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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GUGCAAA

Z-value: 0.84

Motif logo

miRNA associated with seed GUGCAAA

NamemiRBASE accession
MIMAT0000073
MIMAT0000074

Activity profile of GUGCAAA motif

Sorted Z-values of GUGCAAA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUGCAAA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_137499293 20.53 ENST00000510689.5
ENST00000394945.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
chr15_-_73633310 18.44 ENST00000345330.9
neuroplastin
chr1_+_51236252 18.41 ENST00000242719.4
ring finger protein 11
chr9_-_136050502 17.56 ENST00000371753.5
NACC family member 2
chr14_-_59630582 16.52 ENST00000395090.5
reticulon 1
chr6_+_121435595 16.30 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr14_+_90397019 16.11 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
calmodulin 1
chrX_+_135985416 15.15 ENST00000370698.7
ENST00000627534.2
ENST00000370695.8
ENST00000630721.3
ENST00000678163.1
solute carrier family 9 member A6
chr12_+_78864768 14.10 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr15_-_34101807 12.26 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
ER membrane protein complex subunit 7
chr15_-_52569197 12.03 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr1_+_236395394 11.20 ENST00000359362.6
EDAR associated death domain
chr6_-_134318097 10.65 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr22_-_35840218 10.56 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr20_-_37527723 10.52 ENST00000397135.1
ENST00000397137.5
BLCAP apoptosis inducing factor
chr8_+_131904071 10.52 ENST00000254624.10
ENST00000522709.5
EFR3 homolog A
chr6_-_16761447 10.32 ENST00000244769.8
ENST00000436367.6
ataxin 1
chr15_+_52019206 9.66 ENST00000681888.1
ENST00000261845.7
ENST00000680066.1
ENST00000680777.1
ENST00000680652.1
mitogen-activated protein kinase 6
chr9_-_90642791 9.39 ENST00000375765.5
ENST00000636786.1
DIRAS family GTPase 2
chr20_+_19758245 9.28 ENST00000255006.12
Ras and Rab interactor 2
chr5_-_79512794 9.21 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr17_+_59707636 9.20 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr10_-_73414027 9.05 ENST00000372921.10
ENST00000372919.8
annexin A7
chr17_-_1179940 8.99 ENST00000302538.10
ABR activator of RhoGEF and GTPase
chr17_-_64662290 8.97 ENST00000262435.14
SMAD specific E3 ubiquitin protein ligase 2
chr17_+_59619885 8.70 ENST00000269122.8
ENST00000580081.1
ENST00000579456.5
clathrin heavy chain
chr5_-_74640719 8.67 ENST00000302351.9
ENST00000509127.2
ectodermal-neural cortex 1
chr14_-_54489003 8.64 ENST00000554908.5
ENST00000616146.4
glia maturation factor beta
chr11_-_12009082 8.61 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr12_+_55973913 8.34 ENST00000553116.5
RAB5B, member RAS oncogene family
chr1_+_244051275 8.26 ENST00000358704.4
zinc finger and BTB domain containing 18
chr5_+_72107453 7.84 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr2_-_85867641 7.82 ENST00000393808.8
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr20_-_49713842 7.67 ENST00000371711.4
beta-1,4-galactosyltransferase 5
chr2_-_2331225 7.56 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
myelin transcription factor 1 like
chr1_-_92961440 7.54 ENST00000370310.5
ENST00000615519.4
ENST00000613902.4
ENST00000616709.4
divergent protein kinase domain 1A
chr2_+_20447065 7.52 ENST00000272233.6
ras homolog family member B
chr5_+_87268922 7.23 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RAS p21 protein activator 1
chr5_+_96662214 7.15 ENST00000395812.6
calpastatin
chr8_-_109648825 7.15 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr1_+_84078043 7.09 ENST00000370689.6
ENST00000370688.7
protein kinase cAMP-activated catalytic subunit beta
chr14_-_63543328 7.00 ENST00000337537.8
protein phosphatase 2 regulatory subunit B'epsilon
chr13_-_29850605 6.91 ENST00000380680.5
ubiquitin like 3
chr4_+_41360759 6.82 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chr18_-_63422398 6.73 ENST00000238497.10
vacuolar protein sorting 4 homolog B
chr14_+_61695777 6.72 ENST00000323441.10
hypoxia inducible factor 1 subunit alpha
chr12_+_71754834 6.58 ENST00000261263.5
RAB21, member RAS oncogene family
chr15_-_51622798 6.54 ENST00000251076.9
Dmx like 2
chr2_-_224947030 6.49 ENST00000409592.7
dedicator of cytokinesis 10
chr1_-_244451896 6.49 ENST00000366535.4
adenylosuccinate synthase 2
chr11_+_121452291 6.47 ENST00000260197.12
sortilin related receptor 1
chr8_-_102864155 6.46 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr3_-_66500973 6.45 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr19_+_41262480 6.44 ENST00000352456.7
ENST00000595018.5
ENST00000597725.5
heterogeneous nuclear ribonucleoprotein U like 1
chr10_-_117005570 6.41 ENST00000260777.14
ENST00000392903.3
shootin 1
chr2_-_168247569 6.41 ENST00000355999.5
serine/threonine kinase 39
chr10_-_71851239 6.40 ENST00000394936.8
prosaposin
chr18_+_8717371 6.39 ENST00000359865.7
microtubule crosslinking factor 1
chr2_+_230712817 6.33 ENST00000258418.10
calcium binding protein 39
chrX_+_78104229 6.32 ENST00000373316.5
phosphoglycerate kinase 1
chr10_+_61901678 6.26 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr1_-_70205531 6.20 ENST00000370952.4
leucine rich repeat containing 40
chr11_-_45665578 6.19 ENST00000308064.7
carbohydrate sulfotransferase 1
chr15_+_58987652 6.13 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr11_-_117316230 5.97 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr2_+_9206762 5.91 ENST00000315273.4
ENST00000281419.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr9_+_113150991 5.80 ENST00000259392.8
solute carrier family 31 member 2
chr15_-_49046427 5.79 ENST00000261847.7
ENST00000559471.6
ENST00000380927.6
ENST00000559424.1
SECIS binding protein 2 like
chr16_-_46689145 5.74 ENST00000299138.12
VPS35 retromer complex component
chrX_+_119574554 5.71 ENST00000371558.7
ENST00000630695.2
ENST00000631185.2
ubiquitin conjugating enzyme E2 A
chr3_+_130850585 5.71 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr1_+_155859550 5.66 ENST00000368324.5
synaptotagmin 11
chr1_-_51519236 5.65 ENST00000371730.6
ENST00000371733.8
epidermal growth factor receptor pathway substrate 15
chr1_-_211830748 5.63 ENST00000366997.9
lysophosphatidylglycerol acyltransferase 1
chrX_+_38801451 5.59 ENST00000378474.3
ENST00000336949.7
MID1 interacting protein 1
chr7_-_112206380 5.48 ENST00000437633.6
ENST00000428084.6
dedicator of cytokinesis 4
chr1_+_28736927 5.46 ENST00000373812.8
ENST00000541996.5
ENST00000496288.5
YTH N6-methyladenosine RNA binding protein 2
chr16_-_66751591 5.43 ENST00000440564.6
ENST00000443351.6
ENST00000566150.5
ENST00000258198.7
dynein cytoplasmic 1 light intermediate chain 2
chr1_+_160205374 5.42 ENST00000368077.5
ENST00000360472.9
proliferation and apoptosis adaptor protein 15
chr17_-_82648428 5.41 ENST00000392325.9
WD repeat domain 45B
chr22_-_18024513 5.35 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr5_+_140868945 5.35 ENST00000398640.7
protocadherin alpha 11
chr22_-_38872206 5.34 ENST00000407418.8
ENST00000216083.6
chromobox 6
chrX_+_147911943 5.25 ENST00000621453.4
ENST00000218200.12
ENST00000370471.7
ENST00000440235.6
ENST00000370477.5
ENST00000621987.4
FMRP translational regulator 1
chr17_-_75855204 5.18 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WW domain binding protein 2
chr1_+_111619751 5.17 ENST00000433097.5
ENST00000369709.3
RAP1A, member of RAS oncogene family
chr7_-_45921264 5.12 ENST00000613132.5
ENST00000381083.9
ENST00000381086.9
insulin like growth factor binding protein 3
chr18_+_9913979 5.12 ENST00000400000.7
ENST00000340541.4
VAMP associated protein A
chr16_-_46973634 5.09 ENST00000317089.10
DnaJ heat shock protein family (Hsp40) member A2
chr5_+_140841183 5.04 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr13_-_25287457 5.02 ENST00000381801.6
myotubularin related protein 6
chr1_+_236142526 4.80 ENST00000366592.8
G protein-coupled receptor 137B
chr1_-_226737277 4.80 ENST00000272117.7
inositol-trisphosphate 3-kinase B
chr1_+_101237009 4.69 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr1_-_185317234 4.68 ENST00000367498.8
influenza virus NS1A binding protein
chr1_+_7771263 4.65 ENST00000054666.11
vesicle associated membrane protein 3
chr5_+_140875299 4.65 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr1_-_149917826 4.64 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr20_+_1266263 4.51 ENST00000649598.1
ENST00000381867.6
ENST00000381873.7
syntaphilin
chr15_+_40239857 4.43 ENST00000260404.8
p21 (RAC1) activated kinase 6
chr2_-_183038405 4.43 ENST00000361354.9
NCK associated protein 1
chr7_+_12211259 4.40 ENST00000396668.8
ENST00000444443.5
ENST00000396667.7
transmembrane protein 106B
chr9_-_76906090 4.34 ENST00000376718.8
prune homolog 2 with BCH domain
chr4_-_68349981 4.32 ENST00000510746.1
ENST00000355665.7
ENST00000344157.9
YTH domain containing 1
chr10_-_77926724 4.24 ENST00000372391.7
discs large MAGUK scaffold protein 5
chr2_-_160493799 4.21 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr12_-_56688276 4.20 ENST00000262033.11
ENST00000448157.6
ENST00000414274.7
ENST00000456859.2
ENST00000614328.4
prostaglandin E synthase 3
chr5_+_140966466 4.19 ENST00000615316.1
ENST00000289269.7
protocadherin alpha subfamily C, 2
chr17_+_59565598 4.15 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr3_-_12664101 4.11 ENST00000251849.9
ENST00000442415.7
Raf-1 proto-oncogene, serine/threonine kinase
chr3_+_50674896 4.08 ENST00000266037.10
dedicator of cytokinesis 3
chr4_+_165327659 4.08 ENST00000507013.5
ENST00000261507.11
ENST00000393766.6
ENST00000504317.1
methylsterol monooxygenase 1
chr20_+_49046246 4.05 ENST00000396192.7
ENST00000262982.3
chromosome segregation 1 like
chrX_-_34657274 4.03 ENST00000275954.4
transmembrane protein 47
chr3_+_172040554 4.03 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr9_-_36400260 4.02 ENST00000259605.11
ENST00000353739.8
ENST00000611646.4
ring finger protein 38
chr5_-_177462379 4.01 ENST00000512501.1
drebrin 1
chr4_-_75673112 3.97 ENST00000395719.7
ENST00000677489.1
G3BP stress granule assembly factor 2
chr6_-_131951364 3.94 ENST00000367976.4
cellular communication network factor 2
chr1_-_243255170 3.86 ENST00000366542.6
centrosomal protein 170
chr3_-_9249623 3.78 ENST00000383836.8
SLIT-ROBO Rho GTPase activating protein 3
chr5_+_139561308 3.78 ENST00000398733.8
ubiquitin conjugating enzyme E2 D2
chr4_-_70839873 3.77 ENST00000545193.5
ENST00000254799.11
G-rich RNA sequence binding factor 1
chr10_-_96586975 3.77 ENST00000371142.9
transmembrane 9 superfamily member 3
chr3_+_49554436 3.74 ENST00000296452.5
bassoon presynaptic cytomatrix protein
chr10_+_28677487 3.73 ENST00000375533.6
BMP and activin membrane bound inhibitor
chr9_-_14314067 3.65 ENST00000397575.7
nuclear factor I B
chr9_+_107283256 3.64 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr10_+_135067 3.63 ENST00000381591.5
zinc finger MYND-type containing 11
chr8_-_66613208 3.59 ENST00000522677.8
MYB proto-oncogene like 1
chr10_+_93496599 3.59 ENST00000371485.8
centrosomal protein 55
chr5_+_140848360 3.58 ENST00000532602.2
protocadherin alpha 9
chr13_+_34942263 3.54 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr12_-_57430956 3.53 ENST00000347140.7
ENST00000402412.5
R3H domain containing 2
chr2_-_69387188 3.50 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr8_+_6708626 3.50 ENST00000285518.11
1-acylglycerol-3-phosphate O-acyltransferase 5
chr10_+_110007964 3.48 ENST00000277900.12
ENST00000356080.9
adducin 3
chr2_-_65130090 3.48 ENST00000398529.7
ENST00000409751.1
ENST00000409892.5
ENST00000409784.8
RAB1A, member RAS oncogene family
chrX_-_109733249 3.47 ENST00000469796.7
ENST00000672401.1
ENST00000671846.1
acyl-CoA synthetase long chain family member 4
chr4_+_38867789 3.47 ENST00000358869.5
family with sequence similarity 114 member A1
chr5_-_134632769 3.46 ENST00000505758.5
ENST00000439578.5
ENST00000502286.1
ENST00000402673.7
secretion associated Ras related GTPase 1B
chr1_-_77759797 3.46 ENST00000524778.1
ENST00000370794.7
ENST00000370793.5
ENST00000370792.7
ubiquitin specific peptidase 33
chr3_+_186783567 3.45 ENST00000323963.10
ENST00000440191.6
eukaryotic translation initiation factor 4A2
chr22_-_20858740 3.37 ENST00000255882.11
phosphatidylinositol 4-kinase alpha
chr17_+_30378903 3.36 ENST00000225719.9
carboxypeptidase D
chr13_+_97222296 3.29 ENST00000343600.8
ENST00000376673.7
ENST00000679496.1
ENST00000345429.10
muscleblind like splicing regulator 2
chr4_-_5893075 3.28 ENST00000324989.12
collapsin response mediator protein 1
chr22_-_21867610 3.25 ENST00000215832.11
ENST00000398822.7
mitogen-activated protein kinase 1
chr8_+_103298836 3.24 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr20_-_44521989 3.23 ENST00000342374.5
ENST00000255175.5
serine incorporator 3
chrX_-_10677720 3.16 ENST00000453318.6
midline 1
chr2_+_188291661 3.11 ENST00000409843.5
GULP PTB domain containing engulfment adaptor 1
chr7_+_35800932 3.10 ENST00000635172.1
ENST00000399034.7
ENST00000350320.10
ENST00000435235.6
ENST00000672279.1
ENST00000634600.1
ENST00000635047.1
septin 7
chr12_+_56080155 3.08 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr11_+_69641146 3.08 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr12_+_752551 3.07 ENST00000315939.11
ENST00000340908.9
ENST00000535572.5
WNK lysine deficient protein kinase 1
chr13_-_36346319 3.04 ENST00000438666.7
spartin
chr6_+_96015964 3.01 ENST00000302103.6
fucosyltransferase 9
chr12_+_12611839 2.99 ENST00000228865.3
cAMP responsive element binding protein like 2
chr1_+_179025886 2.99 ENST00000263733.5
FAM20B glycosaminoglycan xylosylkinase
chr4_-_170003738 2.96 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr11_-_6683282 2.95 ENST00000532203.1
ENST00000288937.7
mitochondrial ribosomal protein L17
chr14_-_34462223 2.95 ENST00000298130.5
serine palmitoyltransferase small subunit A
chr1_+_160115715 2.93 ENST00000361216.8
ATPase Na+/K+ transporting subunit alpha 2
chr12_-_25250879 2.89 ENST00000256078.10
ENST00000311936.8
ENST00000556131.1
ENST00000557334.5
KRAS proto-oncogene, GTPase
chr5_+_140786136 2.89 ENST00000378133.4
ENST00000504120.4
protocadherin alpha 1
chr2_-_39437264 2.88 ENST00000263881.8
ENST00000341681.9
mitogen-activated protein kinase kinase kinase kinase 3
chr12_+_68610858 2.88 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B, member of RAS oncogene family
chr16_-_85011463 2.85 ENST00000564466.5
ENST00000313732.9
zinc finger DHHC-type palmitoyltransferase 7
chr1_+_27773189 2.83 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr9_+_129111380 2.80 ENST00000347048.8
ENST00000337738.6
ENST00000355007.7
ENST00000393370.7
ENST00000414331.5
protein phosphatase 2 phosphatase activator
chr2_+_62705644 2.80 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EH domain binding protein 1
chr8_+_20197369 2.77 ENST00000276390.7
ENST00000519667.1
ATPase H+ transporting V1 subunit B2
chr1_-_222712428 2.75 ENST00000355727.3
ENST00000340020.11
axin interactor, dorsalization associated
chr4_+_159267737 2.75 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr2_+_134120169 2.74 ENST00000409645.5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr9_+_122941003 2.72 ENST00000373647.9
ENST00000402311.5
RAB GTPase activating protein 1
chr1_-_201469151 2.70 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr2_-_96870034 2.69 ENST00000305476.10
semaphorin 4C
chr8_-_13514821 2.68 ENST00000276297.9
DLC1 Rho GTPase activating protein
chr8_+_58411333 2.63 ENST00000399598.7
UBX domain protein 2B
chr6_+_44270434 2.62 ENST00000451188.7
transmembrane protein 151B
chr20_+_19212624 2.58 ENST00000328041.11
solute carrier family 24 member 3
chr1_+_113929600 2.57 ENST00000369558.5
ENST00000369561.8
homeodomain interacting protein kinase 1
chr15_+_39581068 2.57 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr9_+_2015335 2.53 ENST00000636559.1
ENST00000349721.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr18_+_3451647 2.53 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr12_+_1691011 2.51 ENST00000357103.5
adiponectin receptor 2
chr11_+_123525822 2.51 ENST00000322282.11
ENST00000529750.5
GRAM domain containing 1B
chr5_-_172006817 2.49 ENST00000296933.10
F-box and WD repeat domain containing 11
chr2_-_86337654 2.47 ENST00000165698.9
receptor accessory protein 1
chr8_+_103819244 2.46 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr1_-_153986329 2.45 ENST00000368575.5
RAB13, member RAS oncogene family
chr5_-_132737518 2.45 ENST00000403231.6
ENST00000378735.5
ENST00000618515.4
ENST00000378746.8
kinesin family member 3A
chr2_+_27370496 2.44 ENST00000537606.5
ENST00000233575.7
sorting nexin 17
chrX_+_41334154 2.42 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr8_-_17246846 2.42 ENST00000628418.1
ENST00000361272.9
ENST00000523917.5
CCR4-NOT transcription complex subunit 7
chr1_-_94541746 2.41 ENST00000334047.12
coagulation factor III, tissue factor
chr2_-_171894227 2.41 ENST00000422440.7
solute carrier family 25 member 12
chr11_+_34051722 2.39 ENST00000341394.9
ENST00000389645.7
cell cycle associated protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.2 12.7 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
4.1 16.3 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
2.7 19.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
2.6 7.8 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.5 17.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
2.3 9.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.2 9.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
2.2 6.7 GO:1903722 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) regulation of centriole elongation(GO:1903722)
2.2 9.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.2 8.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.2 6.5 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.2 6.5 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
2.1 6.4 GO:0070650 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
2.0 4.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
1.9 5.7 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154)
1.8 17.9 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.7 5.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
1.7 5.2 GO:1902804 negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.7 8.6 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
1.6 4.7 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.5 10.7 GO:0070294 renal sodium ion absorption(GO:0070294)
1.5 10.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.3 5.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
1.2 3.7 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.2 2.5 GO:1902463 protein localization to cell leading edge(GO:1902463)
1.2 7.1 GO:0097338 response to clozapine(GO:0097338)
1.1 3.4 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
1.1 6.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
1.1 3.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.1 3.2 GO:0019858 cytosine metabolic process(GO:0019858)
1.1 8.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.1 6.4 GO:0048840 otolith development(GO:0048840)
1.0 3.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
1.0 2.9 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
1.0 2.9 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
1.0 5.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.9 5.6 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.9 12.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.9 5.5 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.9 5.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.8 1.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.8 3.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.8 2.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.8 8.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.8 3.9 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.7 2.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.7 2.2 GO:0003162 atrioventricular node development(GO:0003162)
0.7 7.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.7 2.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7 4.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.7 2.8 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.7 4.9 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.7 2.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.7 6.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.6 8.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.6 6.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576)
0.6 1.9 GO:1903279 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.6 1.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.6 2.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.6 6.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.6 4.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.6 1.7 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.6 1.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.5 7.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.5 3.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.5 5.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.5 5.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.5 0.9 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.5 2.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 9.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.4 1.8 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.4 2.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 1.3 GO:0016240 autophagosome docking(GO:0016240)
0.4 28.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.4 6.5 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 3.2 GO:0009597 detection of virus(GO:0009597)
0.4 1.2 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.4 0.8 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.4 6.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 3.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.4 1.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.4 2.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.4 4.6 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.4 13.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.4 1.8 GO:0071233 cellular response to leucine(GO:0071233)
0.4 2.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 3.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 4.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 1.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.7 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.3 3.7 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 2.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.3 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 1.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 5.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 2.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 8.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 1.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 2.4 GO:0042256 mature ribosome assembly(GO:0042256) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 1.8 GO:0090269 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.3 5.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 2.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.3 3.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 1.8 GO:1903895 negative regulation of mRNA cleavage(GO:0031438) negative regulation of IRE1-mediated unfolded protein response(GO:1903895) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.3 6.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.3 1.4 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.3 1.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.3 2.0 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.3 3.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 7.5 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.3 24.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.3 2.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 0.8 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.3 2.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 3.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.3 5.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 7.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3 6.3 GO:0031639 plasminogen activation(GO:0031639)
0.2 4.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 10.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.2 3.0 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 1.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 3.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 3.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 2.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 2.0 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.2 2.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.9 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.2 5.1 GO:0042026 protein refolding(GO:0042026)
0.2 2.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 1.9 GO:0032808 lacrimal gland development(GO:0032808)
0.2 3.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 2.7 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.2 1.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 2.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 0.7 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 3.6 GO:0044803 multi-organism membrane organization(GO:0044803)
0.2 1.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 2.4 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.2 2.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 8.8 GO:0007566 embryo implantation(GO:0007566)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 0.3 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.2 2.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 7.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 2.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.3 GO:0090427 activation of meiosis(GO:0090427)
0.2 4.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.4 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 2.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 2.8 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 5.4 GO:0051642 centrosome localization(GO:0051642)
0.1 0.6 GO:0051006 positive regulation of lipoprotein lipase activity(GO:0051006)
0.1 13.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 3.6 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 4.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 5.5 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.5 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.9 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 3.6 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 1.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 3.1 GO:0003197 endocardial cushion development(GO:0003197)
0.1 14.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.6 GO:0090382 phagosome maturation(GO:0090382)
0.1 2.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 4.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 5.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 1.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 1.0 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 3.8 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 0.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 2.8 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 2.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 2.3 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 11.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 1.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 8.0 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.1 1.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.0 GO:0006183 GTP biosynthetic process(GO:0006183)
0.1 2.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 1.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 1.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.3 GO:2001184 positive regulation of cytokine secretion involved in immune response(GO:0002741) myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 1.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 2.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.8 GO:0016577 histone demethylation(GO:0016577)
0.0 3.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.2 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 3.9 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 2.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 3.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 6.5 GO:0051168 nuclear export(GO:0051168)
0.0 1.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 3.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 2.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 2.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 6.1 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 2.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 2.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.0 GO:0021510 spinal cord development(GO:0021510)
0.0 2.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 6.2 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 1.0 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.0 0.5 GO:0031100 organ regeneration(GO:0031100)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 14.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
2.6 10.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
2.3 11.5 GO:0044308 axonal spine(GO:0044308)
2.2 11.0 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
2.0 6.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
1.9 5.7 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.9 24.1 GO:0060077 inhibitory synapse(GO:0060077)
1.4 12.3 GO:0072546 ER membrane protein complex(GO:0072546)
1.3 6.5 GO:0043291 RAVE complex(GO:0043291)
1.3 9.0 GO:0042584 chromaffin granule membrane(GO:0042584)
1.2 3.7 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
1.1 5.7 GO:0033503 HULC complex(GO:0033503)
0.9 3.6 GO:0071942 XPC complex(GO:0071942)
0.9 16.3 GO:0005922 connexon complex(GO:0005922)
0.9 8.7 GO:0071439 clathrin complex(GO:0071439)
0.8 6.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.8 2.4 GO:0016939 kinesin II complex(GO:0016939)
0.7 10.3 GO:0090543 Flemming body(GO:0090543)
0.7 2.9 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.6 1.3 GO:1903349 omegasome membrane(GO:1903349)
0.5 3.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 17.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.5 17.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5 7.1 GO:0097433 dense body(GO:0097433)
0.4 1.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.3 GO:0000805 X chromosome(GO:0000805)
0.4 3.5 GO:0030891 VCB complex(GO:0030891)
0.4 7.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 7.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 18.3 GO:0033268 node of Ranvier(GO:0033268)
0.4 4.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.4 4.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 4.0 GO:0097427 microtubule bundle(GO:0097427)
0.3 3.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 4.0 GO:0005921 gap junction(GO:0005921)
0.3 6.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 6.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 3.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.3 0.8 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.3 1.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 6.4 GO:0044295 axonal growth cone(GO:0044295)
0.3 7.4 GO:0031143 pseudopodium(GO:0031143)
0.3 2.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 1.2 GO:0016589 NURF complex(GO:0016589)
0.2 21.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 1.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 2.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 14.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 4.8 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.2 3.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 3.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 7.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.9 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 8.2 GO:0043034 costamere(GO:0043034)
0.1 3.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 5.5 GO:0032420 stereocilium(GO:0032420)
0.1 21.2 GO:0055037 recycling endosome(GO:0055037)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 7.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 8.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0001739 sex chromatin(GO:0001739)
0.1 6.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 15.7 GO:0005875 microtubule associated complex(GO:0005875)
0.1 6.7 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 31.4 GO:0005819 spindle(GO:0005819)
0.1 3.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.9 GO:0097443 sorting endosome(GO:0097443)
0.1 13.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 11.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 3.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 2.4 GO:0071564 npBAF complex(GO:0071564)
0.1 2.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 5.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 3.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 4.0 GO:0036126 sperm flagellum(GO:0036126)
0.1 4.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 5.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 9.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 4.6 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204) GAIT complex(GO:0097452)
0.1 19.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 3.8 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 3.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 7.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 6.4 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 4.7 GO:0001726 ruffle(GO:0001726)
0.0 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 8.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 13.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.8 14.1 GO:0030348 syntaxin-3 binding(GO:0030348)
2.7 16.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
2.6 15.6 GO:0034046 poly(G) binding(GO:0034046)
2.1 6.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
2.0 7.8 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.6 7.9 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
1.5 6.1 GO:0032184 SUMO polymer binding(GO:0032184)
1.5 6.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.3 13.4 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.1 8.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.0 2.9 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9 20.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 6.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.9 6.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.9 3.5 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.9 9.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.9 3.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.9 2.6 GO:0070052 collagen V binding(GO:0070052)
0.9 7.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.8 4.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.8 2.5 GO:0055100 adiponectin binding(GO:0055100)
0.8 5.8 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.8 2.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.8 9.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.7 7.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.7 6.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.7 4.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7 2.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.6 5.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.6 2.4 GO:0043273 CTPase activity(GO:0043273)
0.6 7.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6 3.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.5 5.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.5 13.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.5 1.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 9.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.5 2.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.5 1.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.5 3.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 13.6 GO:0004707 MAP kinase activity(GO:0004707)
0.4 2.6 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.4 12.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 1.2 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.4 1.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 34.0 GO:0019003 GDP binding(GO:0019003)
0.4 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 1.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.3 1.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 7.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 3.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.3 3.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 3.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 4.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 8.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 3.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 3.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 17.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 4.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 10.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.3 1.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.3 16.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.3 1.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 4.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 4.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 2.8 GO:0038132 neuregulin binding(GO:0038132)
0.2 5.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) steroid hormone binding(GO:1990239)
0.2 6.9 GO:0001671 ATPase activator activity(GO:0001671)
0.2 4.0 GO:0005522 profilin binding(GO:0005522)
0.2 0.9 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.2 10.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 12.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 15.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 8.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 5.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 6.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 5.7 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.2 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 1.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 6.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 8.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 8.2 GO:0019894 kinesin binding(GO:0019894)
0.2 7.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.2 2.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 3.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.8 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.9 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 2.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 7.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.1 0.9 GO:0000182 rDNA binding(GO:0000182)
0.1 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 2.6 GO:0031005 filamin binding(GO:0031005)
0.1 1.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.8 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 2.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.1 7.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 5.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 29.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 8.0 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 10.4 GO:0044325 ion channel binding(GO:0044325)
0.1 2.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.1 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 3.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 11.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 7.8 GO:0008017 microtubule binding(GO:0008017)
0.0 2.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 9.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 6.5 GO:0003924 GTPase activity(GO:0003924)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 15.3 GO:0003779 actin binding(GO:0003779)
0.0 1.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 13.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.8 GO:0020037 heme binding(GO:0020037)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0017016 Ras GTPase binding(GO:0017016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 20.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 4.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 13.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.3 16.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 17.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 14.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 13.0 PID REELIN PATHWAY Reelin signaling pathway
0.3 10.7 PID INSULIN PATHWAY Insulin Pathway
0.3 16.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 8.3 PID IL3 PATHWAY IL3-mediated signaling events
0.2 6.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 11.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 8.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.2 4.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 9.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 10.7 PID BMP PATHWAY BMP receptor signaling
0.2 6.3 PID ARF6 PATHWAY Arf6 signaling events
0.2 6.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 3.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 6.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 8.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 6.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 8.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.3 PID FOXO PATHWAY FoxO family signaling
0.1 3.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 7.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 3.1 PID P73PATHWAY p73 transcription factor network
0.0 4.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 25.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.8 16.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7 10.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.7 16.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.6 1.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.5 13.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.4 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 5.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.4 12.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4 5.5 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.3 5.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 11.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 2.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 10.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 5.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 6.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 3.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 5.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 6.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 4.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 3.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 8.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 4.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 4.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 5.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 6.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 6.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 6.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 19.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 7.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 13.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 6.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 3.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 6.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.1 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.3 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.1 7.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 5.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.7 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 2.3 REACTOME S PHASE Genes involved in S Phase
0.0 1.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 3.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 4.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing