ISMARA results: HOXC6

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXC6_HOXA7

Z-value: 4.13

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Transcription factors associated with HOXC6_HOXA7

Gene Symbol	Gene ID	Gene Info
HOXC6 Ensembl NCBI GeneCards UniProt	ENSG00000197757.8	HOXC6
HOXA7 Ensembl NCBI GeneCards UniProt	ENSG00000122592.8	HOXA7

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXC6	hg38_v1_chr12_+_54028433_54028455	-0.23	6.4e-04	Click!
HOXA7	hg38_v1_chr7_-_27156646_27156693	0.10	1.5e-01	Click!

Activity profile of HOXC6_HOXA7 motif

Sorted Z-values of HOXC6_HOXA7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

View svg image
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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr19_+_49513353 Show fit	13.76	ENST00000596975.5	FCGRT Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor and transporter
chr2_-_89027700 Show fit	12.81	ENST00000483158.1	IGKV3-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-11
chr2_+_90038848 Show fit	12.61	ENST00000390270.2	IGKV3D-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr17_+_1771688 Show fit	11.83	ENST00000572048.1 ENST00000573763.1	SERPINF1 Ensembl NCBI GeneCards UniProt Show fit	serpin family F member 1
chr2_+_87338511 Show fit	11.39	ENST00000421835.2	IGKV3OR2-268 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr14_-_106470788 Show fit	11.29	ENST00000434710.1	IGHV3-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-43
chr2_+_90234809 Show fit	11.15	ENST00000443397.5	IGKV3D-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-7
chr2_-_88979016 Show fit	10.13	ENST00000390247.2	IGKV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_90172802 Show fit	9.64	ENST00000390277.3	IGKV3D-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-11
chr2_-_89143133 Show fit	9.25	ENST00000492167.1	IGKV3-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr1_-_92486916 Show fit	8.66	ENST00000294702.6	GFI1 Ensembl NCBI GeneCards UniProt Show fit	growth factor independent 1 transcriptional repressor
chr2_+_90209873 Show fit	8.55	ENST00000468879.1	IGKV1D-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-43
chr12_-_91179517 Show fit	8.35	ENST00000551354.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr9_+_122371036 Show fit	7.96	ENST00000619306.5 ENST00000426608.6 ENST00000223423.8	PTGS1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr3_-_39280021 Show fit	7.92	ENST00000399220.3	CX3CR1 Ensembl NCBI GeneCards UniProt Show fit	C-X3-C motif chemokine receptor 1
chr18_+_34976928 Show fit	7.90	ENST00000591734.5 ENST00000413393.5 ENST00000589180.5 ENST00000587359.5	MAPRE2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein RP/EB family member 2
chr6_-_41733690 Show fit	7.52	ENST00000419396.6 ENST00000678831.1 ENST00000394283.5	TFEB Ensembl NCBI GeneCards UniProt Show fit	transcription factor EB
chr12_-_91179355 Show fit	7.25	ENST00000550563.5 ENST00000546370.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr6_+_26365176 Show fit	7.19	ENST00000377708.7	BTN3A2 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A2
chr6_+_26365215 Show fit	6.96	ENST00000527422.5 ENST00000356386.6 ENST00000396948.5	BTN3A2 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A2
chr9_+_122370523 Show fit	6.82	ENST00000643810.1 ENST00000540753.6	PTGS1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr6_+_26365159 Show fit	6.77	ENST00000532865.5 ENST00000396934.7 ENST00000508906.6 ENST00000530653.5 ENST00000527417.5	BTN3A2 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A2
chr12_-_91179472 Show fit	6.76	ENST00000550099.5 ENST00000546391.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr18_+_34978244 Show fit	6.37	ENST00000436190.6	MAPRE2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein RP/EB family member 2
chr11_+_121576760 Show fit	5.24	ENST00000532694.5 ENST00000534286.5	SORL1 Ensembl NCBI GeneCards UniProt Show fit	sortilin related receptor 1
chr1_-_150765785 Show fit	5.16	ENST00000680311.1 ENST00000681728.1 ENST00000680288.1	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr14_-_89619118 Show fit	5.14	ENST00000345097.8 ENST00000555855.5 ENST00000555353.5	FOXN3 Ensembl NCBI GeneCards UniProt Show fit	forkhead box N3
chr13_+_30735523 Show fit	5.01	ENST00000380490.5	ALOX5AP Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr1_+_202348687 Show fit	4.81	ENST00000608999.6 ENST00000391959.5 ENST00000480184.5	PPP1R12B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12B
chr12_-_9869345 Show fit	4.79	ENST00000228438.3	CLEC2B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 2 member B
chr18_-_55423757 Show fit	4.02	ENST00000675707.1	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr5_+_40909490 Show fit	3.84	ENST00000313164.10	C7 Ensembl NCBI GeneCards UniProt Show fit	complement C7
chr9_+_122371014 Show fit	3.74	ENST00000362012.7	PTGS1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr6_-_41734160 Show fit	3.65	ENST00000424495.2 ENST00000420312.6	TFEB Ensembl NCBI GeneCards UniProt Show fit	transcription factor EB
chr5_+_36606355 Show fit	3.59	ENST00000681909.1 ENST00000513903.5 ENST00000681795.1 ENST00000680125.1 ENST00000612708.5 ENST00000680232.1 ENST00000681776.1 ENST00000681926.1 ENST00000679958.1 ENST00000265113.9 ENST00000504121.5 ENST00000512374.1 ENST00000613445.5 ENST00000679983.1	SLC1A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 3
chr8_-_30812867 Show fit	3.45	ENST00000518243.5	PPP2CB Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 catalytic subunit beta
chr12_-_10130241 Show fit	3.35	ENST00000353231.9 ENST00000525605.1	CLEC7A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chr16_+_11965234 Show fit	3.34	ENST00000562385.1	TNFRSF17 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 17
chr3_+_111999326 Show fit	3.27	ENST00000494932.1	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chrX_+_1591590 Show fit	3.25	ENST00000313871.9 ENST00000381261.8	AKAP17A Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 17A
chr6_+_26402237 Show fit	3.12	ENST00000476549.6 ENST00000450085.6 ENST00000425234.6 ENST00000427334.5 ENST00000506698.1 ENST00000289361.11	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A1
chr1_+_84181630 Show fit	3.11	ENST00000610457.1	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr4_-_46909235 Show fit	3.10	ENST00000505102.1 ENST00000355591.8	COX7B2 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 7B2
chr4_-_8871817 Show fit	3.08	ENST00000400677.5	HMX1 Ensembl NCBI GeneCards UniProt Show fit	H6 family homeobox 1
chr5_+_67004618 Show fit	3.04	ENST00000261569.11 ENST00000436277.5	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr3_+_111999189 Show fit	2.98	ENST00000455401.6	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr3_+_111998739 Show fit	2.98	ENST00000393917.6 ENST00000273368.8	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr3_+_158801926 Show fit	2.93	ENST00000622669.4 ENST00000392813.8 ENST00000415822.8 ENST00000651862.1 ENST00000264266.12	MFSD1 Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 1
chr16_+_11965193 Show fit	2.85	ENST00000053243.6 ENST00000396495.3	TNFRSF17 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 17
chr7_-_150323489 Show fit	2.83	ENST00000683684.1 ENST00000478393.5	ACTR3C Ensembl NCBI GeneCards UniProt Show fit	actin related protein 3C
chr19_-_35812838 Show fit	2.79	ENST00000653904.2	PRODH2 Ensembl NCBI GeneCards UniProt Show fit	proline dehydrogenase 2
chr11_-_117316230 Show fit	2.67	ENST00000313005.11 ENST00000528053.5	BACE1 Ensembl NCBI GeneCards UniProt Show fit	beta-secretase 1
chr6_+_26440472 Show fit	2.65	ENST00000494393.5 ENST00000482451.5 ENST00000471353.5 ENST00000361232.7 ENST00000487627.5 ENST00000496719.1 ENST00000244519.7 ENST00000490254.5 ENST00000487272.1	BTN3A3 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A3
chr12_-_10130143 Show fit	2.61	ENST00000298523.9 ENST00000396484.6 ENST00000310002.4 ENST00000304084.13	CLEC7A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chr15_+_24823625 Show fit	2.44	ENST00000400100.5 ENST00000645002.1 ENST00000642807.1	SNRPN Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide N
chrX_+_10158448 Show fit	2.41	ENST00000380829.5 ENST00000421085.7 ENST00000674669.1 ENST00000454850.1	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 4
chr16_-_28623560 Show fit	2.26	ENST00000350842.8	SULT1A1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1A member 1
chr17_-_75667165 Show fit	2.25	ENST00000584999.1 ENST00000420326.6 ENST00000340830.9	RECQL5 Ensembl NCBI GeneCards UniProt Show fit	RecQ like helicase 5
chr11_+_60056653 Show fit	2.16	ENST00000278865.8	MS4A3 Ensembl NCBI GeneCards UniProt Show fit	membrane spanning 4-domains A3
chr6_+_113857333 Show fit	2.14	ENST00000612661.2	MARCKS Ensembl NCBI GeneCards UniProt Show fit	myristoylated alanine rich protein kinase C substrate
chr13_+_53028806 Show fit	2.14	ENST00000219022.3	OLFM4 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 4
chr3_+_178419123 Show fit	2.13	ENST00000614557.1 ENST00000455307.5 ENST00000436432.1	ENSG00000275163.1 Ensembl NCBI GeneCards UniProt Show fit LINC01014 Ensembl NCBI GeneCards UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript) long intergenic non-protein coding RNA 1014
chr8_-_33567118 Show fit	2.04	ENST00000256257.2	RNF122 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 122
chr1_-_113871665 Show fit	2.02	ENST00000528414.5 ENST00000460620.5 ENST00000359785.10 ENST00000420377.6 ENST00000525799.1 ENST00000538253.5	PTPN22 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 22
chr3_+_111998915 Show fit	2.01	ENST00000478951.6	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr15_+_58138368 Show fit	1.94	ENST00000219919.9 ENST00000536493.1	AQP9 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr6_+_26402289 Show fit	1.81	ENST00000414912.2	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A1
chr5_-_41213505 Show fit	1.81	ENST00000337836.10 ENST00000433294.1	C6 Ensembl NCBI GeneCards UniProt Show fit	complement C6
chr1_+_84144260 Show fit	1.80	ENST00000370685.7	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr12_+_56041893 Show fit	1.78	ENST00000552361.1 ENST00000646449.2	RPS26 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S26
chr2_+_24793098 Show fit	1.76	ENST00000473706.5	CENPO Ensembl NCBI GeneCards UniProt Show fit	centromere protein O
chr13_-_109786567 Show fit	1.76	ENST00000375856.5	IRS2 Ensembl NCBI GeneCards UniProt Show fit	insulin receptor substrate 2
chr6_-_109381739 Show fit	1.75	ENST00000504373.2	CD164 Ensembl NCBI GeneCards UniProt Show fit	CD164 molecule
chr11_+_60056587 Show fit	1.73	ENST00000395032.6 ENST00000358152.6	MS4A3 Ensembl NCBI GeneCards UniProt Show fit	membrane spanning 4-domains A3
chr1_-_37554277 Show fit	1.68	ENST00000296215.8	SNIP1 Ensembl NCBI GeneCards UniProt Show fit	Smad nuclear interacting protein 1
chrX_+_43656289 Show fit	1.66	ENST00000338702.4	MAOA Ensembl NCBI GeneCards UniProt Show fit	monoamine oxidase A
chr20_-_37178966 Show fit	1.53	ENST00000422138.1	MROH8 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 8
chr16_+_28553908 Show fit	1.53	ENST00000317058.8	SGF29 Ensembl NCBI GeneCards UniProt Show fit	SAGA complex associated factor 29
chr7_+_150323239 Show fit	1.48	ENST00000323078.7 ENST00000493307.1 ENST00000359623.9	LRRC61 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 61
chr2_+_201233443 Show fit	1.42	ENST00000392263.6 ENST00000264274.13 ENST00000432109.6 ENST00000264275.9 ENST00000450491.5 ENST00000440732.5 ENST00000392258.7	CASP8 Ensembl NCBI GeneCards UniProt Show fit	caspase 8
chr7_+_130266847 Show fit	1.42	ENST00000222481.9	CPA2 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A2
chr15_-_55365231 Show fit	1.41	ENST00000568543.1	CCPG1 Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chrX_-_107118783 Show fit	1.33	ENST00000372487.5 ENST00000372479.7	RBM41 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 41
chr14_+_71933116 Show fit	1.31	ENST00000553530.5 ENST00000556437.5	RGS6 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 6
chrX_-_14029877 Show fit	1.29	ENST00000680255.1 ENST00000380523.8 ENST00000398355.7	GEMIN8 Ensembl NCBI GeneCards UniProt Show fit	gem nuclear organelle associated protein 8
chr10_-_97445850 Show fit	1.29	ENST00000477692.6 ENST00000485122.6 ENST00000370886.9 ENST00000370885.8 ENST00000370902.8 ENST00000370884.5	EXOSC1 Ensembl NCBI GeneCards UniProt Show fit	exosome component 1
chr4_+_70242583 Show fit	1.28	ENST00000304954.3	CSN3 Ensembl NCBI GeneCards UniProt Show fit	casein kappa
chr4_-_86360010 Show fit	1.27	ENST00000641911.1 ENST00000641072.1 ENST00000359221.8 ENST00000640490.1	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr2_-_25168571 Show fit	1.23	ENST00000264708.7 ENST00000449220.1 ENST00000395826.7	POMC Ensembl NCBI GeneCards UniProt Show fit	proopiomelanocortin
chr2_+_206159580 Show fit	1.19	ENST00000236957.9 ENST00000392221.5 ENST00000445505.5	EEF1B2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 beta 2
chr14_-_94323324 Show fit	1.17	ENST00000341584.4	SERPINA6 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 6
chr2_-_25168903 Show fit	1.17	ENST00000405623.5	POMC Ensembl NCBI GeneCards UniProt Show fit	proopiomelanocortin
chr2_-_25168690 Show fit	1.15	ENST00000380794.5	POMC Ensembl NCBI GeneCards UniProt Show fit	proopiomelanocortin
chr6_+_106360668 Show fit	1.10	ENST00000633556.3	CRYBG1 Ensembl NCBI GeneCards UniProt Show fit	crystallin beta-gamma domain containing 1
chr19_-_54313074 Show fit	1.10	ENST00000486742.2 ENST00000432233.8	LILRA5 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor A5
chr1_+_62597510 Show fit	1.10	ENST00000371129.4	ANGPTL3 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin like 3
chr6_+_111087495 Show fit	1.09	ENST00000612036.4 ENST00000368851.10	SLC16A10 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 10
chr7_-_102579796 Show fit	1.09	ENST00000538869.2	RASA4 Ensembl NCBI GeneCards UniProt Show fit	RAS p21 protein activator 4
chr13_-_35855758 Show fit	1.04	ENST00000615680.4	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr2_+_168901290 Show fit	1.01	ENST00000429379.2 ENST00000375363.8 ENST00000421979.1	G6PC2 Ensembl NCBI GeneCards UniProt Show fit	glucose-6-phosphatase catalytic subunit 2
chr2_+_206159884 Show fit	1.01	ENST00000392222.7	EEF1B2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 beta 2
chr10_+_113126670 Show fit	0.88	ENST00000369389.6	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr21_-_30166782 Show fit	0.88	ENST00000286808.5	CLDN17 Ensembl NCBI GeneCards UniProt Show fit	claudin 17
chr16_-_28623330 Show fit	0.87	ENST00000677940.1	ENSG00000288656.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr4_-_119322128 Show fit	0.87	ENST00000274024.4	FABP2 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 2
chr11_-_13496018 Show fit	0.85	ENST00000529816.1	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr6_+_96521796 Show fit	0.84	ENST00000369278.5	UFL1 Ensembl NCBI GeneCards UniProt Show fit	UFM1 specific ligase 1
chr17_-_5035418 Show fit	0.82	ENST00000254853.10 ENST00000424747.1	SLC52A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 52 member 1
chr7_-_44541262 Show fit	0.81	ENST00000289547.8 ENST00000546276.5 ENST00000423141.1	NPC1L1 Ensembl NCBI GeneCards UniProt Show fit	NPC1 like intracellular cholesterol transporter 1
chr3_-_54928044 Show fit	0.79	ENST00000273286.6	LRTM1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and transmembrane domains 1
chr3_-_167474026 Show fit	0.78	ENST00000466903.1 ENST00000264677.8	SERPINI2 Ensembl NCBI GeneCards UniProt Show fit	serpin family I member 2
chr7_-_44541318 Show fit	0.76	ENST00000381160.8	NPC1L1 Ensembl NCBI GeneCards UniProt Show fit	NPC1 like intracellular cholesterol transporter 1
chr11_-_36598221 Show fit	0.75	ENST00000311485.8 ENST00000527033.5 ENST00000532616.1 ENST00000618712.4	RAG2 Ensembl NCBI GeneCards UniProt Show fit	recombination activating 2
chr8_-_92103217 Show fit	0.74	ENST00000615601.4 ENST00000523629.5	RUNX1T1 Ensembl NCBI GeneCards UniProt Show fit	RUNX1 partner transcriptional co-repressor 1
chr12_-_89526164 Show fit	0.73	ENST00000548729.5	POC1B-GALNT4 Ensembl NCBI GeneCards UniProt Show fit	POC1B-GALNT4 readthrough
chr12_-_89526253 Show fit	0.71	ENST00000547474.1	POC1B-GALNT4 Ensembl NCBI GeneCards UniProt Show fit	POC1B-GALNT4 readthrough
chr7_-_22822779 Show fit	0.68	ENST00000372879.8	TOMM7 Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 7
chr17_-_10469558 Show fit	0.67	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr18_-_49492305 Show fit	0.67	ENST00000615479.4 ENST00000583637.5 ENST00000618613.5 ENST00000615760.4 ENST00000578528.1 ENST00000578532.5 ENST00000580387.5 ENST00000579248.5 ENST00000580261.6 ENST00000581373.5 ENST00000618619.4 ENST00000617346.4 ENST00000583036.5 ENST00000332968.11	RPL17 Ensembl NCBI GeneCards UniProt Show fit RPL17-C18orf32 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L17 RPL17-C18orf32 readthrough
chr12_+_119668109 Show fit	0.67	ENST00000229328.10 ENST00000630317.1	PRKAB1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit beta 1
chr20_+_45416551 Show fit	0.65	ENST00000639292.1	PIGT Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class T
chr9_-_5339874 Show fit	0.63	ENST00000223862.2	RLN1 Ensembl NCBI GeneCards UniProt Show fit	relaxin 1
chr6_+_28124596 Show fit	0.61	ENST00000340487.5	ZSCAN16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and SCAN domain containing 16
chr1_+_205256189 Show fit	0.60	ENST00000329800.7	TMCC2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domain family 2
chr4_-_169612571 Show fit	0.58	ENST00000507142.6 ENST00000510533.5 ENST00000439128.6 ENST00000511633.5 ENST00000512193.5	NEK1 Ensembl NCBI GeneCards UniProt Show fit	NIMA related kinase 1
chrX_-_18672101 Show fit	0.55	ENST00000379984.4	RS1 Ensembl NCBI GeneCards UniProt Show fit	retinoschisin 1
chr10_+_52128343 Show fit	0.52	ENST00000672084.1	PRKG1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase cGMP-dependent 1
chr6_+_44387686 Show fit	0.50	ENST00000371477.4	CDC5L Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 5 like
chr5_-_20575850 Show fit	0.50	ENST00000507958.5	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18
chr18_-_13915531 Show fit	0.49	ENST00000327606.4	MC2R Ensembl NCBI GeneCards UniProt Show fit	melanocortin 2 receptor
chr19_+_48695952 Show fit	0.49	ENST00000522966.2 ENST00000425340.3 ENST00000391876.5	FUT2 Ensembl NCBI GeneCards UniProt Show fit	fucosyltransferase 2
chr2_+_201183120 Show fit	0.44	ENST00000272879.9 ENST00000286186.11 ENST00000374650.7 ENST00000346817.9 ENST00000313728.11 ENST00000448480.1	CASP10 Ensembl NCBI GeneCards UniProt Show fit	caspase 10
chr10_+_18260715 Show fit	0.44	ENST00000615785.4 ENST00000617363.4 ENST00000396576.6	CACNB2 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit beta 2
chr12_-_52367478 Show fit	0.44	ENST00000257901.7	KRT85 Ensembl NCBI GeneCards UniProt Show fit	keratin 85
chr8_-_41309434 Show fit	0.43	ENST00000220772.8	SFRP1 Ensembl NCBI GeneCards UniProt Show fit	secreted frizzled related protein 1
chr11_+_33039996 Show fit	0.43	ENST00000432887.5 ENST00000528898.1 ENST00000531632.6	TCP11L1 Ensembl NCBI GeneCards UniProt Show fit	t-complex 11 like 1
chr2_+_201182873 Show fit	0.41	ENST00000360132.7	CASP10 Ensembl NCBI GeneCards UniProt Show fit	caspase 10
chr6_+_128883114 Show fit	0.41	ENST00000421865.3 ENST00000618192.4 ENST00000617695.4	LAMA2 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 2
chr7_-_22822829 Show fit	0.40	ENST00000358435.9 ENST00000621567.1	TOMM7 Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 7
chr15_+_90872862 Show fit	0.39	ENST00000618099.4	FURIN Ensembl NCBI GeneCards UniProt Show fit	furin, paired basic amino acid cleaving enzyme
chr4_-_86360039 Show fit	0.38	ENST00000515650.2 ENST00000641724.1 ENST00000641607.1 ENST00000641324.1 ENST00000641903.1 ENST00000395157.9 ENST00000641823.1 ENST00000641873.1 ENST00000641102.1 ENST00000641462.2 ENST00000641217.1 ENST00000642006.1 ENST00000641020.1 ENST00000641110.1 ENST00000639175.1 ENST00000641485.1 ENST00000641864.1 ENST00000641954.1 ENST00000641647.1 ENST00000641459.1 ENST00000641762.1 ENST00000641777.1 ENST00000641208.1 ENST00000642015.1 ENST00000641493.1 ENST00000642032.1 ENST00000641010.1 ENST00000641287.1 ENST00000641943.1 ENST00000642103.1 ENST00000641047.1 ENST00000641166.1 ENST00000641207.1	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr11_-_129024157 Show fit	0.37	ENST00000392657.7	ARHGAP32 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 32
chr12_-_9999176 Show fit	0.36	ENST00000298527.10 ENST00000348658.4	CLEC1B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 1 member B
chr6_-_33192454 Show fit	0.36	ENST00000395194.1 ENST00000341947.7 ENST00000374708.8	COL11A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type XI alpha 2 chain
chr1_+_117420597 Show fit	0.35	ENST00000449370.6	MAN1A2 Ensembl NCBI GeneCards UniProt Show fit	mannosidase alpha class 1A member 2
chr7_+_134843884 Show fit	0.34	ENST00000445569.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr11_+_66509079 Show fit	0.33	ENST00000419755.3	ENSG00000256349.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr17_-_74776323 Show fit	0.31	ENST00000582870.5 ENST00000581136.5 ENST00000579218.5 ENST00000583476.5 ENST00000580301.5 ENST00000583757.5 ENST00000357814.8 ENST00000582524.5	NAT9 Ensembl NCBI GeneCards UniProt Show fit	N-acetyltransferase 9 (putative)
chr11_+_2384603 Show fit	0.30	ENST00000527343.5 ENST00000464784.6	CD81 Ensembl NCBI GeneCards UniProt Show fit	CD81 molecule
chr1_-_211134135 Show fit	0.29	ENST00000638983.1 ENST00000271751.10 ENST00000639952.1	ENSG00000284299.1 Ensembl NCBI GeneCards UniProt Show fit KCNH1 Ensembl NCBI GeneCards UniProt Show fit	novel protein potassium voltage-gated channel subfamily H member 1
chr14_-_22957100 Show fit	0.21	ENST00000555367.5	HAUS4 Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 4
chr6_-_34671918 Show fit	0.20	ENST00000374021.1	ILRUN Ensembl NCBI GeneCards UniProt Show fit	inflammation and lipid regulator with UBA-like and NBR1-like domains
chr5_+_55160161 Show fit	0.17	ENST00000296734.6 ENST00000515370.1 ENST00000503787.6	GPX8 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 8 (putative)
chr7_-_32299287 Show fit	0.15	ENST00000396193.5	PDE1C Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1C
chr19_-_14835162 Show fit	0.12	ENST00000322301.5	OR7A5 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 7 subfamily A member 5
chr14_-_22957061 Show fit	0.11	ENST00000557591.5 ENST00000541587.6 ENST00000490506.5 ENST00000554406.1	HAUS4 Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 4
chr3_+_45886501 Show fit	0.11	ENST00000395963.2	CCR9 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor 9
chrX_+_83861126 Show fit	0.02	ENST00000621735.4 ENST00000329312.5	CYLC1 Ensembl NCBI GeneCards UniProt Show fit	cylicin 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.6	13.8	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
2.9	8.7	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.0	7.9	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.7	5.2	GO:1902948	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.7	5.2	GO:0034769	basement membrane disassembly(GO:0034769)
1.7	22.4	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.7	11.8	GO:0071279	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.9	2.8	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.9	27.9	GO:0072643	interferon-gamma secretion(GO:0072643)
0.9	18.5	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.8	4.9	GO:0097338	response to clozapine(GO:0097338)
0.6	2.3	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.5	3.6	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.5	1.9	GO:0015855	canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.5	1.8	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4	5.0	GO:2001300	lipoxin metabolic process(GO:2001300)
0.4	0.8	GO:0002329	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.4	3.6	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4	1.4	GO:0052056	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.3	49.8	GO:0006958	complement activation, classical pathway(GO:0006958)
0.3	1.5	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.3	1.8	GO:0010748	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.3	6.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.3	1.4	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3	50.2	GO:0002377	immunoglobulin production(GO:0002377)
0.2	5.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.2	0.9	GO:0090290	hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2	2.1	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.2	11.2	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2	0.5	GO:1990637	response to prolactin(GO:1990637)
0.1	0.4	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1	1.1	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.1	0.9	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.1	1.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.8	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	2.3	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.8	GO:0032218	riboflavin transport(GO:0032218)
0.1	1.6	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	1.7	GO:0042420	dopamine catabolic process(GO:0042420)
0.1	1.7	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	1.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.1	0.4	GO:0090472	viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1	0.4	GO:0060023	soft palate development(GO:0060023)
0.1	0.3	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.1	2.1	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.7	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	0.5	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	1.6	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1	5.1	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	2.8	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	2.7	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.1	4.4	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.1	2.4	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	0.7	GO:0035878	nail development(GO:0035878)
0.0	0.5	GO:0009642	response to light intensity(GO:0009642)
0.0	0.4	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	1.8	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.1	GO:0002304	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0	0.5	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	1.2	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	1.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	1.3	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.9	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	1.0	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	1.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	1.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.6	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	3.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.9	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	1.3	GO:0007595	lactation(GO:0007595)
0.0	4.2	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.4	GO:0030220	platelet formation(GO:0030220)
0.0	1.7	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	2.2	GO:0045471	response to ethanol(GO:0045471)
0.0	1.1	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.0	0.7	GO:0014823	response to activity(GO:0014823)
0.0	0.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	7.9	GO:0051301	cell division(GO:0051301)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	9.3	GO:0071756	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.7	22.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1	11.8	GO:0043203	axon hillock(GO:0043203)
0.9	2.7	GO:0070931	Golgi-associated vesicle lumen(GO:0070931)
0.7	5.2	GO:0036021	endolysosome lumen(GO:0036021)
0.7	5.6	GO:0005579	membrane attack complex(GO:0005579)
0.4	13.2	GO:0035371	microtubule plus-end(GO:0035371)
0.3	5.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.2	4.9	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.2	7.9	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2	11.3	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	2.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	3.1	GO:0045277	respiratory chain complex IV(GO:0045277)
0.2	1.3	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.2	18.0	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	0.7	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	2.4	GO:0005687	U4 snRNP(GO:0005687)
0.1	2.1	GO:0043073	germ cell nucleus(GO:0043073)
0.1	2.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	1.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	0.4	GO:0005592	collagen type XI trimer(GO:0005592)
0.1	2.3	GO:0097342	ripoptosome(GO:0097342)
0.1	1.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	1.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.1	3.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	1.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.9	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	12.8	GO:0072562	blood microparticle(GO:0072562)
0.1	1.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	9.4	GO:0016363	nuclear matrix(GO:0016363)
0.1	4.8	GO:0031672	A band(GO:0031672)
0.0	0.7	GO:0032982	myosin filament(GO:0032982)
0.0	0.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	73.5	GO:0005615	extracellular space(GO:0005615)
0.0	0.3	GO:0030478	actin cap(GO:0030478)
0.0	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.0	3.9	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.5	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.4	GO:0005605	basal lamina(GO:0005605)
0.0	1.6	GO:0031526	brush border membrane(GO:0031526)
0.0	1.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	4.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	2.3	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	0.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	1.8	GO:0031902	late endosome membrane(GO:0031902)
0.0	2.0	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	51.4	GO:0016021	integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	18.5	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
3.4	13.8	GO:0019770	IgG receptor activity(GO:0019770)
2.0	7.9	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
1.2	3.6	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
1.0	5.0	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.7	2.7	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.6	1.9	GO:0015265	urea channel activity(GO:0015265)
0.4	2.3	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4	2.3	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.4	2.3	GO:0009378	four-way junction helicase activity(GO:0009378)
0.3	1.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3	5.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.3	75.6	GO:0003823	antigen binding(GO:0003823)
0.3	27.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.3	4.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.3	3.6	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	6.0	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2	4.0	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.7	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	0.7	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	1.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	13.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.5	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	1.6	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.8	GO:0032217	riboflavin transporter activity(GO:0032217)
0.1	2.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.3	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.1	3.1	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.5	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	2.8	GO:0071949	FAD binding(GO:0071949)
0.1	1.1	GO:0015266	protein channel activity(GO:0015266)
0.1	2.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.5	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	1.6	GO:0031489	myosin V binding(GO:0031489)
0.1	2.3	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.5	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	3.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	11.8	GO:0051015	actin filament binding(GO:0051015)
0.0	0.7	GO:0000146	microfilament motor activity(GO:0000146)
0.0	8.7	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.9	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	3.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.9	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	12.1	GO:0008017	microtubule binding(GO:0008017)
0.0	0.5	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.6	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	1.3	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	3.1	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	5.6	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	3.0	GO:0000287	magnesium ion binding(GO:0000287)
0.0	2.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	2.5	GO:0003735	structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	21.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	3.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	4.9	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	17.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	11.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.8	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.6	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	1.6	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	4.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	2.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.5	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	1.1	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	22.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.5	5.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	23.7	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.2	3.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2	2.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	4.9	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	1.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	5.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.1	8.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	4.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	2.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.5	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	1.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling

Results for HOXC6_HOXA7

Z-value: 4.13

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Transcription factors associated with HOXC6_HOXA7

Activity-expression correlation:

Activity profile of HOXC6_HOXA7 motif

Sorted Z-values of HOXC6_HOXA7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: