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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HSFY2

Z-value: 8.07

Motif logo

Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
ENSG00000169953.12 HSFY2

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_+_31739260 29.62 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor
chr2_-_168913277 27.76 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr3_-_185923893 26.71 ENST00000259043.11
transformer 2 beta homolog
chr1_-_150234668 26.20 ENST00000616917.4
acidic nuclear phosphoprotein 32 family member E
chr1_-_197146620 25.10 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr1_-_197146688 24.99 ENST00000294732.11
assembly factor for spindle microtubules
chr15_+_41286011 24.88 ENST00000661438.1
novel protein
chr4_-_99950262 22.78 ENST00000296417.6
ENST00000651623.1
H2A.Z variant histone 1
chr21_-_39349048 22.69 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chr2_+_27212866 21.94 ENST00000419744.1
all-trans retinoic acid induced differentiation factor
chrX_+_49171918 21.16 ENST00000376322.7
proteolipid protein 2
chr2_+_200305873 20.85 ENST00000439084.5
ENST00000409718.5
spermatogenesis associated serine rich 2 like
chr2_+_38778194 20.85 ENST00000409566.1
ENST00000281950.8
gem nuclear organelle associated protein 6
chrX_+_155881306 20.73 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chr3_-_52535006 20.56 ENST00000307076.8
5'-nucleotidase domain containing 2
chr14_+_20455210 20.48 ENST00000557344.5
ENST00000216714.8
ENST00000398030.8
ENST00000557181.5
ENST00000555839.5
ENST00000553368.1
ENST00000556054.5
ENST00000557054.1
ENST00000557592.5
ENST00000557150.5
apurinic/apyrimidinic endodeoxyribonuclease 1
chr7_+_116526277 20.26 ENST00000393468.1
ENST00000393467.1
caveolin 1
chr8_-_54022441 19.93 ENST00000396401.7
ENST00000521604.7
ENST00000640382.1
ENST00000640041.1
transcription elongation factor A1
chr2_-_10812706 18.83 ENST00000272227.8
protein disulfide isomerase family A member 6
chr2_+_74206384 18.06 ENST00000678623.1
ENST00000678731.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr14_+_20455968 17.67 ENST00000438886.1
apurinic/apyrimidinic endodeoxyribonuclease 1
chr15_-_60398733 17.60 ENST00000559818.6
annexin A2
chr5_+_160421847 17.55 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr6_-_8102481 17.51 ENST00000502429.5
ENST00000429723.6
ENST00000379715.10
ENST00000507463.1
eukaryotic translation elongation factor 1 epsilon 1
chr15_+_41332862 16.85 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr2_+_27628996 16.14 ENST00000616939.4
ENST00000264718.7
ENST00000610189.2
GPN-loop GTPase 1
chr11_+_102112445 15.95 ENST00000524575.5
Yes1 associated transcriptional regulator
chr3_+_172040554 15.44 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr6_+_26538338 15.41 ENST00000377575.3
high mobility group nucleosomal binding domain 4
chr14_+_61697622 15.07 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr22_+_41621977 14.92 ENST00000405506.2
X-ray repair cross complementing 6
chr3_-_53255990 14.72 ENST00000423525.6
transketolase
chr1_+_44739825 14.49 ENST00000372224.9
kinesin family member 2C
chr2_-_10812794 14.38 ENST00000540494.5
protein disulfide isomerase family A member 6
chrX_+_49171889 14.36 ENST00000376327.6
proteolipid protein 2
chr12_+_65824475 14.01 ENST00000403681.7
high mobility group AT-hook 2
chr2_+_73828916 14.00 ENST00000339566.7
ENST00000683349.1
ENST00000682157.1
ENST00000682851.1
ENST00000394070.7
ENST00000409707.6
ENST00000684585.1
ENST00000683434.1
ENST00000682352.1
ENST00000424659.6
ENST00000536064.2
ENST00000684355.1
ENST00000682998.1
ENST00000682799.1
ENST00000394073.6
ENST00000682848.1
ENST00000683877.1
ENST00000682351.1
ENST00000683818.1
ENST00000683391.1
ENST00000682558.1
STAM binding protein
chr17_-_42016680 13.89 ENST00000674497.1
DnaJ heat shock protein family (Hsp40) member C7
chr12_-_13000166 13.77 ENST00000647702.1
heme binding protein 1
chr11_-_11353241 13.67 ENST00000528848.3
casein kinase 2 alpha 3
chr12_+_75480745 13.43 ENST00000266659.8
GLI pathogenesis related 1
chr1_-_149927756 13.41 ENST00000271628.9
splicing factor 3b subunit 4
chr2_+_200306048 13.39 ENST00000409988.7
ENST00000409385.5
spermatogenesis associated serine rich 2 like
chr19_-_42302576 13.33 ENST00000262890.8
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr3_-_146544636 13.20 ENST00000486631.5
phospholipid scramblase 1
chr17_-_58353069 13.17 ENST00000580947.1
SPT4 homolog, DSIF elongation factor subunit
chr17_-_48101379 12.75 ENST00000581003.5
ENST00000225603.9
chromobox 1
chr3_-_53256009 12.74 ENST00000296289.10
ENST00000462138.6
ENST00000423516.5
transketolase
chr12_-_50025394 12.34 ENST00000454520.6
ENST00000546595.5
ENST00000548824.5
ENST00000549777.5
ENST00000546723.5
ENST00000427314.6
ENST00000552157.5
ENST00000552310.5
ENST00000548644.5
ENST00000546786.5
ENST00000550149.5
ENST00000546764.5
ENST00000552004.2
ENST00000548320.5
ENST00000312377.10
ENST00000547905.5
ENST00000550651.5
ENST00000551145.5
ENST00000552921.5
Rac GTPase activating protein 1
chr8_+_103298433 12.26 ENST00000522566.5
frizzled class receptor 6
chr1_+_155613221 11.91 ENST00000462250.2
misato mitochondrial distribution and morphology regulator 1
chr13_+_52455972 11.69 ENST00000490903.5
ENST00000480747.1
cytoskeleton associated protein 2
chr6_+_30328889 11.64 ENST00000396547.5
ENST00000623385.3
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr11_+_119084873 11.45 ENST00000652429.1
ENST00000442944.7
ENST00000537841.5
ENST00000542729.5
ENST00000546302.6
ENST00000536813.6
ENST00000544387.5
ENST00000543090.5
hydroxymethylbilane synthase
chr14_+_20455185 11.38 ENST00000555414.5
ENST00000553681.5
apurinic/apyrimidinic endodeoxyribonuclease 1
chr2_+_200889327 11.36 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr4_+_112637120 11.30 ENST00000509061.5
ENST00000344442.10
ENST00000508577.5
ENST00000513553.5
La ribonucleoprotein 7, transcriptional regulator
chr3_-_146544578 11.21 ENST00000342435.9
ENST00000448787.6
phospholipid scramblase 1
chr18_+_3247778 11.15 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
myosin light chain 12A
chr11_+_60914139 11.04 ENST00000227525.8
transmembrane protein 109
chr10_-_70888546 11.03 ENST00000299299.4
pterin-4 alpha-carbinolamine dehydratase 1
chr15_+_48331403 11.02 ENST00000558813.5
ENST00000331200.8
ENST00000558472.5
deoxyuridine triphosphatase
chr17_-_7687427 11.01 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
tumor protein p53
chr5_+_34656288 11.00 ENST00000265109.8
retinoic acid induced 14
chr11_-_62671540 10.99 ENST00000532208.5
ENST00000377954.3
ENST00000431002.6
ENST00000354588.7
ENST00000415855.6
LBH domain containing 1
chr10_-_27154365 10.85 ENST00000396296.7
ENST00000376016.8
ENST00000491542.6
ENST00000613434.4
YME1 like 1 ATPase
chr1_-_110407633 10.81 ENST00000483260.5
ENST00000474861.6
ENST00000602318.6
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr8_-_65634138 10.80 ENST00000518908.5
ENST00000276569.8
ENST00000519352.1
armadillo repeat containing 1
chr3_-_146544538 10.72 ENST00000462666.5
phospholipid scramblase 1
chr15_-_41332487 10.68 ENST00000560640.1
ENST00000220514.8
Opa interacting protein 5
chr11_+_119085200 10.65 ENST00000650101.1
hydroxymethylbilane synthase
chr14_+_96502358 10.59 ENST00000216277.13
ENST00000557320.5
ENST00000557471.5
poly(A) polymerase alpha
chr19_-_291132 10.58 ENST00000327790.7
phospholipid phosphatase 2
chr7_-_7640009 10.36 ENST00000401447.1
replication protein A3
chr16_+_67570741 10.36 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CCCTC-binding factor
chr8_-_80030232 10.33 ENST00000518271.1
ENST00000276585.9
ENST00000521605.1
mitochondrial ribosomal protein S28
chr8_-_65634202 10.29 ENST00000458464.3
armadillo repeat containing 1
chr1_-_93879198 10.27 ENST00000436063.7
deoxynucleotidyltransferase terminal interacting protein 2
chr2_-_160407874 10.21 ENST00000409972.5
RNA binding motif single stranded interacting protein 1
chr15_-_84716063 10.09 ENST00000558217.5
ENST00000558196.1
ENST00000558134.5
SEC11 homolog A, signal peptidase complex subunit
chr1_+_181088692 10.08 ENST00000367577.7
immediate early response 5
chr2_-_135876382 9.94 ENST00000264156.3
minichromosome maintenance complex component 6
chr1_-_88992924 9.79 ENST00000370486.1
ENST00000399794.6
kynurenine aminotransferase 3
RBMX like 1
chr15_-_84716099 9.74 ENST00000560266.5
SEC11 homolog A, signal peptidase complex subunit
chr18_+_9103959 9.65 ENST00000400033.1
NADH:ubiquinone oxidoreductase core subunit V2
chr4_-_105708639 9.64 ENST00000416543.5
ENST00000515819.1
ENST00000420368.6
ENST00000503746.5
ENST00000433009.1
ENST00000340139.10
integrator complex subunit 12
chr10_-_27154226 9.62 ENST00000427324.5
ENST00000375972.7
ENST00000326799.7
YME1 like 1 ATPase
chr3_+_100709424 9.62 ENST00000675246.1
ENST00000675692.1
ENST00000675890.1
ENST00000675586.1
ENST00000674645.1
ENST00000675958.1
ENST00000479672.6
ENST00000675420.1
ENST00000674615.1
ENST00000676431.1
ENST00000674758.1
trafficking from ER to golgi regulator
chr4_-_103198331 9.57 ENST00000265148.9
ENST00000514974.1
centromere protein E
chr2_+_191276885 9.56 ENST00000392316.5
myosin IB
chr12_+_75480800 9.54 ENST00000456650.7
GLI pathogenesis related 1
chr12_+_10505890 9.49 ENST00000538173.1
eukaryotic translation initiation factor 2 subunit gamma B
chr11_+_59142811 9.36 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr15_-_84716153 9.28 ENST00000455959.7
SEC11 homolog A, signal peptidase complex subunit
chr6_+_63211446 9.26 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr15_-_84716129 9.17 ENST00000268220.12
SEC11 homolog A, signal peptidase complex subunit
chr2_-_55269207 9.03 ENST00000263629.9
ENST00000403721.5
mitochondrial translational initiation factor 2
chr1_-_88992616 8.96 ENST00000260508.9
ENST00000652648.1
kynurenine aminotransferase 3
RBMX like 1
chr12_-_13000208 8.91 ENST00000014930.9
ENST00000536942.1
heme binding protein 1
chr3_+_100709473 8.91 ENST00000240851.9
ENST00000675243.1
ENST00000676111.1
ENST00000476228.5
ENST00000463568.6
ENST00000676395.1
trafficking from ER to golgi regulator
chr19_+_19405655 8.84 ENST00000683918.1
GATA zinc finger domain containing 2A
chr11_+_65040895 8.83 ENST00000531072.1
ENST00000398846.6
SAC3 domain containing 1
chr6_-_79234713 8.83 ENST00000620514.1
high mobility group nucleosomal binding domain 3
chr6_-_79234619 8.81 ENST00000344726.9
ENST00000275036.11
high mobility group nucleosomal binding domain 3
chr4_-_103198371 8.78 ENST00000611174.4
ENST00000380026.8
centromere protein E
chr14_+_35292374 8.63 ENST00000261479.9
ENST00000553809.5
proteasome 20S subunit alpha 6
chr6_+_110874775 8.48 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr10_+_12196172 8.43 ENST00000281141.9
ENST00000378900.6
ENST00000442050.5
cell division cycle 123
chr1_+_158930778 8.42 ENST00000458222.5
pyrin and HIN domain family member 1
chr2_+_200306519 8.41 ENST00000360760.9
spermatogenesis associated serine rich 2 like
chr5_-_82278396 8.40 ENST00000510019.5
ribosomal protein S23
chr19_-_8005590 8.38 ENST00000407627.7
ENST00000593807.1
ELAV like RNA binding protein 1
chr8_-_73294425 8.30 ENST00000396465.5
ribosomal protein L7
chr6_+_159790448 8.20 ENST00000367034.5
mitochondrial ribosomal protein L18
chr1_+_193060034 8.17 ENST00000367446.7
ENST00000367443.5
ENST00000367444.7
ENST00000367445.7
Ro60, Y RNA binding protein
chr8_-_123042122 8.09 ENST00000405944.7
derlin 1
chr19_+_57363469 8.05 ENST00000282282.4
ENST00000543226.2
ENST00000596755.1
ENST00000597658.1
zinc finger protein 547
trafficking protein particle complex 2B
novel protein
chr6_-_113971120 7.95 ENST00000520895.5
ENST00000521163.5
ENST00000524334.1
ENST00000519065.6
ENST00000368632.6
histone deacetylase 2
chr1_-_6393750 7.83 ENST00000545482.5
ENST00000361521.9
acyl-CoA thioesterase 7
chr3_+_100709344 7.75 ENST00000418917.7
ENST00000675553.1
trafficking from ER to golgi regulator
chr9_-_14300231 7.73 ENST00000636735.1
nuclear factor I B
chr1_-_68497030 7.72 ENST00000456315.7
ENST00000525124.1
ENST00000370966.9
DEP domain containing 1
chr11_-_78139258 7.70 ENST00000530910.6
ENST00000681417.1
ENST00000681225.1
ENST00000681765.1
ENST00000525870.6
ENST00000530608.6
ENST00000532306.6
ENST00000376156.7
ENST00000681699.1
ENST00000681221.1
ENST00000679444.1
ENST00000680829.1
ENST00000680761.1
ENST00000680256.1
ENST00000525783.6
ENST00000529139.6
ENST00000680580.1
ENST00000526849.6
ENST00000680399.1
ENST00000527099.2
ENST00000681489.1
ENST00000299626.10
ENST00000679497.1
ENST00000680101.1
ENST00000532440.6
ENST00000530454.6
ENST00000525761.3
ENST00000681575.1
ENST00000679559.1
ENST00000680398.1
ENST00000615266.5
ENST00000680643.1
ALG8 alpha-1,3-glucosyltransferase
chr19_-_16660104 7.64 ENST00000593459.5
ENST00000627144.2
ENST00000358726.6
ENST00000487416.7
ENST00000597711.5
novel protein
small integral membrane protein 7
chr6_+_85449584 7.64 ENST00000369651.7
5'-nucleotidase ecto
chr12_+_64404338 7.50 ENST00000332707.10
exportin for tRNA
chr3_+_100709382 7.46 ENST00000620299.5
trafficking from ER to golgi regulator
chr1_-_88992732 7.42 ENST00000413769.1
ENST00000321792.5
ENST00000370491.7
RBMX like 1
kynurenine aminotransferase 3
chr16_-_50368779 7.39 ENST00000394689.2
bromodomain containing 7
chr14_+_35292308 7.39 ENST00000628955.1
ENST00000627895.2
ENST00000622405.4
proteasome 20S subunit alpha 6
chr6_-_53510445 7.38 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr1_+_226063466 7.35 ENST00000666609.1
ENST00000661429.1
H3.3 histone A
chr6_-_52284677 7.35 ENST00000596288.7
ENST00000616552.4
ENST00000229854.12
ENST00000419835.8
minichromosome maintenance complex component 3
chr18_+_59899988 7.26 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr16_-_11782552 7.18 ENST00000396516.6
zinc finger CCCH-type containing 7A
chr19_+_36214602 7.18 ENST00000456324.5
zinc finger protein 146
chr6_-_111567271 7.16 ENST00000464903.1
ENST00000368730.5
ENST00000368735.1
TRAF3 interacting protein 2
chr5_+_76819022 7.16 ENST00000296677.5
F2R like trypsin receptor 1
chr12_-_46372763 7.15 ENST00000256689.10
solute carrier family 38 member 2
chr6_-_42217845 7.14 ENST00000053468.4
mitochondrial ribosomal protein S10
chr22_-_37244237 7.12 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr10_+_13161543 7.05 ENST00000378714.8
ENST00000479669.5
ENST00000484800.6
minichromosome maintenance 10 replication initiation factor
chrX_+_51893533 7.04 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr11_-_95910748 7.02 ENST00000675933.1
myotubularin related protein 2
chr17_+_59707636 6.99 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr2_-_157874976 6.97 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
activin A receptor type 1
chr5_+_43120883 6.95 ENST00000515326.5
ENST00000682664.1
zinc finger protein 131
chr17_+_40287861 6.94 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr14_+_35292429 6.89 ENST00000555764.5
ENST00000556506.1
proteasome 20S subunit alpha 6
chr2_+_176269473 6.85 ENST00000452865.1
metaxin 2
chr2_+_218245426 6.79 ENST00000456575.1
actin related protein 2/3 complex subunit 2
chr12_+_22625075 6.77 ENST00000671733.1
ENST00000335148.8
ENST00000672951.1
ENST00000266517.9
ethanolamine kinase 1
chr5_+_65926556 6.64 ENST00000380943.6
ENST00000416865.6
ENST00000380935.5
ENST00000284037.10
erbb2 interacting protein
chr2_+_200889411 6.64 ENST00000409357.5
ENST00000409129.2
NGG1 interacting factor 3 like 1
chr9_+_125261788 6.57 ENST00000461379.5
ENST00000297933.11
ENST00000394084.5
ENST00000394105.6
ENST00000470056.5
ENST00000394083.6
ENST00000495955.5
ENST00000467750.5
GTPase activating protein and VPS9 domains 1
chr4_+_94489030 6.49 ENST00000510099.5
PDZ and LIM domain 5
chr3_-_15797930 6.41 ENST00000683139.1
ankyrin repeat domain 28
chr1_-_246193727 6.40 ENST00000391836.3
SET and MYND domain containing 3
chr17_-_75046951 6.32 ENST00000301587.9
ENST00000344546.8
ATP synthase peripheral stalk subunit d
chr1_+_154220179 6.30 ENST00000343815.10
ubiquitin associated protein 2 like
chr4_-_75672868 6.30 ENST00000678123.1
ENST00000678578.1
ENST00000677876.1
ENST00000676839.1
ENST00000678265.1
G3BP stress granule assembly factor 2
chr1_+_21440113 6.30 ENST00000454000.6
ENST00000318249.10
ENST00000342104.9
NBPF member 3
chr17_-_80147118 6.28 ENST00000649764.2
eukaryotic translation initiation factor 4A3
chr2_+_208266241 6.28 ENST00000264380.9
ENST00000392202.7
ENST00000407449.5
ENST00000308862.10
phosphoinositide kinase, FYVE-type zinc finger containing
chr10_+_110567666 6.27 ENST00000361804.5
structural maintenance of chromosomes 3
chr4_+_112637456 6.21 ENST00000505034.5
ENST00000324052.10
La ribonucleoprotein 7, transcriptional regulator
chr1_-_6393339 6.20 ENST00000608083.5
acyl-CoA thioesterase 7
chr8_-_73293616 6.10 ENST00000352983.7
ENST00000396467.5
ribosomal protein L7
chr19_+_36139953 6.08 ENST00000589146.5
ENST00000628018.2
ENST00000628306.2
calpain small subunit 1
chr10_-_70170466 6.06 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr18_-_49491586 6.05 ENST00000584895.5
ENST00000580210.5
ENST00000579408.5
RPL17-C18orf32 readthrough
ribosomal protein L17
chr1_-_154627576 6.01 ENST00000648311.1
adenosine deaminase RNA specific
chr1_-_77683356 6.01 ENST00000414381.5
ENST00000370798.5
zinc finger ZZ-type containing 3
chr5_+_129094691 5.98 ENST00000173527.6
ENST00000514194.5
isochorismatase domain containing 1
chr5_+_154858594 5.96 ENST00000519430.5
ENST00000520671.5
ENST00000521583.5
ENST00000285896.11
ENST00000518028.5
ENST00000519404.5
ENST00000519394.5
ENST00000518775.5
CCR4-NOT transcription complex subunit 8
chr1_-_93180377 5.93 ENST00000370282.8
transmembrane p24 trafficking protein 5
chr3_+_124730428 5.86 ENST00000628619.1
ENST00000232607.7
uridine monophosphate synthetase
chr20_+_1118590 5.85 ENST00000246015.8
ENST00000335877.11
proteasome inhibitor subunit 1
chr16_-_67936808 5.85 ENST00000358514.9
proteasome 20S subunit beta 10
chr12_+_75481204 5.78 ENST00000550491.1
GLI pathogenesis related 1
chr6_+_52671080 5.74 ENST00000211314.5
transmembrane protein 14A
chr16_-_20806431 5.71 ENST00000357967.9
ENST00000300005.7
ENST00000569729.5
ERI1 exoribonuclease family member 2
chr3_+_25790076 5.69 ENST00000280701.8
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr19_+_5690255 5.64 ENST00000582463.5
ENST00000347512.8
ENST00000579446.1
ENST00000394580.2
ribosomal protein L36
chrX_-_100636799 5.63 ENST00000373020.9
tetraspanin 6
chr17_-_80147137 5.61 ENST00000576547.2
ENST00000647795.1
eukaryotic translation initiation factor 4A3
chr3_+_130850585 5.60 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr5_-_144170607 5.59 ENST00000448443.6
ENST00000513112.5
ENST00000519064.5
ENST00000274496.10
ENST00000522203.5
Yip1 domain family member 5
chr2_+_200306340 5.55 ENST00000451764.6
spermatogenesis associated serine rich 2 like
chr8_-_123042244 5.55 ENST00000259512.9
ENST00000419562.6
derlin 1
chr4_+_112637514 5.54 ENST00000651579.1
La ribonucleoprotein 7, transcriptional regulator
chr6_+_26457941 5.51 ENST00000493173.1
ENST00000312541.10
ENST00000429381.5
ENST00000469185.5
butyrophilin subfamily 2 member A1
chr12_+_56128217 5.46 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chrX_+_48476021 5.45 ENST00000396894.8
ENST00000019019.6
ENST00000348411.3
FtsJ RNA 2'-O-methyltransferase 1
chr1_-_244864526 5.38 ENST00000640218.2
heterogeneous nuclear ribonucleoprotein U
chr3_-_149086488 5.38 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
helicase like transcription factor
chr12_+_53461015 5.38 ENST00000553064.6
ENST00000547859.2
poly(rC) binding protein 2
chr11_+_65860394 5.34 ENST00000308110.9
MUS81 structure-specific endonuclease subunit
chr6_+_26457904 5.30 ENST00000541522.5
butyrophilin subfamily 2 member A1
chrX_-_15493234 5.30 ENST00000380420.10
pirin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.7 50.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
16.5 49.5 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
9.2 27.5 GO:0005999 xylulose biosynthetic process(GO:0005999)
7.4 22.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
6.9 20.7 GO:1903778 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
5.4 16.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
5.3 16.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
5.1 20.3 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
4.7 14.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
4.4 35.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
4.4 26.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
3.9 19.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
3.7 11.0 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
3.5 17.6 GO:0044111 development involved in symbiotic interaction(GO:0044111)
3.1 12.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
3.1 12.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
3.1 18.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
3.0 11.9 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
2.7 8.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
2.6 20.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
2.5 15.1 GO:0070101 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
2.5 7.4 GO:1904387 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
2.4 7.2 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
2.3 7.0 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
2.3 13.6 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
2.1 14.9 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
2.1 10.4 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
2.1 6.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
2.1 26.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.0 8.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
2.0 17.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.0 5.9 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.8 16.0 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
1.7 6.9 GO:1904116 traversing start control point of mitotic cell cycle(GO:0007089) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
1.7 5.1 GO:1903487 regulation of lactation(GO:1903487)
1.6 16.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.6 17.5 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
1.6 18.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.5 4.4 GO:0014016 neuroblast differentiation(GO:0014016)
1.5 4.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.4 7.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
1.4 11.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.4 12.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
1.4 38.3 GO:0006465 signal peptide processing(GO:0006465)
1.3 6.6 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
1.3 3.9 GO:0044565 dendritic cell proliferation(GO:0044565)
1.3 5.2 GO:0035407 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) histone H3-T11 phosphorylation(GO:0035407)
1.3 7.6 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
1.2 8.5 GO:0008215 spermine metabolic process(GO:0008215) spermidine biosynthetic process(GO:0008295)
1.2 3.5 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
1.1 3.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
1.1 3.3 GO:0009183 purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dGDP metabolic process(GO:0046066)
1.1 15.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.1 5.3 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
1.0 7.3 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
1.0 9.0 GO:0032790 ribosome disassembly(GO:0032790)
1.0 7.0 GO:0032328 alanine transport(GO:0032328)
1.0 35.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.9 5.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.9 2.8 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.9 21.9 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.9 9.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.8 3.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.8 9.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.8 9.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.8 13.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.8 2.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.8 4.7 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.8 4.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 4.9 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.7 2.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.7 7.7 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 3.4 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.7 13.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.7 3.3 GO:0030070 insulin processing(GO:0030070)
0.6 31.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.6 6.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.6 35.0 GO:0043486 histone exchange(GO:0043486)
0.6 25.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.6 1.8 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.6 3.0 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.6 33.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.6 2.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 0.6 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.6 4.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.6 18.1 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.6 5.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.6 9.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.6 10.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 5.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.6 3.9 GO:0045007 depurination(GO:0045007)
0.6 11.6 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.6 8.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.5 12.5 GO:0018126 protein hydroxylation(GO:0018126)
0.5 3.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.5 1.5 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.5 21.2 GO:2000816 homologous chromosome segregation(GO:0045143) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.5 45.5 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.5 8.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.5 3.7 GO:0030091 protein repair(GO:0030091)
0.5 6.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.4 3.1 GO:0001302 replicative cell aging(GO:0001302)
0.4 4.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 9.6 GO:0016180 snRNA processing(GO:0016180)
0.4 3.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.4 5.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 3.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 43.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.4 2.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) glossopharyngeal nerve development(GO:0021563)
0.4 2.9 GO:0032808 lacrimal gland development(GO:0032808)
0.4 0.4 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.4 2.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 0.8 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 14.1 GO:0006270 DNA replication initiation(GO:0006270)
0.4 2.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4 7.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4 5.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 3.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 4.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 1.8 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 7.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.4 14.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.4 7.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 1.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.3 3.3 GO:0045116 protein neddylation(GO:0045116)
0.3 6.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.3 6.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.3 6.0 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.3 11.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 3.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 6.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 2.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 19.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 4.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 4.4 GO:0030916 otic vesicle formation(GO:0030916)
0.3 8.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 6.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 3.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 1.0 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.2 7.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 27.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.2 6.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.2 10.6 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.2 4.5 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.2 17.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 3.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 3.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 3.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.1 GO:0032202 telomere assembly(GO:0032202)
0.2 1.1 GO:0030242 pexophagy(GO:0030242)
0.2 3.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.5 GO:0070828 heterochromatin organization(GO:0070828)
0.2 3.3 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 2.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 1.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 6.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 3.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.2 15.5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 0.8 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.2 7.4 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 2.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 1.5 GO:0035865 cellular response to potassium ion(GO:0035865)
0.2 6.4 GO:0014904 myotube cell development(GO:0014904)
0.2 3.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 7.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.2 1.4 GO:0051601 exocyst localization(GO:0051601)
0.2 1.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.5 GO:0097272 ammonia homeostasis(GO:0097272)
0.2 4.0 GO:0030488 tRNA methylation(GO:0030488)
0.2 4.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 5.4 GO:0006301 postreplication repair(GO:0006301)
0.1 3.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 3.6 GO:0031639 plasminogen activation(GO:0031639)
0.1 9.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 9.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.9 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.1 6.2 GO:0018208 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.1 5.9 GO:0030224 monocyte differentiation(GO:0030224)
0.1 2.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 1.9 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.9 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.7 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.1 2.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 3.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.7 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 3.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.9 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 9.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 10.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 2.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.1 4.4 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 4.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 2.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 1.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.9 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.1 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.9 GO:0036258 multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258)
0.1 1.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 11.2 GO:0007623 circadian rhythm(GO:0007623)
0.0 6.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 1.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 1.6 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 5.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 3.9 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:1990785 initiation of primordial ovarian follicle growth(GO:0001544) response to water-immersion restraint stress(GO:1990785)
0.0 2.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 16.2 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 3.9 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.6 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 2.3 GO:0006260 DNA replication(GO:0006260)
0.0 2.0 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 27.8 GO:0031262 Ndc80 complex(GO:0031262)
5.6 50.1 GO:0036449 microtubule minus-end(GO:0036449) meiotic spindle(GO:0072687)
5.3 16.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
4.3 38.3 GO:0005787 signal peptidase complex(GO:0005787)
3.4 13.6 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
3.1 25.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
3.0 14.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
3.0 29.6 GO:0043203 axon hillock(GO:0043203)
2.9 17.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
2.7 10.8 GO:0071986 Ragulator complex(GO:0071986)
2.6 13.2 GO:0032044 DSIF complex(GO:0032044)
2.6 38.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.5 17.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
2.5 12.3 GO:0097149 centralspindlin complex(GO:0097149)
2.5 7.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
2.3 6.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.1 12.7 GO:0001940 male pronucleus(GO:0001940)
2.1 6.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
2.0 14.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.9 9.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
1.9 22.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.7 7.0 GO:0048179 activin receptor complex(GO:0048179)
1.7 18.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.6 47.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.6 20.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.4 26.0 GO:0000812 Swr1 complex(GO:0000812)
1.3 17.0 GO:0042555 MCM complex(GO:0042555)
1.0 19.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.0 15.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.9 27.9 GO:0031143 pseudopodium(GO:0031143)
0.9 4.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.9 9.6 GO:0032039 integrator complex(GO:0032039)
0.9 6.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.8 5.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.8 2.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.8 17.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.8 8.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.8 7.1 GO:0031298 replication fork protection complex(GO:0031298)
0.7 2.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.7 2.9 GO:0070435 Shc-EGFR complex(GO:0070435)
0.7 2.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.6 3.2 GO:0001651 dense fibrillar component(GO:0001651)
0.6 1.9 GO:0071817 MMXD complex(GO:0071817)
0.6 17.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.6 10.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.6 1.8 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.6 10.7 GO:0010369 chromocenter(GO:0010369)
0.6 28.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.6 3.3 GO:0005638 lamin filament(GO:0005638)
0.5 4.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.5 14.5 GO:0035371 microtubule plus-end(GO:0035371)
0.5 16.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5 2.4 GO:1902560 GMP reductase complex(GO:1902560)
0.5 56.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.5 5.9 GO:0005839 proteasome core complex(GO:0005839)
0.4 1.3 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.4 3.0 GO:0031415 NatA complex(GO:0031415)
0.4 4.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.4 2.9 GO:0005610 laminin-5 complex(GO:0005610)
0.4 6.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 12.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 1.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.4 6.6 GO:0030056 hemidesmosome(GO:0030056)
0.4 26.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 27.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 4.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 8.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 1.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 0.9 GO:0033565 ESCRT-0 complex(GO:0033565)
0.3 0.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 4.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 16.8 GO:0005876 spindle microtubule(GO:0005876)
0.3 6.9 GO:0051233 spindle midzone(GO:0051233)
0.3 4.1 GO:0008091 spectrin(GO:0008091)
0.3 5.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 2.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 1.0 GO:0033263 CORVET complex(GO:0033263)
0.3 14.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 12.1 GO:1904115 axon cytoplasm(GO:1904115)
0.3 10.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 4.4 GO:0005916 fascia adherens(GO:0005916)
0.2 1.9 GO:0031931 TORC1 complex(GO:0031931)
0.2 7.0 GO:0000421 pre-autophagosomal structure(GO:0000407) autophagosome membrane(GO:0000421)
0.2 3.3 GO:0005642 annulate lamellae(GO:0005642)
0.2 4.1 GO:0030904 retromer complex(GO:0030904)
0.2 3.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 2.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 8.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 18.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 4.1 GO:0046930 pore complex(GO:0046930)
0.2 7.6 GO:0090544 BAF-type complex(GO:0090544)
0.2 16.5 GO:0016459 myosin complex(GO:0016459)
0.2 10.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 4.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 2.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.2 GO:0070552 BRISC complex(GO:0070552)
0.1 3.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 2.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 15.7 GO:0001650 fibrillar center(GO:0001650)
0.1 1.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 20.7 GO:0043209 myelin sheath(GO:0043209)
0.1 1.5 GO:0000786 nucleosome(GO:0000786)
0.1 2.2 GO:0031527 filopodium membrane(GO:0031527)
0.1 79.1 GO:0005730 nucleolus(GO:0005730)
0.1 3.5 GO:0002102 podosome(GO:0002102)
0.1 7.1 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.4 GO:0000145 exocyst(GO:0000145)
0.1 5.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 40.2 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.1 1.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 25.9 GO:0000785 chromatin(GO:0000785)
0.1 8.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 1.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 6.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.1 GO:0031201 SNARE complex(GO:0031201)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 11.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 8.2 GO:0005874 microtubule(GO:0005874)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 49.5 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
8.7 26.2 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
7.4 22.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
6.9 27.5 GO:0004802 transketolase activity(GO:0004802)
6.0 29.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
5.1 20.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
4.6 18.4 GO:0043515 kinetochore binding(GO:0043515)
4.5 18.1 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.7 11.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
3.5 17.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
3.5 10.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
3.2 28.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.8 11.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
2.7 13.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
2.6 7.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
2.5 7.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
2.2 35.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
2.2 17.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
2.0 28.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.9 38.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
1.9 5.7 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
1.8 14.5 GO:0019237 centromeric DNA binding(GO:0019237)
1.7 11.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.6 9.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
1.6 14.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.5 10.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.5 4.4 GO:0033265 choline binding(GO:0033265)
1.4 12.7 GO:1990226 histone methyltransferase binding(GO:1990226)
1.4 63.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.3 5.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.2 7.2 GO:0015057 thrombin receptor activity(GO:0015057)
1.2 7.0 GO:0016361 activin receptor activity, type I(GO:0016361)
1.1 4.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.1 3.2 GO:0034512 box C/D snoRNA binding(GO:0034512)
1.0 6.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
1.0 6.3 GO:0036033 mediator complex binding(GO:0036033)
1.0 28.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 8.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.9 4.4 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.9 4.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.9 3.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.8 2.5 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.8 4.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.8 33.6 GO:0019956 chemokine binding(GO:0019956)
0.8 5.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.8 13.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.8 6.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.7 3.7 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.7 5.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.6 32.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.6 3.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.6 4.9 GO:0015288 porin activity(GO:0015288)
0.6 19.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.6 8.2 GO:0008097 5S rRNA binding(GO:0008097)
0.6 9.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 16.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.5 30.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.5 1.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.5 1.5 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.5 22.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.5 11.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 2.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.5 2.4 GO:0047115 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.5 3.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.5 8.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 4.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 3.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 15.5 GO:0001671 ATPase activator activity(GO:0001671)
0.4 7.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 4.1 GO:0042731 PH domain binding(GO:0042731)
0.4 2.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 14.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 6.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 9.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 6.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 6.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.4 6.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 6.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 1.0 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 3.4 GO:0031013 troponin I binding(GO:0031013)
0.3 7.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 18.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 9.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 2.8 GO:0008312 7S RNA binding(GO:0008312)
0.3 8.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 10.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 5.9 GO:0070628 proteasome binding(GO:0070628)
0.3 8.7 GO:0070064 proline-rich region binding(GO:0070064)
0.3 4.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 5.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 7.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 2.2 GO:0089720 caspase binding(GO:0089720)
0.2 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.2 4.4 GO:0051400 BH domain binding(GO:0051400)
0.2 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 2.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 6.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 9.1 GO:0004386 helicase activity(GO:0004386)
0.2 2.4 GO:0050700 CARD domain binding(GO:0050700)
0.2 3.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 0.6 GO:0032090 Pyrin domain binding(GO:0032090)
0.2 5.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 4.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 3.9 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.2 10.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 2.3 GO:0008432 JUN kinase binding(GO:0008432)
0.2 8.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 3.0 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 33.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 5.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 3.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 41.9 GO:0005516 calmodulin binding(GO:0005516)
0.2 1.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 23.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 17.1 GO:0032947 protein complex scaffold(GO:0032947)
0.1 3.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 5.7 GO:0004527 exonuclease activity(GO:0004527)
0.1 15.8 GO:0020037 heme binding(GO:0020037)
0.1 2.8 GO:0031489 myosin V binding(GO:0031489)
0.1 1.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 3.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 10.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.9 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein light chain binding(GO:0045503)
0.1 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.1 2.4 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.1 5.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 6.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 5.8 GO:0005525 GTP binding(GO:0005525)
0.1 11.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 19.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 3.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.1 1.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 15.3 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 11.4 GO:0008017 microtubule binding(GO:0008017)
0.0 2.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 4.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 27.6 GO:0003723 RNA binding(GO:0003723)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 43.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.0 25.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6 5.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 45.4 PID PLK1 PATHWAY PLK1 signaling events
0.6 27.2 PID ALK1 PATHWAY ALK1 signaling events
0.6 14.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.6 30.2 PID AURORA B PATHWAY Aurora B signaling
0.4 12.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 13.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 13.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 3.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 7.2 ST GA12 PATHWAY G alpha 12 Pathway
0.2 16.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 17.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 8.7 PID ATR PATHWAY ATR signaling pathway
0.2 5.4 PID ATM PATHWAY ATM pathway
0.2 10.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 2.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.5 PID IL23 PATHWAY IL23-mediated signaling events
0.1 10.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 9.2 PID BCR 5PATHWAY BCR signaling pathway
0.1 3.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 7.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 2.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 7.5 PID E2F PATHWAY E2F transcription factor network
0.1 5.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 7.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 4.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 2.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 53.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
2.2 42.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.9 17.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.2 17.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.0 28.5 REACTOME KINESINS Genes involved in Kinesins
0.9 14.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.9 33.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.9 26.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.9 24.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.8 18.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.8 14.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.8 20.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.7 13.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 24.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.6 9.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.6 20.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.6 25.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 44.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.6 44.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6 17.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.6 26.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.5 4.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.5 13.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.5 10.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.5 7.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 15.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 10.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 9.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 31.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 11.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 7.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 7.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 24.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 8.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 10.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 5.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 11.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 33.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 4.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 3.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 1.8 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2 4.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 14.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 6.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 4.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 11.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 5.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 8.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 17.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 1.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 14.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 9.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 5.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 6.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation