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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GMEB1

Z-value: 2.00

Motif logo

Transcription factors associated with GMEB1

Gene Symbol Gene ID Gene Info
ENSG00000162419.13 GMEB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB1hg38_v1_chr1_+_28668746_286688150.228.6e-04Click!

Activity profile of GMEB1 motif

Sorted Z-values of GMEB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_36916298 13.32 ENST00000427117.5
ENST00000333987.12
ENST00000587130.5
ENST00000415168.5
ENST00000444991.5
zinc finger protein 568
chr18_+_657734 10.91 ENST00000323250.9
ENST00000323224.7
thymidylate synthetase
chr3_-_64023986 10.88 ENST00000394431.6
proteasome 26S subunit, non-ATPase 6
chr15_+_59105099 10.79 ENST00000288207.7
ENST00000559622.5
cyclin B2
chr13_+_52455429 10.68 ENST00000468284.1
ENST00000378034.7
ENST00000378037.9
ENST00000258607.10
cytoskeleton associated protein 2
chr18_+_657637 10.31 ENST00000323274.15
thymidylate synthetase
chr3_-_49029378 9.38 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr15_+_59105205 9.16 ENST00000621385.1
cyclin B2
chr3_+_197749855 9.09 ENST00000241502.9
forty-two-three domain containing 1
chr20_-_5126534 8.54 ENST00000379160.3
proliferating cell nuclear antigen
chr16_-_11276473 8.33 ENST00000241808.9
ENST00000435245.2
protamine 2
chr3_-_146544850 8.32 ENST00000472349.1
phospholipid scramblase 1
chr19_+_57240610 8.25 ENST00000414468.3
zinc finger protein 805
chr6_-_109382397 8.13 ENST00000512821.5
CD164 molecule
chr3_-_146544636 7.43 ENST00000486631.5
phospholipid scramblase 1
chr6_-_158644709 6.91 ENST00000367089.8
dynein light chain Tctex-type 1
chr7_+_12686849 6.86 ENST00000396662.5
ENST00000356797.7
ENST00000396664.2
ADP ribosylation factor like GTPase 4A
chr8_-_63038788 6.65 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr3_-_64023424 6.57 ENST00000478185.1
ENST00000482510.5
ENST00000497323.5
ENST00000492933.5
ENST00000295901.9
proteasome 26S subunit, non-ATPase 6
chr5_+_163460623 6.48 ENST00000393915.9
ENST00000432118.6
hyaluronan mediated motility receptor
chr19_+_36973211 6.44 ENST00000586353.5
ENST00000433993.5
ENST00000592567.1
zinc finger protein 568
chr7_+_141738321 6.23 ENST00000612337.4
single stranded DNA binding protein 1
chr7_+_141738343 6.21 ENST00000498107.5
ENST00000265304.11
ENST00000467681.5
ENST00000465582.5
ENST00000463093.5
single stranded DNA binding protein 1
chr3_+_160399630 6.21 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr8_-_116766255 6.08 ENST00000276682.8
eukaryotic translation initiation factor 3 subunit H
chrX_+_65667645 6.07 ENST00000360270.7
moesin
chr12_+_93467506 6.02 ENST00000549982.6
ENST00000552217.6
ENST00000393128.8
ENST00000547098.5
mitochondrial ribosomal protein L42
chr12_+_50112167 5.88 ENST00000548468.2
ENST00000552815.1
ENST00000550654.1
ENST00000550487.6
ENST00000548985.1
novel transcript, antisense to CERS5
cytochrome c oxidase assembly factor COX14
chr5_-_87412854 5.79 ENST00000504878.1
ENST00000256897.9
cyclin H
chr17_-_9575811 5.71 ENST00000306357.9
ENST00000574431.5
syntaxin 8
chrX_+_48574938 5.71 ENST00000376755.1
RNA binding motif protein 3
chr5_-_69369257 5.70 ENST00000509462.5
TATA-box binding protein associated factor 9
chr14_+_35122722 5.68 ENST00000605870.5
ENST00000557404.3
protein only RNase P catalytic subunit
chr2_-_99336306 5.65 ENST00000264255.8
ENST00000409434.5
ENST00000434323.5
thioredoxin domain containing 9
chr2_+_121737100 5.64 ENST00000455432.5
translin
chr4_-_103198331 5.60 ENST00000265148.9
ENST00000514974.1
centromere protein E
chr12_-_102061946 5.53 ENST00000240079.11
WASH complex subunit 3
chr1_+_86704892 5.53 ENST00000482504.1
SH3 domain containing GRB2 like, endophilin B1
chr3_+_133805789 5.53 ENST00000678299.1
SRP receptor subunit beta
chr10_+_5684828 5.50 ENST00000328090.9
ENST00000496681.5
transcription activation suppressor family member 2
chr7_+_56051685 5.49 ENST00000335503.3
chaperonin containing TCP1 subunit 6A
chr6_-_109382460 5.49 ENST00000310786.10
CD164 molecule
chr20_+_57351528 5.49 ENST00000395840.6
ribonucleic acid export 1
chr1_-_64966284 5.45 ENST00000671929.1
ENST00000673046.1
ENST00000672247.1
Janus kinase 1
chr11_+_61792878 5.34 ENST00000305885.3
ENST00000535723.1
flap structure-specific endonuclease 1
chr3_-_146544701 5.32 ENST00000487389.5
phospholipid scramblase 1
chr4_-_103198371 5.30 ENST00000611174.4
ENST00000380026.8
centromere protein E
chr4_+_112145445 5.27 ENST00000309733.6
family with sequence similarity 241 member A
chr1_-_65067707 5.23 ENST00000672099.1
ENST00000671954.1
ENST00000672434.1
ENST00000673502.1
ENST00000672751.1
Janus kinase 1
chr17_+_75205659 5.17 ENST00000583569.5
ENST00000245544.9
ENST00000579324.5
ENST00000579298.5
nucleoporin 85
chr3_+_152268920 5.16 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
muscleblind like splicing regulator 1
chr17_+_35587478 5.14 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr6_+_36594354 5.14 ENST00000373715.11
serine and arginine rich splicing factor 3
chr14_+_54396964 5.06 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr1_+_92832065 5.04 ENST00000315741.5
ribosomal protein L5
chr5_-_69369465 5.03 ENST00000508954.3
ENST00000512152.5
ENST00000503245.5
ENST00000217893.10
ENST00000618980.1
ENST00000502819.5
ENST00000380822.9
ENST00000512561.5
TATA-box binding protein associated factor 9
adenylate kinase 6
chr14_+_54397021 5.02 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr21_-_17612842 5.01 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr3_+_134486411 5.01 ENST00000682685.1
ENST00000684492.1
ENST00000682800.1
centrosomal protein 63
chr12_+_75391078 4.98 ENST00000550916.6
ENST00000378692.7
ENST00000320460.8
ENST00000547164.1
GLIPR1 like 2
chr5_+_163460650 4.96 ENST00000358715.3
hyaluronan mediated motility receptor
chr15_+_66505289 4.91 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr14_-_35121950 4.89 ENST00000554361.5
ENST00000261475.10
protein phosphatase 2 regulatory subunit B''gamma
chr9_-_92325577 4.86 ENST00000358855.8
ENST00000421075.6
ENST00000536624.5
nucleolar protein 8
chr14_+_35122660 4.80 ENST00000603544.5
protein only RNase P catalytic subunit
chr16_-_75647655 4.80 ENST00000570215.1
ENST00000319410.9
ENST00000302445.8
lysyl-tRNA synthetase 1
chr2_+_113437691 4.72 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
COBW domain containing 2
chrX_+_11758159 4.68 ENST00000361672.6
ENST00000337339.7
ENST00000647869.1
ENST00000312196.10
ENST00000647857.1
ENST00000649130.1
MSL complex subunit 3
chr6_+_80004615 4.67 ENST00000369798.7
ENST00000502580.5
ENST00000511260.5
TTK protein kinase
chr4_-_47463649 4.65 ENST00000381571.6
COMM domain containing 8
chr5_-_179624578 4.62 ENST00000505811.5
ENST00000515714.5
ENST00000513225.5
ENST00000503664.1
ENST00000356731.9
ENST00000523137.5
heterogeneous nuclear ribonucleoprotein H1
chr14_+_58244821 4.59 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
proteasome 20S subunit alpha 3
chr14_+_61762405 4.59 ENST00000216294.5
small nuclear RNA activating complex polypeptide 1
chr12_-_102062079 4.54 ENST00000545679.5
WASH complex subunit 3
chr2_-_61888570 4.52 ENST00000394440.8
ENST00000544079.2
chaperonin containing TCP1 subunit 4
chr6_-_109382431 4.49 ENST00000324953.9
ENST00000275080.11
ENST00000413644.6
CD164 molecule
chr10_-_43397220 4.46 ENST00000477108.5
ENST00000544000.5
heterogeneous nuclear ribonucleoprotein F
chr7_+_87876472 4.46 ENST00000265728.6
DBF4 zinc finger
chr11_+_95790459 4.45 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
centrosomal protein 57
chr8_+_33485173 4.45 ENST00000360128.11
MAK16 homolog
chr17_-_75154503 4.44 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr1_+_46203321 4.43 ENST00000371980.4
leucine rich adaptor protein 1
chr6_+_116571390 4.42 ENST00000368590.9
RWD domain containing 1
chr14_+_73886805 4.41 ENST00000324593.10
ENST00000557495.5
ENST00000556659.5
ENST00000555044.6
ENST00000442160.7
zinc finger protein 410
chr2_+_171922442 4.41 ENST00000264108.5
histone acetyltransferase 1
chr16_-_75647624 4.40 ENST00000568378.5
ENST00000568682.5
lysyl-tRNA synthetase 1
chr2_+_218217131 4.40 ENST00000420104.5
ENST00000315717.10
ENST00000295685.14
actin related protein 2/3 complex subunit 2
chr13_-_37059603 4.34 ENST00000497318.1
ENST00000475892.5
ENST00000356185.7
ENST00000350612.11
ENST00000360252.8
SPT20 homolog, SAGA complex component
chr14_+_73886617 4.32 ENST00000540593.5
ENST00000555730.6
zinc finger protein 410
chr20_+_43590912 4.30 ENST00000373030.8
ENST00000373039.4
intraflagellar transport 52
chr11_-_58578096 4.30 ENST00000528954.5
ENST00000528489.1
leupaxin
chr18_+_65750628 4.24 ENST00000536984.6
cadherin 7
chr6_-_41071825 4.23 ENST00000468811.5
O-acyl-ADP-ribose deacylase 1
chr5_+_10250216 4.20 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr17_-_75154534 4.18 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr20_-_56392131 4.16 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr13_-_52129051 4.16 ENST00000652119.1
ENST00000647945.1
ENST00000355568.8
NIMA related kinase 5
chr11_+_95790659 4.12 ENST00000538658.5
centrosomal protein 57
chr11_-_65900413 4.12 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr6_+_29723421 4.12 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr3_-_30894661 4.11 ENST00000282538.10
ENST00000454381.3
glutamate decarboxylase like 1
chr7_+_120950763 4.10 ENST00000339121.9
ENST00000315870.10
ENST00000445699.5
inhibitor of growth family member 3
chr15_+_66504959 4.10 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr8_+_26291758 4.05 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr10_-_5889832 4.03 ENST00000380092.8
ENST00000380094.10
ENST00000191063.8
ankyrin repeat domain 16
chr21_-_39183466 4.00 ENST00000380900.2
proteasome assembly chaperone 1
chr2_-_38751350 3.97 ENST00000409276.5
ENST00000313117.11
ENST00000446327.6
serine and arginine rich splicing factor 7
chr2_+_26786020 3.95 ENST00000335756.9
ENST00000233505.12
centromere protein A
chr19_+_57320461 3.95 ENST00000321545.5
zinc finger protein 543
chr11_+_65570452 3.94 ENST00000531405.5
ENST00000309328.8
ENST00000527920.5
ENST00000526877.1
ENST00000533115.5
ENST00000526433.1
zinc ribbon domain containing 2
chr20_+_57351218 3.92 ENST00000371242.6
ENST00000527947.5
ENST00000395841.7
ribonucleic acid export 1
chr3_+_133574434 3.91 ENST00000508481.5
ENST00000420115.6
ENST00000504867.5
ENST00000507408.5
ENST00000511392.5
ENST00000515421.1
CDV3 homolog
chr10_+_68956158 3.90 ENST00000354185.9
DExD-box helicase 21
chr8_-_143617498 3.88 ENST00000425753.7
GDP-L-fucose synthase
chr18_-_49492305 3.85 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
ribosomal protein L17
RPL17-C18orf32 readthrough
chr17_+_82237134 3.84 ENST00000583025.1
solute carrier family 16 member 3
chr3_-_32502783 3.83 ENST00000205636.4
CKLF like MARVEL transmembrane domain containing 6
chrY_+_6246223 3.82 ENST00000429039.5
ENST00000320701.8
ENST00000383042.1
testis specific protein Y-linked 2
chr22_-_30591850 3.82 ENST00000335214.8
ENST00000406208.7
ENST00000402284.7
ENST00000354694.12
pescadillo ribosomal biogenesis factor 1
chr3_-_149086488 3.74 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
helicase like transcription factor
chr10_-_17617326 3.69 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr20_-_5119945 3.68 ENST00000379143.10
proliferating cell nuclear antigen
chr9_+_107283256 3.68 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr6_+_87590067 3.66 ENST00000546266.5
ENST00000257789.4
ENST00000392844.8
origin recognition complex subunit 3
chr4_+_109560219 3.66 ENST00000394650.7
mitochondrial calcium uniporter dominant negative subunit beta
chr7_+_116525028 3.63 ENST00000341049.7
caveolin 1
chr10_+_123154414 3.63 ENST00000368858.9
BUB3 mitotic checkpoint protein
chr16_-_2980282 3.60 ENST00000572619.1
ENST00000574415.5
ENST00000440027.6
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr6_+_44223553 3.59 ENST00000371740.10
ENST00000371755.9
ENST00000643869.1
ENST00000371731.6
solute carrier family 29 member 1 (Augustine blood group)
chr15_+_78540729 3.58 ENST00000559365.5
ENST00000558341.5
ENST00000559437.5
proteasome 20S subunit alpha 4
chr15_+_30903849 3.58 ENST00000561594.5
ENST00000658773.1
ENST00000657391.1
ENST00000656435.1
FANCD2 and FANCI associated nuclease 1
chr2_-_55269207 3.55 ENST00000263629.9
ENST00000403721.5
mitochondrial translational initiation factor 2
chr21_+_46098102 3.53 ENST00000300527.9
ENST00000310645.9
collagen type VI alpha 2 chain
chr9_-_92325322 3.50 ENST00000542613.5
ENST00000542053.5
ENST00000442668.7
ENST00000545558.5
ENST00000432670.6
ENST00000433029.6
ENST00000411621.6
nucleolar protein 8
chr12_+_69739370 3.50 ENST00000550536.5
ENST00000362025.9
RAB3A interacting protein
chr8_+_90001448 3.49 ENST00000519410.5
ENST00000522161.5
ENST00000220764.7
ENST00000517761.5
ENST00000520227.1
2,4-dienoyl-CoA reductase 1
chr7_+_116525524 3.49 ENST00000405348.6
caveolin 1
chr6_-_152983031 3.49 ENST00000229758.8
F-box protein 5
chr6_+_73461578 3.48 ENST00000415954.6
ENST00000681204.1
ENST00000680686.1
ENST00000521156.6
ENST00000498286.6
ENST00000370305.5
ENST00000370300.8
mitochondrial tRNA translation optimization 1
chr7_+_56051756 3.46 ENST00000275603.9
chaperonin containing TCP1 subunit 6A
chr5_+_10250272 3.42 ENST00000280326.9
ENST00000625723.1
chaperonin containing TCP1 subunit 5
chr1_-_246566238 3.40 ENST00000366514.5
transcription factor B2, mitochondrial
chr5_+_76716094 3.39 ENST00000319211.5
coagulation factor II thrombin receptor
chr18_+_32092610 3.37 ENST00000578107.5
ENST00000257190.9
ENST00000580499.1
ring finger protein 138
chr16_-_2980406 3.35 ENST00000431515.6
ENST00000574385.5
ENST00000576268.1
ENST00000574730.5
ENST00000262300.13
ENST00000575632.5
ENST00000573944.5
protein kinase, membrane associated tyrosine/threonine 1
chr10_+_28533706 3.33 ENST00000442148.6
ENST00000448193.5
WW domain containing adaptor with coiled-coil
chr19_-_10334723 3.33 ENST00000592945.1
intercellular adhesion molecule 3
chr5_-_98928992 3.33 ENST00000614616.5
chromodomain helicase DNA binding protein 1
chr6_+_133953210 3.32 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr1_-_70205531 3.30 ENST00000370952.4
leucine rich repeat containing 40
chr8_-_80029904 3.30 ENST00000521434.5
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr8_+_70669330 3.29 ENST00000408926.8
ENST00000520030.5
ENST00000647843.1
XK related 9
novel transcript
chr15_+_30903877 3.27 ENST00000670849.1
ENST00000561607.6
ENST00000565466.5
ENST00000664837.1
ENST00000362065.9
ENST00000666143.1
FANCD2 and FANCI associated nuclease 1
chr2_+_88691647 3.26 ENST00000283646.5
ribose 5-phosphate isomerase A
chr6_-_152983561 3.25 ENST00000367241.3
F-box protein 5
chr3_+_133573637 3.24 ENST00000264993.8
CDV3 homolog
chr3_-_146544538 3.22 ENST00000462666.5
phospholipid scramblase 1
chr3_+_36993764 3.22 ENST00000674019.1
ENST00000458205.6
mutL homolog 1
chr19_-_22784091 3.21 ENST00000596209.4
zinc finger protein 99
chr6_+_29723340 3.19 ENST00000334668.8
major histocompatibility complex, class I, F
chr7_+_73683588 3.18 ENST00000265758.7
ENST00000441822.5
ENST00000423497.5
BUD23 rRNA methyltransferase and ribosome maturation factor
chr13_+_102596972 3.16 ENST00000376052.5
ENST00000376065.8
ENST00000652308.1
ENST00000651544.1
tripeptidyl peptidase 2
chr17_+_59893046 3.16 ENST00000393021.7
ENST00000225577.9
ENST00000443572.6
ENST00000406116.7
ribosomal protein S6 kinase B1
chr11_-_65900375 3.16 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr2_+_27212320 3.15 ENST00000405489.7
all-trans retinoic acid induced differentiation factor
chr1_+_112619824 3.15 ENST00000263168.4
capping actin protein of muscle Z-line subunit alpha 1
chr4_+_56977710 3.15 ENST00000450656.5
ENST00000381227.5
RNA polymerase II subunit B
chr15_+_32718476 3.14 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr6_-_52577012 3.12 ENST00000182527.4
translocation associated membrane protein 2
chr12_-_47079926 3.10 ENST00000429635.1
ENST00000550413.2
adhesion molecule with Ig like domain 2
chr3_+_179653129 3.10 ENST00000680008.1
ubiquitin specific peptidase 13
chr4_-_185425941 3.07 ENST00000264689.11
ENST00000505357.1
UFM1 specific peptidase 2
chrX_-_152769677 3.07 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr13_-_37059432 3.06 ENST00000464744.5
SPT20 homolog, SAGA complex component
chr2_+_237692290 3.05 ENST00000420665.5
ENST00000392000.4
LRR binding FLII interacting protein 1
chr13_-_23375431 3.03 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr18_-_61892997 3.02 ENST00000312828.4
ring finger protein 152
chr9_+_128456418 3.02 ENST00000434106.7
ENST00000546203.5
ENST00000446274.5
ENST00000421776.6
ENST00000432065.6
outer dense fiber of sperm tails 2
chr5_+_43121596 2.99 ENST00000505606.6
ENST00000509634.5
ENST00000509341.5
zinc finger protein 131
chr6_-_31958852 2.99 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr11_-_14520323 2.98 ENST00000530457.5
ENST00000532256.1
ENST00000396394.7
proteasome 20S subunit alpha 1
chr3_+_197950176 2.96 ENST00000448864.6
ENST00000647248.2
ribosomal protein L35a
chr17_+_42609641 2.93 ENST00000681413.1
ENST00000251413.8
ENST00000591509.5
tubulin gamma 1
chr10_+_28533480 2.92 ENST00000651885.1
ENST00000651441.1
ENST00000679398.1
WW domain containing adaptor with coiled-coil
chr1_+_182839338 2.89 ENST00000367549.4
DExH-box helicase 9
chr14_+_51240205 2.89 ENST00000457354.7
thioredoxin related transmembrane protein 1
chr1_+_92832005 2.88 ENST00000645300.1
ribosomal protein L5
chr2_+_108534353 2.88 ENST00000544547.5
LIM zinc finger domain containing 1
chr2_-_233854566 2.87 ENST00000432087.5
ENST00000441687.5
ENST00000414924.5
Holliday junction recognition protein
chr2_-_233854506 2.87 ENST00000411486.7
Holliday junction recognition protein
chr4_+_112637120 2.87 ENST00000509061.5
ENST00000344442.10
ENST00000508577.5
ENST00000513553.5
La ribonucleoprotein 7, transcriptional regulator
chr6_-_31958935 2.86 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr16_-_20741792 2.84 ENST00000396083.7
THUMP domain containing 1
chr2_-_87825952 2.83 ENST00000398146.4
RANBP2 like and GRIP domain containing 2
chr1_+_92832028 2.82 ENST00000370321.8
ENST00000645119.1
ribosomal protein L5
chr3_-_131502946 2.82 ENST00000512877.1
ENST00000264995.8
ENST00000511168.5
ENST00000425847.6
mitochondrial ribosomal protein L3
chr3_+_33114033 2.82 ENST00000449224.1
cartilage associated protein
chr3_-_47781837 2.81 ENST00000254480.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr19_+_57191464 2.81 ENST00000263095.10
ENST00000594126.1
ENST00000600531.5
ENST00000597447.5
ENST00000599653.1
zinc finger protein 264
chr8_+_116766497 2.80 ENST00000517814.1
ENST00000309822.7
ENST00000517820.1
UTP23 small subunit processome component

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 21.2 GO:0019860 uracil metabolic process(GO:0019860)
3.6 10.9 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
3.1 12.2 GO:0006272 leading strand elongation(GO:0006272)
3.0 24.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
2.7 10.7 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
2.4 9.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
2.0 6.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
1.9 9.4 GO:0006177 GMP biosynthetic process(GO:0006177)
1.8 5.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.8 10.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
1.8 7.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.7 8.7 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
1.7 23.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
1.6 8.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
1.6 4.7 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
1.6 4.7 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.6 14.0 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.4 5.6 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.4 6.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.3 7.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.2 3.7 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
1.2 3.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.2 7.3 GO:0007296 vitellogenesis(GO:0007296)
1.2 4.7 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
1.2 3.5 GO:0036233 glycine import(GO:0036233)
1.2 12.9 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.2 5.8 GO:0015862 uridine transport(GO:0015862)
1.2 5.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.2 6.9 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.1 3.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.1 3.4 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
1.1 10.0 GO:0098535 de novo centriole assembly(GO:0098535)
1.1 8.9 GO:0007506 gonadal mesoderm development(GO:0007506)
1.1 3.2 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
1.1 7.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
1.1 3.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
1.1 3.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of skeletal muscle tissue growth(GO:0048633)
1.0 1.0 GO:1904882 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
1.0 6.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.0 14.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
1.0 6.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.0 3.0 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
1.0 3.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
1.0 2.0 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.9 8.4 GO:1902570 protein localization to nucleolus(GO:1902570)
0.9 2.8 GO:0046967 cytosol to ER transport(GO:0046967)
0.9 2.7 GO:0002326 B cell lineage commitment(GO:0002326)
0.9 11.9 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.9 3.5 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.9 1.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.9 4.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.9 2.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.8 3.4 GO:1901143 insulin catabolic process(GO:1901143)
0.8 3.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.8 2.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 3.2 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.8 1.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.8 2.4 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.8 5.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.7 2.2 GO:1904387 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.7 4.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.7 0.7 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.7 7.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.7 2.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.7 2.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.7 3.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.7 2.1 GO:0042323 germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) deoxyribonucleoside catabolic process(GO:0046121) negative regulation of mucus secretion(GO:0070256)
0.7 9.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.7 5.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.7 2.7 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.7 3.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.7 2.7 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.7 4.0 GO:0043248 proteasome assembly(GO:0043248)
0.7 2.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.7 2.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.7 2.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.6 2.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.6 3.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.6 1.9 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.6 4.9 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.6 1.8 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.6 1.8 GO:2000276 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.6 1.8 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.6 1.8 GO:0046521 sphingoid catabolic process(GO:0046521)
0.6 1.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.6 1.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.6 1.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.6 2.8 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.5 1.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.5 0.5 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.5 3.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.5 1.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.5 1.6 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5 11.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.5 1.0 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.5 1.5 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.5 1.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.5 2.0 GO:0007144 female meiosis I(GO:0007144)
0.5 0.5 GO:2000232 regulation of rRNA processing(GO:2000232)
0.5 7.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.5 3.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.5 1.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.5 1.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.5 19.9 GO:0043029 T cell homeostasis(GO:0043029)
0.5 5.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.5 2.8 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.5 2.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 3.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4 2.7 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.4 4.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4 15.0 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.4 2.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.4 2.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.4 3.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.4 1.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 2.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 7.7 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.4 1.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4 10.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 6.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 6.8 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.4 2.3 GO:0035617 stress granule disassembly(GO:0035617)
0.4 2.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 3.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.4 1.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.4 1.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.4 1.8 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.4 1.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 2.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 2.8 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 8.3 GO:0030261 chromosome condensation(GO:0030261)
0.3 22.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 2.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.3 36.9 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.3 1.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.3 1.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.3 1.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 1.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.3 1.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.3 1.6 GO:0030242 pexophagy(GO:0030242)
0.3 1.0 GO:0061074 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.3 2.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.3 1.3 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 6.0 GO:0003334 keratinocyte development(GO:0003334)
0.3 0.9 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 3.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 0.9 GO:1901355 response to rapamycin(GO:1901355)
0.3 1.5 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 3.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 3.7 GO:0051382 kinetochore assembly(GO:0051382)
0.3 1.2 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.3 2.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.3 3.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3 0.9 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.3 0.6 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 0.9 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3 2.0 GO:0016584 nucleosome positioning(GO:0016584)
0.3 21.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 5.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.3 1.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 9.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 1.4 GO:0006013 mannose metabolic process(GO:0006013)
0.3 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 2.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.3 1.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.3 2.4 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.3 0.8 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.3 1.0 GO:0009838 abscission(GO:0009838)
0.3 2.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 1.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 0.8 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.3 1.8 GO:0090400 stress-induced premature senescence(GO:0090400)
0.3 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.5 GO:0015853 adenine transport(GO:0015853)
0.3 2.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 3.5 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.7 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 4.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 1.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.2 1.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.2 1.0 GO:0051586 positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.2 0.7 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 4.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 8.5 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 2.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 2.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 0.7 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.2 0.7 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 1.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 1.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 1.8 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.2 0.2 GO:1990592 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 2.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 3.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.6 GO:0080009 mRNA methylation(GO:0080009)
0.2 0.6 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.2 2.3 GO:0016180 snRNA processing(GO:0016180)
0.2 8.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 1.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 28.1 GO:0045047 protein targeting to ER(GO:0045047)
0.2 7.0 GO:0006301 postreplication repair(GO:0006301)
0.2 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.2 0.6 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 3.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 0.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 6.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 2.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 1.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 4.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 1.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 0.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.2 0.7 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 1.6 GO:0046070 dGTP metabolic process(GO:0046070)
0.2 36.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.2 0.7 GO:0090289 regulation of osteoclast proliferation(GO:0090289)
0.2 1.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 5.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.3 GO:0006404 RNA import into nucleus(GO:0006404)
0.2 4.4 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.9 GO:0045116 protein neddylation(GO:0045116)
0.2 0.3 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2 3.4 GO:0034453 microtubule anchoring(GO:0034453)
0.2 2.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 2.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 0.6 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 1.3 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.2 2.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.2 2.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 2.1 GO:0006983 ER overload response(GO:0006983)
0.2 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 1.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 14.3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 0.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 1.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 3.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.2 0.8 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.2 1.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.2 0.6 GO:0048254 snoRNA localization(GO:0048254)
0.1 6.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.2 GO:0006228 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228)
0.1 0.7 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 2.3 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 2.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 2.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 7.3 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.9 GO:0015705 iodide transport(GO:0015705)
0.1 2.7 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 1.2 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 2.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 3.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.5 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1 0.5 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.7 GO:0000732 strand displacement(GO:0000732)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 2.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 1.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 2.0 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.9 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 1.0 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 0.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 2.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 1.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 2.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.4 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.5 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0042407 cristae formation(GO:0042407)
0.1 1.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 3.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.2 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.7 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 2.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.3 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.7 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.2 GO:0048539 bone marrow development(GO:0048539)
0.1 0.4 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 1.0 GO:0010452 histone H3-K36 methylation(GO:0010452) peptidyl-lysine monomethylation(GO:0018026) peptidyl-lysine dimethylation(GO:0018027)
0.1 2.5 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.1 GO:0071888 macrophage apoptotic process(GO:0071888)
0.1 0.2 GO:0002357 defense response to tumor cell(GO:0002357)
0.1 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.8 GO:0006999 nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 1.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 5.1 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 2.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 4.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.8 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 1.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 1.3 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 1.6 GO:0010259 multicellular organism aging(GO:0010259)
0.1 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 3.5 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 2.8 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 1.6 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.5 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.6 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.3 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.4 GO:0039536 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 1.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 1.1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 4.4 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.4 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.7 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.7 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 2.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.5 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.8 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.3 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.0 0.8 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0014856 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) positive regulation of myoblast proliferation(GO:2000288)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.3 GO:0030307 positive regulation of cell growth(GO:0030307)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 12.2 GO:0070557 PCNA-p21 complex(GO:0070557)
2.3 9.0 GO:1990423 RZZ complex(GO:1990423)
1.9 5.7 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
1.5 6.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.5 4.5 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
1.5 13.3 GO:0000125 PCAF complex(GO:0000125)
1.5 4.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.4 26.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
1.2 3.7 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.2 13.8 GO:0071203 WASH complex(GO:0071203)
1.1 13.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.1 8.7 GO:0000796 condensin complex(GO:0000796)
0.9 11.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 4.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.9 2.8 GO:0071001 U4/U6 snRNP(GO:0071001)
0.9 3.7 GO:1990246 uniplex complex(GO:1990246)
0.9 4.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.9 6.1 GO:0032021 NELF complex(GO:0032021)
0.9 2.6 GO:0034455 t-UTP complex(GO:0034455)
0.8 3.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.8 8.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.8 3.2 GO:0005715 late recombination nodule(GO:0005715)
0.7 3.0 GO:0071942 XPC complex(GO:0071942)
0.7 2.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.7 4.3 GO:0070545 PeBoW complex(GO:0070545)
0.7 2.1 GO:0032426 stereocilium tip(GO:0032426)
0.7 2.0 GO:0030689 Noc complex(GO:0030689)
0.7 3.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.7 13.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.7 18.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.7 2.0 GO:0097229 sperm end piece(GO:0097229)
0.7 7.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.7 9.9 GO:0005675 holo TFIIH complex(GO:0005675)
0.6 3.8 GO:0002177 manchette(GO:0002177)
0.6 3.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.6 1.8 GO:0031251 PAN complex(GO:0031251)
0.6 3.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.6 18.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.6 4.7 GO:0072487 MSL complex(GO:0072487)
0.6 2.2 GO:0035061 Smc5-Smc6 complex(GO:0030915) interchromatin granule(GO:0035061)
0.6 2.2 GO:0035363 histone locus body(GO:0035363)
0.6 5.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.6 2.8 GO:0042825 TAP complex(GO:0042825)
0.5 7.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 1.6 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.5 1.6 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.5 1.6 GO:0036284 tubulobulbar complex(GO:0036284)
0.5 2.1 GO:0071920 cleavage body(GO:0071920)
0.5 2.0 GO:0000811 GINS complex(GO:0000811)
0.5 2.5 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5 25.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 2.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.5 8.3 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.5 5.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 5.9 GO:0005688 U6 snRNP(GO:0005688)
0.4 2.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 3.0 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.4 2.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.4 1.6 GO:0033263 CORVET complex(GO:0033263)
0.4 4.3 GO:0000124 SAGA complex(GO:0000124)
0.4 1.1 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.4 1.9 GO:0001652 granular component(GO:0001652)
0.4 3.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 2.9 GO:0005827 polar microtubule(GO:0005827)
0.4 4.3 GO:0044292 dendrite terminus(GO:0044292)
0.3 1.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 5.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 7.1 GO:0036020 endolysosome membrane(GO:0036020)
0.3 3.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.3 5.1 GO:0031932 TORC2 complex(GO:0031932)
0.3 1.2 GO:0031298 replication fork protection complex(GO:0031298)
0.3 1.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 2.5 GO:0005787 signal peptidase complex(GO:0005787)
0.3 0.8 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.3 1.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 2.4 GO:0070652 HAUS complex(GO:0070652)
0.3 6.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 38.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.3 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 2.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 4.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 3.5 GO:0001741 XY body(GO:0001741)
0.2 1.7 GO:0016589 NURF complex(GO:0016589)
0.2 0.7 GO:0035517 PR-DUB complex(GO:0035517)
0.2 4.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 1.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 2.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 4.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.5 GO:0016272 prefoldin complex(GO:0016272)
0.2 2.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 2.3 GO:0032039 integrator complex(GO:0032039)
0.2 1.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 1.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 5.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 3.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.8 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 2.1 GO:0000974 Prp19 complex(GO:0000974)
0.2 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 2.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 2.9 GO:0034709 methylosome(GO:0034709)
0.2 4.5 GO:0035861 site of double-strand break(GO:0035861)
0.2 2.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.2 1.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.8 GO:0005686 U2 snRNP(GO:0005686)
0.2 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 4.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 8.1 GO:0005844 polysome(GO:0005844)
0.2 4.1 GO:0032040 small-subunit processome(GO:0032040)
0.2 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.2 3.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 10.0 GO:0045171 intercellular bridge(GO:0045171)
0.2 4.6 GO:0000421 autophagosome membrane(GO:0000421)
0.2 0.6 GO:0005846 nuclear cap binding complex(GO:0005846)
0.2 0.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 0.6 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 9.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 17.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 2.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 13.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.6 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 1.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 3.6 GO:0031094 platelet dense tubular network(GO:0031094)
0.1 0.5 GO:0022624 proteasome accessory complex(GO:0022624)
0.1 11.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 3.8 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0045160 myosin I complex(GO:0045160)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 31.5 GO:0005819 spindle(GO:0005819)
0.1 0.8 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 8.1 GO:0005681 spliceosomal complex(GO:0005681)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.3 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 4.5 GO:0002102 podosome(GO:0002102)
0.1 1.3 GO:0015030 Cajal body(GO:0015030)
0.1 2.7 GO:0032420 stereocilium(GO:0032420)
0.1 3.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 26.1 GO:0005813 centrosome(GO:0005813)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.5 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 5.0 GO:0042641 actomyosin(GO:0042641)
0.0 2.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 6.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 5.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 36.8 GO:0005730 nucleolus(GO:0005730)
0.0 2.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 2.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0030880 DNA-directed RNA polymerase complex(GO:0000428) RNA polymerase complex(GO:0030880) nuclear DNA-directed RNA polymerase complex(GO:0055029)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.2 GO:0031514 motile cilium(GO:0031514)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.7 10.9 GO:0043515 kinetochore binding(GO:0043515)
2.6 10.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
2.3 9.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
2.3 6.8 GO:0070336 flap-structured DNA binding(GO:0070336)
2.2 28.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.8 17.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.8 7.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.8 10.5 GO:0046979 TAP2 binding(GO:0046979)
1.7 5.2 GO:0001069 regulatory region RNA binding(GO:0001069)
1.5 13.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.5 23.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.4 8.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
1.4 5.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.4 4.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.3 3.9 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
1.3 7.6 GO:0005047 signal recognition particle binding(GO:0005047)
1.3 5.0 GO:0033677 DNA/RNA helicase activity(GO:0033677)
1.2 3.5 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
1.1 3.4 GO:0031626 beta-endorphin binding(GO:0031626)
1.1 3.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.9 5.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.9 2.7 GO:0004132 dCMP deaminase activity(GO:0004132)
0.9 2.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.8 7.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.8 2.4 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.8 2.4 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.8 3.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.7 2.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.7 2.2 GO:0098808 mRNA cap binding(GO:0098808)
0.7 1.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.7 2.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.7 2.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 2.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.7 4.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.7 2.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.7 2.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.7 2.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.6 3.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.6 1.8 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.6 2.3 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.6 2.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.6 3.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.6 2.8 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.5 2.2 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.5 1.6 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.5 2.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.5 3.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.5 4.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 4.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.5 17.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 3.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.5 4.5 GO:0043184 morphogen activity(GO:0016015) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 2.5 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.5 5.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.5 1.4 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.5 1.9 GO:0043273 CTPase activity(GO:0043273)
0.5 1.9 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.5 2.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.5 5.9 GO:0046870 cadmium ion binding(GO:0046870)
0.4 4.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4 5.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 3.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 12.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 1.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.4 9.4 GO:0008242 omega peptidase activity(GO:0008242)
0.4 3.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 4.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 3.8 GO:0045545 syndecan binding(GO:0045545)
0.4 5.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 1.7 GO:0035500 MH2 domain binding(GO:0035500)
0.4 2.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 1.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 2.7 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.4 3.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.4 1.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 4.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.4 11.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 2.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.4 3.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 6.6 GO:0070628 proteasome binding(GO:0070628)
0.3 10.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 3.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 6.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.3 12.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 1.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.3 1.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 4.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 2.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 0.6 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.3 4.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 3.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 5.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 3.1 GO:0000405 bubble DNA binding(GO:0000405)
0.3 1.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.3 1.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 0.9 GO:0000035 acyl binding(GO:0000035)
0.3 2.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.3 0.9 GO:0051717 phosphohistidine phosphatase activity(GO:0008969) bisphosphoglycerate phosphatase activity(GO:0034416) inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.3 2.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 0.9 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3 8.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 2.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 2.3 GO:0036310 annealing helicase activity(GO:0036310)
0.3 2.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 0.9 GO:0016154 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.3 6.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 0.8 GO:0097677 STAT family protein binding(GO:0097677)
0.3 37.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 1.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 17.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 0.8 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 0.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 3.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 1.8 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 2.7 GO:0004673 protein histidine kinase activity(GO:0004673)
0.2 3.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 2.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 5.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 2.9 GO:0008494 translation activator activity(GO:0008494)
0.2 2.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 5.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 3.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 6.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.7 GO:0008097 5S rRNA binding(GO:0008097)
0.2 4.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 1.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 5.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 2.6 GO:0031386 protein tag(GO:0031386)
0.2 3.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 3.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 13.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 2.7 GO:0016421 CoA carboxylase activity(GO:0016421)
0.2 3.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 9.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 2.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 10.2 GO:0031491 nucleosome binding(GO:0031491)
0.2 1.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.8 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 1.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 0.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 0.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.2 2.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 0.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 2.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 10.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 3.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 1.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 2.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 27.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 1.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.2 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.7 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 4.7 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 2.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 2.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.6 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.3 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 2.0 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 6.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.9 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 2.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.1 0.9 GO:0031433 telethonin binding(GO:0031433)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 3.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.0 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 8.5 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 4.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 3.5 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 2.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.6 GO:0004527 exonuclease activity(GO:0004527)
0.0 3.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 7.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 5.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 3.7 GO:0003774 motor activity(GO:0003774)
0.0 30.8 GO:0003723 RNA binding(GO:0003723)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 13.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 25.4 PID AURORA B PATHWAY Aurora B signaling
0.3 11.5 PID MYC PATHWAY C-MYC pathway
0.3 20.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 1.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 27.1 PID E2F PATHWAY E2F transcription factor network
0.3 7.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 12.5 PID BARD1 PATHWAY BARD1 signaling events
0.2 12.7 PID PLK1 PATHWAY PLK1 signaling events
0.2 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 12.9 PID P53 REGULATION PATHWAY p53 pathway
0.2 7.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 1.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 8.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 6.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 3.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 9.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 4.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 4.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.8 PID EPO PATHWAY EPO signaling pathway
0.1 6.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 6.2 PID P73PATHWAY p73 transcription factor network
0.1 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.5 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 3.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.7 PID BMP PATHWAY BMP receptor signaling
0.1 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 6.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 20.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.3 30.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.2 35.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.8 12.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.8 13.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.7 23.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.7 7.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.6 17.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.6 20.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.6 4.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.5 2.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 11.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 35.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.5 10.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 6.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 5.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 7.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 49.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.3 3.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.3 7.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3 6.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 35.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 5.1 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.2 4.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 2.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 0.9 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 3.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 4.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 0.6 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.2 5.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 7.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 4.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 7.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 0.6 REACTOME NUCLEOTIDE EXCISION REPAIR Genes involved in Nucleotide Excision Repair
0.2 1.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 4.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 6.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.2 4.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 1.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 7.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 2.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 1.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 9.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 8.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.1 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 4.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.6 REACTOME KINESINS Genes involved in Kinesins
0.1 8.8 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 2.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 2.2 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.1 4.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.6 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 2.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME TRANSLATION Genes involved in Translation
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.6 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events