Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for GLIS1

Z-value: 0.78

Motif logo

logo of

Transcription factors associated with GLIS1

Gene Symbol Gene ID Gene Info
GLIS1
ENSG00000174332.5 GLIS1

Activity profile of GLIS1 motif

Sorted Z-values of GLIS1 motif

Network of associatons between targets according to the STRING database.

Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_107044689 4.05 ENST00000265717.5
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
chr19_-_49325181 2.84 ENST00000454748.7
ENST00000335875.9
ENST00000598828.1
SLC6A16
solute carrier family 6 member 16
chr19_+_40191410 1.82 ENST00000253055.8
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr18_+_11752041 1.56 ENST00000423027.8
GNAL
G protein subunit alpha L
chr18_+_11751467 1.28 ENST00000535121.5
GNAL
G protein subunit alpha L
chr11_+_68903849 0.96 ENST00000675615.1
ENST00000255078.8
IGHMBP2
immunoglobulin mu DNA binding protein 2
chr19_-_41959266 0.48 ENST00000600292.5
ENST00000601078.5
ENST00000601891.5
ENST00000222008.11
RABAC1
Rab acceptor 1
chr18_+_11751494 0.42 ENST00000269162.9
GNAL
G protein subunit alpha L
chr16_+_58025745 0.38 ENST00000219271.4
MMP15
matrix metallopeptidase 15
chr19_+_1275508 0.14 ENST00000409293.6
FAM174C
family with sequence similarity 174 member C
chr18_-_63158208 0.08 ENST00000678301.1
BCL2
BCL2 apoptosis regulator
chr11_+_68684534 0.04 ENST00000265643.4
GAL
galanin and GMAP prepropeptide

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0097338 response to clozapine(GO:0097338)
0.2 1.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 3.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 2.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.0 GO:0051464 positive regulation of cortisol secretion(GO:0051464)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.0 GO:0032797 SMN complex(GO:0032797)
0.0 3.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 4.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 2.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 3.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 4.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB