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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GUCAGUU

Z-value: 2.65

Motif logo

miRNA associated with seed GUCAGUU

NamemiRBASE accession
MIMAT0000280

Activity profile of GUCAGUU motif

Sorted Z-values of GUCAGUU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUCAGUU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_172750682 5.08 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr4_-_186723776 4.10 ENST00000614102.4
ENST00000441802.7
FAT atypical cadherin 1
chr15_-_52569197 3.70 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr6_-_79078247 3.51 ENST00000275034.5
pleckstrin homology domain interacting protein
chr15_-_49155574 3.50 ENST00000558843.5
ENST00000388901.10
ENST00000542928.5
ENST00000561248.1
ENST00000299259.10
COP9 signalosome subunit 2
chr13_+_28659100 3.49 ENST00000460403.1
ENST00000380842.5
proteasome maturation protein
chr3_-_149971109 3.44 ENST00000239940.11
profilin 2
chrX_+_70290077 3.38 ENST00000374403.4
kinesin family member 4A
chr2_+_222861005 3.11 ENST00000680147.1
ENST00000681009.1
ENST00000679514.1
ENST00000357430.8
acyl-CoA synthetase long chain family member 3
chr12_+_103930332 3.03 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr5_+_146447304 3.01 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
transcription elongation regulator 1
chr1_-_70205531 2.99 ENST00000370952.4
leucine rich repeat containing 40
chr8_-_66613208 2.79 ENST00000522677.8
MYB proto-oncogene like 1
chr2_-_173965356 2.67 ENST00000310015.12
Sp3 transcription factor
chr6_+_116571477 2.67 ENST00000487832.6
ENST00000466444.7
ENST00000518117.5
RWD domain containing 1
chr1_-_109426410 2.66 ENST00000271308.9
proteasome 20S subunit alpha 5
chr2_+_99337364 2.65 ENST00000617677.1
ENST00000289371.11
eukaryotic translation initiation factor 5B
chr3_+_152299392 2.54 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
muscleblind like splicing regulator 1
chr11_-_57335854 2.51 ENST00000529002.2
ENST00000278412.7
structure specific recognition protein 1
chr2_+_28894655 2.47 ENST00000407426.8
WD repeat domain 43
chr2_+_237085875 2.46 ENST00000392008.6
ENST00000409334.5
ENST00000354371.7
COP9 signalosome subunit 8
chr1_-_205750167 2.41 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr1_-_156338226 2.39 ENST00000496684.6
ENST00000368259.6
ENST00000472765.6
ENST00000295688.8
ENST00000533194.5
ENST00000478640.6
chaperonin containing TCP1 subunit 3
chr15_+_76931704 2.36 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
reticulocalbin 2
chr3_-_113746218 2.33 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr17_+_16415553 2.32 ENST00000338560.12
transient receptor potential cation channel subfamily V member 2
chr5_+_87268922 2.22 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RAS p21 protein activator 1
chr6_-_85642922 2.13 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr6_+_154733378 2.12 ENST00000367186.7
ENST00000417268.3
ENST00000367178.8
SR-related CTD associated factor 8
chr8_-_103415085 2.06 ENST00000297578.9
solute carrier family 25 member 32
chr16_+_22297375 2.02 ENST00000615879.4
ENST00000299853.10
ENST00000564209.5
ENST00000565358.5
ENST00000418581.6
ENST00000564883.5
ENST00000359210.8
ENST00000563024.5
RNA polymerase III subunit E
chr4_+_98995709 1.94 ENST00000296411.11
ENST00000625963.1
methionyl aminopeptidase 1
chr12_+_67269328 1.93 ENST00000545606.6
cullin associated and neddylation dissociated 1
chr1_-_77682639 1.87 ENST00000370801.8
ENST00000433749.5
zinc finger ZZ-type containing 3
chr5_+_66144288 1.85 ENST00000334121.11
splicing regulatory glutamic acid and lysine rich protein 1
chr5_+_151771884 1.83 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr1_+_93448155 1.71 ENST00000370253.6
formin binding protein 1 like
chr5_-_132777344 1.70 ENST00000378706.5
septin 8
chr17_+_59707636 1.68 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr8_-_65634138 1.68 ENST00000518908.5
ENST00000276569.8
ENST00000519352.1
armadillo repeat containing 1
chrX_-_134915232 1.66 ENST00000370783.8
motile sperm domain containing 1
chr4_-_73258785 1.63 ENST00000639793.1
ENST00000358602.9
ENST00000330838.10
ENST00000561029.1
ankyrin repeat domain 17
chr1_-_224434750 1.63 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr3_+_150603279 1.58 ENST00000615547.4
ENST00000477889.5
ENST00000471696.6
ENST00000485923.1
selenoprotein T
chr2_-_168247569 1.56 ENST00000355999.5
serine/threonine kinase 39
chr2_+_36355712 1.46 ENST00000280527.7
cysteine rich transmembrane BMP regulator 1
chr3_-_72446623 1.45 ENST00000477973.4
RING1 and YY1 binding protein
chr10_-_100229550 1.43 ENST00000370397.8
component of inhibitor of nuclear factor kappa B kinase complex
chr17_-_8630713 1.36 ENST00000411957.1
ENST00000360416.8
myosin heavy chain 10
chr12_-_118359639 1.35 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr13_-_49792675 1.34 ENST00000261667.8
karyopherin subunit alpha 3
chrX_+_38801451 1.27 ENST00000378474.3
ENST00000336949.7
MID1 interacting protein 1
chr4_+_165327659 1.25 ENST00000507013.5
ENST00000261507.11
ENST00000393766.6
ENST00000504317.1
methylsterol monooxygenase 1
chr12_+_56104527 1.24 ENST00000552766.5
ENST00000303305.11
proliferation-associated 2G4
chr19_+_10871516 1.24 ENST00000327064.9
ENST00000588947.5
coactivator associated arginine methyltransferase 1
chr10_-_119596495 1.23 ENST00000369093.6
TIA1 cytotoxic granule associated RNA binding protein like 1
chr16_-_20900319 1.21 ENST00000564349.5
ENST00000324344.9
ERI1 exoribonuclease family member 2
defective in cullin neddylation 1 domain containing 3
chr2_-_33599269 1.19 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
family with sequence similarity 98 member A
chrX_-_13938618 1.19 ENST00000454189.6
glycoprotein M6B
chr12_+_70243412 1.17 ENST00000550160.5
ENST00000551132.5
ENST00000552915.5
ENST00000550641.6
ENST00000229195.8
ENST00000552483.5
CCR4-NOT transcription complex subunit 2
chr2_+_158456939 1.15 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
plakophilin 4
chr17_-_32342132 1.14 ENST00000577809.6
ENST00000225805.8
chromosome 17 open reading frame 75
chr21_+_29024629 1.13 ENST00000399975.7
ubiquitin specific peptidase 16
chr12_+_50085325 1.11 ENST00000551966.5
ENST00000550477.5
ENST00000394963.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr9_+_124862098 1.08 ENST00000353214.6
actin related protein 2/3 complex subunit 5 like
chr2_-_69387188 1.07 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr12_+_121400041 1.05 ENST00000361234.9
ENST00000613529.4
ring finger protein 34
chr8_+_96493803 0.98 ENST00000518385.5
ENST00000302190.9
syndecan 2
chr11_-_95924067 0.96 ENST00000676027.1
ENST00000675489.1
ENST00000409459.5
ENST00000676261.1
ENST00000352297.11
ENST00000346299.10
ENST00000676272.1
ENST00000393223.8
ENST00000675022.1
ENST00000675362.1
ENST00000675174.1
ENST00000674989.1
ENST00000675848.1
ENST00000675652.1
ENST00000481642.6
myotubularin related protein 2
chr8_-_101205561 0.95 ENST00000519744.5
ENST00000311212.9
ENST00000521272.5
ENST00000519882.5
zinc finger protein 706
chr1_+_84078043 0.91 ENST00000370689.6
ENST00000370688.7
protein kinase cAMP-activated catalytic subunit beta
chr9_+_37422673 0.91 ENST00000318158.11
ENST00000607784.1
glyoxylate and hydroxypyruvate reductase
chrX_+_119574554 0.89 ENST00000371558.7
ENST00000630695.2
ENST00000631185.2
ubiquitin conjugating enzyme E2 A
chr11_-_31811314 0.89 ENST00000640368.2
ENST00000379123.10
ENST00000379115.9
ENST00000419022.6
ENST00000643871.1
ENST00000640610.1
ENST00000639034.2
paired box 6
chr3_+_112990956 0.85 ENST00000383678.8
ENST00000383677.7
ENST00000619116.4
GTP binding protein 8 (putative)
chr12_+_111405861 0.84 ENST00000341259.7
SH2B adaptor protein 3
chr12_-_89656051 0.81 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr13_+_97434154 0.73 ENST00000245304.5
RAP2A, member of RAS oncogene family
chr16_+_67846917 0.72 ENST00000219169.9
ENST00000567105.5
nuclear transport factor 2
chr1_+_244051275 0.70 ENST00000358704.4
zinc finger and BTB domain containing 18
chr5_+_140114085 0.70 ENST00000331327.5
purine rich element binding protein A
chr13_-_75482151 0.70 ENST00000377636.8
TBC1 domain family member 4
chr5_+_72107453 0.68 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr4_-_89837106 0.66 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
synuclein alpha
chr6_+_4889992 0.62 ENST00000343762.5
chromodomain Y like
chr7_-_105388881 0.60 ENST00000460391.5
ENST00000393651.8
SRSF protein kinase 2
chr3_+_147409357 0.57 ENST00000282928.5
Zic family member 1
chr1_-_107965009 0.56 ENST00000527011.5
ENST00000370056.9
vav guanine nucleotide exchange factor 3
chr17_+_57085092 0.56 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr12_+_75480745 0.56 ENST00000266659.8
GLI pathogenesis related 1
chr20_-_33686371 0.56 ENST00000343380.6
E2F transcription factor 1
chr14_-_77616630 0.54 ENST00000216484.7
serine palmitoyltransferase long chain base subunit 2
chr4_-_139177185 0.54 ENST00000394235.6
E74 like ETS transcription factor 2
chr20_-_35411963 0.53 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chr1_+_26695993 0.53 ENST00000324856.13
ENST00000637465.1
AT-rich interaction domain 1A
chr5_-_43313403 0.53 ENST00000325110.11
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr1_+_65264694 0.52 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr16_-_73048104 0.51 ENST00000268489.10
zinc finger homeobox 3
chr8_-_104588998 0.50 ENST00000424843.6
LDL receptor related protein 12
chr22_-_30246739 0.49 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr9_-_97039102 0.49 ENST00000538255.6
ENST00000680221.1
ENST00000681737.1
ENST00000259470.6
ENST00000681927.1
cathepsin V
chr1_-_38873322 0.47 ENST00000397572.5
ENST00000494695.4
MYC binding protein
chr13_+_32586443 0.47 ENST00000315596.15
PDS5 cohesin associated factor B
chr11_-_62679055 0.46 ENST00000294119.6
ENST00000529640.5
ENST00000301935.10
ENST00000534176.1
ENST00000616865.4
UBX domain protein 1
chr1_-_9823953 0.43 ENST00000377298.9
ENST00000361311.4
calsyntenin 1
chr15_-_49046427 0.42 ENST00000261847.7
ENST00000559471.6
ENST00000380927.6
ENST00000559424.1
SECIS binding protein 2 like
chrX_-_119693150 0.39 ENST00000394610.7
septin 6
chr12_-_54280087 0.38 ENST00000209875.9
chromobox 5
chr17_+_32350132 0.36 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207
chr6_+_33620329 0.36 ENST00000374316.9
inositol 1,4,5-trisphosphate receptor type 3
chr19_+_48872412 0.34 ENST00000200453.6
protein phosphatase 1 regulatory subunit 15A
chr3_+_10141763 0.32 ENST00000256474.3
ENST00000345392.2
von Hippel-Lindau tumor suppressor
chr1_-_153963505 0.31 ENST00000356205.9
ENST00000537590.5
solute carrier family 39 member 1
chr19_+_34254543 0.31 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
granule associated Rac and RHOG effector 1
chr7_-_19117625 0.29 ENST00000242261.6
twist family bHLH transcription factor 1
chr4_-_39977836 0.28 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr13_-_44576319 0.27 ENST00000458659.3
TSC22 domain family member 1
chr9_-_14314067 0.27 ENST00000397575.7
nuclear factor I B
chr8_-_28386417 0.25 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr6_-_34392627 0.22 ENST00000607016.2
nudix hydrolase 3
chr15_+_63189554 0.21 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr12_-_96400365 0.19 ENST00000261211.8
ENST00000543119.6
cyclin dependent kinase 17
chr1_+_35931076 0.19 ENST00000397828.3
ENST00000373191.9
argonaute RISC catalytic component 3
chr6_-_98947911 0.18 ENST00000369244.7
ENST00000229971.2
F-box and leucine rich repeat protein 4
chr1_+_96721762 0.14 ENST00000675735.1
ENST00000609116.5
ENST00000674951.1
ENST00000426398.3
ENST00000370197.5
ENST00000370198.5
polypyrimidine tract binding protein 2
chr9_+_130579556 0.14 ENST00000319725.10
far upstream element binding protein 3
chr1_-_23980308 0.13 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
serine and arginine rich splicing factor 10
chr17_+_59893046 0.11 ENST00000393021.7
ENST00000225577.9
ENST00000443572.6
ENST00000406116.7
ribosomal protein S6 kinase B1
chr14_+_79279403 0.11 ENST00000281127.11
neurexin 3
chr20_-_32207708 0.10 ENST00000246229.5
PLAG1 like zinc finger 2
chr1_-_111449209 0.10 ENST00000235090.10
WD repeat domain 77
chrX_+_77910656 0.09 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr1_+_247416149 0.09 ENST00000366497.6
ENST00000391828.8
NLR family pyrin domain containing 3
chr4_+_2469068 0.08 ENST00000541204.5
ENST00000502316.5
ENST00000507247.5
ENST00000509258.5
ENST00000314289.13
ENST00000511859.5
ring finger protein 4
chr19_-_45973863 0.07 ENST00000263257.6
NOVA alternative splicing regulator 2
chr6_+_68635273 0.07 ENST00000370598.6
adhesion G protein-coupled receptor B3
chr8_-_19013693 0.03 ENST00000327040.13
pleckstrin and Sec7 domain containing 3
chr12_-_124863783 0.01 ENST00000546215.5
ENST00000415380.6
ENST00000545493.1
ENST00000261693.11
ENST00000680596.1
scavenger receptor class B member 1
chr4_+_47485268 0.01 ENST00000273859.8
ENST00000504445.1
ATPase phospholipid transporting 10D (putative)
chrX_+_101550537 0.01 ENST00000372829.8
armadillo repeat containing X-linked 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.8 2.4 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.8 3.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.5 1.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.5 2.1 GO:0051182 coenzyme transport(GO:0051182)
0.5 0.5 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.5 1.4 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.4 1.3 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.4 1.2 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.4 6.0 GO:0000338 protein deneddylation(GO:0000338)
0.3 1.0 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.3 5.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 2.7 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.3 1.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 2.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.3 3.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 1.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 3.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 3.5 GO:0043248 proteasome assembly(GO:0043248)
0.2 1.9 GO:0010265 SCF complex assembly(GO:0010265)
0.2 3.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 1.4 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.2 3.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 2.4 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 2.0 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 1.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 2.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.0 GO:0008218 bioluminescence(GO:0008218)
0.2 0.5 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 2.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 1.8 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.9 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.5 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.5 GO:1990834 response to odorant(GO:1990834)
0.1 1.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.3 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 1.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 1.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 1.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 1.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.9 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.9 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 1.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 2.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 2.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 1.7 GO:0007566 embryo implantation(GO:0007566)
0.0 2.7 GO:0010972 regulation of cellular amino acid metabolic process(GO:0006521) negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 2.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 1.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 2.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.2 GO:0017145 stem cell division(GO:0017145)
0.0 2.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.6 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 1.4 GO:0010324 membrane invagination(GO:0010324)
0.0 2.0 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0097149 centralspindlin complex(GO:0097149)
0.4 2.3 GO:0032584 growth cone membrane(GO:0032584)
0.3 2.3 GO:0031415 NatA complex(GO:0031415)
0.3 1.4 GO:0097513 myosin II filament(GO:0097513)
0.2 2.1 GO:0097452 GAIT complex(GO:0097452)
0.2 2.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 3.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 0.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 2.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 2.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 6.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 5.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 5.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.7 GO:0005844 polysome(GO:0005844)
0.1 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 3.1 GO:0005811 lipid particle(GO:0005811)
0.0 3.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 3.4 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 7.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.2 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 5.3 GO:0000785 chromatin(GO:0000785)
0.0 0.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.6 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 1.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.5 1.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.4 1.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.3 3.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.1 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.2 2.8 GO:0046790 virion binding(GO:0046790)
0.2 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 2.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 2.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 3.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 3.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 2.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 2.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 3.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 3.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 2.1 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 2.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0052843 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 1.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 5.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 2.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 4.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 2.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.8 PID E2F PATHWAY E2F transcription factor network
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 1.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 3.4 REACTOME KINESINS Genes involved in Kinesins
0.1 3.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 5.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 2.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 3.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 2.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.6 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha