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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ID4_TCF4_SNAI2
Z-value: 8.59
Motif logo
Transcription factors associated with ID4_TCF4_SNAI2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ID4
|
ENSG00000172201.12 | ID4 |
|
TCF4
|
ENSG00000196628.20 | TCF4 |
|
SNAI2
|
ENSG00000019549.13 | SNAI2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SNAI2 | hg38_v1_chr8_-_48921419_48921437 | -0.56 | 2.1e-19 | Click! |
| TCF4 | hg38_v1_chr18_-_55422306_55422361 | 0.41 | 4.7e-10 | Click! |
| ID4 | hg38_v1_chr6_+_19837362_19837381 | 0.29 | 1.7e-05 | Click! |
Activity profile of ID4_TCF4_SNAI2 motif
Sorted Z-values of ID4_TCF4_SNAI2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ID4_TCF4_SNAI2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 40.7 | 122.1 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 24.5 | 73.4 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 19.0 | 19.0 | GO:0070861 | regulation of protein exit from endoplasmic reticulum(GO:0070861) |
| 18.5 | 92.3 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 17.1 | 51.3 | GO:0036292 | DNA rewinding(GO:0036292) |
| 16.3 | 49.0 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 16.0 | 48.0 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 15.6 | 46.9 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 15.0 | 75.0 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 14.8 | 73.8 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 14.3 | 57.2 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 13.9 | 41.7 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 13.8 | 41.4 | GO:2001151 | regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153) |
| 13.8 | 55.1 | GO:2000314 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 13.5 | 53.9 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 13.4 | 40.1 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 13.0 | 39.0 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 12.7 | 50.9 | GO:1904823 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 12.4 | 74.2 | GO:0070829 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 12.3 | 49.1 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 12.2 | 48.6 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 12.1 | 121.1 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 12.1 | 12.1 | GO:1902308 | regulation of peptidyl-serine dephosphorylation(GO:1902308) positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 12.0 | 204.0 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 11.9 | 83.0 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 11.7 | 35.2 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 11.6 | 34.9 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 11.5 | 57.3 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 11.4 | 68.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 11.1 | 133.6 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 10.8 | 43.0 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 10.7 | 74.8 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 10.5 | 52.5 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
| 10.5 | 94.5 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 10.3 | 30.9 | GO:1902809 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 10.2 | 204.1 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 10.0 | 60.1 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 10.0 | 40.0 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 9.9 | 29.8 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 9.7 | 29.1 | GO:2001303 | lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303) |
| 9.5 | 28.4 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 9.4 | 28.3 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 9.4 | 28.2 | GO:0036048 | protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699) |
| 9.3 | 9.3 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 9.2 | 36.9 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 9.2 | 36.8 | GO:1903611 | regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634) |
| 9.2 | 27.6 | GO:2000538 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 9.2 | 9.2 | GO:0036146 | cellular response to mycotoxin(GO:0036146) |
| 9.1 | 54.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 9.0 | 54.1 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 9.0 | 18.0 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 9.0 | 26.9 | GO:0001757 | somite specification(GO:0001757) |
| 8.8 | 70.5 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 8.7 | 8.7 | GO:0014901 | regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) |
| 8.7 | 43.6 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 8.3 | 24.8 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 8.2 | 32.7 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 8.1 | 97.7 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 7.9 | 31.8 | GO:0002159 | desmosome assembly(GO:0002159) |
| 7.9 | 23.7 | GO:0071206 | establishment of protein localization to juxtaparanode region of axon(GO:0071206) |
| 7.8 | 23.3 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 7.7 | 38.3 | GO:0097114 | NMDA glutamate receptor clustering(GO:0097114) |
| 7.7 | 7.7 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 7.6 | 22.7 | GO:0035691 | macrophage migration inhibitory factor signaling pathway(GO:0035691) |
| 7.6 | 37.8 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 7.5 | 29.8 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 7.4 | 51.8 | GO:0015705 | iodide transport(GO:0015705) |
| 7.3 | 36.7 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 7.3 | 29.3 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 7.3 | 14.6 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 7.3 | 14.5 | GO:0046689 | response to mercury ion(GO:0046689) |
| 7.3 | 7.3 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) |
| 7.2 | 57.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 7.1 | 28.4 | GO:0072660 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 7.0 | 28.0 | GO:0021775 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 7.0 | 20.9 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 7.0 | 69.6 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 7.0 | 62.7 | GO:0046959 | habituation(GO:0046959) |
| 7.0 | 20.9 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) |
| 6.9 | 13.8 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
| 6.8 | 47.7 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 6.7 | 106.6 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 6.5 | 39.1 | GO:0038016 | insulin receptor internalization(GO:0038016) |
| 6.4 | 19.3 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 6.3 | 6.3 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of muscle adaptation(GO:0014744) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 6.3 | 18.8 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 6.2 | 6.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 6.2 | 12.3 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
| 6.2 | 18.5 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 6.1 | 18.4 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777) |
| 6.1 | 24.4 | GO:0071110 | protein biotinylation(GO:0009305) histone biotinylation(GO:0071110) |
| 6.1 | 18.3 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 6.1 | 6.1 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 6.0 | 24.1 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 6.0 | 18.1 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 6.0 | 6.0 | GO:0005985 | sucrose metabolic process(GO:0005985) |
| 6.0 | 17.9 | GO:0019075 | virus maturation(GO:0019075) |
| 5.9 | 17.6 | GO:0051946 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 5.8 | 29.0 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 5.8 | 28.9 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 5.8 | 17.3 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 5.8 | 17.3 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 5.8 | 23.0 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 5.7 | 11.5 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
| 5.7 | 17.2 | GO:0071810 | circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 5.7 | 5.7 | GO:0001796 | type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) |
| 5.7 | 39.7 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 5.6 | 33.8 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 5.6 | 61.9 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 5.6 | 28.0 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 5.6 | 11.2 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 5.6 | 11.1 | GO:1903413 | cellular response to bile acid(GO:1903413) |
| 5.6 | 44.5 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 5.6 | 5.6 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 5.5 | 22.1 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 5.5 | 94.0 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 5.5 | 60.0 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 5.4 | 70.5 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 5.4 | 16.2 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 5.4 | 21.6 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 5.4 | 10.7 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 5.3 | 37.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 5.3 | 26.3 | GO:1902612 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 5.2 | 68.2 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 5.2 | 20.9 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 5.2 | 67.8 | GO:0042748 | circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188) |
| 5.1 | 20.6 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) |
| 5.1 | 10.3 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
| 5.1 | 30.6 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 5.1 | 5.1 | GO:0034146 | toll-like receptor 5 signaling pathway(GO:0034146) |
| 5.1 | 10.1 | GO:1990641 | response to iron ion starvation(GO:1990641) |
| 5.0 | 20.0 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 5.0 | 10.0 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 4.9 | 29.6 | GO:0009732 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 4.9 | 24.5 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 4.8 | 19.1 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 4.8 | 23.9 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 4.8 | 28.7 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 4.8 | 47.7 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 4.7 | 23.7 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 4.7 | 23.7 | GO:1905065 | positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 4.7 | 18.9 | GO:1901594 | detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594) |
| 4.7 | 183.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 4.7 | 9.4 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 4.7 | 18.7 | GO:0060327 | cytoplasmic actin-based contraction involved in cell motility(GO:0060327) |
| 4.6 | 4.6 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 4.6 | 18.3 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 4.6 | 27.4 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 4.6 | 4.6 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 4.5 | 31.5 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
| 4.5 | 13.5 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654) |
| 4.5 | 22.5 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 4.5 | 31.2 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 4.4 | 22.1 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 4.4 | 101.2 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 4.4 | 8.7 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 4.4 | 8.7 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 4.3 | 60.8 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 4.3 | 13.0 | GO:1904582 | regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582) |
| 4.3 | 12.9 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 4.3 | 42.8 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 4.3 | 8.5 | GO:0060492 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) |
| 4.2 | 17.0 | GO:1904640 | response to methionine(GO:1904640) |
| 4.2 | 12.7 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
| 4.2 | 16.9 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 4.2 | 8.4 | GO:0002876 | positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876) |
| 4.2 | 21.1 | GO:0016240 | autophagosome docking(GO:0016240) |
| 4.2 | 12.6 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 4.2 | 21.0 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 4.2 | 8.4 | GO:0036484 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 4.2 | 8.4 | GO:0060032 | notochord regression(GO:0060032) |
| 4.2 | 16.6 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 4.1 | 4.1 | GO:0061526 | acetylcholine secretion(GO:0061526) |
| 4.1 | 12.4 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) |
| 4.1 | 24.8 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 4.1 | 12.4 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 4.1 | 41.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 4.1 | 8.2 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 4.1 | 8.2 | GO:0071315 | cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317) |
| 4.1 | 4.1 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 4.1 | 16.4 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 4.1 | 8.2 | GO:0007538 | primary sex determination(GO:0007538) |
| 4.1 | 12.2 | GO:2000851 | positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851) |
| 4.1 | 61.0 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 4.1 | 12.2 | GO:0038156 | interleukin-3-mediated signaling pathway(GO:0038156) |
| 4.0 | 16.2 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
| 4.0 | 20.1 | GO:0014850 | response to muscle activity(GO:0014850) |
| 4.0 | 20.1 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 4.0 | 12.0 | GO:0001983 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
| 4.0 | 12.0 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 4.0 | 27.9 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 4.0 | 15.9 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 4.0 | 43.6 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 4.0 | 31.7 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 4.0 | 15.8 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 4.0 | 4.0 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 3.9 | 27.6 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 3.9 | 63.0 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 3.9 | 27.6 | GO:2000768 | positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 3.9 | 35.4 | GO:1900004 | negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572) |
| 3.9 | 3.9 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 3.9 | 15.7 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 3.9 | 15.6 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 3.9 | 19.5 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 3.9 | 50.5 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 3.9 | 19.4 | GO:0007468 | regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872) |
| 3.9 | 15.5 | GO:0002399 | MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399) |
| 3.9 | 11.6 | GO:0071529 | cementum mineralization(GO:0071529) |
| 3.9 | 3.9 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
| 3.8 | 15.3 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 3.8 | 7.7 | GO:0052314 | isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314) |
| 3.8 | 7.6 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 3.8 | 22.8 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 3.8 | 11.4 | GO:0007525 | somatic muscle development(GO:0007525) |
| 3.8 | 26.4 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 3.8 | 11.3 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
| 3.7 | 18.7 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 3.7 | 22.5 | GO:0060313 | negative regulation of blood vessel remodeling(GO:0060313) |
| 3.7 | 11.2 | GO:0010266 | response to vitamin B1(GO:0010266) |
| 3.7 | 3.7 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 3.7 | 7.5 | GO:0071288 | cellular response to mercury ion(GO:0071288) |
| 3.7 | 3.7 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 3.7 | 14.9 | GO:0072011 | glomerular endothelium development(GO:0072011) |
| 3.7 | 14.9 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 3.7 | 29.7 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 3.7 | 48.0 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 3.7 | 3.7 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
| 3.7 | 47.7 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 3.7 | 14.6 | GO:0002727 | natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) |
| 3.6 | 58.2 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 3.6 | 47.2 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 3.6 | 54.3 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 3.6 | 21.7 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 3.6 | 54.1 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 3.6 | 14.3 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 3.6 | 14.3 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 3.6 | 53.7 | GO:0045187 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 3.6 | 21.4 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 3.6 | 7.1 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 3.6 | 3.6 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) |
| 3.5 | 7.1 | GO:0043217 | myelin maintenance(GO:0043217) |
| 3.5 | 10.6 | GO:0061218 | negative regulation of mesonephros development(GO:0061218) |
| 3.5 | 14.1 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 3.5 | 31.5 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 3.5 | 10.4 | GO:1902263 | apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 3.5 | 3.5 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 3.5 | 10.4 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 3.5 | 76.3 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 3.5 | 13.8 | GO:1990834 | response to odorant(GO:1990834) |
| 3.4 | 17.2 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 3.4 | 34.4 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 3.4 | 106.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 3.4 | 17.1 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 3.4 | 44.3 | GO:0086036 | regulation of cardiac muscle cell membrane potential(GO:0086036) |
| 3.4 | 13.6 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 3.4 | 10.2 | GO:0044771 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 3.3 | 10.0 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 3.3 | 26.7 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 3.3 | 16.5 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
| 3.3 | 26.4 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 3.3 | 19.8 | GO:0045976 | negative regulation of mitotic cell cycle, embryonic(GO:0045976) |
| 3.3 | 3.3 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 3.3 | 6.5 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 3.3 | 19.6 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 3.2 | 51.9 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 3.2 | 16.2 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 3.2 | 3.2 | GO:0009794 | regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448) |
| 3.2 | 6.4 | GO:0048808 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
| 3.2 | 22.5 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 3.2 | 16.1 | GO:1990164 | histone H2A phosphorylation(GO:1990164) |
| 3.2 | 57.7 | GO:0015671 | oxygen transport(GO:0015671) |
| 3.2 | 3.2 | GO:0021637 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 3.2 | 25.6 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 3.2 | 12.8 | GO:0019086 | late viral transcription(GO:0019086) |
| 3.2 | 19.2 | GO:0048241 | epinephrine transport(GO:0048241) |
| 3.2 | 3.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 3.2 | 6.4 | GO:0010046 | response to mycotoxin(GO:0010046) |
| 3.2 | 9.5 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 3.2 | 28.4 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 3.2 | 6.3 | GO:0090182 | regulation of secretion of lysosomal enzymes(GO:0090182) |
| 3.1 | 18.9 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 3.1 | 6.3 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 3.1 | 9.4 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 3.1 | 18.8 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 3.1 | 6.3 | GO:0000436 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) |
| 3.1 | 9.4 | GO:0061591 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 3.1 | 15.6 | GO:0010816 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 3.1 | 12.5 | GO:0071287 | cellular response to manganese ion(GO:0071287) |
| 3.1 | 15.6 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 3.1 | 15.6 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 3.1 | 12.4 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 3.1 | 12.4 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 3.1 | 21.6 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 3.1 | 37.0 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 3.1 | 24.6 | GO:0009155 | purine deoxyribonucleotide catabolic process(GO:0009155) |
| 3.1 | 30.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 3.1 | 9.2 | GO:1904692 | positive regulation of type B pancreatic cell proliferation(GO:1904692) |
| 3.1 | 45.8 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 3.1 | 24.4 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 3.1 | 15.3 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 3.1 | 12.2 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 3.0 | 6.1 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 3.0 | 57.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 3.0 | 9.0 | GO:0009386 | translational attenuation(GO:0009386) |
| 3.0 | 18.0 | GO:1901159 | glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159) |
| 3.0 | 3.0 | GO:1901858 | regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA replication(GO:0090298) regulation of mitochondrial DNA metabolic process(GO:1901858) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 3.0 | 8.9 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 3.0 | 11.8 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 3.0 | 8.9 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 2.9 | 2.9 | GO:0030320 | cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) |
| 2.9 | 29.1 | GO:1903358 | regulation of Golgi organization(GO:1903358) |
| 2.9 | 17.5 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 2.9 | 8.6 | GO:1900114 | positive regulation of histone H3-K9 trimethylation(GO:1900114) |
| 2.9 | 5.7 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
| 2.9 | 136.9 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 2.8 | 8.5 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 2.8 | 17.1 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 2.8 | 65.3 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 2.8 | 19.8 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 2.8 | 189.6 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 2.8 | 22.6 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 2.8 | 22.6 | GO:0021794 | thalamus development(GO:0021794) |
| 2.8 | 5.7 | GO:0002093 | auditory receptor cell morphogenesis(GO:0002093) |
| 2.8 | 14.1 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
| 2.8 | 8.4 | GO:0021558 | trochlear nerve development(GO:0021558) |
| 2.8 | 2.8 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 2.8 | 13.9 | GO:0038170 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 2.8 | 22.3 | GO:0061709 | reticulophagy(GO:0061709) |
| 2.8 | 13.9 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 2.8 | 5.5 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 2.8 | 2.8 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 2.8 | 11.1 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 2.8 | 11.0 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 2.8 | 24.9 | GO:0010226 | response to lithium ion(GO:0010226) |
| 2.8 | 5.5 | GO:2000412 | positive regulation of thymocyte migration(GO:2000412) |
| 2.7 | 5.5 | GO:1900619 | acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619) |
| 2.7 | 11.0 | GO:1903173 | phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173) |
| 2.7 | 10.9 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 2.7 | 16.4 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 2.7 | 8.2 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 2.7 | 5.4 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 2.7 | 18.9 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 2.7 | 10.8 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 2.7 | 8.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 2.7 | 16.1 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 2.7 | 32.1 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 2.7 | 10.6 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
| 2.6 | 15.9 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 2.6 | 7.9 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 2.6 | 13.1 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 2.6 | 52.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 2.6 | 7.8 | GO:0072530 | purine-containing compound transmembrane transport(GO:0072530) |
| 2.6 | 15.6 | GO:0045759 | negative regulation of action potential(GO:0045759) |
| 2.6 | 20.8 | GO:0003197 | endocardial cushion development(GO:0003197) |
| 2.6 | 7.7 | GO:1904397 | negative regulation of neuromuscular junction development(GO:1904397) |
| 2.6 | 2.6 | GO:0032252 | secretory granule localization(GO:0032252) |
| 2.6 | 10.2 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 2.6 | 5.1 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 2.6 | 53.6 | GO:0021854 | hypothalamus development(GO:0021854) |
| 2.5 | 50.9 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 2.5 | 17.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 2.5 | 7.6 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 2.5 | 2.5 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 2.5 | 10.1 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 2.5 | 20.1 | GO:0097186 | amelogenesis(GO:0097186) |
| 2.5 | 45.2 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 2.5 | 7.5 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 2.5 | 42.5 | GO:0046838 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 2.5 | 7.5 | GO:1902414 | protein localization to cell junction(GO:1902414) |
| 2.5 | 67.4 | GO:0071420 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
| 2.5 | 7.5 | GO:0002384 | hepatic immune response(GO:0002384) |
| 2.5 | 7.5 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 2.5 | 29.8 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 2.5 | 19.8 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 2.5 | 9.9 | GO:0035900 | response to isolation stress(GO:0035900) |
| 2.5 | 7.4 | GO:0006683 | galactosylceramide catabolic process(GO:0006683) |
| 2.5 | 49.2 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 2.5 | 19.6 | GO:0042426 | choline catabolic process(GO:0042426) |
| 2.4 | 7.3 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 2.4 | 4.9 | GO:0072244 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 2.4 | 4.8 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 2.4 | 4.8 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
| 2.4 | 7.2 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 2.4 | 12.1 | GO:0055118 | negative regulation of cardiac muscle contraction(GO:0055118) |
| 2.4 | 7.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 2.4 | 9.6 | GO:2000845 | androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
| 2.4 | 19.2 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 2.4 | 7.2 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 2.4 | 7.2 | GO:0003147 | neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231) |
| 2.4 | 23.9 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 2.4 | 23.9 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
| 2.4 | 4.8 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
| 2.4 | 7.2 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 2.4 | 4.8 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 2.4 | 68.4 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 2.4 | 4.7 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 2.3 | 32.9 | GO:1904152 | regulation of retrograde protein transport, ER to cytosol(GO:1904152) |
| 2.3 | 4.7 | GO:1905053 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 2.3 | 9.4 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 2.3 | 9.4 | GO:0042488 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 2.3 | 30.2 | GO:0060394 | negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 2.3 | 16.2 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 2.3 | 6.9 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 2.3 | 11.4 | GO:0019732 | antifungal humoral response(GO:0019732) |
| 2.3 | 111.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 2.3 | 6.8 | GO:1903892 | regulation of ATF6-mediated unfolded protein response(GO:1903891) negative regulation of ATF6-mediated unfolded protein response(GO:1903892) |
| 2.2 | 22.4 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 2.2 | 6.7 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 2.2 | 26.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 2.2 | 17.8 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 2.2 | 6.6 | GO:0038001 | paracrine signaling(GO:0038001) |
| 2.2 | 13.3 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 2.2 | 53.1 | GO:0051197 | positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 2.2 | 6.6 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 2.2 | 4.4 | GO:0035973 | aggrephagy(GO:0035973) |
| 2.2 | 19.9 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 2.2 | 6.6 | GO:0019557 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 2.2 | 37.2 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 2.2 | 21.8 | GO:0036065 | fucosylation(GO:0036065) |
| 2.2 | 17.4 | GO:0015747 | urate transport(GO:0015747) |
| 2.2 | 6.5 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 2.2 | 13.0 | GO:2001293 | malonyl-CoA metabolic process(GO:2001293) |
| 2.2 | 6.5 | GO:0048687 | modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 2.1 | 77.4 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 2.1 | 42.9 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 2.1 | 4.2 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 2.1 | 8.4 | GO:0072366 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 2.1 | 4.2 | GO:0035696 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 2.1 | 18.9 | GO:0070633 | transepithelial transport(GO:0070633) |
| 2.1 | 14.7 | GO:0044126 | regulation of growth of symbiont in host(GO:0044126) |
| 2.1 | 39.9 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 2.1 | 10.4 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 2.1 | 20.8 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 2.1 | 6.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 2.1 | 12.4 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 2.1 | 8.3 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 2.1 | 6.2 | GO:0010958 | response to herbicide(GO:0009635) regulation of amino acid import(GO:0010958) |
| 2.1 | 24.8 | GO:0001977 | renal system process involved in regulation of blood volume(GO:0001977) |
| 2.1 | 6.2 | GO:0060283 | negative regulation of oocyte development(GO:0060283) |
| 2.1 | 18.5 | GO:0015886 | heme transport(GO:0015886) |
| 2.1 | 61.7 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 2.1 | 6.2 | GO:0002725 | negative regulation of T cell cytokine production(GO:0002725) |
| 2.1 | 22.6 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 2.0 | 71.7 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 2.0 | 4.1 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 2.0 | 6.1 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 2.0 | 18.4 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 2.0 | 14.2 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 2.0 | 10.1 | GO:0033227 | dsRNA transport(GO:0033227) |
| 2.0 | 8.1 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 2.0 | 34.2 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 2.0 | 6.0 | GO:0050757 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 2.0 | 10.0 | GO:0070673 | response to interleukin-18(GO:0070673) |
| 2.0 | 5.9 | GO:0018377 | protein myristoylation(GO:0018377) |
| 2.0 | 4.0 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 2.0 | 5.9 | GO:0009183 | purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 2.0 | 5.9 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 2.0 | 3.9 | GO:0051140 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
| 2.0 | 13.8 | GO:0051026 | chiasma assembly(GO:0051026) |
| 2.0 | 3.9 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 2.0 | 7.8 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 1.9 | 5.8 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 1.9 | 52.4 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 1.9 | 7.8 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
| 1.9 | 7.7 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 1.9 | 9.6 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 1.9 | 1.9 | GO:0046641 | positive regulation of alpha-beta T cell proliferation(GO:0046641) |
| 1.9 | 28.6 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 1.9 | 36.2 | GO:0060561 | apoptotic process involved in morphogenesis(GO:0060561) |
| 1.9 | 11.4 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 1.9 | 20.9 | GO:0060004 | reflex(GO:0060004) |
| 1.9 | 1.9 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 1.9 | 151.4 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 1.9 | 34.0 | GO:2000479 | regulation of cAMP-dependent protein kinase activity(GO:2000479) |
| 1.9 | 64.1 | GO:0001895 | retina homeostasis(GO:0001895) |
| 1.9 | 50.7 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 1.9 | 30.0 | GO:0038065 | collagen-activated signaling pathway(GO:0038065) |
| 1.9 | 5.6 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 1.9 | 20.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 1.9 | 7.5 | GO:0072299 | negative regulation of glomerular mesangial cell proliferation(GO:0072125) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194) |
| 1.9 | 41.0 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 1.9 | 9.3 | GO:2000047 | regulation of cell-cell adhesion mediated by cadherin(GO:2000047) |
| 1.9 | 1.9 | GO:0051801 | cytolysis by symbiont of host cells(GO:0001897) cytolysis in other organism involved in symbiotic interaction(GO:0051801) |
| 1.9 | 1.9 | GO:0019376 | galactolipid catabolic process(GO:0019376) |
| 1.9 | 14.8 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 1.8 | 5.5 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 1.8 | 22.1 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 1.8 | 9.2 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 1.8 | 3.7 | GO:2000328 | interleukin-23-mediated signaling pathway(GO:0038155) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330) |
| 1.8 | 18.4 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 1.8 | 45.7 | GO:0048665 | neuron fate specification(GO:0048665) |
| 1.8 | 9.1 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 1.8 | 9.0 | GO:0015840 | urea transport(GO:0015840) |
| 1.8 | 26.9 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 1.8 | 14.3 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
| 1.8 | 5.4 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 1.8 | 3.6 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) |
| 1.8 | 41.1 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 1.8 | 3.6 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 1.8 | 7.1 | GO:0070255 | regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257) |
| 1.8 | 35.5 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 1.8 | 3.5 | GO:0050957 | equilibrioception(GO:0050957) |
| 1.8 | 22.9 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 1.8 | 10.6 | GO:1900424 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803) regulation of defense response to bacterium(GO:1900424) positive regulation of defense response to bacterium(GO:1900426) |
| 1.8 | 3.5 | GO:0042494 | detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
| 1.8 | 31.6 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 1.8 | 22.8 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 1.8 | 3.5 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 1.8 | 1.8 | GO:0042938 | dipeptide transport(GO:0042938) |
| 1.7 | 7.0 | GO:0008272 | sulfate transport(GO:0008272) |
| 1.7 | 5.2 | GO:0099403 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 1.7 | 14.0 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 1.7 | 3.5 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 1.7 | 19.2 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
| 1.7 | 12.1 | GO:0051934 | dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494) |
| 1.7 | 1.7 | GO:0032971 | regulation of muscle filament sliding(GO:0032971) |
| 1.7 | 17.3 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 1.7 | 8.6 | GO:0045348 | positive regulation of MHC class II biosynthetic process(GO:0045348) |
| 1.7 | 5.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 1.7 | 1.7 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 1.7 | 25.6 | GO:0005979 | regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962) |
| 1.7 | 10.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 1.7 | 13.6 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 1.7 | 10.2 | GO:1903960 | negative regulation of anion transmembrane transport(GO:1903960) |
| 1.7 | 5.1 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 1.7 | 28.5 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 1.7 | 5.0 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 1.7 | 11.7 | GO:1901563 | cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563) |
| 1.7 | 5.0 | GO:0042560 | folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 1.6 | 31.3 | GO:0072538 | T-helper 17 type immune response(GO:0072538) |
| 1.6 | 4.9 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 1.6 | 3.3 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 1.6 | 8.1 | GO:1903935 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
| 1.6 | 11.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 1.6 | 4.9 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 1.6 | 8.1 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) |
| 1.6 | 12.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 1.6 | 9.7 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 1.6 | 12.8 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
| 1.6 | 6.4 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 1.6 | 9.5 | GO:0021650 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650) |
| 1.6 | 6.4 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 1.6 | 9.5 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 1.6 | 6.3 | GO:0060737 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
| 1.6 | 6.3 | GO:2000400 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 1.6 | 3.2 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 1.6 | 14.2 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 1.6 | 4.7 | GO:0051121 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
| 1.6 | 6.3 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 1.6 | 9.4 | GO:0090625 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795) |
| 1.6 | 4.7 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 1.6 | 6.2 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 1.5 | 4.6 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 1.5 | 20.1 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 1.5 | 6.1 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 1.5 | 13.7 | GO:0033005 | positive regulation of mast cell activation(GO:0033005) |
| 1.5 | 10.6 | GO:0034086 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
| 1.5 | 25.6 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 1.5 | 15.0 | GO:0001696 | gastric acid secretion(GO:0001696) |
| 1.5 | 8.9 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 1.5 | 7.4 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 1.5 | 22.2 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 1.5 | 4.4 | GO:1900736 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 1.5 | 4.4 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 1.5 | 13.3 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 1.5 | 32.2 | GO:0097503 | sialylation(GO:0097503) |
| 1.5 | 7.3 | GO:0006265 | DNA topological change(GO:0006265) |
| 1.5 | 7.3 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 1.5 | 5.8 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 1.5 | 8.7 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 1.5 | 4.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 1.4 | 15.9 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 1.4 | 5.8 | GO:0002775 | antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) |
| 1.4 | 2.9 | GO:1902617 | response to fluoride(GO:1902617) |
| 1.4 | 53.1 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 1.4 | 12.8 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 1.4 | 7.1 | GO:0099515 | actin filament-based transport(GO:0099515) |
| 1.4 | 7.1 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 1.4 | 4.2 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 1.4 | 9.9 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 1.4 | 4.2 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 1.4 | 4.2 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 1.4 | 11.3 | GO:0006477 | protein sulfation(GO:0006477) |
| 1.4 | 11.2 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 1.4 | 22.4 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) |
| 1.4 | 4.2 | GO:0030035 | microspike assembly(GO:0030035) |
| 1.4 | 69.4 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 1.4 | 9.7 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 1.4 | 12.4 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 1.4 | 16.6 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 1.4 | 22.0 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 1.4 | 9.6 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
| 1.4 | 4.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 1.4 | 5.4 | GO:0010954 | positive regulation of protein processing(GO:0010954) |
| 1.4 | 6.8 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
| 1.3 | 6.7 | GO:0017014 | protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119) |
| 1.3 | 8.1 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 1.3 | 2.7 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 1.3 | 4.0 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 1.3 | 8.1 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 1.3 | 12.1 | GO:0006670 | sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311) |
| 1.3 | 1.3 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
| 1.3 | 2.7 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 1.3 | 4.0 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 1.3 | 4.0 | GO:0032888 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 1.3 | 17.3 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 1.3 | 37.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 1.3 | 4.0 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 1.3 | 1.3 | GO:0033504 | floor plate development(GO:0033504) |
| 1.3 | 9.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 1.3 | 2.6 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 1.3 | 1.3 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
| 1.3 | 7.9 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 1.3 | 5.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.3 | 152.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 1.3 | 7.8 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 1.3 | 5.2 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 1.3 | 14.2 | GO:0097107 | postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 1.3 | 5.1 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 1.3 | 11.6 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.3 | 21.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 1.3 | 2.6 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 1.3 | 26.6 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 1.3 | 5.1 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 1.3 | 1.3 | GO:0030222 | eosinophil differentiation(GO:0030222) |
| 1.2 | 19.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 1.2 | 1.2 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 1.2 | 12.5 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 1.2 | 10.0 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
| 1.2 | 7.5 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.2 | 2.5 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 1.2 | 3.7 | GO:0060736 | prostate gland growth(GO:0060736) |
| 1.2 | 7.4 | GO:0007000 | nucleolus organization(GO:0007000) |
| 1.2 | 5.0 | GO:0097152 | mesenchymal cell apoptotic process(GO:0097152) |
| 1.2 | 4.9 | GO:0033210 | leptin-mediated signaling pathway(GO:0033210) |
| 1.2 | 4.9 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 1.2 | 9.8 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 1.2 | 13.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 1.2 | 21.9 | GO:0006692 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 1.2 | 10.9 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 1.2 | 7.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 1.2 | 4.8 | GO:0060285 | cilium-dependent cell motility(GO:0060285) |
| 1.2 | 55.7 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 1.2 | 6.1 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 1.2 | 8.4 | GO:0044065 | regulation of respiratory system process(GO:0044065) |
| 1.2 | 4.8 | GO:0035627 | ceramide transport(GO:0035627) |
| 1.2 | 6.0 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 1.2 | 2.4 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 1.2 | 3.6 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 1.2 | 7.2 | GO:0051447 | negative regulation of meiotic cell cycle(GO:0051447) |
| 1.2 | 3.6 | GO:0061365 | positive regulation of triglyceride lipase activity(GO:0061365) |
| 1.2 | 135.8 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 1.2 | 23.8 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 1.2 | 7.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 1.2 | 1.2 | GO:0045686 | negative regulation of glial cell differentiation(GO:0045686) negative regulation of oligodendrocyte differentiation(GO:0048715) |
| 1.2 | 8.3 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 1.2 | 15.3 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 1.2 | 14.1 | GO:0048011 | neurotrophin TRK receptor signaling pathway(GO:0048011) |
| 1.2 | 11.8 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 1.2 | 1.2 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
| 1.2 | 11.7 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 1.2 | 3.5 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 1.2 | 1.2 | GO:0034124 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) |
| 1.2 | 15.1 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 1.2 | 5.8 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 1.2 | 8.1 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 1.1 | 1.1 | GO:1904124 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 1.1 | 4.6 | GO:0019323 | pentose catabolic process(GO:0019323) |
| 1.1 | 6.8 | GO:1902731 | negative regulation of chondrocyte proliferation(GO:1902731) |
| 1.1 | 20.4 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 1.1 | 38.3 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 1.1 | 2.2 | GO:0023058 | adaptation of signaling pathway(GO:0023058) |
| 1.1 | 3.3 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 1.1 | 3.3 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 1.1 | 4.5 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 1.1 | 125.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 1.1 | 3.3 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) negative regulation of urine volume(GO:0035811) |
| 1.1 | 2.2 | GO:0001554 | luteolysis(GO:0001554) |
| 1.1 | 6.5 | GO:0070571 | negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571) |
| 1.1 | 2.2 | GO:1901569 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 1.1 | 17.2 | GO:0035082 | axoneme assembly(GO:0035082) |
| 1.1 | 2.2 | GO:0071864 | regulation of cell proliferation in bone marrow(GO:0071863) positive regulation of cell proliferation in bone marrow(GO:0071864) regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290) |
| 1.1 | 6.4 | GO:0061298 | retina vasculature development in camera-type eye(GO:0061298) |
| 1.1 | 2.1 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 1.1 | 5.3 | GO:0048875 | surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875) |
| 1.1 | 7.4 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 1.1 | 13.8 | GO:0015074 | DNA integration(GO:0015074) |
| 1.1 | 15.9 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
| 1.1 | 3.2 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 1.1 | 2.1 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 1.0 | 8.4 | GO:0050881 | multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881) |
| 1.0 | 11.5 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 1.0 | 5.2 | GO:0033080 | immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 1.0 | 5.2 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 1.0 | 2.1 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 1.0 | 2.1 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 1.0 | 2.1 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347) |
| 1.0 | 7.2 | GO:0042346 | positive regulation of NF-kappaB import into nucleus(GO:0042346) |
| 1.0 | 23.7 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 1.0 | 3.1 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 1.0 | 1.0 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 1.0 | 7.2 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 1.0 | 6.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 1.0 | 4.1 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 1.0 | 4.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 1.0 | 3.0 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway(GO:0002774) |
| 1.0 | 3.0 | GO:0015847 | putrescine transport(GO:0015847) |
| 1.0 | 6.1 | GO:0071104 | response to interleukin-9(GO:0071104) |
| 1.0 | 9.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 1.0 | 8.0 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 1.0 | 3.0 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 1.0 | 4.0 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 1.0 | 4.9 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 1.0 | 4.9 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
| 1.0 | 4.9 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 1.0 | 1.9 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 1.0 | 7.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 1.0 | 10.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 1.0 | 26.1 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 1.0 | 1.9 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 1.0 | 19.1 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 1.0 | 2.9 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 1.0 | 5.7 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.9 | 5.7 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
| 0.9 | 10.4 | GO:0048485 | sympathetic nervous system development(GO:0048485) |
| 0.9 | 20.8 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.9 | 1.9 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.9 | 33.9 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.9 | 4.7 | GO:0001575 | globoside metabolic process(GO:0001575) |
| 0.9 | 1.9 | GO:0035962 | response to interleukin-13(GO:0035962) |
| 0.9 | 5.5 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.9 | 3.7 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.9 | 4.6 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.9 | 10.1 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.9 | 4.6 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.9 | 10.1 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
| 0.9 | 7.3 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.9 | 2.7 | GO:1901626 | regulation of postsynaptic membrane organization(GO:1901626) |
| 0.9 | 9.1 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 0.9 | 3.6 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.9 | 0.9 | GO:1903006 | regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 0.9 | 5.4 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.9 | 9.1 | GO:0000050 | urea cycle(GO:0000050) |
| 0.9 | 5.4 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.9 | 4.5 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.9 | 3.6 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.9 | 10.8 | GO:0040020 | regulation of meiotic nuclear division(GO:0040020) |
| 0.9 | 9.7 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.9 | 5.3 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.9 | 4.4 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.9 | 6.1 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.9 | 2.6 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
| 0.9 | 20.6 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.9 | 0.9 | GO:0050720 | interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.9 | 2.6 | GO:0044557 | relaxation of smooth muscle(GO:0044557) |
| 0.8 | 20.4 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.8 | 7.6 | GO:0048007 | antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.8 | 2.5 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.8 | 4.2 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.8 | 21.7 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.8 | 3.3 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.8 | 1.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.8 | 19.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.8 | 9.1 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.8 | 4.1 | GO:0060746 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.8 | 10.7 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.8 | 4.9 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.8 | 2.5 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 0.8 | 4.9 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.8 | 26.0 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.8 | 2.4 | GO:0018874 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 0.8 | 4.8 | GO:0017062 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.8 | 2.4 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.8 | 9.6 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.8 | 4.8 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.8 | 4.0 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.8 | 5.5 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.8 | 2.3 | GO:0045869 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) |
| 0.8 | 4.6 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
| 0.8 | 8.5 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.8 | 7.7 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.8 | 10.8 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.8 | 0.8 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.8 | 2.3 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 0.8 | 1.5 | GO:1901162 | primary amino compound biosynthetic process(GO:1901162) |
| 0.8 | 6.8 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.8 | 1.5 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.7 | 13.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.7 | 4.5 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
| 0.7 | 2.2 | GO:0052805 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
| 0.7 | 2.9 | GO:2000823 | regulation of androgen receptor activity(GO:2000823) |
| 0.7 | 2.2 | GO:0050893 | sensory processing(GO:0050893) |
| 0.7 | 11.5 | GO:0060789 | parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) hair follicle placode formation(GO:0060789) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.7 | 0.7 | GO:0032740 | positive regulation of interleukin-17 production(GO:0032740) |
| 0.7 | 5.0 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.7 | 5.0 | GO:0015871 | choline transport(GO:0015871) |
| 0.7 | 3.5 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.7 | 2.1 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 0.7 | 4.2 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.7 | 5.6 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.7 | 3.5 | GO:0071941 | nitrogen cycle metabolic process(GO:0071941) |
| 0.7 | 7.7 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.7 | 5.6 | GO:0010919 | regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.7 | 1.4 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528) |
| 0.7 | 3.5 | GO:0032095 | regulation of response to food(GO:0032095) |
| 0.7 | 2.1 | GO:0061734 | parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) |
| 0.7 | 2.0 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 0.7 | 3.4 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.7 | 8.0 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.7 | 2.7 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 0.7 | 6.0 | GO:0010640 | regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) |
| 0.7 | 1.3 | GO:0050927 | positive regulation of positive chemotaxis(GO:0050927) |
| 0.7 | 2.0 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.7 | 13.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.7 | 13.9 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.7 | 5.3 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.7 | 13.2 | GO:1900274 | regulation of phospholipase C activity(GO:1900274) |
| 0.7 | 2.0 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
| 0.7 | 23.1 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.7 | 6.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.7 | 3.9 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
| 0.7 | 9.1 | GO:0070723 | response to cholesterol(GO:0070723) |
| 0.6 | 3.9 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.6 | 15.6 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.6 | 1.3 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 0.6 | 6.5 | GO:0010996 | response to auditory stimulus(GO:0010996) |
| 0.6 | 1.9 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
| 0.6 | 0.6 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.6 | 1.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.6 | 2.6 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.6 | 0.6 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.6 | 2.6 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.6 | 6.4 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.6 | 3.2 | GO:0010044 | response to aluminum ion(GO:0010044) |
| 0.6 | 4.4 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.6 | 6.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.6 | 15.0 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.6 | 1.9 | GO:0070508 | sterol import(GO:0035376) cholesterol import(GO:0070508) |
| 0.6 | 39.4 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.6 | 6.9 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.6 | 6.2 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.6 | 6.1 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.6 | 11.6 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.6 | 4.9 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.6 | 4.8 | GO:0055090 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
| 0.6 | 2.4 | GO:0072092 | ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.6 | 5.4 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 0.6 | 35.3 | GO:0007422 | peripheral nervous system development(GO:0007422) |
| 0.6 | 6.0 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.6 | 5.9 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.6 | 3.6 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.6 | 2.3 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.6 | 1.2 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.6 | 2.9 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 0.6 | 2.9 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.6 | 8.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.6 | 1.7 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.6 | 0.6 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.6 | 0.6 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.6 | 5.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.6 | 3.9 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.6 | 5.1 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.6 | 3.9 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.6 | 1.1 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.6 | 5.6 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.6 | 2.2 | GO:0071600 | otic vesicle morphogenesis(GO:0071600) |
| 0.6 | 5.0 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.6 | 6.6 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.6 | 1.7 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.5 | 1.6 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.5 | 3.8 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.5 | 7.5 | GO:0006111 | regulation of gluconeogenesis(GO:0006111) |
| 0.5 | 3.7 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.5 | 1.1 | GO:1902713 | regulation of interferon-gamma secretion(GO:1902713) positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.5 | 4.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.5 | 8.4 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.5 | 1.6 | GO:0070269 | pyroptosis(GO:0070269) |
| 0.5 | 36.4 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
| 0.5 | 6.2 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.5 | 3.6 | GO:0035909 | aorta morphogenesis(GO:0035909) |
| 0.5 | 1.0 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.5 | 4.1 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.5 | 1.0 | GO:0046015 | regulation of transcription by glucose(GO:0046015) |
| 0.5 | 15.2 | GO:0030818 | negative regulation of cAMP biosynthetic process(GO:0030818) |
| 0.5 | 3.0 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.5 | 3.0 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.5 | 0.5 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.5 | 2.0 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 0.5 | 9.4 | GO:0097502 | mannosylation(GO:0097502) |
| 0.5 | 3.0 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.5 | 3.4 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.5 | 2.0 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.5 | 4.9 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
| 0.5 | 2.9 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.5 | 1.4 | GO:0034435 | steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435) |
| 0.5 | 1.0 | GO:0015824 | proline transport(GO:0015824) |
| 0.5 | 1.9 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.5 | 1.4 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
| 0.5 | 6.0 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.5 | 2.8 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.5 | 43.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.5 | 5.5 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.5 | 5.0 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
| 0.5 | 22.4 | GO:0030279 | negative regulation of ossification(GO:0030279) |
| 0.5 | 1.8 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.5 | 3.6 | GO:0050798 | activated T cell proliferation(GO:0050798) |
| 0.5 | 0.9 | GO:0002268 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
| 0.4 | 28.8 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.4 | 2.7 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.4 | 3.6 | GO:0006561 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 0.4 | 10.3 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.4 | 8.0 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.4 | 4.9 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.4 | 4.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.4 | 9.6 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.4 | 5.6 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.4 | 0.9 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.4 | 1.7 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.4 | 9.4 | GO:0019730 | antimicrobial humoral response(GO:0019730) |
| 0.4 | 3.4 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.4 | 3.8 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.4 | 0.4 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.4 | 5.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.4 | 6.7 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.4 | 7.9 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.4 | 2.5 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.4 | 2.5 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.4 | 6.2 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.4 | 2.5 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.4 | 0.4 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.4 | 5.3 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.4 | 3.7 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.4 | 0.4 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.4 | 7.1 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.4 | 2.7 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.4 | 25.9 | GO:0005977 | glycogen metabolic process(GO:0005977) |
| 0.4 | 1.9 | GO:0006063 | uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) |
| 0.4 | 3.1 | GO:0046320 | regulation of fatty acid oxidation(GO:0046320) |
| 0.4 | 14.0 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.4 | 6.8 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
| 0.4 | 10.9 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.4 | 2.6 | GO:0021772 | olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988) |
| 0.4 | 2.9 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.4 | 1.4 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.4 | 0.7 | GO:0071609 | chemokine (C-C motif) ligand 5 production(GO:0071609) |
| 0.4 | 3.6 | GO:0035587 | purinergic receptor signaling pathway(GO:0035587) |
| 0.4 | 0.4 | GO:1903772 | regulation of viral budding via host ESCRT complex(GO:1903772) positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.3 | 1.7 | GO:0048302 | regulation of isotype switching to IgG isotypes(GO:0048302) |
| 0.3 | 0.7 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.3 | 4.8 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.3 | 4.1 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
| 0.3 | 0.7 | GO:0001826 | inner cell mass cell differentiation(GO:0001826) |
| 0.3 | 1.7 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.3 | 3.7 | GO:0048290 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) |
| 0.3 | 4.6 | GO:0098868 | bone growth(GO:0098868) |
| 0.3 | 1.3 | GO:0039692 | single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) |
| 0.3 | 1.6 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.3 | 7.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.3 | 2.6 | GO:0001945 | lymph vessel development(GO:0001945) |
| 0.3 | 0.9 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.3 | 1.5 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
| 0.3 | 35.5 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
| 0.3 | 3.0 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.3 | 0.9 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.3 | 3.6 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.3 | 152.3 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.3 | 0.6 | GO:0007500 | mesodermal cell fate determination(GO:0007500) |
| 0.3 | 4.5 | GO:0048753 | pigment granule organization(GO:0048753) |
| 0.3 | 8.0 | GO:0032945 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.3 | 0.6 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
| 0.3 | 1.7 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.3 | 0.6 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.3 | 1.9 | GO:0010744 | positive regulation of macrophage derived foam cell differentiation(GO:0010744) |
| 0.3 | 1.9 | GO:0061430 | bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) |
| 0.3 | 3.5 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.3 | 1.3 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.3 | 2.0 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.3 | 2.0 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.3 | 1.8 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.3 | 1.0 | GO:0036037 | CD8-positive, alpha-beta T cell activation(GO:0036037) |
| 0.3 | 3.0 | GO:0006067 | ethanol metabolic process(GO:0006067) |
| 0.2 | 0.7 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.2 | 4.9 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
| 0.2 | 1.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.7 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.2 | 0.7 | GO:1990426 | homologous recombination-dependent replication fork processing(GO:1990426) |
| 0.2 | 0.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 0.5 | GO:0072132 | mesenchyme morphogenesis(GO:0072132) |
| 0.2 | 3.0 | GO:0050718 | positive regulation of interleukin-1 beta secretion(GO:0050718) |
| 0.2 | 0.9 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.2 | 1.5 | GO:0021904 | dorsal/ventral neural tube patterning(GO:0021904) |
| 0.2 | 0.4 | GO:0048840 | otolith development(GO:0048840) |
| 0.2 | 0.4 | GO:0002018 | renin-angiotensin regulation of aldosterone production(GO:0002018) |
| 0.2 | 1.7 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.2 | 1.4 | GO:0047496 | vesicle transport along microtubule(GO:0047496) |
| 0.2 | 2.4 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.2 | 1.0 | GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.2 | 0.8 | GO:0043201 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
| 0.2 | 3.4 | GO:0009880 | embryonic pattern specification(GO:0009880) |
| 0.2 | 0.8 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.2 | 1.8 | GO:1901203 | positive regulation of extracellular matrix assembly(GO:1901203) |
| 0.2 | 1.4 | GO:0032366 | intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367) |
| 0.2 | 1.4 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.2 | 1.0 | GO:0045655 | regulation of monocyte differentiation(GO:0045655) |
| 0.2 | 1.5 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.2 | 1.4 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.2 | 2.3 | GO:0051255 | spindle midzone assembly(GO:0051255) |
| 0.2 | 3.0 | GO:0003310 | pancreatic A cell differentiation(GO:0003310) pancreatic A cell development(GO:0003322) |
| 0.2 | 0.7 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.2 | 0.3 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.2 | 1.5 | GO:0050691 | regulation of defense response to virus by host(GO:0050691) |
| 0.2 | 0.2 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 0.2 | 0.6 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.2 | 1.6 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.2 | 0.5 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.1 | 0.1 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010) |
| 0.1 | 12.8 | GO:0048515 | spermatid differentiation(GO:0048515) |
| 0.1 | 1.0 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.1 | 1.1 | GO:0015919 | peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046) |
| 0.1 | 0.5 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.1 | 0.9 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 0.3 | GO:0035608 | protein deglutamylation(GO:0035608) |
| 0.1 | 0.6 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 1.8 | GO:0018023 | peptidyl-lysine trimethylation(GO:0018023) |
| 0.1 | 1.0 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 3.4 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.1 | 0.5 | GO:0042220 | response to cocaine(GO:0042220) |
| 0.1 | 0.5 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 10.8 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 0.6 | GO:0014911 | positive regulation of smooth muscle cell migration(GO:0014911) |
| 0.1 | 2.2 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.1 | 2.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 1.0 | GO:0009953 | dorsal/ventral pattern formation(GO:0009953) |
| 0.1 | 0.4 | GO:0001773 | myeloid dendritic cell activation(GO:0001773) |
| 0.1 | 0.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.3 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.1 | 0.5 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.1 | 0.6 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.1 | 0.2 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) serotonin receptor signaling pathway(GO:0007210) |
| 0.1 | 0.2 | GO:0002363 | alpha-beta T cell lineage commitment(GO:0002363) |
| 0.1 | 0.3 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.0 | 1.9 | GO:0018022 | peptidyl-lysine methylation(GO:0018022) |
| 0.0 | 0.5 | GO:0009437 | carnitine metabolic process(GO:0009437) |
| 0.0 | 0.4 | GO:0045123 | cellular extravasation(GO:0045123) |
| 0.0 | 0.4 | GO:0003373 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.0 | 0.3 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0070528 | protein kinase C signaling(GO:0070528) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 19.1 | 76.6 | GO:0070695 | FHF complex(GO:0070695) |
| 14.6 | 87.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 12.8 | 102.2 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 12.3 | 98.3 | GO:0045179 | apical cortex(GO:0045179) |
| 11.3 | 90.6 | GO:0035976 | AP1 complex(GO:0035976) |
| 11.3 | 90.4 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 11.1 | 44.3 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 11.0 | 43.9 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 10.0 | 10.0 | GO:1902710 | GABA receptor complex(GO:1902710) |
| 9.9 | 29.8 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 9.9 | 29.6 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 9.4 | 75.6 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 8.7 | 69.4 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 8.5 | 8.5 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 8.0 | 32.0 | GO:0071546 | pi-body(GO:0071546) |
| 7.3 | 145.9 | GO:0033270 | paranode region of axon(GO:0033270) |
| 7.2 | 93.5 | GO:0042583 | chromaffin granule(GO:0042583) |
| 7.0 | 77.3 | GO:0033010 | paranodal junction(GO:0033010) |
| 6.5 | 39.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 6.1 | 30.7 | GO:0036128 | CatSper complex(GO:0036128) |
| 6.1 | 6.1 | GO:0097449 | glial cell projection(GO:0097386) astrocyte projection(GO:0097449) |
| 6.1 | 18.3 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 6.1 | 30.5 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 6.0 | 24.2 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 6.0 | 18.0 | GO:0032426 | stereocilium tip(GO:0032426) |
| 5.2 | 15.7 | GO:0070701 | mucus layer(GO:0070701) |
| 5.2 | 72.1 | GO:0097433 | dense body(GO:0097433) |
| 5.1 | 81.8 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 5.1 | 127.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 5.0 | 15.0 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 4.8 | 4.8 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 4.8 | 23.8 | GO:1990031 | pinceau fiber(GO:1990031) |
| 4.7 | 14.0 | GO:0071756 | IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756) |
| 4.6 | 13.9 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 4.6 | 27.4 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 4.6 | 45.6 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 4.5 | 9.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 4.5 | 58.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 4.4 | 17.6 | GO:1990879 | CST complex(GO:1990879) |
| 4.4 | 60.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 4.3 | 43.0 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 4.3 | 25.6 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 4.2 | 8.5 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 4.2 | 12.6 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 4.2 | 20.8 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 4.1 | 231.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 4.0 | 24.0 | GO:0001940 | male pronucleus(GO:0001940) |
| 3.9 | 19.7 | GO:0032280 | symmetric synapse(GO:0032280) |
| 3.9 | 23.4 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 3.9 | 19.3 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 3.8 | 23.0 | GO:0045298 | tubulin complex(GO:0045298) |
| 3.8 | 71.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 3.8 | 18.8 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 3.7 | 29.7 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 3.6 | 14.3 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 3.5 | 31.4 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 3.5 | 76.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 3.4 | 10.2 | GO:0032009 | early phagosome(GO:0032009) |
| 3.3 | 9.9 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 3.2 | 18.9 | GO:0030008 | TRAPP complex(GO:0030008) |
| 3.1 | 15.6 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 3.1 | 9.3 | GO:0098536 | deuterosome(GO:0098536) |
| 3.0 | 21.1 | GO:0032021 | NELF complex(GO:0032021) |
| 3.0 | 35.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 3.0 | 8.9 | GO:0032437 | cuticular plate(GO:0032437) |
| 2.9 | 17.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 2.9 | 125.6 | GO:0031430 | M band(GO:0031430) |
| 2.9 | 54.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 2.9 | 37.2 | GO:0031045 | dense core granule(GO:0031045) |
| 2.8 | 14.2 | GO:0032807 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 2.8 | 19.9 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 2.8 | 31.1 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 2.8 | 5.7 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 2.8 | 11.1 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 2.8 | 36.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 2.8 | 16.7 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 2.8 | 33.3 | GO:0097427 | microtubule bundle(GO:0097427) |
| 2.7 | 22.0 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 2.7 | 2.7 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 2.7 | 67.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 2.7 | 45.7 | GO:0042627 | chylomicron(GO:0042627) |
| 2.7 | 10.6 | GO:0044327 | dendritic spine head(GO:0044327) |
| 2.6 | 18.4 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 2.6 | 7.9 | GO:0036398 | TCR signalosome(GO:0036398) |
| 2.6 | 10.4 | GO:0031310 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
| 2.6 | 13.0 | GO:0089701 | U2AF(GO:0089701) |
| 2.6 | 217.7 | GO:0034707 | chloride channel complex(GO:0034707) |
| 2.6 | 43.9 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 2.5 | 60.5 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 2.5 | 101.0 | GO:0001533 | cornified envelope(GO:0001533) |
| 2.4 | 41.6 | GO:0005861 | troponin complex(GO:0005861) |
| 2.4 | 9.8 | GO:0030897 | HOPS complex(GO:0030897) |
| 2.4 | 77.9 | GO:0043235 | receptor complex(GO:0043235) |
| 2.4 | 48.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 2.4 | 58.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 2.4 | 21.7 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 2.4 | 12.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 2.4 | 49.8 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 2.4 | 68.8 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 2.4 | 16.6 | GO:1990745 | EARP complex(GO:1990745) |
| 2.4 | 172.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 2.4 | 7.1 | GO:0032116 | SMC loading complex(GO:0032116) |
| 2.3 | 7.0 | GO:0043293 | apoptosome(GO:0043293) |
| 2.3 | 16.2 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 2.3 | 6.9 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 2.2 | 8.9 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 2.2 | 31.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 2.2 | 11.0 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 2.2 | 10.9 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 2.2 | 39.2 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 2.2 | 30.1 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 2.1 | 14.9 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 2.1 | 31.9 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 2.1 | 4.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 2.1 | 6.3 | GO:0005760 | gamma DNA polymerase complex(GO:0005760) |
| 2.1 | 45.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 2.1 | 10.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 2.1 | 88.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 2.0 | 18.4 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 2.0 | 6.0 | GO:1990812 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 2.0 | 12.0 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 1.9 | 5.8 | GO:0000801 | central element(GO:0000801) |
| 1.9 | 19.4 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 1.9 | 15.4 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 1.9 | 11.3 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 1.9 | 132.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 1.9 | 7.4 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 1.8 | 3.7 | GO:1990635 | proximal dendrite(GO:1990635) |
| 1.8 | 20.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.8 | 25.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 1.8 | 18.1 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 1.8 | 30.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 1.8 | 10.8 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 1.8 | 18.0 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 1.8 | 8.9 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 1.8 | 24.9 | GO:0043083 | synaptic cleft(GO:0043083) |
| 1.8 | 140.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 1.7 | 26.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 1.7 | 7.0 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 1.7 | 50.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 1.7 | 17.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 1.7 | 13.8 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 1.7 | 25.6 | GO:0044447 | axoneme part(GO:0044447) |
| 1.7 | 38.2 | GO:0031528 | microvillus membrane(GO:0031528) |
| 1.7 | 3.3 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 1.7 | 82.6 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
| 1.6 | 100.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 1.6 | 3.2 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 1.6 | 11.3 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 1.6 | 8.0 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 1.6 | 3.2 | GO:1990393 | 3M complex(GO:1990393) |
| 1.6 | 6.4 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 1.6 | 9.6 | GO:0032010 | phagolysosome(GO:0032010) |
| 1.6 | 4.8 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 1.6 | 8.0 | GO:0005713 | recombination nodule(GO:0005713) |
| 1.6 | 11.1 | GO:0005921 | gap junction(GO:0005921) |
| 1.6 | 17.3 | GO:0042587 | glycogen granule(GO:0042587) |
| 1.6 | 67.0 | GO:0005902 | microvillus(GO:0005902) |
| 1.5 | 37.1 | GO:0008305 | integrin complex(GO:0008305) |
| 1.5 | 7.7 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 1.5 | 29.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 1.5 | 10.6 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 1.5 | 4.5 | GO:0044609 | DBIRD complex(GO:0044609) |
| 1.5 | 7.5 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 1.5 | 68.1 | GO:0097546 | ciliary base(GO:0097546) |
| 1.5 | 50.1 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 1.5 | 27.9 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 1.5 | 4.4 | GO:0016013 | syntrophin complex(GO:0016013) |
| 1.4 | 13.0 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 1.4 | 22.9 | GO:0005652 | nuclear lamina(GO:0005652) |
| 1.4 | 5.7 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 1.4 | 18.5 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.4 | 2.8 | GO:0001939 | female pronucleus(GO:0001939) |
| 1.4 | 5.6 | GO:0044279 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 1.4 | 78.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 1.3 | 2.7 | GO:0043291 | RAVE complex(GO:0043291) |
| 1.3 | 4.0 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 1.3 | 6.7 | GO:0032449 | CBM complex(GO:0032449) |
| 1.3 | 21.2 | GO:0005922 | connexon complex(GO:0005922) |
| 1.3 | 43.0 | GO:0042629 | mast cell granule(GO:0042629) |
| 1.3 | 131.0 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 1.3 | 6.5 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 1.3 | 16.7 | GO:0035579 | specific granule membrane(GO:0035579) |
| 1.3 | 7.6 | GO:0033179 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 1.2 | 3.7 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 1.2 | 33.9 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 1.2 | 3.6 | GO:0016938 | kinesin I complex(GO:0016938) |
| 1.2 | 7.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 1.2 | 3.6 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 1.2 | 14.4 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 1.2 | 6.0 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 1.2 | 7.1 | GO:0070545 | PeBoW complex(GO:0070545) |
| 1.2 | 2.4 | GO:0030430 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 1.2 | 13.0 | GO:0035102 | PRC1 complex(GO:0035102) |
| 1.2 | 6.9 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 1.1 | 125.0 | GO:0043204 | perikaryon(GO:0043204) |
| 1.1 | 7.9 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 1.1 | 14.7 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.1 | 23.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 1.1 | 6.7 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 1.1 | 3.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 1.1 | 152.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 1.1 | 14.2 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 1.1 | 6.5 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 1.1 | 159.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 1.1 | 37.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 1.0 | 7.3 | GO:0043679 | axon terminus(GO:0043679) |
| 1.0 | 9.3 | GO:0070652 | HAUS complex(GO:0070652) |
| 1.0 | 183.8 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 1.0 | 242.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 1.0 | 14.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 1.0 | 96.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 1.0 | 33.7 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 1.0 | 19.4 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 1.0 | 6.8 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.9 | 38.9 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.9 | 7.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.9 | 2.7 | GO:0034657 | GID complex(GO:0034657) |
| 0.9 | 8.1 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
| 0.9 | 33.1 | GO:0030175 | filopodium(GO:0030175) |
| 0.9 | 8.1 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.9 | 14.3 | GO:0000800 | lateral element(GO:0000800) |
| 0.9 | 7.1 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.9 | 4.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.9 | 29.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.9 | 4.3 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.9 | 6.8 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.8 | 4.2 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.8 | 1.7 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.8 | 4.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.8 | 20.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.8 | 2.5 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.8 | 36.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.8 | 3.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.8 | 17.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.8 | 107.5 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.8 | 2.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.8 | 42.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.7 | 12.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.7 | 2.9 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.7 | 2.9 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.7 | 2.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.7 | 2.8 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.7 | 2.8 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.7 | 3.5 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.7 | 29.5 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.7 | 12.9 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.7 | 4.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.7 | 4.0 | GO:0000243 | commitment complex(GO:0000243) |
| 0.7 | 4.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.7 | 20.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.6 | 39.5 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.6 | 29.7 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.6 | 2.5 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.6 | 12.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.6 | 5.5 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.6 | 9.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.6 | 1.8 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.6 | 61.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.6 | 6.9 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.6 | 76.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.5 | 7.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.5 | 2.7 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.5 | 15.6 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.5 | 1.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.5 | 7.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.5 | 4.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.5 | 2.0 | GO:0035363 | histone locus body(GO:0035363) |
| 0.5 | 598.1 | GO:0005615 | extracellular space(GO:0005615) |
| 0.5 | 4.9 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.5 | 4.7 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.5 | 0.9 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.4 | 9.4 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
| 0.4 | 1694.1 | GO:0031224 | intrinsic component of membrane(GO:0031224) |
| 0.4 | 1.8 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.4 | 3.4 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.4 | 1.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.4 | 2.3 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.4 | 9.3 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.4 | 1.8 | GO:0045180 | basal cortex(GO:0045180) |
| 0.3 | 4.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.3 | 0.6 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.3 | 0.9 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.3 | 2.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.3 | 13.3 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.3 | 3.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.3 | 2.6 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 2.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.2 | 0.9 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.2 | 2.2 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.2 | 10.4 | GO:0030424 | axon(GO:0030424) |
| 0.1 | 0.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 1.4 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.5 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 0.7 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.9 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 2.7 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 0.4 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
| 0.1 | 0.3 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.1 | 1.8 | GO:0000791 | euchromatin(GO:0000791) |
| 0.1 | 0.4 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.1 | 0.7 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 7.2 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.5 | GO:0035869 | ciliary transition zone(GO:0035869) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 17.0 | 50.9 | GO:0015389 | pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 16.0 | 64.0 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 15.6 | 46.8 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 14.3 | 171.8 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 14.3 | 57.2 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 12.4 | 74.2 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 12.4 | 37.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 11.5 | 46.0 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 11.0 | 154.6 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 10.8 | 43.0 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) |
| 10.6 | 31.9 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 10.4 | 41.6 | GO:0061769 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 10.0 | 30.1 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 9.8 | 39.0 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 9.7 | 29.1 | GO:0047977 | hepoxilin-epoxide hydrolase activity(GO:0047977) |
| 9.5 | 28.6 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 9.4 | 28.3 | GO:0004040 | amidase activity(GO:0004040) |
| 9.4 | 28.2 | GO:0036055 | protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697) |
| 9.3 | 18.7 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 9.3 | 18.6 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 9.2 | 36.8 | GO:0004341 | gluconolactonase activity(GO:0004341) |
| 8.9 | 26.8 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 8.9 | 80.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 8.8 | 61.6 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 8.6 | 25.9 | GO:0031696 | alpha-2C adrenergic receptor binding(GO:0031696) |
| 8.4 | 8.4 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 8.3 | 8.3 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 8.3 | 33.2 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 8.2 | 65.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 7.9 | 31.5 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 7.7 | 30.7 | GO:0004513 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 7.3 | 29.3 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 7.3 | 43.6 | GO:0016416 | O-palmitoyltransferase activity(GO:0016416) |
| 7.2 | 21.5 | GO:0004507 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
| 7.1 | 28.3 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
| 7.0 | 42.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 7.0 | 105.2 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 6.9 | 48.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 6.9 | 27.7 | GO:0008832 | dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567) |
| 6.6 | 329.2 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 6.5 | 26.0 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 6.5 | 90.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 6.3 | 18.9 | GO:0008431 | vitamin E binding(GO:0008431) |
| 6.3 | 18.8 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 6.1 | 24.4 | GO:0018271 | biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271) |
| 6.1 | 42.4 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 6.0 | 18.1 | GO:0001601 | peptide YY receptor activity(GO:0001601) |
| 6.0 | 12.0 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 6.0 | 24.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 6.0 | 107.6 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 5.9 | 17.8 | GO:0008969 | phosphohistidine phosphatase activity(GO:0008969) |
| 5.8 | 17.5 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 5.8 | 23.3 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 5.8 | 52.2 | GO:0043426 | MRF binding(GO:0043426) |
| 5.8 | 23.1 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 5.8 | 28.9 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 5.7 | 17.2 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 5.7 | 17.1 | GO:0034046 | poly(G) binding(GO:0034046) |
| 5.7 | 17.1 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 5.6 | 33.8 | GO:0030172 | troponin C binding(GO:0030172) |
| 5.6 | 22.5 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 5.6 | 44.7 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 5.6 | 27.9 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 5.5 | 66.1 | GO:0016594 | glycine binding(GO:0016594) |
| 5.4 | 16.3 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 5.4 | 48.9 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 5.4 | 21.7 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 5.4 | 16.2 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 5.4 | 16.2 | GO:0070052 | collagen V binding(GO:0070052) |
| 5.4 | 21.5 | GO:0047708 | biotinidase activity(GO:0047708) |
| 5.4 | 32.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 5.3 | 26.5 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 5.2 | 20.8 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
| 5.2 | 15.5 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 5.1 | 20.6 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 5.1 | 10.3 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 5.1 | 15.2 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 5.0 | 49.9 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 5.0 | 20.0 | GO:0016495 | C-X3-C chemokine receptor activity(GO:0016495) |
| 5.0 | 14.9 | GO:0032093 | SAM domain binding(GO:0032093) |
| 4.9 | 19.4 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 4.8 | 43.6 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 4.8 | 76.9 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 4.8 | 28.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 4.8 | 81.3 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 4.6 | 9.3 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
| 4.6 | 23.0 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 4.6 | 36.7 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 4.5 | 13.6 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 4.5 | 18.1 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 4.5 | 27.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 4.5 | 67.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 4.5 | 36.0 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 4.5 | 26.9 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 4.5 | 13.4 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 4.5 | 89.3 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 4.5 | 102.4 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 4.4 | 13.2 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 4.4 | 17.4 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 4.4 | 61.0 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 4.3 | 30.4 | GO:0005333 | norepinephrine transmembrane transporter activity(GO:0005333) |
| 4.3 | 17.3 | GO:0032810 | sterol response element binding(GO:0032810) |
| 4.3 | 21.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 4.3 | 12.9 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 4.3 | 51.6 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 4.3 | 25.8 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 4.3 | 17.0 | GO:0031433 | telethonin binding(GO:0031433) |
| 4.2 | 33.3 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 4.1 | 45.5 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 4.1 | 16.4 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 4.1 | 32.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 4.1 | 20.3 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 4.1 | 20.3 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 4.1 | 12.2 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) |
| 4.0 | 36.3 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 4.0 | 20.1 | GO:0050436 | microfibril binding(GO:0050436) |
| 4.0 | 28.0 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 4.0 | 19.9 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 4.0 | 4.0 | GO:0047787 | delta4-3-oxosteroid 5beta-reductase activity(GO:0047787) |
| 4.0 | 35.6 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 4.0 | 98.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 3.9 | 31.5 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 3.9 | 55.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 3.9 | 15.7 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 3.9 | 19.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 3.9 | 23.4 | GO:0008142 | oxysterol binding(GO:0008142) |
| 3.9 | 7.8 | GO:0004651 | polynucleotide 5'-phosphatase activity(GO:0004651) |
| 3.9 | 85.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 3.9 | 54.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 3.9 | 88.8 | GO:0031005 | filamin binding(GO:0031005) |
| 3.9 | 50.1 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 3.9 | 7.7 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 3.8 | 42.3 | GO:0033691 | sialic acid binding(GO:0033691) |
| 3.8 | 95.9 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 3.8 | 19.0 | GO:0008948 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 3.8 | 18.9 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 3.7 | 48.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 3.7 | 100.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 3.7 | 22.2 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 3.7 | 37.0 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 3.7 | 14.7 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 3.7 | 102.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 3.7 | 11.0 | GO:0046577 | long-chain-alcohol oxidase activity(GO:0046577) |
| 3.7 | 25.6 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 3.6 | 7.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 3.6 | 14.4 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 3.6 | 10.8 | GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584) |
| 3.6 | 10.8 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 3.6 | 56.9 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 3.5 | 24.7 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 3.5 | 17.6 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 3.5 | 14.0 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 3.5 | 34.9 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 3.5 | 20.9 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 3.5 | 10.4 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 3.5 | 17.3 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 3.5 | 13.9 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 3.5 | 13.8 | GO:0001855 | complement component C4b binding(GO:0001855) |
| 3.5 | 65.6 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 3.4 | 10.3 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 3.4 | 10.2 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 3.4 | 10.2 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 3.4 | 16.8 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 3.3 | 10.0 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 3.3 | 13.4 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 3.3 | 23.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 3.3 | 10.0 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 3.3 | 16.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 3.3 | 26.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 3.3 | 9.8 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 3.3 | 29.4 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 3.3 | 22.8 | GO:0005499 | vitamin D binding(GO:0005499) |
| 3.3 | 13.0 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 3.3 | 13.0 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 3.3 | 13.0 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 3.2 | 199.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 3.2 | 22.2 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 3.1 | 22.0 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 3.1 | 9.4 | GO:0016422 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 3.1 | 28.0 | GO:0034711 | inhibin binding(GO:0034711) |
| 3.1 | 52.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 3.1 | 3.1 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 3.1 | 15.4 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 3.1 | 58.4 | GO:0038191 | neuropilin binding(GO:0038191) |
| 3.0 | 33.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 3.0 | 21.2 | GO:0000182 | rDNA binding(GO:0000182) |
| 3.0 | 12.1 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 3.0 | 11.9 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 3.0 | 17.9 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 3.0 | 11.9 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 3.0 | 8.9 | GO:0003826 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 2.9 | 103.2 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 2.9 | 41.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 2.9 | 317.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 2.9 | 143.8 | GO:0030552 | cAMP binding(GO:0030552) |
| 2.9 | 14.6 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 2.9 | 8.8 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 2.9 | 63.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 2.8 | 53.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 2.8 | 28.3 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 2.8 | 8.5 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 2.8 | 16.9 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 2.8 | 16.8 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 2.8 | 14.0 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 2.8 | 8.4 | GO:0001007 | transcription factor activity, core RNA polymerase III binding(GO:0000995) transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) |
| 2.8 | 33.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 2.8 | 13.9 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 2.8 | 8.3 | GO:0035473 | lipase binding(GO:0035473) |
| 2.8 | 8.3 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 2.8 | 13.8 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 2.7 | 8.2 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 2.7 | 8.2 | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 2.7 | 2.7 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 2.7 | 8.1 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 2.7 | 16.2 | GO:0051373 | FATZ binding(GO:0051373) |
| 2.7 | 24.3 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 2.7 | 18.9 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 2.7 | 2.7 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 2.7 | 26.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 2.7 | 18.6 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 2.7 | 8.0 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 2.7 | 10.6 | GO:0052595 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 2.7 | 15.9 | GO:0004359 | glutaminase activity(GO:0004359) |
| 2.6 | 7.9 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 2.6 | 28.9 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 2.6 | 7.9 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 2.6 | 5.2 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 2.6 | 13.1 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 2.6 | 7.8 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 2.6 | 10.3 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 2.6 | 28.2 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 2.5 | 5.1 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 2.5 | 20.4 | GO:0038064 | collagen receptor activity(GO:0038064) |
| 2.5 | 7.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 2.5 | 45.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 2.5 | 27.7 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 2.5 | 10.0 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 2.5 | 10.0 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 2.5 | 10.0 | GO:0098960 | postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 2.5 | 7.5 | GO:0004915 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) ciliary neurotrophic factor binding(GO:0070119) |
| 2.5 | 42.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 2.5 | 7.5 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 2.5 | 7.4 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 2.5 | 27.3 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589) |
| 2.5 | 19.7 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 2.5 | 7.4 | GO:0004336 | galactosylceramidase activity(GO:0004336) |
| 2.5 | 9.9 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 2.4 | 7.3 | GO:0003916 | DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917) |
| 2.4 | 9.6 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
| 2.4 | 31.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 2.4 | 16.9 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 2.4 | 2.4 | GO:0001034 | RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
| 2.4 | 45.5 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 2.4 | 26.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 2.4 | 4.7 | GO:0051120 | hepoxilin A3 synthase activity(GO:0051120) |
| 2.3 | 14.0 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 2.3 | 9.3 | GO:0002046 | opsin binding(GO:0002046) |
| 2.3 | 7.0 | GO:0035375 | zymogen binding(GO:0035375) |
| 2.3 | 14.0 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 2.3 | 11.5 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 2.3 | 9.2 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 2.3 | 18.3 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 2.3 | 15.9 | GO:0004797 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 2.3 | 63.4 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 2.2 | 6.7 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 2.2 | 13.5 | GO:0022821 | potassium ion antiporter activity(GO:0022821) |
| 2.2 | 35.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 2.2 | 8.9 | GO:0061513 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 2.2 | 6.7 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 2.2 | 11.0 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 2.2 | 13.2 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 2.2 | 13.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 2.2 | 11.0 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 2.2 | 8.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 2.2 | 8.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 2.2 | 10.8 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 2.2 | 6.5 | GO:0043121 | neurotrophin receptor activity(GO:0005030) neurotrophin binding(GO:0043121) |
| 2.2 | 25.9 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 2.1 | 8.5 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 2.1 | 10.7 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 2.1 | 6.4 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 2.1 | 4.2 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 2.1 | 116.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 2.1 | 6.3 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 2.1 | 10.5 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 2.1 | 6.2 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 2.1 | 29.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 2.0 | 2.0 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 2.0 | 22.5 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 2.0 | 6.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 2.0 | 2.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 2.0 | 16.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 2.0 | 12.0 | GO:0000404 | heteroduplex DNA loop binding(GO:0000404) |
| 2.0 | 15.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 2.0 | 3.9 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 2.0 | 15.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 1.9 | 233.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 1.9 | 23.2 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 1.9 | 7.7 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 1.9 | 7.7 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 1.9 | 5.7 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 1.9 | 38.3 | GO:0044548 | S100 protein binding(GO:0044548) |
| 1.9 | 1.9 | GO:0015116 | sulfate transmembrane transporter activity(GO:0015116) |
| 1.9 | 32.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 1.9 | 13.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 1.9 | 7.5 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
| 1.9 | 14.9 | GO:0015232 | heme transporter activity(GO:0015232) |
| 1.8 | 9.2 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 1.8 | 9.2 | GO:0010857 | calcium-dependent protein kinase activity(GO:0010857) |
| 1.8 | 38.1 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 1.8 | 508.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 1.8 | 32.4 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 1.8 | 124.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 1.8 | 7.2 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 1.8 | 7.2 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 1.8 | 7.1 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 1.8 | 21.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 1.8 | 14.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 1.8 | 21.0 | GO:0031014 | troponin T binding(GO:0031014) |
| 1.7 | 15.6 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 1.7 | 53.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 1.7 | 13.8 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 1.7 | 10.3 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 1.7 | 6.8 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 1.7 | 44.1 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 1.7 | 10.1 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 1.7 | 20.1 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 1.7 | 11.7 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 1.7 | 8.4 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 1.7 | 5.0 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 1.7 | 199.0 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 1.7 | 8.3 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 1.7 | 102.7 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 1.6 | 47.8 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 1.6 | 6.6 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 1.6 | 13.2 | GO:0043274 | phospholipase binding(GO:0043274) |
| 1.6 | 24.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 1.6 | 13.0 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 1.6 | 19.4 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 1.6 | 51.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 1.6 | 14.4 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 1.6 | 48.0 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 1.6 | 9.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 1.6 | 8.0 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 1.6 | 4.8 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 1.6 | 4.8 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 1.6 | 3.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 1.6 | 17.5 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 1.6 | 15.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 1.6 | 33.3 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 1.6 | 9.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 1.6 | 6.3 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 1.6 | 7.9 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 1.6 | 37.4 | GO:0030506 | ankyrin binding(GO:0030506) |
| 1.6 | 3.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 1.5 | 41.8 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 1.5 | 61.7 | GO:0070840 | dynein complex binding(GO:0070840) |
| 1.5 | 7.7 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 1.5 | 15.3 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 1.5 | 16.8 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 1.5 | 10.6 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 1.5 | 22.6 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 1.5 | 26.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 1.5 | 17.9 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 1.5 | 4.5 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 1.5 | 33.6 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 1.5 | 5.8 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 1.4 | 44.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 1.4 | 5.8 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 1.4 | 5.8 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 1.4 | 12.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 1.4 | 7.1 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 1.4 | 11.3 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 1.4 | 19.8 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 1.4 | 4.2 | GO:0031711 | angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711) |
| 1.4 | 7.0 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 1.4 | 22.4 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 1.4 | 7.0 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 1.4 | 22.2 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 1.4 | 37.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 1.4 | 5.5 | GO:1904492 | Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493) |
| 1.4 | 4.1 | GO:0005135 | erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135) |
| 1.4 | 13.6 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
| 1.4 | 4.1 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 1.4 | 4.1 | GO:0000248 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 1.4 | 9.5 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 1.4 | 2.7 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) |
| 1.3 | 35.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 1.3 | 20.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 1.3 | 16.1 | GO:0031432 | titin binding(GO:0031432) |
| 1.3 | 6.6 | GO:0004803 | transposase activity(GO:0004803) |
| 1.3 | 10.5 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 1.3 | 15.8 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 1.3 | 3.9 | GO:0015265 | urea channel activity(GO:0015265) |
| 1.3 | 6.5 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 1.3 | 3.9 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 1.3 | 3.9 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 1.3 | 2.6 | GO:0055102 | lipase inhibitor activity(GO:0055102) |
| 1.3 | 3.8 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 1.3 | 16.6 | GO:0005372 | water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250) |
| 1.3 | 29.1 | GO:0022839 | ion gated channel activity(GO:0022839) |
| 1.3 | 7.6 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 1.3 | 7.5 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 1.3 | 6.3 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 1.2 | 7.5 | GO:0003796 | lysozyme activity(GO:0003796) |
| 1.2 | 1.2 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 1.2 | 3.7 | GO:0036080 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 1.2 | 11.1 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 1.2 | 11.0 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 1.2 | 1.2 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 1.2 | 3.7 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 1.2 | 4.9 | GO:0097001 | ceramide binding(GO:0097001) |
| 1.2 | 3.6 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 1.2 | 8.4 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 1.2 | 4.8 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 1.2 | 4.8 | GO:0070728 | leucine binding(GO:0070728) |
| 1.2 | 10.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 1.2 | 123.5 | GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) |
| 1.2 | 7.1 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 1.2 | 15.4 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 1.2 | 29.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 1.1 | 13.7 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 1.1 | 8.0 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 1.1 | 4.5 | GO:0016426 | tRNA (adenine) methyltransferase activity(GO:0016426) |
| 1.1 | 28.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 1.1 | 25.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 1.1 | 3.4 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 1.1 | 6.7 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 1.1 | 101.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 1.1 | 3.3 | GO:0004750 | ribulose-phosphate 3-epimerase activity(GO:0004750) |
| 1.1 | 2.2 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 1.1 | 6.6 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 1.1 | 14.3 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 1.1 | 14.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 1.1 | 7.6 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 1.1 | 7.6 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 1.1 | 2.2 | GO:0050051 | leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 1.1 | 4.3 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 1.1 | 3.2 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 1.1 | 7.5 | GO:0039706 | co-receptor binding(GO:0039706) |
| 1.1 | 2.1 | GO:0016406 | carnitine O-acyltransferase activity(GO:0016406) |
| 1.1 | 45.1 | GO:0043621 | protein self-association(GO:0043621) |
| 1.1 | 3.2 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 1.1 | 3.2 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 1.1 | 10.7 | GO:0008061 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
| 1.1 | 17.0 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 1.1 | 8.5 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 1.1 | 5.3 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 1.1 | 13.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.0 | 5.2 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740) |
| 1.0 | 16.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 1.0 | 13.4 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 1.0 | 3.1 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 1.0 | 3.1 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 1.0 | 3.0 | GO:0015489 | polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489) |
| 1.0 | 3.0 | GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 1.0 | 7.0 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 1.0 | 12.0 | GO:0051184 | cofactor transporter activity(GO:0051184) |
| 1.0 | 4.0 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 1.0 | 4.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 1.0 | 6.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 1.0 | 3.0 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.0 | 5.9 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 1.0 | 2.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 1.0 | 40.1 | GO:0008009 | chemokine activity(GO:0008009) |
| 1.0 | 4.9 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 1.0 | 3.9 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 1.0 | 4.9 | GO:0016936 | galactoside binding(GO:0016936) |
| 1.0 | 4.8 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 1.0 | 8.7 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 1.0 | 5.8 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 1.0 | 3.9 | GO:0070404 | NADH binding(GO:0070404) |
| 1.0 | 8.6 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 1.0 | 45.7 | GO:0005254 | chloride channel activity(GO:0005254) |
| 1.0 | 11.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.9 | 12.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.9 | 1.9 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.9 | 7.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.9 | 1.9 | GO:0015403 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) |
| 0.9 | 5.6 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.9 | 5.6 | GO:0008430 | selenium binding(GO:0008430) |
| 0.9 | 6.5 | GO:0030551 | cyclic nucleotide binding(GO:0030551) |
| 0.9 | 2.8 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.9 | 16.6 | GO:0005217 | intracellular ligand-gated ion channel activity(GO:0005217) |
| 0.9 | 10.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.9 | 87.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.9 | 16.4 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.9 | 10.0 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.9 | 78.7 | GO:0005179 | hormone activity(GO:0005179) |
| 0.9 | 1.8 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.9 | 1.8 | GO:0019862 | IgA binding(GO:0019862) |
| 0.9 | 2.7 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.9 | 2.7 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.9 | 8.0 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.9 | 6.2 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.9 | 4.4 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.9 | 3.4 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.9 | 4.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.8 | 4.2 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.8 | 7.6 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.8 | 4.1 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.8 | 5.7 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.8 | 4.9 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.8 | 15.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.8 | 4.8 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.8 | 30.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.8 | 11.0 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.8 | 6.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.8 | 15.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.7 | 8.2 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.7 | 8.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.7 | 14.7 | GO:0004675 | transmembrane receptor protein serine/threonine kinase activity(GO:0004675) |
| 0.7 | 2.9 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.7 | 1.5 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.7 | 4.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.7 | 10.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.7 | 7.3 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.7 | 20.3 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.7 | 5.7 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.7 | 2.9 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.7 | 2.1 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 0.7 | 6.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.7 | 191.7 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.7 | 10.5 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.7 | 4.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.7 | 6.8 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.7 | 15.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.7 | 14.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.7 | 4.0 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.7 | 3.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.7 | 0.7 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.7 | 2.0 | GO:0005011 | macrophage colony-stimulating factor receptor activity(GO:0005011) |
| 0.7 | 3.3 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.6 | 2.6 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.6 | 10.8 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.6 | 1.9 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.6 | 1.9 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.6 | 0.6 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.6 | 3.0 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.6 | 3.6 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.6 | 3.5 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.6 | 2.9 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.6 | 2.9 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.6 | 1.2 | GO:0042165 | neurotransmitter binding(GO:0042165) |
| 0.6 | 2.3 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 0.6 | 5.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.6 | 1.7 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.6 | 2.8 | GO:0015197 | peptide transporter activity(GO:0015197) peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) peptide transmembrane transporter activity(GO:1904680) |
| 0.6 | 6.7 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.6 | 3.9 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.6 | 1.1 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.6 | 1.7 | GO:0016160 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
| 0.6 | 2.8 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.5 | 1.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.5 | 1.6 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.5 | 5.8 | GO:0019864 | IgG binding(GO:0019864) |
| 0.5 | 3.7 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.5 | 5.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.5 | 13.2 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.5 | 71.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.5 | 6.8 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.5 | 5.7 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.5 | 5.7 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.5 | 2.1 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.5 | 19.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.5 | 2.6 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.5 | 8.0 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.5 | 1.5 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.5 | 6.0 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.5 | 7.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.5 | 61.6 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.5 | 6.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.5 | 1.9 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.5 | 1.4 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.5 | 1.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.5 | 1.4 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 0.5 | 1.4 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.5 | 2.3 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.5 | 8.7 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.5 | 3.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.5 | 2.3 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.4 | 2.2 | GO:0052828 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.4 | 11.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.4 | 2.2 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.4 | 10.9 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.4 | 8.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.4 | 3.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.4 | 3.0 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.4 | 8.1 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.4 | 7.5 | GO:1901476 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
| 0.4 | 7.0 | GO:0035586 | purinergic receptor activity(GO:0035586) |
| 0.4 | 4.7 | GO:0019841 | retinol binding(GO:0019841) |
| 0.4 | 0.8 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.4 | 5.9 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.4 | 4.7 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.4 | 16.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.4 | 0.8 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.4 | 1.9 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.4 | 3.0 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.4 | 8.4 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.4 | 5.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.4 | 0.4 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.4 | 3.5 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.3 | 4.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.3 | 17.0 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.3 | 3.4 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.3 | 62.2 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.3 | 1.3 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.3 | 2.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.3 | 7.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.3 | 327.9 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.3 | 11.9 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 0.3 | 4.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.3 | 3.1 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.3 | 0.6 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.3 | 7.0 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.3 | 3.0 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.3 | 1.5 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.3 | 10.6 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.3 | 15.5 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.3 | 0.6 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 0.3 | 0.6 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.3 | 5.6 | GO:0005501 | retinoid binding(GO:0005501) |
| 0.3 | 1.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 1.4 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.3 | 1.3 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.3 | 14.2 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.3 | 2.6 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.3 | 0.5 | GO:0050473 | arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.3 | 1.0 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.3 | 2.0 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.3 | 1.8 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.2 | 4.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.2 | 4.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.2 | 1.0 | GO:0033897 | ribonuclease T2 activity(GO:0033897) |
| 0.2 | 2.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.2 | 2.8 | GO:0016849 | phosphorus-oxygen lyase activity(GO:0016849) |
| 0.2 | 20.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 1.6 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.2 | 2.5 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 2.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 2.5 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.2 | 1.3 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.2 | 41.5 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.2 | 0.6 | GO:0004577 | N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577) |
| 0.2 | 0.8 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.2 | 0.8 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.2 | 1.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.2 | 0.5 | GO:0052794 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.2 | 1.4 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.2 | 0.7 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.2 | 1.9 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 0.7 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.2 | 0.3 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.2 | 4.6 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 1.4 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.2 | 3.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 4.1 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 3.2 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 2.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 0.8 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.1 | 4.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 1.1 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 1.3 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.1 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.1 | 0.7 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 0.9 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.2 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.1 | 1.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.3 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.4 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.1 | 0.7 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.1 | 2.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.2 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.3 | GO:0036122 | BMP binding(GO:0036122) |
| 0.0 | 0.6 | GO:0035064 | methylated histone binding(GO:0035064) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.1 | 257.7 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 5.3 | 5.3 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 4.3 | 328.3 | PID RHOA PATHWAY | RhoA signaling pathway |
| 3.5 | 41.6 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 3.0 | 65.4 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 2.9 | 70.3 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 2.7 | 2.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 2.5 | 17.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 2.4 | 49.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 2.1 | 10.5 | ST GAQ PATHWAY | G alpha q Pathway |
| 2.1 | 14.7 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 2.1 | 14.5 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 2.0 | 292.0 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 2.0 | 39.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 1.9 | 49.4 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 1.9 | 20.7 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 1.9 | 7.5 | ST STAT3 PATHWAY | STAT3 Pathway |
| 1.8 | 179.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 1.8 | 1.8 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 1.7 | 14.9 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 1.6 | 21.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 1.6 | 3.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 1.6 | 23.8 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 1.6 | 17.4 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 1.6 | 20.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 1.5 | 25.4 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 1.5 | 32.4 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 1.5 | 55.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 1.4 | 15.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 1.4 | 5.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 1.4 | 15.5 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.4 | 45.9 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 1.3 | 16.4 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 1.2 | 6.2 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 1.2 | 4.9 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 1.2 | 23.5 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 1.1 | 4.5 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 1.1 | 196.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 1.1 | 6.4 | PID ALK1 PATHWAY | ALK1 signaling events |
| 1.1 | 11.7 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 1.1 | 21.3 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 1.1 | 56.5 | PID ARF6 PATHWAY | Arf6 signaling events |
| 1.1 | 39.4 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 1.0 | 3.1 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 1.0 | 17.8 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 1.0 | 11.5 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 1.0 | 13.2 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 1.0 | 58.6 | PID FGF PATHWAY | FGF signaling pathway |
| 1.0 | 57.6 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 1.0 | 5.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 1.0 | 13.8 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 1.0 | 48.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 1.0 | 38.3 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 1.0 | 42.5 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 1.0 | 34.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 1.0 | 5.7 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.9 | 20.8 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.9 | 19.6 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.9 | 2.8 | ST ADRENERGIC | Adrenergic Pathway |
| 0.9 | 17.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.9 | 18.0 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.9 | 243.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.9 | 25.7 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.9 | 49.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.9 | 6.9 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.8 | 14.4 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.8 | 100.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.8 | 12.2 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.8 | 7.3 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.8 | 49.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.8 | 11.0 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.8 | 6.9 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.7 | 6.7 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.7 | 6.6 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.7 | 6.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.7 | 7.2 | PID EPO PATHWAY | EPO signaling pathway |
| 0.7 | 1.3 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.7 | 14.4 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.6 | 7.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.6 | 1.9 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.6 | 31.1 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.6 | 5.9 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.6 | 5.3 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.6 | 13.3 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.6 | 19.8 | PID ATM PATHWAY | ATM pathway |
| 0.6 | 25.1 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.5 | 8.9 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.5 | 14.6 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.5 | 3.6 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.5 | 9.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.5 | 4.2 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.5 | 17.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.5 | 3.3 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.5 | 24.9 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.4 | 4.0 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.4 | 0.8 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.4 | 10.9 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.4 | 6.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.4 | 11.7 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.4 | 9.1 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.4 | 5.1 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.4 | 4.6 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.3 | 0.7 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.3 | 8.7 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.3 | 13.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.3 | 1.8 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.3 | 2.0 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.3 | 2.6 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.3 | 5.2 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.2 | 0.7 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 1.9 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.2 | 12.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 5.2 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.2 | 1.3 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.1 | 40.6 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.1 | 9.0 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 2.4 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 0.7 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 2.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 1.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 96.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 6.0 | 191.7 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 5.0 | 109.9 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 4.6 | 50.9 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 4.4 | 120.0 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 4.4 | 4.4 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 4.2 | 67.5 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 4.1 | 73.7 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 4.0 | 171.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 3.8 | 56.4 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 3.7 | 84.5 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 3.4 | 78.4 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 3.4 | 40.9 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 3.4 | 182.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 3.2 | 32.3 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 3.2 | 22.3 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 3.1 | 43.6 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 3.1 | 18.4 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 3.0 | 39.2 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 3.0 | 108.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 3.0 | 14.9 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 2.9 | 76.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 2.9 | 29.4 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 2.9 | 60.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 2.7 | 21.9 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 2.7 | 49.0 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 2.6 | 52.4 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 2.6 | 98.4 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 2.6 | 139.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 2.4 | 50.4 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 2.4 | 14.2 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 2.3 | 9.3 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 2.3 | 15.8 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 2.2 | 28.3 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 2.0 | 300.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 2.0 | 36.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 1.9 | 73.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 1.9 | 24.9 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 1.9 | 28.4 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 1.9 | 3.7 | REACTOME SIGNALING BY ILS | Genes involved in Signaling by Interleukins |
| 1.8 | 78.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 1.8 | 41.8 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 1.8 | 23.3 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 1.8 | 36.8 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 1.7 | 67.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 1.7 | 8.3 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 1.7 | 28.2 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 1.6 | 101.7 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 1.6 | 26.2 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 1.6 | 45.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 1.6 | 30.9 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 1.6 | 37.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 1.6 | 40.3 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 1.6 | 11.2 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 1.5 | 7.7 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 1.5 | 29.9 | REACTOME DEFENSINS | Genes involved in Defensins |
| 1.5 | 19.1 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 1.4 | 28.6 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 1.4 | 65.5 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 1.4 | 14.2 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 1.4 | 32.7 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 1.4 | 26.8 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 1.4 | 148.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 1.4 | 32.3 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 1.3 | 17.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 1.3 | 13.5 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 1.3 | 11.9 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 1.3 | 108.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 1.3 | 23.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 1.3 | 22.9 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 1.3 | 8.8 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 1.2 | 36.1 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 1.2 | 56.8 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 1.2 | 19.5 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 1.2 | 80.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 1.2 | 29.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 1.2 | 67.7 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 1.2 | 19.3 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 1.2 | 14.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 1.2 | 10.7 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 1.2 | 10.5 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
| 1.2 | 67.9 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 1.1 | 115.6 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 1.1 | 34.3 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 1.1 | 6.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 1.1 | 6.6 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 1.1 | 6.6 | REACTOME GPCR DOWNSTREAM SIGNALING | Genes involved in GPCR downstream signaling |
| 1.1 | 35.0 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 1.1 | 7.5 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 1.1 | 14.8 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 1.0 | 16.7 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 1.0 | 47.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 1.0 | 165.4 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 1.0 | 8.2 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 1.0 | 13.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.0 | 5.0 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 1.0 | 5.0 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.9 | 20.4 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.9 | 17.5 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.9 | 10.4 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.8 | 12.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.8 | 46.2 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.8 | 12.3 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.8 | 21.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.8 | 4.0 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.8 | 16.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.8 | 0.8 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.8 | 12.3 | REACTOME FGFR LIGAND BINDING AND ACTIVATION | Genes involved in FGFR ligand binding and activation |
| 0.8 | 3.8 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.8 | 11.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.7 | 26.2 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.7 | 3.7 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.7 | 0.7 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.7 | 18.9 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.7 | 15.4 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.7 | 9.0 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.7 | 17.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.7 | 6.8 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.7 | 4.8 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.7 | 4.8 | REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT | Genes involved in Lipid digestion, mobilization, and transport |
| 0.7 | 42.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.7 | 21.4 | REACTOME IL 2 SIGNALING | Genes involved in Interleukin-2 signaling |
| 0.6 | 7.6 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.6 | 15.5 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.6 | 8.2 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.6 | 11.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.5 | 4.9 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.5 | 6.2 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.5 | 15.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.5 | 38.6 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.5 | 4.9 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.5 | 167.4 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.5 | 8.3 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.4 | 10.3 | REACTOME SIGNALING BY FGFR MUTANTS | Genes involved in Signaling by FGFR mutants |
| 0.4 | 4.5 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.4 | 2.4 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.4 | 1.9 | REACTOME ADAPTIVE IMMUNE SYSTEM | Genes involved in Adaptive Immune System |
| 0.4 | 8.0 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.4 | 2.2 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.3 | 6.0 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.3 | 7.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.3 | 3.6 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.3 | 1.7 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.3 | 6.6 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.3 | 8.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 8.1 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 12.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.2 | 2.7 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.2 | 5.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 1.9 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.2 | 0.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 5.3 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.2 | 4.8 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 2.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 10.4 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.2 | 5.4 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 1.5 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.2 | 0.5 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.2 | 4.8 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.1 | 2.1 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 2.7 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.1 | 2.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 0.7 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.5 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.0 | 0.5 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.2 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.3 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |