Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for HOXC10_HOXD13
Z-value: 4.60
Motif logo
Transcription factors associated with HOXC10_HOXD13
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC10
|
ENSG00000180818.5 | HOXC10 |
|
HOXD13
|
ENSG00000128714.6 | HOXD13 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXD13 | hg38_v1_chr2_+_176092715_176092729 | 0.23 | 5.8e-04 | Click! |
| HOXC10 | hg38_v1_chr12_+_53985138_53985183 | -0.12 | 7.3e-02 | Click! |
Activity profile of HOXC10_HOXD13 motif
Sorted Z-values of HOXC10_HOXD13 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC10_HOXD13
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.4 | 34.3 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 8.8 | 26.3 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
| 7.1 | 35.5 | GO:1904209 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 5.9 | 76.2 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 4.8 | 14.3 | GO:0036292 | DNA rewinding(GO:0036292) |
| 4.0 | 11.9 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 3.9 | 11.6 | GO:1904395 | retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 3.4 | 20.4 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 2.9 | 29.3 | GO:0006537 | glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 2.7 | 21.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 2.4 | 7.1 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 2.2 | 8.8 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 2.0 | 8.0 | GO:1902159 | regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) |
| 1.9 | 11.3 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) |
| 1.7 | 5.0 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 1.7 | 16.7 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 1.6 | 16.1 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 1.6 | 6.4 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 1.6 | 3.2 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 1.6 | 9.5 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 1.6 | 4.7 | GO:1904437 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) |
| 1.6 | 7.8 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 1.5 | 16.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 1.4 | 23.4 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 1.3 | 2.6 | GO:2000793 | cell proliferation involved in heart valve development(GO:2000793) |
| 1.3 | 5.1 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 1.3 | 3.8 | GO:0015847 | putrescine transport(GO:0015847) |
| 1.2 | 3.7 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 1.2 | 3.6 | GO:1901876 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 1.2 | 4.7 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 1.1 | 5.6 | GO:0070384 | Harderian gland development(GO:0070384) |
| 1.1 | 9.8 | GO:1902037 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 1.1 | 9.5 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 1.0 | 18.8 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 1.0 | 3.0 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 1.0 | 6.9 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.9 | 3.5 | GO:1900827 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.9 | 19.2 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.8 | 4.2 | GO:0060066 | glial cell fate determination(GO:0007403) oviduct development(GO:0060066) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 0.7 | 3.0 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.7 | 12.2 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.7 | 2.1 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.7 | 6.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.7 | 3.3 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.7 | 6.6 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.6 | 17.3 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.6 | 1.9 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.6 | 5.5 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.6 | 3.0 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.6 | 3.4 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.6 | 1.7 | GO:0021780 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.6 | 1.7 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.5 | 3.8 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.5 | 2.2 | GO:0009822 | alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378) |
| 0.5 | 5.4 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.5 | 3.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.5 | 2.1 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.5 | 8.3 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.5 | 1.5 | GO:1905237 | immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) response to cyclosporin A(GO:1905237) |
| 0.5 | 2.0 | GO:2000364 | hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366) |
| 0.5 | 1.0 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.5 | 1.4 | GO:0002125 | maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925) |
| 0.5 | 10.9 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.4 | 3.5 | GO:0043305 | negative regulation of mast cell degranulation(GO:0043305) |
| 0.4 | 1.7 | GO:0018032 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.4 | 2.5 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.4 | 0.8 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.4 | 3.2 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.4 | 1.2 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.4 | 3.8 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.4 | 1.8 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.4 | 13.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.4 | 1.4 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.3 | 5.8 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.3 | 6.3 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.3 | 1.3 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.3 | 2.0 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) |
| 0.3 | 1.6 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.3 | 1.2 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.3 | 22.5 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.3 | 2.4 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.3 | 0.9 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.3 | 2.1 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.3 | 0.9 | GO:1990451 | cellular stress response to acidic pH(GO:1990451) |
| 0.3 | 2.3 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.3 | 4.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.3 | 0.9 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.3 | 1.1 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.3 | 3.9 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.3 | 2.7 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.3 | 1.1 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.3 | 7.7 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.3 | 1.3 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.2 | 2.0 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.2 | 1.9 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.2 | 15.8 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.2 | 1.4 | GO:0033029 | regulation of neutrophil apoptotic process(GO:0033029) |
| 0.2 | 2.7 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.2 | 2.2 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.2 | 0.9 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.2 | 16.3 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.2 | 3.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 2.8 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.2 | 1.7 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.2 | 2.3 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.2 | 2.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.2 | 3.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.2 | 10.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 10.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.2 | 5.2 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.2 | 4.0 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.2 | 4.7 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.2 | 1.8 | GO:0071799 | response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799) |
| 0.2 | 4.6 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.2 | 3.8 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.2 | 2.5 | GO:0035878 | nail development(GO:0035878) |
| 0.2 | 1.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.2 | 15.6 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.2 | 1.9 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
| 0.2 | 0.6 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.2 | 0.9 | GO:0038031 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.2 | 0.8 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 42.6 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 3.1 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 1.6 | GO:0015801 | aromatic amino acid transport(GO:0015801) |
| 0.1 | 7.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 0.7 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.1 | 1.9 | GO:0060004 | reflex(GO:0060004) |
| 0.1 | 0.4 | GO:0070845 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.1 | 1.2 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 1.4 | GO:0035437 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 0.1 | 1.2 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 3.6 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.1 | 0.6 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.1 | 0.4 | GO:0072366 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.1 | 1.9 | GO:0051775 | response to redox state(GO:0051775) |
| 0.1 | 1.4 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.1 | 3.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 2.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.2 | GO:0021730 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 0.4 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 0.1 | 0.6 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 0.7 | GO:0046449 | creatinine metabolic process(GO:0046449) |
| 0.1 | 0.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 2.1 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.1 | 0.8 | GO:0018410 | C-terminal protein amino acid modification(GO:0018410) |
| 0.1 | 5.2 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 0.5 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 4.6 | GO:0009994 | oocyte differentiation(GO:0009994) |
| 0.1 | 3.2 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.1 | 2.0 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.1 | 5.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 2.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 4.9 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 4.8 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.1 | 5.9 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
| 0.1 | 0.6 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 1.4 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.1 | 0.8 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 2.8 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 1.6 | GO:0045187 | regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.1 | 1.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 2.8 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.1 | 0.3 | GO:1902514 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 0.1 | 0.1 | GO:0061056 | sclerotome development(GO:0061056) |
| 0.1 | 0.8 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.1 | 0.3 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.1 | 0.3 | GO:0010578 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.1 | 2.1 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.1 | 0.2 | GO:2000296 | regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.1 | 3.6 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.1 | 0.2 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 1.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 0.8 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 1.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 3.4 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 2.4 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 7.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 4.0 | GO:0021954 | central nervous system neuron development(GO:0021954) |
| 0.0 | 0.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 2.1 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.0 | 3.8 | GO:0046849 | bone remodeling(GO:0046849) |
| 0.0 | 0.6 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.0 | 1.2 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.0 | 0.8 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.0 | 1.6 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.0 | 0.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.8 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 1.5 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 1.8 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 1.0 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 7.4 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 3.6 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 2.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 0.5 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.0 | 0.2 | GO:0010909 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.0 | 0.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.0 | 0.4 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) |
| 0.0 | 1.1 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.0 | 2.7 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.0 | 0.2 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.0 | 0.2 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.2 | GO:0030007 | cellular potassium ion homeostasis(GO:0030007) |
| 0.0 | 0.5 | GO:0043330 | response to exogenous dsRNA(GO:0043330) |
| 0.0 | 1.0 | GO:0030837 | negative regulation of actin filament polymerization(GO:0030837) |
| 0.0 | 0.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.0 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.0 | 7.5 | GO:0006397 | mRNA processing(GO:0006397) |
| 0.0 | 0.7 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 0.8 | GO:0035722 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
| 0.0 | 0.3 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.4 | 82.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 5.6 | 33.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 4.8 | 14.5 | GO:0044609 | DBIRD complex(GO:0044609) |
| 2.6 | 7.8 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 2.4 | 11.9 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 2.2 | 32.8 | GO:0030478 | actin cap(GO:0030478) |
| 2.0 | 23.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 1.5 | 4.6 | GO:0033150 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 1.4 | 5.7 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 1.2 | 23.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 1.2 | 13.0 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 1.0 | 9.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.9 | 2.6 | GO:0097679 | other organism cytoplasm(GO:0097679) |
| 0.8 | 4.1 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.8 | 11.5 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.8 | 11.9 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.7 | 5.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.7 | 4.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.5 | 2.7 | GO:0031673 | H zone(GO:0031673) |
| 0.5 | 9.5 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.5 | 8.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.5 | 3.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.4 | 17.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.4 | 2.0 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.4 | 2.8 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.4 | 5.5 | GO:0016342 | catenin complex(GO:0016342) |
| 0.3 | 47.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.3 | 20.7 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.3 | 17.3 | GO:0043034 | costamere(GO:0043034) |
| 0.3 | 13.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.3 | 19.9 | GO:0005657 | replication fork(GO:0005657) |
| 0.3 | 12.0 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.3 | 2.1 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.3 | 4.9 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 3.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 2.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 13.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 19.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.2 | 2.6 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 9.3 | GO:0097546 | ciliary base(GO:0097546) |
| 0.2 | 22.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 55.2 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.2 | 33.5 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.2 | 0.9 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.2 | 2.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.2 | 2.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 4.7 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.2 | 3.3 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 1.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.2 | 22.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 3.6 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.1 | 1.6 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 2.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 0.4 | GO:0000805 | X chromosome(GO:0000805) |
| 0.1 | 1.3 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 3.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 1.2 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 2.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 0.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 20.0 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 4.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 13.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 2.1 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 8.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.1 | 9.0 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 1.6 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 4.7 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.1 | 10.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 0.2 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 0.6 | GO:0097450 | astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451) |
| 0.1 | 5.4 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 34.5 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.1 | 0.8 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 3.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 1.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 1.6 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 11.3 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.1 | 0.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 0.5 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 6.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.2 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.0 | 3.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 2.7 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 0.9 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 1.4 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 4.5 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 1.1 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 7.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 5.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 2.2 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.9 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 2.0 | GO:0044445 | cytosolic part(GO:0044445) |
| 0.0 | 0.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 1.5 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 1.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.5 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 2.9 | GO:0000790 | nuclear chromatin(GO:0000790) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 21.0 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 2.9 | 11.6 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 2.8 | 33.8 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 2.7 | 56.6 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 2.4 | 11.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 2.1 | 29.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 1.9 | 5.6 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 1.8 | 21.3 | GO:0008430 | selenium binding(GO:0008430) |
| 1.4 | 4.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 1.3 | 14.3 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 1.3 | 3.8 | GO:0015203 | polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489) |
| 1.2 | 32.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 1.2 | 4.7 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 1.1 | 138.0 | GO:0005518 | collagen binding(GO:0005518) |
| 1.1 | 3.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 1.1 | 10.5 | GO:0005549 | odorant binding(GO:0005549) |
| 1.0 | 8.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.9 | 11.3 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.9 | 3.6 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.8 | 7.2 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.8 | 5.4 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.7 | 2.2 | GO:0035375 | zymogen binding(GO:0035375) |
| 0.7 | 3.7 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.7 | 2.2 | GO:0030343 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.7 | 8.5 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.7 | 16.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.7 | 8.8 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.7 | 27.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.6 | 1.9 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 0.6 | 5.1 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.6 | 1.8 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 0.6 | 7.5 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.6 | 6.9 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.6 | 8.0 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.6 | 10.6 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.6 | 2.8 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.5 | 34.3 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.5 | 1.5 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.5 | 9.7 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.5 | 3.0 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.5 | 2.0 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.5 | 5.5 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.4 | 1.3 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.4 | 2.6 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.4 | 1.7 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.4 | 4.7 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.4 | 40.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 6.4 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.4 | 3.1 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.4 | 7.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.4 | 11.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.4 | 10.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.4 | 5.9 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.4 | 9.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.4 | 4.2 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.3 | 1.7 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.3 | 2.0 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.3 | 7.1 | GO:0005112 | Notch binding(GO:0005112) |
| 0.3 | 20.3 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.3 | 5.0 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.3 | 2.8 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.3 | 4.0 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.3 | 0.9 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.3 | 3.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.3 | 5.6 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.3 | 2.0 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.2 | 3.7 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577) |
| 0.2 | 2.7 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.2 | 15.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.2 | 10.2 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.2 | 0.7 | GO:0005497 | androgen binding(GO:0005497) |
| 0.2 | 1.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.2 | 0.9 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.2 | 2.3 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.2 | 6.2 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.2 | 3.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 5.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 1.6 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 1.4 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 7.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.2 | 7.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 23.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 3.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.2 | 2.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.2 | 1.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 0.8 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.2 | 1.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.2 | 6.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.2 | 2.1 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.2 | 2.1 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.2 | 3.0 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 2.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 2.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 2.2 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.1 | 1.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 3.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 2.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.7 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 3.2 | GO:0042166 | acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166) |
| 0.1 | 0.9 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.1 | 1.4 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.1 | 4.7 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 4.0 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 2.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 3.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 5.3 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 0.9 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.1 | 3.8 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 1.6 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 1.7 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.1 | 3.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 1.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 13.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.2 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.1 | 2.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.9 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.2 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.1 | 0.3 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.1 | 0.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.1 | 1.1 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.1 | 1.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 1.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.0 | 1.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 4.0 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 1.1 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 0.6 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 5.0 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 4.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.3 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.0 | 2.1 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 1.2 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 1.5 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 2.8 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
| 0.0 | 0.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.2 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 1.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 1.1 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.5 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 3.8 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 5.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 1.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.1 | GO:0004339 | glucan 1,4-alpha-glucosidase activity(GO:0004339) |
| 0.0 | 1.3 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.0 | 4.2 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 0.8 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.0 | 0.5 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 1.9 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.2 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.0 | 0.6 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 2.0 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.6 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.0 | 1.5 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.8 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 1.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.0 | GO:0019862 | IgA binding(GO:0019862) |
| 0.0 | 0.2 | GO:0008252 | nucleotidase activity(GO:0008252) |
| 0.0 | 1.4 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 3.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.1 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 86.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 1.0 | 26.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.6 | 28.7 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.4 | 24.5 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.4 | 55.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.4 | 1.5 | ST ADRENERGIC | Adrenergic Pathway |
| 0.4 | 21.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.3 | 3.5 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.3 | 12.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.3 | 5.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.3 | 3.6 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.3 | 7.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.2 | 9.0 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.2 | 7.1 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.2 | 11.9 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.2 | 15.9 | PID FGF PATHWAY | FGF signaling pathway |
| 0.2 | 3.2 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 18.4 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 3.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.1 | 24.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 9.3 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 7.6 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 1.4 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 10.4 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 6.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 1.9 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.1 | 4.8 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 2.8 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 2.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 4.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 2.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 17.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.2 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 0.4 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 1.0 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.1 | 4.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.3 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 1.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.8 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.2 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 0.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.2 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 1.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 2.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.2 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.5 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 0.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.3 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 0.8 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 76.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 1.2 | 30.9 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 1.0 | 53.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.8 | 62.9 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.8 | 18.2 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.8 | 9.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.5 | 18.4 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.5 | 11.3 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.4 | 7.3 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.4 | 28.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.4 | 32.3 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.4 | 4.2 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.3 | 12.2 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.3 | 4.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.3 | 2.3 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.3 | 5.7 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.3 | 9.8 | REACTOME GABA B RECEPTOR ACTIVATION | Genes involved in GABA B receptor activation |
| 0.3 | 6.5 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.2 | 17.8 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.2 | 7.9 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.2 | 4.4 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.2 | 1.6 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.2 | 5.6 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.2 | 0.6 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.2 | 3.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 3.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.1 | 4.3 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 2.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 0.9 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.1 | 1.8 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 1.9 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 2.0 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 3.1 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 7.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 2.6 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.4 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 2.7 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 0.4 | REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | Genes involved in Incretin Synthesis, Secretion, and Inactivation |
| 0.1 | 3.4 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 3.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 7.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 1.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 5.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 13.4 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 2.8 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 1.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 1.6 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 3.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.8 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 1.2 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 2.2 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 2.6 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.1 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.4 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |