Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for HBP1

Z-value: 6.49

Motif logo

Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
ENSG00000105856.14 HBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg38_v1_chr7_+_107168961_107169010-0.304.5e-06Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr2_+_74198605 22.79 ENST00000409804.5
ENST00000678340.1
ENST00000679055.1
ENST00000394053.7
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr12_-_52926459 20.08 ENST00000552150.5
keratin 8
chr2_-_10837977 17.30 ENST00000404824.2
protein disulfide isomerase family A member 6
chr1_-_23800402 17.16 ENST00000374497.7
ENST00000425913.5
UDP-galactose-4-epimerase
chr20_-_35284745 17.02 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chrX_+_150983299 15.70 ENST00000325307.12
high mobility group box 3
chr12_-_57752345 15.33 ENST00000551800.5
ENST00000549606.5
ENST00000312990.10
cyclin dependent kinase 4
chr1_-_23800745 14.71 ENST00000617979.5
ENST00000418277.5
UDP-galactose-4-epimerase
chr19_-_42302292 13.71 ENST00000594989.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr11_-_47642519 13.14 ENST00000302503.8
ENST00000530428.1
mitochondrial carrier 2
chrX_+_150983350 12.73 ENST00000455596.5
ENST00000448905.6
high mobility group box 3
chr17_+_51153551 12.68 ENST00000393196.8
ENST00000336097.7
ENST00000480143.5
ENST00000511355.5
ENST00000393193.6
ENST00000376392.10
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
chr2_-_219399981 12.03 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr19_+_34365173 11.91 ENST00000589640.5
ENST00000591204.5
ENST00000589399.6
ENST00000356487.11
glucose-6-phosphate isomerase
chr20_-_35284715 11.62 ENST00000374436.7
ENST00000675032.1
eukaryotic translation initiation factor 6
chr17_+_51153628 11.57 ENST00000555572.1
ENST00000013034.3
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 1
chr19_+_17302854 11.56 ENST00000594999.1
mitochondrial ribosomal protein L34
chr15_-_66356672 11.36 ENST00000261881.9
TIMELESS interacting protein
chr19_-_10587219 11.22 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr22_+_20117734 10.83 ENST00000416427.5
ENST00000421656.5
ENST00000423859.5
ENST00000418705.2
RAN binding protein 1
chr3_+_133805789 10.58 ENST00000678299.1
SRP receptor subunit beta
chr2_-_110473041 10.55 ENST00000632897.1
ENST00000413601.3
LIM zinc finger domain containing 4
chr5_-_140691312 10.54 ENST00000438307.6
ENST00000415192.6
ENST00000509087.2
ENST00000675698.1
ENST00000504156.7
ENST00000457527.6
ENST00000307633.7
ENST00000676327.1
ENST00000675851.1
ENST00000675366.1
ENST00000675204.1
ENST00000507746.7
ENST00000431330.7
histidyl-tRNA synthetase 1
chr11_-_65900375 10.26 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr11_-_46846233 10.14 ENST00000529230.6
ENST00000312055.9
cytoskeleton associated protein 5
chr19_+_34365240 9.89 ENST00000586425.2
glucose-6-phosphate isomerase
chr3_+_100709424 9.79 ENST00000675246.1
ENST00000675692.1
ENST00000675890.1
ENST00000675586.1
ENST00000674645.1
ENST00000675958.1
ENST00000479672.6
ENST00000675420.1
ENST00000674615.1
ENST00000676431.1
ENST00000674758.1
trafficking from ER to golgi regulator
chr11_-_65900413 9.64 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr3_+_100709473 9.48 ENST00000240851.9
ENST00000675243.1
ENST00000676111.1
ENST00000476228.5
ENST00000463568.6
ENST00000676395.1
trafficking from ER to golgi regulator
chr3_+_100709290 9.27 ENST00000675047.1
ENST00000490574.6
ENST00000675543.1
ENST00000676308.1
ENST00000675499.1
trafficking from ER to golgi regulator
chrX_+_71254781 9.11 ENST00000677446.1
non-POU domain containing octamer binding
chr3_+_100709344 9.06 ENST00000418917.7
ENST00000675553.1
trafficking from ER to golgi regulator
chr3_+_100709382 8.87 ENST00000620299.5
trafficking from ER to golgi regulator
chr20_-_34955635 8.81 ENST00000644793.1
ENST00000642498.1
ENST00000646735.1
ENST00000644608.1
ENST00000651619.1
glutathione synthetase
chr5_-_62403506 8.62 ENST00000680062.1
DIMT1 rRNA methyltransferase and ribosome maturation factor
chr7_-_101165558 8.57 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr19_+_38647679 8.43 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr20_-_49713842 8.27 ENST00000371711.4
beta-1,4-galactosyltransferase 5
chr22_+_20117497 8.16 ENST00000331821.7
ENST00000411892.5
RAN binding protein 1
chr1_+_51617079 7.92 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
oxysterol binding protein like 9
chr3_-_146161167 7.74 ENST00000360060.7
ENST00000282903.10
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
chr3_-_165837412 7.24 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr7_+_66075913 6.87 ENST00000362000.10
ENST00000395331.4
ENST00000671817.1
argininosuccinate lyase
chr7_+_66075876 6.81 ENST00000395332.8
argininosuccinate lyase
chr7_+_6577416 6.79 ENST00000405731.7
ENST00000396713.6
ENST00000396707.6
ENST00000335965.11
ENST00000396709.5
ENST00000483589.5
ENST00000396706.2
zinc finger DHHC-type palmitoyltransferase 4
chr7_+_66075811 6.71 ENST00000304874.14
ENST00000673518.1
ENST00000380839.9
argininosuccinate lyase
chr22_-_30246739 6.64 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr21_+_43719095 6.55 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr16_-_82170175 6.50 ENST00000563504.5
ENST00000569021.1
ENST00000258169.9
M-phase phosphoprotein 6
chr11_+_35186820 6.47 ENST00000531110.6
ENST00000525685.6
CD44 molecule (Indian blood group)
chr12_-_89352487 6.46 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr5_-_79514127 6.26 ENST00000334082.11
homer scaffold protein 1
chr19_-_10194898 6.25 ENST00000359526.9
ENST00000679103.1
ENST00000676610.1
ENST00000678804.1
ENST00000679313.1
ENST00000677946.1
DNA methyltransferase 1
chr12_-_89352395 6.09 ENST00000308385.6
dual specificity phosphatase 6
chr9_-_125484490 6.02 ENST00000444226.1
MAPK associated protein 1
chr1_+_65147657 6.02 ENST00000546702.5
adenylate kinase 4
chr2_+_172427573 6.00 ENST00000684293.1
ENST00000409080.6
ENST00000442250.6
integrin subunit alpha 6
chrX_-_23907887 5.92 ENST00000379226.9
apolipoprotein O
chr2_+_172427662 5.88 ENST00000264107.12
ENST00000458358.5
integrin subunit alpha 6
chr19_+_38647614 5.84 ENST00000252699.7
ENST00000424234.7
ENST00000440400.2
actinin alpha 4
chr7_+_141551278 5.69 ENST00000629555.2
ENST00000473247.5
ENST00000648690.1
ENST00000649286.2
ENST00000649914.1
ENST00000648395.1
ENST00000648068.1
ENST00000650547.1
acylglycerol kinase
chr7_+_95485898 5.61 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr22_-_17773976 5.57 ENST00000317361.11
BH3 interacting domain death agonist
chr2_+_206765578 5.52 ENST00000403094.3
ENST00000402774.8
FAST kinase domains 2
chr12_-_123633604 5.52 ENST00000534960.5
ENST00000424014.7
eukaryotic translation initiation factor 2B subunit alpha
chrX_+_51893533 5.49 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr9_+_124862098 5.46 ENST00000353214.6
actin related protein 2/3 complex subunit 5 like
chr9_-_124861940 5.13 ENST00000348462.6
ENST00000629845.1
ribosomal protein L35
chr9_+_33795551 5.12 ENST00000379405.4
serine protease 3
chr3_+_140941901 4.94 ENST00000453248.6
solute carrier family 25 member 36
chr4_-_47463649 4.82 ENST00000381571.6
COMM domain containing 8
chr5_+_96702765 4.77 ENST00000675614.1
ENST00000395813.5
ENST00000675858.1
ENST00000511049.5
ENST00000309190.9
ENST00000510156.5
ENST00000509903.5
ENST00000511782.5
ENST00000504465.5
ENST00000674587.1
calpastatin
chr3_-_15797930 4.76 ENST00000683139.1
ankyrin repeat domain 28
chr19_-_45424364 4.70 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr20_-_1466904 4.70 ENST00000476071.5
NSFL1 cofactor
chrX_+_100820359 4.70 ENST00000415585.6
ENST00000372972.7
ENST00000413437.1
cleavage stimulation factor subunit 2
chr8_+_94641074 4.52 ENST00000423620.6
epithelial splicing regulatory protein 1
chr10_+_13161543 4.47 ENST00000378714.8
ENST00000479669.5
ENST00000484800.6
minichromosome maintenance 10 replication initiation factor
chr8_-_129939694 4.43 ENST00000522250.5
ENST00000522941.5
ENST00000522746.5
ENST00000520204.5
ENST00000519070.5
ENST00000520254.5
ENST00000519824.6
CYFIP related Rac1 interactor B
chr8_-_129939872 4.40 ENST00000519540.5
CYFIP related Rac1 interactor B
chr3_-_197299281 4.40 ENST00000419354.5
ENST00000667104.1
ENST00000658701.1
discs large MAGUK scaffold protein 1
chr7_+_142760398 4.37 ENST00000632998.1
serine protease 2
chr17_-_44066595 4.36 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chr3_+_58306505 4.34 ENST00000461393.7
hydroxyacyl-thioester dehydratase type 2
chr3_-_15798184 4.33 ENST00000624145.3
ankyrin repeat domain 28
chr3_-_197299067 4.30 ENST00000663148.1
discs large MAGUK scaffold protein 1
chr9_-_124861915 4.24 ENST00000373570.8
ribosomal protein L35
chr20_-_1466822 4.21 ENST00000353088.6
ENST00000216879.9
NSFL1 cofactor
chr15_+_57592003 4.14 ENST00000587652.5
ENST00000649429.1
ENST00000380568.7
ENST00000380565.8
GRINL1A complex locus 1
myocardial zonula adherens protein
chr20_+_25195664 4.13 ENST00000354989.9
ENST00000360031.6
ENST00000376652.9
ENST00000439162.5
ENST00000433417.5
ENST00000417467.5
ENST00000433259.6
ENST00000427553.5
ectonucleoside triphosphate diphosphohydrolase 6
chr17_+_77373085 4.05 ENST00000423034.6
septin 9
chr15_+_57591891 4.01 ENST00000267853.10
ENST00000380569.6
myocardial zonula adherens protein
GRINL1A complex locus 1
chrX_+_101408198 4.00 ENST00000316594.6
heterogeneous nuclear ribonucleoprotein H2
chr3_+_158801926 3.93 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chr1_+_23019415 3.66 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
lysine demethylase 1A
chr4_+_121801311 3.63 ENST00000379663.7
ENST00000243498.10
ENST00000509800.5
exosome component 9
chr17_-_1684807 3.61 ENST00000577001.1
ENST00000572621.5
ENST00000304992.11
pre-mRNA processing factor 8
chr7_-_47979504 3.56 ENST00000432627.5
ENST00000432325.5
ENST00000446009.1
HUS1 checkpoint clamp component
chr1_+_150067668 3.52 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
vacuolar protein sorting 45 homolog
chr11_+_67056875 3.48 ENST00000532559.1
ras homolog family member D
chr18_+_58362467 3.43 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr19_-_45423891 3.40 ENST00000300853.8
ERCC excision repair 1, endonuclease non-catalytic subunit
chr7_+_134527560 3.37 ENST00000359579.5
aldo-keto reductase family 1 member B10
chr16_-_30893990 3.31 ENST00000215115.5
BAF chromatin remodeling complex subunit BCL7C
chr2_-_112836702 3.28 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr19_-_6393131 3.27 ENST00000394456.10
general transcription factor IIF subunit 1
chr19_-_6591103 3.25 ENST00000423145.7
ENST00000245903.4
CD70 molecule
chr12_+_21501780 3.21 ENST00000229314.10
ENST00000542038.5
ENST00000540141.5
ENST00000631252.2
golgi transport 1B
chr3_+_5122276 3.09 ENST00000256496.8
ENST00000419534.2
ADP ribosylation factor like GTPase 8B
chr22_+_25219633 3.02 ENST00000398215.3
crystallin beta B2
chr11_+_43680686 2.93 ENST00000531185.5
ENST00000278353.10
hydroxysteroid 17-beta dehydrogenase 12
chr11_-_47553117 2.83 ENST00000310513.10
ENST00000531165.5
CUGBP Elav-like family member 1
chr18_+_49562049 2.75 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
lipase G, endothelial type
chr19_-_45423839 2.72 ENST00000340192.11
ERCC excision repair 1, endonuclease non-catalytic subunit
chr4_-_118836067 2.63 ENST00000280551.11
SEC24 homolog D, COPII coat complex component
chr1_+_65147514 2.61 ENST00000545314.5
adenylate kinase 4
chr4_+_26320782 2.61 ENST00000514807.5
ENST00000348160.9
recombination signal binding protein for immunoglobulin kappa J region
chr14_+_101964561 2.60 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
dynein cytoplasmic 1 heavy chain 1
chr12_+_110124329 2.59 ENST00000361948.8
ENST00000552912.5
ENST00000242591.10
ENST00000546374.5
intraflagellar transport 81
chr3_+_112086335 2.48 ENST00000431717.6
ENST00000480282.5
chromosome 3 open reading frame 52
chr3_-_123991352 2.47 ENST00000184183.8
rhophilin associated tail protein 1
chr16_-_28211908 2.46 ENST00000566073.1
ENST00000304658.10
exportin 6
chr7_-_56034133 2.44 ENST00000421626.5
phosphoserine phosphatase
chr17_-_38748184 2.43 ENST00000618941.4
ENST00000620225.5
ENST00000618506.1
ENST00000616129.4
polycomb group ring finger 2
chr11_+_67056805 2.36 ENST00000308831.7
ras homolog family member D
chr4_+_26320563 2.29 ENST00000361572.10
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_27663441 2.28 ENST00000326019.10
ENST00000613058.4
solute carrier family 4 member 1 adaptor protein
chr16_-_30894264 2.23 ENST00000380317.8
BAF chromatin remodeling complex subunit BCL7C
chr1_+_150067279 2.22 ENST00000643970.1
ENST00000535106.5
ENST00000369128.9
vacuolar protein sorting 45 homolog
chr7_+_142749465 2.19 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
serine protease 1
chr12_+_57591158 2.10 ENST00000422156.7
ENST00000354947.10
ENST00000540759.6
ENST00000551772.5
ENST00000550465.5
phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
chr4_+_26320975 2.08 ENST00000509158.6
ENST00000681856.1
ENST00000680140.1
ENST00000355476.8
ENST00000680511.1
recombination signal binding protein for immunoglobulin kappa J region
chr3_-_52056552 2.00 ENST00000495880.2
dual specificity phosphatase 7
chr12_+_100473708 1.96 ENST00000548884.5
ENST00000392986.8
nuclear receptor subfamily 1 group H member 4
chr11_+_122838492 1.87 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr1_+_12125892 1.84 ENST00000413146.6
TNF receptor superfamily member 8
chrX_+_54807599 1.82 ENST00000375053.6
ENST00000627068.2
ENST00000375068.6
ENST00000347546.8
MAGE family member D2
chr11_+_18322253 1.81 ENST00000453096.6
general transcription factor IIH subunit 1
chr3_+_112086364 1.76 ENST00000264848.10
chromosome 3 open reading frame 52
chr2_+_64989343 1.75 ENST00000234256.4
solute carrier family 1 member 4
chr4_-_185775271 1.66 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr12_+_100473916 1.60 ENST00000549996.5
nuclear receptor subfamily 1 group H member 4
chr3_-_127736329 1.58 ENST00000398101.7
monoglyceride lipase
chr5_+_149141573 1.52 ENST00000506113.5
actin binding LIM protein family member 3
chr1_+_149475045 1.52 ENST00000651566.2
NBPF member 19
chr12_+_100473951 1.49 ENST00000648861.1
ENST00000546380.1
nuclear receptor subfamily 1 group H member 4
chr12_-_93441886 1.48 ENST00000552442.1
ENST00000550657.1
ENST00000318066.7
ubiquitin conjugating enzyme E2 N
chr11_-_65595791 1.46 ENST00000340313.5
ENST00000342202.8
potassium two pore domain channel subfamily K member 7
chr3_+_140941792 1.44 ENST00000446041.6
ENST00000324194.12
ENST00000507429.5
solute carrier family 25 member 36
chr7_+_18496162 1.30 ENST00000406072.5
histone deacetylase 9
chrX_+_2828808 1.28 ENST00000381163.7
glycogenin 2
chr9_-_21187671 1.22 ENST00000421715.2
interferon alpha 4
chr5_+_160229499 1.22 ENST00000402432.4
fatty acid binding protein 6
chrX_+_109535775 1.15 ENST00000218004.5
nuclear transport factor 2 like export factor 2
chr8_-_8893548 1.14 ENST00000276282.7
malignant fibrous histiocytoma amplified sequence 1
chr20_-_23986795 1.14 ENST00000286890.8
ENST00000278765.8
gamma-glutamyltransferase light chain 1
chr17_-_43778937 1.12 ENST00000226004.8
dual specificity phosphatase 3
chr3_-_197298558 1.11 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr11_+_22668101 1.06 ENST00000630668.2
ENST00000278187.7
growth arrest specific 2
chr16_-_20741792 1.02 ENST00000396083.7
THUMP domain containing 1
chr6_-_41941795 1.02 ENST00000372991.9
cyclin D3
chr2_-_40512361 1.00 ENST00000403092.5
solute carrier family 8 member A1
chr12_-_91004965 0.97 ENST00000261172.8
epiphycan
chr8_+_109086585 0.96 ENST00000518632.2
thyrotropin releasing hormone receptor
chr12_-_4538440 0.93 ENST00000261250.8
ENST00000541014.5
ENST00000545746.5
ENST00000542080.5
chromosome 12 open reading frame 4
chr6_+_29100609 0.90 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr2_-_55296361 0.83 ENST00000647547.1
coiled-coil domain containing 88A
chr9_+_130200375 0.72 ENST00000630865.1
neuronal calcium sensor 1
chr6_-_41941728 0.71 ENST00000414200.6
cyclin D3
chr5_+_149141817 0.67 ENST00000504238.5
actin binding LIM protein family member 3
chr22_-_18518161 0.59 ENST00000619998.1
gamma-glutamyltransferase light chain family member 3
chr13_-_44161257 0.58 ENST00000400419.2
small integral membrane protein 2
chr4_+_119135825 0.57 ENST00000307128.6
myozenin 2
chr5_+_126423122 0.54 ENST00000515200.5
GRAM domain containing 2B
chr22_+_41092869 0.52 ENST00000674155.1
E1A binding protein p300
chr17_+_47209035 0.52 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr6_-_30672984 0.47 ENST00000415603.1
ENST00000376442.8
DEAH-box helicase 16
chr22_-_30560759 0.40 ENST00000437282.5
ENST00000447224.5
ENST00000427899.5
ENST00000406955.5
ENST00000452827.5
galactose-3-O-sulfotransferase 1
chr3_+_184314495 0.35 ENST00000352767.7
ENST00000414031.5
eukaryotic translation initiation factor 4 gamma 1
chr10_+_102420823 0.34 ENST00000369956.8
ENST00000425536.1
F-box and leucine rich repeat protein 15
chr22_+_22646310 0.34 ENST00000417145.2
gamma-glutamyltransferase light chain 2
chr20_-_41300066 0.28 ENST00000436099.6
ENST00000309060.7
ENST00000373261.5
ENST00000436440.6
ENST00000560364.5
ENST00000560361.5
zinc fingers and homeoboxes 3
chr18_+_21363593 0.27 ENST00000580732.6
GREB1 like retinoic acid receptor coactivator
chr5_+_140691427 0.24 ENST00000643996.1
ENST00000509299.6
ENST00000645065.1
ENST00000642752.1
ENST00000503873.6
ENST00000642970.1
ENST00000230771.9
ENST00000646468.1
ENST00000645749.1
histidyl-tRNA synthetase 2, mitochondrial
chr5_+_150660841 0.23 ENST00000297130.4
myozenin 3
chrX_+_2828921 0.21 ENST00000398806.8
glycogenin 2
chr20_+_58888779 0.21 ENST00000488546.6
ENST00000667293.2
ENST00000481039.6
ENST00000467321.6
GNAS complex locus
chr2_-_40512423 0.20 ENST00000402441.5
ENST00000448531.1
solute carrier family 8 member A1
chr19_+_38899680 0.15 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr10_+_126905409 0.09 ENST00000280333.9
ENST00000623213.2
dedicator of cytokinesis 1
chr9_+_75890639 0.06 ENST00000545128.5
proprotein convertase subtilisin/kexin type 5
chr17_+_70075215 0.05 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr17_-_29078857 0.02 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr12_-_21501551 0.00 ENST00000421138.6
ENST00000539672.1
ENST00000542432.5
ENST00000444129.7
ENST00000536964.5
ENST00000536240.5
ENST00000396093.7
ENST00000314748.10
RecQ like helicase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 28.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
5.1 20.4 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
3.6 21.8 GO:0009438 methylglyoxal metabolic process(GO:0009438)
3.3 19.9 GO:0007296 vitellogenesis(GO:0007296)
3.1 12.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
3.1 15.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
2.5 31.9 GO:0019388 galactose catabolic process(GO:0019388)
2.4 7.2 GO:0014016 neuroblast differentiation(GO:0014016)
2.4 14.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
2.4 19.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.2 6.6 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
2.2 6.6 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
2.1 6.4 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.9 7.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6 6.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
1.5 10.8 GO:1904431 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
1.4 20.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.4 11.4 GO:0048478 replication fork protection(GO:0048478)
1.4 5.5 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.3 5.0 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
1.3 6.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.2 24.2 GO:0006228 UTP biosynthetic process(GO:0006228)
1.2 3.6 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
1.2 6.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.1 9.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.1 10.1 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
1.1 3.4 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
1.1 3.3 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.0 7.0 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
1.0 8.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.9 9.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.9 3.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.9 11.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.9 3.6 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.7 2.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.7 22.8 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.7 9.8 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.6 58.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.6 1.8 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.5 2.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.5 6.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5 5.9 GO:0042407 cristae formation(GO:0042407)
0.5 11.2 GO:0006903 vesicle targeting(GO:0006903)
0.4 8.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.4 5.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 4.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 1.7 GO:0015808 L-alanine transport(GO:0015808)
0.3 8.6 GO:0031167 rRNA methylation(GO:0031167)
0.3 8.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.3 17.3 GO:0043277 apoptotic cell clearance(GO:0043277)
0.3 3.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 3.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 2.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 7.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 1.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 2.1 GO:0006751 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 5.8 GO:0002021 response to dietary excess(GO:0002021)
0.2 6.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 2.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 8.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.2 4.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.2 5.5 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2 2.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 7.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.2 1.5 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 1.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 4.8 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 3.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 20.5 GO:0032392 DNA geometric change(GO:0032392)
0.2 11.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 4.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 5.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 10.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:0018076 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 2.8 GO:0016246 RNA interference(GO:0016246)
0.1 1.9 GO:0009595 detection of biotic stimulus(GO:0009595)
0.1 6.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 1.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 8.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.0 GO:0000154 rRNA modification(GO:0000154)
0.1 4.3 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 1.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 2.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 8.3 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.0 4.4 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 2.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 2.5 GO:0032418 lysosome localization(GO:0032418)
0.0 4.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 4.6 GO:0009408 response to heat(GO:0009408)
0.0 2.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 3.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 4.5 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 15.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.2 8.9 GO:1990730 VCP-NSFL1C complex(GO:1990730)
1.8 15.8 GO:0031298 replication fork protection complex(GO:0031298)
1.6 46.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.4 10.8 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
1.2 4.7 GO:0071920 cleavage body(GO:0071920)
1.2 17.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.1 3.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
1.1 10.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
1.0 9.1 GO:0042382 paraspeckles(GO:0042382)
1.0 5.9 GO:0061617 MICOS complex(GO:0061617)
0.9 28.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.8 10.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.8 7.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7 3.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 5.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 4.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6 20.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.6 6.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6 11.9 GO:0030056 hemidesmosome(GO:0030056)
0.5 1.5 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.5 9.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 14.3 GO:0031143 pseudopodium(GO:0031143)
0.4 7.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 10.1 GO:0035371 microtubule plus-end(GO:0035371)
0.3 11.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 6.0 GO:0031932 TORC2 complex(GO:0031932)
0.3 6.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.3 5.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 2.4 GO:0001739 sex chromatin(GO:0001739)
0.2 2.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 11.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 4.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 12.0 GO:0072562 blood microparticle(GO:0072562)
0.2 14.7 GO:0060170 ciliary membrane(GO:0060170)
0.2 19.3 GO:0005882 intermediate filament(GO:0005882)
0.2 19.9 GO:0042734 presynaptic membrane(GO:0042734)
0.2 5.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 2.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 3.6 GO:0005682 U5 snRNP(GO:0005682)
0.1 5.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 5.9 GO:0043034 costamere(GO:0043034)
0.1 5.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 3.1 GO:0051233 spindle midzone(GO:0051233)
0.1 8.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 5.6 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 34.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 6.6 GO:0035580 specific granule lumen(GO:0035580)
0.1 3.7 GO:1990391 DNA repair complex(GO:1990391)
0.1 7.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 5.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 5.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 7.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 9.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 11.3 GO:0010008 endosome membrane(GO:0010008)
0.0 1.2 GO:0005771 multivesicular body(GO:0005771)
0.0 13.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.1 GO:0005769 early endosome(GO:0005769)
0.0 48.4 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.8 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 31.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
6.8 20.4 GO:0004056 argininosuccinate lyase activity(GO:0004056)
5.7 22.8 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
4.8 28.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
2.9 8.6 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
2.7 13.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
2.2 6.6 GO:0031403 lithium ion binding(GO:0031403)
2.1 6.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
2.0 21.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.9 7.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.8 7.2 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
1.8 10.6 GO:0005047 signal recognition particle binding(GO:0005047)
1.7 8.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.6 24.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.4 10.8 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.3 5.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
1.1 3.4 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
1.0 6.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.0 7.0 GO:0000150 recombinase activity(GO:0000150)
1.0 11.9 GO:0038132 neuregulin binding(GO:0038132)
1.0 28.4 GO:0000400 four-way junction DNA binding(GO:0000400)
1.0 15.7 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.9 8.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.9 3.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.9 17.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.7 2.9 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.7 19.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.7 2.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.7 4.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.6 2.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.6 6.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.6 5.7 GO:0001727 lipid kinase activity(GO:0001727)
0.6 8.8 GO:0043295 glutathione binding(GO:0043295)
0.5 9.8 GO:0097016 L27 domain binding(GO:0097016)
0.5 1.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.5 4.3 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.5 12.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.5 4.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5 3.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 10.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 15.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 2.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 6.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 1.7 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.3 6.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 4.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 3.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 8.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 3.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 6.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 7.9 GO:0015248 sterol transporter activity(GO:0015248)
0.2 20.1 GO:0097110 scaffold protein binding(GO:0097110)
0.2 14.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 3.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 6.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 5.6 GO:0005123 death receptor binding(GO:0005123)
0.2 2.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 2.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.2 GO:0032052 bile acid binding(GO:0032052)
0.1 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 5.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 8.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 17.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 9.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 3.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 3.1 GO:0019003 GDP binding(GO:0019003)
0.0 4.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 16.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 5.3 GO:0005525 GTP binding(GO:0005525)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 20.5 GO:0042802 identical protein binding(GO:0042802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 24.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.7 14.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 11.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 27.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 16.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 6.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 11.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 20.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 5.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 14.9 PID ATR PATHWAY ATR signaling pathway
0.3 12.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 10.1 PID AURORA A PATHWAY Aurora A signaling
0.2 19.6 PID E2F PATHWAY E2F transcription factor network
0.2 10.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 9.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 6.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 5.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 6.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 9.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 13.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.5 PID ATM PATHWAY ATM pathway
0.1 15.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 15.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.7 24.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 21.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 15.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.4 7.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 7.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 27.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.4 5.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 14.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.3 8.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 3.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3 9.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 6.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 5.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 4.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 1.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.4 REACTOME DEFENSINS Genes involved in Defensins
0.2 8.0 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.2 6.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 19.0 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.2 1.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 12.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 6.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 7.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.9 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 2.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 24.5 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 6.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 18.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 11.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.2 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 11.1 REACTOME TRANSLATION Genes involved in Translation
0.0 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 4.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 5.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation