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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXC9

Z-value: 1.32

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Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
HOXC9
ENSG00000180806.5 HOXC9

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_68815991 7.61 ENST00000265403.12
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase family 2 member B10
chr8_-_63026179 6.53 ENST00000677919.1
GGH
gamma-glutamyl hydrolase
chr18_+_34978244 5.53 ENST00000436190.6
MAPRE2
microtubule associated protein RP/EB family member 2
chr1_-_197146620 5.45 ENST00000367409.9
ENST00000680265.1
ASPM
assembly factor for spindle microtubules
chr1_-_197146688 5.13 ENST00000294732.11
ASPM
assembly factor for spindle microtubules
chr5_+_36606355 5.12 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr1_+_163069353 4.85 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
RGS4
regulator of G protein signaling 4
chrX_-_13817027 4.66 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
GPM6B
glycoprotein M6B
chr2_+_186506713 4.13 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr7_+_65373839 4.01 ENST00000431504.1
ENST00000328747.12
ZNF92
zinc finger protein 92
chr7_+_65373873 3.97 ENST00000450302.2
ZNF92
zinc finger protein 92
chr1_+_220690354 3.78 ENST00000294889.6
C1orf115
chromosome 1 open reading frame 115
chr14_+_52707192 3.78 ENST00000445930.7
ENST00000555339.5
ENST00000556813.1
PSMC6
proteasome 26S subunit, ATPase 6
chr17_+_50746614 3.73 ENST00000513969.5
ENST00000503728.1
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chr1_-_212791762 3.68 ENST00000626725.1
ENST00000366977.8
ENST00000366976.3
NSL1
NSL1 component of MIS12 kinetochore complex
chr2_-_49973939 3.64 ENST00000630656.1
NRXN1
neurexin 1
chr4_-_69214743 3.64 ENST00000446444.2
UGT2B11
UDP glucuronosyltransferase family 2 member B11
chr14_+_52707178 3.62 ENST00000612399.4
PSMC6
proteasome 26S subunit, ATPase 6
chr10_-_116849686 3.62 ENST00000674167.1
ENST00000674401.1
ENST00000674326.1
ENST00000674267.1
ENST00000635765.1
HSPA12A
heat shock protein family A (Hsp70) member 12A
chr8_-_80171496 3.57 ENST00000379096.9
ENST00000518937.6
TPD52
tumor protein D52
chr1_+_92168915 3.54 ENST00000637221.2
BTBD8
BTB domain containing 8
chr13_-_23433676 3.51 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
SACS
sacsin molecular chaperone
chr12_-_62935117 3.39 ENST00000228705.7
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr6_+_29301701 3.31 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr10_-_13302341 3.27 ENST00000396920.7
PHYH
phytanoyl-CoA 2-hydroxylase
chr8_-_80080816 3.27 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
TPD52
tumor protein D52
chr1_-_158686700 3.20 ENST00000643759.2
SPTA1
spectrin alpha, erythrocytic 1
chr12_-_89656093 3.20 ENST00000359142.7
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr12_-_30735014 3.12 ENST00000433722.6
CAPRIN2
caprin family member 2
chr12_-_89656051 3.12 ENST00000261173.6
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr10_-_125816596 3.04 ENST00000368786.5
UROS
uroporphyrinogen III synthase
chr9_-_92293674 3.02 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
IARS1
isoleucyl-tRNA synthetase 1
chr5_+_157269317 3.01 ENST00000618329.4
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr9_-_101442403 2.99 ENST00000648758.1
ALDOB
aldolase, fructose-bisphosphate B
chrX_+_106693838 2.94 ENST00000324342.7
RNF128
ring finger protein 128
chr11_-_60906564 2.93 ENST00000541371.5
ENST00000227524.9
PRPF19
pre-mRNA processing factor 19
chr19_-_47471886 2.88 ENST00000236877.11
ENST00000597014.1
SLC8A2
solute carrier family 8 member A2
chr7_+_80646305 2.86 ENST00000426978.5
ENST00000432207.5
CD36
CD36 molecule
chr10_+_60778331 2.84 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
CDK1
cyclin dependent kinase 1
chr18_+_58341038 2.81 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr2_-_223602284 2.72 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
SCG2
secretogranin II
chr8_-_18684033 2.72 ENST00000614430.3
PSD3
pleckstrin and Sec7 domain containing 3
chr18_+_58196736 2.66 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr8_+_131904071 2.66 ENST00000254624.10
ENST00000522709.5
EFR3A
EFR3 homolog A
chr11_-_107858777 2.59 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr13_+_33818122 2.56 ENST00000380071.8
RFC3
replication factor C subunit 3
chr11_+_73787853 2.53 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
MRPL48
mitochondrial ribosomal protein L48
chr9_+_78297143 2.51 ENST00000347159.6
PSAT1
phosphoserine aminotransferase 1
chr6_+_158312459 2.51 ENST00000367097.8
TULP4
TUB like protein 4
chr11_-_117316230 2.43 ENST00000313005.11
ENST00000528053.5
BACE1
beta-secretase 1
chr7_+_80646436 2.42 ENST00000419819.2
CD36
CD36 molecule
chr2_-_17800195 2.41 ENST00000402989.5
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr10_-_125816510 2.40 ENST00000650587.1
UROS
uroporphyrinogen III synthase
chr8_-_18684093 2.39 ENST00000428502.6
PSD3
pleckstrin and Sec7 domain containing 3
chr2_-_2324323 2.38 ENST00000648339.1
ENST00000647694.1
MYT1L
myelin transcription factor 1 like
chr7_+_130486324 2.37 ENST00000427521.6
ENST00000378576.9
MEST
mesoderm specific transcript
chr11_-_35360050 2.33 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr11_-_129024157 2.32 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr5_-_69369465 2.31 ENST00000508954.3
ENST00000512152.5
ENST00000503245.5
ENST00000217893.10
ENST00000618980.1
ENST00000502819.5
ENST00000380822.9
ENST00000512561.5
TAF9
AK6
TATA-box binding protein associated factor 9
adenylate kinase 6
chr9_-_101435760 2.29 ENST00000647789.2
ENST00000616752.1
ALDOB
aldolase, fructose-bisphosphate B
chr8_-_104467042 2.27 ENST00000521573.2
ENST00000351513.7
DPYS
dihydropyrimidinase
chr1_-_35718836 2.24 ENST00000270815.5
C1orf216
chromosome 1 open reading frame 216
chr6_-_52994248 2.22 ENST00000457564.1
ENST00000370960.5
GSTA4
glutathione S-transferase alpha 4
chr6_+_63521738 2.19 ENST00000648894.1
ENST00000639568.2
PTP4A1
protein tyrosine phosphatase 4A1
chr4_-_71784046 2.18 ENST00000513476.5
ENST00000273951.13
GC
GC vitamin D binding protein
chr2_-_171894227 2.17 ENST00000422440.7
SLC25A12
solute carrier family 25 member 12
chr4_+_154563003 2.16 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr11_-_3379212 2.13 ENST00000429541.6
ENST00000532539.1
ENST00000343338.11
ENST00000620374.4
ZNF195
zinc finger protein 195
chr12_-_118190510 2.11 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr7_+_130486171 2.07 ENST00000341441.9
ENST00000416162.7
MEST
mesoderm specific transcript
chr4_+_69280472 2.05 ENST00000335568.10
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase family 2 member B28
chr5_-_69369257 2.03 ENST00000509462.5
TAF9
TATA-box binding protein associated factor 9
chr19_+_21082140 1.94 ENST00000616183.1
ENST00000596053.5
ZNF714
zinc finger protein 714
chr3_+_152268920 1.94 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
MBNL1
muscleblind like splicing regulator 1
chr3_+_87227257 1.92 ENST00000471660.5
ENST00000494980.5
ENST00000472024.3
ENST00000263780.9
ENST00000676705.1
CHMP2B
charged multivesicular body protein 2B
chr19_+_21082224 1.92 ENST00000620627.1
ZNF714
zinc finger protein 714
chr8_-_17697654 1.89 ENST00000297488.10
MTUS1
microtubule associated scaffold protein 1
chr3_-_45884685 1.88 ENST00000684620.1
LZTFL1
leucine zipper transcription factor like 1
chr8_+_103021027 1.86 ENST00000518857.5
ENST00000395862.7
ENST00000518738.2
ENST00000521514.5
ATP6V1C1
ATPase H+ transporting V1 subunit C1
chr20_+_58907981 1.85 ENST00000656419.1
GNAS
GNAS complex locus
chr1_+_150067820 1.83 ENST00000419023.3
ENST00000644526.1
VPS45
vacuolar protein sorting 45 homolog
chr5_-_135954962 1.77 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
LECT2
leukocyte cell derived chemotaxin 2
chr17_+_47209338 1.76 ENST00000393450.5
MYL4
myosin light chain 4
chr1_-_63523175 1.74 ENST00000371092.7
ENST00000271002.15
ITGB3BP
integrin subunit beta 3 binding protein
chr11_-_119030848 1.73 ENST00000330775.9
ENST00000357590.9
ENST00000538950.5
ENST00000545985.5
SLC37A4
solute carrier family 37 member 4
chr11_-_3379110 1.71 ENST00000005082.13
ENST00000534569.5
ENST00000438262.6
ENST00000528796.5
ENST00000528410.5
ENST00000529678.5
ENST00000618467.4
ENST00000354599.10
ENST00000399602.9
ENST00000526601.5
ENST00000525502.5
ENST00000533036.5
ZNF195
zinc finger protein 195
chr7_+_111091119 1.69 ENST00000308478.10
LRRN3
leucine rich repeat neuronal 3
chr7_+_111091006 1.65 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr5_-_126595237 1.64 ENST00000637206.1
ENST00000553117.5
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr11_-_6006946 1.64 ENST00000641156.1
ENST00000641835.1
OR56A4
olfactory receptor family 56 subfamily A member 4
chr16_+_56451513 1.64 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
OGFOD1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr11_-_14499833 1.61 ENST00000249923.7
ENST00000529866.5
COPB1
COPI coat complex subunit beta 1
chr2_+_113437691 1.57 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
CBWD2
COBW domain containing 2
chr1_+_47137435 1.56 ENST00000371891.8
ENST00000371890.7
ENST00000619754.4
ENST00000294337.7
ENST00000620131.1
CYP4A22
cytochrome P450 family 4 subfamily A member 22
chr4_-_143905529 1.56 ENST00000358615.9
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr4_-_68349750 1.55 ENST00000579690.5
YTHDC1
YTH domain containing 1
chr20_+_3786772 1.53 ENST00000344256.10
ENST00000379598.9
CDC25B
cell division cycle 25B
chr1_+_147242654 1.52 ENST00000652587.1
ENST00000361293.10
ENST00000369258.8
ENST00000369259.4
ENST00000650714.1
ENST00000639534.1
CHD1L
chromodomain helicase DNA binding protein 1 like
chr12_+_19205294 1.52 ENST00000424268.5
PLEKHA5
pleckstrin homology domain containing A5
chr9_+_65675834 1.51 ENST00000377392.9
ENST00000377384.5
ENST00000430059.6
ENST00000429800.6
ENST00000382405.8
ENST00000377395.8
CBWD5
COBW domain containing 5
chr12_+_122752814 1.51 ENST00000455982.2
ENST00000280557.11
DENR
density regulated re-initiation and release factor
chr14_-_21024092 1.46 ENST00000554398.5
NDRG2
NDRG family member 2
chr2_+_37344594 1.44 ENST00000404976.5
ENST00000338415.8
QPCT
glutaminyl-peptide cyclotransferase
chr12_+_20810698 1.43 ENST00000540853.5
ENST00000381545.8
SLCO1B3
solute carrier organic anion transporter family member 1B3
chr7_-_151520080 1.43 ENST00000496004.5
RHEB
Ras homolog, mTORC1 binding
chr1_+_150067668 1.43 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
VPS45
vacuolar protein sorting 45 homolog
chr8_+_106726012 1.40 ENST00000449762.6
ENST00000297447.10
OXR1
oxidation resistance 1
chr9_+_68241854 1.40 ENST00000616550.4
ENST00000618217.4
ENST00000377342.9
ENST00000478048.5
ENST00000360171.11
CBWD3
COBW domain containing 3
chr18_-_5396265 1.36 ENST00000579951.2
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr16_-_66730216 1.36 ENST00000569320.5
DYNC1LI2
dynein cytoplasmic 1 light intermediate chain 2
chr11_+_22666604 1.35 ENST00000454584.6
GAS2
growth arrest specific 2
chr14_-_21023954 1.35 ENST00000554094.5
NDRG2
NDRG family member 2
chr11_-_14499803 1.35 ENST00000439561.7
ENST00000534234.5
COPB1
COPI coat complex subunit beta 1
chr1_+_171248471 1.31 ENST00000402921.6
ENST00000617670.6
ENST00000367750.7
FMO1
flavin containing dimethylaniline monoxygenase 1
chr18_+_11981548 1.30 ENST00000588927.5
IMPA2
inositol monophosphatase 2
chr3_+_138621225 1.29 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr13_+_35476740 1.28 ENST00000537702.5
NBEA
neurobeachin
chr16_-_12803785 1.25 ENST00000433677.6
ENST00000261660.4
ENST00000381774.9
CPPED1
calcineurin like phosphoesterase domain containing 1
chr2_+_161136901 1.23 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chr1_+_40988513 1.22 ENST00000649215.1
CTPS1
CTP synthase 1
chr9_-_21305313 1.22 ENST00000610521.2
IFNA5
interferon alpha 5
chr12_+_54284258 1.21 ENST00000677666.1
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
chr11_-_75096876 1.17 ENST00000641541.1
ENST00000641593.1
ENST00000641504.1
ENST00000641931.1
ENST00000647690.1
OR2AT4
ENSG00000284722.2
olfactory receptor family 2 subfamily AT member 4
novel transcript
chr10_+_78033760 1.17 ENST00000435275.5
ENST00000613865.5
ENST00000645440.1
ENST00000464716.6
ENST00000360830.9
ENST00000372360.9
ENST00000440692.6
RPS24
ribosomal protein S24
chr2_+_69893940 1.16 ENST00000244227.8
ENST00000409116.5
SNRNP27
small nuclear ribonucleoprotein U4/U6.U5 subunit 27
chr12_-_27014300 1.15 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
TM7SF3
transmembrane 7 superfamily member 3
chrX_+_41334154 1.14 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DDX3X
DEAD-box helicase 3 X-linked
chr2_-_224947030 1.14 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr19_+_9185594 1.14 ENST00000344248.4
OR7D2
olfactory receptor family 7 subfamily D member 2
chr7_-_151519891 1.11 ENST00000262187.10
RHEB
Ras homolog, mTORC1 binding
chr2_+_159733958 1.11 ENST00000409591.5
MARCHF7
membrane associated ring-CH-type finger 7
chr5_-_149063021 1.10 ENST00000515425.6
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr19_+_926001 1.10 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chrY_-_6872608 1.07 ENST00000383036.1
AMELY
amelogenin Y-linked
chrX_+_141880562 1.03 ENST00000443323.2
MAGEC3
MAGE family member C3
chr11_+_72189659 1.02 ENST00000393681.6
FOLR1
folate receptor alpha
chr17_+_70075215 1.01 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr19_-_14884761 1.01 ENST00000642123.1
OR7A17
olfactory receptor family 7 subfamily A member 17
chr9_+_101185029 1.00 ENST00000395056.2
PLPPR1
phospholipid phosphatase related 1
chr12_-_110468222 0.97 ENST00000228827.8
ENST00000537466.6
ENST00000550974.1
GPN3
GPN-loop GTPase 3
chr3_+_138621207 0.96 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr11_+_43311963 0.93 ENST00000534695.5
ENST00000455725.6
ENST00000531273.6
ENST00000420461.6
ENST00000378852.7
ENST00000534600.5
API5
apoptosis inhibitor 5
chr19_-_3500664 0.93 ENST00000427575.6
DOHH
deoxyhypusine hydroxylase
chr7_+_103297425 0.92 ENST00000428154.5
ENST00000249269.9
PMPCB
peptidase, mitochondrial processing subunit beta
chr19_-_3500625 0.91 ENST00000672935.1
DOHH
deoxyhypusine hydroxylase
chr8_-_7582653 0.91 ENST00000648435.1
FAM90A23P
family with sequence similarity 90 member A23, pseudogene
chr6_-_22302826 0.88 ENST00000651245.1
PRL
prolactin
chr2_+_233671879 0.87 ENST00000354728.5
UGT1A9
UDP glucuronosyltransferase family 1 member A9
chr10_+_113854610 0.85 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chrX_-_132219439 0.84 ENST00000370874.2
RAP2C
RAP2C, member of RAS oncogene family
chrX_-_132219473 0.83 ENST00000620646.4
RAP2C
RAP2C, member of RAS oncogene family
chr12_-_21604840 0.82 ENST00000261195.3
GYS2
glycogen synthase 2
chr10_-_113854368 0.82 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr6_+_31655888 0.81 ENST00000375916.4
APOM
apolipoprotein M
chr18_+_12407896 0.80 ENST00000590956.5
ENST00000336990.8
ENST00000440960.6
ENST00000588729.5
PRELID3A
PRELI domain containing 3A
chr1_-_112935984 0.80 ENST00000443580.6
SLC16A1
solute carrier family 16 member 1
chr1_+_66332004 0.80 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
PDE4B
phosphodiesterase 4B
chr5_-_146182475 0.80 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
LARS1
leucyl-tRNA synthetase 1
chr4_+_87608529 0.80 ENST00000651931.1
DSPP
dentin sialophosphoprotein
chr4_+_41613476 0.79 ENST00000508466.1
LIMCH1
LIM and calponin homology domains 1
chr6_-_111483700 0.78 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr16_+_72056153 0.73 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
HP
haptoglobin
chr17_+_57085092 0.71 ENST00000575322.1
ENST00000337714.8
AKAP1
A-kinase anchoring protein 1
chr5_-_146182591 0.70 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
LARS1
leucyl-tRNA synthetase 1
chr11_-_45918789 0.69 ENST00000532681.5
PEX16
peroxisomal biogenesis factor 16
chr8_-_30812867 0.68 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr6_-_26189101 0.68 ENST00000614247.2
H4C4
H4 clustered histone 4
chr19_+_21082190 0.67 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
ZNF714
zinc finger protein 714
chr8_-_17722217 0.65 ENST00000381861.7
MTUS1
microtubule associated scaffold protein 1
chr12_+_123633739 0.64 ENST00000618160.4
GTF2H3
general transcription factor IIH subunit 3
chr2_+_161160420 0.64 ENST00000392749.7
ENST00000405852.5
TANK
TRAF family member associated NFKB activator
chr12_-_103841210 0.63 ENST00000392876.8
NT5DC3
5'-nucleotidase domain containing 3
chr8_+_7730739 0.63 ENST00000648174.1
FAM90A16P
family with sequence similarity 90 member A16, pseudogene
chr15_-_55249029 0.63 ENST00000566877.5
RAB27A
RAB27A, member RAS oncogene family
chr11_+_72189528 0.62 ENST00000312293.9
FOLR1
folate receptor alpha
chr9_+_128787331 0.60 ENST00000223865.8
TBC1D13
TBC1 domain family member 13
chr1_+_16043776 0.59 ENST00000375679.9
CLCNKB
chloride voltage-gated channel Kb
chr17_+_70075317 0.59 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr19_+_42325612 0.59 ENST00000251268.11
MEGF8
multiple EGF like domains 8
chrX_-_41665766 0.58 ENST00000643043.2
ENST00000486402.1
ENST00000646087.2
CASK
calcium/calmodulin dependent serine protein kinase
chr15_+_43133546 0.58 ENST00000260403.7
TMEM62
transmembrane protein 62
chr19_-_35812838 0.58 ENST00000653904.2
PRODH2
proline dehydrogenase 2
chr16_+_28494634 0.58 ENST00000564831.6
ENST00000431282.2
APOBR
apolipoprotein B receptor
chr12_-_123633604 0.58 ENST00000534960.5
ENST00000424014.7
EIF2B1
eukaryotic translation initiation factor 2B subunit alpha
chr7_-_44082464 0.57 ENST00000335195.10
ENST00000395831.7
ENST00000414235.5
ENST00000242248.10
ENST00000452049.1
POLM
DNA polymerase mu
chr8_-_7575006 0.57 ENST00000648590.1
FAM90A22P
family with sequence similarity 90 member A22, pseudogene
chr8_-_118951876 0.55 ENST00000297350.9
TNFRSF11B
TNF receptor superfamily member 11b
chr8_+_7768977 0.54 ENST00000533716.2
FAM90A10P
family with sequence similarity 90 member A10, pseudogene
chr1_-_226739271 0.53 ENST00000429204.6
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr3_+_158110052 0.53 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
RSRC1
arginine and serine rich coiled-coil 1
chr18_-_21703688 0.53 ENST00000584464.1
ENST00000578270.5
ABHD3
abhydrolase domain containing 3, phospholipase
chr19_-_6416773 0.53 ENST00000595223.5
KHSRP
KH-type splicing regulatory protein
chr6_+_111087495 0.52 ENST00000612036.4
ENST00000368851.10
SLC16A10
solute carrier family 16 member 10
chr10_-_72088533 0.51 ENST00000373109.7
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr2_+_209579429 0.50 ENST00000361559.8
MAP2
microtubule associated protein 2
chr6_-_109381739 0.48 ENST00000504373.2
CD164
CD164 molecule
chr5_+_175861628 0.48 ENST00000509837.5
CPLX2
complexin 2
chr2_-_70248454 0.47 ENST00000416149.6
ENST00000282574.8
TIA1
TIA1 cytotoxic granule associated RNA binding protein
chr2_+_233617626 0.46 ENST00000373450.5
UGT1A8
UDP glucuronosyltransferase family 1 member A8
chr2_-_208146150 0.46 ENST00000260988.5
CRYGB
crystallin gamma B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0009786 regulation of asymmetric cell division(GO:0009786)
1.6 6.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.4 5.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
1.1 6.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.9 5.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.8 2.5 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.8 3.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.8 2.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859)
0.7 2.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 1.9 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.6 5.3 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 2.9 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.5 1.6 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.5 1.6 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.5 2.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 5.1 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 5.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 3.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 4.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 1.5 GO:0002188 translation reinitiation(GO:0002188)
0.4 7.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4 1.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.4 2.8 GO:0014038 regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
0.3 3.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 1.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 4.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 1.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.3 2.9 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 1.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 1.6 GO:0006449 regulation of translational termination(GO:0006449)
0.3 2.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 1.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.7 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 1.9 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 1.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 1.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.2 3.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.8 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 2.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 1.2 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.2 2.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 2.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.3 GO:0051552 flavone metabolic process(GO:0051552)
0.2 5.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.7 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 2.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.8 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 2.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 1.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 1.5 GO:0007144 female meiosis I(GO:0007144)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 5.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.6 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.5 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 4.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 2.2 GO:0044320 cellular response to leptin stimulus(GO:0044320)
0.1 3.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:2000397 ubiquitin-dependent endocytosis(GO:0070086) positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 1.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 1.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 1.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 2.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 3.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 2.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.2 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.5 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.5 GO:0035726 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 3.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.8 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 3.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.9 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 2.2 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 1.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 2.5 GO:0061512 protein localization to cilium(GO:0061512)
0.1 2.1 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 3.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 6.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 1.0 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 1.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 2.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 6.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 1.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.8 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 2.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 2.3 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 2.8 GO:0007498 mesoderm development(GO:0007498)
0.0 2.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 4.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.1 GO:0051563 astrocyte activation involved in immune response(GO:0002265) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.9 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0033198 response to ATP(GO:0033198)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.6 GO:0036449 microtubule minus-end(GO:0036449) meiotic spindle(GO:0072687)
0.8 2.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.7 7.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 2.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.6 3.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.6 2.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.6 2.9 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.5 4.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.5 3.2 GO:0032437 cuticular plate(GO:0032437)
0.5 1.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4 2.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 3.5 GO:0070852 cell body fiber(GO:0070852)
0.3 6.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 3.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 0.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 5.5 GO:0035371 microtubule plus-end(GO:0035371)
0.2 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.2 3.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.2 0.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 0.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.2 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 5.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 5.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.7 GO:0031045 dense core granule(GO:0031045)
0.1 7.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 6.4 GO:0005771 multivesicular body(GO:0005771)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 5.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0033503 HULC complex(GO:0033503)
0.1 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 4.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0031672 A band(GO:0031672)
0.0 5.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 1.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0031904 endosome lumen(GO:0031904)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.8 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.6 GO:0005770 late endosome(GO:0005770)
0.0 17.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.6 GO:0045121 membrane raft(GO:0045121)
0.0 1.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.2 GO:0043209 myelin sheath(GO:0043209)
0.0 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 5.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0005865 striated muscle thin filament(GO:0005865)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.4 5.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.8 7.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.8 2.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.7 2.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.7 5.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 1.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.6 2.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.5 7.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 1.7 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 1.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.4 14.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 2.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 6.5 GO:0008242 omega peptidase activity(GO:0008242)
0.3 1.6 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.3 4.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 1.2 GO:0003883 CTP synthase activity(GO:0003883)
0.3 5.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 1.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.3 1.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.3 1.1 GO:0043273 CTPase activity(GO:0043273)
0.3 1.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.3 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 2.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 6.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.8 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 2.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 1.3 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 4.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 3.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 3.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 5.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.5 GO:0070628 proteasome binding(GO:0070628)
0.1 1.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 1.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 1.6 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 3.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.4 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.7 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.8 GO:0005549 odorant binding(GO:0005549)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.1 2.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.5 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 1.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 4.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 3.7 GO:0019003 GDP binding(GO:0019003)
0.0 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 8.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 4.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 6.1 GO:0008017 microtubule binding(GO:0008017)
0.0 2.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 4.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 2.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 3.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 3.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 9.4 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.8 GO:0016209 antioxidant activity(GO:0016209)
0.0 5.6 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 10.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 8.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.9 PID MYC PATHWAY C-MYC pathway
0.1 2.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 2.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 5.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 2.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.7 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 6.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 8.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 9.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 6.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 5.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 5.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 4.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 5.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis