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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HIC2

Z-value: 7.76

Motif logo

Transcription factors associated with HIC2

Gene Symbol Gene ID Gene Info
ENSG00000169635.10 HIC2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIC2hg38_v1_chr22_+_21420636_214206690.203.8e-03Click!

Activity profile of HIC2 motif

Sorted Z-values of HIC2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_7091873 31.17 ENST00000538050.5
ENST00000536053.6
complement C1r
chr12_-_14885845 28.94 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr22_+_32801697 26.04 ENST00000266085.7
TIMP metallopeptidase inhibitor 3
chr12_-_7092422 24.96 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr13_+_41457543 24.00 ENST00000379359.4
regulator of cell cycle
chr9_+_136977496 23.22 ENST00000371625.8
ENST00000457950.5
prostaglandin D2 synthase
chr4_+_25160631 21.47 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr11_-_5227063 21.00 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr10_+_122461545 19.61 ENST00000368984.8
HtrA serine peptidase 1
chr17_+_1771688 18.92 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr14_-_94390650 18.46 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr11_-_66317037 18.27 ENST00000311330.4
CD248 molecule
chr6_-_73452124 17.07 ENST00000680833.1
cyclic GMP-AMP synthase
chr14_-_94390667 16.76 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr4_-_1208825 16.63 ENST00000511679.5
ENST00000617421.4
spondin 2
chr16_-_67980483 16.45 ENST00000268793.6
ENST00000672962.1
dipeptidase 3
chr14_-_94390614 16.39 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr1_-_119768892 16.25 ENST00000369406.8
ENST00000544913.2
3-hydroxy-3-methylglutaryl-CoA synthase 2
chrX_+_153056458 16.19 ENST00000593810.3
PNMA family member 3
chr19_+_35138993 16.00 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr10_+_86968432 15.79 ENST00000416348.1
ENST00000372013.8
adipogenesis regulatory factor
chr9_+_121268060 15.76 ENST00000373808.8
ENST00000432226.7
ENST00000449733.7
gelsolin
chr10_-_69409275 15.74 ENST00000373307.5
tachykinin receptor 2
chr9_+_136980211 15.64 ENST00000444903.2
prostaglandin D2 synthase
chrX_-_17860707 15.17 ENST00000360011.5
retinoic acid induced 2
chr16_+_58463663 15.07 ENST00000258187.9
NDRG family member 4
chrX_+_153056408 14.81 ENST00000619635.1
PNMA family member 3
chr17_-_28576882 14.67 ENST00000395319.7
ENST00000581807.5
ENST00000226253.9
ENST00000584086.5
ENST00000395321.6
aldolase, fructose-bisphosphate C
chr11_-_2140967 14.27 ENST00000381389.5
insulin like growth factor 2
chr15_-_82647503 14.16 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr8_-_27614681 14.15 ENST00000519472.5
ENST00000523589.5
ENST00000522413.5
ENST00000523396.1
ENST00000316403.15
clusterin
chr3_+_50273119 14.08 ENST00000456560.6
ENST00000418576.3
semaphorin 3B
chr11_-_111912871 14.05 ENST00000528628.5
crystallin alpha B
chr2_+_20447065 13.98 ENST00000272233.6
ras homolog family member B
chr1_-_153070840 13.82 ENST00000368755.2
small proline rich protein 2B
chr3_+_50267606 13.66 ENST00000618865.4
semaphorin 3B
chr10_-_88952763 13.43 ENST00000224784.10
actin alpha 2, smooth muscle
chr2_+_99141696 13.31 ENST00000650052.2
ENST00000409684.2
chromosome 2 open reading frame 15
chr19_+_50203607 13.29 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr1_+_25616780 13.28 ENST00000374332.9
mannosidase alpha class 1C member 1
chr16_+_84294823 13.13 ENST00000568638.1
WAP four-disulfide core domain 1
chr11_-_2149603 12.98 ENST00000643349.1
novel protein
chr14_-_20802836 12.96 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr9_-_121370275 12.86 ENST00000538954.5
stomatin
chr18_+_74148508 12.83 ENST00000580087.5
ENST00000169551.11
translocase of inner mitochondrial membrane 21
chr12_+_53050179 12.74 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr22_+_22900976 12.70 ENST00000390323.2
immunoglobulin lambda constant 2
chr17_+_18315273 12.69 ENST00000406438.5
SMCR8-C9orf72 complex subunit
chr11_+_17734732 12.67 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr17_-_17972374 12.64 ENST00000318094.14
ENST00000540946.5
ENST00000379504.8
ENST00000542206.5
ENST00000395739.8
ENST00000581396.5
ENST00000535933.5
ENST00000579586.1
target of myb1 like 2 membrane trafficking protein
chr17_+_39927724 12.52 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr14_-_100568475 12.48 ENST00000553553.6
brain enriched guanylate kinase associated
chr3_+_148739798 12.43 ENST00000402260.2
angiotensin II receptor type 1
chr19_+_859654 12.41 ENST00000592860.2
ENST00000327726.11
complement factor D
chrX_+_7147675 12.37 ENST00000674429.1
steroid sulfatase
chr6_-_166627244 12.23 ENST00000265678.9
ribosomal protein S6 kinase A2
chr9_-_33264559 12.10 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG cochaperone 1
chr9_-_90642855 11.87 ENST00000637905.1
DIRAS family GTPase 2
chr19_+_17871937 11.85 ENST00000222248.4
solute carrier family 5 member 5
chr17_+_45894515 11.80 ENST00000680674.1
ENST00000535772.6
ENST00000351559.10
ENST00000262410.10
ENST00000344290.10
microtubule associated protein tau
chr11_-_65117639 11.80 ENST00000528598.1
ENST00000310597.6
zinc finger HIT-type containing 2
chr13_-_36920227 11.77 ENST00000379826.5
ENST00000350148.10
SMAD family member 9
chr9_-_34710069 11.76 ENST00000378792.1
ENST00000259607.7
C-C motif chemokine ligand 21
chr11_-_2141238 11.58 ENST00000434045.6
insulin like growth factor 2
chr16_+_84294853 11.48 ENST00000219454.10
WAP four-disulfide core domain 1
chr12_+_53050014 11.45 ENST00000314250.11
tensin 2
chr11_-_66568524 11.44 ENST00000679160.1
ENST00000678305.1
ENST00000310325.10
ENST00000677896.1
ENST00000677587.1
ENST00000679347.1
ENST00000677005.1
ENST00000678872.1
ENST00000679024.1
ENST00000678471.1
ENST00000524994.6
cathepsin F
chr6_+_121437378 11.44 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr5_-_135578983 11.21 ENST00000512158.6
C-X-C motif chemokine ligand 14
chr11_+_72216774 11.16 ENST00000619261.4
ENST00000454954.6
ENST00000541003.5
ENST00000539412.5
ENST00000298223.11
ENST00000536778.5
ENST00000535625.5
ENST00000321324.11
folate receptor beta
chr15_+_40953463 11.11 ENST00000617768.5
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr17_-_7294592 11.06 ENST00000007699.10
Y-box binding protein 2
chr22_-_18936142 10.95 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr19_+_18683656 10.94 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chr1_+_160115715 10.94 ENST00000361216.8
ATPase Na+/K+ transporting subunit alpha 2
chr6_-_52763473 10.91 ENST00000493422.3
glutathione S-transferase alpha 2
chr6_+_31586859 10.90 ENST00000433492.5
leukocyte specific transcript 1
chr1_-_1574551 10.86 ENST00000359060.5
SSU72 homolog, RNA polymerase II CTD phosphatase
chr1_+_32539418 10.86 ENST00000373510.9
ENST00000316459.4
zinc finger and BTB domain containing 8A
chr17_+_42853232 10.82 ENST00000617500.4
amine oxidase copper containing 3
chr17_+_45894644 10.62 ENST00000680542.1
ENST00000334239.12
ENST00000446361.7
microtubule associated protein tau
chr9_-_23821275 10.61 ENST00000380110.8
ELAV like RNA binding protein 2
chr8_-_142614469 10.56 ENST00000356613.4
activity regulated cytoskeleton associated protein
chr17_-_76570544 10.55 ENST00000640006.1
novel protein
chr1_+_210328894 10.54 ENST00000261458.8
ENST00000537898.5
ENST00000545154.5
hedgehog acyltransferase
chr6_-_46325641 10.51 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr10_-_93601228 10.50 ENST00000371464.8
retinol binding protein 4
chr3_+_46880242 10.46 ENST00000418619.5
parathyroid hormone 1 receptor
chrX_+_7147819 10.45 ENST00000660000.2
steroid sulfatase
chr3_+_32106612 10.38 ENST00000282541.10
ENST00000425459.5
ENST00000431009.1
glycerol-3-phosphate dehydrogenase 1 like
chr12_-_52520371 10.36 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr19_+_47256518 10.27 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chr10_+_38010617 10.25 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr11_+_46701010 10.22 ENST00000311764.3
zinc finger protein 408
chr8_+_119873710 10.21 ENST00000523492.5
ENST00000286234.6
DEP domain containing MTOR interacting protein
chr17_-_18314956 10.20 ENST00000321105.10
ENST00000542570.5
DNA topoisomerase III alpha
chr11_+_117199363 10.20 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr6_-_73452253 10.11 ENST00000370318.5
ENST00000370315.4
cyclic GMP-AMP synthase
chr15_+_74826603 10.08 ENST00000395018.6
complexin 3
chrX_-_49200174 10.07 ENST00000472598.5
ENST00000263233.9
ENST00000479808.5
synaptophysin
chrX_+_123859976 10.06 ENST00000371199.8
X-linked inhibitor of apoptosis
chr3_+_50269140 10.04 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr19_-_13906062 10.04 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr2_+_200440649 9.92 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr9_+_98943898 9.91 ENST00000375001.8
collagen type XV alpha 1 chain
chr14_-_103522696 9.90 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr6_-_119078642 9.84 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr8_-_47738153 9.80 ENST00000408965.4
CCAAT enhancer binding protein delta
chr17_+_4807119 9.77 ENST00000263088.11
ENST00000572940.5
phospholipase D2
chr1_-_19979607 9.70 ENST00000400520.8
ENST00000482011.2
ENST00000649436.1
phospholipase A2 group IIA
chr17_-_7916280 9.69 ENST00000324348.9
ring finger protein 227
chr12_+_40692413 9.66 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr2_-_135531172 9.65 ENST00000264159.11
zinc finger RANBP2-type containing 3
chr8_-_142917843 9.59 ENST00000323110.2
cytochrome P450 family 11 subfamily B member 2
chr14_+_100726883 9.57 ENST00000341267.9
ENST00000331224.10
ENST00000556051.1
delta like non-canonical Notch ligand 1
chr10_+_46579084 9.57 ENST00000512997.5
ENST00000374321.9
ENST00000503753.5
synaptotagmin 15
chr8_-_98294195 9.53 ENST00000430223.7
NIPA like domain containing 2
chr19_-_45322867 9.53 ENST00000221476.4
creatine kinase, M-type
chr22_+_30396991 9.53 ENST00000617837.4
ENST00000615189.5
ENST00000405717.7
ENST00000402592.7
SEC14 like lipid binding 2
chr9_-_121370235 9.52 ENST00000286713.7
ENST00000347359.3
stomatin
chr19_+_17215716 9.51 ENST00000593597.1
unconventional SNARE in the ER 1
chr7_+_94394886 9.47 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr3_+_48989876 9.39 ENST00000343546.8
prolyl 4-hydroxylase, transmembrane
chr11_+_73646558 9.38 ENST00000536527.5
ENST00000354190.10
pleckstrin homology domain containing B1
chr9_-_127715633 9.37 ENST00000335223.5
ENST00000416214.1
ENST00000543175.5
peptidyl-tRNA hydrolase 1 homolog
chr3_+_51391250 9.36 ENST00000563281.2
RNA binding motif protein 15B
chr19_+_16719841 9.32 ENST00000524140.7
NACHT and WD repeat domain containing 1
chr19_-_40414785 9.28 ENST00000674005.2
periaxin
chr3_+_184186023 9.27 ENST00000429586.6
ENST00000292808.5
ATP binding cassette subfamily F member 3
chr17_+_39665340 9.26 ENST00000578283.1
ENST00000309889.3
titin-cap
chr1_-_11805924 9.25 ENST00000418034.1
methylenetetrahydrofolate reductase
chr1_-_230745574 9.24 ENST00000681269.1
angiotensinogen
chr3_-_58627596 9.23 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chrX_+_71215156 9.22 ENST00000374029.2
ENST00000675209.1
ENST00000647424.1
ENST00000675368.1
ENST00000675609.1
ENST00000646835.1
ENST00000447581.2
gap junction protein beta 1
chr19_+_45079195 9.19 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr15_-_65211463 9.17 ENST00000261883.6
cartilage intermediate layer protein
chr3_+_52495330 9.14 ENST00000321725.10
stabilin 1
chrX_-_108736556 9.11 ENST00000372129.4
insulin receptor substrate 4
chr11_-_46700567 9.06 ENST00000311956.9
Rho GTPase activating protein 1
chr14_+_94581388 9.03 ENST00000554866.5
ENST00000556775.5
serpin family A member 5
chr4_+_88592426 9.02 ENST00000431413.5
ENST00000402738.6
ENST00000422770.5
ENST00000407637.5
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr3_-_14540315 9.01 ENST00000621039.5
glutamate receptor interacting protein 2
chrX_+_18425597 8.95 ENST00000623535.2
ENST00000674046.1
cyclin dependent kinase like 5
chr1_-_237004440 8.92 ENST00000464121.3
metallothionein 1H like 1
chr7_-_22356914 8.91 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr15_+_70892443 8.88 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr19_+_40191410 8.83 ENST00000253055.8
mitogen-activated protein kinase kinase kinase 10
chr22_-_50582785 8.83 ENST00000406938.3
choline kinase beta
chr9_-_23821809 8.76 ENST00000544538.5
ELAV like RNA binding protein 2
chr19_+_16720004 8.75 ENST00000673803.1
ENST00000549814.5
NACHT and WD repeat domain containing 1
chr5_-_141682211 8.71 ENST00000239440.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_-_110607425 8.69 ENST00000633222.1
potassium voltage-gated channel subfamily A member 2
chr1_+_52142044 8.67 ENST00000287727.8
ENST00000371591.2
zinc finger FYVE-type containing 9
chr1_-_6180265 8.66 ENST00000262450.8
chromodomain helicase DNA binding protein 5
chr15_-_74367637 8.66 ENST00000268053.11
ENST00000416978.1
cytochrome P450 family 11 subfamily A member 1
chr16_-_55833186 8.60 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr8_+_141413316 8.51 ENST00000329397.6
protein tyrosine phosphatase 4A3
chr5_-_116536458 8.51 ENST00000510263.5
semaphorin 6A
chr14_-_105743032 8.50 ENST00000390548.6
ENST00000390549.6
ENST00000390542.6
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_-_31346143 8.49 ENST00000405309.7
ENST00000351933.8
POZ/BTB and AT hook containing zinc finger 1
chr1_+_32205657 8.46 ENST00000291358.11
ENST00000537469.2
IQ motif containing C
chr18_+_31591869 8.42 ENST00000237014.8
transthyretin
chrX_+_123859807 8.38 ENST00000434753.7
ENST00000430625.1
X-linked inhibitor of apoptosis
chr10_-_102837406 8.34 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chr9_-_87974667 8.29 ENST00000375883.7
cyclin dependent kinase 20
chr7_+_73328177 8.27 ENST00000442793.5
ENST00000413573.6
FKBP prolyl isomerase family member 6 (inactive)
chr22_+_30635746 8.25 ENST00000343605.5
solute carrier family 35 member E4
chr14_+_94581407 8.25 ENST00000553511.1
ENST00000329597.12
ENST00000554633.5
ENST00000555681.1
ENST00000554276.1
serpin family A member 5
chrX_+_43656289 8.24 ENST00000338702.4
monoamine oxidase A
chr8_-_31033582 8.22 ENST00000339382.3
ENST00000475541.2
purine rich element binding protein G
chr16_+_67164730 8.20 ENST00000521374.6
heat shock transcription factor 4
chr1_-_110607307 8.19 ENST00000639048.2
ENST00000675391.1
ENST00000639233.2
potassium voltage-gated channel subfamily A member 2
chr10_-_98030612 8.19 ENST00000370597.8
cartilage acidic protein 1
chr7_+_43112593 8.16 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr22_-_37019434 8.13 ENST00000249042.8
ENST00000403892.7
thiosulfate sulfurtransferase
chrX_-_17861236 8.13 ENST00000331511.5
ENST00000415486.7
ENST00000451717.6
ENST00000545871.1
retinoic acid induced 2
chr16_+_67164780 8.13 ENST00000517685.5
ENST00000584272.5
heat shock transcription factor 4
chr16_+_30374794 8.11 ENST00000322861.12
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_-_33264678 8.10 ENST00000635077.1
ENST00000634734.3
BAG cochaperone 1
chr15_-_82647960 8.10 ENST00000615198.4
cytoplasmic polyadenylation element binding protein 1
chr1_-_173824107 8.10 ENST00000345664.10
ENST00000367710.7
centromere protein L
chr8_+_22057857 8.09 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr8_+_133113483 8.04 ENST00000521107.1
thyroglobulin
chr4_-_120922648 8.03 ENST00000264808.8
PR/SET domain 5
chr1_-_163202835 8.02 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chr1_+_121184964 8.00 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chrX_-_132489954 7.97 ENST00000370844.5
muscleblind like splicing regulator 3
chr9_-_127854636 7.97 ENST00000344849.4
ENST00000373203.9
endoglin
chr11_-_104164361 7.95 ENST00000302251.9
platelet derived growth factor D
chr14_-_103847487 7.93 ENST00000553739.2
ENST00000202556.14
protein phosphatase 1 regulatory subunit 13B
chr19_-_49813223 7.90 ENST00000533418.5
fuzzy planar cell polarity protein
chr16_-_65121930 7.84 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
cadherin 11
chr9_+_36036899 7.80 ENST00000377966.4
reversion inducing cysteine rich protein with kazal motifs
chr19_+_35030711 7.78 ENST00000595652.5
sodium voltage-gated channel beta subunit 1
chrX_-_30308333 7.75 ENST00000378963.1
nuclear receptor subfamily 0 group B member 1
chr20_+_23035312 7.74 ENST00000255008.5
somatostatin receptor 4
chr7_+_139231225 7.74 ENST00000473989.8
ubinuclein 2
chr19_-_8514146 7.73 ENST00000255616.8
ENST00000393927.9
zinc finger protein 414
chr5_-_160312524 7.72 ENST00000520748.1
ENST00000257536.13
ENST00000393977.7
cyclin J like
chr1_-_46941425 7.71 ENST00000371904.8
cytochrome P450 family 4 subfamily A member 11

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 33.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
7.7 30.9 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
7.0 21.0 GO:0030185 nitric oxide transport(GO:0030185)
5.1 20.4 GO:0090301 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
5.0 14.9 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
4.8 19.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
4.6 13.9 GO:0019075 virus maturation(GO:0019075)
4.5 22.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
4.5 17.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
3.9 19.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
3.9 11.8 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
3.9 11.7 GO:0006683 galactosylceramide catabolic process(GO:0006683)
3.8 19.0 GO:0035106 operant conditioning(GO:0035106)
3.7 11.1 GO:0009386 translational attenuation(GO:0009386)
3.7 21.9 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
3.7 11.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
3.6 10.9 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
3.6 10.9 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
3.6 14.6 GO:0003095 pressure natriuresis(GO:0003095)
3.6 7.3 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
3.6 10.8 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
3.6 14.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
3.6 10.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
3.5 10.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
3.5 17.3 GO:0061107 seminal vesicle development(GO:0061107)
3.4 13.6 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
3.4 20.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
3.4 16.9 GO:0090131 mesenchyme migration(GO:0090131)
3.4 23.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
3.3 13.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
3.2 9.7 GO:0036292 DNA rewinding(GO:0036292)
3.2 9.6 GO:0009720 detection of hormone stimulus(GO:0009720)
3.2 22.4 GO:0070560 protein secretion by platelet(GO:0070560)
3.2 12.7 GO:0021759 globus pallidus development(GO:0021759)
3.2 15.8 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.1 6.3 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
3.1 9.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769)
3.1 12.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.1 12.2 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
3.0 9.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.9 11.7 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
2.9 23.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.9 11.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.8 2.8 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
2.8 14.1 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.8 19.7 GO:0034587 piRNA metabolic process(GO:0034587)
2.8 28.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
2.8 2.8 GO:0071288 cellular response to mercury ion(GO:0071288)
2.7 5.4 GO:0060435 bronchiole development(GO:0060435)
2.7 8.0 GO:0001300 chronological cell aging(GO:0001300)
2.6 7.8 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
2.6 5.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
2.5 7.5 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
2.5 7.5 GO:0042412 taurine biosynthetic process(GO:0042412)
2.4 7.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
2.4 12.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
2.4 7.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
2.4 11.8 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
2.4 14.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
2.4 9.5 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.4 4.7 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
2.3 13.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
2.3 9.1 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
2.3 18.1 GO:0015705 iodide transport(GO:0015705)
2.2 6.7 GO:0019046 release from viral latency(GO:0019046)
2.2 6.7 GO:1904640 response to methionine(GO:1904640)
2.2 6.7 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.2 26.3 GO:0030321 transepithelial chloride transport(GO:0030321)
2.2 17.4 GO:0072719 cellular response to cisplatin(GO:0072719)
2.2 13.0 GO:0006543 glutamine catabolic process(GO:0006543)
2.1 6.4 GO:0008355 olfactory learning(GO:0008355)
2.1 6.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
2.1 4.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.1 10.6 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
2.1 12.6 GO:0071105 response to interleukin-11(GO:0071105)
2.1 14.6 GO:0086017 Purkinje myocyte action potential(GO:0086017) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
2.1 12.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
2.1 6.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
2.1 8.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.0 12.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
2.0 6.0 GO:0048570 notochord morphogenesis(GO:0048570)
2.0 42.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.0 6.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
2.0 9.9 GO:0044375 regulation of peroxisome size(GO:0044375)
2.0 19.6 GO:0021633 optic nerve structural organization(GO:0021633)
1.9 7.8 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
1.9 13.6 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
1.9 9.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.9 21.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.9 7.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
1.9 11.3 GO:0018343 protein farnesylation(GO:0018343)
1.9 5.6 GO:0001757 somite specification(GO:0001757)
1.9 5.6 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.8 5.5 GO:0060086 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.8 7.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.8 9.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.8 7.3 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
1.8 5.4 GO:0030035 microspike assembly(GO:0030035)
1.8 12.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.8 5.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.8 12.4 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
1.8 3.5 GO:0035973 aggrephagy(GO:0035973)
1.8 1.8 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
1.8 5.3 GO:0007538 primary sex determination(GO:0007538)
1.7 8.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
1.7 3.4 GO:0060513 prostatic bud formation(GO:0060513)
1.7 5.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
1.7 5.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
1.7 8.5 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.7 15.2 GO:0035865 cellular response to potassium ion(GO:0035865)
1.7 10.1 GO:0021553 olfactory nerve development(GO:0021553)
1.7 5.0 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.6 3.3 GO:0018963 phthalate metabolic process(GO:0018963)
1.6 4.8 GO:2000374 lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
1.6 4.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.6 4.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.6 6.4 GO:0048627 myoblast development(GO:0048627)
1.6 12.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.6 4.8 GO:0019482 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859)
1.6 11.1 GO:0018095 protein polyglutamylation(GO:0018095)
1.6 6.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.5 6.2 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.5 18.6 GO:0001955 blood vessel maturation(GO:0001955)
1.5 4.6 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.5 4.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.5 3.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
1.5 6.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.5 3.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
1.5 4.6 GO:0001842 neural fold formation(GO:0001842)
1.5 6.1 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
1.5 7.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
1.5 9.0 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.5 7.4 GO:0035900 response to isolation stress(GO:0035900)
1.5 4.4 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
1.5 1.5 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
1.5 4.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
1.5 5.8 GO:0048865 stem cell fate commitment(GO:0048865)
1.4 4.3 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
1.4 4.3 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
1.4 8.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.4 4.2 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.4 4.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.4 2.8 GO:0016095 polyprenol catabolic process(GO:0016095)
1.4 12.7 GO:0015693 magnesium ion transport(GO:0015693)
1.4 39.2 GO:0001502 cartilage condensation(GO:0001502)
1.4 2.8 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
1.4 2.8 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
1.4 4.1 GO:0015670 carbon dioxide transport(GO:0015670)
1.4 2.7 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.4 6.8 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
1.4 8.1 GO:1990034 calcium ion export from cell(GO:1990034)
1.4 4.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
1.3 6.7 GO:0006116 NADH oxidation(GO:0006116)
1.3 8.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.3 5.4 GO:0036018 cellular response to erythropoietin(GO:0036018)
1.3 5.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.3 9.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
1.3 6.6 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.3 5.3 GO:0071918 urea transmembrane transport(GO:0071918)
1.3 3.9 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
1.3 5.3 GO:0002357 defense response to tumor cell(GO:0002357)
1.3 18.3 GO:0006751 glutathione catabolic process(GO:0006751)
1.3 11.8 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
1.3 10.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.3 3.9 GO:0097473 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
1.3 7.8 GO:0032571 response to vitamin K(GO:0032571)
1.3 5.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
1.3 5.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.3 11.5 GO:0000101 sulfur amino acid transport(GO:0000101)
1.3 5.1 GO:0045404 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
1.3 25.3 GO:0097186 amelogenesis(GO:0097186)
1.3 3.8 GO:0036089 cleavage furrow formation(GO:0036089)
1.3 13.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.2 12.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.2 4.9 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.2 4.9 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.2 2.4 GO:0007227 signal transduction downstream of smoothened(GO:0007227)
1.2 10.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
1.2 7.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.2 24.6 GO:0032060 bleb assembly(GO:0032060)
1.2 4.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.2 4.7 GO:0035962 response to interleukin-13(GO:0035962)
1.2 5.8 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
1.2 3.5 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
1.2 3.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.2 6.9 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
1.1 12.6 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
1.1 6.9 GO:0016926 protein desumoylation(GO:0016926)
1.1 6.9 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.1 7.9 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
1.1 4.5 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
1.1 6.8 GO:0002933 lipid hydroxylation(GO:0002933)
1.1 18.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.1 2.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
1.1 8.8 GO:0007256 activation of JNKK activity(GO:0007256)
1.1 4.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.1 3.3 GO:0035624 receptor transactivation(GO:0035624)
1.1 18.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.1 3.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
1.1 5.5 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.1 2.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
1.1 8.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.1 7.5 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.1 3.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.1 6.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.1 16.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
1.1 3.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.0 8.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.0 16.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
1.0 3.1 GO:0018094 protein polyglycylation(GO:0018094)
1.0 9.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.0 3.1 GO:0000103 sulfate assimilation(GO:0000103)
1.0 6.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.0 4.0 GO:1904139 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
1.0 9.0 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
1.0 9.9 GO:0033327 Leydig cell differentiation(GO:0033327)
1.0 5.9 GO:0046092 deoxycytidine metabolic process(GO:0046092)
1.0 4.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
1.0 8.8 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.0 3.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.0 1.9 GO:1902617 response to fluoride(GO:1902617)
1.0 4.8 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.0 15.4 GO:0060973 cell migration involved in heart development(GO:0060973)
1.0 6.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.0 12.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.0 1.9 GO:0048859 formation of anatomical boundary(GO:0048859)
0.9 25.6 GO:0014850 response to muscle activity(GO:0014850)
0.9 2.8 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.9 2.8 GO:0034769 basement membrane disassembly(GO:0034769)
0.9 16.0 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.9 0.9 GO:0060157 urinary bladder development(GO:0060157)
0.9 4.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.9 2.8 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.9 12.9 GO:0010459 negative regulation of heart rate(GO:0010459)
0.9 2.7 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.9 2.7 GO:0060032 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.9 9.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.9 2.7 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.9 2.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.9 10.0 GO:0014029 neural crest formation(GO:0014029)
0.9 4.5 GO:0001555 oocyte growth(GO:0001555)
0.9 3.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.9 45.0 GO:0050919 negative chemotaxis(GO:0050919)
0.9 22.9 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.9 6.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.9 2.6 GO:0016103 isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.9 4.3 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.9 7.8 GO:0042428 serotonin metabolic process(GO:0042428)
0.9 2.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.9 11.3 GO:0045008 depyrimidination(GO:0045008)
0.9 1.7 GO:0010159 specification of organ position(GO:0010159)
0.9 12.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.9 4.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.9 2.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.9 6.0 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.9 6.8 GO:0060174 limb bud formation(GO:0060174)
0.9 5.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.8 11.0 GO:0042448 progesterone metabolic process(GO:0042448)
0.8 1.7 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.8 24.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.8 3.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.8 6.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.8 2.5 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.8 14.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.8 5.8 GO:0043307 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.8 20.6 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.8 22.1 GO:0006706 steroid catabolic process(GO:0006706)
0.8 56.6 GO:0006953 acute-phase response(GO:0006953)
0.8 11.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.8 15.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 2.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.8 3.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.8 4.0 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.8 6.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.8 3.2 GO:0007386 compartment pattern specification(GO:0007386)
0.8 6.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.8 10.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.8 7.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.8 3.9 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.8 3.9 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.8 2.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.8 5.5 GO:0043129 surfactant homeostasis(GO:0043129)
0.8 7.8 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.8 8.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.8 3.1 GO:1990834 response to odorant(GO:1990834)
0.8 8.5 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.8 1.5 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.8 6.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.8 3.8 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.8 3.0 GO:0019740 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740)
0.7 14.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.7 4.5 GO:0035063 nuclear speck organization(GO:0035063)
0.7 3.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.7 18.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.7 1.5 GO:0050955 thermoception(GO:0050955)
0.7 2.2 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.7 82.3 GO:0030449 regulation of complement activation(GO:0030449)
0.7 2.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.7 7.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 6.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.7 9.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.7 6.3 GO:0015886 heme transport(GO:0015886)
0.7 4.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.7 2.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.7 8.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.7 2.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.7 2.7 GO:0048318 axial mesoderm development(GO:0048318)
0.7 2.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.7 3.4 GO:0002024 diet induced thermogenesis(GO:0002024)
0.7 2.0 GO:0044804 nucleophagy(GO:0044804)
0.7 2.7 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.7 4.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.7 1.3 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.7 4.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.7 6.0 GO:0043589 skin morphogenesis(GO:0043589)
0.7 2.6 GO:0006550 isoleucine catabolic process(GO:0006550)
0.7 29.6 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.7 2.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.7 12.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.7 1.3 GO:0048242 regulation of epinephrine secretion(GO:0014060) epinephrine secretion(GO:0048242)
0.6 5.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.6 1.9 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.6 4.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.6 9.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.6 1.3 GO:0072070 cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309) loop of Henle development(GO:0072070)
0.6 5.8 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.6 1.9 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.6 14.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.6 1.9 GO:1902943 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.6 1.9 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.6 5.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.6 6.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.6 15.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.6 4.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.6 3.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.6 6.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.6 3.0 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.6 12.7 GO:0014002 astrocyte development(GO:0014002)
0.6 1.8 GO:1902473 regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.6 3.0 GO:1904936 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.6 1.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.6 3.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.6 3.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.6 6.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6 4.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.6 4.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.6 5.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.6 25.9 GO:0015701 bicarbonate transport(GO:0015701)
0.6 22.3 GO:0071625 vocalization behavior(GO:0071625)
0.6 7.8 GO:1990123 L-glutamate import across plasma membrane(GO:0098712) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.6 1.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.6 7.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.6 9.4 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.6 2.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.6 11.0 GO:0006833 water transport(GO:0006833)
0.5 3.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 8.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.5 6.5 GO:0046415 urate metabolic process(GO:0046415)
0.5 4.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 6.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 3.8 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.5 11.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.5 7.9 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.5 3.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.5 8.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.5 10.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 1.5 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.5 1.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.5 4.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 4.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.5 0.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.5 2.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.5 3.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.5 5.3 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.5 2.9 GO:0070633 transepithelial transport(GO:0070633)
0.5 2.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.5 2.4 GO:0007220 Notch receptor processing(GO:0007220)
0.5 3.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.5 1.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 7.6 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.5 0.9 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.5 3.8 GO:0099612 protein localization to axon(GO:0099612)
0.5 2.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.5 2.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.5 3.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.5 1.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 3.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.5 2.7 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.5 7.2 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.5 2.7 GO:0006021 inositol biosynthetic process(GO:0006021)
0.4 6.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 6.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 4.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.4 3.0 GO:0070995 NADPH oxidation(GO:0070995)
0.4 8.3 GO:0070741 response to interleukin-6(GO:0070741)
0.4 1.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.4 1.7 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.4 1.7 GO:0030903 notochord development(GO:0030903)
0.4 1.3 GO:0090009 primitive streak formation(GO:0090009)
0.4 4.7 GO:0003094 glomerular filtration(GO:0003094)
0.4 17.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 3.4 GO:0051601 exocyst localization(GO:0051601)
0.4 9.7 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.4 5.0 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.4 14.9 GO:0007140 male meiosis(GO:0007140)
0.4 1.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.4 2.0 GO:0034091 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.4 4.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.4 3.3 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4 2.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.4 1.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.4 2.0 GO:0060033 anatomical structure regression(GO:0060033)
0.4 6.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.4 3.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.4 3.5 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.4 4.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.4 3.9 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.4 2.3 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 16.7 GO:0018149 peptide cross-linking(GO:0018149)
0.4 10.2 GO:0000732 strand displacement(GO:0000732)
0.4 3.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 22.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.4 11.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.4 12.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 1.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.4 3.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 7.3 GO:0001755 neural crest cell migration(GO:0001755)
0.4 2.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 5.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.4 3.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 7.1 GO:0035272 exocrine system development(GO:0035272)
0.4 4.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.4 23.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.4 4.6 GO:0003197 endocardial cushion development(GO:0003197)
0.4 7.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.4 4.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 0.4 GO:0021603 cranial nerve formation(GO:0021603)
0.4 1.1 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.3 2.1 GO:0030238 male sex determination(GO:0030238)
0.3 4.5 GO:0019388 galactose catabolic process(GO:0019388)
0.3 2.8 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.0 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 1.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.0 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.3 5.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 1.7 GO:0048484 enteric nervous system development(GO:0048484)
0.3 5.8 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 7.8 GO:0042572 retinol metabolic process(GO:0042572)
0.3 4.4 GO:0071318 cellular response to ATP(GO:0071318)
0.3 3.0 GO:0048266 behavioral response to pain(GO:0048266)
0.3 9.4 GO:0014047 glutamate secretion(GO:0014047)
0.3 22.5 GO:0030574 collagen catabolic process(GO:0030574)
0.3 1.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 2.0 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.3 4.7 GO:0032098 regulation of appetite(GO:0032098)
0.3 5.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 2.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.3 4.6 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.3 2.9 GO:0060019 radial glial cell differentiation(GO:0060019)
0.3 5.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 4.9 GO:0031643 positive regulation of myelination(GO:0031643)
0.3 1.9 GO:0051546 keratinocyte migration(GO:0051546)
0.3 1.9 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.3 6.1 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.3 7.0 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.3 6.3 GO:1902001 carnitine shuttle(GO:0006853) fatty acid transmembrane transport(GO:1902001)
0.3 4.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 2.8 GO:0010265 SCF complex assembly(GO:0010265)
0.3 4.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 1.5 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.3 2.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.3 4.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.2 GO:0070307 lens fiber cell development(GO:0070307)
0.3 3.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 8.9 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.3 2.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 22.3 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.3 7.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 2.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.3 2.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.3 2.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.3 8.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.3 1.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 1.1 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.3 4.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3 3.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.3 18.1 GO:0009583 detection of light stimulus(GO:0009583)
0.3 3.3 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.3 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.3 1.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 3.7 GO:0035855 megakaryocyte development(GO:0035855)
0.3 1.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 0.8 GO:0048539 bone marrow development(GO:0048539)
0.3 21.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.3 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 2.8 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.2 3.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 9.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 1.2 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.2 1.7 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.7 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 0.5 GO:0015824 proline transport(GO:0015824)
0.2 2.1 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.2 2.6 GO:0035640 exploration behavior(GO:0035640)
0.2 2.6 GO:0035330 regulation of hippo signaling(GO:0035330)
0.2 1.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 9.5 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.2 1.2 GO:0072386 plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 1.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 13.3 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.2 0.9 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.2 2.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 3.1 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.2 3.6 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.6 GO:0030252 growth hormone secretion(GO:0030252)
0.2 2.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 2.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 2.4 GO:0030199 collagen fibril organization(GO:0030199)
0.2 6.8 GO:0003407 neural retina development(GO:0003407)
0.2 1.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 8.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.2 11.8 GO:0030901 midbrain development(GO:0030901)
0.2 32.3 GO:0030073 insulin secretion(GO:0030073)
0.2 1.0 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 1.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 21.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 3.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.2 14.9 GO:0008366 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.2 0.8 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 5.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 1.6 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 1.1 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
0.2 3.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 1.9 GO:0015801 aromatic amino acid transport(GO:0015801)
0.2 2.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 2.6 GO:0006828 manganese ion transport(GO:0006828)
0.2 7.0 GO:0008585 female gonad development(GO:0008585)
0.2 6.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.2 2.9 GO:0044458 motile cilium assembly(GO:0044458)
0.2 1.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 2.9 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.2 3.4 GO:0016486 peptide hormone processing(GO:0016486)
0.2 0.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.2 2.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.1 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.2 15.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.2 0.6 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2 6.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 1.2 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 5.2 GO:0010107 potassium ion import(GO:0010107)
0.1 5.0 GO:0001706 endoderm formation(GO:0001706)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.4 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 2.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 3.9 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 5.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.6 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 3.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 2.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.9 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.2 GO:0046514 ceramide catabolic process(GO:0046514)
0.1 0.4 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.1 1.8 GO:0006582 melanin metabolic process(GO:0006582)
0.1 0.6 GO:0006449 regulation of translational termination(GO:0006449)
0.1 7.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 14.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 9.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.9 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 1.6 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.5 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 2.2 GO:0031670 cellular response to nutrient(GO:0031670)
0.1 0.4 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 2.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.4 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 2.6 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 0.7 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 2.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 8.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 3.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 4.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 4.0 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.1 0.8 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0070254 mucus secretion(GO:0070254)
0.1 2.9 GO:0006970 response to osmotic stress(GO:0006970)
0.1 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.8 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 1.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 1.5 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 2.1 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 0.9 GO:0003170 heart valve development(GO:0003170)
0.1 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 1.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.0 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.3 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.7 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 2.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.8 GO:0006968 cellular defense response(GO:0006968)
0.0 1.5 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.5 GO:0061053 somite development(GO:0061053)
0.0 0.1 GO:0014010 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0 0.5 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.0 GO:0002583 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) regulation of antigen processing and presentation of peptide antigen(GO:0002583) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)
0.0 0.0 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.9 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.3 GO:0036028 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
5.3 21.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.5 13.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
3.7 22.4 GO:0045298 tubulin complex(GO:0045298)
3.0 6.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
3.0 17.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
2.8 8.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
2.7 8.0 GO:0072563 endothelial microparticle(GO:0072563)
2.1 8.6 GO:0097440 apical dendrite(GO:0097440)
2.1 6.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
2.1 6.4 GO:0070382 exocytic vesicle(GO:0070382)
2.1 12.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
2.1 6.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
2.0 6.0 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.9 13.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.9 15.3 GO:0032133 chromosome passenger complex(GO:0032133)
1.9 34.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.9 9.4 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.8 5.4 GO:0036398 TCR signalosome(GO:0036398)
1.7 31.4 GO:0005922 connexon complex(GO:0005922)
1.7 18.9 GO:0043203 axon hillock(GO:0043203)
1.7 8.5 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
1.6 14.3 GO:0000813 ESCRT I complex(GO:0000813)
1.6 14.2 GO:0044294 dendritic growth cone(GO:0044294)
1.6 18.9 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.6 6.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
1.5 13.9 GO:0098845 postsynaptic endosome(GO:0098845)
1.5 16.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.5 4.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
1.4 7.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.4 5.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.4 15.6 GO:0098651 basement membrane collagen trimer(GO:0098651)
1.4 7.1 GO:0097513 myosin II filament(GO:0097513)
1.4 4.2 GO:0071546 pi-body(GO:0071546)
1.3 20.2 GO:0097433 dense body(GO:0097433)
1.3 4.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.3 10.2 GO:0005579 membrane attack complex(GO:0005579)
1.2 7.3 GO:0005594 collagen type IX trimer(GO:0005594)
1.2 4.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.2 38.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.2 15.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.2 10.5 GO:0042788 polysomal ribosome(GO:0042788)
1.2 4.6 GO:0005826 actomyosin contractile ring(GO:0005826)
1.1 18.3 GO:0097512 cardiac myofibril(GO:0097512)
1.1 28.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.1 5.5 GO:0032444 activin responsive factor complex(GO:0032444)
1.1 5.5 GO:0089701 U2AF(GO:0089701)
1.1 8.6 GO:0000138 Golgi trans cisterna(GO:0000138)
1.1 15.8 GO:0030478 actin cap(GO:0030478)
1.0 5.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.0 6.0 GO:0032584 growth cone membrane(GO:0032584)
1.0 5.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.0 7.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.0 13.5 GO:0031906 late endosome lumen(GO:0031906)
1.0 10.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.9 2.8 GO:0031933 telomeric heterochromatin(GO:0031933)
0.9 6.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.9 4.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.9 9.1 GO:0097443 sorting endosome(GO:0097443)
0.9 17.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.9 6.3 GO:0036021 endolysosome lumen(GO:0036021)
0.9 13.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.9 5.3 GO:0033391 chromatoid body(GO:0033391)
0.9 4.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.8 90.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.8 21.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.8 8.4 GO:0035253 ciliary rootlet(GO:0035253)
0.8 4.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.8 5.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.8 2.4 GO:0005899 insulin receptor complex(GO:0005899)
0.8 13.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8 4.8 GO:0005927 muscle tendon junction(GO:0005927)
0.8 2.4 GO:0035517 PR-DUB complex(GO:0035517)
0.8 3.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 8.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.7 17.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.7 1.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.7 6.7 GO:0061574 ASAP complex(GO:0061574)
0.7 2.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.7 3.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.6 3.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 8.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.6 28.2 GO:0001533 cornified envelope(GO:0001533)
0.6 3.8 GO:1990769 proximal neuron projection(GO:1990769)
0.6 7.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 6.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.6 11.0 GO:0097225 sperm midpiece(GO:0097225)
0.6 3.0 GO:1990031 pinceau fiber(GO:1990031)
0.6 4.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.6 3.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.6 3.6 GO:0002177 manchette(GO:0002177)
0.6 3.0 GO:0045179 apical cortex(GO:0045179)
0.6 10.7 GO:0071141 SMAD protein complex(GO:0071141)
0.6 1.2 GO:0043259 laminin-10 complex(GO:0043259)
0.6 4.6 GO:0005845 mRNA cap binding complex(GO:0005845)
0.6 3.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.6 12.1 GO:0030056 hemidesmosome(GO:0030056)
0.5 17.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.5 14.0 GO:0043218 compact myelin(GO:0043218)
0.5 18.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 3.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5 1.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.5 87.0 GO:0072562 blood microparticle(GO:0072562)
0.5 11.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 3.9 GO:0000322 storage vacuole(GO:0000322)
0.5 3.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 7.9 GO:1990909 Wnt signalosome(GO:1990909)
0.5 7.9 GO:0005861 troponin complex(GO:0005861)
0.4 27.9 GO:0005796 Golgi lumen(GO:0005796)
0.4 31.3 GO:0034707 chloride channel complex(GO:0034707)
0.4 4.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 5.5 GO:0043083 synaptic cleft(GO:0043083)
0.4 8.3 GO:0031904 endosome lumen(GO:0031904)
0.4 2.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 3.3 GO:0070852 cell body fiber(GO:0070852)
0.4 4.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 2.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 5.2 GO:0046930 pore complex(GO:0046930)
0.4 11.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 3.1 GO:0005916 fascia adherens(GO:0005916)
0.4 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 11.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.4 2.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 13.6 GO:0009925 basal plasma membrane(GO:0009925)
0.4 4.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 9.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.4 2.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 15.5 GO:0000795 synaptonemal complex(GO:0000795)
0.3 9.3 GO:0032590 dendrite membrane(GO:0032590)
0.3 14.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 7.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 3.0 GO:0002080 acrosomal membrane(GO:0002080)
0.3 3.3 GO:0005915 zonula adherens(GO:0005915)
0.3 5.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 44.9 GO:0031225 anchored component of membrane(GO:0031225)
0.3 32.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 2.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 17.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 110.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 3.4 GO:0000145 exocyst(GO:0000145)
0.3 79.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 22.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 2.3 GO:0072487 MSL complex(GO:0072487)
0.3 1.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 2.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 9.8 GO:0034451 centriolar satellite(GO:0034451)
0.3 3.2 GO:0017119 Golgi transport complex(GO:0017119)
0.3 4.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 2.0 GO:0061689 tricellular tight junction(GO:0061689)
0.3 4.5 GO:0036038 MKS complex(GO:0036038)
0.3 22.7 GO:0042734 presynaptic membrane(GO:0042734)
0.3 11.5 GO:0097546 ciliary base(GO:0097546)
0.3 310.3 GO:0005615 extracellular space(GO:0005615)
0.3 4.8 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.3 9.8 GO:0005902 microvillus(GO:0005902)
0.3 26.3 GO:0043204 perikaryon(GO:0043204)
0.3 1.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 1.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 1.2 GO:0032010 secondary lysosome(GO:0005767) phagolysosome(GO:0032010)
0.2 4.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 3.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 29.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 4.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 2.7 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 2.7 GO:0016013 syntrophin complex(GO:0016013)
0.2 2.6 GO:0030673 axolemma(GO:0030673)
0.2 3.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.1 GO:0019814 immunoglobulin complex(GO:0019814)
0.2 15.0 GO:0005776 autophagosome(GO:0005776)
0.2 8.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 6.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 1.2 GO:0031045 dense core granule(GO:0031045)
0.2 5.3 GO:0005901 caveola(GO:0005901)
0.2 12.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 37.4 GO:0098793 presynapse(GO:0098793)
0.2 2.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 4.5 GO:0071565 nBAF complex(GO:0071565)
0.2 1.3 GO:0005833 hemoglobin complex(GO:0005833)
0.2 8.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 6.8 GO:0035579 specific granule membrane(GO:0035579)
0.1 2.9 GO:0014704 intercalated disc(GO:0014704)
0.1 9.8 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.8 GO:0031082 BLOC complex(GO:0031082)
0.1 16.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 180.2 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.1 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.1 GO:0044613 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.1 2.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 3.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 7.6 GO:0005811 lipid particle(GO:0005811)
0.1 5.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.8 GO:0097542 ciliary tip(GO:0097542)
0.1 1.5 GO:0043679 axon terminus(GO:0043679)
0.1 2.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 6.5 GO:0001726 ruffle(GO:0001726)
0.1 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 2.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 5.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 4.4 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.8 GO:0016605 PML body(GO:0016605)
0.0 4.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 29.5 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.2 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 41.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
6.3 19.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
6.3 19.0 GO:0016497 substance K receptor activity(GO:0016497)
5.7 22.8 GO:0004773 steryl-sulfatase activity(GO:0004773)
5.6 22.4 GO:0099609 microtubule lateral binding(GO:0099609)
5.4 16.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
5.0 15.0 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
4.6 4.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
3.9 11.7 GO:0004336 galactosylceramidase activity(GO:0004336)
3.9 15.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
3.7 21.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
3.6 21.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
3.4 10.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
3.3 9.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
3.2 32.0 GO:0008131 primary amine oxidase activity(GO:0008131)
3.2 22.3 GO:0030492 hemoglobin binding(GO:0030492)
3.2 9.5 GO:0008431 vitamin E binding(GO:0008431)
3.1 27.6 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
3.0 6.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
2.9 23.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
2.9 14.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.9 5.8 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
2.8 11.2 GO:0061714 folic acid receptor activity(GO:0061714)
2.7 51.6 GO:0038191 neuropilin binding(GO:0038191)
2.7 16.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
2.6 13.0 GO:0004522 ribonuclease A activity(GO:0004522)
2.6 12.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.5 12.7 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
2.5 10.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
2.5 7.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
2.5 14.9 GO:0004359 glutaminase activity(GO:0004359)
2.5 9.9 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
2.4 19.4 GO:0004111 creatine kinase activity(GO:0004111)
2.4 7.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.4 14.3 GO:0008420 CTD phosphatase activity(GO:0008420)
2.4 11.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
2.3 11.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
2.3 6.8 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
2.2 13.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.2 6.7 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
2.2 11.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
2.2 8.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
2.2 11.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
2.2 28.3 GO:0036122 BMP binding(GO:0036122)
2.2 8.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
2.1 8.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
2.1 6.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
2.1 31.4 GO:0005243 gap junction channel activity(GO:0005243)
2.1 6.3 GO:0004967 glucagon receptor activity(GO:0004967)
2.1 8.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
2.0 6.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.9 11.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.9 17.3 GO:0032190 acrosin binding(GO:0032190)
1.9 5.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.8 7.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.8 14.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 9.1 GO:0004994 somatostatin receptor activity(GO:0004994)
1.8 12.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.8 5.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.8 5.3 GO:0032093 SAM domain binding(GO:0032093)
1.8 5.3 GO:0015265 urea channel activity(GO:0015265)
1.7 15.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.7 8.6 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.7 8.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.6 45.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.6 9.6 GO:0030172 troponin C binding(GO:0030172)
1.6 12.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.6 6.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.6 20.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.6 4.7 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.5 9.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.5 7.5 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.5 19.3 GO:0070700 BMP receptor binding(GO:0070700)
1.5 7.4 GO:0008422 beta-glucosidase activity(GO:0008422)
1.5 4.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.5 13.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
1.5 16.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
1.5 4.4 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
1.5 7.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
1.5 31.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.4 5.7 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.4 4.2 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.4 4.2 GO:0009378 four-way junction helicase activity(GO:0009378)
1.4 4.2 GO:0031696 alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
1.4 4.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
1.4 18.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.4 5.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.3 4.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
1.3 28.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.3 10.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
1.3 19.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.3 7.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
1.3 5.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.3 11.4 GO:0050682 AF-2 domain binding(GO:0050682)
1.3 7.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.3 6.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.2 3.7 GO:0070538 oleic acid binding(GO:0070538)
1.2 4.9 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
1.2 4.9 GO:0004461 lactose synthase activity(GO:0004461)
1.2 7.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
1.2 12.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.2 19.1 GO:0050693 LBD domain binding(GO:0050693)
1.2 17.8 GO:0005372 water transmembrane transporter activity(GO:0005372)
1.2 4.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.2 2.3 GO:0070905 serine binding(GO:0070905)
1.2 5.8 GO:0042610 CD8 receptor binding(GO:0042610)
1.2 16.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.1 11.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
1.1 6.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.1 5.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.1 15.8 GO:0045159 myosin II binding(GO:0045159)
1.1 5.6 GO:0001594 trace-amine receptor activity(GO:0001594)
1.1 3.4 GO:0005055 laminin receptor activity(GO:0005055)
1.1 1.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
1.1 3.3 GO:0052835 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
1.1 3.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.1 8.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.1 6.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.1 14.0 GO:1990239 steroid hormone binding(GO:1990239)
1.1 6.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
1.1 4.2 GO:0071253 connexin binding(GO:0071253)
1.1 9.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.0 6.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.0 8.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.0 11.4 GO:0032051 clathrin light chain binding(GO:0032051)
1.0 4.1 GO:0002046 opsin binding(GO:0002046)
1.0 3.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
1.0 4.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
1.0 5.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.0 3.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
1.0 102.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.0 27.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.0 3.9 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.0 5.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.0 15.7 GO:0019841 retinol binding(GO:0019841)
1.0 4.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.0 2.9 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
1.0 2.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.0 11.6 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
1.0 2.9 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.9 8.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.9 42.5 GO:0008009 chemokine activity(GO:0008009)
0.9 1.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.9 2.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.9 9.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.9 7.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 2.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.9 7.2 GO:0043426 MRF binding(GO:0043426)
0.9 7.2 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.9 9.7 GO:0036310 annealing helicase activity(GO:0036310)
0.9 2.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.9 6.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 3.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 2.6 GO:0042806 fucose binding(GO:0042806)
0.9 7.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.8 5.9 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.8 11.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.8 10.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.8 3.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.8 6.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.8 4.9 GO:0098821 BMP receptor activity(GO:0098821)
0.8 10.7 GO:0046870 cadmium ion binding(GO:0046870)
0.8 18.0 GO:0016805 dipeptidase activity(GO:0016805)
0.8 43.2 GO:0005158 insulin receptor binding(GO:0005158)
0.8 14.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.8 2.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.8 4.0 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.8 4.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.8 3.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8 2.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.8 5.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.8 6.3 GO:0015232 heme transporter activity(GO:0015232)
0.8 3.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.8 9.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.8 16.1 GO:0051787 misfolded protein binding(GO:0051787)
0.8 65.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.8 5.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.8 3.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.7 12.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.7 4.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.7 7.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.7 6.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.7 3.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.7 2.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.7 8.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.7 3.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.7 9.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.7 6.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.7 9.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.7 197.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.7 2.8 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.7 9.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.7 2.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 12.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.7 6.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.7 10.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.7 1.3 GO:0033265 choline binding(GO:0033265)
0.7 4.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.7 2.7 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.7 4.7 GO:0005497 androgen binding(GO:0005497)
0.7 40.4 GO:0070412 R-SMAD binding(GO:0070412)
0.7 2.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.7 7.2 GO:0019864 IgG binding(GO:0019864)
0.7 2.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.7 2.0 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.7 3.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.7 3.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.7 6.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.6 2.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 2.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.6 20.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.6 2.6 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.6 6.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.6 1.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.6 2.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.6 1.9 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.6 1.9 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.6 5.0 GO:0042608 T cell receptor binding(GO:0042608)
0.6 12.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.6 1.8 GO:0016803 ether hydrolase activity(GO:0016803) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.6 37.2 GO:0030507 spectrin binding(GO:0030507)
0.6 2.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.6 3.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.6 4.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.6 9.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6 2.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.6 7.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.6 7.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 3.3 GO:0043237 laminin-1 binding(GO:0043237)
0.5 1.6 GO:0004630 phospholipase D activity(GO:0004630)
0.5 7.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 2.2 GO:0035473 lipase binding(GO:0035473)
0.5 4.8 GO:0050780 dopamine receptor binding(GO:0050780)
0.5 2.1 GO:0035939 microsatellite binding(GO:0035939)
0.5 2.6 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 4.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 7.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.5 17.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 13.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 2.6 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 21.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.5 3.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 2.0 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.5 11.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.5 1.5 GO:0070984 SET domain binding(GO:0070984)
0.5 3.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 9.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.5 5.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 8.6 GO:0000146 microfilament motor activity(GO:0000146)
0.5 26.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 5.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 11.0 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.5 12.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5 1.9 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.5 11.8 GO:0030169 hyaluronic acid binding(GO:0005540) low-density lipoprotein particle binding(GO:0030169)
0.5 12.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.5 3.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 3.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5 11.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 11.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 1.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 15.8 GO:0071837 HMG box domain binding(GO:0071837)
0.4 2.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.4 8.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 5.2 GO:0051434 BH3 domain binding(GO:0051434)
0.4 4.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 4.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 3.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.4 1.7 GO:0043273 CTPase activity(GO:0043273)
0.4 5.4 GO:0046790 virion binding(GO:0046790)
0.4 3.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 2.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 2.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 5.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 4.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.4 3.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.4 2.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.4 7.6 GO:0031005 filamin binding(GO:0031005)
0.4 12.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 5.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 5.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 1.5 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.4 3.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.4 15.7 GO:0008236 serine-type peptidase activity(GO:0008236)
0.4 3.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.4 0.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.4 1.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.4 1.5 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.4 4.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 7.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.4 20.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 3.6 GO:0005549 odorant binding(GO:0005549)
0.3 1.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 4.5 GO:0048018 receptor agonist activity(GO:0048018)
0.3 1.0 GO:0036505 prosaposin receptor activity(GO:0036505)
0.3 2.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 4.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 15.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 12.9 GO:0008374 O-acyltransferase activity(GO:0008374)
0.3 6.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 2.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 4.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 18.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 4.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 3.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 4.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 4.3 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 17.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 33.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 2.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.3 2.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 1.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.3 2.6 GO:0070679 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 7.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 0.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 2.8 GO:0051184 cofactor transporter activity(GO:0051184)
0.3 8.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 9.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.3 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 3.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 9.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 8.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.3 0.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.3 20.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 5.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 2.4 GO:0004969 histamine receptor activity(GO:0004969)
0.3 6.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 2.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 1.8 GO:0001515 opioid peptide activity(GO:0001515)
0.3 14.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3 4.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 0.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 4.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 1.5 GO:0032027 myosin light chain binding(GO:0032027)
0.2 2.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.7 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.2 6.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 5.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 0.7 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 25.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 5.3 GO:0019840 isoprenoid binding(GO:0019840)
0.2 3.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.4 GO:0017040 ceramidase activity(GO:0017040)
0.2 21.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 3.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 9.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 6.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 13.4 GO:0030165 PDZ domain binding(GO:0030165)
0.2 4.1 GO:0008066 glutamate receptor activity(GO:0008066)
0.2 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.2 1.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2 6.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 3.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.7 GO:0030552 cAMP binding(GO:0030552)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 3.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.5 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2 1.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 3.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 6.3 GO:0019838 growth factor binding(GO:0019838)
0.2 24.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.6 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.2 1.0 GO:0004046 aminoacylase activity(GO:0004046)
0.2 1.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 18.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 5.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 4.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 6.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 3.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 10.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.8 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 7.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.1 GO:0010851 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 0.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 10.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 3.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0015389 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 6.6 GO:0005262 calcium channel activity(GO:0005262)
0.1 10.3 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 4.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 8.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 27.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 4.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.1 GO:0005261 cation channel activity(GO:0005261)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 76.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.0 14.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.9 16.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.9 17.1 PID ALK2 PATHWAY ALK2 signaling events
0.8 33.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.8 13.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.8 18.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.8 4.9 PID ALK1 PATHWAY ALK1 signaling events
0.8 58.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.7 33.4 NABA COLLAGENS Genes encoding collagen proteins
0.7 21.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.7 24.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7 4.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.6 3.1 PID REELIN PATHWAY Reelin signaling pathway
0.6 4.4 PID IL27 PATHWAY IL27-mediated signaling events
0.6 9.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.6 44.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.6 3.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.6 100.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.6 10.6 PID AURORA A PATHWAY Aurora A signaling
0.6 9.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.5 197.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.5 17.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.5 15.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.5 6.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.5 8.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 13.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 6.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.4 23.3 PID ARF6 PATHWAY Arf6 signaling events
0.4 27.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 2.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.4 13.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.4 103.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 13.6 PID RAS PATHWAY Regulation of Ras family activation
0.3 2.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 9.3 PID SHP2 PATHWAY SHP2 signaling
0.3 11.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 2.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 2.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 2.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 7.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 14.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 4.6 PID BCR 5PATHWAY BCR signaling pathway
0.3 1.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 59.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 1.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 11.3 PID LKB1 PATHWAY LKB1 signaling events
0.2 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.2 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 10.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 4.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 11.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 5.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 7.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 6.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 2.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 12.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 5.8 PID FGF PATHWAY FGF signaling pathway
0.2 5.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 7.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 7.1 PID NOTCH PATHWAY Notch signaling pathway
0.2 3.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 4.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 2.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 3.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 5.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 5.6 PID ATM PATHWAY ATM pathway
0.1 3.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.4 PID BARD1 PATHWAY BARD1 signaling events
0.1 3.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.6 ST GA13 PATHWAY G alpha 13 Pathway
0.1 3.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.9 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 4.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 8.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.1 27.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.7 31.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
1.6 39.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.6 31.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
1.4 2.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.4 17.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.3 22.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.2 17.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.2 38.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
1.2 17.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.2 18.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.1 24.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.0 30.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.0 4.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.0 32.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.9 9.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.9 6.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.9 14.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.9 18.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.9 23.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9 20.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.8 16.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.8 2.5 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.8 8.1 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.8 15.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.8 16.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.8 2.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.7 8.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7 6.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.7 23.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.7 40.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.7 27.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.6 12.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 40.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.6 7.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 9.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 124.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.6 10.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.6 8.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.6 1.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 30.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.5 8.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 11.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 20.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 4.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.5 2.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5 6.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 9.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.4 10.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 16.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4 45.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.4 3.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.4 13.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 15.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 13.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 4.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 9.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 4.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 7.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.4 17.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.4 2.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.4 16.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.4 1.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.4 7.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 6.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 11.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 4.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 17.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 10.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.3 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 6.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.3 4.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 4.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 5.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 4.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 23.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 9.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 18.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 29.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 2.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 0.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 3.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 4.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 7.5 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.2 11.1 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.2 6.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 4.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 4.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 4.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 3.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 2.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 5.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 20.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 3.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 4.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.2 3.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 3.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 3.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 5.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 6.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 2.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 16.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 9.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.0 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 4.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 3.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation