avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HESX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000163666.10	HESX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HESX1	hg38_v1_chr3_-_57227596_57227621	-0.27	7.0e-05	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr14_-_105940235 Show fit	51.96	ENST00000390593.2	IGHV6-1 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 6-1
chr2_-_89117844 Show fit	27.99	ENST00000490686.1	IGKV1-17 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-17
chr2_+_90159840 Show fit	23.75	ENST00000377032.5	IGKV1D-12 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr2_-_89213917 Show fit	23.66	ENST00000498435.1	IGKV1-27 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr2_-_89100352 Show fit	23.18	ENST00000479981.1	IGKV1-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr2_+_89862438 Show fit	22.11	ENST00000448155.2	IGKV1D-39 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-39
chr2_+_90209873 Show fit	21.31	ENST00000468879.1	IGKV1D-43 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-43
chr14_-_106012390 Show fit	21.13	ENST00000455737.2	IGHV4-4 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-4
chr2_+_89913982 Show fit	19.81	ENST00000390265.2	IGKV1D-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-33
chr2_-_89297785 Show fit	18.94	ENST00000465170.1	IGKV1-37 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-37 (non-functional)
chr2_+_89884740 Show fit	18.82	ENST00000509129.1	IGKV1D-37 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-37 (non-functional)
chr2_-_89268506 Show fit	18.76	ENST00000473726.1	IGKV1-33 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-33
chr2_-_88992903 Show fit	16.13	ENST00000495489.1	IGKV1-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chr2_-_88947820 Show fit	14.30	ENST00000496168.1	IGKV1-5 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr2_-_89010515 Show fit	13.25	ENST00000493819.1	IGKV1-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr8_+_96261891 Show fit	12.83	ENST00000517309.6	PTDSS1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylserine synthase 1
chr2_+_90154073 Show fit	12.79	ENST00000611391.1	IGKV1D-13 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-13
chr2_-_61538180 Show fit	12.70	ENST00000677150.1 ENST00000678182.1 ENST00000677928.1 ENST00000406957.5	XPO1 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 1
chr2_-_61538290 Show fit	12.52	ENST00000678790.1	XPO1 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 1
chr2_-_61538313 Show fit	12.46	ENST00000677803.1 ENST00000677239.1 ENST00000401558.7	XPO1 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 1
chr2_+_113406368 Show fit	12.34	ENST00000453673.3	IGKV1OR2-108 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr2_-_61538516 Show fit	11.33	ENST00000676771.1 ENST00000677814.1 ENST00000443240.5 ENST00000677556.1 ENST00000676553.1	XPO1 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 1
chr12_-_46268989 Show fit	10.77	ENST00000549049.5 ENST00000439706.5 ENST00000398637.10	SLC38A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 1
chr1_+_47333774 Show fit	10.28	ENST00000371873.10	CMPK1 Links Ensembl NCBI GeneCards UniProt Show fit	cytidine/uridine monophosphate kinase 1
chr11_-_126268810 Show fit	10.09	ENST00000332118.11	SRPRA Links Ensembl NCBI GeneCards UniProt Show fit	SRP receptor subunit alpha
chr2_-_88966767 Show fit	9.66	ENST00000464162.1	IGKV1-6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-6
chr1_+_45550783 Show fit	9.57	ENST00000621846.4 ENST00000434299.5 ENST00000351829.9	AKR1A1 Links Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member A1
chr15_+_80072559 Show fit	8.99	ENST00000560228.5 ENST00000559835.5 ENST00000559775.5 ENST00000558688.5 ENST00000560392.5 ENST00000560976.5 ENST00000558272.5 ENST00000558390.5	ZFAND6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr11_+_102347205 Show fit	8.56	ENST00000532832.5 ENST00000530675.5 ENST00000227758.7 ENST00000533742.5 ENST00000532672.5 ENST00000531259.5 ENST00000527465.1	BIRC2 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 2
chr3_+_158801926 Show fit	8.54	ENST00000622669.4 ENST00000392813.8 ENST00000415822.8 ENST00000651862.1 ENST00000264266.12	MFSD1 Links Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 1
chr15_+_66453418 Show fit	7.89	ENST00000566326.1	MAP2K1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 1
chr1_-_53945661 Show fit	7.64	ENST00000194214.10	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr12_-_120581361 Show fit	7.57	ENST00000341039.6 ENST00000357500.5	POP5 Links Ensembl NCBI GeneCards UniProt Show fit	POP5 homolog, ribonuclease P/MRP subunit
chr20_+_37179310 Show fit	7.17	ENST00000373632.8 ENST00000237530.11	RPN2 Links Ensembl NCBI GeneCards UniProt Show fit	ribophorin II
chr5_-_88883701 Show fit	6.94	ENST00000636998.1	MEF2C Links Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr11_+_102347312 Show fit	6.92	ENST00000621637.1 ENST00000613397.4	BIRC2 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 2
chr20_+_37179109 Show fit	6.55	ENST00000373622.9	RPN2 Links Ensembl NCBI GeneCards UniProt Show fit	ribophorin II
chr1_-_109426410 Show fit	6.50	ENST00000271308.9	PSMA5 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 5
chr5_+_163437569 Show fit	6.46	ENST00000512163.5 ENST00000393929.5 ENST00000510097.5 ENST00000340828.7 ENST00000511490.4 ENST00000510664.5	CCNG1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G1
chr12_-_53676720 Show fit	6.34	ENST00000673498.1	ATP5MC2 Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 2
chr12_+_103930600 Show fit	5.61	ENST00000680316.1 ENST00000679861.1	HSP90B1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein 90 beta family member 1
chr11_+_65181920 Show fit	5.43	ENST00000279247.11 ENST00000532285.1 ENST00000534373.5	CAPN1 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr20_+_49219398 Show fit	5.35	ENST00000618172.5	DDX27 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 27
chr11_-_118342691 Show fit	5.10	ENST00000300692.9	CD3D Links Ensembl NCBI GeneCards UniProt Show fit	CD3d molecule
chr2_+_90220727 Show fit	5.03	ENST00000471857.2	IGKV1D-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-8
chr11_-_66438788 Show fit	5.03	ENST00000329819.4 ENST00000310999.11 ENST00000430466.6	MRPL11 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L11
chr12_-_53676314 Show fit	5.01	ENST00000549164.5	ATP5MC2 Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 2
chr5_+_40679907 Show fit	4.91	ENST00000302472.4	PTGER4 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 4
chr21_-_33479914 Show fit	4.78	ENST00000542230.7	TMEM50B Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 50B
chr20_-_63956382 Show fit	4.72	ENST00000358711.7 ENST00000354216.11	UCKL1 Links Ensembl NCBI GeneCards UniProt Show fit	uridine-cytidine kinase 1 like 1
chr14_-_24634160 Show fit	4.54	ENST00000616551.1 ENST00000382542.5 ENST00000216341.9 ENST00000526004.1 ENST00000415355.7	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr14_-_24195334 Show fit	4.48	ENST00000530563.1 ENST00000528895.5 ENST00000528669.5 ENST00000532632.1 ENST00000261789.9	TM9SF1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 1
chr10_-_43408787 Show fit	4.39	ENST00000356053.7	HNRNPF Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr6_-_41736239 Show fit	4.39	ENST00000358871.6	TFEB Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor EB
chr10_-_45594760 Show fit	4.31	ENST00000319836.7	MARCHF8 Links Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 8
chr14_-_24634266 Show fit	4.30	ENST00000382540.5	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr17_-_41918944 Show fit	4.22	ENST00000352035.7 ENST00000590770.5 ENST00000590151.5	ACLY Links Ensembl NCBI GeneCards UniProt Show fit	ATP citrate lyase
chr2_+_121737100 Show fit	4.17	ENST00000455432.5	TSN Links Ensembl NCBI GeneCards UniProt Show fit	translin
chr14_+_20469399 Show fit	4.17	ENST00000361505.10 ENST00000553591.1	PNP Links Ensembl NCBI GeneCards UniProt Show fit	purine nucleoside phosphorylase
chr7_+_70596078 Show fit	4.05	ENST00000644506.1	AUTS2 Links Ensembl NCBI GeneCards UniProt Show fit	activator of transcription and developmental regulator AUTS2
chr3_+_133574434 Show fit	3.85	ENST00000508481.5 ENST00000420115.6 ENST00000504867.5 ENST00000507408.5 ENST00000511392.5 ENST00000515421.1	CDV3 Links Ensembl NCBI GeneCards UniProt Show fit	CDV3 homolog
chr20_+_1135178 Show fit	3.74	ENST00000435720.5	PSMF1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome inhibitor subunit 1
chr18_+_12947982 Show fit	3.63	ENST00000262124.15	SEH1L Links Ensembl NCBI GeneCards UniProt Show fit	SEH1 like nucleoporin
chr10_-_70233420 Show fit	3.56	ENST00000373232.8 ENST00000625364.1	PPA1 Links Ensembl NCBI GeneCards UniProt Show fit	inorganic pyrophosphatase 1
chr17_+_47209375 Show fit	3.54	ENST00000572303.1	MYL4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr14_-_100376251 Show fit	3.52	ENST00000556645.5 ENST00000556209.5 ENST00000556504.5 ENST00000556435.5 ENST00000554772.5 ENST00000553581.1 ENST00000553769.6 ENST00000554605.5 ENST00000557722.5 ENST00000553413.5 ENST00000553524.5 ENST00000358655.8	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr14_-_100375602 Show fit	3.33	ENST00000553395.5 ENST00000553545.5 ENST00000344102.9 ENST00000556338.5 ENST00000553934.1	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr7_+_12687625 Show fit	3.30	ENST00000651779.1 ENST00000404894.1	ARL4A Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 4A
chr19_-_49867251 Show fit	3.28	ENST00000631020.2 ENST00000596014.5 ENST00000636994.1	PNKP Links Ensembl NCBI GeneCards UniProt Show fit	polynucleotide kinase 3'-phosphatase
chr11_+_18394586 Show fit	3.14	ENST00000227157.8 ENST00000478970.6 ENST00000495052.5	LDHA Links Ensembl NCBI GeneCards UniProt Show fit	lactate dehydrogenase A
chr22_+_19432512 Show fit	3.04	ENST00000333130.4	MRPL40 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L40
chr18_+_12948001 Show fit	3.03	ENST00000399892.7 ENST00000585730.5 ENST00000589446.5 ENST00000587761.1	SEH1L Links Ensembl NCBI GeneCards UniProt Show fit	SEH1 like nucleoporin
chr17_+_47209035 Show fit	3.00	ENST00000572316.5 ENST00000354968.5 ENST00000576874.5 ENST00000536623.6	MYL4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr18_-_12883766 Show fit	2.97	ENST00000645191.1 ENST00000646492.1	PTPN2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 2
chr11_+_118572373 Show fit	2.87	ENST00000392859.7 ENST00000264028.5 ENST00000614498.4 ENST00000359415.8 ENST00000534182.2	ARCN1 Links Ensembl NCBI GeneCards UniProt Show fit	archain 1
chr16_-_66934144 Show fit	2.72	ENST00000568572.5	CIAO2B Links Ensembl NCBI GeneCards UniProt Show fit	cytosolic iron-sulfur assembly component 2B
chr9_+_129835442 Show fit	2.67	ENST00000372429.8 ENST00000315480.9 ENST00000358355.5	USP20 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 20
chr22_+_23894375 Show fit	2.66	ENST00000215754.8	MIF Links Ensembl NCBI GeneCards UniProt Show fit	macrophage migration inhibitory factor
chr17_-_41918966 Show fit	2.65	ENST00000537919.5 ENST00000353196.5 ENST00000393896.6	ACLY Links Ensembl NCBI GeneCards UniProt Show fit	ATP citrate lyase
chr17_-_82317523 Show fit	2.62	ENST00000583376.1 ENST00000578509.1 ENST00000584284.5 ENST00000582480.1	CD7 Links Ensembl NCBI GeneCards UniProt Show fit	CD7 molecule
chr1_+_151399557 Show fit	2.58	ENST00000290541.7	PSMB4 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 4
chr11_-_126268913 Show fit	2.56	ENST00000532259.1	SRPRA Links Ensembl NCBI GeneCards UniProt Show fit	SRP receptor subunit alpha
chr2_-_37672448 Show fit	2.53	ENST00000611976.1	CDC42EP3 Links Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein 3
chr4_-_48780242 Show fit	2.38	ENST00000507711.5 ENST00000358350.9	FRYL Links Ensembl NCBI GeneCards UniProt Show fit	FRY like transcription coactivator
chr22_+_43955424 Show fit	2.21	ENST00000350028.5	SAMM50 Links Ensembl NCBI GeneCards UniProt Show fit	SAMM50 sorting and assembly machinery component
chr4_-_16083695 Show fit	2.17	ENST00000510224.5	PROM1 Links Ensembl NCBI GeneCards UniProt Show fit	prominin 1
chr4_-_16083714 Show fit	2.04	ENST00000508167.5	PROM1 Links Ensembl NCBI GeneCards UniProt Show fit	prominin 1
chr19_+_37907200 Show fit	2.04	ENST00000222345.11	SIPA1L3 Links Ensembl NCBI GeneCards UniProt Show fit	signal induced proliferation associated 1 like 3
chr8_+_6708626 Show fit	2.03	ENST00000285518.11	AGPAT5 Links Ensembl NCBI GeneCards UniProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 5
chr2_-_43595963 Show fit	1.97	ENST00000405006.8	THADA Links Ensembl NCBI GeneCards UniProt Show fit	THADA armadillo repeat containing
chr1_-_53945584 Show fit	1.88	ENST00000371377.3	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr10_+_74176741 Show fit	1.86	ENST00000673027.1 ENST00000372734.5 ENST00000541550.6	ADK Links Ensembl NCBI GeneCards UniProt Show fit	adenosine kinase
chr15_+_45023137 Show fit	1.69	ENST00000674211.1 ENST00000267814.14	SORD Links Ensembl NCBI GeneCards UniProt Show fit	sorbitol dehydrogenase
chr2_-_43595980 Show fit	1.69	ENST00000403856.1 ENST00000404790.5 ENST00000405975.7	THADA Links Ensembl NCBI GeneCards UniProt Show fit	THADA armadillo repeat containing
chr4_+_153684241 Show fit	1.61	ENST00000646219.1 ENST00000642580.1 ENST00000643501.1 ENST00000642700.2	TLR2 Links Ensembl NCBI GeneCards UniProt Show fit	toll like receptor 2
chr1_-_205321737 Show fit	1.61	ENST00000367157.6	NUAK2 Links Ensembl NCBI GeneCards UniProt Show fit	NUAK family kinase 2
chr9_+_69174217 Show fit	1.60	ENST00000348208.9 ENST00000377245.9 ENST00000649943.1 ENST00000649114.1 ENST00000650333.1	TJP2 Links Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 2
chr6_+_85450033 Show fit	1.45	ENST00000257770.8 ENST00000369646.7	NT5E Links Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr8_+_78516329 Show fit	1.44	ENST00000396418.7 ENST00000352966.9	PKIA Links Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor alpha
chr2_+_134254065 Show fit	1.44	ENST00000281923.4	MGAT5 Links Ensembl NCBI GeneCards UniProt Show fit	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr6_+_31971831 Show fit	1.42	ENST00000375331.7 ENST00000375333.3	STK19 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 19
chr7_+_127588355 Show fit	1.39	ENST00000415666.1 ENST00000000233.10	ARF5 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 5
chr19_-_49867542 Show fit	1.33	ENST00000600910.5 ENST00000322344.8 ENST00000600573.5 ENST00000596726.3 ENST00000638016.1	PNKP Links Ensembl NCBI GeneCards UniProt Show fit	polynucleotide kinase 3'-phosphatase
chr2_-_96265942 Show fit	1.32	ENST00000432959.1 ENST00000258439.8	TMEM127 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 127
chr3_+_15206179 Show fit	1.30	ENST00000253693.7	CAPN7 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 7
chr12_+_27332849 Show fit	1.27	ENST00000544915.5 ENST00000395901.6 ENST00000546179.5	ARNTL2 Links Ensembl NCBI GeneCards UniProt Show fit	aryl hydrocarbon receptor nuclear translocator like 2
chrX_-_65534721 Show fit	1.23	ENST00000677969.1 ENST00000374807.9 ENST00000374804.9 ENST00000677087.1 ENST00000374811.8 ENST00000676986.1 ENST00000678823.1 ENST00000678570.1	LAS1L Links Ensembl NCBI GeneCards UniProt Show fit	LAS1 like ribosome biogenesis factor
chr1_-_1232061 Show fit	1.09	ENST00000660930.1	SDF4 Links Ensembl NCBI GeneCards UniProt Show fit	stromal cell derived factor 4
chr17_+_47209338 Show fit	1.08	ENST00000393450.5	MYL4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr6_+_85449584 Show fit	1.07	ENST00000369651.7	NT5E Links Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr8_-_96261579 Show fit	1.06	ENST00000517720.1 ENST00000523821.5 ENST00000287025.4	MTERF3 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial transcription termination factor 3
chr9_-_5833014 Show fit	1.04	ENST00000339450.10	ERMP1 Links Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum metallopeptidase 1
chr1_-_43172504 Show fit	1.00	ENST00000431635.6	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr16_+_84699969 Show fit	0.97	ENST00000563892.5 ENST00000219473.12 ENST00000562283.5 ENST00000570191.5 ENST00000569038.5 ENST00000570053.1	USP10 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 10
chr8_+_123072667 Show fit	0.93	ENST00000519418.5 ENST00000287380.6 ENST00000327098.9 ENST00000522420.5 ENST00000521676.5	TBC1D31 Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 31
chr6_-_144008118 Show fit	0.82	ENST00000629195.2 ENST00000650125.1 ENST00000647880.1 ENST00000649307.1 ENST00000674357.1 ENST00000417959.4 ENST00000635591.1	PLAGL1 Links Ensembl NCBI GeneCards UniProt Show fit HYMAI Links Ensembl NCBI GeneCards UniProt Show fit	PLAG1 like zinc finger 1 hydatidiform mole associated and imprinted
chr7_+_101815904 Show fit	0.78	ENST00000437600.9 ENST00000645010.1 ENST00000646649.1	CUX1 Links Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 1
chr1_-_1231966 Show fit	0.76	ENST00000360001.12	SDF4 Links Ensembl NCBI GeneCards UniProt Show fit	stromal cell derived factor 4
chr11_-_57381146 Show fit	0.76	ENST00000287143.2	PRG3 Links Ensembl NCBI GeneCards UniProt Show fit	proteoglycan 3, pro eosinophil major basic protein 2
chr19_+_32581178 Show fit	0.75	ENST00000590247.7 ENST00000419343.7 ENST00000592786.5 ENST00000379316.3	PDCD5 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 5
chr2_+_129979641 Show fit	0.64	ENST00000410061.4	RAB6C Links Ensembl NCBI GeneCards UniProt Show fit	RAB6C, member RAS oncogene family
chrX_+_136648138 Show fit	0.61	ENST00000370629.7	CD40LG Links Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr11_-_72080472 Show fit	0.60	ENST00000537217.5 ENST00000366394.7 ENST00000358965.10 ENST00000546131.1 ENST00000393695.8 ENST00000543937.5 ENST00000368959.9 ENST00000541641.5	NUMA1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear mitotic apparatus protein 1
chr12_-_56630293 Show fit	0.58	ENST00000546695.5 ENST00000549884.6	BAZ2A Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 2A
chr16_-_14630200 Show fit	0.57	ENST00000650990.1 ENST00000651049.1 ENST00000652727.1 ENST00000652501.1 ENST00000539279.5 ENST00000651634.1 ENST00000651027.1 ENST00000420015.6 ENST00000651865.1 ENST00000437198.7 ENST00000341484.11 ENST00000650960.1	PARN Links Ensembl NCBI GeneCards UniProt Show fit	poly(A)-specific ribonuclease
chr11_-_1608463 Show fit	0.56	ENST00000399685.1	KRTAP5-3 Links Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 5-3
chr1_-_1232031 Show fit	0.50	ENST00000263741.12	SDF4 Links Ensembl NCBI GeneCards UniProt Show fit	stromal cell derived factor 4
chr22_+_44752552 Show fit	0.46	ENST00000389774.6 ENST00000356099.11 ENST00000396119.6 ENST00000336963.8 ENST00000412433.5	ARHGAP8 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 8
chr16_-_57186014 Show fit	0.41	ENST00000566584.5 ENST00000566481.5 ENST00000566077.5 ENST00000564108.5 ENST00000309137.13 ENST00000565458.5 ENST00000566681.1 ENST00000567439.5	PSME3IP1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 3 interacting protein 1
chr12_-_113471851 Show fit	0.39	ENST00000261731.4	LHX5 Links Ensembl NCBI GeneCards UniProt Show fit	LIM homeobox 5
chr12_-_643620 Show fit	0.39	ENST00000433832.2 ENST00000542920.1	NINJ2 Links Ensembl NCBI GeneCards UniProt Show fit	ninjurin 2
chr12_-_123233097 Show fit	0.37	ENST00000541437.5 ENST00000606320.6	MPHOSPH9 Links Ensembl NCBI GeneCards UniProt Show fit	M-phase phosphoprotein 9
chrX_+_136648214 Show fit	0.37	ENST00000370628.2	CD40LG Links Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr7_-_36985060 Show fit	0.33	ENST00000396040.6	ELMO1 Links Ensembl NCBI GeneCards UniProt Show fit	engulfment and cell motility 1
chr6_+_52420332 Show fit	0.31	ENST00000636107.1 ENST00000371068.11 ENST00000636702.1 ENST00000635996.1 ENST00000636379.1	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr11_-_4393650 Show fit	0.25	ENST00000254436.8	TRIM21 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 21
chr3_-_51941874 Show fit	0.24	ENST00000232888.7	RRP9 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr1_-_20119527 Show fit	0.24	ENST00000375105.8 ENST00000617227.1	PLA2G2D Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IID
chr15_+_32030506 Show fit	0.23	ENST00000306901.9 ENST00000636440.1	CHRNA7 Links Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 7 subunit
chr11_-_72080389 Show fit	0.21	ENST00000351960.10 ENST00000541719.5 ENST00000535111.5	NUMA1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear mitotic apparatus protein 1
chr8_+_145052447 Show fit	0.18	ENST00000331434.7 ENST00000648531.1 ENST00000647640.1 ENST00000647724.1 ENST00000648784.1	C8orf33 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 33
chr17_-_38853629 Show fit	0.15	ENST00000378096.3 ENST00000479035.7 ENST00000394332.5 ENST00000394333.5 ENST00000577407.5	RPL23 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L23
chr1_+_53946323 Show fit	0.14	ENST00000371370.8 ENST00000319223.8 ENST00000444987.1	LRRC42 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 42
chr14_+_45084093 Show fit	0.13	ENST00000553605.1 ENST00000355765.11	PRPF39 Links Ensembl NCBI GeneCards UniProt Show fit	pre-mRNA processing factor 39
chr2_+_240605417 Show fit	0.12	ENST00000319838.10 ENST00000403859.1	GPR35 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 35
chr18_-_60372767 Show fit	0.09	ENST00000299766.5	MC4R Links Ensembl NCBI GeneCards UniProt Show fit	melanocortin 4 receptor
chr19_+_44809089 Show fit	0.08	ENST00000270233.12 ENST00000591520.6	BCAM Links Ensembl NCBI GeneCards UniProt Show fit	basal cell adhesion molecule (Lutheran blood group)
chr10_+_119892692 Show fit	0.07	ENST00000369075.8	SEC23IP Links Ensembl NCBI GeneCards UniProt Show fit	SEC23 interacting protein
chr11_+_71538025 Show fit	0.01	ENST00000398534.4	KRTAP5-8 Links Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 5-8
chr1_-_203175783 Show fit	0.01	ENST00000621380.1 ENST00000255416.9	MYBPH Links Ensembl NCBI GeneCards UniProt Show fit	myosin binding protein H

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.2	15.5	GO:1902524	positive regulation of protein K48-linked ubiquitination(GO:1902524)
4.5	49.0	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
1.6	4.9	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
1.6	12.8	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
1.5	219.4	GO:0006958	complement activation, classical pathway(GO:0006958)
1.4	4.1	GO:0098582	innate vocalization behavior(GO:0098582)
1.3	10.3	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.2	7.5	GO:1901159	glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
1.2	3.7	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.2	4.6	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
1.1	7.9	GO:0090170	regulation of Golgi inheritance(GO:0090170)
1.0	4.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
1.0	3.0	GO:1903970	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) regulation of positive thymic T cell selection(GO:1902232) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.9	6.9	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.8	7.6	GO:0009249	protein lipoylation(GO:0009249)
0.8	1.6	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.8	4.7	GO:0044211	CTP salvage(GO:0044211)
0.8	2.4	GO:0070625	zymogen granule exocytosis(GO:0070625)
0.7	4.4	GO:0046086	adenosine biosynthetic process(GO:0046086)
0.7	2.9	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.7	2.7	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.7	117.8	GO:0002377	immunoglobulin production(GO:0002377)
0.6	9.5	GO:0070986	left/right axis specification(GO:0070986)
0.6	5.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6	6.7	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.6	4.2	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.5	5.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.4	5.6	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.4	6.7	GO:0097264	self proteolysis(GO:0097264)
0.4	6.9	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.3	3.0	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.3	9.0	GO:0072663	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.3	4.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.3	0.8	GO:0055048	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2	2.6	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2	10.8	GO:0001504	neurotransmitter uptake(GO:0001504)
0.2	13.7	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.2	3.1	GO:0006089	lactate metabolic process(GO:0006089)
0.2	1.6	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.2	7.6	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.2	0.6	GO:0090669	telomerase RNA stabilization(GO:0090669)
0.2	2.5	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	2.0	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.8	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.2	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.1	5.0	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	3.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.1	2.4	GO:0090527	actin filament reorganization(GO:0090527)
0.1	10.2	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.1	0.4	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	12.8	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	1.2	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.1	5.3	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	1.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	3.3	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	2.7	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.2	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	4.4	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	2.6	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	2.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	6.5	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1	4.4	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.1	1.1	GO:0042255	ribosome assembly(GO:0042255)
0.0	1.3	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.6	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	3.0	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	12.7	GO:0002250	adaptive immune response(GO:0002250)
0.0	0.2	GO:0050893	sensory processing(GO:0050893)
0.0	1.0	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	1.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	1.0	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:2000252	diet induced thermogenesis(GO:0002024) negative regulation of feeding behavior(GO:2000252)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	49.0	GO:0005642	annulate lamellae(GO:0005642)
1.3	69.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
1.3	12.6	GO:0005785	signal recognition particle receptor complex(GO:0005785)
1.3	7.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
1.1	13.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
1.0	15.5	GO:0001741	XY body(GO:0001741)
0.8	6.7	GO:0061700	GATOR2 complex(GO:0061700)
0.6	102.6	GO:0072562	blood microparticle(GO:0072562)
0.5	6.5	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.5	1.6	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.5	5.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.4	9.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.4	5.6	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.4	3.7	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3	6.3	GO:0005839	proteasome core complex(GO:0005839)
0.3	0.8	GO:0055028	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.3	2.0	GO:0061689	tricellular tight junction(GO:0061689)
0.2	4.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	2.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.2	2.4	GO:0032059	bleb(GO:0032059)
0.1	4.5	GO:0000421	autophagosome membrane(GO:0000421)
0.1	8.8	GO:0001772	immunological synapse(GO:0001772)
0.1	0.6	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	7.6	GO:0031672	A band(GO:0031672)
0.1	18.6	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	2.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	90.2	GO:0005615	extracellular space(GO:0005615)
0.1	2.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.8	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	3.0	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	7.7	GO:0005769	early endosome(GO:0005769)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	20.9	GO:0005730	nucleolus(GO:0005730)
0.0	0.6	GO:0045095	keratin filament(GO:0045095)
0.0	54.3	GO:0005576	extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	15.5	GO:0098770	FBXO family protein binding(GO:0098770)
3.4	10.3	GO:0009041	uridylate kinase activity(GO:0009041)
3.3	49.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
2.1	12.6	GO:0005047	signal recognition particle binding(GO:0005047)
1.4	13.7	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.3	321.2	GO:0003823	antigen binding(GO:0003823)
1.3	7.6	GO:0032038	myosin II heavy chain binding(GO:0032038)
1.2	4.6	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.0	4.2	GO:0002060	purine nucleobase binding(GO:0002060)
1.0	3.0	GO:0097677	STAT family protein binding(GO:0097677)
1.0	6.9	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8	2.5	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.8	4.7	GO:0004849	uridine kinase activity(GO:0004849)
0.7	3.6	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.6	5.8	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6	7.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.5	2.7	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.5	5.6	GO:0046790	virion binding(GO:0046790)
0.5	4.9	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.5	1.9	GO:0004001	adenosine kinase activity(GO:0004001)
0.4	3.1	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.4	6.9	GO:0003680	AT DNA binding(GO:0003680)
0.3	10.8	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.3	1.0	GO:0005174	CD40 receptor binding(GO:0005174)
0.3	9.1	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	1.6	GO:0071723	lipopeptide binding(GO:0071723)
0.3	0.8	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.2	7.9	GO:0004708	MAP kinase kinase activity(GO:0004708) protein serine/threonine kinase activator activity(GO:0043539)
0.2	6.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	3.7	GO:0070628	proteasome binding(GO:0070628)
0.1	9.0	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	1.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	4.4	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.8	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	2.0	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	6.2	GO:0019843	rRNA binding(GO:0019843)
0.1	5.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	1.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	4.2	GO:0042805	actinin binding(GO:0042805)
0.1	3.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	8.1	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	1.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	4.2	GO:0004519	endonuclease activity(GO:0004519)
0.0	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.6	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0005055	laminin receptor activity(GO:0005055)
0.0	1.3	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	45.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.6	24.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4	7.9	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	4.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	6.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	5.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	6.6	PID P53 REGULATION PATHWAY	p53 pathway
0.1	3.0	PID IFNG PATHWAY	IFN-gamma pathway
0.1	5.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	2.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	2.6	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	49.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7	7.9	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.4	6.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	5.6	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4	3.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.4	4.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	15.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.3	10.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	2.9	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	5.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	10.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	8.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.2	6.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2	12.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2	6.9	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.2	1.6	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	5.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	3.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	7.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	12.7	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.1	0.8	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	2.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	1.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	3.8	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	2.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	2.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell