Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for GUAAACA
Z-value: 3.70
Motif logo
miRNA associated with seed GUAAACA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-30a-5p
|
MIMAT0000087 |
|
hsa-miR-30b-5p
|
MIMAT0000420 |
|
hsa-miR-30c-5p
|
MIMAT0000244 |
|
hsa-miR-30d-5p
|
MIMAT0000245 |
|
hsa-miR-30e-5p
|
MIMAT0000692 |
Activity profile of GUAAACA motif
Sorted Z-values of GUAAACA motif
Network of associatons between targets according to the STRING database.
First level regulatory network of GUAAACA
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_18097763 | 13.04 |
ENST00000262811.10
|
MAST3
|
microtubule associated serine/threonine kinase 3 |
| chr17_-_76240478 | 10.20 |
ENST00000269391.11
|
RNF157
|
ring finger protein 157 |
| chr8_+_24914942 | 9.72 |
ENST00000433454.3
|
NEFM
|
neurofilament medium |
| chr5_+_176365455 | 8.32 |
ENST00000310389.6
|
ARL10
|
ADP ribosylation factor like GTPase 10 |
| chr3_+_196744 | 7.74 |
ENST00000256509.7
ENST00000397491.6 |
CHL1
|
cell adhesion molecule L1 like |
| chrX_-_136767322 | 7.61 |
ENST00000370620.5
|
ARHGEF6
|
Rac/Cdc42 guanine nucleotide exchange factor 6 |
| chr4_+_157220691 | 7.39 |
ENST00000509417.5
ENST00000645636.1 ENST00000296526.12 ENST00000264426.14 |
GRIA2
|
glutamate ionotropic receptor AMPA type subunit 2 |
| chr18_+_56651335 | 7.37 |
ENST00000589935.1
ENST00000254442.8 ENST00000357574.7 |
WDR7
|
WD repeat domain 7 |
| chr3_-_18425295 | 7.37 |
ENST00000338745.11
ENST00000450898.1 |
SATB1
|
SATB homeobox 1 |
| chr18_+_26226417 | 7.20 |
ENST00000269142.10
|
TAF4B
|
TATA-box binding protein associated factor 4b |
| chr2_-_86337654 | 7.18 |
ENST00000165698.9
|
REEP1
|
receptor accessory protein 1 |
| chr19_+_18153155 | 7.14 |
ENST00000222254.13
|
PIK3R2
|
phosphoinositide-3-kinase regulatory subunit 2 |
| chr12_+_76764109 | 6.76 |
ENST00000426126.7
|
ZDHHC17
|
zinc finger DHHC-type palmitoyltransferase 17 |
| chr7_+_65873068 | 6.46 |
ENST00000360768.5
|
VKORC1L1
|
vitamin K epoxide reductase complex subunit 1 like 1 |
| chr16_+_66880503 | 6.44 |
ENST00000568869.1
ENST00000311765.4 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1 |
PDP2
|
pyruvate dehyrogenase phosphatase catalytic subunit 2 |
| chr11_-_134411854 | 6.29 |
ENST00000392580.5
|
B3GAT1
|
beta-1,3-glucuronyltransferase 1 |
| chr20_+_56358938 | 6.01 |
ENST00000371384.4
ENST00000437418.1 |
FAM210B
|
family with sequence similarity 210 member B |
| chr15_+_31326807 | 5.95 |
ENST00000307145.4
|
KLF13
|
Kruppel like factor 13 |
| chr20_+_59933761 | 5.89 |
ENST00000358293.7
|
FAM217B
|
family with sequence similarity 217 member B |
| chr6_+_11537738 | 5.82 |
ENST00000379426.2
|
TMEM170B
|
transmembrane protein 170B |
| chr3_+_15427551 | 5.77 |
ENST00000396842.7
|
EAF1
|
ELL associated factor 1 |
| chr8_-_33567118 | 5.70 |
ENST00000256257.2
|
RNF122
|
ring finger protein 122 |
| chr12_-_122266425 | 5.65 |
ENST00000643696.1
ENST00000267199.9 |
VPS33A
|
VPS33A core subunit of CORVET and HOPS complexes |
| chr7_+_139231225 | 5.54 |
ENST00000473989.8
|
UBN2
|
ubinuclein 2 |
| chr4_+_40056790 | 5.39 |
ENST00000261435.11
ENST00000515550.1 |
N4BP2
|
NEDD4 binding protein 2 |
| chr7_+_66628864 | 5.33 |
ENST00000639828.2
ENST00000275532.8 ENST00000640385.1 |
KCTD7
|
potassium channel tetramerization domain containing 7 |
| chr8_+_57994455 | 5.25 |
ENST00000361488.7
|
FAM110B
|
family with sequence similarity 110 member B |
| chr3_-_56468346 | 5.22 |
ENST00000288221.11
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2 |
| chr1_-_207051202 | 5.16 |
ENST00000315927.9
|
YOD1
|
YOD1 deubiquitinase |
| chr11_-_45665578 | 5.15 |
ENST00000308064.7
|
CHST1
|
carbohydrate sulfotransferase 1 |
| chr4_-_36244438 | 5.14 |
ENST00000303965.9
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr8_-_19013693 | 5.11 |
ENST00000327040.13
|
PSD3
|
pleckstrin and Sec7 domain containing 3 |
| chr3_-_50567646 | 5.09 |
ENST00000426034.5
ENST00000441239.5 |
C3orf18
|
chromosome 3 open reading frame 18 |
| chr3_+_49554436 | 5.08 |
ENST00000296452.5
|
BSN
|
bassoon presynaptic cytomatrix protein |
| chr22_+_39994926 | 5.06 |
ENST00000333407.11
|
FAM83F
|
family with sequence similarity 83 member F |
| chr4_+_7043315 | 5.02 |
ENST00000310074.8
ENST00000512388.1 |
TADA2B
|
transcriptional adaptor 2B |
| chr9_-_23821275 | 5.00 |
ENST00000380110.8
|
ELAVL2
|
ELAV like RNA binding protein 2 |
| chr2_-_16665816 | 5.00 |
ENST00000406434.5
ENST00000381323.7 |
CYRIA
|
CYFIP related Rac1 interactor A |
| chr2_+_181457342 | 4.95 |
ENST00000397033.7
ENST00000233573.6 |
ITGA4
|
integrin subunit alpha 4 |
| chr6_-_136792466 | 4.94 |
ENST00000359015.5
|
MAP3K5
|
mitogen-activated protein kinase kinase kinase 5 |
| chr14_-_99272184 | 4.91 |
ENST00000357195.8
|
BCL11B
|
BAF chromatin remodeling complex subunit BCL11B |
| chr8_-_65842051 | 4.89 |
ENST00000401827.8
|
PDE7A
|
phosphodiesterase 7A |
| chr6_+_107490103 | 4.89 |
ENST00000317357.10
|
SOBP
|
sine oculis binding protein homolog |
| chr18_+_46334007 | 4.82 |
ENST00000269439.12
ENST00000590330.1 |
RNF165
|
ring finger protein 165 |
| chr6_+_106098933 | 4.80 |
ENST00000369089.3
|
PRDM1
|
PR/SET domain 1 |
| chr7_+_35800932 | 4.78 |
ENST00000635172.1
ENST00000399034.7 ENST00000350320.10 ENST00000435235.6 ENST00000672279.1 ENST00000634600.1 ENST00000635047.1 |
SEPTIN7
|
septin 7 |
| chr16_+_7332839 | 4.78 |
ENST00000355637.9
|
RBFOX1
|
RNA binding fox-1 homolog 1 |
| chr1_-_83999097 | 4.71 |
ENST00000260505.13
ENST00000610996.1 |
TTLL7
|
tubulin tyrosine ligase like 7 |
| chr1_+_99264473 | 4.62 |
ENST00000370185.9
|
PLPPR4
|
phospholipid phosphatase related 4 |
| chr22_-_38844020 | 4.61 |
ENST00000333039.4
|
NPTXR
|
neuronal pentraxin receptor |
| chr2_-_196171565 | 4.58 |
ENST00000263955.9
|
STK17B
|
serine/threonine kinase 17b |
| chr15_+_50908674 | 4.58 |
ENST00000261842.10
ENST00000560508.1 |
AP4E1
|
adaptor related protein complex 4 subunit epsilon 1 |
| chr2_-_70248598 | 4.53 |
ENST00000445587.5
ENST00000433529.7 ENST00000415783.6 |
TIA1
|
TIA1 cytotoxic granule associated RNA binding protein |
| chr12_-_42144823 | 4.52 |
ENST00000398675.8
|
GXYLT1
|
glucoside xylosyltransferase 1 |
| chr6_+_41072939 | 4.50 |
ENST00000341376.11
ENST00000353205.5 |
NFYA
|
nuclear transcription factor Y subunit alpha |
| chr3_-_185498964 | 4.46 |
ENST00000296254.3
|
TMEM41A
|
transmembrane protein 41A |
| chr1_-_6180265 | 4.39 |
ENST00000262450.8
|
CHD5
|
chromodomain helicase DNA binding protein 5 |
| chr15_-_50686768 | 4.39 |
ENST00000560955.5
ENST00000646667.1 |
TRPM7
|
transient receptor potential cation channel subfamily M member 7 |
| chr14_-_51096029 | 4.39 |
ENST00000298355.7
|
TRIM9
|
tripartite motif containing 9 |
| chr4_+_47031551 | 4.36 |
ENST00000295454.8
|
GABRB1
|
gamma-aminobutyric acid type A receptor subunit beta1 |
| chr11_-_117098415 | 4.33 |
ENST00000445177.6
ENST00000375300.6 ENST00000446921.6 |
SIK3
|
SIK family kinase 3 |
| chr16_+_56191476 | 4.32 |
ENST00000262493.12
|
GNAO1
|
G protein subunit alpha o1 |
| chr2_+_172735912 | 4.31 |
ENST00000409036.5
|
RAPGEF4
|
Rap guanine nucleotide exchange factor 4 |
| chr3_-_48662877 | 4.28 |
ENST00000164024.5
|
CELSR3
|
cadherin EGF LAG seven-pass G-type receptor 3 |
| chr2_-_135530561 | 4.26 |
ENST00000536680.5
ENST00000401392.5 |
ZRANB3
|
zinc finger RANBP2-type containing 3 |
| chr2_-_38377256 | 4.23 |
ENST00000443098.5
ENST00000449130.5 ENST00000651368.1 ENST00000378954.9 ENST00000419554.6 ENST00000451483.1 ENST00000406122.5 |
ATL2
|
atlastin GTPase 2 |
| chr19_+_12791470 | 4.18 |
ENST00000302754.6
|
JUNB
|
JunB proto-oncogene, AP-1 transcription factor subunit |
| chr1_+_50108856 | 4.12 |
ENST00000650764.1
ENST00000494555.2 ENST00000371824.7 ENST00000371823.8 ENST00000652693.1 |
ELAVL4
|
ELAV like RNA binding protein 4 |
| chr16_-_46831134 | 4.12 |
ENST00000394806.6
ENST00000285697.9 |
C16orf87
|
chromosome 16 open reading frame 87 |
| chr10_+_93758063 | 4.11 |
ENST00000627699.1
ENST00000371413.4 |
LGI1
|
leucine rich glioma inactivated 1 |
| chrX_-_54357993 | 4.09 |
ENST00000375169.7
ENST00000354646.6 |
WNK3
|
WNK lysine deficient protein kinase 3 |
| chr1_-_109041986 | 4.09 |
ENST00000400794.7
ENST00000528747.1 ENST00000361054.7 |
WDR47
|
WD repeat domain 47 |
| chr5_-_160312524 | 4.08 |
ENST00000520748.1
ENST00000257536.13 ENST00000393977.7 |
CCNJL
|
cyclin J like |
| chr6_+_36442985 | 4.08 |
ENST00000373731.7
ENST00000483557.5 ENST00000498267.5 ENST00000449081.6 ENST00000460983.1 |
KCTD20
|
potassium channel tetramerization domain containing 20 |
| chr7_-_31340678 | 4.06 |
ENST00000297142.4
|
NEUROD6
|
neuronal differentiation 6 |
| chr15_+_26867047 | 4.05 |
ENST00000335625.10
ENST00000555182.5 ENST00000400081.7 |
GABRA5
|
gamma-aminobutyric acid type A receptor subunit alpha5 |
| chr16_+_22206255 | 4.03 |
ENST00000263026.10
|
EEF2K
|
eukaryotic elongation factor 2 kinase |
| chr6_+_391743 | 4.03 |
ENST00000380956.9
|
IRF4
|
interferon regulatory factor 4 |
| chr10_-_74150781 | 4.01 |
ENST00000355264.9
ENST00000372745.1 |
AP3M1
|
adaptor related protein complex 3 subunit mu 1 |
| chr19_-_18522051 | 4.00 |
ENST00000262809.9
|
ELL
|
elongation factor for RNA polymerase II |
| chr3_-_187745460 | 4.00 |
ENST00000406870.7
|
BCL6
|
BCL6 transcription repressor |
| chr17_+_76737387 | 3.98 |
ENST00000590393.1
ENST00000355954.7 ENST00000586689.5 ENST00000587661.5 ENST00000593181.5 ENST00000336509.8 |
MFSD11
|
major facilitator superfamily domain containing 11 |
| chr1_+_212858267 | 3.97 |
ENST00000366971.9
|
FLVCR1
|
FLVCR heme transporter 1 |
| chr7_+_87628355 | 3.93 |
ENST00000338056.7
ENST00000493037.5 |
RUNDC3B
|
RUN domain containing 3B |
| chr17_-_73644435 | 3.90 |
ENST00000392650.8
|
SDK2
|
sidekick cell adhesion molecule 2 |
| chr9_-_133121228 | 3.81 |
ENST00000372050.8
|
RALGDS
|
ral guanine nucleotide dissociation stimulator |
| chr14_-_44961889 | 3.77 |
ENST00000579157.1
ENST00000396128.9 ENST00000556500.1 |
KLHL28
|
kelch like family member 28 |
| chr1_+_180632001 | 3.74 |
ENST00000367590.9
ENST00000367589.3 |
XPR1
|
xenotropic and polytropic retrovirus receptor 1 |
| chr2_-_25252251 | 3.72 |
ENST00000380746.8
ENST00000402667.1 |
DNMT3A
|
DNA methyltransferase 3 alpha |
| chr12_-_49110840 | 3.72 |
ENST00000550137.5
ENST00000267102.13 ENST00000547382.5 |
LMBR1L
|
limb development membrane protein 1 like |
| chrX_+_23334841 | 3.70 |
ENST00000379361.5
|
PTCHD1
|
patched domain containing 1 |
| chr3_+_50236192 | 3.69 |
ENST00000313601.11
|
GNAI2
|
G protein subunit alpha i2 |
| chr6_+_157381133 | 3.64 |
ENST00000414563.6
ENST00000359775.10 |
ZDHHC14
|
zinc finger DHHC-type palmitoyltransferase 14 |
| chr1_-_201023694 | 3.63 |
ENST00000332129.6
ENST00000422435.2 ENST00000461742.7 |
KIF21B
|
kinesin family member 21B |
| chr5_-_95961830 | 3.59 |
ENST00000513343.1
ENST00000237853.9 |
ELL2
|
elongation factor for RNA polymerase II 2 |
| chr1_+_95117324 | 3.58 |
ENST00000370203.9
ENST00000456991.5 |
TLCD4
|
TLC domain containing 4 |
| chr11_-_62727444 | 3.56 |
ENST00000301785.7
|
HNRNPUL2
|
heterogeneous nuclear ribonucleoprotein U like 2 |
| chr8_+_26577843 | 3.56 |
ENST00000311151.9
|
DPYSL2
|
dihydropyrimidinase like 2 |
| chr3_+_119468952 | 3.53 |
ENST00000476573.5
ENST00000295588.9 |
POGLUT1
|
protein O-glucosyltransferase 1 |
| chr1_-_114670018 | 3.53 |
ENST00000393274.6
ENST00000393276.7 |
DENND2C
|
DENN domain containing 2C |
| chr7_-_143362687 | 3.53 |
ENST00000409578.5
ENST00000443739.7 ENST00000409346.5 |
FAM131B
|
family with sequence similarity 131 member B |
| chr2_-_206086057 | 3.53 |
ENST00000403263.6
|
INO80D
|
INO80 complex subunit D |
| chr19_+_19320817 | 3.53 |
ENST00000262815.13
ENST00000609122.5 |
MAU2
|
MAU2 sister chromatid cohesion factor |
| chr12_+_71839707 | 3.51 |
ENST00000482439.6
ENST00000550746.5 ENST00000491063.5 ENST00000319106.12 ENST00000485960.7 |
TBC1D15
|
TBC1 domain family member 15 |
| chr1_+_117606040 | 3.48 |
ENST00000369448.4
|
TENT5C
|
terminal nucleotidyltransferase 5C |
| chr21_-_31732054 | 3.46 |
ENST00000399804.5
ENST00000286835.12 |
SCAF4
|
SR-related CTD associated factor 4 |
| chr13_+_42048645 | 3.46 |
ENST00000337343.9
ENST00000261491.9 ENST00000611224.1 |
DGKH
|
diacylglycerol kinase eta |
| chr9_+_100442271 | 3.46 |
ENST00000502978.1
|
MSANTD3-TMEFF1
|
MSANTD3-TMEFF1 readthrough |
| chr15_-_65286837 | 3.44 |
ENST00000444347.2
ENST00000261888.10 ENST00000649807.2 |
PARP16
|
poly(ADP-ribose) polymerase family member 16 |
| chr5_-_132737518 | 3.44 |
ENST00000403231.6
ENST00000378735.5 ENST00000618515.4 ENST00000378746.8 |
KIF3A
|
kinesin family member 3A |
| chr3_+_94062974 | 3.42 |
ENST00000314622.9
|
NSUN3
|
NOP2/Sun RNA methyltransferase 3 |
| chr11_+_112961402 | 3.41 |
ENST00000613217.4
ENST00000316851.12 ENST00000620046.4 ENST00000531044.5 ENST00000529356.5 |
NCAM1
|
neural cell adhesion molecule 1 |
| chr7_+_87934143 | 3.38 |
ENST00000398204.8
|
ADAM22
|
ADAM metallopeptidase domain 22 |
| chr19_-_344786 | 3.38 |
ENST00000264819.7
|
MIER2
|
MIER family member 2 |
| chr8_-_81112055 | 3.36 |
ENST00000220597.4
|
PAG1
|
phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| chr4_-_119628791 | 3.36 |
ENST00000354960.8
|
PDE5A
|
phosphodiesterase 5A |
| chr5_-_150155828 | 3.35 |
ENST00000261799.9
|
PDGFRB
|
platelet derived growth factor receptor beta |
| chr15_+_68054308 | 3.30 |
ENST00000249636.11
|
PIAS1
|
protein inhibitor of activated STAT 1 |
| chr17_-_65056659 | 3.30 |
ENST00000439174.7
|
GNA13
|
G protein subunit alpha 13 |
| chr4_+_48016764 | 3.28 |
ENST00000295461.10
|
NIPAL1
|
NIPA like domain containing 1 |
| chr12_+_69239560 | 3.28 |
ENST00000435070.7
|
CPSF6
|
cleavage and polyadenylation specific factor 6 |
| chr1_-_1778399 | 3.26 |
ENST00000341426.9
|
NADK
|
NAD kinase |
| chr9_-_76906090 | 3.24 |
ENST00000376718.8
|
PRUNE2
|
prune homolog 2 with BCH domain |
| chr1_-_9129085 | 3.23 |
ENST00000377411.5
|
GPR157
|
G protein-coupled receptor 157 |
| chr2_+_241702027 | 3.20 |
ENST00000313552.11
ENST00000406941.5 |
ING5
|
inhibitor of growth family member 5 |
| chr12_-_103841210 | 3.17 |
ENST00000392876.8
|
NT5DC3
|
5'-nucleotidase domain containing 3 |
| chr17_-_76453142 | 3.17 |
ENST00000319380.12
|
UBE2O
|
ubiquitin conjugating enzyme E2 O |
| chr5_-_73565602 | 3.15 |
ENST00000296785.8
|
ANKRA2
|
ankyrin repeat family A member 2 |
| chr14_+_76761453 | 3.15 |
ENST00000167106.9
|
VASH1
|
vasohibin 1 |
| chr15_-_34336749 | 3.13 |
ENST00000397707.6
ENST00000560611.5 |
SLC12A6
|
solute carrier family 12 member 6 |
| chr17_+_997101 | 3.10 |
ENST00000327158.5
|
TIMM22
|
translocase of inner mitochondrial membrane 22 |
| chr16_+_4847431 | 3.09 |
ENST00000262376.11
|
UBN1
|
ubinuclein 1 |
| chr1_-_169893876 | 3.04 |
ENST00000367771.11
ENST00000367772.8 |
SCYL3
|
SCY1 like pseudokinase 3 |
| chr2_-_25982471 | 3.04 |
ENST00000264712.8
|
KIF3C
|
kinesin family member 3C |
| chr4_-_5893075 | 3.01 |
ENST00000324989.12
|
CRMP1
|
collapsin response mediator protein 1 |
| chr10_+_71319249 | 2.97 |
ENST00000373189.6
ENST00000479577.2 |
SLC29A3
|
solute carrier family 29 member 3 |
| chr10_+_115093331 | 2.95 |
ENST00000609571.5
ENST00000355044.8 ENST00000526946.5 |
ATRNL1
|
attractin like 1 |
| chr3_-_120349294 | 2.93 |
ENST00000295628.4
|
LRRC58
|
leucine rich repeat containing 58 |
| chr15_-_52529050 | 2.93 |
ENST00000399231.7
|
MYO5A
|
myosin VA |
| chr19_-_11481044 | 2.88 |
ENST00000359227.8
|
ELAVL3
|
ELAV like RNA binding protein 3 |
| chr1_-_89126066 | 2.86 |
ENST00000370466.4
|
GBP2
|
guanylate binding protein 2 |
| chr9_-_70414657 | 2.84 |
ENST00000377126.4
|
KLF9
|
Kruppel like factor 9 |
| chr11_+_94543894 | 2.80 |
ENST00000358752.4
|
FUT4
|
fucosyltransferase 4 |
| chr2_+_32063533 | 2.80 |
ENST00000315285.9
|
SPAST
|
spastin |
| chr1_+_22451843 | 2.78 |
ENST00000375647.5
ENST00000404138.5 ENST00000374651.8 ENST00000400239.6 |
ZBTB40
|
zinc finger and BTB domain containing 40 |
| chr14_+_99481395 | 2.76 |
ENST00000389879.9
ENST00000557441.5 ENST00000555049.5 ENST00000555842.1 |
CCNK
|
cyclin K |
| chr10_+_111077021 | 2.76 |
ENST00000280155.4
|
ADRA2A
|
adrenoceptor alpha 2A |
| chr1_-_219928551 | 2.75 |
ENST00000366926.4
|
SLC30A10
|
solute carrier family 30 member 10 |
| chr1_-_151716052 | 2.75 |
ENST00000290585.8
|
CELF3
|
CUGBP Elav-like family member 3 |
| chr7_-_138981307 | 2.75 |
ENST00000440172.5
ENST00000422774.2 |
KIAA1549
|
KIAA1549 |
| chr11_+_46332905 | 2.74 |
ENST00000343674.10
|
DGKZ
|
diacylglycerol kinase zeta |
| chr22_-_50474942 | 2.73 |
ENST00000348911.10
ENST00000380817.8 |
SBF1
|
SET binding factor 1 |
| chr12_+_8082260 | 2.71 |
ENST00000638237.1
ENST00000339754.11 ENST00000639811.1 ENST00000639167.1 ENST00000541948.2 |
NECAP1
|
NECAP endocytosis associated 1 |
| chrX_+_118346072 | 2.71 |
ENST00000371822.9
ENST00000254029.8 ENST00000371825.7 |
WDR44
|
WD repeat domain 44 |
| chr2_+_10043524 | 2.70 |
ENST00000305883.6
|
KLF11
|
Kruppel like factor 11 |
| chr22_+_49853801 | 2.70 |
ENST00000216268.6
|
ZBED4
|
zinc finger BED-type containing 4 |
| chr16_-_2214776 | 2.70 |
ENST00000333503.8
|
PGP
|
phosphoglycolate phosphatase |
| chr21_+_29298890 | 2.68 |
ENST00000286800.8
|
BACH1
|
BTB domain and CNC homolog 1 |
| chr2_-_201071579 | 2.68 |
ENST00000453765.5
ENST00000452799.5 ENST00000446678.5 ENST00000418596.7 ENST00000681958.1 |
FAM126B
|
family with sequence similarity 126 member B |
| chr1_+_70411180 | 2.68 |
ENST00000411986.6
|
CTH
|
cystathionine gamma-lyase |
| chr1_-_114511160 | 2.66 |
ENST00000369543.6
ENST00000358465.7 |
TRIM33
|
tripartite motif containing 33 |
| chr22_+_29073024 | 2.64 |
ENST00000400335.9
|
KREMEN1
|
kringle containing transmembrane protein 1 |
| chr9_-_112333603 | 2.63 |
ENST00000450374.1
ENST00000374257.6 ENST00000374255.6 ENST00000334318.10 |
PTBP3
|
polypyrimidine tract binding protein 3 |
| chr2_-_174634566 | 2.63 |
ENST00000392547.6
|
WIPF1
|
WAS/WASL interacting protein family member 1 |
| chr20_+_49812818 | 2.63 |
ENST00000361573.3
|
SLC9A8
|
solute carrier family 9 member A8 |
| chr7_-_98252117 | 2.62 |
ENST00000420697.1
ENST00000415086.5 ENST00000447648.7 |
TECPR1
|
tectonin beta-propeller repeat containing 1 |
| chr7_-_79453544 | 2.62 |
ENST00000419488.5
|
MAGI2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| chr12_+_62260338 | 2.60 |
ENST00000353364.7
ENST00000549523.5 |
USP15
|
ubiquitin specific peptidase 15 |
| chr20_+_49982969 | 2.58 |
ENST00000244050.3
|
SNAI1
|
snail family transcriptional repressor 1 |
| chr3_+_143119749 | 2.57 |
ENST00000309575.5
|
CHST2
|
carbohydrate sulfotransferase 2 |
| chrX_+_104566193 | 2.57 |
ENST00000372582.6
|
IL1RAPL2
|
interleukin 1 receptor accessory protein like 2 |
| chr19_-_6110463 | 2.56 |
ENST00000587181.1
ENST00000587321.1 ENST00000586806.1 ENST00000303657.10 ENST00000589742.5 ENST00000592546.5 |
RFX2
|
regulatory factor X2 |
| chr10_+_75111595 | 2.55 |
ENST00000671800.1
ENST00000542569.6 ENST00000372687.4 |
SAMD8
|
sterile alpha motif domain containing 8 |
| chr2_-_98936155 | 2.54 |
ENST00000428096.5
ENST00000397899.7 ENST00000420294.1 |
CRACDL
|
CRACD like |
| chrX_-_130903224 | 2.54 |
ENST00000370935.5
|
ENOX2
|
ecto-NOX disulfide-thiol exchanger 2 |
| chr5_-_115262851 | 2.53 |
ENST00000379615.3
ENST00000419445.6 |
PGGT1B
|
protein geranylgeranyltransferase type I subunit beta |
| chr22_+_20917398 | 2.53 |
ENST00000354336.8
|
CRKL
|
CRK like proto-oncogene, adaptor protein |
| chr15_-_34210073 | 2.51 |
ENST00000559515.1
ENST00000560108.5 ENST00000256544.8 ENST00000559462.1 |
KATNBL1
|
katanin regulatory subunit B1 like 1 |
| chr13_+_57631735 | 2.51 |
ENST00000377918.8
|
PCDH17
|
protocadherin 17 |
| chr10_+_124801799 | 2.50 |
ENST00000298492.6
|
ABRAXAS2
|
abraxas 2, BRISC complex subunit |
| chr1_+_174799895 | 2.49 |
ENST00000489615.5
|
RABGAP1L
|
RAB GTPase activating protein 1 like |
| chr2_+_165239388 | 2.44 |
ENST00000424833.5
ENST00000375437.7 ENST00000631182.3 |
SCN2A
|
sodium voltage-gated channel alpha subunit 2 |
| chr16_+_21233672 | 2.43 |
ENST00000311620.7
|
ANKS4B
|
ankyrin repeat and sterile alpha motif domain containing 4B |
| chr1_+_11691688 | 2.42 |
ENST00000294485.6
|
DRAXIN
|
dorsal inhibitory axon guidance protein |
| chr4_-_101347471 | 2.42 |
ENST00000323055.10
ENST00000512215.5 |
PPP3CA
|
protein phosphatase 3 catalytic subunit alpha |
| chr21_-_32771712 | 2.38 |
ENST00000331923.9
|
PAXBP1
|
PAX3 and PAX7 binding protein 1 |
| chr17_-_55421818 | 2.36 |
ENST00000262065.8
ENST00000649377.1 |
MMD
|
monocyte to macrophage differentiation associated |
| chr7_-_130440848 | 2.36 |
ENST00000675803.1
ENST00000223208.10 ENST00000343969.10 ENST00000471201.6 ENST00000675649.1 ENST00000675168.1 ENST00000469826.2 ENST00000334451.6 ENST00000675962.1 ENST00000675563.1 ENST00000480206.2 ENST00000489512.5 ENST00000676243.1 ENST00000674539.1 ENST00000675935.1 |
CEP41
|
centrosomal protein 41 |
| chr8_+_42896883 | 2.34 |
ENST00000307602.9
|
HOOK3
|
hook microtubule tethering protein 3 |
| chr8_+_26383043 | 2.31 |
ENST00000380629.7
|
BNIP3L
|
BCL2 interacting protein 3 like |
| chr2_+_95025700 | 2.29 |
ENST00000309988.9
ENST00000353004.7 ENST00000354078.7 ENST00000349807.3 |
MAL
|
mal, T cell differentiation protein |
| chr1_+_183636065 | 2.28 |
ENST00000304685.8
|
RGL1
|
ral guanine nucleotide dissociation stimulator like 1 |
| chr8_+_28494190 | 2.28 |
ENST00000537916.2
ENST00000240093.8 ENST00000523546.1 |
FZD3
|
frizzled class receptor 3 |
| chr10_-_79445617 | 2.27 |
ENST00000372336.4
|
ZCCHC24
|
zinc finger CCHC-type containing 24 |
| chr3_-_56801939 | 2.27 |
ENST00000296315.8
ENST00000495373.5 |
ARHGEF3
|
Rho guanine nucleotide exchange factor 3 |
| chr9_+_100473140 | 2.26 |
ENST00000374879.5
|
TMEFF1
|
transmembrane protein with EGF like and two follistatin like domains 1 |
| chr1_+_12063285 | 2.26 |
ENST00000263932.7
|
TNFRSF8
|
TNF receptor superfamily member 8 |
| chr1_-_235328147 | 2.25 |
ENST00000264183.9
ENST00000418304.1 ENST00000349213.7 |
ARID4B
|
AT-rich interaction domain 4B |
| chr2_-_166375969 | 2.25 |
ENST00000454569.6
ENST00000409672.5 |
SCN9A
|
sodium voltage-gated channel alpha subunit 9 |
| chr19_+_1753499 | 2.24 |
ENST00000382349.5
|
ONECUT3
|
one cut homeobox 3 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 9.7 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 1.7 | 5.2 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 1.7 | 5.1 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 1.6 | 6.6 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
| 1.6 | 4.9 | GO:0097535 | lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) |
| 1.6 | 4.8 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 1.6 | 4.8 | GO:1990654 | regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654) |
| 1.5 | 4.4 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 1.5 | 4.4 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 1.4 | 4.3 | GO:0036292 | DNA rewinding(GO:0036292) |
| 1.3 | 4.0 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082) |
| 1.2 | 4.9 | GO:0050904 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) diapedesis(GO:0050904) |
| 1.2 | 6.1 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 1.1 | 3.4 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 1.1 | 3.3 | GO:2000591 | positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591) |
| 1.0 | 3.1 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 1.0 | 7.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.0 | 4.0 | GO:1990637 | response to prolactin(GO:1990637) |
| 1.0 | 4.8 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.9 | 2.8 | GO:0051228 | mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230) |
| 0.9 | 4.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.9 | 2.6 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.8 | 4.0 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.8 | 3.1 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.8 | 6.2 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.8 | 2.3 | GO:0045554 | TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 0.7 | 3.6 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.7 | 2.8 | GO:0035625 | negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.7 | 2.7 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 0.6 | 1.9 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.6 | 1.9 | GO:0060374 | mast cell differentiation(GO:0060374) |
| 0.6 | 3.7 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 0.6 | 2.4 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.6 | 10.1 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.6 | 1.8 | GO:1901674 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) positive regulation of response to drug(GO:2001025) |
| 0.6 | 1.2 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.6 | 2.9 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.6 | 5.8 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.6 | 1.1 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
| 0.6 | 2.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.6 | 3.4 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.5 | 1.6 | GO:1901993 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.5 | 7.6 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.5 | 6.5 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.5 | 3.7 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.5 | 1.6 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.5 | 1.5 | GO:0071206 | establishment of protein localization to juxtaparanode region of axon(GO:0071206) |
| 0.5 | 6.6 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.5 | 1.0 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.5 | 2.5 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.5 | 2.5 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 0.5 | 5.9 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.5 | 7.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.5 | 1.5 | GO:0001743 | optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619) |
| 0.5 | 1.5 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.5 | 2.4 | GO:1904970 | brush border assembly(GO:1904970) |
| 0.5 | 3.4 | GO:0032328 | alanine transport(GO:0032328) |
| 0.5 | 4.3 | GO:0034086 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
| 0.5 | 5.7 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
| 0.5 | 1.4 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) |
| 0.5 | 3.2 | GO:0071386 | cellular response to corticosterone stimulus(GO:0071386) |
| 0.4 | 3.1 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.4 | 3.1 | GO:0090210 | regulation of establishment of blood-brain barrier(GO:0090210) |
| 0.4 | 2.6 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.4 | 1.3 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 0.4 | 1.7 | GO:1904382 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.4 | 4.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.4 | 5.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.4 | 4.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.4 | 1.1 | GO:0003099 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.4 | 1.1 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.4 | 7.2 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.4 | 1.5 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.4 | 1.1 | GO:1903296 | regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
| 0.4 | 2.6 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.4 | 1.4 | GO:0061091 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.4 | 1.1 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.4 | 2.8 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.3 | 3.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.3 | 1.0 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 0.3 | 1.3 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.3 | 1.6 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
| 0.3 | 1.6 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.3 | 5.8 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.3 | 2.2 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.3 | 0.6 | GO:0050651 | dermatan sulfate biosynthetic process(GO:0030208) dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
| 0.3 | 2.3 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 0.9 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 0.3 | 0.6 | GO:0097325 | melanocyte proliferation(GO:0097325) |
| 0.3 | 2.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.3 | 1.7 | GO:0014004 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.3 | 1.1 | GO:1900104 | hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069) |
| 0.3 | 1.6 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.3 | 1.3 | GO:0001555 | oocyte growth(GO:0001555) |
| 0.3 | 1.5 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.3 | 7.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.3 | 12.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.2 | 1.2 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.2 | 1.0 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) |
| 0.2 | 0.7 | GO:0060214 | endocardium formation(GO:0060214) |
| 0.2 | 3.5 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.2 | 4.9 | GO:0010663 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.2 | 1.5 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.2 | 4.3 | GO:0021794 | thalamus development(GO:0021794) |
| 0.2 | 0.5 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.2 | 1.4 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.2 | 0.9 | GO:0060029 | convergent extension involved in organogenesis(GO:0060029) |
| 0.2 | 2.3 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.2 | 0.5 | GO:1900114 | positive regulation of histone H3-K9 trimethylation(GO:1900114) |
| 0.2 | 1.9 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.2 | 2.8 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.2 | 3.0 | GO:1901642 | nucleoside transmembrane transport(GO:1901642) |
| 0.2 | 2.1 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.2 | 2.4 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.2 | 1.0 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.2 | 3.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.2 | 2.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.2 | 7.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 2.0 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.2 | 1.2 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.2 | 7.7 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.2 | 1.6 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.2 | 2.4 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
| 0.2 | 0.4 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.2 | 1.0 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.2 | 1.0 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.2 | 2.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.2 | 5.3 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.2 | 7.4 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.2 | 3.2 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.2 | 1.7 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.2 | 0.9 | GO:0016078 | tRNA catabolic process(GO:0016078) |
| 0.2 | 1.8 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.2 | 0.9 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 0.2 | 0.7 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.2 | 1.2 | GO:0001767 | establishment of lymphocyte polarity(GO:0001767) |
| 0.2 | 1.5 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.2 | 4.6 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.2 | 2.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.2 | 1.5 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.2 | 0.8 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.2 | 6.3 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.2 | 0.3 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.2 | 7.1 | GO:0042993 | positive regulation of transcription factor import into nucleus(GO:0042993) |
| 0.1 | 1.6 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.1 | 1.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 4.1 | GO:1904037 | positive regulation of epithelial cell apoptotic process(GO:1904037) |
| 0.1 | 0.9 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.1 | 1.9 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.1 | 1.3 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.1 | 1.6 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.1 | 0.3 | GO:0014916 | regulation of lung blood pressure(GO:0014916) |
| 0.1 | 5.0 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
| 0.1 | 0.8 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 2.1 | GO:0035404 | histone-serine phosphorylation(GO:0035404) |
| 0.1 | 1.5 | GO:0034145 | positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
| 0.1 | 2.8 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.1 | 17.8 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.1 | 0.6 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 4.8 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.1 | 3.6 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 2.0 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 2.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.9 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.1 | 1.6 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 4.3 | GO:0014072 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.1 | 2.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.1 | 1.5 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
| 0.1 | 2.2 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 0.2 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.1 | 0.8 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.1 | 0.4 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.1 | 1.5 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 0.1 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.1 | 1.6 | GO:0003159 | morphogenesis of an endothelium(GO:0003159) |
| 0.1 | 4.9 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 1.1 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 0.3 | GO:0090027 | negative regulation of monocyte chemotaxis(GO:0090027) |
| 0.1 | 0.9 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 0.6 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) |
| 0.1 | 1.6 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.1 | 0.7 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.1 | 3.1 | GO:0097576 | vacuole fusion(GO:0097576) |
| 0.1 | 0.7 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 1.5 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.1 | 0.3 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.1 | 4.6 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.1 | 0.8 | GO:1990035 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.1 | 0.4 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.1 | 0.7 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.1 | 0.3 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.1 | 0.4 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.1 | 1.1 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.1 | 0.3 | GO:1902866 | regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866) |
| 0.1 | 2.5 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 3.6 | GO:0043631 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.1 | 0.3 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 1.6 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.1 | 0.8 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 1.2 | GO:0043586 | tongue development(GO:0043586) |
| 0.1 | 5.7 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 1.2 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.1 | 7.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 3.6 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724) |
| 0.1 | 0.7 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.9 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 0.3 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.1 | 0.8 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 0.8 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 1.0 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 1.9 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 0.1 | 1.1 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.1 | 0.2 | GO:2000619 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) protein lipidation involved in autophagosome assembly(GO:0061739) regulation of histone H4-K16 acetylation(GO:2000618) negative regulation of histone H4-K16 acetylation(GO:2000619) |
| 0.1 | 0.4 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.1 | 3.0 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.1 | 1.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 0.9 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 1.5 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
| 0.1 | 2.4 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 1.0 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.1 | 0.7 | GO:0021984 | adenohypophysis development(GO:0021984) |
| 0.1 | 0.2 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 1.4 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 1.6 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.1 | 0.3 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.1 | 1.9 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.1 | 1.0 | GO:0007129 | synapsis(GO:0007129) |
| 0.1 | 0.8 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 1.4 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 6.0 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.2 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.0 | 2.0 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 2.4 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 2.0 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 0.1 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.0 | 1.9 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 3.5 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 1.1 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.0 | 1.5 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 2.0 | GO:0030279 | negative regulation of ossification(GO:0030279) |
| 0.0 | 2.4 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.0 | 0.5 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 0.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 1.0 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.0 | 1.5 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 1.1 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 1.8 | GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway(GO:2001244) |
| 0.0 | 13.0 | GO:0051260 | protein homooligomerization(GO:0051260) |
| 0.0 | 0.1 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.0 | 0.3 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.0 | 0.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 1.2 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.0 | 0.5 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 0.1 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.0 | 0.6 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.2 | GO:0006682 | protein localization to paranode region of axon(GO:0002175) galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 2.0 | GO:0046323 | glucose import(GO:0046323) |
| 0.0 | 1.6 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.0 | 1.6 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.4 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.0 | 0.6 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.0 | 0.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.0 | 1.3 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.8 | GO:0010863 | positive regulation of phospholipase C activity(GO:0010863) |
| 0.0 | 0.6 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.1 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.0 | 0.5 | GO:0002209 | behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) |
| 0.0 | 0.3 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.8 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.0 | 0.9 | GO:0046427 | positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894) |
| 0.0 | 1.0 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.8 | GO:0033173 | calcineurin-NFAT signaling cascade(GO:0033173) |
| 0.0 | 0.4 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.2 | GO:0050951 | sensory perception of temperature stimulus(GO:0050951) |
| 0.0 | 0.2 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.8 | GO:0048477 | oogenesis(GO:0048477) |
| 0.0 | 0.6 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.6 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 10.0 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 0.6 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.0 | 0.2 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.7 | GO:0019674 | NAD metabolic process(GO:0019674) |
| 0.0 | 0.3 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.5 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 7.4 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 1.7 | 5.1 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 1.2 | 4.9 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 1.2 | 3.5 | GO:0032116 | SMC loading complex(GO:0032116) |
| 1.1 | 3.4 | GO:0016939 | kinesin II complex(GO:0016939) |
| 1.0 | 4.0 | GO:0035363 | histone locus body(GO:0035363) |
| 1.0 | 4.9 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.8 | 2.5 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 0.8 | 3.2 | GO:1990393 | 3M complex(GO:1990393) |
| 0.7 | 2.8 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 0.7 | 9.8 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.6 | 4.5 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.6 | 8.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.6 | 4.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.5 | 2.1 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.5 | 4.2 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.5 | 3.1 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.4 | 5.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.4 | 1.3 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.4 | 10.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.4 | 4.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.4 | 6.7 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.4 | 0.4 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.4 | 4.4 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.4 | 10.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.4 | 3.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.3 | 1.7 | GO:0044308 | axonal spine(GO:0044308) |
| 0.3 | 1.0 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.3 | 0.9 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.3 | 2.5 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.3 | 1.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 1.1 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 0.3 | 3.7 | GO:0001741 | XY body(GO:0001741) |
| 0.3 | 2.8 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 1.0 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.2 | 0.7 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.2 | 1.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.2 | 8.4 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.2 | 2.6 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 1.5 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.2 | 1.1 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.2 | 2.4 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.2 | 4.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 8.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 1.0 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.2 | 7.2 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.2 | 0.9 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.2 | 0.6 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.2 | 6.7 | GO:0043235 | receptor complex(GO:0043235) |
| 0.1 | 2.0 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.1 | 8.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 2.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 2.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 7.7 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 6.0 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.7 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 1.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.4 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.1 | 2.7 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.1 | 1.2 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 0.7 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.1 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.1 | 1.3 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 0.1 | 2.9 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 1.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 8.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 1.0 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 3.4 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 5.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.8 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 1.9 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 0.8 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 1.0 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 1.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.6 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 1.6 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 11.0 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.1 | 2.3 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.1 | 4.1 | GO:0005657 | replication fork(GO:0005657) |
| 0.1 | 0.8 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 4.3 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 0.6 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.1 | 1.7 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 2.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 1.5 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 0.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.1 | 0.7 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 2.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.6 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 4.7 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.6 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 3.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.2 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.0 | 3.9 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.3 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 4.0 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.2 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 2.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.7 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 7.6 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 1.2 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 2.9 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 2.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 2.9 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 2.5 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 0.1 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 0.2 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 5.2 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 3.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.3 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.5 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.7 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.2 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 69.7 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.8 | GO:0005581 | collagen trimer(GO:0005581) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 7.2 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 1.7 | 5.2 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 1.6 | 6.4 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 1.6 | 6.3 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 1.3 | 5.4 | GO:0051734 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 1.3 | 8.1 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 1.2 | 4.9 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 1.2 | 3.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 1.1 | 3.3 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 1.1 | 3.3 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 1.1 | 7.7 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 1.1 | 4.4 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 1.1 | 6.5 | GO:0016900 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 1.0 | 3.9 | GO:0051380 | norepinephrine binding(GO:0051380) |
| 0.9 | 4.7 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.9 | 3.7 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.9 | 7.4 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.9 | 2.7 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.9 | 2.6 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.8 | 2.5 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 0.8 | 7.1 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.7 | 2.1 | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 0.7 | 3.4 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.6 | 3.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.6 | 4.9 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.6 | 7.2 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.6 | 10.1 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.6 | 1.8 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.6 | 3.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.5 | 1.6 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.5 | 2.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.5 | 2.6 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.5 | 4.0 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.5 | 1.5 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.5 | 1.5 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.5 | 1.9 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.5 | 4.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.4 | 1.3 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 0.4 | 1.3 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.4 | 7.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.4 | 8.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.4 | 2.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.4 | 1.2 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.4 | 4.3 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.4 | 1.5 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) |
| 0.4 | 4.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.3 | 3.5 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.3 | 4.4 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.3 | 1.0 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 0.3 | 1.3 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.3 | 1.9 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.3 | 1.6 | GO:0004905 | type I interferon receptor activity(GO:0004905) |
| 0.3 | 3.8 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.3 | 1.6 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.3 | 2.8 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.3 | 4.6 | GO:0042577 | phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577) |
| 0.3 | 6.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.3 | 0.8 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.3 | 0.8 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
| 0.3 | 1.6 | GO:0043398 | HLH domain binding(GO:0043398) |
| 0.3 | 1.6 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.3 | 3.1 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.3 | 10.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.3 | 2.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.2 | 4.0 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.2 | 1.2 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.2 | 1.4 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.2 | 3.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.2 | 0.9 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.2 | 3.1 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.2 | 3.4 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.2 | 7.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 7.0 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.2 | 1.8 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.2 | 1.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.2 | 1.0 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.2 | 2.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.2 | 2.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 1.9 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.2 | 0.4 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 3.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 1.6 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.2 | 0.8 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.2 | 9.7 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) |
| 0.2 | 2.3 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.2 | 1.4 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.2 | 3.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.2 | 2.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 1.8 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 3.0 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.1 | 1.0 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 0.7 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 4.4 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.4 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.1 | 2.6 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 4.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 3.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.3 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 1.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 2.9 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 2.1 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 6.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 6.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 3.8 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 5.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 0.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.3 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.1 | 5.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.7 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
| 0.1 | 3.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.5 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.1 | 2.2 | GO:0015929 | hexosaminidase activity(GO:0015929) |
| 0.1 | 2.8 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 1.7 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.1 | 1.9 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 1.3 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 2.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 0.9 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.1 | 0.5 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 0.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 1.9 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.1 | 2.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 2.5 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.1 | 2.9 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.1 | 1.1 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.1 | 1.1 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.1 | 9.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 2.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.9 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 0.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 2.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.6 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 1.6 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 1.2 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 1.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 1.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 1.1 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 1.0 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.1 | 1.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.6 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 1.4 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.1 | 0.2 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.1 | 0.7 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 0.4 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.1 | 2.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 1.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 1.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.4 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 0.5 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.0 | 1.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 1.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.6 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 3.0 | GO:0016279 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.0 | 0.6 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.0 | 2.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.3 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.0 | 0.2 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.0 | 23.6 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 1.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.6 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 6.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.0 | 8.2 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 1.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.6 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.0 | 0.3 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 3.1 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.3 | GO:0016015 | morphogen activity(GO:0016015) BMP binding(GO:0036122) |
| 0.0 | 0.2 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.0 | 2.1 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 2.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 5.6 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 0.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.2 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.1 | GO:0052725 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.0 | 0.3 | GO:0035591 | signaling adaptor activity(GO:0035591) |
| 0.0 | 1.4 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 0.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 1.6 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 1.2 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.1 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.0 | 1.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 1.0 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.7 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 0.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.6 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.0 | 0.6 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 0.4 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 10.5 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.2 | 1.6 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.2 | 4.2 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 3.0 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.2 | 10.7 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.2 | 4.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.2 | 4.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 9.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.2 | 1.0 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.2 | 2.9 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 4.9 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 8.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 5.5 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 10.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 6.3 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 1.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 1.9 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 2.1 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 0.8 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 4.1 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 3.7 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 1.5 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 4.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 2.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 0.8 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 0.3 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 1.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 1.7 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.6 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 3.6 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 2.5 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 0.3 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 1.2 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 2.3 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.4 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 1.1 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 1.0 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 0.8 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.3 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.0 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.8 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.8 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.9 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 4.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 1.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.3 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 12.5 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.3 | 5.8 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.3 | 7.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.3 | 0.9 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.2 | 1.0 | REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE | Genes involved in p53-Dependent G1 DNA Damage Response |
| 0.2 | 5.5 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 5.2 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 0.2 | 4.0 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.2 | 8.4 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 4.7 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.2 | 3.7 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.2 | 6.5 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.2 | 7.1 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.2 | 12.9 | REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.2 | 1.5 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.2 | 2.4 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 2.0 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 3.4 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.1 | 10.3 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 0.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 5.4 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 4.7 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 3.0 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 2.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 1.7 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.1 | 1.6 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 4.0 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 2.5 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 6.7 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 4.0 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.1 | 1.5 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.1 | 3.1 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 1.5 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 2.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 3.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.6 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.1 | 3.5 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.1 | 1.7 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.1 | 2.2 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 2.6 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 0.4 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 1.0 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 0.6 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 2.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 5.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 4.9 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 2.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 3.2 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 3.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 0.6 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.0 | 3.5 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 2.5 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.8 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 1.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 1.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.6 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 1.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.6 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.5 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 1.0 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 1.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 2.8 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.6 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 0.3 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 2.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.5 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.2 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 2.2 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.2 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 6.1 | REACTOME GPCR DOWNSTREAM SIGNALING | Genes involved in GPCR downstream signaling |
| 0.0 | 0.3 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |