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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HMBOX1

Z-value: 4.97

Motif logo

Transcription factors associated with HMBOX1

Gene Symbol Gene ID Gene Info
ENSG00000147421.18 HMBOX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMBOX1hg38_v1_chr8_+_28890365_28890421-0.343.4e-07Click!

Activity profile of HMBOX1 motif

Sorted Z-values of HMBOX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMBOX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_152036984 29.27 ENST00000271638.3
S100 calcium binding protein A11
chr6_+_27147094 27.68 ENST00000377459.3
H2A clustered histone 12
chr3_+_33114033 20.26 ENST00000449224.1
cartilage associated protein
chrX_-_20218941 16.18 ENST00000457145.6
ribosomal protein S6 kinase A3
chr14_+_55611977 15.96 ENST00000395309.7
ENST00000413890.6
kinectin 1
chr9_+_73151833 15.87 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
annexin A1
chr3_-_149377637 14.51 ENST00000305366.8
transmembrane 4 L six family member 1
chr1_+_40988513 14.12 ENST00000649215.1
CTP synthase 1
chr14_+_34993240 13.31 ENST00000677647.1
signal recognition particle 54
chr6_-_8102481 13.08 ENST00000502429.5
ENST00000429723.6
ENST00000379715.10
ENST00000507463.1
eukaryotic translation elongation factor 1 epsilon 1
chr19_+_16067526 12.80 ENST00000646974.2
tropomyosin 4
chrX_-_10833643 12.44 ENST00000380785.5
ENST00000380787.5
midline 1
chr2_-_99336306 11.82 ENST00000264255.8
ENST00000409434.5
ENST00000434323.5
thioredoxin domain containing 9
chr14_-_55191534 11.75 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr18_-_36798482 11.68 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr1_-_31919093 11.54 ENST00000602683.5
ENST00000470404.5
protein tyrosine phosphatase 4A2
chr5_+_96743578 11.44 ENST00000325674.11
calpastatin
chr1_-_224434750 11.17 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr6_+_138404206 10.44 ENST00000607197.6
ENST00000367697.7
heme binding protein 2
chr8_+_11809135 10.40 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chrX_-_10620419 10.35 ENST00000380782.6
midline 1
chr1_-_150697128 10.15 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr15_+_79311084 9.62 ENST00000299705.10
transmembrane p24 trafficking protein 3
chr1_+_236394268 9.50 ENST00000334232.9
EDAR associated death domain
chr9_+_99222258 9.36 ENST00000223641.5
SEC61 translocon subunit beta
chr8_+_30387064 9.34 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr5_-_134632769 9.23 ENST00000505758.5
ENST00000439578.5
ENST00000502286.1
ENST00000402673.7
secretion associated Ras related GTPase 1B
chr17_-_41982321 9.09 ENST00000587727.6
DnaJ heat shock protein family (Hsp40) member C7
chr4_-_102868869 9.07 ENST00000338145.7
ENST00000357194.10
ubiquitin conjugating enzyme E2 D3
chrX_-_10620534 8.70 ENST00000317552.9
midline 1
chr11_-_47426419 8.54 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr7_+_135557904 8.48 ENST00000285968.11
nucleoporin 205
chr6_-_27146841 8.22 ENST00000356950.2
H2B clustered histone 12
chr17_-_3668557 8.10 ENST00000225525.4
Tax1 binding protein 3
chrX_+_71283186 7.91 ENST00000535149.5
non-POU domain containing octamer binding
chr1_+_207770322 7.54 ENST00000462968.2
CD46 molecule
chrX_+_110003095 7.29 ENST00000372073.5
ENST00000372068.7
ENST00000288381.4
transmembrane protein 164
chr17_-_3668640 7.25 ENST00000611779.4
Tax1 binding protein 3
chr7_+_134891566 7.04 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr10_+_74176537 6.90 ENST00000672394.1
adenosine kinase
chr20_-_44504850 6.77 ENST00000411544.5
serine incorporator 3
chr4_-_47463649 6.74 ENST00000381571.6
COMM domain containing 8
chr6_+_30617825 6.48 ENST00000259873.5
mitochondrial ribosomal protein S18B
chr7_+_99408958 6.45 ENST00000222969.10
BUD31 homolog
chr12_+_64497968 6.21 ENST00000676593.1
ENST00000677093.1
TANK binding kinase 1
novel transcript
chr7_+_134891400 5.94 ENST00000393118.6
caldesmon 1
chr7_+_101817601 5.91 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr5_-_69369988 5.86 ENST00000380818.7
ENST00000328663.8
adenylate kinase 6
TATA-box binding protein associated factor 9
chr20_-_50153637 5.84 ENST00000341698.2
ENST00000371652.9
ENST00000371650.9
PEDS1-UBE2V1 readthrough
plasmanylethanolamine desaturase 1
chr10_+_74176741 5.82 ENST00000673027.1
ENST00000372734.5
ENST00000541550.6
adenosine kinase
chr10_+_123154364 5.77 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr5_-_69369257 5.59 ENST00000509462.5
TATA-box binding protein associated factor 9
chr3_+_36993798 5.58 ENST00000455445.6
ENST00000539477.6
ENST00000435176.5
ENST00000429117.5
ENST00000441265.6
mutL homolog 1
chr17_+_3668803 5.37 ENST00000248378.6
ENST00000397133.2
ER membrane protein complex subunit 6
chr7_+_95485898 5.34 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr7_+_128739292 5.25 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
calumenin
chr1_+_117060309 4.94 ENST00000369466.9
transcription termination factor 2
chr11_+_10751203 4.72 ENST00000361367.7
CTR9 homolog, Paf1/RNA polymerase II complex component
chr2_+_86907953 4.38 ENST00000409776.6
RANBP2 like and GRIP domain containing 1
chr10_+_35195843 4.22 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr12_-_32755876 4.03 ENST00000324868.13
tyrosyl-tRNA synthetase 2
chr1_-_26890237 3.81 ENST00000431781.2
ENST00000374135.9
GPN-loop GTPase 2
chr5_-_78549151 3.70 ENST00000515007.6
LHFPL tetraspan subfamily member 2
chr15_-_40038895 3.69 ENST00000558720.5
signal recognition particle 14
chr10_-_32935511 3.55 ENST00000423113.5
integrin subunit beta 1
chr12_+_56128217 3.49 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr11_+_57763820 3.44 ENST00000674106.1
catenin delta 1
chr7_+_101085464 3.38 ENST00000306085.11
ENST00000412507.1
tripartite motif containing 56
chr15_+_78873723 3.38 ENST00000559690.5
ENST00000559158.5
mortality factor 4 like 1
chr16_+_22297375 3.37 ENST00000615879.4
ENST00000299853.10
ENST00000564209.5
ENST00000565358.5
ENST00000418581.6
ENST00000564883.5
ENST00000359210.8
ENST00000563024.5
RNA polymerase III subunit E
chrX_+_71283577 3.37 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chr11_-_58578096 3.37 ENST00000528954.5
ENST00000528489.1
leupaxin
chr7_+_107580454 3.36 ENST00000379117.6
ENST00000473124.1
B cell receptor associated protein 29
chr1_+_174875505 3.36 ENST00000486220.5
RAB GTPase activating protein 1 like
chr2_-_27409523 3.36 ENST00000344034.5
protein phosphatase, Mg2+/Mn2+ dependent 1G
chr3_-_93973933 3.35 ENST00000650591.1
protein S
chr9_+_125748175 3.33 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr14_+_67240713 3.31 ENST00000677382.1
membrane palmitoylated protein 5
chr7_+_128455849 3.27 ENST00000435296.2
ENST00000257696.5
hypoxia inducible lipid droplet associated
chr16_-_67247460 3.26 ENST00000258201.9
formin homology 2 domain containing 1
chr2_+_27771700 3.19 ENST00000379666.7
ENST00000296102.8
mitochondrial ribosomal protein L33
chr2_+_68157877 3.18 ENST00000263657.7
partner of NOB1 homolog
chr14_-_75069478 3.08 ENST00000555463.1
acylphosphatase 1
chr3_+_33114007 3.03 ENST00000320954.11
cartilage associated protein
chr11_-_57427474 2.97 ENST00000533235.5
ENST00000526621.5
ENST00000352187.5
solute carrier family 43 member 3
chr12_+_51239278 2.88 ENST00000551313.1
DAZ associated protein 2
chr2_+_161231078 2.86 ENST00000439442.1
TRAF family member associated NFKB activator
chr20_-_2664186 2.84 ENST00000474315.5
ENST00000380843.9
ENST00000380851.9
ENST00000613370.1
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chr14_+_89955895 2.79 ENST00000393452.7
ENST00000554180.5
ENST00000335725.9
ENST00000393454.6
ENST00000553617.5
ENST00000556867.1
ENST00000553527.1
tyrosyl-DNA phosphodiesterase 1
chr10_+_87659839 2.77 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_+_108719473 2.68 ENST00000283195.11
RAN binding protein 2
chr5_-_138331770 2.67 ENST00000415130.6
ENST00000323760.11
ENST00000503022.5
cell division cycle 25C
chr1_-_109740304 2.64 ENST00000540225.2
glutathione S-transferase mu 3
chrX_+_103628959 2.55 ENST00000372625.8
ENST00000372624.3
transcription elongation factor A like 1
chr8_-_94436926 2.45 ENST00000481490.3
fibrinogen silencer binding protein
chr11_-_31806886 2.42 ENST00000640963.1
paired box 6
chrX_-_75156272 2.38 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ATP binding cassette subfamily B member 7
chr14_+_64388296 2.36 ENST00000554739.5
ENST00000554768.6
ENST00000652179.1
ENST00000652337.1
ENST00000557370.3
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
chr6_-_73520170 2.36 ENST00000678508.1
eukaryotic translation elongation factor 1 alpha 1
chr17_-_10549652 2.29 ENST00000245503.10
myosin heavy chain 2
chr1_-_92792396 2.22 ENST00000370331.5
ENST00000540033.2
ecotropic viral integration site 5
chr4_+_56907876 2.19 ENST00000640168.2
ENST00000309042.12
RE1 silencing transcription factor
chr6_+_26199509 2.13 ENST00000356530.5
H2B clustered histone 7
chr14_-_70416994 2.13 ENST00000621525.4
ENST00000256366.6
SYNJ2BP-COX16 readthrough
synaptojanin 2 binding protein
chr17_-_10549612 2.12 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr14_-_50532590 2.10 ENST00000013125.9
mitogen-activated protein kinase kinase kinase kinase 5
chr5_+_139293728 2.02 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr8_+_55102012 2.02 ENST00000327381.7
XK related 4
chr14_+_104865256 2.00 ENST00000414716.8
ENST00000556508.5
ENST00000453495.2
centrosomal protein 170B
chr1_-_167518583 2.00 ENST00000392122.3
CD247 molecule
chr22_-_36776067 1.92 ENST00000417951.6
ENST00000433985.7
ENST00000430701.5
intraflagellar transport 27
chr1_-_110391041 1.90 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr4_-_109801978 1.86 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr17_-_5486157 1.84 ENST00000572834.5
ENST00000158771.9
ENST00000570848.5
ENST00000571971.1
derlin 2
chr10_-_5003850 1.77 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr12_+_53098846 1.76 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr5_-_16916400 1.76 ENST00000513882.5
myosin X
chr14_-_23154369 1.69 ENST00000453702.5
solute carrier family 7 member 8
chr1_+_23959797 1.67 ENST00000374468.1
ENST00000334351.8
proline rich nuclear receptor coactivator 2
chr16_-_71809049 1.66 ENST00000569748.5
ENST00000570017.1
ENST00000393512.7
adaptor related protein complex 1 subunit gamma 1
chr1_+_116111395 1.63 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr11_+_65576023 1.59 ENST00000533237.5
ENST00000309295.9
ENST00000634639.1
EH domain binding protein 1 like 1
chr4_-_139084289 1.58 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chr22_-_19431692 1.51 ENST00000340170.8
ENST00000263208.5
histone cell cycle regulator
chr10_-_52771700 1.47 ENST00000373968.3
mannose binding lectin 2
chr22_-_36776147 1.45 ENST00000340630.9
intraflagellar transport 27
chr4_-_158159657 1.40 ENST00000590648.5
golgi associated kinase 1B
chrX_+_71533095 1.36 ENST00000373719.8
ENST00000373701.7
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_-_55296361 1.35 ENST00000647547.1
coiled-coil domain containing 88A
chr17_-_58417521 1.25 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr9_-_120793377 1.24 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
F-box and WD repeat domain containing 2
chr9_-_120793343 1.23 ENST00000684047.1
F-box and WD repeat domain containing 2
chr1_-_167518521 1.23 ENST00000362089.10
CD247 molecule
chr3_-_121749704 1.22 ENST00000393667.7
ENST00000340645.9
ENST00000614479.4
golgin B1
chr17_-_10549694 1.21 ENST00000622564.4
myosin heavy chain 2
chr1_-_25859352 1.20 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr11_+_117327829 1.18 ENST00000533153.5
ENST00000278935.8
ENST00000525416.5
centrosomal protein 164
chr17_-_58417547 1.10 ENST00000577716.5
ring finger protein 43
chr2_-_213151590 1.03 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr14_-_50532518 1.03 ENST00000682126.1
mitogen-activated protein kinase kinase kinase kinase 5
chr14_+_22281097 1.02 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr16_-_71808803 1.01 ENST00000563104.5
ENST00000569975.5
ENST00000565412.5
ENST00000567583.1
ENST00000299980.9
adaptor related protein complex 1 subunit gamma 1
chr2_+_46542474 0.93 ENST00000238738.9
ras homolog family member Q
chr4_+_73481737 0.92 ENST00000226355.5
afamin
chr1_+_206470463 0.87 ENST00000581977.7
ENST00000578328.6
ENST00000584998.5
ENST00000579827.6
inhibitor of nuclear factor kappa B kinase subunit epsilon
chr17_-_1492660 0.84 ENST00000648651.1
myosin IC
chr16_-_30585497 0.79 ENST00000567773.1
ENST00000395216.3
ENST00000470110.2
zinc finger protein 785
chr1_-_217076889 0.74 ENST00000493748.5
ENST00000463665.5
estrogen related receptor gamma
chr11_-_31807617 0.74 ENST00000639920.1
ENST00000640460.1
paired box 6
chr11_-_62805429 0.69 ENST00000294172.7
ENST00000531131.1
ENST00000530875.5
ENST00000531709.6
nuclear RNA export factor 1
chr18_-_66604076 0.63 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr5_+_93583212 0.56 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chrX_-_21758097 0.55 ENST00000379494.4
small muscle protein X-linked
chr12_+_67648737 0.53 ENST00000344096.4
ENST00000393555.3
dual specificity tyrosine phosphorylation regulated kinase 2
chr1_-_197067234 0.48 ENST00000367412.2
coagulation factor XIII B chain
chr4_+_73436198 0.47 ENST00000395792.7
alpha fetoprotein
chr7_-_123199960 0.44 ENST00000194130.7
solute carrier family 13 member 1
chr12_-_10810168 0.41 ENST00000240691.4
taste 2 receptor member 9
chr8_+_67064316 0.36 ENST00000675306.2
ENST00000678017.1
ENST00000262210.11
ENST00000675869.1
ENST00000677009.1
ENST00000676847.1
ENST00000676471.1
ENST00000678542.1
ENST00000677619.1
ENST00000676605.1
ENST00000678553.1
ENST00000674993.1
ENST00000678318.1
ENST00000676573.1
ENST00000676317.1
ENST00000677592.1
ENST00000679226.1
ENST00000675955.1
ENST00000676882.1
ENST00000678616.1
ENST00000678645.1
ENST00000678747.1
centrosome and spindle pole associated protein 1
chr17_-_37643422 0.35 ENST00000617633.5
DExD-box helicase 52
chr12_-_68225806 0.35 ENST00000229134.5
interleukin 26
chr3_+_52410635 0.32 ENST00000327906.8
PHD finger protein 7
chr12_-_10435940 0.27 ENST00000381901.5
ENST00000381902.7
ENST00000539033.1
killer cell lectin like receptor C2
novel protein
chrX_+_136648138 0.27 ENST00000370629.7
CD40 ligand
chr2_+_102001966 0.26 ENST00000457817.5
interleukin 1 receptor type 2
chr18_-_21703688 0.26 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr20_+_44582549 0.25 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr1_+_175067831 0.23 ENST00000239462.9
tenascin N
chr5_+_132369691 0.22 ENST00000245407.8
solute carrier family 22 member 5
chr13_+_76992412 0.16 ENST00000636705.1
CLN5 intracellular trafficking protein
chr4_+_9170409 0.09 ENST00000512047.2
family with sequence similarity 90 member A26
chr12_+_28190420 0.09 ENST00000539107.5
ENST00000545336.5
coiled-coil domain containing 91
chr8_-_123737378 0.08 ENST00000419625.6
ENST00000262219.10
annexin A13
chr12_+_4649097 0.05 ENST00000648836.1
ENST00000266544.10
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr10_+_122560751 0.04 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr12_-_32896757 0.03 ENST00000070846.11
ENST00000340811.9
plakophilin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.3 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
5.3 15.9 GO:0036292 DNA rewinding(GO:0036292)
3.5 14.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
3.3 13.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
3.2 12.7 GO:0009216 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
3.1 9.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
3.0 11.8 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
2.2 31.5 GO:0035372 protein localization to microtubule(GO:0035372)
2.1 6.2 GO:0044565 dendritic cell proliferation(GO:0044565)
2.0 11.8 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
1.7 10.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.6 4.7 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
1.4 5.6 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
1.3 3.8 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.1 11.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.1 3.3 GO:0035425 autocrine signaling(GO:0035425)
1.0 10.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.9 13.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.9 2.8 GO:0000103 sulfate assimilation(GO:0000103)
0.9 10.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.9 2.7 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.9 2.6 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.8 6.8 GO:0009597 detection of virus(GO:0009597)
0.8 3.3 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.8 11.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.8 2.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.7 6.7 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.7 2.2 GO:2000740 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.7 3.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.7 3.3 GO:0007386 compartment pattern specification(GO:0007386)
0.6 15.4 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.6 2.4 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.6 4.0 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.5 9.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.5 9.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.5 3.6 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
0.5 11.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.5 16.2 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.5 2.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 2.7 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.4 8.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4 3.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.4 2.8 GO:0006102 isocitrate metabolic process(GO:0006102)
0.4 5.6 GO:0001778 plasma membrane repair(GO:0001778)
0.4 8.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 1.8 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 10.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.3 5.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 24.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 2.4 GO:0015886 heme transport(GO:0015886)
0.2 1.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 3.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 4.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 3.3 GO:0007097 nuclear migration(GO:0007097)
0.2 9.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 1.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 3.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 1.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 3.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 2.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 5.8 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 3.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 3.4 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 9.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 9.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 3.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 9.2 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 14.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.5 GO:0051873 complement activation, lectin pathway(GO:0001867) killing by host of symbiont cells(GO:0051873)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 3.2 GO:0070207 protein homotrimerization(GO:0070207)
0.1 3.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 3.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 1.5 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.1 1.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 5.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 16.0 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.3 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 5.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 3.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 0.4 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 3.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 2.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 1.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 7.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 3.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 11.8 GO:0006936 muscle contraction(GO:0006936)
0.0 3.5 GO:0006364 rRNA processing(GO:0006364)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.9 GO:0051180 vitamin transport(GO:0051180)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0044611 nuclear pore inner ring(GO:0044611)
2.6 15.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.5 7.5 GO:0002079 inner acrosomal membrane(GO:0002079)
2.2 13.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.9 5.8 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
1.9 17.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.8 9.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
1.8 5.4 GO:1903349 omegasome membrane(GO:1903349)
1.4 11.5 GO:0070761 pre-snoRNP complex(GO:0070761)
1.4 5.6 GO:0005715 late recombination nodule(GO:0005715)
1.3 11.3 GO:0042382 paraspeckles(GO:0042382)
1.2 3.6 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
1.1 5.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.9 12.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.9 2.7 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.9 13.0 GO:0030478 actin cap(GO:0030478)
0.9 8.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.6 11.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.5 5.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 4.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 5.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.4 4.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.4 31.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 1.8 GO:0048500 signal recognition particle(GO:0048500)
0.4 9.3 GO:0005685 U1 snRNP(GO:0005685)
0.3 3.3 GO:0032059 bleb(GO:0032059)
0.3 3.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 3.4 GO:0005915 zonula adherens(GO:0005915)
0.3 3.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.3 2.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 6.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 2.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 19.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 28.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 3.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 3.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.8 GO:0045160 myosin I complex(GO:0045160)
0.2 2.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.8 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 3.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 39.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 3.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.8 GO:0032433 filopodium tip(GO:0032433)
0.1 14.5 GO:0001650 fibrillar center(GO:0001650)
0.1 4.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 9.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 3.4 GO:0002102 podosome(GO:0002102)
0.1 11.8 GO:0030496 midbody(GO:0030496)
0.1 2.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0000346 transcription export complex(GO:0000346)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 3.8 GO:0005819 spindle(GO:0005819)
0.0 1.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 12.5 GO:0005768 endosome(GO:0005768)
0.0 11.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 14.1 GO:0003883 CTP synthase activity(GO:0003883)
3.2 12.7 GO:0004001 adenosine kinase activity(GO:0004001)
3.2 15.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.8 17.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
2.0 11.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.9 9.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.7 10.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
1.3 9.4 GO:0048408 epidermal growth factor binding(GO:0048408)
1.3 11.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.2 29.3 GO:0044548 S100 protein binding(GO:0044548)
1.1 11.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.9 8.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.9 2.8 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.7 2.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7 5.9 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.6 2.4 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.6 6.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5 3.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.5 2.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.5 5.6 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.5 10.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 3.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 16.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.4 9.9 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.8 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.3 18.6 GO:0019894 kinesin binding(GO:0019894)
0.3 0.9 GO:0032427 GBD domain binding(GO:0032427)
0.3 0.9 GO:0008431 vitamin E binding(GO:0008431)
0.3 2.4 GO:0015232 heme transporter activity(GO:0015232)
0.3 14.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 8.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 4.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 9.1 GO:0001671 ATPase activator activity(GO:0001671)
0.2 31.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 7.5 GO:0001848 complement binding(GO:0001848)
0.2 1.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 5.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 6.3 GO:0000146 microfilament motor activity(GO:0000146)
0.2 4.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 8.1 GO:0050699 WW domain binding(GO:0050699)
0.2 3.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 3.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 4.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 14.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 2.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.4 GO:0019534 toxin transporter activity(GO:0019534)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 8.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 10.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 2.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.2 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 15.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 3.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 4.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 3.3 GO:0043621 protein self-association(GO:0043621)
0.0 9.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 4.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 2.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 4.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 18.8 GO:0032403 protein complex binding(GO:0032403)
0.0 5.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 15.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 16.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 11.5 PID MYC PATHWAY C-MYC pathway
0.2 11.8 PID AURORA A PATHWAY Aurora A signaling
0.2 9.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 17.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.8 PID ATR PATHWAY ATR signaling pathway
0.1 3.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 27.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 3.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 5.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 3.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 4.2 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 13.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.5 12.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.5 25.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 9.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 23.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 16.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.3 7.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 11.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.3 7.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 9.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 10.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 4.0 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.2 3.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 17.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.2 2.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 5.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 5.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 5.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 3.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 2.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 17.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 0.7 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 3.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 14.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 5.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 4.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport