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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXB8

Z-value: 2.18

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
HOXB8
ENSG00000120068.7 HOXB8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg38_v1_chr17_-_48613468_486135220.194.6e-03Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_107824294 15.41 ENST00000369020.8
ENST00000369022.6
SCML4
Scm polycomb group protein like 4
chr8_+_81280527 6.79 ENST00000297258.11
FABP5
fatty acid binding protein 5
chr19_-_10587219 5.82 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
AP1M2
adaptor related protein complex 1 subunit mu 2
chr8_-_80171106 5.78 ENST00000519303.6
TPD52
tumor protein D52
chr14_-_106658251 5.36 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr3_-_111595339 5.36 ENST00000317012.5
ZBED2
zinc finger BED-type containing 2
chr19_-_20565746 4.82 ENST00000594419.1
ZNF737
zinc finger protein 737
chr8_+_133113483 4.48 ENST00000521107.1
TG
thyroglobulin
chr13_+_73054969 4.41 ENST00000539231.5
KLF5
Kruppel like factor 5
chr5_-_126595237 4.33 ENST00000637206.1
ENST00000553117.5
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr19_-_20565769 4.29 ENST00000427401.9
ZNF737
zinc finger protein 737
chr10_+_5446601 4.18 ENST00000449083.5
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr5_+_126423363 3.98 ENST00000285689.8
GRAMD2B
GRAM domain containing 2B
chr8_+_97775775 3.88 ENST00000521545.7
LAPTM4B
lysosomal protein transmembrane 4 beta
chr3_+_148827800 3.86 ENST00000282957.9
ENST00000468341.1
CPB1
carboxypeptidase B1
chr8_+_97887903 3.83 ENST00000520016.5
MATN2
matrilin 2
chr2_-_55917699 3.74 ENST00000634374.1
EFEMP1
EGF containing fibulin extracellular matrix protein 1
chr4_+_25160631 3.71 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS-AS1
PI4K2B
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr11_+_2384603 3.67 ENST00000527343.5
ENST00000464784.6
CD81
CD81 molecule
chr4_-_71784046 3.66 ENST00000513476.5
ENST00000273951.13
GC
GC vitamin D binding protein
chr4_-_70666492 3.52 ENST00000254801.9
ENST00000391614.7
JCHAIN
joining chain of multimeric IgA and IgM
chr11_-_102530738 3.44 ENST00000260227.5
MMP7
matrix metallopeptidase 7
chr4_+_68815991 3.39 ENST00000265403.12
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase family 2 member B10
chr1_+_236394268 3.33 ENST00000334232.9
EDARADD
EDAR associated death domain
chr8_+_127735597 3.29 ENST00000651626.1
MYC
MYC proto-oncogene, bHLH transcription factor
chr9_+_128149447 3.23 ENST00000277480.7
ENST00000372998.1
LCN2
lipocalin 2
chr1_+_103617427 3.22 ENST00000423678.2
ENST00000414303.7
AMY2A
amylase alpha 2A
chr22_+_22822658 3.17 ENST00000620395.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr12_+_20815672 3.16 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
SLCO1B3
SLCO1B3-SLCO1B7
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr5_-_42825884 3.08 ENST00000506577.5
SELENOP
selenoprotein P
chr10_+_46375645 3.08 ENST00000622769.4
ANXA8L1
annexin A8 like 1
chr16_-_20327426 3.05 ENST00000575582.5
ENST00000341642.9
ENST00000381362.8
ENST00000572347.5
ENST00000572478.5
ENST00000302555.10
GP2
glycoprotein 2
chr13_-_48037934 3.03 ENST00000646804.1
ENST00000643246.1
SUCLA2
succinate-CoA ligase ADP-forming subunit beta
chr11_-_13495984 3.03 ENST00000282091.6
PTH
parathyroid hormone
chr12_+_25052634 3.03 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr10_+_46375619 3.02 ENST00000584982.7
ENST00000613703.4
ANXA8L1
annexin A8 like 1
chr11_-_13496018 2.93 ENST00000529816.1
PTH
parathyroid hormone
chr14_-_54441325 2.92 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr5_+_126423176 2.90 ENST00000542322.5
ENST00000544396.5
GRAMD2B
GRAM domain containing 2B
chr5_+_160421847 2.86 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1
PTTG1 regulator of sister chromatid separation, securin
chr10_+_46375721 2.85 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
ENSG00000285402.1
ANXA8L1
novel transcript
annexin A8 like 1
chr3_-_15440560 2.85 ENST00000595627.5
ENST00000597949.1
ENST00000494875.3
ENST00000595975.1
ENST00000598878.1
EAF1-AS1
METTL6
EAF1 antisense RNA 1
methyltransferase like 6
chr4_+_69096494 2.84 ENST00000508661.5
ENST00000622664.1
UGT2B7
UDP glucuronosyltransferase family 2 member B7
chr11_+_72192126 2.84 ENST00000393676.5
FOLR1
folate receptor alpha
chr4_+_69096467 2.82 ENST00000305231.12
UGT2B7
UDP glucuronosyltransferase family 2 member B7
chr6_-_99568713 2.78 ENST00000520371.5
CCNC
cyclin C
chr5_-_179617581 2.78 ENST00000523449.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr5_+_126423122 2.75 ENST00000515200.5
GRAMD2B
GRAM domain containing 2B
chr2_+_186590022 2.75 ENST00000261023.8
ENST00000374907.7
ITGAV
integrin subunit alpha V
chr4_-_69961007 2.65 ENST00000353151.3
CSN2
casein beta
chr5_-_123036664 2.62 ENST00000306442.5
PPIC
peptidylprolyl isomerase C
chr12_+_25052732 2.61 ENST00000547044.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr4_+_69280472 2.59 ENST00000335568.10
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase family 2 member B28
chr4_+_73409340 2.59 ENST00000511370.1
ALB
albumin
chr11_+_134331874 2.59 ENST00000339772.9
ENST00000535456.7
GLB1L2
galactosidase beta 1 like 2
chr3_+_148791058 2.58 ENST00000491148.5
CPB1
carboxypeptidase B1
chr22_-_30246739 2.56 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr21_-_42315336 2.56 ENST00000398431.2
ENST00000518498.3
TFF3
trefoil factor 3
chr14_-_67412112 2.55 ENST00000216446.9
PLEK2
pleckstrin 2
chr17_-_66229380 2.53 ENST00000205948.11
APOH
apolipoprotein H
chr2_+_1414382 2.52 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
TPO
thyroid peroxidase
chr1_+_19596960 2.50 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
MICOS10
NBL1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr9_-_21995301 2.50 ENST00000498628.6
CDKN2A
cyclin dependent kinase inhibitor 2A
chr21_-_10649835 2.40 ENST00000622028.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_+_191276885 2.39 ENST00000392316.5
MYO1B
myosin IB
chr2_+_233671879 2.39 ENST00000354728.5
UGT1A9
UDP glucuronosyltransferase family 1 member A9
chr11_+_102112445 2.39 ENST00000524575.5
YAP1
Yes1 associated transcriptional regulator
chr15_-_21718245 2.38 ENST00000630556.1
ENSG00000281179.1
novel gene identicle to IGHV1OR15-1
chr1_-_200620729 2.35 ENST00000367350.5
KIF14
kinesin family member 14
chr16_-_20327801 2.34 ENST00000381360.9
GP2
glycoprotein 2
chr18_+_657637 2.33 ENST00000323274.15
TYMS
thymidylate synthetase
chr9_+_33795551 2.32 ENST00000379405.4
PRSS3
serine protease 3
chr12_-_91111460 2.32 ENST00000266718.5
LUM
lumican
chr19_-_17377334 2.29 ENST00000252590.9
ENST00000599426.1
PLVAP
plasmalemma vesicle associated protein
chr2_+_89884740 2.29 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr1_-_94925759 2.28 ENST00000415017.1
ENST00000545882.5
CNN3
calponin 3
chr4_-_69214743 2.28 ENST00000446444.2
UGT2B11
UDP glucuronosyltransferase family 2 member B11
chr14_-_106593319 2.26 ENST00000390627.3
IGHV3-53
immunoglobulin heavy variable 3-53
chr4_+_168497066 2.23 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chr5_+_178859924 2.21 ENST00000322434.8
ZNF354B
zinc finger protein 354B
chr12_-_54259531 2.18 ENST00000550411.5
ENST00000439541.6
CBX5
chromobox 5
chr8_+_30387064 2.16 ENST00000523115.5
ENST00000519647.5
RBPMS
RNA binding protein, mRNA processing factor
chr10_-_46046264 2.15 ENST00000581478.5
ENST00000582163.3
MSMB
microseminoprotein beta
chr2_+_1484663 2.14 ENST00000446278.5
ENST00000469607.3
TPO
thyroid peroxidase
chr4_+_168497044 2.12 ENST00000505667.6
PALLD
palladin, cytoskeletal associated protein
chrX_+_120604199 2.12 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chr8_-_47960126 2.11 ENST00000314191.7
ENST00000338368.7
PRKDC
protein kinase, DNA-activated, catalytic subunit
chr13_-_106568107 2.11 ENST00000400198.8
ARGLU1
arginine and glutamate rich 1
chr2_+_176107272 2.11 ENST00000249504.7
HOXD11
homeobox D11
chr17_+_47651061 2.09 ENST00000540627.5
KPNB1
karyopherin subunit beta 1
chr15_+_41286011 2.09 ENST00000661438.1
ENSG00000285920.2
novel protein
chr1_+_103750406 2.09 ENST00000370079.3
AMY1C
amylase alpha 1C
chr7_+_16661182 2.07 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
BZW2
basic leucine zipper and W2 domains 2
chr5_+_126360113 2.06 ENST00000513040.5
GRAMD2B
GRAM domain containing 2B
chr10_+_60778331 2.05 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
CDK1
cyclin dependent kinase 1
chr20_+_36214373 2.05 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr11_-_33717409 2.02 ENST00000651485.1
CD59
CD59 molecule (CD59 blood group)
chr18_+_3252208 2.01 ENST00000578562.6
MYL12A
myosin light chain 12A
chr18_+_7754959 1.99 ENST00000400053.8
PTPRM
protein tyrosine phosphatase receptor type M
chr1_-_103696209 1.99 ENST00000330330.10
AMY1B
amylase alpha 1B
chr2_+_90038848 1.97 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr13_+_29428709 1.97 ENST00000542829.1
MTUS2
microtubule associated scaffold protein 2
chr10_+_60778490 1.95 ENST00000448257.6
ENST00000614696.4
CDK1
cyclin dependent kinase 1
chr11_-_14499803 1.95 ENST00000439561.7
ENST00000534234.5
COPB1
COPI coat complex subunit beta 1
chr6_-_131000722 1.94 ENST00000528282.5
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr1_+_53894181 1.92 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
DIO1
iodothyronine deiodinase 1
chr2_+_233729042 1.92 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chr11_-_14499833 1.91 ENST00000249923.7
ENST00000529866.5
COPB1
COPI coat complex subunit beta 1
chr19_+_52429181 1.91 ENST00000301085.8
ZNF534
zinc finger protein 534
chr8_-_90082871 1.89 ENST00000265431.7
CALB1
calbindin 1
chr6_+_36243203 1.87 ENST00000312917.9
ENST00000388715.7
PNPLA1
patatin like phospholipase domain containing 1
chr3_-_38794042 1.86 ENST00000643924.1
SCN10A
sodium voltage-gated channel alpha subunit 10
chr16_-_70289480 1.85 ENST00000261772.13
ENST00000675953.1
ENST00000675691.1
ENST00000675133.1
ENST00000674512.1
ENST00000675045.1
ENST00000675853.1
ENST00000565361.3
ENST00000674963.1
ENST00000674691.1
AARS1
alanyl-tRNA synthetase 1
chr8_+_103880412 1.85 ENST00000436393.6
RIMS2
regulating synaptic membrane exocytosis 2
chr8_+_22565655 1.82 ENST00000523965.5
SORBS3
sorbin and SH3 domain containing 3
chr6_+_29461440 1.82 ENST00000396792.2
OR2H1
olfactory receptor family 2 subfamily H member 1
chr14_-_106470788 1.81 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr4_+_74365136 1.80 ENST00000244869.3
EREG
epiregulin
chr15_+_84235773 1.80 ENST00000510439.7
ENST00000422563.6
GOLGA6L4
golgin A6 family like 4
chr9_-_114074969 1.79 ENST00000466610.6
AMBP
alpha-1-microglobulin/bikunin precursor
chr20_-_56392131 1.79 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
AURKA
aurora kinase A
chr7_-_32490361 1.78 ENST00000410044.5
ENST00000450169.7
ENST00000409987.5
ENST00000409782.5
LSM5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr18_+_31591869 1.78 ENST00000237014.8
TTR
transthyretin
chr11_-_63608542 1.78 ENST00000540943.1
PLAAT3
phospholipase A and acyltransferase 3
chr2_-_89010515 1.77 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr18_-_14132423 1.76 ENST00000589498.5
ENST00000590202.3
ZNF519
zinc finger protein 519
chr12_+_64404338 1.76 ENST00000332707.10
XPOT
exportin for tRNA
chr2_-_264024 1.74 ENST00000403712.6
ENST00000356150.10
ENST00000626873.2
ENST00000405430.5
SH3YL1
SH3 and SYLF domain containing 1
chr10_+_116545907 1.73 ENST00000369221.2
PNLIP
pancreatic lipase
chr14_+_61762405 1.73 ENST00000216294.5
SNAPC1
small nuclear RNA activating complex polypeptide 1
chr3_+_105366877 1.73 ENST00000306107.9
ALCAM
activated leukocyte cell adhesion molecule
chr12_+_25052512 1.73 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr14_+_19743571 1.73 ENST00000642117.2
OR4Q3
olfactory receptor family 4 subfamily Q member 3
chr12_-_27971970 1.72 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr15_-_22160868 1.72 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr6_-_138218491 1.71 ENST00000527246.3
PBOV1
prostate and breast cancer overexpressed 1
chr4_+_25655822 1.70 ENST00000504570.5
ENST00000382051.8
SLC34A2
solute carrier family 34 member 2
chr4_+_108004482 1.66 ENST00000626637.2
HADH
hydroxyacyl-CoA dehydrogenase
chr19_-_14835252 1.65 ENST00000641666.1
ENST00000642030.1
ENST00000642000.1
OR7C1
olfactory receptor family 7 subfamily C member 1
chr1_+_13416351 1.65 ENST00000602960.1
PRAMEF20
PRAME family member 20
chr2_+_233691607 1.65 ENST00000373424.5
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chr1_-_149812359 1.65 ENST00000369167.2
ENST00000545683.1
H2BC18
H2B clustered histone 18
chr1_+_101237009 1.64 ENST00000305352.7
S1PR1
sphingosine-1-phosphate receptor 1
chr19_-_49451793 1.64 ENST00000262265.10
PIH1D1
PIH1 domain containing 1
chr5_-_179618032 1.64 ENST00000519033.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr3_+_149474688 1.64 ENST00000305354.5
ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr12_-_11269805 1.63 ENST00000538488.2
PRB3
proline rich protein BstNI subfamily 3
chr6_+_121435595 1.62 ENST00000649003.1
ENST00000282561.4
GJA1
gap junction protein alpha 1
chr2_+_90082635 1.62 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr3_+_41200104 1.62 ENST00000643297.1
ENST00000450969.6
CTNNB1
catenin beta 1
chr3_+_105367212 1.61 ENST00000472644.6
ALCAM
activated leukocyte cell adhesion molecule
chr2_+_206159884 1.61 ENST00000392222.7
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr2_+_33436304 1.60 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr8_+_103298433 1.60 ENST00000522566.5
FZD6
frizzled class receptor 6
chr12_+_21372899 1.59 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr11_+_57597563 1.59 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
SERPING1
serpin family G member 1
chr2_+_206159580 1.58 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr1_+_220094086 1.58 ENST00000366922.3
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr19_+_32581410 1.58 ENST00000586035.1
PDCD5
programmed cell death 5
chr20_+_58389197 1.58 ENST00000475243.6
ENST00000395802.7
VAPB
VAMP associated protein B and C
chr10_+_122560751 1.58 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr5_-_126595185 1.57 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr14_-_106211453 1.56 ENST00000390606.3
IGHV3-20
immunoglobulin heavy variable 3-20
chr2_+_233636445 1.52 ENST00000344644.9
UGT1A10
UDP glucuronosyltransferase family 1 member A10
chr6_+_57172290 1.52 ENST00000370693.5
BAG2
BAG cochaperone 2
chr1_-_53945584 1.50 ENST00000371377.3
HSPB11
heat shock protein family B (small) member 11
chr5_-_134367144 1.50 ENST00000265334.9
CDKL3
cyclin dependent kinase like 3
chr22_-_28800042 1.49 ENST00000405219.7
XBP1
X-box binding protein 1
chr20_-_50958520 1.49 ENST00000371588.10
ENST00000371584.9
ENST00000413082.1
ENST00000371582.8
DPM1
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr17_-_8383164 1.49 ENST00000584164.6
ENST00000582556.5
ENST00000648839.1
ENST00000578812.5
ENST00000583011.6
RPL26
ribosomal protein L26
chr1_-_53945567 1.48 ENST00000371378.6
HSPB11
heat shock protein family B (small) member 11
chr11_+_118077067 1.47 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
TMPRSS4
transmembrane serine protease 4
chr15_-_82349437 1.47 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
GOLGA6L10
golgin A6 family like 10
chr2_-_89117844 1.47 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr6_-_150025520 1.46 ENST00000367341.6
ENST00000286380.2
RAET1L
retinoic acid early transcript 1L
chr10_+_92593112 1.46 ENST00000260731.5
KIF11
kinesin family member 11
chr14_-_105987068 1.44 ENST00000390594.3
IGHV1-2
immunoglobulin heavy variable 1-2
chr11_+_118077009 1.44 ENST00000616579.4
ENST00000534111.5
TMPRSS4
transmembrane serine protease 4
chr10_+_122560679 1.44 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr19_+_20776292 1.44 ENST00000360204.5
ENST00000344519.10
ENST00000594534.5
ZNF66
zinc finger protein 66
chr12_+_26195313 1.43 ENST00000422622.3
SSPN
sarcospan
chr11_+_844406 1.42 ENST00000397404.5
TSPAN4
tetraspanin 4
chrX_+_120604084 1.41 ENST00000371317.10
MCTS1
MCTS1 re-initiation and release factor
chr16_-_10559135 1.41 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr14_-_74493275 1.41 ENST00000541064.5
NPC2
NPC intracellular cholesterol transporter 2
chr14_-_106005574 1.40 ENST00000390595.3
IGHV1-3
immunoglobulin heavy variable 1-3
chr1_+_103749898 1.39 ENST00000622339.5
AMY1C
amylase alpha 1C
chr15_-_52295792 1.39 ENST00000261839.12
MYO5C
myosin VC
chr12_-_27972725 1.38 ENST00000545234.6
PTHLH
parathyroid hormone like hormone
chr14_-_73950393 1.38 ENST00000651776.1
FAM161B
FAM161 centrosomal protein B
chr21_-_29061351 1.37 ENST00000432178.5
CCT8
chaperonin containing TCP1 subunit 8
chr2_+_43774033 1.37 ENST00000260605.12
ENST00000406852.7
ENST00000398823.6
ENST00000605786.5
DYNC2LI1
dynein cytoplasmic 2 light intermediate chain 1
chr4_+_40197023 1.37 ENST00000381799.10
RHOH
ras homolog family member H
chr22_+_22747383 1.36 ENST00000390311.3
IGLV3-16
immunoglobulin lambda variable 3-16
chr2_-_150487658 1.35 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
RND3
Rho family GTPase 3
chr1_+_165895583 1.35 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr22_+_44752552 1.35 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
ARHGAP8
Rho GTPase activating protein 8
chr14_-_106025628 1.35 ENST00000631943.1
IGHV7-4-1
immunoglobulin heavy variable 7-4-1
chr4_-_154612635 1.33 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
FGG
fibrinogen gamma chain
chr14_-_49620594 1.32 ENST00000298289.7
RPL36AL
ribosomal protein L36a like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.5 6.0 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.4 4.1 GO:1903487 regulation of lactation(GO:1903487)
1.1 4.4 GO:0002188 translation reinitiation(GO:0002188)
1.0 3.0 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.9 2.8 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.9 2.8 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.9 2.8 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.9 2.6 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.9 2.6 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.8 10.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.8 3.3 GO:0072185 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.7 3.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.7 6.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.6 3.2 GO:0015688 response to mycotoxin(GO:0010046) iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6 2.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.6 3.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.6 2.5 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.6 1.8 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.6 2.3 GO:0019860 uracil metabolic process(GO:0019860)
0.6 4.5 GO:0015705 iodide transport(GO:0015705)
0.6 4.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.5 1.6 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.5 1.6 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.5 1.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.5 2.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.5 4.0 GO:0090166 regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
0.5 3.2 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.5 1.4 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.4 1.8 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.4 3.8 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.4 2.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.4 1.7 GO:0021569 rhombomere 3 development(GO:0021569)
0.4 1.6 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.4 1.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.4 2.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.4 3.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 4.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 2.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.4 2.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.3 3.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 3.5 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.3 4.2 GO:0051451 myoblast migration(GO:0051451)
0.3 1.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 7.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.3 1.3 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.3 1.0 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.3 1.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.3 1.6 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.3 1.0 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.3 1.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 1.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.3 1.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3 2.0 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 2.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.3 2.8 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 0.8 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.3 1.6 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.3 1.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.7 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.5 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.2 1.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 1.7 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.7 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.2 1.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 0.7 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 1.9 GO:0072221 metanephric part of ureteric bud development(GO:0035502) distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.2 4.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 2.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 0.6 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 1.9 GO:0051026 chiasma assembly(GO:0051026)
0.2 1.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.2 28.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.6 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.7 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 2.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2 2.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.7 GO:0072683 T cell extravasation(GO:0072683)
0.2 2.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 1.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 1.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 5.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.2 3.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 1.8 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 1.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 7.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 2.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 2.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 0.8 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 0.2 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2 1.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 3.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.9 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 2.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 1.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 1.4 GO:0003093 regulation of glomerular filtration(GO:0003093) caveola assembly(GO:0070836)
0.1 1.2 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.1 2.0 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.9 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.9 GO:0046985 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.4 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 3.4 GO:0044849 estrous cycle(GO:0044849)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 1.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 5.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 4.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.6 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 1.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.5 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) ammonia assimilation cycle(GO:0019676) regulation of urea metabolic process(GO:0034255) bile acid signaling pathway(GO:0038183) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.9 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.1 1.2 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.1 2.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.6 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 2.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.8 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 2.0 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.1 1.4 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.9 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.8 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.9 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 0.7 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 1.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.2 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 1.3 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.3 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 0.9 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 1.8 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.5 GO:0006382 adenosine to inosine editing(GO:0006382) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.1 0.2 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 3.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.7 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.2 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 3.0 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.1 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.9 GO:0007512 adult heart development(GO:0007512)
0.1 6.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 3.8 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.3 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 1.3 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 0.8 GO:0006265 DNA topological change(GO:0006265)
0.1 0.3 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.1 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 1.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0046618 drug export(GO:0046618)
0.1 3.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.6 GO:0002385 mucosal immune response(GO:0002385)
0.1 0.9 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.2 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 1.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 2.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.3 GO:0050955 thermoception(GO:0050955)
0.1 0.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 1.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 6.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.8 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 2.6 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.2 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 4.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.3 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0048535 lymph node development(GO:0048535)
0.0 1.0 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 3.8 GO:0006414 translational elongation(GO:0006414)
0.0 3.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.6 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 3.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 2.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.6 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.9 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.7 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.3 GO:0014904 myotube cell development(GO:0014904)
0.0 0.0 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.4 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 1.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 1.4 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.8 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.6 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.0 GO:0015819 lysine transport(GO:0015819) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transport(GO:1902022) L-lysine import into cell(GO:1903410)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.2 3.5 GO:0071754 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.0 4.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.8 2.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.5 1.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 2.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4 4.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 2.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 1.4 GO:0000811 GINS complex(GO:0000811)
0.3 1.0 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.3 3.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 13.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 5.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 1.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.3 1.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 2.5 GO:0071439 clathrin complex(GO:0071439)
0.2 1.2 GO:0097149 centralspindlin complex(GO:0097149)
0.2 1.8 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 16.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.0 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 1.8 GO:0032133 chromosome passenger complex(GO:0032133) meiotic spindle(GO:0072687)
0.2 4.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 3.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 2.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.2 1.1 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.2 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 0.9 GO:0034709 methylosome(GO:0034709)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 7.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 3.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.2 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.9 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.7 GO:0031298 replication fork protection complex(GO:0031298)
0.1 7.8 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 1.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 2.4 GO:0051233 spindle midzone(GO:0051233)
0.1 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 15.1 GO:0072562 blood microparticle(GO:0072562)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.1 6.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 1.1 GO:0000800 lateral element(GO:0000800)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 7.9 GO:0016459 myosin complex(GO:0016459)
0.1 1.9 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.8 GO:0016592 mediator complex(GO:0016592)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 2.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 20.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.2 GO:0000322 storage vacuole(GO:0000322)
0.1 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 5.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 57.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.9 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 8.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 3.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0005840 ribosome(GO:0005840)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 8.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 14.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0035375 zymogen binding(GO:0035375)
1.2 3.7 GO:1902271 D3 vitamins binding(GO:1902271)
1.1 3.2 GO:0004556 alpha-amylase activity(GO:0004556)
1.1 5.3 GO:0019862 IgA binding(GO:0019862)
0.9 3.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.9 4.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.9 3.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 3.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 3.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.7 2.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.6 3.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6 22.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 2.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 1.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 1.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.5 1.9 GO:0005499 vitamin D binding(GO:0005499)
0.4 2.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 3.1 GO:0008430 selenium binding(GO:0008430)
0.4 1.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 2.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.4 1.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.4 2.5 GO:0004849 uridine kinase activity(GO:0004849)
0.3 1.6 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 1.0 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.3 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 2.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 6.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 2.5 GO:0016015 morphogen activity(GO:0016015)
0.3 6.0 GO:0048018 receptor agonist activity(GO:0048018)
0.3 1.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 1.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 5.8 GO:0035173 histone kinase activity(GO:0035173)
0.2 7.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 2.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 3.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 1.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 13.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 4.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 5.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 0.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.6 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 0.8 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.2 1.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 1.9 GO:0042731 PH domain binding(GO:0042731)
0.2 1.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321) phosphate ion binding(GO:0042301)
0.2 3.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 2.6 GO:0015643 toxic substance binding(GO:0015643)
0.2 4.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.5 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 1.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 4.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 4.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.5 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.2 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 1.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 2.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.3 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 2.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 4.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.8 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.6 GO:0046625 sphingolipid binding(GO:0046625)
0.1 1.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 3.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.4 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 6.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.0 GO:0019863 IgE binding(GO:0019863)
0.1 3.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 20.4 GO:0003823 antigen binding(GO:0003823)
0.1 1.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 3.9 GO:0000049 tRNA binding(GO:0000049)
0.1 0.5 GO:0038181 bile acid receptor activity(GO:0038181) chenodeoxycholic acid binding(GO:1902122)
0.1 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.6 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.4 GO:0035276 ethanol binding(GO:0035276)
0.1 1.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 2.7 GO:0017166 vinculin binding(GO:0017166)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.5 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 5.2 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 10.6 GO:0005179 hormone activity(GO:0005179)
0.1 0.6 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 5.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.1 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 0.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 6.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 4.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.8 GO:1900750 oligopeptide binding(GO:1900750)
0.1 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 2.0 GO:0001848 complement binding(GO:0001848)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 7.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) H3K27me3 modified histone binding(GO:0061628)
0.1 0.4 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 2.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.9 GO:0050699 WW domain binding(GO:0050699)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.1 GO:0032934 sterol binding(GO:0032934)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 3.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 4.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.5 GO:0003774 motor activity(GO:0003774)
0.0 2.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.0 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.3 GO:0008527 taste receptor activity(GO:0008527) bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 6.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 2.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 5.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 5.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 16.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 4.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.2 PID E2F PATHWAY E2F transcription factor network
0.1 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 9.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 5.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 21.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.6 7.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 7.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 6.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.4 7.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 3.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 4.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 5.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 2.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 3.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 5.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 3.5 REACTOME KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 3.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 5.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.2 REACTOME DEFENSINS Genes involved in Defensins
0.1 12.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 6.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 3.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 3.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 3.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 8.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 6.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.9 REACTOME TRANSLATION Genes involved in Translation
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 2.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives