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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HINFP

Z-value: 1.67

Motif logo

Transcription factors associated with HINFP

Gene Symbol Gene ID Gene Info
ENSG00000172273.13 HINFP

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HINFPhg38_v1_chr11_+_119121559_1191216240.073.2e-01Click!

Activity profile of HINFP motif

Sorted Z-values of HINFP motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_94394886 10.15 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr11_-_125592448 6.23 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr6_-_106975616 5.90 ENST00000610952.1
CD24 molecule
chr6_-_106975452 5.84 ENST00000619869.1
ENST00000619133.4
CD24 molecule
chr8_-_27605271 5.67 ENST00000522098.1
clusterin
chr5_+_176238365 5.42 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SUMO interacting motifs containing 1
chr6_-_106975309 4.81 ENST00000615659.1
CD24 molecule
chr4_-_499102 4.29 ENST00000338977.5
ENST00000511833.3
zinc finger protein 721
chr16_-_23557331 3.96 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr9_+_128203397 3.50 ENST00000628346.2
ENST00000486160.3
ENST00000627061.2
ENST00000627543.2
ENST00000634267.2
dynamin 1
chr9_+_128203371 3.39 ENST00000475805.5
ENST00000372923.8
ENST00000341179.11
ENST00000393594.7
dynamin 1
chr13_-_76886397 3.19 ENST00000377474.4
potassium channel tetramerization domain containing 12
chr20_-_36863517 3.14 ENST00000237536.9
suppressor of glucose, autophagy associated 1
chr14_+_75428011 2.97 ENST00000651602.1
ENST00000559060.5
Jun dimerization protein 2
chr22_-_27801712 2.91 ENST00000302326.5
MN1 proto-oncogene, transcriptional regulator
chr9_-_137028271 2.83 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr15_+_43510945 2.67 ENST00000382031.5
microtubule associated protein 1A
chr22_+_18110679 2.63 ENST00000316027.10
tubulin alpha 8
chrX_-_34657274 2.59 ENST00000275954.4
transmembrane protein 47
chr9_-_98255589 2.53 ENST00000342112.9
TBC1 domain family member 2
chr6_-_139374605 2.49 ENST00000618718.1
ENST00000367651.4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
chr8_-_65842051 2.49 ENST00000401827.8
phosphodiesterase 7A
chr1_-_92486916 2.43 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr9_+_37650947 2.40 ENST00000377765.8
FERM and PDZ domain containing 1
chr8_+_32548267 2.35 ENST00000356819.7
neuregulin 1
chr19_+_45251363 2.30 ENST00000620044.4
microtubule affinity regulating kinase 4
chr7_-_140924699 2.28 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chrX_+_44873552 2.28 ENST00000683021.1
lysine demethylase 6A
chr11_-_132943671 2.28 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr8_+_32548303 2.26 ENST00000650967.1
neuregulin 1
chr16_+_6019585 2.25 ENST00000547372.5
RNA binding fox-1 homolog 1
chr19_-_13906062 2.21 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr6_+_43576119 2.20 ENST00000372236.9
DNA polymerase eta
chr3_-_129893551 2.18 ENST00000505616.5
ENST00000426664.6
ENST00000648771.1
ENST00000393238.8
transmembrane and coiled-coil domain family 1
chr2_-_98936155 2.17 ENST00000428096.5
ENST00000397899.7
ENST00000420294.1
CRACD like
chr12_+_53380141 2.15 ENST00000551969.5
ENST00000327443.9
Sp1 transcription factor
chr15_+_91100194 2.10 ENST00000394232.6
synaptic vesicle glycoprotein 2B
chr6_-_88963409 2.07 ENST00000369475.7
ENST00000538899.2
RNA guanylyltransferase and 5'-phosphatase
chr8_+_32548210 2.07 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr19_+_34481736 2.06 ENST00000590071.7
WT1 interacting protein
chr20_-_33443651 2.06 ENST00000217381.3
syntrophin alpha 1
chr19_+_7680822 2.06 ENST00000596148.3
ENST00000317378.5
ENST00000426877.2
trafficking protein particle complex 5
chrX_+_21374608 2.05 ENST00000644295.1
ENST00000645074.1
ENST00000645791.1
ENST00000643220.1
connector enhancer of kinase suppressor of Ras 2
chr9_-_98255618 2.05 ENST00000375066.6
ENST00000465784.7
TBC1 domain family member 2
chr11_-_32435557 2.00 ENST00000332351.9
WT1 transcription factor
chr12_+_133037533 1.99 ENST00000327668.11
zinc finger protein 84
chr12_+_133037476 1.99 ENST00000540031.5
ENST00000539354.6
ENST00000536123.5
zinc finger protein 84
chr13_-_36131352 1.96 ENST00000360631.8
doublecortin like kinase 1
chr17_+_76384601 1.95 ENST00000592299.6
ENST00000590959.5
ENST00000323374.8
sphingosine kinase 1
chr6_+_43576205 1.90 ENST00000372226.1
ENST00000443535.1
DNA polymerase eta
chr18_-_268019 1.89 ENST00000631280.2
ENST00000616322.4
ENST00000261600.11
THO complex 1
chr8_+_32548661 1.89 ENST00000650980.1
ENST00000405005.7
neuregulin 1
chr9_-_137028223 1.88 ENST00000341511.11
ATP binding cassette subfamily A member 2
chr6_-_35497042 1.87 ENST00000639578.3
ENST00000338863.13
TEA domain transcription factor 3
chr11_+_1390273 1.86 ENST00000526678.5
BR serine/threonine kinase 2
chr19_+_45251249 1.84 ENST00000262891.9
ENST00000300843.8
microtubule affinity regulating kinase 4
chr2_-_60553409 1.83 ENST00000358510.6
ENST00000643004.1
BAF chromatin remodeling complex subunit BCL11A
chr13_-_40666600 1.82 ENST00000379561.6
forkhead box O1
chr11_-_32435529 1.81 ENST00000448076.9
ENST00000452863.10
WT1 transcription factor
chr7_-_140924900 1.80 ENST00000646891.1
ENST00000644969.2
B-Raf proto-oncogene, serine/threonine kinase
chr6_+_35342614 1.78 ENST00000337400.6
ENST00000311565.4
peroxisome proliferator activated receptor delta
chr7_-_98869920 1.77 ENST00000345589.4
transmembrane protein 130
chr16_-_89490479 1.74 ENST00000642600.1
ENST00000301030.10
ankyrin repeat domain 11
chr9_-_98255553 1.74 ENST00000375064.5
TBC1 domain family member 2
chr5_-_11904417 1.74 ENST00000304623.13
catenin delta 2
chr8_-_144103678 1.73 ENST00000398712.7
SHANK associated RH domain interactor
chr13_+_111153708 1.72 ENST00000218789.9
Rho guanine nucleotide exchange factor 7
chr19_+_36054879 1.72 ENST00000378860.8
ENST00000427823.3
ENST00000681542.1
ENST00000680321.1
ENST00000680359.1
ENST00000680403.1
ENST00000679714.1
ENST00000679682.1
ENST00000401500.7
ENST00000680564.1
WD repeat domain 62
chr5_-_88883701 1.71 ENST00000636998.1
myocyte enhancer factor 2C
chr13_-_36131286 1.70 ENST00000255448.8
ENST00000379892.4
doublecortin like kinase 1
chr10_-_116742584 1.69 ENST00000674205.1
heat shock protein family A (Hsp70) member 12A
chr10_-_116742559 1.69 ENST00000674344.1
ENST00000369209.8
ENST00000674459.1
heat shock protein family A (Hsp70) member 12A
chr7_-_17940468 1.69 ENST00000611725.4
ENST00000409604.1
ENST00000428135.7
sorting nexin 13
chr10_-_77637789 1.66 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr11_-_72642407 1.66 ENST00000376450.7
phosphodiesterase 2A
chr13_+_21140572 1.65 ENST00000607003.5
ENST00000492245.5
Sin3A associated protein 18
chr13_+_21140514 1.64 ENST00000382533.8
ENST00000621421.4
Sin3A associated protein 18
chr8_-_133571857 1.64 ENST00000522652.6
ENST00000648219.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr8_-_133571909 1.64 ENST00000521180.5
ENST00000517668.5
ENST00000399640.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr10_-_133308817 1.63 ENST00000543663.6
tubulin gamma complex associated protein 2
chr11_-_72642450 1.62 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr15_+_84981981 1.62 ENST00000339708.9
phosphodiesterase 8A
chr21_+_37006693 1.62 ENST00000329553.3
ripply transcriptional repressor 3
chr11_+_64035925 1.60 ENST00000682287.1
fibronectin leucine rich transmembrane protein 1
chrX_-_38327496 1.59 ENST00000642395.2
ENST00000645032.1
ENST00000644238.1
ENST00000642558.1
ENST00000339363.7
ENST00000644337.1
ENST00000647261.1
retinitis pigmentosa GTPase regulator
chr11_-_2141238 1.58 ENST00000434045.6
insulin like growth factor 2
chr7_-_98870006 1.58 ENST00000339375.9
transmembrane protein 130
chr17_-_4641670 1.55 ENST00000293761.8
arachidonate 15-lipoxygenase
chr11_-_2140967 1.54 ENST00000381389.5
insulin like growth factor 2
chr11_+_62337424 1.52 ENST00000415229.6
ENST00000301776.9
ENST00000628829.2
ENST00000534571.5
ENST00000526096.2
asparaginase and isoaspartyl peptidase 1
chr18_+_44680093 1.51 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr22_+_18110305 1.51 ENST00000680175.1
ENST00000426208.5
tubulin alpha 8
chr14_-_100568475 1.50 ENST00000553553.6
brain enriched guanylate kinase associated
chr4_-_145180496 1.47 ENST00000447906.8
OTU deubiquitinase 4
chr16_+_56191476 1.47 ENST00000262493.12
G protein subunit alpha o1
chrX_+_154458274 1.46 ENST00000369682.4
plexin A3
chr19_+_17967072 1.44 ENST00000684775.1
ENST00000615435.2
ENST00000683588.1
ENST00000684725.1
ENST00000682421.1
potassium calcium-activated channel subfamily N member 1
chr11_-_63768762 1.42 ENST00000433688.2
chromosome 11 open reading frame 95
chr17_-_78840647 1.40 ENST00000587783.5
ENST00000542802.7
ENST00000586531.5
ENST00000589424.5
ENST00000590546.6
ubiquitin specific peptidase 36
chr17_+_30831944 1.40 ENST00000321990.5
ATPase family AAA domain containing 5
chr19_-_44500503 1.37 ENST00000587047.1
ENST00000391956.8
ENST00000221327.8
ENST00000592529.6
ENST00000591064.1
zinc finger protein 180
chr11_+_1389895 1.36 ENST00000308219.13
ENST00000531197.5
ENST00000528841.6
BR serine/threonine kinase 2
chr21_+_46324081 1.36 ENST00000359568.10
pericentrin
chr19_+_36054930 1.35 ENST00000679757.1
ENST00000270301.12
WD repeat domain 62
chr13_+_111153735 1.34 ENST00000375736.8
Rho guanine nucleotide exchange factor 7
chr17_+_76385256 1.33 ENST00000392496.3
sphingosine kinase 1
chr4_+_20251896 1.31 ENST00000504154.6
slit guidance ligand 2
chr4_-_106316181 1.30 ENST00000394706.7
ENST00000394708.7
TBC1 domain containing kinase
chr6_-_88963573 1.29 ENST00000369485.9
RNA guanylyltransferase and 5'-phosphatase
chr8_+_32548590 1.29 ENST00000652588.1
ENST00000521670.5
ENST00000287842.7
neuregulin 1
chr17_-_48613468 1.29 ENST00000498634.2
homeobox B8
chr8_+_135458027 1.29 ENST00000524199.5
KH RNA binding domain containing, signal transduction associated 3
chr17_-_1516621 1.29 ENST00000574561.1
inositol polyphosphate-5-phosphatase K
chr11_-_32435360 1.28 ENST00000639563.3
WT1 transcription factor
chr8_-_143160248 1.28 ENST00000342752.9
lymphocyte antigen 6 family member H
chr8_+_22245125 1.28 ENST00000306433.9
ENST00000519237.5
ENST00000397802.8
RNA polymerase III subunit D
chr16_-_2135898 1.24 ENST00000262304.9
ENST00000423118.5
polycystin 1, transient receptor potential channel interacting
chr14_-_75981986 1.24 ENST00000238682.8
transforming growth factor beta 3
chr2_-_60553558 1.23 ENST00000642439.1
ENST00000356842.9
BAF chromatin remodeling complex subunit BCL11A
chr10_-_133308844 1.23 ENST00000682905.1
ENST00000682515.1
ENST00000683612.1
ENST00000252936.8
ENST00000417178.7
ENST00000682161.1
ENST00000683014.1
ENST00000683060.1
ENST00000683383.1
tubulin gamma complex associated protein 2
chr10_-_102419934 1.22 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr17_-_44199834 1.21 ENST00000587097.6
ataxin 7 like 3
chr7_-_108003122 1.20 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr5_+_36606355 1.20 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr5_-_132830611 1.20 ENST00000378679.8
ENST00000440118.1
shroom family member 1
chr17_-_78840881 1.18 ENST00000312010.10
ubiquitin specific peptidase 36
chr6_+_35342535 1.18 ENST00000360694.8
ENST00000418635.6
ENST00000448077.6
peroxisome proliferator activated receptor delta
chr5_-_128537821 1.16 ENST00000508989.5
fibrillin 2
chr6_+_44387686 1.13 ENST00000371477.4
cell division cycle 5 like
chr19_+_49119531 1.10 ENST00000334186.9
PTPRF interacting protein alpha 3
chr17_-_1516699 1.10 ENST00000320345.10
ENST00000406424.8
inositol polyphosphate-5-phosphatase K
chr1_-_212035513 1.09 ENST00000366992.7
ENST00000366993.7
ENST00000440600.6
ENST00000366994.8
integrator complex subunit 7
chr7_+_149262165 1.09 ENST00000434415.6
zinc finger family member 783
chr12_+_51907478 1.04 ENST00000388922.9
activin A receptor like type 1
chr12_+_7130341 1.02 ENST00000266546.11
calsyntenin 3
chr3_-_156555083 1.01 ENST00000265044.7
ENST00000476217.5
signal sequence receptor subunit 3
chr10_+_122374685 1.01 ENST00000368990.7
ENST00000368989.6
ENST00000463663.6
pleckstrin homology domain containing A1
chr12_-_96400067 0.99 ENST00000542666.5
cyclin dependent kinase 17
chr11_+_28110275 0.99 ENST00000303459.10
ENST00000634762.1
ENST00000634721.1
methyltransferase like 15
chr20_+_58692767 0.99 ENST00000356091.11
aminopeptidase like 1
chr16_+_56191728 0.97 ENST00000638705.1
ENST00000262494.12
G protein subunit alpha o1
chr1_+_39491618 0.95 ENST00000331593.6
bone morphogenetic protein 8a
chr4_+_147480917 0.95 ENST00000324300.10
ENST00000358556.8
ENST00000511804.5
ENST00000648866.1
endothelin receptor type A
chr7_-_76627240 0.92 ENST00000275569.8
ENST00000310842.9
POM121 and ZP3 fusion
chr17_+_17303319 0.88 ENST00000616989.1
ENST00000389022.9
5',3'-nucleotidase, mitochondrial
chr1_-_16237146 0.87 ENST00000375599.8
ciliogenesis and planar polarity effector 2
chr17_-_4641895 0.87 ENST00000574640.1
arachidonate 15-lipoxygenase
chr2_-_60553618 0.86 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BAF chromatin remodeling complex subunit BCL11A
chr15_-_83284645 0.84 ENST00000345382.7
basonuclin 1
chr16_-_29995601 0.84 ENST00000279392.8
ENST00000564026.1
HIRA interacting protein 3
chr5_-_143403611 0.84 ENST00000394464.7
ENST00000231509.7
nuclear receptor subfamily 3 group C member 1
chr13_-_99086611 0.83 ENST00000427887.2
dedicator of cytokinesis 9
chrX_+_155071414 0.83 ENST00000340647.8
BRCA1/BRCA2-containing complex subunit 3
chrX_-_53684119 0.83 ENST00000342160.7
ENST00000446750.1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr22_-_19854807 0.83 ENST00000416337.1
ENST00000403325.5
ENST00000453108.1
retrotransposon Gag like 10
G protein subunit beta 1 like
chr10_-_77637444 0.82 ENST00000639205.1
ENST00000639498.1
ENST00000372408.7
ENST00000372403.9
ENST00000640626.1
ENST00000404857.6
ENST00000638252.1
ENST00000640029.1
ENST00000640934.1
ENST00000639823.1
ENST00000372437.6
ENST00000639344.1
potassium calcium-activated channel subfamily M alpha 1
chr6_-_110815408 0.82 ENST00000368911.8
cyclin dependent kinase 19
chr10_-_61001430 0.82 ENST00000357917.4
Rho related BTB domain containing 1
chr19_-_16542415 0.80 ENST00000198939.6
ENST00000546361.7
calcium homeostasis endoplasmic reticulum protein
chr3_-_48898813 0.79 ENST00000319017.5
ENST00000430379.5
solute carrier family 25 member 20
chr22_-_19854862 0.78 ENST00000329517.11
ENST00000405009.5
ENST00000328554.9
ENST00000405640.1
ENST00000407472.5
G protein subunit beta 1 like
retrotransposon Gag like 10
chr5_-_115262851 0.77 ENST00000379615.3
ENST00000419445.6
protein geranylgeranyltransferase type I subunit beta
chr17_-_1516601 0.76 ENST00000421807.7
ENST00000477910.5
ENST00000575172.5
inositol polyphosphate-5-phosphatase K
chr11_+_62613236 0.76 ENST00000278833.4
retinal outer segment membrane protein 1
chr2_+_120013068 0.75 ENST00000443902.6
ENST00000263713.10
erythrocyte membrane protein band 4.1 like 5
chr17_-_81911367 0.75 ENST00000538936.7
ENST00000538721.6
ENST00000573636.6
ENST00000571105.5
ENST00000576343.5
ENST00000572473.1
phosphate cytidylyltransferase 2, ethanolamine
chr1_-_94237562 0.75 ENST00000260526.11
ENST00000370217.3
Rho GTPase activating protein 29
chr11_+_3855629 0.75 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr14_-_92106535 0.73 ENST00000526872.3
ENST00000532032.5
ENST00000506466.5
ENST00000554592.5
ENST00000555381.5
ENST00000553491.5
ENST00000556220.5
ENST00000557311.6
ENST00000617719.4
ENST00000554672.6
ENST00000644486.2
ENST00000502250.5
ENST00000503767.5
ataxin 3
chr14_+_90061979 0.71 ENST00000282146.5
potassium two pore domain channel subfamily K member 13
chr8_+_28701487 0.71 ENST00000220562.9
exostosin like glycosyltransferase 3
chr9_+_128456899 0.70 ENST00000372791.7
outer dense fiber of sperm tails 2
chr22_-_21867368 0.70 ENST00000544786.1
mitogen-activated protein kinase 1
chr2_-_169362527 0.69 ENST00000649046.1
ENST00000443831.1
LDL receptor related protein 2
chr12_+_12357056 0.68 ENST00000314565.9
ENST00000542728.5
BLOC-1 related complex subunit 5
chr9_+_93451884 0.67 ENST00000375389.7
family with sequence similarity 120A
chr5_-_181261078 0.66 ENST00000611618.1
tripartite motif containing 52
chr19_-_821929 0.66 ENST00000359894.6
ENST00000520876.8
ENST00000519502.2
phospholipid phosphatase related 3
chr15_+_63042632 0.66 ENST00000288398.10
ENST00000358278.7
ENST00000610733.1
ENST00000403994.9
ENST00000357980.9
ENST00000559556.5
ENST00000267996.11
ENST00000559397.6
ENST00000561266.6
ENST00000560970.6
tropomyosin 1
chr9_+_136807911 0.66 ENST00000371671.9
ENST00000311502.12
ENST00000371663.10
RAB, member RAS oncogene family like 6
chr9_-_112332962 0.65 ENST00000458258.5
ENST00000210227.4
polypyrimidine tract binding protein 3
chr22_+_18110802 0.64 ENST00000330423.8
tubulin alpha 8
chr3_-_38649668 0.64 ENST00000333535.9
ENST00000413689.6
ENST00000423572.7
sodium voltage-gated channel alpha subunit 5
chr4_+_147481085 0.63 ENST00000651419.1
endothelin receptor type A
chr19_-_1812194 0.62 ENST00000525591.5
ATPase phospholipid transporting 8B3
chr4_+_55346213 0.62 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr20_-_41317602 0.61 ENST00000559234.5
ENST00000683867.1
zinc fingers and homeoboxes 3
chr13_+_25301587 0.60 ENST00000381736.8
ENST00000463407.5
ENST00000381718.7
ENST00000381747.7
nucleoporin 58
chr3_+_139935176 0.60 ENST00000458420.7
calsyntenin 2
chr17_-_57955242 0.55 ENST00000577840.5
CUE domain containing 1
chr6_+_146029486 0.55 ENST00000507907.1
glutamate metabotropic receptor 1
chr16_+_1153098 0.55 ENST00000348261.11
calcium voltage-gated channel subunit alpha1 H
chr4_-_81215185 0.51 ENST00000264399.6
protein kinase cGMP-dependent 2
chr12_+_2053545 0.50 ENST00000682336.1
ENST00000344100.7
ENST00000399591.5
ENST00000399595.5
ENST00000399597.5
ENST00000399601.5
ENST00000399606.5
ENST00000399621.5
ENST00000399629.5
ENST00000399637.5
ENST00000399638.5
ENST00000399644.5
ENST00000399649.5
ENST00000402845.7
ENST00000682686.1
calcium voltage-gated channel subunit alpha1 C
chr14_+_64504574 0.50 ENST00000358738.3
zinc finger and BTB domain containing 1
chr14_-_92106607 0.50 ENST00000340660.10
ENST00000393287.9
ENST00000429774.6
ENST00000545170.5
ENST00000620536.4
ENST00000621269.4
ataxin 3
chr16_+_70523782 0.50 ENST00000566095.6
ENST00000577085.1
ENST00000302516.10
ENST00000567654.1
splicing factor 3b subunit 3
chr1_-_39691393 0.49 ENST00000372844.8
hippocalcin like 4
chr1_-_39691450 0.47 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr5_-_132737518 0.47 ENST00000403231.6
ENST00000378735.5
ENST00000618515.4
ENST00000378746.8
kinesin family member 3A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.6 GO:0032595 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
2.3 6.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.5 7.6 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
1.1 5.7 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.1 3.4 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
1.1 3.3 GO:0046521 sphingoid catabolic process(GO:0046521)
1.0 3.1 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
1.0 3.9 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.8 3.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.8 9.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.8 4.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.8 2.4 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.8 2.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.8 2.4 GO:1901074 cellular response to interleukin-13(GO:0035963) regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.8 4.7 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.7 2.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.7 10.2 GO:0043589 skin morphogenesis(GO:0043589)
0.7 6.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.7 4.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 1.8 GO:1902617 response to fluoride(GO:1902617)
0.6 2.9 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.6 4.0 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.4 1.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.4 3.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.4 1.2 GO:1905073 uterine wall breakdown(GO:0042704) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.4 3.1 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.4 1.9 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.3 1.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 1.2 GO:0072237 metanephric proximal tubule development(GO:0072237)
0.3 1.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3 0.9 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.3 1.1 GO:1990637 response to prolactin(GO:1990637)
0.3 3.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.2 3.0 GO:2000288 negative regulation of collagen biosynthetic process(GO:0032966) positive regulation of myoblast proliferation(GO:2000288)
0.2 3.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 1.6 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.2 2.8 GO:0034465 response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.2 3.2 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.2 1.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.6 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 2.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 1.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.7 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.2 1.5 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 3.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.5 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.6 GO:0019348 polyprenol catabolic process(GO:0016095) dolichol metabolic process(GO:0019348)
0.2 0.8 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.9 GO:0035803 egg coat formation(GO:0035803)
0.1 0.4 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 1.2 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 1.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.8 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.0 GO:0070475 rRNA base methylation(GO:0070475)
0.1 2.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.0 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 1.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 7.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 3.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 3.1 GO:0007099 centriole replication(GO:0007099)
0.1 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 1.3 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 4.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.9 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 3.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 2.4 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 2.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.8 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 2.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.4 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 1.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 2.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 3.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.2 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 1.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.6 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.6 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0072384 organelle transport along microtubule(GO:0072384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7 2.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.7 16.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 4.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.4 1.2 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 3.1 GO:0000322 storage vacuole(GO:0000322)
0.4 5.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 1.7 GO:0071797 LUBAC complex(GO:0071797)
0.3 0.8 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.2 2.3 GO:0061574 ASAP complex(GO:0061574)
0.2 9.9 GO:0030673 axolemma(GO:0030673)
0.2 1.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 2.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.6 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.2 2.1 GO:0016013 syntrophin complex(GO:0016013)
0.2 2.1 GO:0030008 TRAPP complex(GO:0030008)
0.2 0.7 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.5 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 1.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 6.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 5.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 6.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 3.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 4.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 7.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 4.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)
0.0 5.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0032184 SUMO polymer binding(GO:0032184)
1.1 3.4 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
1.0 5.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.8 2.4 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.8 10.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.7 26.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 3.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 3.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 1.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.4 13.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 2.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 2.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 1.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 3.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.3 5.7 GO:0051787 misfolded protein binding(GO:0051787)
0.3 0.8 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3 0.8 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.2 1.0 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 1.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 3.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.3 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.6 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 1.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 0.9 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 0.8 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 4.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 2.5 GO:0050693 LBD domain binding(GO:0050693)
0.2 2.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.7 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 4.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 4.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 3.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 4.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 3.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 1.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 3.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 2.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 9.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 8.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 4.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 5.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 6.2 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 4.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 6.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.0 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 9.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 8.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 6.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 9.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 4.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 2.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 4.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 4.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 3.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 18.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 3.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 2.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 4.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 4.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 5.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 2.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases