ISMARA results: HOXA6

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXA6

Z-value: 3.50

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Transcription factors associated with HOXA6

Gene Symbol	Gene ID	Gene Info
HOXA6 Ensembl NCBI GeneCards UniProt	ENSG00000106006.6	HOXA6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXA6	hg38_v1_chr7_-_27147774_27147774	0.38	9.3e-09	Click!

Activity profile of HOXA6 motif

Sorted Z-values of HOXA6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA6

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr3_+_41194741 Show fit	12.53	ENST00000643541.1 ENST00000426215.5 ENST00000645210.1 ENST00000646381.1 ENST00000405570.6 ENST00000642248.1 ENST00000433400.6	CTNNB1 Ensembl NCBI GeneCards UniProt Show fit	catenin beta 1
chr12_-_91182652 Show fit	12.11	ENST00000552145.5 ENST00000546745.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr12_-_16608183 Show fit	11.04	ENST00000354662.5 ENST00000538051.5	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr12_-_91182784 Show fit	10.87	ENST00000547568.6 ENST00000052754.10 ENST00000552962.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr12_-_16608073 Show fit	10.47	ENST00000441439.6	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr5_-_88883701 Show fit	9.02	ENST00000636998.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr17_-_55511434 Show fit	8.70	ENST00000636752.1	SMIM36 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 36
chr7_-_126533850 Show fit	8.01	ENST00000444921.3	GRM8 Ensembl NCBI GeneCards UniProt Show fit	glutamate metabotropic receptor 8
chr4_-_173530219 Show fit	7.76	ENST00000359562.4	HAND2 Ensembl NCBI GeneCards UniProt Show fit	heart and neural crest derivatives expressed 2
chr12_-_16605939 Show fit	7.36	ENST00000541295.5 ENST00000535535.5	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr12_-_16606102 Show fit	7.03	ENST00000537304.6	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr6_-_107824294 Show fit	6.94	ENST00000369020.8 ENST00000369022.6	SCML4 Ensembl NCBI GeneCards UniProt Show fit	Scm polycomb group protein like 4
chr18_-_55321986 Show fit	6.74	ENST00000570287.6	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr18_-_55322215 Show fit	6.42	ENST00000457482.7	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr7_-_42152444 Show fit	6.30	ENST00000479210.1	GLI3 Ensembl NCBI GeneCards UniProt Show fit	GLI family zinc finger 3
chr7_-_31340678 Show fit	6.27	ENST00000297142.4	NEUROD6 Ensembl NCBI GeneCards UniProt Show fit	neuronal differentiation 6
chr7_-_42152396 Show fit	6.26	ENST00000642432.1 ENST00000647255.1 ENST00000677288.1	GLI3 Ensembl NCBI GeneCards UniProt Show fit	GLI family zinc finger 3
chr5_-_88883420 Show fit	5.84	ENST00000437473.6	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr15_+_92900189 Show fit	5.72	ENST00000626874.2 ENST00000627622.1 ENST00000629346.2 ENST00000628375.2 ENST00000420239.7 ENST00000394196.9	CHD2 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 2
chr2_-_2324323 Show fit	5.20	ENST00000648339.1 ENST00000647694.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr17_-_40937445 Show fit	4.71	ENST00000436344.7 ENST00000485751.1	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr5_-_1882902 Show fit	4.52	ENST00000231357.7	IRX4 Ensembl NCBI GeneCards UniProt Show fit	iroquois homeobox 4
chr14_+_22508602 Show fit	4.47	ENST00000390504.1	TRAJ33 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 33
chr18_-_55351977 Show fit	4.38	ENST00000643689.1	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr2_+_66435558 Show fit	4.25	ENST00000488550.5	MEIS1 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 1
chr11_-_84923162 Show fit	4.23	ENST00000524982.5	DLG2 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 2
chr14_-_68794597 Show fit	4.22	ENST00000336440.3	ZFP36L1 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 1
chr7_-_27140195 Show fit	4.21	ENST00000522788.5 ENST00000317201.7	HOXA3 Ensembl NCBI GeneCards UniProt Show fit	homeobox A3
chr3_+_1093002 Show fit	4.20	ENST00000446702.7	CNTN6 Ensembl NCBI GeneCards UniProt Show fit	contactin 6
chr18_-_55587335 Show fit	4.15	ENST00000638154.3	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr7_-_27143672 Show fit	4.14	ENST00000222726.4	HOXA5 Ensembl NCBI GeneCards UniProt Show fit	homeobox A5
chr11_+_128694052 Show fit	4.05	ENST00000527786.7 ENST00000534087.3	FLI1 Ensembl NCBI GeneCards UniProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr12_-_16606795 Show fit	4.03	ENST00000447609.5	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr5_-_116574395 Show fit	3.99	ENST00000257414.12	SEMA6A Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6A
chr11_-_33892010 Show fit	3.86	ENST00000257818.3	LMO2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2
chr18_-_76495191 Show fit	3.86	ENST00000443185.7	ZNF516 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 516
chr5_-_161546671 Show fit	3.81	ENST00000517547.5	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr5_+_67004618 Show fit	3.70	ENST00000261569.11 ENST00000436277.5	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr5_-_161546708 Show fit	3.60	ENST00000393959.6	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr15_+_33968484 Show fit	3.39	ENST00000383263.7	CHRM5 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor muscarinic 5
chr1_+_167220870 Show fit	3.37	ENST00000367866.7 ENST00000429375.6 ENST00000541643.7	POU2F1 Ensembl NCBI GeneCards UniProt Show fit	POU class 2 homeobox 1
chr17_-_40937641 Show fit	3.30	ENST00000209718.8	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr15_-_70097852 Show fit	3.29	ENST00000559191.5	TLE3 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 3, transcriptional corepressor
chr18_-_55510753 Show fit	3.27	ENST00000543082.5	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr5_-_88883147 Show fit	3.26	ENST00000513252.5 ENST00000506554.5 ENST00000508569.5 ENST00000637732.1 ENST00000504921.7 ENST00000637481.1 ENST00000510942.5	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr18_-_55403682 Show fit	3.10	ENST00000564228.5 ENST00000630828.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr11_+_128693887 Show fit	3.09	ENST00000281428.12	FLI1 Ensembl NCBI GeneCards UniProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr5_+_171309239 Show fit	3.04	ENST00000296921.6	TLX3 Ensembl NCBI GeneCards UniProt Show fit	T cell leukemia homeobox 3
chr6_+_45328203 Show fit	3.03	ENST00000371432.7 ENST00000647337.2 ENST00000371438.5	RUNX2 Ensembl NCBI GeneCards UniProt Show fit	RUNX family transcription factor 2
chr7_+_107470050 Show fit	3.01	ENST00000304402.6	GPR22 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 22
chr2_+_161416273 Show fit	2.99	ENST00000389554.8	TBR1 Ensembl NCBI GeneCards UniProt Show fit	T-box brain transcription factor 1
chr2_+_165572329 Show fit	2.99	ENST00000342316.8	CSRNP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and serine rich nuclear protein 3
chr18_-_55422492 Show fit	2.97	ENST00000561992.5 ENST00000630712.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr16_+_7332839 Show fit	2.94	ENST00000355637.9	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr1_+_50103903 Show fit	2.91	ENST00000371827.5	ELAVL4 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr6_-_46325641 Show fit	2.88	ENST00000330430.10 ENST00000405162.2	RCAN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 2
chr3_+_1092654 Show fit	2.84	ENST00000350110.2	CNTN6 Ensembl NCBI GeneCards UniProt Show fit	contactin 6
chr11_+_123525822 Show fit	2.80	ENST00000322282.11 ENST00000529750.5	GRAMD1B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 1B
chr18_-_55423757 Show fit	2.76	ENST00000675707.1	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr21_-_30166782 Show fit	2.72	ENST00000286808.5	CLDN17 Ensembl NCBI GeneCards UniProt Show fit	claudin 17
chr16_+_7303245 Show fit	2.68	ENST00000674626.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr2_-_49973939 Show fit	2.63	ENST00000630656.1	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr2_+_172860038 Show fit	2.60	ENST00000538974.5 ENST00000540783.5	RAPGEF4 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 4
chr5_-_24644968 Show fit	2.58	ENST00000264463.8	CDH10 Ensembl NCBI GeneCards UniProt Show fit	cadherin 10
chr16_+_55656089 Show fit	2.56	ENST00000414754.7	SLC6A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 2
chr14_+_61187544 Show fit	2.56	ENST00000555185.5 ENST00000557294.5 ENST00000556778.5	PRKCH Ensembl NCBI GeneCards UniProt Show fit	protein kinase C eta
chr12_-_13095628 Show fit	2.55	ENST00000457134.6 ENST00000537302.5	GSG1 Ensembl NCBI GeneCards UniProt Show fit	germ cell associated 1
chr10_+_113126670 Show fit	2.53	ENST00000369389.6	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr16_+_7332744 Show fit	2.52	ENST00000436368.6 ENST00000311745.9 ENST00000340209.8 ENST00000620507.4	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr5_+_161848112 Show fit	2.44	ENST00000393943.10	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr14_-_91947383 Show fit	2.42	ENST00000267620.14	FBLN5 Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chr16_+_55655960 Show fit	2.40	ENST00000568943.6	SLC6A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 2
chr15_+_58138368 Show fit	2.39	ENST00000219919.9 ENST00000536493.1	AQP9 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr9_-_121050264 Show fit	2.38	ENST00000223642.3	C5 Ensembl NCBI GeneCards UniProt Show fit	complement C5
chr2_-_49974155 Show fit	2.38	ENST00000635519.1	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr5_+_162067858 Show fit	2.37	ENST00000361925.9	GABRG2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr14_-_24081928 Show fit	2.36	ENST00000396995.1	NRL Ensembl NCBI GeneCards UniProt Show fit	neural retina leucine zipper
chr4_+_73404255 Show fit	2.35	ENST00000621628.4 ENST00000621085.4 ENST00000415165.6 ENST00000295897.9 ENST00000503124.5 ENST00000509063.5 ENST00000401494.7	ALB Ensembl NCBI GeneCards UniProt Show fit	albumin
chr16_+_55656294 Show fit	2.35	ENST00000379906.6	SLC6A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 2
chr11_-_8263858 Show fit	2.32	ENST00000534484.1 ENST00000335790.8	LMO1 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 1
chr6_+_99606833 Show fit	2.32	ENST00000369215.5	PRDM13 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 13
chr10_-_101229449 Show fit	2.32	ENST00000370193.4	LBX1 Ensembl NCBI GeneCards UniProt Show fit	ladybird homeobox 1
chr9_+_79571956 Show fit	2.28	ENST00000376552.8	TLE4 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr2_-_49974182 Show fit	2.28	ENST00000412315.5 ENST00000378262.7	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr2_+_176157293 Show fit	2.24	ENST00000683222.1	HOXD3 Ensembl NCBI GeneCards UniProt Show fit	homeobox D3
chr7_-_78489900 Show fit	2.24	ENST00000636039.1	MAGI2 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_116030735 Show fit	2.23	ENST00000393485.5	TFEC Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr16_+_7510102 Show fit	2.23	ENST00000682918.1 ENST00000683326.1 ENST00000570626.2	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr18_-_55321640 Show fit	2.21	ENST00000637169.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr12_-_13095664 Show fit	2.19	ENST00000337630.10 ENST00000545699.1	GSG1 Ensembl NCBI GeneCards UniProt Show fit	germ cell associated 1
chr12_-_13095798 Show fit	2.19	ENST00000396302.7	GSG1 Ensembl NCBI GeneCards UniProt Show fit	germ cell associated 1
chrX_+_136169833 Show fit	2.18	ENST00000628032.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr2_+_66435116 Show fit	2.16	ENST00000272369.14 ENST00000560281.6	MEIS1 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 1
chr1_-_203086001 Show fit	2.16	ENST00000241651.5	MYOG Ensembl NCBI GeneCards UniProt Show fit	myogenin
chr12_-_23951020 Show fit	2.16	ENST00000441133.2 ENST00000545921.5	SOX5 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 5
chr2_-_2324642 Show fit	2.11	ENST00000650485.1 ENST00000649207.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr17_-_10469558 Show fit	2.10	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr7_+_28412511 Show fit	2.10	ENST00000357727.7	CREB5 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 5
chr5_+_36606355 Show fit	2.09	ENST00000681909.1 ENST00000513903.5 ENST00000681795.1 ENST00000680125.1 ENST00000612708.5 ENST00000680232.1 ENST00000681776.1 ENST00000681926.1 ENST00000679958.1 ENST00000265113.9 ENST00000504121.5 ENST00000512374.1 ENST00000613445.5 ENST00000679983.1	SLC1A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 3
chr16_+_55656249 Show fit	2.08	ENST00000219833.13 ENST00000574918.2	SLC6A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 2
chr12_-_102480552 Show fit	2.06	ENST00000337514.11 ENST00000307046.8	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr10_+_113125536 Show fit	2.06	ENST00000349937.7	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr17_-_10518536 Show fit	2.06	ENST00000226207.6	MYH1 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 1
chr17_-_10549694 Show fit	2.03	ENST00000622564.4	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr14_-_24081986 Show fit	2.03	ENST00000560550.1	NRL Ensembl NCBI GeneCards UniProt Show fit	neural retina leucine zipper
chr5_-_161546970 Show fit	2.02	ENST00000675303.1	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr4_+_87799546 Show fit	1.99	ENST00000226284.7	IBSP Ensembl NCBI GeneCards UniProt Show fit	integrin binding sialoprotein
chr2_-_207165923 Show fit	1.99	ENST00000309446.11	KLF7 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 7
chr12_-_102480638 Show fit	1.99	ENST00000392904.5	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr7_-_116030750 Show fit	1.98	ENST00000265440.12 ENST00000320239.11	TFEC Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chrX_+_136197020 Show fit	1.95	ENST00000370676.7	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr3_-_62374293 Show fit	1.94	ENST00000486811.5	FEZF2 Ensembl NCBI GeneCards UniProt Show fit	FEZ family zinc finger 2
chr8_-_132111159 Show fit	1.93	ENST00000673615.1 ENST00000434736.6	HHLA1 Ensembl NCBI GeneCards UniProt Show fit	HERV-H LTR-associating 1
chr5_+_162067458 Show fit	1.87	ENST00000639975.1 ENST00000639111.2 ENST00000639683.1	GABRG2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr2_+_44941695 Show fit	1.86	ENST00000260653.5	SIX3 Ensembl NCBI GeneCards UniProt Show fit	SIX homeobox 3
chr4_+_157220691 Show fit	1.86	ENST00000509417.5 ENST00000645636.1 ENST00000296526.12 ENST00000264426.14	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr14_-_53956811 Show fit	1.85	ENST00000559087.5 ENST00000245451.9	BMP4 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 4
chr5_+_162067500 Show fit	1.85	ENST00000639384.1 ENST00000640985.1 ENST00000638772.1	GABRG2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr12_-_51217671 Show fit	1.84	ENST00000333640.11 ENST00000550824.6	POU6F1 Ensembl NCBI GeneCards UniProt Show fit	POU class 6 homeobox 1
chr6_+_108166015 Show fit	1.82	ENST00000368986.9	NR2E1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group E member 1
chr2_-_49974083 Show fit	1.82	ENST00000636345.1	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr8_-_86743626 Show fit	1.80	ENST00000320005.6	CNGB3 Ensembl NCBI GeneCards UniProt Show fit	cyclic nucleotide gated channel subunit beta 3
chr5_-_60488055 Show fit	1.78	ENST00000505507.6 ENST00000515835.2 ENST00000502484.6	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr11_-_85627322 Show fit	1.76	ENST00000376104.7	DLG2 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 2
chr5_-_59586393 Show fit	1.75	ENST00000505453.1 ENST00000360047.9	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr6_-_32190170 Show fit	1.75	ENST00000375050.6	PBX2 Ensembl NCBI GeneCards UniProt Show fit	PBX homeobox 2
chr12_-_116881431 Show fit	1.74	ENST00000257572.5	HRK Ensembl NCBI GeneCards UniProt Show fit	harakiri, BCL2 interacting protein
chr4_+_95091462 Show fit	1.73	ENST00000264568.8	BMPR1B Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein receptor type 1B
chr8_-_18887018 Show fit	1.72	ENST00000523619.5	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr9_-_122227525 Show fit	1.71	ENST00000373755.6 ENST00000373754.6	LHX6 Ensembl NCBI GeneCards UniProt Show fit	LIM homeobox 6
chr18_+_57352541 Show fit	1.71	ENST00000324000.4	ST8SIA3 Ensembl NCBI GeneCards UniProt Show fit	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr1_+_204870831 Show fit	1.70	ENST00000404076.5 ENST00000539706.6	NFASC Ensembl NCBI GeneCards UniProt Show fit	neurofascin
chr17_-_48593748 Show fit	1.68	ENST00000239151.6	HOXB5 Ensembl NCBI GeneCards UniProt Show fit	homeobox B5
chr15_-_70097874 Show fit	1.68	ENST00000557997.5 ENST00000317509.12 ENST00000451782.7 ENST00000627388.2	TLE3 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 3, transcriptional corepressor
chr6_-_136525961 Show fit	1.66	ENST00000438100.6	MAP7 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 7
chr10_+_10798570 Show fit	1.65	ENST00000638035.1 ENST00000636488.1	CELF2 Ensembl NCBI GeneCards UniProt Show fit	CUGBP Elav-like family member 2
chr3_-_62373538 Show fit	1.65	ENST00000283268.8	FEZF2 Ensembl NCBI GeneCards UniProt Show fit	FEZ family zinc finger 2
chr4_+_99574812 Show fit	1.64	ENST00000422897.6 ENST00000265517.10	MTTP Ensembl NCBI GeneCards UniProt Show fit	microsomal triglyceride transfer protein
chr11_-_129192291 Show fit	1.57	ENST00000682385.1	ARHGAP32 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 32
chr7_-_25228485 Show fit	1.56	ENST00000222674.2	NPVF Ensembl NCBI GeneCards UniProt Show fit	neuropeptide VF precursor
chr2_-_181680490 Show fit	1.53	ENST00000684145.1 ENST00000295108.4 ENST00000684079.1 ENST00000683430.1	CERKL Ensembl NCBI GeneCards UniProt Show fit NEUROD1 Ensembl NCBI GeneCards UniProt Show fit	ceramide kinase like neuronal differentiation 1
chr9_-_20622479 Show fit	1.52	ENST00000380338.9	MLLT3 Ensembl NCBI GeneCards UniProt Show fit	MLLT3 super elongation complex subunit
chrX_+_136169891 Show fit	1.50	ENST00000449474.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr5_-_58999885 Show fit	1.50	ENST00000317118.12	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr3_+_4680617 Show fit	1.49	ENST00000648212.1	ITPR1 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-trisphosphate receptor type 1
chrX_+_11293411 Show fit	1.48	ENST00000348912.4 ENST00000380714.7 ENST00000380712.7	AMELX Ensembl NCBI GeneCards UniProt Show fit	amelogenin X-linked
chr16_+_8712943 Show fit	1.48	ENST00000561870.5 ENST00000396600.6	ABAT Ensembl NCBI GeneCards UniProt Show fit	4-aminobutyrate aminotransferase
chr4_-_175812746 Show fit	1.47	ENST00000393658.6	GPM6A Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6A
chr17_-_48530910 Show fit	1.47	ENST00000577092.1 ENST00000239174.7	HOXB1 Ensembl NCBI GeneCards UniProt Show fit	homeobox B1
chr3_-_114624193 Show fit	1.46	ENST00000481632.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr10_+_113553039 Show fit	1.43	ENST00000351270.4	HABP2 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan binding protein 2
chr11_-_129192198 Show fit	1.43	ENST00000310343.13	ARHGAP32 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 32
chr8_-_69833338 Show fit	1.39	ENST00000524945.5	SLCO5A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 5A1
chr9_-_70869029 Show fit	1.39	ENST00000361823.9 ENST00000377101.5 ENST00000360823.6 ENST00000377105.5	TRPM3 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily M member 3
chr3_-_54928044 Show fit	1.36	ENST00000273286.6	LRTM1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and transmembrane domains 1
chr1_-_216723437 Show fit	1.35	ENST00000459955.5 ENST00000366937.5 ENST00000391890.7	ESRRG Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr5_+_161848314 Show fit	1.35	ENST00000437025.6	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr10_+_112950586 Show fit	1.34	ENST00000355717.9 ENST00000352065.10 ENST00000369395.6 ENST00000545257.6	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr5_+_162067764 Show fit	1.33	ENST00000639213.2 ENST00000414552.6	GABRG2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr11_-_36598221 Show fit	1.32	ENST00000311485.8 ENST00000527033.5 ENST00000532616.1 ENST00000618712.4	RAG2 Ensembl NCBI GeneCards UniProt Show fit	recombination activating 2
chr9_+_2717479 Show fit	1.31	ENST00000382082.4	KCNV2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel modifier subfamily V member 2
chrX_+_9463272 Show fit	1.31	ENST00000407597.7 ENST00000380961.5 ENST00000424279.6	TBL1X Ensembl NCBI GeneCards UniProt Show fit	transducin beta like 1 X-linked
chr2_-_2331225 Show fit	1.26	ENST00000648627.1 ENST00000649663.1 ENST00000650560.1 ENST00000428368.7 ENST00000648316.1 ENST00000648665.1 ENST00000649313.1 ENST00000399161.7 ENST00000647738.2	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr6_-_22297028 Show fit	1.26	ENST00000306482.2	PRL Ensembl NCBI GeneCards UniProt Show fit	prolactin
chr16_+_86578543 Show fit	1.22	ENST00000320241.5	FOXL1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box L1
chr5_-_88785493 Show fit	1.21	ENST00000503554.4	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr11_-_84923403 Show fit	1.20	ENST00000532653.5	DLG2 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 2
chr7_-_151167692 Show fit	1.20	ENST00000297537.5	GBX1 Ensembl NCBI GeneCards UniProt Show fit	gastrulation brain homeobox 1
chr17_-_10549612 Show fit	1.20	ENST00000532183.6 ENST00000397183.6 ENST00000420805.1	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr5_-_34043205 Show fit	1.18	ENST00000382065.8 ENST00000231338.7	C1QTNF3 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 3
chr7_+_38977904 Show fit	1.18	ENST00000518318.7 ENST00000403058.6	POU6F2 Ensembl NCBI GeneCards UniProt Show fit	POU class 6 homeobox 2
chr12_-_102197827 Show fit	1.17	ENST00000329406.5	PMCH Ensembl NCBI GeneCards UniProt Show fit	pro-melanin concentrating hormone
chr18_-_34224871 Show fit	1.17	ENST00000261592.10	NOL4 Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 4
chr8_+_84705920 Show fit	1.15	ENST00000523850.5 ENST00000521376.1	RALYL Ensembl NCBI GeneCards UniProt Show fit	RALY RNA binding protein like
chr3_+_69936629 Show fit	1.15	ENST00000394348.2 ENST00000531774.1	MITF Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chr6_-_33192454 Show fit	1.15	ENST00000395194.1 ENST00000341947.7 ENST00000374708.8	COL11A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type XI alpha 2 chain
chr12_+_80716906 Show fit	1.15	ENST00000228644.4	MYF5 Ensembl NCBI GeneCards UniProt Show fit	myogenic factor 5
chr2_-_77522347 Show fit	1.13	ENST00000409093.1 ENST00000409884.6 ENST00000409088.3	LRRTM4 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat transmembrane neuronal 4
chr12_-_102480604 Show fit	1.12	ENST00000392905.7	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chrY_-_6874027 Show fit	1.09	ENST00000215479.10	AMELY Ensembl NCBI GeneCards UniProt Show fit	amelogenin Y-linked
chr2_-_55334529 Show fit	1.08	ENST00000645860.1 ENST00000642563.1 ENST00000647396.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr2_+_209579598 Show fit	1.07	ENST00000445941.5 ENST00000673860.1	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr12_+_6840800 Show fit	1.04	ENST00000541978.5 ENST00000229264.8 ENST00000435982.6	GNB3 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit beta 3
chr3_-_114758940 Show fit	1.03	ENST00000464560.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr11_+_131370478 Show fit	1.03	ENST00000374791.7 ENST00000683400.1 ENST00000436745.5	NTM Ensembl NCBI GeneCards UniProt Show fit	neurotrimin
chr2_-_2331336 Show fit	1.02	ENST00000648933.1 ENST00000644820.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr2_-_160200251 Show fit	1.00	ENST00000428609.6 ENST00000409967.6 ENST00000283249.7	ITGB6 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 6
chr1_-_53142577 Show fit	1.00	ENST00000620347.5 ENST00000611397.5	SLC1A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 7
chr18_-_3845292 Show fit	1.00	ENST00000400145.6	DLGAP1 Ensembl NCBI GeneCards UniProt Show fit	DLG associated protein 1
chr17_-_10549652 Show fit	0.98	ENST00000245503.10	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr2_+_225399684 Show fit	0.98	ENST00000636099.1	NYAP2 Ensembl NCBI GeneCards UniProt Show fit	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr13_-_27969295 Show fit	0.95	ENST00000381020.8	CDX2 Ensembl NCBI GeneCards UniProt Show fit	caudal type homeobox 2
chr1_+_50108856 Show fit	0.94	ENST00000650764.1 ENST00000494555.2 ENST00000371824.7 ENST00000371823.8 ENST00000652693.1	ELAVL4 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr1_-_217076889 Show fit	0.93	ENST00000493748.5 ENST00000463665.5	ESRRG Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr9_+_2015186 Show fit	0.92	ENST00000357248.8 ENST00000450198.6 ENST00000634287.1	SMARCA2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_216723410 Show fit	0.91	ENST00000469486.5 ENST00000481543.1 ENST00000408911.8	ESRRG Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr2_-_45009401 Show fit	0.90	ENST00000303077.7	SIX2 Ensembl NCBI GeneCards UniProt Show fit	SIX homeobox 2
chr4_-_152352800 Show fit	0.89	ENST00000393956.9	FBXW7 Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 7
chr14_+_64715677 Show fit	0.89	ENST00000634379.2	PLEKHG3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and RhoGEF domain containing G3
chr12_-_117361614 Show fit	0.89	ENST00000317775.11	NOS1 Ensembl NCBI GeneCards UniProt Show fit	nitric oxide synthase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	39.9	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
4.2	12.6	GO:0022012	subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
2.5	12.5	GO:0007403	glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
2.5	20.0	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.8	23.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.6	6.5	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
1.6	7.8	GO:0061032	cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
1.4	4.2	GO:1904580	regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
1.4	4.1	GO:0060435	bronchiole development(GO:0060435)
1.0	5.2	GO:1904073	regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.0	4.8	GO:0021764	amygdala development(GO:0021764)
0.9	4.4	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.8	9.1	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.8	2.4	GO:0019836	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.8	5.4	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.8	20.6	GO:0071420	cellular response to histamine(GO:0071420)
0.7	2.2	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7	3.4	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.6	2.6	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6	1.8	GO:1901963	regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.6	2.4	GO:1904823	canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.6	2.4	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.6	13.6	GO:0035855	megakaryocyte development(GO:0035855)
0.6	5.0	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.5	8.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4	3.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.4	2.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.4	1.2	GO:0048865	stem cell fate commitment(GO:0048865)
0.4	1.5	GO:1904448	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.4	1.5	GO:0021571	rhombomere 5 development(GO:0021571)
0.4	9.4	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.4	2.2	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.3	2.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3	1.7	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.3	1.7	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3	12.1	GO:0048665	neuron fate specification(GO:0048665)
0.3	1.3	GO:0002331	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.3	7.8	GO:0021542	dentate gyrus development(GO:0021542)
0.3	1.1	GO:0060023	soft palate development(GO:0060023)
0.3	4.2	GO:0001778	plasma membrane repair(GO:0001778)
0.3	1.1	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.3	3.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	1.7	GO:1902731	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.2	1.2	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.2	0.9	GO:1902732	condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168) positive regulation of chondrocyte proliferation(GO:1902732)
0.2	2.2	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.2	0.9	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2	0.4	GO:0003358	noradrenergic neuron development(GO:0003358)
0.2	3.9	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.2	0.8	GO:0010157	response to chlorate(GO:0010157)
0.2	3.6	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.2	0.9	GO:0014807	regulation of somitogenesis(GO:0014807)
0.2	1.7	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.2	0.8	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.2	1.1	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.2	1.7	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.2	5.7	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.2	1.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	6.5	GO:0097120	receptor localization to synapse(GO:0097120)
0.1	1.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.1	36.2	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.1	7.5	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.1	1.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	1.6	GO:0034378	chylomicron assembly(GO:0034378)
0.1	6.9	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	3.9	GO:0060612	adipose tissue development(GO:0060612)
0.1	2.5	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.1	0.6	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	1.0	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.1	0.7	GO:0070995	NADPH oxidation(GO:0070995)
0.1	2.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	5.7	GO:0032508	DNA duplex unwinding(GO:0032508)
0.1	2.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	1.8	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	2.2	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.1	1.7	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	3.0	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	7.8	GO:0070268	cornification(GO:0070268)
0.1	0.1	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.1	1.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	1.3	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	3.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	1.5	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	2.0	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	3.4	GO:0009798	axis specification(GO:0009798)
0.0	0.8	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	2.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	1.9	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.8	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	3.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	1.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.2	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	2.5	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.5	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.2	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	4.6	GO:0034605	cellular response to heat(GO:0034605)
0.0	2.8	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.3	GO:0034465	response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.0	2.1	GO:0014823	response to activity(GO:0014823)
0.0	8.5	GO:0050657	nucleic acid transport(GO:0050657) RNA transport(GO:0050658)
0.0	1.0	GO:0008038	neuron recognition(GO:0008038)
0.0	0.7	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.8	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	3.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	2.3	GO:0016571	histone methylation(GO:0016571)
0.0	1.1	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.5	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	12.5	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
1.8	23.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.8	4.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.6	5.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.6	1.9	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.5	21.3	GO:1902711	GABA-A receptor complex(GO:1902711)
0.4	1.1	GO:0005592	collagen type XI trimer(GO:0005592)
0.4	1.5	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.3	3.1	GO:0071953	elastic fiber(GO:0071953)
0.3	1.7	GO:0097454	Schwann cell microvillus(GO:0097454)
0.3	1.0	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.3	12.6	GO:0016592	mediator complex(GO:0016592)
0.3	2.4	GO:0005579	membrane attack complex(GO:0005579)
0.2	1.1	GO:1990425	ryanodine receptor complex(GO:1990425)
0.2	35.0	GO:0032993	protein-DNA complex(GO:0032993)
0.2	4.2	GO:0032982	myosin filament(GO:0032982)
0.2	2.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	7.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	17.3	GO:0042734	presynaptic membrane(GO:0042734)
0.1	1.5	GO:0005955	calcineurin complex(GO:0005955)
0.1	1.1	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	0.9	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	1.7	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	2.2	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.8	GO:0097443	sorting endosome(GO:0097443)
0.1	5.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	7.8	GO:0005882	intermediate filament(GO:0005882)
0.1	2.7	GO:0034707	chloride channel complex(GO:0034707)
0.1	8.5	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.2	GO:0016235	aggresome(GO:0016235)
0.0	0.8	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	4.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	3.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	16.6	GO:0098794	postsynapse(GO:0098794)
0.0	1.3	GO:0031904	endosome lumen(GO:0031904)
0.0	8.7	GO:0045121	membrane raft(GO:0045121)
0.0	2.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	2.1	GO:0042383	sarcolemma(GO:0042383)
0.0	1.3	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	1.3	GO:0005876	spindle microtubule(GO:0005876)
0.0	4.1	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.2	GO:0005581	collagen trimer(GO:0005581)
0.0	4.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.2	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	2.7	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	1.7	GO:0001650	fibrillar center(GO:0001650)
0.0	0.9	GO:0000794	condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	9.4	GO:0005334	norepinephrine:sodium symporter activity(GO:0005334)
1.7	36.2	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.6	27.7	GO:0003680	AT DNA binding(GO:0003680)
0.9	9.4	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8	2.4	GO:0015265	urea channel activity(GO:0015265)
0.7	12.5	GO:0070411	I-SMAD binding(GO:0070411)
0.7	3.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5	8.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.5	1.5	GO:0046848	hydroxyapatite binding(GO:0046848)
0.4	2.6	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.4	3.8	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4	9.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.4	1.9	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.4	1.5	GO:0003867	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.4	3.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.3	1.3	GO:0005148	prolactin receptor binding(GO:0005148)
0.3	1.8	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.3	4.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.3	5.7	GO:0005112	Notch binding(GO:0005112)
0.3	23.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	1.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2	8.0	GO:0008066	glutamate receptor activity(GO:0008066)
0.2	4.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	2.0	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.2	3.7	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2	0.8	GO:0097108	hedgehog family protein binding(GO:0097108)
0.2	1.5	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2	1.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.2	1.1	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2	1.8	GO:0039706	co-receptor binding(GO:0039706)
0.2	3.9	GO:0017091	AU-rich element binding(GO:0017091)
0.2	1.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	2.4	GO:0015643	toxic substance binding(GO:0015643)
0.2	6.3	GO:0000146	microfilament motor activity(GO:0000146)
0.1	7.6	GO:0030552	cAMP binding(GO:0030552)
0.1	0.8	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.4	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.1	1.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	7.5	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	1.7	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	1.9	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.6	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	0.8	GO:0005499	vitamin D binding(GO:0005499)
0.1	5.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.1	5.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	1.2	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.8	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	9.1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.9	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	2.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	5.0	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	2.5	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	1.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	4.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	1.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	1.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	2.4	GO:0008009	chemokine activity(GO:0008009)
0.0	1.4	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	2.7	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.9	GO:0002162	dystroglycan binding(GO:0002162)
0.0	2.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	6.1	GO:0005178	integrin binding(GO:0005178)
0.0	2.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	7.1	GO:0044325	ion channel binding(GO:0044325)
0.0	1.5	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	2.3	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.4	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	2.7	GO:0005254	chloride channel activity(GO:0005254)
0.0	2.9	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	1.0	GO:0030507	spectrin binding(GO:0030507)
0.0	1.6	GO:0005548	phospholipid transporter activity(GO:0005548)
0.0	2.8	GO:0003774	motor activity(GO:0003774)
0.0	1.8	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	2.5	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	3.0	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	24.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.4	12.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.3	20.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.3	36.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	13.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	2.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	2.8	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	2.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	5.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	3.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	6.6	PID NOTCH PATHWAY	Notch signaling pathway
0.1	4.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	3.6	PID BMP PATHWAY	BMP receptor signaling
0.1	3.0	PID FGF PATHWAY	FGF signaling pathway
0.0	1.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	2.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	2.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	5.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	2.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	4.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.1	PID LKB1 PATHWAY	LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	66.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.9	23.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.6	21.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.4	8.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	8.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	4.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	2.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	2.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	4.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	0.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	4.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	7.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	1.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	3.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	1.9	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.7	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	2.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	2.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	2.6	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	1.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	3.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	2.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	2.5	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	7.1	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	4.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	3.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	2.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	3.3	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis

Results for HOXA6

Z-value: 3.50

Motif logo

Transcription factors associated with HOXA6

Activity-expression correlation:

Activity profile of HOXA6 motif

Sorted Z-values of HOXA6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA6

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: