrite(GO:1990635)
0.5 6.5 GO:0035253 ciliary rootlet(GO:0035253)
0.5 7.9 GO:0035102 PRC1 complex(GO:0035102)
0.5 3.4 GO:0044327 dendritic spine head(GO:0044327)
0.5 3.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 12.5 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.5 24.2 GO:0045171 intercellular bridge(GO:0045171)
0.5 16.3 GO:0042629 mast cell granule(GO:0042629)
0.4 12.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.4 12.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 15.4 GO:0097546 ciliary base(GO:0097546)
0.4 5.9 GO:0000145 exocyst(GO:0000145)
0.4 23.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 11.5 GO:0042101 T cell receptor complex(GO:0042101)
0.4 26.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.4 6.2 GO:0031201 SNARE complex(GO:0031201)
0.3 13.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 3.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 4.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 2.2 GO:0036021 endolysosome lumen(GO:0036021)
0.3 12.5 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.3 7.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 1.7 GO:0000322 storage vacuole(GO:0000322)
0.3 7.2 GO:1904115 axon cytoplasm(GO:1904115)
0.3 18.3 GO:0036064 ciliary basal body(GO:0036064)
0.3 13.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 11.1 GO:0030673 axolemma(GO:0030673)
0.3 13.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 6.2 GO:0032982 myosin filament(GO:0032982)
0.2 0.7 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.2 4.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 1.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 3.8 GO:0097225 sperm midpiece(GO:0097225)
0.2 0.7 GO:0034657 GID complex(GO:0034657)
0.2 2.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 7.5 GO:0071564 npBAF complex(GO:0071564)
0.2 7.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 0.8 GO:0035841 new growing cell tip(GO:0035841)
0.2 2.5 GO:0031209 SCAR complex(GO:0031209)
0.2 4.4 GO:0001772 immunological synapse(GO:0001772)
0.2 15.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 6.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 53.3 GO:0001726 ruffle(GO:0001726)
0.2 18.2 GO:0030426 growth cone(GO:0030426)
0.2 3.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 45.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 3.9 GO:0002080 acrosomal membrane(GO:0002080)
0.2 4.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 21.6 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 20.3 GO:0016605 PML body(GO:0016605)
0.1 0.7 GO:0016342 catenin complex(GO:0016342)
0.1 10.5 GO:0005811 lipid particle(GO:0005811)
0.1 3.8 GO:0035580 specific granule lumen(GO:0035580)
0.1 3.1 GO:0016592 mediator complex(GO:0016592)
0.1 126.3 GO:0005615 extracellular space(GO:0005615)
0.1 5.8 GO:0034704 calcium channel complex(GO:0034704)
0.1 3.5 GO:0016235 aggresome(GO:0016235)
0.1 3.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.6 GO:0043235 receptor complex(GO:0043235)
0.1 9.6 GO:0005604 basement membrane(GO:0005604)
0.1 7.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 4.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 7.2 GO:0035579 specific granule membrane(GO:0035579)
0.1 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 18.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 6.5 GO:0030424 axon(GO:0030424)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 8.6 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 6.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 6.5 GO:0005769 early endosome(GO:0005769)
0.0 14.4 GO:0045202 synapse(GO:0045202)
0.0 1.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 6.5 GO:0045177 apical part of cell(GO:0045177)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)
0.0 1.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 11.2 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.4 102.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
10.0 60.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
9.4 37.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
7.7 38.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
5.7 28.4 GO:0030348 syntaxin-3 binding(GO:0030348)
5.0 34.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
4.7 14.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
4.4 21.8 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
4.3 55.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
4.2 16.8 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
3.9 90.7 GO:0051787 misfolded protein binding(GO:0051787)
3.9 35.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
3.6 21.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
3.4 10.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
3.4 16.9 GO:0070573 metallodipeptidase activity(GO:0070573)
3.2 9.5 GO:0032093 SAM domain binding(GO:0032093)
3.1 9.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
3.0 23.8 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
3.0 11.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.9 8.7 GO:0070538 oleic acid binding(GO:0070538)
2.8 33.7 GO:0008430 selenium binding(GO:0008430)
2.8 56.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
2.7 16.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
2.7 13.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
2.7 10.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
2.6 31.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.5 10.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
2.4 22.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
2.4 7.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
2.3 18.2 GO:0005000 vasopressin receptor activity(GO:0005000)
2.1 8.6 GO:0005497 androgen binding(GO:0005497)
2.1 12.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
2.1 62.4 GO:0005212 structural constituent of eye lens(GO:0005212)
2.1 6.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
2.1 6.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
2.0 28.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
2.0 8.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
2.0 8.0 GO:0035939 microsatellite binding(GO:0035939)
1.9 5.8 GO:0004556 alpha-amylase activity(GO:0004556)
1.9 5.8 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
1.9 5.7 GO:0005055 laminin receptor activity(GO:0005055)
1.9 15.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.9 9.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.8 5.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.8 9.0 GO:0034190 apolipoprotein receptor binding(GO:0034190) apolipoprotein A-I receptor binding(GO:0034191)
1.8 21.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.8 24.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.7 28.6 GO:0009881 photoreceptor activity(GO:0009881)
1.6 14.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.6 11.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.6 25.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
1.6 6.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
1.6 26.6 GO:0042043 neurexin family protein binding(GO:0042043)
1.6 6.2 GO:0004341 gluconolactonase activity(GO:0004341)
1.5 10.7 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
1.5 7.6 GO:0004803 transposase activity(GO:0004803)
1.5 6.0 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
1.5 10.5 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
1.5 13.3 GO:0016015 morphogen activity(GO:0016015)
1.4 10.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.4 10.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
1.4 5.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.4 5.6 GO:0097108 hedgehog family protein binding(GO:0097108)
1.4 8.4 GO:0017098 sulfonylurea receptor binding(GO:0017098)
1.4 4.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.4 8.4 GO:0061665 SUMO ligase activity(GO:0061665)
1.4 16.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
1.4 5.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.3 4.0 GO:0033142 progesterone receptor binding(GO:0033142)
1.3 17.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
1.3 5.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.3 5.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.2 6.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.2 13.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.2 17.2 GO:0045504 dynein heavy chain binding(GO:0045504)
1.2 2.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.2 2.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.2 21.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.1 8.0 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
1.1 15.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.1 14.6 GO:0019841 retinol binding(GO:0019841)
1.1 5.6 GO:0004882 androgen receptor activity(GO:0004882)
1.1 7.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.1 66.7 GO:0030507 spectrin binding(GO:0030507)
1.1 8.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.1 22.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.0 5.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.0 6.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
1.0 3.0 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
1.0 4.0 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
1.0 14.7 GO:0019789 SUMO transferase activity(GO:0019789)
1.0 3.9 GO:0015307 drug:proton antiporter activity(GO:0015307)
1.0 8.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.0 8.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.9 27.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.9 5.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9 16.7 GO:0038191 neuropilin binding(GO:0038191)
0.9 11.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.9 12.0 GO:0045159 myosin II binding(GO:0045159)
0.9 14.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.9 18.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.8 8.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.8 2.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.8 6.6 GO:0043426 MRF binding(GO:0043426)
0.8 1.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.8 4.0 GO:0004905 type I interferon receptor activity(GO:0004905)
0.8 11.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.8 2.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.8 6.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.8 6.2 GO:1990405 protein antigen binding(GO:1990405)
0.8 12.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.8 5.3 GO:0034235 GPI anchor binding(GO:0034235)
0.7 3.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.7 8.6 GO:0038132 neuregulin binding(GO:0038132)
0.7 2.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.7 6.3 GO:0004875 complement receptor activity(GO:0004875)
0.7 11.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.7 18.8 GO:0035198 miRNA binding(GO:0035198)
0.7 4.8 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.7 2.7 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.7 13.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.7 16.9 GO:0070403 NAD+ binding(GO:0070403)
0.6 3.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.6 14.6 GO:0043274 phospholipase binding(GO:0043274)
0.6 13.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.6 9.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.6 5.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 11.5 GO:0031005 filamin binding(GO:0031005)
0.6 20.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 2.4 GO:0019862 IgA binding(GO:0019862)
0.6 3.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.6 4.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 2.3 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.6 9.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.6 9.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.6 2.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.6 18.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.6 9.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 3.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.5 7.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 15.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 9.1 GO:0016805 dipeptidase activity(GO:0016805)
0.5 5.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.5 3.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 3.1 GO:0030172 troponin C binding(GO:0030172)
0.5 4.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 20.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.5 3.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 59.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 2.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.5 1.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.5 7.9 GO:0019864 IgG binding(GO:0019864)
0.5 9.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.5 11.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 31.8 GO:0019843 rRNA binding(GO:0019843)
0.4 8.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 3.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.4 2.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.4 12.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.4 6.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 8.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.4 5.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 4.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 24.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 2.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.4 2.0 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4 2.4 GO:0039552 RIG-I binding(GO:0039552)
0.4 4.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 12.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 2.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.4 1.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.4 6.2 GO:0031432 titin binding(GO:0031432)
0.4 2.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 4.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 6.8 GO:0070330 aromatase activity(GO:0070330)
0.4 8.9 GO:0030371 translation repressor activity(GO:0030371)
0.4 8.5 GO:0070840 dynein complex binding(GO:0070840)
0.4 8.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.3 15.7 GO:0005272 sodium channel activity(GO:0005272)
0.3 1.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 6.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 3.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 11.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 16.3 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.3 20.2 GO:0070412 R-SMAD binding(GO:0070412)
0.3 4.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 2.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 3.4 GO:1990239 steroid hormone binding(GO:1990239)
0.3 5.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 8.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 51.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.3 5.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 7.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 19.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 25.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 5.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 8.8 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.3 7.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 4.2 GO:0015250 water channel activity(GO:0015250)
0.3 7.8 GO:0005521 lamin binding(GO:0005521)
0.3 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 2.9 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3 3.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 7.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 1.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.2 2.2 GO:0048495 Roundabout binding(GO:0048495)
0.2 25.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 8.3 GO:0030332 cyclin binding(GO:0030332)
0.2 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 25.3 GO:0005262 calcium channel activity(GO:0005262)
0.2 29.4 GO:0005179 hormone activity(GO:0005179)
0.2 2.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 6.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 18.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 3.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 0.8 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 6.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 4.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 5.6 GO:0005109 frizzled binding(GO:0005109)
0.2 1.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 1.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.2 7.6 GO:0015026 coreceptor activity(GO:0015026)
0.2 18.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.2 4.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 1.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 0.7 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 6.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 3.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 1.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.2 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.2 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.2 5.6 GO:0008066 glutamate receptor activity(GO:0008066)
0.1 0.7 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 5.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 6.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 9.0 GO:0070888 E-box binding(GO:0070888)
0.1 33.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 5.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0043199 sulfate binding(GO:0043199)
0.1 1.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 7.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 4.6 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 1.7 GO:0032183 SUMO binding(GO:0032183)
0.1 3.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 4.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 4.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 7.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 17.9 GO:0005096 GTPase activator activity(GO:0005096)
0.1 17.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 7.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 10.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 3.5 GO:0017022 myosin binding(GO:0017022)
0.1 3.0 GO:0002039 p53 binding(GO:0002039)
0.0 4.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 11.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 7.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.5 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 29.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.1 54.7 PID BARD1 PATHWAY BARD1 signaling events
0.8 110.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.7 38.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.7 8.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.7 30.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.7 10.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.7 7.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 27.0 PID RAS PATHWAY Regulation of Ras family activation
0.6 27.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.6 6.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.6 14.1 PID CONE PATHWAY Visual signal transduction: Cones
0.6 14.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.6 22.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.5 35.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.5 22.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.5 10.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.5 24.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.5 8.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4 16.8 PID ARF6 PATHWAY Arf6 signaling events
0.4 6.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 14.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.4 4.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.4 5.5 PID IL5 PATHWAY IL5-mediated signaling events
0.4 19.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 8.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 6.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 5.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 17.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 7.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 7.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 11.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 5.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 7.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 5.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.3 8.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 4.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 11.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 9.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 9.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 3.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 3.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 3.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 9.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 6.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 5.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.2 15.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 2.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 7.1 PID SHP2 PATHWAY SHP2 signaling
0.2 4.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 36.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 11.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 6.7 PID FGF PATHWAY FGF signaling pathway
0.1 6.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 40.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.9 PID ENDOTHELIN PATHWAY Endothelins
0.1 5.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.9 ST GA13 PATHWAY G alpha 13 Pathway
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 1.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 7.1 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
2.7 67.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
2.2 43.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.1 12.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.0 4.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.4 62.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.3 52.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.3 21.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.3 35.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
1.3 28.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.2 24.4 REACTOME DEFENSINS Genes involved in Defensins
1.1 16.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.0 25.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
1.0 6.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
1.0 18.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.9 17.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.9 70.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.9 34.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 10.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.9 24.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 14.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 28.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.6 14.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 17.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6 12.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6 8.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.6 13.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5 6.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.5 11.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.5 6.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 10.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5 32.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.5 8.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 11.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 45.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.5 6.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.5 4.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.5 1.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 7.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 7.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 25.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.4 15.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.4 7.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 53.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4 15.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.4 9.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 8.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.4 6.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 7.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 4.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.4 10.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 4.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 66.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.3 4.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 4.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 11.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 4.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 22.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 7.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 11.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 3.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 6.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 13.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 8.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 8.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.3 7.2 REACTOME KINESINS Genes involved in Kinesins
0.3 6.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 35.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 9.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 23.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 14.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 6.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 2.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 2.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 4.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 7.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 5.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 5.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 4.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 2.0 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.2 7.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 5.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 13.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 2.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 15.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 8.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 14.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 7.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 7.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 27.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 4.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 5.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 3.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules