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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXD11_HOXA11

Z-value: 3.98

Motif logo

Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
ENSG00000128713.14 HOXD11
ENSG00000005073.6 HOXA11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA11hg38_v1_chr7_-_27185223_27185249-0.282.9e-05Click!
HOXD11hg38_v1_chr2_+_176107272_176107297-0.194.4e-03Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_55407719 10.99 ENST00000587845.5
ENST00000589978.1
ENST00000264552.14
ubiquitin conjugating enzyme E2 S
chr8_-_103501890 9.80 ENST00000649416.1
novel protein
chr14_+_55611977 9.74 ENST00000395309.7
ENST00000413890.6
kinectin 1
chr7_+_80133830 9.45 ENST00000648098.1
ENST00000648476.1
ENST00000648412.1
ENST00000648953.1
ENST00000648306.1
ENST00000648832.1
ENST00000648877.1
ENST00000442586.2
ENST00000649487.1
ENST00000649267.1
G protein subunit alpha i1
chr2_-_206159509 9.17 ENST00000423725.5
NADH:ubiquinone oxidoreductase core subunit S1
chr7_+_73692596 9.08 ENST00000453316.1
BUD23 rRNA methyltransferase and ribosome maturation factor
chr15_+_66505289 8.99 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr2_-_216013582 8.95 ENST00000620139.4
melanoregulin
chr16_+_14937443 8.95 ENST00000328085.10
nuclear pore complex interacting protein family member A1
chr15_+_66504959 8.66 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr2_-_206159194 8.59 ENST00000455934.6
ENST00000449699.5
ENST00000454195.1
NADH:ubiquinone oxidoreductase core subunit S1
chr11_-_47426419 7.74 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr12_+_6724008 7.71 ENST00000626119.2
ENST00000543155.6
COP9 signalosome subunit 7A
chr12_+_6724071 7.70 ENST00000229251.7
ENST00000539735.5
ENST00000538410.5
COP9 signalosome subunit 7A
chr12_+_6724271 7.28 ENST00000534947.5
ENST00000541866.5
ENST00000534877.5
ENST00000538753.5
COP9 signalosome subunit 7A
chr18_+_58341038 7.04 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr2_-_189179754 6.92 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr1_+_51617079 6.80 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
oxysterol binding protein like 9
chr8_-_27837765 6.78 ENST00000521226.2
ENST00000301905.9
PDZ binding kinase
chr14_+_73097027 6.45 ENST00000532192.1
RNA binding motif protein 25
chr2_+_108588453 6.40 ENST00000393310.5
LIM zinc finger domain containing 1
chr10_+_92593112 6.01 ENST00000260731.5
kinesin family member 11
chr3_+_158110052 5.90 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
arginine and serine rich coiled-coil 1
chr11_-_47426216 5.89 ENST00000530651.5
ENST00000524447.6
ENST00000531051.6
ENST00000526993.1
ENST00000602866.5
proteasome 26S subunit, ATPase 3
chr6_-_8102481 5.70 ENST00000502429.5
ENST00000429723.6
ENST00000379715.10
ENST00000507463.1
eukaryotic translation elongation factor 1 epsilon 1
chr2_-_206159410 5.69 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NADH:ubiquinone oxidoreductase core subunit S1
chr11_-_11353241 5.65 ENST00000528848.3
casein kinase 2 alpha 3
chrX_-_136880715 5.54 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr16_+_22490337 5.50 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chr12_+_49227874 5.47 ENST00000541364.5
tubulin alpha 1c
chr1_+_84164962 5.43 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr18_-_77017042 5.25 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
myelin basic protein
chr12_-_56741535 5.22 ENST00000647707.1
novel protein
chr1_-_6360677 5.15 ENST00000377845.7
acyl-CoA thioesterase 7
chr2_-_175181663 5.13 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP synthase membrane subunit c locus 3
chr13_+_52455972 4.86 ENST00000490903.5
ENST00000480747.1
cytoskeleton associated protein 2
chr12_-_89656051 4.78 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr1_+_119711884 4.75 ENST00000641947.1
ENST00000641074.1
ENST00000641115.1
ENST00000369409.9
ENST00000641023.2
ENST00000641272.1
phosphoglycerate dehydrogenase
chrX_-_13817027 4.69 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr3_-_197226351 4.69 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr6_+_158312459 4.69 ENST00000367097.8
TUB like protein 4
chr1_-_114581589 4.56 ENST00000369541.4
BCAS2 pre-mRNA processing factor
chr8_+_26293112 4.56 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr12_-_89656093 4.54 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr20_+_3786772 4.50 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr11_-_796185 4.49 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr6_-_17706748 4.46 ENST00000613258.4
ENST00000537253.5
nucleoporin 153
chr3_-_146528750 4.46 ENST00000483300.5
phospholipid scramblase 1
chr3_-_79767987 4.46 ENST00000464233.6
roundabout guidance receptor 1
chr12_-_47705971 4.34 ENST00000380650.4
RNA polymerase II associated protein 3
chr6_-_38703066 4.33 ENST00000373365.5
glyoxalase I
chrX_-_37847562 4.22 ENST00000378578.9
dynein light chain Tctex-type 3
chr1_+_23019415 4.16 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
lysine demethylase 1A
chr3_+_158110363 4.16 ENST00000683137.1
arginine and serine rich coiled-coil 1
chr8_+_11809135 4.01 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr16_-_15378294 3.98 ENST00000360151.9
ENST00000543801.5
nuclear pore complex interacting protein family member A5
chr8_+_106726012 3.89 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr12_-_47705990 3.86 ENST00000432584.7
ENST00000005386.8
RNA polymerase II associated protein 3
chr20_+_37777262 3.76 ENST00000373469.1
catenin beta like 1
chr11_-_14499833 3.76 ENST00000249923.7
ENST00000529866.5
COPI coat complex subunit beta 1
chr6_+_63521738 3.75 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr10_+_119819244 3.72 ENST00000637174.1
inositol polyphosphate-5-phosphatase F
chr14_+_52707178 3.66 ENST00000612399.4
proteasome 26S subunit, ATPase 6
chr6_-_17706852 3.64 ENST00000262077.3
nucleoporin 153
chr6_+_80004615 3.60 ENST00000369798.7
ENST00000502580.5
ENST00000511260.5
TTK protein kinase
chr3_-_49029378 3.54 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr7_+_55365317 3.54 ENST00000254770.3
LanC like 2
chr6_-_131000722 3.53 ENST00000528282.5
erythrocyte membrane protein band 4.1 like 2
chr11_-_31810991 3.53 ENST00000640684.1
paired box 6
chr3_+_138621225 3.53 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr3_+_130850585 3.48 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr18_-_36798482 3.44 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr1_+_81306096 3.40 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr2_+_108588286 3.40 ENST00000332345.10
LIM zinc finger domain containing 1
chr2_+_137964279 3.36 ENST00000329366.8
histamine N-methyltransferase
chr12_+_54284258 3.35 ENST00000677666.1
heterogeneous nuclear ribonucleoprotein A1
chr18_+_58196736 3.32 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr4_+_83035159 3.32 ENST00000509317.5
ENST00000264389.7
ENST00000503682.5
ENST00000511653.1
COP9 signalosome subunit 4
chr1_+_67685170 3.32 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr12_-_30735014 3.30 ENST00000433722.6
caprin family member 2
chr3_-_15797930 3.24 ENST00000683139.1
ankyrin repeat domain 28
chr3_-_37174578 3.23 ENST00000336686.9
LRR binding FLII interacting protein 2
chr10_+_78033760 3.20 ENST00000435275.5
ENST00000613865.5
ENST00000645440.1
ENST00000464716.6
ENST00000360830.9
ENST00000372360.9
ENST00000440692.6
ribosomal protein S24
chr3_-_98523013 3.19 ENST00000394181.6
ENST00000508902.5
ENST00000394180.6
claudin domain containing 1
chr13_+_52455429 3.18 ENST00000468284.1
ENST00000378034.7
ENST00000378037.9
ENST00000258607.10
cytoskeleton associated protein 2
chr5_+_136160986 3.12 ENST00000507637.1
SMAD family member 5
chr9_+_12693327 3.11 ENST00000388918.10
tyrosinase related protein 1
chr18_+_58255433 3.09 ENST00000635997.1
NEDD4 like E3 ubiquitin protein ligase
chr9_+_104094557 3.05 ENST00000374787.7
structural maintenance of chromosomes 2
chr11_-_62706234 3.03 ENST00000403550.5
BSCL2 lipid droplet biogenesis associated, seipin
chr3_-_98522514 3.03 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr11_-_107858777 2.99 ENST00000525815.6
solute carrier family 35 member F2
chr15_-_55196899 2.98 ENST00000677147.1
ENST00000260443.9
ENST00000677730.1
ribosomal L24 domain containing 1
chr1_+_171557845 2.97 ENST00000644916.1
proline rich coiled-coil 2C
chr1_+_38012706 2.95 ENST00000373014.5
UTP11 small subunit processome component
chr4_+_169660062 2.93 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chr3_-_15798184 2.93 ENST00000624145.3
ankyrin repeat domain 28
chrX_-_23743201 2.92 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
acyl-CoA thioesterase 9
chr19_+_36100593 2.91 ENST00000680211.1
WD repeat domain 62
chr1_+_224356852 2.91 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr15_+_84981834 2.88 ENST00000394553.6
phosphodiesterase 8A
chr17_+_50746614 2.87 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr18_-_24311495 2.84 ENST00000357041.8
oxysterol binding protein like 1A
chr4_+_56977710 2.82 ENST00000450656.5
ENST00000381227.5
RNA polymerase II subunit B
chr1_+_236795254 2.81 ENST00000366577.10
ENST00000674797.2
5-methyltetrahydrofolate-homocysteine methyltransferase
chr3_+_157436842 2.81 ENST00000295927.4
pentraxin 3
chr17_+_17179527 2.77 ENST00000579361.1
myosin phosphatase Rho interacting protein
chrX_+_77899440 2.77 ENST00000373335.4
ENST00000475465.1
ENST00000650309.2
ENST00000647835.1
cytochrome c oxidase subunit 7B
chr6_-_89638716 2.77 ENST00000626778.2
ENST00000520441.5
ENST00000523377.2
ENST00000520318.1
LYR motif containing 2
chr8_+_109334317 2.76 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2 transcription and export complex 2 subunit
chr11_-_31811112 2.75 ENST00000640242.1
ENST00000640613.1
ENST00000606377.7
paired box 6
chr3_-_123991352 2.75 ENST00000184183.8
rhophilin associated tail protein 1
chr1_-_151763334 2.74 ENST00000481777.5
ENST00000368829.3
ENST00000368830.8
mitochondrial ribosomal protein L9
chr8_-_65634138 2.73 ENST00000518908.5
ENST00000276569.8
ENST00000519352.1
armadillo repeat containing 1
chr7_+_134779663 2.72 ENST00000361901.6
caldesmon 1
chr3_+_138621207 2.72 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr12_-_100092890 2.70 ENST00000550544.5
ENST00000551980.1
ENST00000548045.5
ENST00000545232.6
ENST00000551973.5
UHRF1 binding protein 1 like
chr2_-_216013517 2.69 ENST00000263268.11
melanoregulin
chr7_+_134779625 2.69 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr1_-_100894818 2.69 ENST00000370114.8
exostosin like glycosyltransferase 2
chr12_+_19205294 2.68 ENST00000424268.5
pleckstrin homology domain containing A5
chr8_-_65634202 2.65 ENST00000458464.3
armadillo repeat containing 1
chr1_-_100894775 2.65 ENST00000416479.1
ENST00000370113.7
exostosin like glycosyltransferase 2
chr7_+_141551278 2.64 ENST00000629555.2
ENST00000473247.5
ENST00000648690.1
ENST00000649286.2
ENST00000649914.1
ENST00000648395.1
ENST00000648068.1
ENST00000650547.1
acylglycerol kinase
chr17_+_68525795 2.62 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr11_-_31811140 2.62 ENST00000639916.1
paired box 6
chr5_-_131165272 2.62 ENST00000675491.1
ENST00000506908.2
histidine triad nucleotide binding protein 1
chr1_-_53238485 2.59 ENST00000371466.4
ENST00000371470.8
mago homolog, exon junction complex subunit
chr17_-_58353069 2.59 ENST00000580947.1
SPT4 homolog, DSIF elongation factor subunit
chrX_-_103688090 2.59 ENST00000433176.6
mortality factor 4 like 2
chr8_+_26577843 2.57 ENST00000311151.9
dihydropyrimidinase like 2
chr14_-_22929356 2.56 ENST00000397440.8
ENST00000627278.1
ENST00000421938.2
ENST00000324366.13
ENST00000554867.5
ENST00000556616.5
ENST00000216350.12
ENST00000553550.5
ENST00000397441.6
ENST00000553897.5
protein arginine methyltransferase 5
chr11_-_31806886 2.56 ENST00000640963.1
paired box 6
chr9_-_14300231 2.55 ENST00000636735.1
nuclear factor I B
chr6_-_99394164 2.55 ENST00000254759.8
coenzyme Q3, methyltransferase
chr1_-_31919093 2.55 ENST00000602683.5
ENST00000470404.5
protein tyrosine phosphatase 4A2
chr11_-_62706304 2.54 ENST00000278893.11
ENST00000407022.7
ENST00000421906.5
BSCL2 lipid droplet biogenesis associated, seipin
chr15_-_55196608 2.52 ENST00000677989.1
ENST00000562895.2
ENST00000569386.2
ribosomal L24 domain containing 1
chr12_-_123272234 2.52 ENST00000544658.5
cyclin dependent kinase 2 associated protein 1
chr9_-_83978429 2.47 ENST00000351839.7
heterogeneous nuclear ribonucleoprotein K
chr19_+_40775154 2.40 ENST00000594436.5
ENST00000597784.5
MIA SH3 domain containing
chr13_-_31161927 2.40 ENST00000380405.7
heat shock protein family H (Hsp110) member 1
chr12_-_10909562 2.38 ENST00000390677.2
taste 2 receptor member 13
chr1_+_220094086 2.38 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chrX_+_11111291 2.38 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
holocytochrome c synthase
chr16_+_14711689 2.33 ENST00000552140.5
nuclear pore complex interacting protein family member A3
chr1_+_155308748 2.32 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
farnesyl diphosphate synthase
chr3_+_23810436 2.30 ENST00000467766.5
ENST00000424381.5
ubiquitin conjugating enzyme E2 E1
chr11_-_31811034 2.30 ENST00000638250.1
paired box 6
chr7_-_64563063 2.28 ENST00000309683.11
zinc finger protein 680
chr16_-_66730216 2.27 ENST00000569320.5
dynein cytoplasmic 1 light intermediate chain 2
chr2_+_186590022 2.26 ENST00000261023.8
ENST00000374907.7
integrin subunit alpha V
chr17_-_42136431 2.25 ENST00000552162.5
ENST00000550504.5
RAB5C, member RAS oncogene family
chr5_-_74641419 2.25 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr11_-_31811231 2.25 ENST00000438681.6
paired box 6
chr5_-_88785493 2.24 ENST00000503554.4
myocyte enhancer factor 2C
chr11_+_27040725 2.24 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr12_-_62935117 2.22 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr2_+_63842325 2.21 ENST00000445915.6
ENST00000475462.5
UDP-glucose pyrophosphorylase 2
chr1_-_21050952 2.20 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr7_+_100884974 2.20 ENST00000448764.5
serrate, RNA effector molecule
chr1_-_155910881 2.19 ENST00000609492.1
ENST00000368322.7
Ras like without CAAX 1
chr5_-_176388563 2.18 ENST00000509257.1
ENST00000616685.1
ENST00000614830.5
NOP16 nucleolar protein
chr15_-_55249029 2.14 ENST00000566877.5
RAB27A, member RAS oncogene family
chr2_+_37344594 2.13 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr16_+_16379055 2.13 ENST00000530217.2
nuclear pore complex interacting protein family member A7
chr6_+_30720335 2.11 ENST00000327892.13
tubulin beta class I
chr1_+_75724431 2.10 ENST00000541113.6
ENST00000680805.1
acyl-CoA dehydrogenase medium chain
chr5_+_72848161 2.10 ENST00000506351.6
transportin 1
chr2_-_190250503 2.09 ENST00000409820.2
ENST00000410045.5
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_48924559 2.09 ENST00000650262.1
cell division cycle 14C
chr11_-_14499803 2.08 ENST00000439561.7
ENST00000534234.5
COPI coat complex subunit beta 1
chr11_+_27041313 2.06 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr12_+_20810698 2.05 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr7_-_41703062 2.03 ENST00000242208.5
inhibin subunit beta A
chr12_-_55296569 2.02 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr8_-_89984231 2.02 ENST00000517337.1
ENST00000409330.5
nibrin
chr6_+_63571702 1.99 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr11_+_9575496 1.98 ENST00000681684.1
WEE1 G2 checkpoint kinase
chr2_+_63841882 1.98 ENST00000337130.10
ENST00000488245.6
UDP-glucose pyrophosphorylase 2
chr14_-_59630806 1.97 ENST00000342503.8
reticulon 1
chr19_+_40775511 1.97 ENST00000263369.4
ENST00000597140.5
MIA SH3 domain containing
chr6_+_12290353 1.95 ENST00000379375.6
endothelin 1
chr1_+_44405164 1.92 ENST00000355387.6
ring finger protein 220
chr11_+_102112445 1.92 ENST00000524575.5
Yes1 associated transcriptional regulator
chr10_-_114684612 1.92 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr4_-_173399102 1.91 ENST00000296506.8
stimulator of chondrogenesis 1
chr11_-_31810657 1.91 ENST00000379109.7
paired box 6
chr3_+_173398438 1.88 ENST00000457714.5
neuroligin 1
chr3_+_87227257 1.88 ENST00000471660.5
ENST00000494980.5
ENST00000472024.3
ENST00000263780.9
ENST00000676705.1
charged multivesicular body protein 2B
chr8_-_116874746 1.87 ENST00000297338.7
RAD21 cohesin complex component
chr10_+_113709261 1.87 ENST00000672138.1
ENST00000452490.3
caspase 7
chr12_-_46372763 1.86 ENST00000256689.10
solute carrier family 38 member 2
chr2_-_74392025 1.86 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr3_-_165837412 1.86 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr7_+_116862552 1.85 ENST00000361183.8
ENST00000639546.1
ENST00000490693.5
capping actin protein of muscle Z-line subunit alpha 2
chr18_+_58044343 1.84 ENST00000356462.10
ENST00000589054.5
ENST00000617539.1
ENST00000676024.1
ENST00000382850.8
ENST00000256830.13
NEDD4 like E3 ubiquitin protein ligase
chr1_-_93681829 1.83 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr3_-_27456743 1.82 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr20_+_36091409 1.82 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
2.7 11.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.7 8.1 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
1.7 26.0 GO:0000338 protein deneddylation(GO:0000338)
1.6 4.7 GO:0006566 threonine metabolic process(GO:0006566)
1.6 9.3 GO:1990034 calcium ion export from cell(GO:1990034)
1.4 6.9 GO:2000542 negative regulation of gastrulation(GO:2000542)
1.4 16.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.3 5.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.2 3.6 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.2 3.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
1.1 19.3 GO:0003322 pancreatic A cell development(GO:0003322)
1.1 4.5 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.1 5.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.1 5.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.1 5.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.0 4.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.9 2.8 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.9 3.7 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.9 5.4 GO:0097338 response to clozapine(GO:0097338)
0.8 16.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.8 4.6 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.8 3.8 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.8 2.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.7 2.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.7 4.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.7 3.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.7 9.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.7 2.1 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.7 4.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.7 2.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.7 4.0 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.7 3.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.7 2.0 GO:0030185 nitric oxide transport(GO:0030185)
0.6 2.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.6 3.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.6 1.9 GO:0014016 neuroblast differentiation(GO:0014016)
0.6 2.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.6 1.8 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6 3.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.6 4.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.6 3.3 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.6 3.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.5 2.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 3.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.5 3.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.5 3.0 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.5 1.5 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.5 2.4 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.5 2.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.5 2.3 GO:0045338 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.5 1.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 1.3 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.4 3.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.4 2.1 GO:0006574 valine catabolic process(GO:0006574)
0.4 13.5 GO:0032402 melanosome transport(GO:0032402)
0.4 4.5 GO:0007144 female meiosis I(GO:0007144)
0.4 5.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 23.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 1.6 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.4 4.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 3.1 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.4 4.1 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.5 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.4 1.8 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.3 1.6 GO:1901419 regulation of response to alcohol(GO:1901419)
0.3 4.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3 1.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 6.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 9.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 2.2 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.3 3.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 1.9 GO:0032328 alanine transport(GO:0032328)
0.3 22.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.3 2.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.3 1.6 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 1.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 3.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 6.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 2.4 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.7 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 1.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 2.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 3.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.8 GO:0010265 SCF complex assembly(GO:0010265)
0.2 4.4 GO:0034389 lipid particle organization(GO:0034389)
0.2 4.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 1.9 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.2 2.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 1.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.2 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 1.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 4.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 2.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 5.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 3.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 8.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.2 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 1.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.2 2.2 GO:0031053 primary miRNA processing(GO:0031053)
0.2 0.5 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 1.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 2.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 1.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 1.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 0.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 0.9 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.7 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 3.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 2.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.0 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 2.6 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 2.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 8.0 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 0.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 5.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 0.4 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 2.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 3.7 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.4 GO:0070989 oxidative demethylation(GO:0070989)
0.1 1.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 2.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 20.2 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 8.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 9.7 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.3 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 2.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 1.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.0 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.1 1.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 3.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.7 GO:0061512 protein localization to cilium(GO:0061512)
0.1 2.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 14.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 2.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 8.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.2 GO:0060003 copper ion export(GO:0060003)
0.1 0.3 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.8 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.9 GO:0007099 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.1 2.7 GO:0007031 peroxisome organization(GO:0007031)
0.1 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.9 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 1.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 3.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 3.5 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.4 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 6.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 1.5 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 1.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 1.0 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 1.6 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.9 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.9 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 2.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 4.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.6 GO:0006833 water transport(GO:0006833)
0.0 5.3 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.1 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 2.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 2.4 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 1.0 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
4.4 17.7 GO:1990423 RZZ complex(GO:1990423)
2.3 6.9 GO:0005588 collagen type V trimer(GO:0005588)
1.7 17.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.9 5.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.9 5.3 GO:0033269 internode region of axon(GO:0033269)
0.8 8.2 GO:0097255 R2TP complex(GO:0097255)
0.8 5.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.8 2.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.7 2.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.7 2.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.6 1.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.6 11.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.6 30.6 GO:0008180 COP9 signalosome(GO:0008180)
0.5 2.6 GO:0032044 DSIF complex(GO:0032044)
0.5 5.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 1.9 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 9.8 GO:0000974 Prp19 complex(GO:0000974)
0.4 2.2 GO:0001651 dense fibrillar component(GO:0001651)
0.4 9.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 6.1 GO:0030478 actin cap(GO:0030478)
0.4 8.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 3.0 GO:0000796 condensin complex(GO:0000796)
0.4 11.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 1.8 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.3 6.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 1.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 6.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 5.0 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.3 1.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 1.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 1.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 16.4 GO:0005771 multivesicular body(GO:0005771)
0.2 0.9 GO:0035363 histone locus body(GO:0035363)
0.2 10.8 GO:0099738 cell cortex region(GO:0099738)
0.2 1.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 4.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 2.8 GO:0000124 SAGA complex(GO:0000124)
0.2 4.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.6 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2 2.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.8 GO:0070852 cell body fiber(GO:0070852)
0.2 2.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.2 2.8 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 0.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.2 2.9 GO:0005682 U5 snRNP(GO:0005682)
0.2 2.6 GO:0034709 methylosome(GO:0034709)
0.2 1.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 0.9 GO:0000125 PCAF complex(GO:0000125)
0.2 1.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 1.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 6.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.7 GO:0071141 SMAD protein complex(GO:0071141)
0.1 7.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.2 GO:0097433 dense body(GO:0097433)
0.1 14.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 2.9 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 9.3 GO:0005643 nuclear pore(GO:0005643)
0.1 3.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.2 GO:0000145 exocyst(GO:0000145)
0.1 2.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 4.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.4 GO:0045252 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 5.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0036128 CatSper complex(GO:0036128)
0.1 2.3 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.5 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 12.2 GO:0005819 spindle(GO:0005819)
0.0 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 10.9 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 18.3 GO:0016607 nuclear speck(GO:0016607)
0.0 6.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 3.5 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 7.8 GO:0005925 focal adhesion(GO:0005925)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 4.2 GO:0000785 chromatin(GO:0000785)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 10.2 GO:0005730 nucleolus(GO:0005730)
0.0 5.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 17.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.9 7.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.8 5.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
1.6 4.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.5 9.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
1.5 4.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.1 22.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.1 3.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
1.0 4.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.9 4.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.9 16.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.9 3.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.9 2.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.9 2.6 GO:0008169 C-methyltransferase activity(GO:0008169)
0.9 3.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.7 2.2 GO:0034512 box C/D snoRNA binding(GO:0034512)
0.7 2.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.7 2.9 GO:0033265 choline binding(GO:0033265)
0.7 2.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.7 2.1 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.7 4.0 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.6 2.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.6 9.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.6 5.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.6 2.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 4.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 3.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.5 5.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.5 2.8 GO:0001849 complement component C1q binding(GO:0001849)
0.5 2.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.5 5.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.5 2.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 1.3 GO:0002135 CTP binding(GO:0002135)
0.4 12.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 5.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 5.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 1.2 GO:0055100 adiponectin binding(GO:0055100)
0.4 2.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 3.2 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.4 3.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 3.5 GO:0042731 PH domain binding(GO:0042731)
0.4 7.4 GO:0043495 protein anchor(GO:0043495)
0.3 5.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 2.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 2.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 19.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 0.9 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.3 1.5 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.3 4.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 2.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.3 4.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 9.6 GO:0015248 sterol transporter activity(GO:0015248)
0.3 1.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 2.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 2.6 GO:0001727 lipid kinase activity(GO:0001727)
0.3 0.8 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 11.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 4.7 GO:0097016 L27 domain binding(GO:0097016)
0.3 2.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 1.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 6.1 GO:0005523 tropomyosin binding(GO:0005523)
0.2 6.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 2.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 1.6 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 2.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 0.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 0.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 2.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 4.6 GO:0048156 tau protein binding(GO:0048156)
0.2 1.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 9.9 GO:0019894 kinesin binding(GO:0019894)
0.2 2.2 GO:0047617 CoA hydrolase activity(GO:0016289) acyl-CoA hydrolase activity(GO:0047617)
0.2 2.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 1.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 7.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 6.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 3.3 GO:0031489 myosin V binding(GO:0031489)
0.1 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 2.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 2.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.6 GO:1903136 cuprous ion binding(GO:1903136)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 3.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 3.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 5.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0070492 sialic acid binding(GO:0033691) oligosaccharide binding(GO:0070492)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 8.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 12.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 2.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.6 GO:0046332 SMAD binding(GO:0046332)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 8.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 4.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 9.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 8.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 25.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 6.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 3.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 10.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 17.4 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 3.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.2 PID ATM PATHWAY ATM pathway
0.1 6.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 6.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.0 ST ADRENERGIC Adrenergic Pathway
0.1 1.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 5.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 2.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 4.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.5 19.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5 5.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.5 9.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.4 8.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 27.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 10.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 3.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 6.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 6.0 REACTOME KINESINS Genes involved in Kinesins
0.2 15.8 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.2 6.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 1.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.2 5.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 1.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 4.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 4.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 4.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 4.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 2.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 6.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 15.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 2.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 4.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 3.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 2.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 4.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 4.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 12.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 6.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 6.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 12.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 2.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 2.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 4.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.6 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling