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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXC10_HOXD13

Z-value: 4.60

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Transcription factors associated with HOXC10_HOXD13

Gene Symbol Gene ID Gene Info
ENSG00000180818.5 HOXC10
ENSG00000128714.6 HOXD13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD13hg38_v1_chr2_+_176092715_1760927290.235.8e-04Click!
HOXC10hg38_v1_chr12_+_53985138_53985183-0.127.3e-02Click!

Activity profile of HOXC10_HOXD13 motif

Sorted Z-values of HOXC10_HOXD13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC10_HOXD13

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_195583931 34.31 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr18_-_77017042 33.81 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
myelin basic protein
chr12_-_91146195 26.49 ENST00000548218.1
decorin
chr2_-_215436061 26.32 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr11_+_118530990 22.05 ENST00000411589.6
ENST00000359862.8
ENST00000442938.6
transmembrane protein 25
chr5_-_42825884 21.31 ENST00000506577.5
selenoprotein P
chr5_+_36608146 19.31 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr12_-_14885845 17.47 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr4_-_87529460 17.46 ENST00000418378.5
SPARC like 1
chr4_-_173399102 16.71 ENST00000296506.8
stimulator of chondrogenesis 1
chr6_+_42879610 16.11 ENST00000493763.7
ENST00000304734.9
ribosomal protein L7 like 1
chr3_+_101827982 14.65 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr1_+_89995102 14.49 ENST00000340281.9
ENST00000361911.9
ENST00000370447.3
zinc finger protein 326
chr2_-_135530561 14.27 ENST00000536680.5
ENST00000401392.5
zinc finger RANBP2-type containing 3
chr12_-_91179472 13.20 ENST00000550099.5
ENST00000546391.5
decorin
chr12_-_91179355 12.76 ENST00000550563.5
ENST00000546370.5
decorin
chr12_-_91182652 12.18 ENST00000552145.5
ENST00000546745.5
decorin
chr11_-_132943092 11.82 ENST00000612177.4
ENST00000541867.5
opioid binding protein/cell adhesion molecule like
chr7_-_137343752 11.63 ENST00000393083.2
pleiotrophin
chr12_-_91182784 11.58 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr14_-_21025000 11.53 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr18_-_55402187 11.07 ENST00000630268.2
ENST00000570177.6
transcription factor 4
chr6_+_29301701 11.05 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr3_-_123620571 10.93 ENST00000583087.5
myosin light chain kinase
chrM_+_4467 10.90 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr4_+_113292838 10.61 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr19_-_10309783 10.51 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr18_-_55321640 10.14 ENST00000637169.2
transcription factor 4
chr3_-_123620496 10.12 ENST00000578202.1
myosin light chain kinase
chr5_+_36596583 9.99 ENST00000680318.1
solute carrier family 1 member 3
chr7_+_134779625 9.94 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr18_-_55321986 9.66 ENST00000570287.6
transcription factor 4
chr18_-_5396265 9.55 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr12_-_91111460 9.51 ENST00000266718.5
lumican
chrX_-_104156976 9.40 ENST00000594199.3
solute carrier family 25 member 53
chr1_+_50109817 9.34 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAV like RNA binding protein 4
chr3_-_58627567 9.24 ENST00000649301.1
family with sequence similarity 107 member A
chr7_+_134779663 9.22 ENST00000361901.6
caldesmon 1
chr7_+_134866831 9.05 ENST00000435928.1
caldesmon 1
chr3_-_58577367 8.64 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr15_+_24856551 8.54 ENST00000400097.5
small nuclear ribonucleoprotein polypeptide N
chr3_+_189789672 8.44 ENST00000434928.5
tumor protein p63
chr3_-_138329839 8.24 ENST00000333911.9
ENST00000383180.6
NME/NM23 family member 9
chr21_+_34364003 7.96 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr11_-_132943671 7.88 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr18_-_55586092 7.87 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr2_-_189179754 7.79 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr3_-_58577648 7.73 ENST00000394481.5
family with sequence similarity 107 member A
chr16_+_22490337 7.73 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chr1_-_163321704 7.64 ENST00000528019.5
ENST00000427213.5
ENST00000528689.5
ENST00000439699.1
ENST00000526176.1
ENST00000449680.5
ENST00000429865.5
ENST00000618415.4
regulator of G protein signaling 5
regulator of G protein signaling 5
chr1_+_50105666 7.62 ENST00000651347.1
ELAV like RNA binding protein 4
chr9_+_98943705 7.54 ENST00000610452.1
collagen type XV alpha 1 chain
chr1_+_50109620 7.49 ENST00000371819.1
ELAV like RNA binding protein 4
chr1_-_9069608 7.40 ENST00000377424.9
solute carrier family 2 member 5
chr4_-_48016631 7.26 ENST00000513178.2
ENST00000514170.7
cyclic nucleotide gated channel subunit alpha 1
chr2_-_50347789 7.21 ENST00000628364.2
neurexin 1
chrX_+_103585478 7.14 ENST00000468024.5
ENST00000415568.2
ENST00000472484.6
ENST00000613326.4
ENST00000490644.5
ENST00000459722.1
ENST00000472745.1
ENST00000494801.5
ENST00000434216.2
transcription elongation factor A like 4
chr12_-_124567464 7.11 ENST00000458234.5
nuclear receptor corepressor 2
chr4_+_70383123 7.02 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr12_-_52321395 6.99 ENST00000293670.3
keratin 83
chr9_-_92878018 6.95 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr18_-_55585773 6.94 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr12_+_78863962 6.81 ENST00000393240.7
synaptotagmin 1
chr2_+_200440649 6.66 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr17_-_31297231 6.60 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr2_-_237414157 6.50 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
collagen type VI alpha 3 chain
chr1_+_152985231 6.47 ENST00000368762.1
small proline rich protein 1A
chr3_-_187745460 6.42 ENST00000406870.7
BCL6 transcription repressor
chr17_-_48613468 6.30 ENST00000498634.2
homeobox B8
chr19_+_35143237 6.24 ENST00000586063.5
ENST00000270310.7
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr4_+_113292925 6.11 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr1_+_50109788 6.07 ENST00000651258.1
ELAV like RNA binding protein 4
chr4_+_48016764 6.05 ENST00000295461.10
NIPA like domain containing 1
chr21_-_26845402 6.04 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr14_-_21023954 5.90 ENST00000554094.5
NDRG family member 2
chr5_-_108367860 5.86 ENST00000496714.2
F-box and leucine rich repeat protein 17
chr11_+_101914997 5.85 ENST00000263468.13
centrosomal protein 126
chr2_+_67397297 5.80 ENST00000644028.1
ENST00000272342.6
ETAA1 activator of ATR kinase
chr18_-_55322215 5.74 ENST00000457482.7
transcription factor 4
chr21_-_26843063 5.64 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr12_-_53220229 5.56 ENST00000338561.9
retinoic acid receptor gamma
chr1_+_209686173 5.56 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr13_-_32538683 5.53 ENST00000674456.1
ENST00000504114.5
NEDD4 binding protein 2 like 2
chr2_+_165572329 5.52 ENST00000342316.8
cysteine and serine rich nuclear protein 3
chr4_+_71062642 5.46 ENST00000649996.1
solute carrier family 4 member 4
chr11_-_6006946 5.35 ENST00000641156.1
ENST00000641835.1
olfactory receptor family 56 subfamily A member 4
chr5_-_131635030 5.31 ENST00000308008.10
ENST00000296859.10
ENST00000627212.2
ENST00000507093.5
ENST00000509018.6
ENST00000510071.5
Rap guanine nucleotide exchange factor 6
chr3_+_121567924 5.31 ENST00000334384.5
arginine-fifty homeobox
chr17_-_58544315 5.31 ENST00000671766.1
ENST00000672673.2
ENST00000321691.3
septin 4
chr21_-_26843012 5.30 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr14_-_21024092 5.29 ENST00000554398.5
NDRG family member 2
chrM_+_12329 5.25 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr20_-_51768327 5.23 ENST00000311637.9
ENST00000338821.6
ATPase phospholipid transporting 9A (putative)
chr15_-_83283449 5.20 ENST00000569704.2
basonuclin 1
chr18_-_55403682 5.15 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr2_-_51032091 5.11 ENST00000637511.1
ENST00000405472.7
ENST00000405581.3
ENST00000401669.7
neurexin 1
chr10_+_119819244 5.09 ENST00000637174.1
inositol polyphosphate-5-phosphatase F
chr12_+_78864768 5.07 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr22_+_39520553 5.04 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr20_-_54070520 5.00 ENST00000371435.6
ENST00000395961.7
brain enriched myelin associated protein 1
chr1_-_158554405 4.99 ENST00000641282.1
ENST00000641622.1
olfactory receptor family 6 subfamily Y member 1
chr16_+_30658399 4.95 ENST00000356166.11
fibrosin
chr12_+_123671105 4.88 ENST00000680574.1
ENST00000426174.6
ENST00000679504.1
ENST00000303372.7
tectonic family member 2
chr10_-_121598359 4.84 ENST00000684153.1
fibroblast growth factor receptor 2
chr6_-_107824294 4.83 ENST00000369020.8
ENST00000369022.6
Scm polycomb group protein like 4
chr17_+_39927724 4.76 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr11_+_94973640 4.73 ENST00000335080.6
ENST00000536741.1
lysine demethylase 4D
chr16_+_7303245 4.73 ENST00000674626.1
RNA binding fox-1 homolog 1
chr16_+_16379055 4.69 ENST00000530217.2
nuclear pore complex interacting protein family member A7
chr6_+_26087281 4.68 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
homeostatic iron regulator
chr12_-_6124662 4.62 ENST00000261405.10
von Willebrand factor
chr1_+_116111395 4.61 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr9_+_102995308 4.58 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr1_+_50106265 4.50 ENST00000357083.8
ELAV like RNA binding protein 4
chr3_-_49277209 4.48 ENST00000436325.1
ENST00000343010.8
chromosome 3 open reading frame 62
chr2_+_172928165 4.48 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chr21_+_38272291 4.45 ENST00000438657.5
potassium inwardly rectifying channel subfamily J member 15
chr17_-_69150062 4.43 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr1_+_152663378 4.40 ENST00000368784.2
late cornified envelope 2D
chr9_-_128067310 4.37 ENST00000373078.5
nuclear apoptosis inducing factor 1
chr1_+_92168915 4.36 ENST00000637221.2
BTB domain containing 8
chr7_+_45574358 4.32 ENST00000297323.12
adenylate cyclase 1
chr6_-_27807916 4.28 ENST00000377401.3
H2B clustered histone 13
chr4_-_39032343 4.24 ENST00000381938.4
transmembrane protein 156
chr3_+_41200104 4.24 ENST00000643297.1
ENST00000450969.6
catenin beta 1
chr5_+_95555134 4.23 ENST00000504763.1
arylsulfatase family member K
chr5_+_141370236 4.23 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr4_+_153222402 4.19 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr5_-_138875290 4.17 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr16_-_15378294 4.12 ENST00000360151.9
ENST00000543801.5
nuclear pore complex interacting protein family member A5
chr16_+_14711689 4.11 ENST00000552140.5
nuclear pore complex interacting protein family member A3
chr3_-_114759115 4.06 ENST00000471418.5
zinc finger and BTB domain containing 20
chr2_-_50347710 4.04 ENST00000342183.9
ENST00000401710.5
neurexin 1
chr6_+_25754699 4.04 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr6_+_27808163 4.01 ENST00000358739.4
H2A clustered histone 13
chr2_-_206086057 4.00 ENST00000403263.6
INO80 complex subunit D
chr6_+_26224192 3.95 ENST00000634733.1
H3 clustered histone 6
chr3_-_114758940 3.89 ENST00000464560.5
zinc finger and BTB domain containing 20
chr22_+_22906342 3.85 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr10_-_121598412 3.83 ENST00000360144.7
ENST00000358487.10
ENST00000369059.5
ENST00000613048.4
ENST00000356226.8
fibroblast growth factor receptor 2
chrX_-_10833643 3.82 ENST00000380785.5
ENST00000380787.5
midline 1
chr5_-_43412323 3.81 ENST00000361115.4
C-C motif chemokine ligand 28
chr1_+_151762899 3.79 ENST00000635322.1
ENST00000321531.10
ornithine decarboxylase antizyme 3
chr17_-_64263221 3.78 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr5_+_161848314 3.74 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr7_-_5513738 3.73 ENST00000453700.7
ENST00000382368.8
F-box and leucine rich repeat protein 18
chr9_+_101185029 3.73 ENST00000395056.2
phospholipid phosphatase related 1
chr10_+_73785571 3.71 ENST00000604729.6
ENST00000603114.5
ENST00000398706.6
ENST00000604524.5
ENST00000605216.5
zinc finger SWIM-type containing 8
chr8_-_94208548 3.70 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr16_+_56191476 3.63 ENST00000262493.12
G protein subunit alpha o1
chr6_+_118548289 3.60 ENST00000357525.6
phospholamban
chr10_-_60572599 3.54 ENST00000503366.5
ankyrin 3
chr22_-_44312894 3.50 ENST00000381176.5
shisa like 1
chr6_-_22302797 3.46 ENST00000651757.1
prolactin
chr16_-_11976611 3.46 ENST00000538896.5
ENST00000673243.1
nuclear pore complex interacting protein family member B2
chrX_-_115017569 3.45 ENST00000243213.2
interleukin 13 receptor subunit alpha 2
chr9_-_128322407 3.45 ENST00000372890.6
TruB pseudouridine synthase family member 2
chr5_+_161848112 3.43 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr5_+_162068031 3.43 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2
chr15_+_24823625 3.40 ENST00000400100.5
ENST00000645002.1
ENST00000642807.1
small nuclear ribonucleoprotein polypeptide N
chr12_-_18090185 3.40 ENST00000229002.6
ENST00000538724.6
RERG like
chr6_+_27815010 3.40 ENST00000621112.2
H2B clustered histone 14
chr19_-_36418625 3.34 ENST00000392161.4
ZFP82 zinc finger protein
chr19_+_735026 3.32 ENST00000592155.5
ENST00000590161.2
paralemmin
chr11_+_77034392 3.29 ENST00000528622.5
ENST00000622824.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
chr2_-_208146150 3.20 ENST00000260988.5
crystallin gamma B
chr6_-_99994173 3.18 ENST00000281806.7
ENST00000369212.2
melanin concentrating hormone receptor 2
chr5_-_177753206 3.16 ENST00000614127.4
ENST00000504518.1
family with sequence similarity 153 member A
chr15_-_78245683 3.16 ENST00000560817.5
acyl-CoA synthetase bubblegum family member 1
chr18_-_28177102 3.14 ENST00000413878.2
ENST00000269141.8
cadherin 2
chr12_-_55296569 3.11 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr5_-_139439488 3.08 ENST00000302060.10
DnaJ heat shock protein family (Hsp40) member C18
chr13_-_32538819 3.07 ENST00000674452.1
ENST00000674422.1
ENST00000674349.1
ENST00000674465.1
ENST00000674327.1
ENST00000505213.5
ENST00000357505.10
ENST00000399396.7
NEDD4 binding protein 2 like 2
chr1_+_215573775 3.06 ENST00000448333.1
potassium channel tetramerization domain containing 3
chr21_+_38272250 3.01 ENST00000398932.5
potassium inwardly rectifying channel subfamily J member 15
chr4_-_152679984 3.00 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr16_-_9943182 2.99 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr3_+_35680994 2.96 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr2_-_29223808 2.95 ENST00000642122.1
ALK receptor tyrosine kinase
chr16_+_11976709 2.94 ENST00000566228.6
sorting nexin 29
chr8_-_18808837 2.92 ENST00000286485.12
pleckstrin and Sec7 domain containing 3
chr4_+_70360751 2.86 ENST00000226460.5
submaxillary gland androgen regulated protein 3A
chr4_+_153222307 2.85 ENST00000675899.1
ENST00000675611.1
ENST00000674872.1
ENST00000676167.1
tripartite motif containing 2
chr1_+_26159071 2.83 ENST00000374268.5
family with sequence similarity 110 member D
chr8_+_109362453 2.83 ENST00000378402.10
PKHD1 like 1
chr12_-_81598360 2.80 ENST00000333447.11
ENST00000407050.8
PTPRF interacting protein alpha 2
chr2_-_151971750 2.80 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chrX_-_33211540 2.78 ENST00000357033.9
dystrophin
chr3_-_115071333 2.75 ENST00000462705.5
zinc finger and BTB domain containing 20
chr20_+_44355692 2.74 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr15_-_58279245 2.73 ENST00000558231.5
aldehyde dehydrogenase 1 family member A2
chr6_-_27814757 2.72 ENST00000333151.5
H2A clustered histone 14
chr6_-_56851888 2.69 ENST00000312431.10
ENST00000520645.5
dystonin
chr1_+_202348687 2.68 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr5_-_138139382 2.66 ENST00000265191.4
NME/NM23 family member 5
chr7_-_19117625 2.65 ENST00000242261.6
twist family bHLH transcription factor 1
chr4_+_70472189 2.64 ENST00000304887.6
mucin 7, secreted
chr15_+_70892443 2.62 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr3_+_159839847 2.62 ENST00000445224.6
schwannomin interacting protein 1
chrX_+_85244032 2.62 ENST00000373165.7
zinc finger protein 711

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.4 34.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
8.8 26.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
7.1 35.5 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
5.9 76.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
4.8 14.3 GO:0036292 DNA rewinding(GO:0036292)
4.0 11.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
3.9 11.6 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
3.4 20.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.9 29.3 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.7 21.3 GO:0001887 selenium compound metabolic process(GO:0001887)
2.4 7.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
2.2 8.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
2.0 8.0 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
1.9 11.3 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
1.7 5.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.7 16.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.6 16.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.6 6.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.6 3.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
1.6 9.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.6 4.7 GO:1904437 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
1.6 7.8 GO:2000542 negative regulation of gastrulation(GO:2000542)
1.5 16.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.4 23.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.3 2.6 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
1.3 5.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.3 3.8 GO:0015847 putrescine transport(GO:0015847)
1.2 3.7 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.2 3.6 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.2 4.7 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.1 5.6 GO:0070384 Harderian gland development(GO:0070384)
1.1 9.8 GO:1902037 positive regulation of hematopoietic stem cell proliferation(GO:1902035) negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.1 9.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.0 18.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.0 3.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.0 6.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.9 3.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 19.2 GO:0001502 cartilage condensation(GO:0001502)
0.8 4.2 GO:0060066 glial cell fate determination(GO:0007403) oviduct development(GO:0060066) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.7 3.0 GO:0036269 swimming behavior(GO:0036269)
0.7 12.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.7 2.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.7 6.1 GO:0015693 magnesium ion transport(GO:0015693)
0.7 3.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.7 6.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 17.3 GO:0071420 cellular response to histamine(GO:0071420)
0.6 1.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.6 5.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.6 3.0 GO:0033058 directional locomotion(GO:0033058)
0.6 3.4 GO:0097338 response to clozapine(GO:0097338)
0.6 1.7 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.6 1.7 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.5 3.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.5 2.2 GO:0009822 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.5 5.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.5 3.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.5 2.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.5 8.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.5 1.5 GO:1905237 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) response to cyclosporin A(GO:1905237)
0.5 2.0 GO:2000364 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.5 1.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.5 1.4 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.5 10.9 GO:0006183 GTP biosynthetic process(GO:0006183)
0.4 3.5 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.4 1.7 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.4 2.5 GO:0051012 microtubule sliding(GO:0051012)
0.4 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.4 3.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 1.2 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.4 3.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 1.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 13.8 GO:0018149 peptide cross-linking(GO:0018149)
0.4 1.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 5.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 6.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 1.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 2.0 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.3 1.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.3 1.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 22.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.3 2.4 GO:0008343 adult feeding behavior(GO:0008343)
0.3 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 2.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 0.9 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.3 2.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 4.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3 0.9 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 1.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 3.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 2.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.3 1.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.3 7.7 GO:0006825 copper ion transport(GO:0006825)
0.3 1.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 2.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2 1.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 15.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.2 1.4 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.2 2.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 2.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 16.3 GO:0030574 collagen catabolic process(GO:0030574)
0.2 3.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 2.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 2.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 2.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 3.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 10.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 10.6 GO:0010107 potassium ion import(GO:0010107)
0.2 5.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 4.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 4.7 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 1.8 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 4.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 3.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 2.5 GO:0035878 nail development(GO:0035878)
0.2 1.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 15.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.9 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 0.6 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 0.9 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.8 GO:0061743 motor learning(GO:0061743)
0.1 42.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 3.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.6 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 7.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.9 GO:0060004 reflex(GO:0060004)
0.1 0.4 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 1.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.4 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 1.2 GO:0070307 lens fiber cell development(GO:0070307)
0.1 3.6 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.6 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.4 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 1.9 GO:0051775 response to redox state(GO:0051775)
0.1 1.4 GO:0060134 prepulse inhibition(GO:0060134)
0.1 3.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.2 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.7 GO:0046449 creatinine metabolic process(GO:0046449)
0.1 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 2.1 GO:0016048 detection of temperature stimulus(GO:0016048)
0.1 0.8 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 5.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 4.6 GO:0009994 oocyte differentiation(GO:0009994)
0.1 3.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 5.1 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 4.9 GO:0014047 glutamate secretion(GO:0014047)
0.1 4.8 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 5.9 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.4 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.6 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 1.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.3 GO:1902514 positive regulation of adrenergic receptor signaling pathway(GO:0071879) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.1 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0001842 neural fold formation(GO:0001842)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.3 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.2 GO:2000296 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 3.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 3.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 7.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 4.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 2.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.8 GO:0046849 bone remodeling(GO:0046849)
0.0 0.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.2 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.8 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.8 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 1.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.8 GO:0033344 cholesterol efflux(GO:0033344)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 7.4 GO:0007601 visual perception(GO:0007601)
0.0 3.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 2.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 1.1 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 2.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.0 0.5 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 1.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 7.5 GO:0006397 mRNA processing(GO:0006397)
0.0 0.7 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.8 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 82.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
5.6 33.8 GO:0033269 internode region of axon(GO:0033269)
4.8 14.5 GO:0044609 DBIRD complex(GO:0044609)
2.6 7.8 GO:0005588 collagen type V trimer(GO:0005588)
2.4 11.9 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
2.2 32.8 GO:0030478 actin cap(GO:0030478)
2.0 23.7 GO:0005577 fibrinogen complex(GO:0005577)
1.5 4.6 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
1.4 5.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
1.2 23.6 GO:0031089 platelet dense granule lumen(GO:0031089)
1.2 13.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
1.0 9.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9 2.6 GO:0097679 other organism cytoplasm(GO:0097679)
0.8 4.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.8 11.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.8 11.9 GO:0005687 U4 snRNP(GO:0005687)
0.7 5.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.7 4.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.5 2.7 GO:0031673 H zone(GO:0031673)
0.5 9.5 GO:0033270 paranode region of axon(GO:0033270)
0.5 8.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 3.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 17.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.4 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 2.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.4 5.5 GO:0016342 catenin complex(GO:0016342)
0.3 47.7 GO:0032993 protein-DNA complex(GO:0032993)
0.3 20.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 17.3 GO:0043034 costamere(GO:0043034)
0.3 13.4 GO:0045095 keratin filament(GO:0045095)
0.3 19.9 GO:0005657 replication fork(GO:0005657)
0.3 12.0 GO:0001533 cornified envelope(GO:0001533)
0.3 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.3 4.9 GO:0036038 MKS complex(GO:0036038)
0.2 3.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 13.1 GO:0048786 presynaptic active zone(GO:0048786)
0.2 19.3 GO:0042734 presynaptic membrane(GO:0042734)
0.2 2.6 GO:0097427 microtubule bundle(GO:0097427)
0.2 9.3 GO:0097546 ciliary base(GO:0097546)
0.2 22.0 GO:0005604 basement membrane(GO:0005604)
0.2 55.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 33.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 0.9 GO:0071438 invadopodium membrane(GO:0071438)
0.2 2.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 2.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 4.7 GO:0035861 site of double-strand break(GO:0035861)
0.2 3.3 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.2 22.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.6 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 1.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0000805 X chromosome(GO:0000805)
0.1 1.3 GO:0070449 elongin complex(GO:0070449)
0.1 3.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 2.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 20.0 GO:0030426 growth cone(GO:0030426)
0.1 4.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 13.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 8.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 9.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 4.7 GO:0031904 endosome lumen(GO:0031904)
0.1 10.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.6 GO:0097450 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 5.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 34.5 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 3.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.6 GO:0031143 pseudopodium(GO:0031143)
0.1 11.3 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 6.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.7 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 4.5 GO:0098793 presynapse(GO:0098793)
0.0 1.1 GO:0071564 npBAF complex(GO:0071564)
0.0 7.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 5.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 2.0 GO:0044445 cytosolic part(GO:0044445)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 2.9 GO:0000790 nuclear chromatin(GO:0000790)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 21.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.9 11.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.8 33.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.7 56.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.4 11.9 GO:0030348 syntaxin-3 binding(GO:0030348)
2.1 29.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.9 5.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.8 21.3 GO:0008430 selenium binding(GO:0008430)
1.4 4.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.3 14.3 GO:0036310 annealing helicase activity(GO:0036310)
1.3 3.8 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.2 32.8 GO:0005523 tropomyosin binding(GO:0005523)
1.2 4.7 GO:0005148 prolactin receptor binding(GO:0005148)
1.1 138.0 GO:0005518 collagen binding(GO:0005518)
1.1 3.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
1.1 10.5 GO:0005549 odorant binding(GO:0005549)
1.0 8.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.9 11.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.9 3.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.8 7.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.8 5.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.7 2.2 GO:0035375 zymogen binding(GO:0035375)
0.7 3.7 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.7 2.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.7 8.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.7 16.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.7 8.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.7 27.5 GO:0017091 AU-rich element binding(GO:0017091)
0.6 1.9 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.6 5.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.6 1.8 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.6 7.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.6 6.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.6 8.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.6 10.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6 2.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.5 34.3 GO:0015485 cholesterol binding(GO:0015485)
0.5 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.5 9.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 3.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.5 2.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 5.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 1.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.4 2.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 1.7 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.4 4.7 GO:0039706 co-receptor binding(GO:0039706)
0.4 40.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 6.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.4 3.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 7.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 11.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 10.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.4 5.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 9.1 GO:0002162 dystroglycan binding(GO:0002162)
0.4 4.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 1.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 2.0 GO:0004882 androgen receptor activity(GO:0004882)
0.3 7.1 GO:0005112 Notch binding(GO:0005112)
0.3 20.3 GO:0030507 spectrin binding(GO:0030507)
0.3 5.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 2.8 GO:0004969 histamine receptor activity(GO:0004969)
0.3 4.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 0.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 3.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 5.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 2.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 3.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.2 2.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 15.4 GO:0070412 R-SMAD binding(GO:0070412)
0.2 10.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.7 GO:0005497 androgen binding(GO:0005497)
0.2 1.6 GO:0001515 opioid peptide activity(GO:0001515)
0.2 0.9 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 6.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 3.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 5.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 1.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 7.4 GO:0030332 cyclin binding(GO:0030332)
0.2 7.1 GO:0050699 WW domain binding(GO:0050699)
0.2 23.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.8 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 6.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 2.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 2.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 3.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 3.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1 0.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 4.7 GO:0008009 chemokine activity(GO:0008009)
0.1 4.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 5.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 3.8 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0043495 protein anchor(GO:0043495)
0.1 1.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 3.7 GO:0030552 cAMP binding(GO:0030552)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 13.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 4.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.0 5.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 2.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.8 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 3.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 5.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 1.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 4.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.9 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.0 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0008252 nucleotidase activity(GO:0008252)
0.0 1.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 86.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.0 26.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 28.7 NABA COLLAGENS Genes encoding collagen proteins
0.4 24.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 55.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.4 1.5 ST ADRENERGIC Adrenergic Pathway
0.4 21.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 3.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 12.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 5.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 3.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 7.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 9.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 7.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 11.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 15.9 PID FGF PATHWAY FGF signaling pathway
0.2 3.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 18.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 24.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 9.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 7.6 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 10.4 PID CDC42 PATHWAY CDC42 signaling events
0.1 6.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.8 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 4.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 17.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 76.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.2 30.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.0 53.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.8 62.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.8 18.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.8 9.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 18.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 11.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.4 7.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.4 28.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 32.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.4 4.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 12.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 4.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 2.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 5.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 9.8 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.3 6.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 17.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 7.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 4.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 1.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 5.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 3.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 4.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 1.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 7.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.4 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1 3.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 7.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 5.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 13.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 3.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 2.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)