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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for HIC2
Z-value: 7.76
Motif logo
Transcription factors associated with HIC2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HIC2
|
ENSG00000169635.10 | HIC2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HIC2 | hg38_v1_chr22_+_21420636_21420669 | 0.20 | 3.8e-03 | Click! |
Activity profile of HIC2 motif
Sorted Z-values of HIC2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HIC2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.3 | 33.2 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 7.7 | 30.9 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 7.0 | 21.0 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 5.1 | 20.4 | GO:0090301 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 5.0 | 14.9 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
| 4.8 | 19.0 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 4.6 | 13.9 | GO:0019075 | virus maturation(GO:0019075) |
| 4.5 | 22.4 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 4.5 | 17.9 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 3.9 | 19.6 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 3.9 | 11.8 | GO:0035759 | mesangial cell-matrix adhesion(GO:0035759) |
| 3.9 | 11.7 | GO:0006683 | galactosylceramide catabolic process(GO:0006683) |
| 3.8 | 19.0 | GO:0035106 | operant conditioning(GO:0035106) |
| 3.7 | 11.1 | GO:0009386 | translational attenuation(GO:0009386) |
| 3.7 | 21.9 | GO:0070829 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 3.7 | 11.0 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 3.6 | 10.9 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 3.6 | 10.9 | GO:0051941 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 3.6 | 14.6 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 3.6 | 7.3 | GO:0038109 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 3.6 | 10.8 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
| 3.6 | 14.3 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 3.6 | 10.7 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 3.5 | 10.4 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 3.5 | 17.3 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 3.4 | 13.6 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 3.4 | 20.4 | GO:0010732 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 3.4 | 16.9 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 3.4 | 23.5 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 3.3 | 13.3 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 3.2 | 9.7 | GO:0036292 | DNA rewinding(GO:0036292) |
| 3.2 | 9.6 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 3.2 | 22.4 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 3.2 | 12.7 | GO:0021759 | globus pallidus development(GO:0021759) |
| 3.2 | 15.8 | GO:0044858 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 3.1 | 6.3 | GO:0072277 | metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
| 3.1 | 9.3 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769) |
| 3.1 | 12.3 | GO:1900106 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 3.1 | 12.2 | GO:0010652 | regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) |
| 3.0 | 9.1 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 2.9 | 11.7 | GO:0050757 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) |
| 2.9 | 23.2 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 2.9 | 11.5 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 2.8 | 2.8 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 2.8 | 14.1 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 2.8 | 19.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 2.8 | 28.1 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 2.8 | 2.8 | GO:0071288 | cellular response to mercury ion(GO:0071288) |
| 2.7 | 5.4 | GO:0060435 | bronchiole development(GO:0060435) |
| 2.7 | 8.0 | GO:0001300 | chronological cell aging(GO:0001300) |
| 2.6 | 7.8 | GO:0035054 | embryonic heart tube anterior/posterior pattern specification(GO:0035054) |
| 2.6 | 5.1 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 2.5 | 7.5 | GO:0051939 | gamma-aminobutyric acid import(GO:0051939) |
| 2.5 | 7.5 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 2.4 | 7.3 | GO:0001812 | positive regulation of type I hypersensitivity(GO:0001812) |
| 2.4 | 12.0 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 2.4 | 7.1 | GO:0005989 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 2.4 | 11.8 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 2.4 | 14.2 | GO:0048807 | female genitalia morphogenesis(GO:0048807) |
| 2.4 | 9.5 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 2.4 | 4.7 | GO:1902913 | positive regulation of neuroepithelial cell differentiation(GO:1902913) |
| 2.3 | 13.8 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 2.3 | 9.1 | GO:0072103 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
| 2.3 | 18.1 | GO:0015705 | iodide transport(GO:0015705) |
| 2.2 | 6.7 | GO:0019046 | release from viral latency(GO:0019046) |
| 2.2 | 6.7 | GO:1904640 | response to methionine(GO:1904640) |
| 2.2 | 6.7 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
| 2.2 | 26.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 2.2 | 17.4 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 2.2 | 13.0 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 2.1 | 6.4 | GO:0008355 | olfactory learning(GO:0008355) |
| 2.1 | 6.4 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 2.1 | 4.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 2.1 | 10.6 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 2.1 | 12.6 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 2.1 | 14.6 | GO:0086017 | Purkinje myocyte action potential(GO:0086017) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) |
| 2.1 | 12.5 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 2.1 | 6.2 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 2.1 | 8.2 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 2.0 | 12.1 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 2.0 | 6.0 | GO:0048570 | notochord morphogenesis(GO:0048570) |
| 2.0 | 42.1 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 2.0 | 6.0 | GO:0051040 | regulation of calcium-independent cell-cell adhesion(GO:0051040) |
| 2.0 | 9.9 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 2.0 | 19.6 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 1.9 | 7.8 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 1.9 | 13.6 | GO:0010901 | regulation of very-low-density lipoprotein particle remodeling(GO:0010901) |
| 1.9 | 9.6 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 1.9 | 21.0 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 1.9 | 7.6 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 1.9 | 11.3 | GO:0018343 | protein farnesylation(GO:0018343) |
| 1.9 | 5.6 | GO:0001757 | somite specification(GO:0001757) |
| 1.9 | 5.6 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 1.8 | 5.5 | GO:0060086 | circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 1.8 | 7.3 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 1.8 | 9.1 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 1.8 | 7.3 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 1.8 | 5.4 | GO:0030035 | microspike assembly(GO:0030035) |
| 1.8 | 12.7 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 1.8 | 5.4 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 1.8 | 12.4 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 1.8 | 3.5 | GO:0035973 | aggrephagy(GO:0035973) |
| 1.8 | 1.8 | GO:0033091 | positive regulation of immature T cell proliferation(GO:0033091) |
| 1.8 | 5.3 | GO:0007538 | primary sex determination(GO:0007538) |
| 1.7 | 8.6 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 1.7 | 3.4 | GO:0060513 | prostatic bud formation(GO:0060513) |
| 1.7 | 5.1 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 1.7 | 5.1 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) |
| 1.7 | 8.5 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 1.7 | 15.2 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 1.7 | 10.1 | GO:0021553 | olfactory nerve development(GO:0021553) |
| 1.7 | 5.0 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 1.6 | 3.3 | GO:0018963 | phthalate metabolic process(GO:0018963) |
| 1.6 | 4.8 | GO:2000374 | lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374) |
| 1.6 | 4.8 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.6 | 4.8 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 1.6 | 6.4 | GO:0048627 | myoblast development(GO:0048627) |
| 1.6 | 12.8 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 1.6 | 4.8 | GO:0019482 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) |
| 1.6 | 11.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.6 | 6.3 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.5 | 6.2 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 1.5 | 18.6 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 1.5 | 4.6 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 1.5 | 4.6 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 1.5 | 3.1 | GO:0021650 | vestibulocochlear nerve formation(GO:0021650) |
| 1.5 | 6.1 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 1.5 | 3.1 | GO:0046533 | negative regulation of photoreceptor cell differentiation(GO:0046533) |
| 1.5 | 4.6 | GO:0001842 | neural fold formation(GO:0001842) |
| 1.5 | 6.1 | GO:0060948 | cardiac vascular smooth muscle cell development(GO:0060948) |
| 1.5 | 7.5 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 1.5 | 9.0 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 1.5 | 7.4 | GO:0035900 | response to isolation stress(GO:0035900) |
| 1.5 | 4.4 | GO:0072233 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 1.5 | 1.5 | GO:0014734 | skeletal muscle hypertrophy(GO:0014734) |
| 1.5 | 4.4 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 1.5 | 5.8 | GO:0048865 | stem cell fate commitment(GO:0048865) |
| 1.4 | 4.3 | GO:0006522 | alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) |
| 1.4 | 4.3 | GO:1902263 | apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 1.4 | 8.5 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 1.4 | 4.2 | GO:0071934 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 1.4 | 4.2 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 1.4 | 2.8 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 1.4 | 12.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 1.4 | 39.2 | GO:0001502 | cartilage condensation(GO:0001502) |
| 1.4 | 2.8 | GO:1902949 | positive regulation of tau-protein kinase activity(GO:1902949) |
| 1.4 | 2.8 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 1.4 | 4.1 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 1.4 | 2.7 | GO:0002386 | immune response in mucosal-associated lymphoid tissue(GO:0002386) |
| 1.4 | 6.8 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 1.4 | 8.1 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 1.4 | 4.1 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 1.3 | 6.7 | GO:0006116 | NADH oxidation(GO:0006116) |
| 1.3 | 8.1 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 1.3 | 5.4 | GO:0036018 | cellular response to erythropoietin(GO:0036018) |
| 1.3 | 5.3 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 1.3 | 9.3 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 1.3 | 6.6 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 1.3 | 5.3 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 1.3 | 3.9 | GO:0071206 | establishment of protein localization to juxtaparanode region of axon(GO:0071206) |
| 1.3 | 5.3 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 1.3 | 18.3 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 1.3 | 11.8 | GO:0015868 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 1.3 | 10.4 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 1.3 | 3.9 | GO:0097473 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009) |
| 1.3 | 7.8 | GO:0032571 | response to vitamin K(GO:0032571) |
| 1.3 | 5.2 | GO:0032848 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 1.3 | 5.1 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 1.3 | 11.5 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
| 1.3 | 5.1 | GO:0045404 | interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 1.3 | 25.3 | GO:0097186 | amelogenesis(GO:0097186) |
| 1.3 | 3.8 | GO:0036089 | cleavage furrow formation(GO:0036089) |
| 1.3 | 13.8 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 1.2 | 12.5 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 1.2 | 4.9 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 1.2 | 4.9 | GO:2000327 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 1.2 | 2.4 | GO:0007227 | signal transduction downstream of smoothened(GO:0007227) |
| 1.2 | 10.9 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 1.2 | 7.2 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 1.2 | 24.6 | GO:0032060 | bleb assembly(GO:0032060) |
| 1.2 | 4.7 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 1.2 | 4.7 | GO:0035962 | response to interleukin-13(GO:0035962) |
| 1.2 | 5.8 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 1.2 | 3.5 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 1.2 | 3.5 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 1.2 | 6.9 | GO:0071503 | response to heparin(GO:0071503) cellular response to heparin(GO:0071504) |
| 1.1 | 12.6 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 1.1 | 6.9 | GO:0016926 | protein desumoylation(GO:0016926) |
| 1.1 | 6.9 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 1.1 | 7.9 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 1.1 | 4.5 | GO:1904180 | negative regulation of membrane depolarization(GO:1904180) |
| 1.1 | 6.8 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 1.1 | 18.0 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 1.1 | 2.2 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) |
| 1.1 | 8.8 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 1.1 | 4.4 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 1.1 | 3.3 | GO:0035624 | receptor transactivation(GO:0035624) |
| 1.1 | 18.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 1.1 | 3.3 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584) |
| 1.1 | 5.5 | GO:0048105 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
| 1.1 | 2.2 | GO:2000863 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
| 1.1 | 8.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 1.1 | 7.5 | GO:0060694 | regulation of cholesterol transporter activity(GO:0060694) response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230) |
| 1.1 | 3.2 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 1.1 | 6.4 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 1.1 | 16.0 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 1.1 | 3.2 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 1.0 | 8.3 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 1.0 | 16.5 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 1.0 | 3.1 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 1.0 | 9.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 1.0 | 3.1 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 1.0 | 6.0 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 1.0 | 4.0 | GO:1904139 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141) |
| 1.0 | 9.0 | GO:0099638 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
| 1.0 | 9.9 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 1.0 | 5.9 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 1.0 | 4.9 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 1.0 | 8.8 | GO:0043435 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 1.0 | 3.9 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 1.0 | 1.9 | GO:1902617 | response to fluoride(GO:1902617) |
| 1.0 | 4.8 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 1.0 | 15.4 | GO:0060973 | cell migration involved in heart development(GO:0060973) |
| 1.0 | 6.7 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 1.0 | 12.4 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 1.0 | 1.9 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.9 | 25.6 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.9 | 2.8 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.9 | 2.8 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.9 | 16.0 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.9 | 0.9 | GO:0060157 | urinary bladder development(GO:0060157) |
| 0.9 | 4.7 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.9 | 2.8 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
| 0.9 | 12.9 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.9 | 2.7 | GO:1903892 | negative regulation of ATF6-mediated unfolded protein response(GO:1903892) |
| 0.9 | 2.7 | GO:0060032 | ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032) |
| 0.9 | 9.1 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.9 | 2.7 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.9 | 2.7 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.9 | 10.0 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.9 | 4.5 | GO:0001555 | oocyte growth(GO:0001555) |
| 0.9 | 3.6 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.9 | 45.0 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.9 | 22.9 | GO:0048169 | regulation of long-term neuronal synaptic plasticity(GO:0048169) |
| 0.9 | 6.1 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 0.9 | 2.6 | GO:0016103 | isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653) |
| 0.9 | 4.3 | GO:0055009 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
| 0.9 | 7.8 | GO:0042428 | serotonin metabolic process(GO:0042428) |
| 0.9 | 2.6 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.9 | 11.3 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.9 | 1.7 | GO:0010159 | specification of organ position(GO:0010159) |
| 0.9 | 12.9 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.9 | 4.3 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.9 | 2.6 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.9 | 6.0 | GO:0097354 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
| 0.9 | 6.8 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.9 | 5.1 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.8 | 11.0 | GO:0042448 | progesterone metabolic process(GO:0042448) |
| 0.8 | 1.7 | GO:1901162 | primary amino compound biosynthetic process(GO:1901162) |
| 0.8 | 24.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.8 | 3.3 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.8 | 6.6 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.8 | 2.5 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.8 | 14.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.8 | 5.8 | GO:0043307 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308) |
| 0.8 | 20.6 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.8 | 22.1 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.8 | 56.6 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.8 | 11.3 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.8 | 15.2 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.8 | 2.4 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.8 | 3.2 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.8 | 4.0 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.8 | 6.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.8 | 3.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.8 | 6.3 | GO:0019720 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.8 | 10.3 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.8 | 7.1 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.8 | 3.9 | GO:0046013 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.8 | 3.9 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.8 | 2.4 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.8 | 5.5 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.8 | 7.8 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.8 | 8.6 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.8 | 3.1 | GO:1990834 | response to odorant(GO:1990834) |
| 0.8 | 8.5 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.8 | 1.5 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 0.8 | 6.1 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
| 0.8 | 3.8 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.8 | 3.0 | GO:0019740 | regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) |
| 0.7 | 14.9 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.7 | 4.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.7 | 3.7 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.7 | 18.5 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.7 | 1.5 | GO:0050955 | thermoception(GO:0050955) |
| 0.7 | 2.2 | GO:2001033 | negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033) |
| 0.7 | 82.3 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.7 | 2.1 | GO:0030186 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219) |
| 0.7 | 7.8 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.7 | 6.3 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.7 | 9.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.7 | 6.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.7 | 4.2 | GO:0002857 | positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) |
| 0.7 | 2.1 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.7 | 8.2 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.7 | 2.7 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 0.7 | 2.7 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.7 | 2.0 | GO:0045356 | positive regulation of interferon-alpha biosynthetic process(GO:0045356) |
| 0.7 | 3.4 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
| 0.7 | 2.0 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.7 | 2.7 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
| 0.7 | 4.7 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.7 | 1.3 | GO:0090027 | negative regulation of monocyte chemotaxis(GO:0090027) |
| 0.7 | 4.6 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.7 | 6.0 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.7 | 2.6 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.7 | 29.6 | GO:0090314 | positive regulation of protein targeting to membrane(GO:0090314) |
| 0.7 | 2.0 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.7 | 12.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.7 | 1.3 | GO:0048242 | regulation of epinephrine secretion(GO:0014060) epinephrine secretion(GO:0048242) |
| 0.6 | 5.2 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.6 | 1.9 | GO:0070843 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.6 | 4.5 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.6 | 9.7 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.6 | 1.3 | GO:0072070 | cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309) loop of Henle development(GO:0072070) |
| 0.6 | 5.8 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.6 | 1.9 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 0.6 | 14.1 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.6 | 1.9 | GO:1902943 | transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) |
| 0.6 | 1.9 | GO:0036006 | response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006) |
| 0.6 | 5.0 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.6 | 6.3 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.6 | 15.6 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.6 | 4.3 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.6 | 3.7 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.6 | 6.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.6 | 3.0 | GO:2000672 | regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.6 | 12.7 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.6 | 1.8 | GO:1902473 | regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474) |
| 0.6 | 3.0 | GO:1904936 | interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.6 | 1.8 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.6 | 3.0 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.6 | 3.0 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.6 | 6.5 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.6 | 4.0 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002) |
| 0.6 | 4.0 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 0.6 | 5.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.6 | 25.9 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.6 | 22.3 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.6 | 7.8 | GO:1990123 | L-glutamate import across plasma membrane(GO:0098712) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123) |
| 0.6 | 1.1 | GO:1902573 | positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573) |
| 0.6 | 7.2 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.6 | 9.4 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
| 0.6 | 2.8 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 0.6 | 11.0 | GO:0006833 | water transport(GO:0006833) |
| 0.5 | 3.3 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.5 | 8.2 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.5 | 6.5 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.5 | 4.9 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.5 | 6.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.5 | 3.8 | GO:0046320 | regulation of fatty acid oxidation(GO:0046320) |
| 0.5 | 11.7 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.5 | 7.9 | GO:1903392 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392) |
| 0.5 | 3.1 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.5 | 8.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.5 | 10.7 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.5 | 1.5 | GO:1902462 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.5 | 1.5 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.5 | 4.0 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.5 | 4.5 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.5 | 0.5 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 0.5 | 2.4 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.5 | 3.4 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.5 | 5.3 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.5 | 2.9 | GO:0070633 | transepithelial transport(GO:0070633) |
| 0.5 | 2.9 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.5 | 2.4 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.5 | 3.3 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.5 | 1.4 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.5 | 7.6 | GO:0032366 | intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367) |
| 0.5 | 0.9 | GO:0086100 | endothelin receptor signaling pathway(GO:0086100) |
| 0.5 | 3.8 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.5 | 2.3 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.5 | 2.8 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.5 | 3.2 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 0.5 | 1.4 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.5 | 3.2 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) |
| 0.5 | 2.7 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.5 | 7.2 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
| 0.5 | 2.7 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.4 | 6.3 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.4 | 6.7 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.4 | 4.0 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.4 | 1.3 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.4 | 3.0 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.4 | 8.3 | GO:0070741 | response to interleukin-6(GO:0070741) |
| 0.4 | 1.3 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.4 | 1.7 | GO:0035815 | positive regulation of renal sodium excretion(GO:0035815) |
| 0.4 | 1.7 | GO:0030903 | notochord development(GO:0030903) |
| 0.4 | 1.3 | GO:0090009 | primitive streak formation(GO:0090009) |
| 0.4 | 4.7 | GO:0003094 | glomerular filtration(GO:0003094) |
| 0.4 | 17.0 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.4 | 3.4 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.4 | 9.7 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.4 | 5.0 | GO:0045821 | positive regulation of glycolytic process(GO:0045821) |
| 0.4 | 14.9 | GO:0007140 | male meiosis(GO:0007140) |
| 0.4 | 1.6 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.4 | 2.0 | GO:0034091 | regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) |
| 0.4 | 4.1 | GO:0051344 | negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.4 | 3.3 | GO:0086073 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.4 | 2.4 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.4 | 1.2 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 0.4 | 2.0 | GO:0060033 | anatomical structure regression(GO:0060033) |
| 0.4 | 6.4 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.4 | 3.2 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.4 | 3.5 | GO:0002042 | cell migration involved in sprouting angiogenesis(GO:0002042) |
| 0.4 | 4.3 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.4 | 3.9 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 0.4 | 2.3 | GO:0061092 | involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.4 | 16.7 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.4 | 10.2 | GO:0000732 | strand displacement(GO:0000732) |
| 0.4 | 3.8 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.4 | 22.7 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.4 | 11.9 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.4 | 12.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.4 | 1.5 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.4 | 3.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.4 | 7.3 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.4 | 2.5 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.4 | 5.4 | GO:0021978 | telencephalon regionalization(GO:0021978) |
| 0.4 | 3.9 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.4 | 7.1 | GO:0035272 | exocrine system development(GO:0035272) |
| 0.4 | 4.6 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.4 | 23.5 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.4 | 4.6 | GO:0003197 | endocardial cushion development(GO:0003197) |
| 0.4 | 7.1 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.4 | 4.2 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.4 | 0.4 | GO:0021603 | cranial nerve formation(GO:0021603) |
| 0.4 | 1.1 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.3 | 2.1 | GO:0030238 | male sex determination(GO:0030238) |
| 0.3 | 4.5 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.3 | 2.8 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.3 | 1.0 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.3 | 1.7 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.3 | 1.0 | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
| 0.3 | 5.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.3 | 1.7 | GO:0048484 | enteric nervous system development(GO:0048484) |
| 0.3 | 5.8 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.3 | 7.8 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.3 | 4.4 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.3 | 3.0 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.3 | 9.4 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.3 | 22.5 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.3 | 1.7 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.3 | 2.0 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
| 0.3 | 4.7 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.3 | 5.0 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.3 | 2.0 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.3 | 4.6 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.3 | 2.9 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.3 | 5.2 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.3 | 4.9 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 0.3 | 1.9 | GO:0051546 | keratinocyte migration(GO:0051546) |
| 0.3 | 1.9 | GO:1990035 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.3 | 6.1 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.3 | 7.0 | GO:0051567 | histone H3-K9 methylation(GO:0051567) |
| 0.3 | 6.3 | GO:1902001 | carnitine shuttle(GO:0006853) fatty acid transmembrane transport(GO:1902001) |
| 0.3 | 4.7 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.3 | 2.8 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.3 | 4.3 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.3 | 1.5 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
| 0.3 | 2.1 | GO:0060080 | inhibitory postsynaptic potential(GO:0060080) |
| 0.3 | 4.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.3 | 1.2 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.3 | 3.6 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.3 | 8.9 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.3 | 2.9 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.3 | 22.3 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.3 | 7.9 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.3 | 2.3 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.3 | 2.3 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.3 | 2.3 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.3 | 8.0 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.3 | 1.7 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.3 | 1.1 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.3 | 4.8 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.3 | 3.1 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.3 | 18.1 | GO:0009583 | detection of light stimulus(GO:0009583) |
| 0.3 | 3.3 | GO:0061154 | endothelial tube morphogenesis(GO:0061154) |
| 0.3 | 0.5 | GO:0030223 | neutrophil differentiation(GO:0030223) |
| 0.3 | 1.6 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.3 | 3.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.3 | 1.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.3 | 0.8 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.3 | 21.2 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.3 | 1.0 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.3 | 2.8 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.2 | 3.0 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.2 | 9.2 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.2 | 1.2 | GO:0043931 | ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977) |
| 0.2 | 1.7 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.2 | 1.2 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 0.7 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.2 | 0.5 | GO:0015824 | proline transport(GO:0015824) |
| 0.2 | 2.1 | GO:1904779 | regulation of protein localization to centrosome(GO:1904779) |
| 0.2 | 2.6 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.2 | 2.6 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.2 | 1.9 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.2 | 9.5 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 0.2 | 1.2 | GO:0072386 | plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.2 | 1.4 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
| 0.2 | 13.3 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.2 | 0.9 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.2 | 2.1 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.2 | 3.1 | GO:0010863 | positive regulation of phospholipase C activity(GO:0010863) |
| 0.2 | 3.6 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.2 | 1.6 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.2 | 2.2 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.2 | 2.6 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.2 | 2.4 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.2 | 6.8 | GO:0003407 | neural retina development(GO:0003407) |
| 0.2 | 1.1 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.2 | 8.8 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.2 | 11.8 | GO:0030901 | midbrain development(GO:0030901) |
| 0.2 | 32.3 | GO:0030073 | insulin secretion(GO:0030073) |
| 0.2 | 1.0 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
| 0.2 | 1.6 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.2 | 21.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.2 | 3.8 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.2 | 14.9 | GO:0008366 | ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366) |
| 0.2 | 0.8 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.2 | 5.2 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.2 | 1.6 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.2 | 1.1 | GO:1901626 | regulation of postsynaptic membrane organization(GO:1901626) |
| 0.2 | 3.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.2 | 1.9 | GO:0015801 | aromatic amino acid transport(GO:0015801) |
| 0.2 | 2.6 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.2 | 2.6 | GO:0006828 | manganese ion transport(GO:0006828) |
| 0.2 | 7.0 | GO:0008585 | female gonad development(GO:0008585) |
| 0.2 | 6.4 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.2 | 2.9 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.2 | 1.5 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.2 | 2.9 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
| 0.2 | 3.4 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.2 | 0.3 | GO:0015860 | purine nucleoside transmembrane transport(GO:0015860) |
| 0.2 | 2.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.2 | 1.1 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
| 0.2 | 15.5 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.2 | 0.6 | GO:0051410 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 0.2 | 6.5 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.2 | 1.2 | GO:0034391 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.1 | 5.2 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 5.0 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.1 | 0.7 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.1 | 0.4 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 2.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 1.8 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.1 | 3.9 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 0.1 | GO:0051389 | inactivation of MAPKK activity(GO:0051389) |
| 0.1 | 5.3 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 2.6 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
| 0.1 | 3.6 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 2.6 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.1 | 0.9 | GO:0032228 | regulation of synaptic transmission, GABAergic(GO:0032228) |
| 0.1 | 1.2 | GO:0046514 | ceramide catabolic process(GO:0046514) |
| 0.1 | 0.4 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.1 | 1.0 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.1 | 1.8 | GO:0006582 | melanin metabolic process(GO:0006582) |
| 0.1 | 0.6 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 7.7 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 2.8 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 0.5 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.1 | 14.1 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.1 | 9.1 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.1 | 1.9 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.1 | 1.6 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.1 | 0.5 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
| 0.1 | 2.2 | GO:0031670 | cellular response to nutrient(GO:0031670) |
| 0.1 | 0.4 | GO:0042090 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 0.8 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.1 | 2.8 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 1.4 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.1 | 2.6 | GO:0050766 | positive regulation of phagocytosis(GO:0050766) |
| 0.1 | 0.7 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 2.9 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.1 | 0.5 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.6 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.1 | 8.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 3.8 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.1 | 0.8 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 4.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.1 | 4.0 | GO:0042398 | cellular modified amino acid biosynthetic process(GO:0042398) |
| 0.1 | 0.8 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.1 | 0.3 | GO:0070254 | mucus secretion(GO:0070254) |
| 0.1 | 2.9 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.1 | 0.5 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 1.2 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.6 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.8 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.1 | 1.6 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 1.5 | GO:0010717 | regulation of epithelial to mesenchymal transition(GO:0010717) |
| 0.1 | 2.1 | GO:0061045 | negative regulation of wound healing(GO:0061045) |
| 0.1 | 0.9 | GO:0003170 | heart valve development(GO:0003170) |
| 0.1 | 0.8 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 1.3 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.1 | 0.3 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.0 | 1.1 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 1.0 | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 0.0 | 0.3 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 0.7 | GO:0030890 | positive regulation of B cell proliferation(GO:0030890) |
| 0.0 | 0.5 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.0 | 0.1 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.0 | 0.5 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.2 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 2.6 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 1.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 1.5 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
| 0.0 | 0.5 | GO:0061053 | somite development(GO:0061053) |
| 0.0 | 0.1 | GO:0014010 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010) |
| 0.0 | 0.5 | GO:0099514 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.3 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.0 | 0.5 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.0 | 0.3 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
| 0.0 | 0.3 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.0 | 0.7 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.0 | 0.6 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.4 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.0 | 0.0 | GO:0002583 | regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) regulation of antigen processing and presentation of peptide antigen(GO:0002583) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) |
| 0.0 | 0.3 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 0.0 | GO:0070827 | chromatin maintenance(GO:0070827) |
| 0.0 | 0.1 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 0.9 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.8 | 17.3 | GO:0036028 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 5.3 | 21.0 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 4.5 | 13.4 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 3.7 | 22.4 | GO:0045298 | tubulin complex(GO:0045298) |
| 3.0 | 6.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 3.0 | 17.9 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 2.8 | 8.4 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 2.7 | 8.0 | GO:0072563 | endothelial microparticle(GO:0072563) |
| 2.1 | 8.6 | GO:0097440 | apical dendrite(GO:0097440) |
| 2.1 | 6.4 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 2.1 | 6.4 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 2.1 | 12.7 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 2.1 | 6.3 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 2.0 | 6.0 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 1.9 | 13.6 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 1.9 | 15.3 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 1.9 | 34.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.9 | 9.4 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 1.8 | 5.4 | GO:0036398 | TCR signalosome(GO:0036398) |
| 1.7 | 31.4 | GO:0005922 | connexon complex(GO:0005922) |
| 1.7 | 18.9 | GO:0043203 | axon hillock(GO:0043203) |
| 1.7 | 8.5 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 1.6 | 14.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 1.6 | 14.2 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 1.6 | 18.9 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 1.6 | 6.3 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 1.5 | 13.9 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 1.5 | 16.1 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 1.5 | 4.4 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 1.4 | 7.2 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 1.4 | 5.8 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 1.4 | 15.6 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 1.4 | 7.1 | GO:0097513 | myosin II filament(GO:0097513) |
| 1.4 | 4.2 | GO:0071546 | pi-body(GO:0071546) |
| 1.3 | 20.2 | GO:0097433 | dense body(GO:0097433) |
| 1.3 | 4.0 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 1.3 | 10.2 | GO:0005579 | membrane attack complex(GO:0005579) |
| 1.2 | 7.3 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 1.2 | 4.8 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 1.2 | 38.1 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 1.2 | 15.4 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 1.2 | 10.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 1.2 | 4.6 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 1.1 | 18.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.1 | 28.1 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 1.1 | 5.5 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 1.1 | 5.5 | GO:0089701 | U2AF(GO:0089701) |
| 1.1 | 8.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 1.1 | 15.8 | GO:0030478 | actin cap(GO:0030478) |
| 1.0 | 5.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 1.0 | 6.0 | GO:0032584 | growth cone membrane(GO:0032584) |
| 1.0 | 5.9 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 1.0 | 7.8 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 1.0 | 13.5 | GO:0031906 | late endosome lumen(GO:0031906) |
| 1.0 | 10.5 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.9 | 2.8 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.9 | 6.6 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.9 | 4.7 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.9 | 9.1 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.9 | 17.1 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.9 | 6.3 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.9 | 13.4 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 0.9 | 5.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.9 | 4.3 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.8 | 90.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.8 | 21.0 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.8 | 8.4 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.8 | 4.9 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.8 | 5.7 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.8 | 2.4 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.8 | 13.0 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.8 | 4.8 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.8 | 2.4 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.8 | 3.9 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.7 | 8.8 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.7 | 17.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.7 | 1.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.7 | 6.7 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.7 | 2.0 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.7 | 3.9 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.6 | 3.9 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.6 | 8.2 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.6 | 28.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.6 | 3.8 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.6 | 7.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.6 | 6.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.6 | 11.0 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.6 | 3.0 | GO:1990031 | pinceau fiber(GO:1990031) |
| 0.6 | 4.8 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.6 | 3.0 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.6 | 3.6 | GO:0002177 | manchette(GO:0002177) |
| 0.6 | 3.0 | GO:0045179 | apical cortex(GO:0045179) |
| 0.6 | 10.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.6 | 1.2 | GO:0043259 | laminin-10 complex(GO:0043259) |
| 0.6 | 4.6 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.6 | 3.4 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.6 | 12.1 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.5 | 17.0 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.5 | 14.0 | GO:0043218 | compact myelin(GO:0043218) |
| 0.5 | 18.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.5 | 3.7 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.5 | 1.0 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.5 | 87.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.5 | 11.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.5 | 3.9 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.5 | 3.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.5 | 7.9 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.5 | 7.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.4 | 27.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.4 | 31.3 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.4 | 4.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.4 | 5.5 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.4 | 8.3 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.4 | 2.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.4 | 3.3 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.4 | 4.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.4 | 2.8 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 5.2 | GO:0046930 | pore complex(GO:0046930) |
| 0.4 | 11.0 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.4 | 3.1 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.4 | 2.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.4 | 11.5 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
| 0.4 | 2.2 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.4 | 13.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.4 | 4.3 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.4 | 9.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.4 | 2.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.4 | 15.5 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.3 | 9.3 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.3 | 14.0 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.3 | 7.3 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.3 | 3.0 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.3 | 3.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.3 | 5.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.3 | 44.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.3 | 32.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.3 | 2.9 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.3 | 17.3 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.3 | 110.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 3.4 | GO:0000145 | exocyst(GO:0000145) |
| 0.3 | 79.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.3 | 1.5 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.3 | 22.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.3 | 2.3 | GO:0072487 | MSL complex(GO:0072487) |
| 0.3 | 1.5 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 0.3 | 2.9 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.3 | 9.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.3 | 3.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.3 | 4.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.3 | 2.0 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.3 | 4.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.3 | 22.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.3 | 11.5 | GO:0097546 | ciliary base(GO:0097546) |
| 0.3 | 310.3 | GO:0005615 | extracellular space(GO:0005615) |
| 0.3 | 4.8 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.3 | 9.8 | GO:0005902 | microvillus(GO:0005902) |
| 0.3 | 26.3 | GO:0043204 | perikaryon(GO:0043204) |
| 0.3 | 1.8 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.3 | 1.8 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.2 | 1.2 | GO:0032010 | secondary lysosome(GO:0005767) phagolysosome(GO:0032010) |
| 0.2 | 4.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 3.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 29.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 4.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 2.7 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.2 | 2.7 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.2 | 2.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 3.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.2 | 1.1 | GO:0019814 | immunoglobulin complex(GO:0019814) |
| 0.2 | 15.0 | GO:0005776 | autophagosome(GO:0005776) |
| 0.2 | 8.8 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.2 | 6.0 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.2 | 1.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 5.3 | GO:0005901 | caveola(GO:0005901) |
| 0.2 | 12.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.2 | 37.4 | GO:0098793 | presynapse(GO:0098793) |
| 0.2 | 2.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 4.5 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.2 | 1.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.2 | 8.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 6.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.1 | 2.9 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 9.8 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.1 | 0.1 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.1 | 1.8 | GO:0031082 | BLOC complex(GO:0031082) |
| 0.1 | 16.4 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 1.9 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 180.2 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
| 0.1 | 2.1 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 0.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 2.1 | GO:0044613 | nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615) |
| 0.1 | 2.1 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 3.1 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.4 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.1 | 1.8 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 7.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 5.0 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.1 | 1.8 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.5 | GO:0043679 | axon terminus(GO:0043679) |
| 0.1 | 2.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 6.5 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 0.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 0.6 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.1 | 0.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 2.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 1.5 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 0.4 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.0 | 0.7 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 5.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 1.0 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 4.4 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 0.5 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 1.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 3.8 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 4.6 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 3.6 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 29.5 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.3 | 41.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 6.3 | 19.0 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 6.3 | 19.0 | GO:0016497 | substance K receptor activity(GO:0016497) |
| 5.7 | 22.8 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
| 5.6 | 22.4 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 5.4 | 16.2 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 5.0 | 15.0 | GO:0004507 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
| 4.6 | 4.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 3.9 | 11.7 | GO:0004336 | galactosylceramidase activity(GO:0004336) |
| 3.9 | 15.4 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 3.7 | 21.9 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 3.6 | 21.5 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 3.4 | 10.2 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 3.3 | 9.8 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 3.2 | 32.0 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 3.2 | 22.3 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 3.2 | 9.5 | GO:0008431 | vitamin E binding(GO:0008431) |
| 3.1 | 27.6 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 3.0 | 6.1 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 2.9 | 23.5 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 2.9 | 14.6 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 2.9 | 5.8 | GO:0004945 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 2.8 | 11.2 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 2.7 | 51.6 | GO:0038191 | neuropilin binding(GO:0038191) |
| 2.7 | 16.0 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 2.6 | 13.0 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 2.6 | 12.9 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 2.5 | 12.7 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 2.5 | 10.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 2.5 | 7.5 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 2.5 | 14.9 | GO:0004359 | glutaminase activity(GO:0004359) |
| 2.5 | 9.9 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 2.4 | 19.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 2.4 | 7.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 2.4 | 14.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 2.4 | 11.8 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 2.3 | 11.6 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 2.3 | 6.8 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 2.2 | 13.5 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 2.2 | 6.7 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 2.2 | 11.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 2.2 | 8.8 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 2.2 | 11.0 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 2.2 | 28.3 | GO:0036122 | BMP binding(GO:0036122) |
| 2.2 | 8.7 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 2.1 | 8.4 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 2.1 | 6.3 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 2.1 | 31.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 2.1 | 6.3 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 2.1 | 8.3 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 2.0 | 6.0 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 1.9 | 11.6 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 1.9 | 17.3 | GO:0032190 | acrosin binding(GO:0032190) |
| 1.9 | 5.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 1.8 | 7.3 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 1.8 | 14.7 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 1.8 | 9.1 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 1.8 | 12.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 1.8 | 5.4 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 1.8 | 5.3 | GO:0032093 | SAM domain binding(GO:0032093) |
| 1.8 | 5.3 | GO:0015265 | urea channel activity(GO:0015265) |
| 1.7 | 15.6 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 1.7 | 8.6 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 1.7 | 8.3 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 1.6 | 45.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 1.6 | 9.6 | GO:0030172 | troponin C binding(GO:0030172) |
| 1.6 | 12.8 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 1.6 | 6.3 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 1.6 | 20.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.6 | 4.7 | GO:0003863 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 1.5 | 9.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 1.5 | 7.5 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 1.5 | 19.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 1.5 | 7.4 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 1.5 | 4.4 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 1.5 | 13.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 1.5 | 16.2 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 1.5 | 4.4 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 1.5 | 7.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 1.5 | 31.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 1.4 | 5.7 | GO:0004513 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 1.4 | 4.2 | GO:0015403 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 1.4 | 4.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 1.4 | 4.2 | GO:0031696 | alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696) |
| 1.4 | 4.2 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 1.4 | 18.0 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 1.4 | 5.5 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 1.3 | 4.0 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 1.3 | 28.1 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 1.3 | 10.5 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 1.3 | 19.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 1.3 | 7.7 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 1.3 | 5.1 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 1.3 | 11.4 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 1.3 | 7.6 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 1.3 | 6.3 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 1.2 | 3.7 | GO:0070538 | oleic acid binding(GO:0070538) |
| 1.2 | 4.9 | GO:0038047 | beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047) |
| 1.2 | 4.9 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 1.2 | 7.2 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 1.2 | 12.0 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 1.2 | 19.1 | GO:0050693 | LBD domain binding(GO:0050693) |
| 1.2 | 17.8 | GO:0005372 | water transmembrane transporter activity(GO:0005372) |
| 1.2 | 4.7 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 1.2 | 2.3 | GO:0070905 | serine binding(GO:0070905) |
| 1.2 | 5.8 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 1.2 | 16.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 1.1 | 11.5 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 1.1 | 6.9 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 1.1 | 5.7 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.1 | 15.8 | GO:0045159 | myosin II binding(GO:0045159) |
| 1.1 | 5.6 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 1.1 | 3.4 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 1.1 | 1.1 | GO:0071553 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 1.1 | 3.3 | GO:0052835 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 1.1 | 3.3 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 1.1 | 8.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 1.1 | 6.5 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 1.1 | 14.0 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 1.1 | 6.4 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 1.1 | 4.2 | GO:0071253 | connexin binding(GO:0071253) |
| 1.1 | 9.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 1.0 | 6.3 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 1.0 | 8.3 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 1.0 | 11.4 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 1.0 | 4.1 | GO:0002046 | opsin binding(GO:0002046) |
| 1.0 | 3.1 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 1.0 | 4.1 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
| 1.0 | 5.1 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 1.0 | 3.1 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 1.0 | 102.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 1.0 | 27.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 1.0 | 3.9 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 1.0 | 5.9 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 1.0 | 15.7 | GO:0019841 | retinol binding(GO:0019841) |
| 1.0 | 4.9 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 1.0 | 2.9 | GO:0052816 | medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816) |
| 1.0 | 2.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 1.0 | 11.6 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 1.0 | 2.9 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.9 | 8.5 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.9 | 42.5 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.9 | 1.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.9 | 2.8 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.9 | 9.1 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.9 | 7.3 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.9 | 2.7 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.9 | 7.2 | GO:0043426 | MRF binding(GO:0043426) |
| 0.9 | 7.2 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.9 | 9.7 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.9 | 2.6 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.9 | 6.0 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.9 | 3.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.9 | 2.6 | GO:0042806 | fucose binding(GO:0042806) |
| 0.9 | 7.7 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.8 | 5.9 | GO:0004797 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.8 | 11.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.8 | 10.0 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.8 | 3.3 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.8 | 6.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.8 | 4.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.8 | 10.7 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.8 | 18.0 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.8 | 43.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.8 | 14.6 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.8 | 2.4 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.8 | 4.0 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 0.8 | 4.0 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.8 | 3.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.8 | 2.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.8 | 5.5 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.8 | 6.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.8 | 3.1 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.8 | 9.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.8 | 16.1 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.8 | 65.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.8 | 5.3 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.8 | 3.0 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.7 | 12.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.7 | 4.4 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.7 | 7.3 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.7 | 6.5 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.7 | 3.6 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.7 | 2.1 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.7 | 8.5 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.7 | 3.5 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.7 | 9.2 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.7 | 6.3 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.7 | 9.1 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.7 | 197.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.7 | 2.8 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.7 | 9.6 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.7 | 2.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.7 | 12.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.7 | 6.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.7 | 10.8 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.7 | 1.3 | GO:0033265 | choline binding(GO:0033265) |
| 0.7 | 4.7 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.7 | 2.7 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 0.7 | 4.7 | GO:0005497 | androgen binding(GO:0005497) |
| 0.7 | 40.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.7 | 2.0 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.7 | 7.2 | GO:0019864 | IgG binding(GO:0019864) |
| 0.7 | 2.0 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.7 | 2.0 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
| 0.7 | 3.3 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.7 | 3.3 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.7 | 6.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.6 | 1.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.6 | 2.6 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.6 | 2.6 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.6 | 20.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.6 | 2.6 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
| 0.6 | 6.4 | GO:0038187 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.6 | 1.3 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.6 | 2.6 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 0.6 | 1.9 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.6 | 1.9 | GO:0005011 | macrophage colony-stimulating factor receptor activity(GO:0005011) |
| 0.6 | 5.0 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.6 | 12.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.6 | 1.8 | GO:0016803 | ether hydrolase activity(GO:0016803) hepoxilin-epoxide hydrolase activity(GO:0047977) |
| 0.6 | 37.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.6 | 2.4 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
| 0.6 | 3.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.6 | 4.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.6 | 9.2 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.6 | 2.8 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.6 | 7.2 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.6 | 7.2 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.6 | 3.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.5 | 1.6 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.5 | 7.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.5 | 2.2 | GO:0035473 | lipase binding(GO:0035473) |
| 0.5 | 4.8 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.5 | 2.1 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.5 | 2.6 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.5 | 4.7 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.5 | 7.3 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.5 | 17.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.5 | 13.8 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.5 | 2.6 | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.5 | 21.0 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.5 | 3.6 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.5 | 2.0 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.5 | 11.6 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.5 | 1.5 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.5 | 3.0 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.5 | 9.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.5 | 5.9 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.5 | 8.6 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.5 | 26.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.5 | 5.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.5 | 11.0 | GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645) |
| 0.5 | 12.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.5 | 1.9 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.5 | 11.8 | GO:0030169 | hyaluronic acid binding(GO:0005540) low-density lipoprotein particle binding(GO:0030169) |
| 0.5 | 12.2 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.5 | 3.7 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.5 | 3.3 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.5 | 11.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.5 | 11.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.5 | 1.8 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.5 | 15.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.4 | 2.2 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.4 | 8.3 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.4 | 5.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.4 | 4.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.4 | 4.3 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.4 | 3.0 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.4 | 1.7 | GO:0043273 | CTPase activity(GO:0043273) |
| 0.4 | 5.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.4 | 3.7 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.4 | 2.9 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.4 | 2.5 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.4 | 5.7 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.4 | 4.0 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.4 | 3.2 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.4 | 2.8 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.4 | 7.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.4 | 12.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.4 | 5.0 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.4 | 5.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.4 | 1.5 | GO:0032406 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.4 | 3.1 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.4 | 15.7 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.4 | 3.7 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.4 | 0.7 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.4 | 1.5 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.4 | 1.5 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.4 | 4.3 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.4 | 7.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.4 | 20.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.4 | 3.6 | GO:0005549 | odorant binding(GO:0005549) |
| 0.3 | 1.7 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.3 | 4.5 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.3 | 1.0 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 0.3 | 2.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.3 | 4.1 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.3 | 15.2 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.3 | 12.9 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
| 0.3 | 6.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.3 | 2.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.3 | 4.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.3 | 1.9 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.3 | 18.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.3 | 4.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.3 | 1.6 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.3 | 3.1 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.3 | 1.9 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.3 | 4.0 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.3 | 4.3 | GO:0055102 | phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102) |
| 0.3 | 17.2 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.3 | 33.7 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.3 | 2.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.3 | 0.6 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.3 | 2.7 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.3 | 0.6 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.3 | 1.5 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 0.3 | 2.6 | GO:0070679 | store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.3 | 7.1 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.3 | 0.9 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.3 | 2.8 | GO:0051184 | cofactor transporter activity(GO:0051184) |
| 0.3 | 8.5 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.3 | 9.0 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.3 | 1.1 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.3 | 3.0 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.3 | 9.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.3 | 8.6 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.3 | 0.5 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.3 | 20.1 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.3 | 5.3 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.3 | 2.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.3 | 6.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.3 | 2.3 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.3 | 1.8 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.3 | 14.8 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.3 | 4.5 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.3 | 0.8 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.2 | 4.0 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.2 | 1.5 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.2 | 2.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 3.4 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.2 | 0.7 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
| 0.2 | 6.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 5.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 0.7 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 25.9 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.2 | 5.3 | GO:0019840 | isoprenoid binding(GO:0019840) |
| 0.2 | 3.9 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.2 | 1.4 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.2 | 21.2 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.2 | 3.8 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 1.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.2 | 9.5 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 6.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.2 | 13.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.2 | 4.1 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.2 | 1.8 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 1.4 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.2 | 6.3 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.2 | 3.2 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.2 | 3.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.2 | 0.7 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.2 | 3.1 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.2 | 0.7 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.2 | 0.5 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
| 0.2 | 1.7 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.2 | 3.5 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.2 | 6.3 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.2 | 24.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 0.6 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) |
| 0.2 | 1.0 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.2 | 1.7 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.2 | 18.7 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.1 | 0.6 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.1 | 5.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 1.5 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 4.6 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 1.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 2.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 6.0 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 3.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 10.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 4.1 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 0.8 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.1 | 7.2 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 0.5 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 1.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 1.5 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.1 | GO:0010851 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
| 0.1 | 0.9 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 0.6 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 10.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 3.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 3.9 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.3 | GO:0015389 | pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 0.1 | 6.6 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.1 | 10.3 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.1 | 2.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 4.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 1.0 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 0.4 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.1 | 8.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 3.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 2.3 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 1.0 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.1 | 1.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 1.7 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.1 | 0.6 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 1.1 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 1.2 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 1.5 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 0.9 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 1.1 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 27.7 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.9 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.7 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 4.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 3.2 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.9 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.3 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.0 | 0.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 1.1 | GO:0005261 | cation channel activity(GO:0005261) |
| 0.0 | 0.7 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.5 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.7 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.3 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.0 | 0.5 | GO:0070851 | growth factor receptor binding(GO:0070851) |
| 0.0 | 0.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.1 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.0 | 0.1 | GO:0030884 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.0 | 0.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 76.2 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 1.0 | 14.9 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.9 | 16.4 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.9 | 17.1 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.8 | 33.2 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.8 | 13.2 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.8 | 18.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.8 | 4.9 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.8 | 58.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.7 | 33.4 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.7 | 21.1 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.7 | 24.6 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.7 | 4.9 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.6 | 3.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.6 | 4.4 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.6 | 9.7 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.6 | 44.6 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.6 | 3.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.6 | 100.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.6 | 10.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.6 | 9.9 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.5 | 197.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.5 | 17.0 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.5 | 15.6 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.5 | 6.7 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.5 | 8.5 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.5 | 13.5 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.5 | 6.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.4 | 23.3 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.4 | 27.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.4 | 2.1 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.4 | 13.9 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.4 | 103.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 13.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 2.4 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.3 | 9.3 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.3 | 11.4 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.3 | 2.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.3 | 2.6 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.3 | 2.2 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.3 | 7.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.3 | 14.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.3 | 4.6 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.3 | 1.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.3 | 59.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 1.9 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.3 | 11.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 0.7 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.2 | 1.0 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.2 | 10.1 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.2 | 4.3 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.2 | 11.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 5.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.2 | 7.5 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 6.1 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.2 | 2.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 12.1 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.2 | 5.8 | PID FGF PATHWAY | FGF signaling pathway |
| 0.2 | 5.5 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.2 | 7.0 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.2 | 7.1 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.2 | 3.8 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.2 | 4.7 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.2 | 2.8 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.2 | 3.4 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.2 | 5.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 5.6 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 3.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 4.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 3.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 1.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 3.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 5.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 1.1 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 2.6 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.1 | 3.3 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 2.9 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 1.8 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 1.6 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.1 | 1.4 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 4.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 2.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 3.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.4 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.5 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 1.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.4 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.4 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 8.2 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 2.1 | 27.1 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 1.7 | 31.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 1.6 | 39.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 1.6 | 31.4 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 1.4 | 2.9 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 1.4 | 17.8 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 1.3 | 22.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 1.2 | 17.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 1.2 | 38.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 1.2 | 17.6 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 1.2 | 18.7 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 1.1 | 24.0 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 1.0 | 30.1 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 1.0 | 4.8 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 1.0 | 32.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.9 | 9.4 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.9 | 6.5 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.9 | 14.6 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.9 | 18.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.9 | 23.2 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.9 | 20.3 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.8 | 16.1 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.8 | 2.5 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.8 | 8.1 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.8 | 15.9 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.8 | 16.9 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.8 | 2.3 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.7 | 8.1 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.7 | 6.6 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.7 | 23.9 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.7 | 40.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.7 | 27.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.6 | 12.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.6 | 40.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.6 | 7.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.6 | 9.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.6 | 124.0 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.6 | 10.8 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.6 | 8.3 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.6 | 1.2 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.6 | 30.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.5 | 8.7 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.5 | 11.7 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.5 | 20.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.5 | 4.0 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.5 | 2.4 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.5 | 6.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.4 | 9.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.4 | 10.0 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.4 | 16.5 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.4 | 45.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.4 | 3.0 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.4 | 13.6 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.4 | 15.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.4 | 13.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.4 | 4.5 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.4 | 9.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.4 | 4.0 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.4 | 7.4 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.4 | 17.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.4 | 2.7 | REACTOME PRE NOTCH EXPRESSION AND PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.4 | 16.7 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.4 | 1.5 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.4 | 7.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.4 | 6.0 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.3 | 11.1 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.3 | 4.8 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.3 | 17.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.3 | 10.2 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.3 | 2.0 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.3 | 6.7 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.3 | 4.7 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.3 | 4.9 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.3 | 5.0 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.3 | 4.4 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.2 | 23.1 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.2 | 9.7 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.2 | 18.7 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.2 | 29.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 2.7 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.2 | 0.9 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.2 | 3.5 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 3.1 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.2 | 4.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.2 | 7.5 | REACTOME SIGNALING BY NOTCH | Genes involved in Signaling by NOTCH |
| 0.2 | 11.1 | REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS | Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events |
| 0.2 | 6.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.2 | 4.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 4.7 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.2 | 4.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.2 | 3.6 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.2 | 2.1 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.2 | 5.2 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.2 | 20.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.2 | 3.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.2 | 3.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.2 | 4.3 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.2 | 3.8 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.2 | 3.8 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 1.4 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 2.8 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 0.4 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 3.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 1.2 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 3.6 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 3.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 3.5 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 5.0 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 1.6 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 6.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 3.7 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.1 | 2.9 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 16.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 9.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 2.6 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.1 | 1.8 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.1 | 2.8 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 1.3 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 3.1 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.0 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.1 | 2.8 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 0.9 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 1.0 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 0.1 | 4.1 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 0.5 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.1 | 0.4 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 3.2 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.6 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.2 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 1.3 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.5 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.5 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 2.3 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.5 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.5 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |