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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ID4_TCF4_SNAI2

Z-value: 8.59

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Transcription factors associated with ID4_TCF4_SNAI2

Gene Symbol Gene ID Gene Info
ENSG00000172201.12 ID4
ENSG00000196628.20 TCF4
ENSG00000019549.13 SNAI2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SNAI2hg38_v1_chr8_-_48921419_48921437-0.562.1e-19Click!
TCF4hg38_v1_chr18_-_55422306_554223610.414.7e-10Click!
ID4hg38_v1_chr6_+_19837362_198373810.291.7e-05Click!

Activity profile of ID4_TCF4_SNAI2 motif

Sorted Z-values of ID4_TCF4_SNAI2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ID4_TCF4_SNAI2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_143734133 108.82 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr19_+_38264563 94.26 ENST00000301244.12
ENST00000587090.5
ENST00000454580.7
serine peptidase inhibitor, Kunitz type 2
chr19_-_7874361 91.38 ENST00000618550.5
proline rich 36
chr9_+_17579059 81.75 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr19_+_18683656 73.43 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chr5_+_157266079 73.01 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr7_-_22356914 72.78 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr3_-_139044892 72.40 ENST00000413199.1
proline rich 23C
chrX_-_13938378 69.16 ENST00000398361.7
glycoprotein M6B
chr10_+_91220603 65.73 ENST00000336126.6
polycomb group ring finger 5
chr16_-_74774812 65.47 ENST00000219368.8
fatty acid 2-hydroxylase
chr17_-_81131933 65.02 ENST00000417379.6
apoptosis associated tyrosine kinase
chr6_+_150683593 63.33 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chrX_-_13938618 61.57 ENST00000454189.6
glycoprotein M6B
chr1_+_220690354 58.35 ENST00000294889.6
chromosome 1 open reading frame 115
chr8_-_126557691 58.16 ENST00000652209.1
LRAT domain containing 2
chr18_-_77132771 57.62 ENST00000355994.7
ENST00000579129.5
myelin basic protein
chr2_+_238138661 56.23 ENST00000409223.2
kelch like family member 30
chr11_-_22829793 55.43 ENST00000354193.5
small VCP interacting protein
chr3_+_167735704 53.98 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr2_+_17540670 53.65 ENST00000451533.5
ENST00000295156.9
visinin like 1
chr16_+_4734457 53.24 ENST00000590191.1
chromosome 16 open reading frame 71
chr7_-_44325421 53.00 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr7_-_44325490 52.91 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr4_+_127965429 51.59 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr8_-_27605271 51.18 ENST00000522098.1
clusterin
chr12_+_32399517 50.61 ENST00000534526.7
FYVE, RhoGEF and PH domain containing 4
chr8_-_109644766 48.46 ENST00000533065.5
ENST00000276646.14
syntabulin
chr1_+_59814939 47.88 ENST00000371208.5
hook microtubule tethering protein 1
chr20_+_45406560 47.55 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr17_-_80476597 47.28 ENST00000306773.5
neuronal pentraxin 1
chr1_+_2050387 46.96 ENST00000378567.8
protein kinase C zeta
chr14_+_75279637 46.74 ENST00000555686.1
ENST00000555672.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr19_-_56671746 46.34 ENST00000537055.4
ENST00000601659.1
zinc finger protein 835
chr2_-_135530561 46.02 ENST00000536680.5
ENST00000401392.5
zinc finger RANBP2-type containing 3
chr1_+_2073986 45.34 ENST00000461106.6
protein kinase C zeta
chr2_-_223837553 44.78 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr16_+_58463663 43.31 ENST00000258187.9
NDRG family member 4
chr1_-_183418364 43.03 ENST00000287713.7
nicotinamide nucleotide adenylyltransferase 2
chr9_+_136979042 42.71 ENST00000446677.2
prostaglandin D2 synthase
chr16_+_6483379 41.19 ENST00000552089.5
RNA binding fox-1 homolog 1
chr17_-_58527980 40.98 ENST00000583114.5
septin 4
chr15_+_74541200 40.93 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr3_-_47578832 40.91 ENST00000264723.9
ENST00000610462.1
chondroitin sulfate proteoglycan 5
chr14_+_75280078 40.61 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr14_-_21025000 40.49 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr2_-_88857582 40.02 ENST00000390237.2
immunoglobulin kappa constant
chr4_+_155667096 39.82 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr8_+_141417902 39.72 ENST00000681443.1
protein tyrosine phosphatase 4A3
chr14_+_105314711 39.46 ENST00000447393.6
ENST00000547217.5
phosphofurin acidic cluster sorting protein 2
chr16_+_4734519 39.36 ENST00000299320.10
chromosome 16 open reading frame 71
chr6_+_11537738 39.33 ENST00000379426.2
transmembrane protein 170B
chr1_-_40665654 39.18 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chr22_+_41469104 39.00 ENST00000677554.1
ENST00000466237.2
ENST00000216254.9
ENST00000678788.1
ENST00000676792.1
ENST00000677153.1
ENST00000396512.3
ENST00000678269.1
ENST00000677532.1
aconitase 2
chr19_+_57240610 38.99 ENST00000414468.3
zinc finger protein 805
chr16_+_6483728 38.74 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr10_+_80408503 38.61 ENST00000606162.6
peroxiredoxin like 2A
chr11_+_123590939 38.49 ENST00000646146.1
GRAM domain containing 1B
chr22_-_18936142 38.37 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr6_-_119078642 38.06 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr16_+_68737284 37.58 ENST00000261769.10
ENST00000422392.6
cadherin 1
chr8_-_17413345 37.51 ENST00000180173.10
myotubularin related protein 7
chr19_-_3028356 37.47 ENST00000586422.5
TLE family member 2, transcriptional corepressor
chr13_+_41457543 37.28 ENST00000379359.4
regulator of cell cycle
chr15_+_44288701 37.24 ENST00000299957.11
ENST00000559222.5
ENST00000650436.1
golgi membrane protein 2
chr2_-_24360445 36.74 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
intersectin 2
chr4_+_155666963 35.79 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr7_-_44325653 35.44 ENST00000440254.6
calcium/calmodulin dependent protein kinase II beta
chr16_+_6483813 35.38 ENST00000675653.1
RNA binding fox-1 homolog 1
chr4_+_155667198 35.33 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr11_-_5227063 34.79 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr9_+_6757633 34.70 ENST00000401787.7
ENST00000381306.7
lysine demethylase 4C
chr1_-_161021096 34.39 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr17_-_42050587 34.14 ENST00000587304.3
chromosome 17 open reading frame 113
chr9_+_137788758 33.99 ENST00000493484.5
euchromatic histone lysine methyltransferase 1
chr6_-_136550407 33.92 ENST00000354570.8
microtubule associated protein 7
chr7_+_100101657 33.90 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chr7_-_98252117 33.78 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr17_+_42458844 33.45 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATPase H+ transporting V0 subunit a1
chr14_+_71932397 33.43 ENST00000553525.6
ENST00000555571.5
regulator of G protein signaling 6
chr4_+_154743993 33.33 ENST00000336356.4
lecithin retinol acyltransferase
chr15_+_90234189 33.19 ENST00000559204.6
ENST00000329600.8
ENST00000558291.2
GDP-D-glucose phosphorylase 1
chr3_+_141402322 33.14 ENST00000510338.5
ENST00000504673.5
zinc finger and BTB domain containing 38
chr2_+_99141696 33.12 ENST00000650052.2
ENST00000409684.2
chromosome 2 open reading frame 15
chr1_-_3857369 32.99 ENST00000674558.1
centrosomal protein 104
chr9_-_94639473 32.97 ENST00000375326.9
fructose-bisphosphatase 1
chr3_+_10026409 32.91 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr11_-_65117639 32.77 ENST00000528598.1
ENST00000310597.6
zinc finger HIT-type containing 2
chr17_-_81166160 32.72 ENST00000326724.9
apoptosis associated tyrosine kinase
chr7_-_727242 32.55 ENST00000537384.6
ENST00000417852.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr8_+_1973668 32.46 ENST00000320248.4
kelch repeat and BTB domain containing 11
chr15_-_34337462 32.43 ENST00000676379.1
solute carrier family 12 member 6
chrX_+_103215072 32.41 ENST00000372695.6
ENST00000372691.3
brain expressed X-linked 4
chr3_-_183825513 32.41 ENST00000318631.8
ENST00000431348.1
MAP6 domain containing 1
chr16_-_30021288 32.19 ENST00000574405.5
double C2 domain alpha
chr1_+_24556087 32.18 ENST00000374392.3
non-compact myelin associated protein
chr6_-_158999748 32.18 ENST00000449822.5
radial spoke head 3
chr1_+_220786853 32.03 ENST00000366910.10
mitochondrial amidoxime reducing component 1
chr1_-_11805977 31.94 ENST00000376486.3
methylenetetrahydrofolate reductase
chr9_+_137788781 31.93 ENST00000482340.5
euchromatic histone lysine methyltransferase 1
chr4_-_5888400 31.55 ENST00000397890.6
collapsin response mediator protein 1
chr6_-_136550819 31.44 ENST00000616617.4
ENST00000618822.4
microtubule associated protein 7
chr15_+_44288757 31.01 ENST00000345795.6
golgi membrane protein 2
chr20_+_45406162 30.98 ENST00000357275.6
ENST00000372720.7
dysbindin domain containing 2
chr4_+_155666827 30.94 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr8_+_79611727 30.90 ENST00000518491.1
stathmin 2
chr7_+_140404034 30.87 ENST00000537763.6
RAB19, member RAS oncogene family
chr5_+_65722190 30.86 ENST00000380985.10
ENST00000502464.5
neurolysin
chr1_+_95117324 30.76 ENST00000370203.9
ENST00000456991.5
TLC domain containing 4
chr3_+_35639589 30.70 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr19_-_50823778 30.52 ENST00000301420.3
kallikrein 1
chr11_+_1390273 30.47 ENST00000526678.5
BR serine/threonine kinase 2
chr12_+_6310669 30.31 ENST00000684764.1
pleckstrin homology and RhoGEF domain containing G6
chr4_+_127965394 30.22 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr9_+_126914760 30.21 ENST00000424082.6
ENST00000259351.10
ENST00000394022.7
ENST00000394011.7
ENST00000319107.8
Ral GEF with PH domain and SH3 binding motif 1
chr15_+_75347610 30.08 ENST00000564784.5
ENST00000569035.5
nei like DNA glycosylase 1
chr7_-_37448845 30.02 ENST00000310758.9
engulfment and cell motility 1
chr15_+_75347030 29.97 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr14_+_94612383 29.96 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr16_+_84145256 29.90 ENST00000378553.10
dynein axonemal assembly factor 1
chr5_-_1294989 29.85 ENST00000334602.10
ENST00000310581.10
telomerase reverse transcriptase
chr16_+_56589521 29.82 ENST00000200691.5
ENST00000570176.1
metallothionein 3
chr1_+_117606040 29.72 ENST00000369448.4
terminal nucleotidyltransferase 5C
chr2_-_2326378 29.66 ENST00000647618.1
myelin transcription factor 1 like
chr15_+_50182188 29.46 ENST00000267842.10
solute carrier family 27 member 2
chr19_+_5904856 29.42 ENST00000339485.4
vimentin type intermediate filament associated coiled-coil protein
chr20_+_46029206 29.15 ENST00000243964.7
solute carrier family 12 member 5
chr19_-_40226682 29.15 ENST00000430325.7
ENST00000599263.6
cyclin P
chr8_-_17413301 29.09 ENST00000521857.5
myotubularin related protein 7
chr7_+_100101556 29.01 ENST00000438383.5
ENST00000429084.5
ENST00000439416.5
adaptor related protein complex 4 subunit mu 1
chr11_-_123654581 28.99 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr20_+_46029165 28.99 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chr3_-_48556785 28.74 ENST00000232375.8
ENST00000383734.6
ENST00000416568.5
ENST00000412035.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr3_-_49120785 28.63 ENST00000417901.5
ENST00000306026.5
ENST00000434032.6
ubiquitin specific peptidase 19
chr20_+_44966478 28.62 ENST00000499879.6
ENST00000372806.8
ENST00000372801.5
serine/threonine kinase 4
chr1_+_8945858 28.52 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr4_-_46909235 28.51 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr14_-_21022095 28.43 ENST00000635386.1
NDRG family member 2
chr17_-_35089212 28.39 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr2_-_216694794 28.32 ENST00000449583.1
insulin like growth factor binding protein 5
chr17_+_18260558 28.27 ENST00000578174.5
ENST00000395704.8
ENST00000395703.8
ENST00000578621.5
ENST00000579341.5
ENST00000323019.9
mitochondrial elongation factor 2
chr19_-_17075038 28.26 ENST00000593360.1
HAUS augmin like complex subunit 8
chr5_-_135578983 28.17 ENST00000512158.6
C-X-C motif chemokine ligand 14
chr4_-_46909206 28.17 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr11_-_111911759 28.14 ENST00000650687.2
crystallin alpha B
chr19_+_2096960 28.03 ENST00000588003.5
IZUMO family member 4
chr18_+_74148508 27.99 ENST00000580087.5
ENST00000169551.11
translocase of inner mitochondrial membrane 21
chr7_+_148339452 27.98 ENST00000463592.3
contactin associated protein 2
chr2_+_172735912 27.81 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chr4_+_113049479 27.71 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ankyrin 2
chr2_+_241702027 27.67 ENST00000313552.11
ENST00000406941.5
inhibitor of growth family member 5
chr1_-_156248038 27.63 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr11_-_123654939 27.45 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr2_+_232662733 27.44 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr14_-_21023954 27.37 ENST00000554094.5
NDRG family member 2
chr19_+_17527250 27.13 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
niban apoptosis regulator 3
chr12_+_130337872 27.13 ENST00000245255.7
piwi like RNA-mediated gene silencing 1
chr7_+_103075123 27.05 ENST00000323716.8
ENST00000434153.1
armadillo repeat containing 10
chr7_-_51316754 26.95 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
cordon-bleu WH2 repeat protein
chr18_-_59273379 26.93 ENST00000256852.7
retina and anterior neural fold homeobox
chr12_+_108515262 26.88 ENST00000552695.6
ENST00000552758.1
ENST00000361549.2
FIC domain protein adenylyltransferase
chr1_-_223364059 26.88 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr18_-_6414885 26.87 ENST00000317931.12
ENST00000400104.7
L3MBTL histone methyl-lysine binding protein 4
chr7_+_45574358 26.85 ENST00000297323.12
adenylate cyclase 1
chr21_+_39867387 26.82 ENST00000328619.10
Purkinje cell protein 4
chr4_-_176002332 26.70 ENST00000280187.11
ENST00000512509.5
glycoprotein M6A
chr22_-_35622521 26.46 ENST00000419229.1
ENST00000406324.5
myoglobin
chr4_+_139454070 26.43 ENST00000305626.6
RAB33B, member RAS oncogene family
chr15_-_82647503 26.43 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr15_+_32641665 26.29 ENST00000300175.8
ENST00000413748.6
ENST00000494364.5
ENST00000497208.5
secretogranin V
chr14_+_75069632 26.28 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr18_+_24113341 26.27 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr4_-_36244438 26.23 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_176188658 26.23 ENST00000331462.6
homeobox D1
chr16_+_1989949 26.21 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr12_+_50104000 26.14 ENST00000548814.1
ENST00000301149.8
glycerol-3-phosphate dehydrogenase 1
chr19_+_41003946 26.11 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr9_+_112486819 26.11 ENST00000337530.11
KIAA1958
chr1_-_156248013 26.10 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr16_-_2340703 26.10 ENST00000301732.10
ENST00000382381.7
ATP binding cassette subfamily A member 3
chr10_-_60733467 26.06 ENST00000373827.6
ankyrin 3
chr7_+_100101632 26.01 ENST00000359593.9
adaptor related protein complex 4 subunit mu 1
chr3_-_49120887 25.97 ENST00000453664.5
ENST00000398888.6
ubiquitin specific peptidase 19
chr19_+_8413270 25.90 ENST00000381035.8
ENST00000595142.5
ENST00000601724.5
ENST00000601283.5
ENST00000215555.7
ENST00000595213.1
membrane associated ring-CH-type finger 2
chr15_+_23565705 25.85 ENST00000568252.1
ENST00000649065.1
makorin ring finger protein 3
chr14_-_21025490 25.73 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr1_+_69567906 25.68 ENST00000651989.2
leucine rich repeat containing 7
chr11_+_73647549 25.65 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr14_+_64540734 25.63 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr22_+_30694851 25.55 ENST00000332585.11
oxysterol binding protein 2
chr6_-_6007511 25.52 ENST00000616243.1
neuritin 1
chr10_-_21174187 25.48 ENST00000417816.2
nebulette
chr16_-_4937064 25.32 ENST00000590782.6
ENST00000345988.7
periplakin
chr5_-_160685379 25.31 ENST00000642502.1
ATPase phospholipid transporting 10B (putative)
chr11_+_68008542 25.23 ENST00000614849.4
aldehyde dehydrogenase 3 family member B1
chr17_-_7262343 25.20 ENST00000571881.2
ENST00000360325.11
claudin 7
chr4_+_113049616 25.13 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr11_+_65111845 24.97 ENST00000526809.5
ENST00000524986.5
ENST00000534371.5
ENST00000279263.14
ENST00000525385.5
ENST00000345348.9
ENST00000531321.5
ENST00000529414.5
ENST00000526085.5
ENST00000530750.5
transmembrane 7 superfamily member 2
chr1_+_35557435 24.88 ENST00000373253.7
neurochondrin
chr5_+_134905100 24.80 ENST00000512783.5
ENST00000254908.11
pterin-4 alpha-carbinolamine dehydratase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
40.7 122.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
24.5 73.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
19.0 19.0 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861)
18.5 92.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
17.1 51.3 GO:0036292 DNA rewinding(GO:0036292)
16.3 49.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
16.0 48.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
15.6 46.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
15.0 75.0 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
14.8 73.8 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
14.3 57.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
13.9 41.7 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
13.8 41.4 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
13.8 55.1 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
13.5 53.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
13.4 40.1 GO:0030185 nitric oxide transport(GO:0030185)
13.0 39.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
12.7 50.9 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
12.4 74.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
12.3 49.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
12.2 48.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
12.1 121.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
12.1 12.1 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
12.0 204.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
11.9 83.0 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
11.7 35.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
11.6 34.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
11.5 57.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
11.4 68.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
11.1 133.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
10.8 43.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
10.7 74.8 GO:0034587 piRNA metabolic process(GO:0034587)
10.5 52.5 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
10.5 94.5 GO:0001661 conditioned taste aversion(GO:0001661)
10.3 30.9 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
10.2 204.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
10.0 60.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
10.0 40.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
9.9 29.8 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
9.7 29.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
9.5 28.4 GO:0010587 miRNA catabolic process(GO:0010587)
9.4 28.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
9.4 28.2 GO:0036048 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
9.3 9.3 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
9.2 36.9 GO:0051866 general adaptation syndrome(GO:0051866)
9.2 36.8 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
9.2 27.6 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
9.2 9.2 GO:0036146 cellular response to mycotoxin(GO:0036146)
9.1 54.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
9.0 54.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
9.0 18.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
9.0 26.9 GO:0001757 somite specification(GO:0001757)
8.8 70.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
8.7 8.7 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
8.7 43.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
8.3 24.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
8.2 32.7 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
8.1 97.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
7.9 31.8 GO:0002159 desmosome assembly(GO:0002159)
7.9 23.7 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
7.8 23.3 GO:0009720 detection of hormone stimulus(GO:0009720)
7.7 38.3 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
7.7 7.7 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
7.6 22.7 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
7.6 37.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
7.5 29.8 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
7.4 51.8 GO:0015705 iodide transport(GO:0015705)
7.3 36.7 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
7.3 29.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
7.3 14.6 GO:0006021 inositol biosynthetic process(GO:0006021)
7.3 14.5 GO:0046689 response to mercury ion(GO:0046689)
7.3 7.3 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
7.2 57.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
7.1 28.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
7.0 28.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
7.0 20.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
7.0 69.6 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
7.0 62.7 GO:0046959 habituation(GO:0046959)
7.0 20.9 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
6.9 13.8 GO:0046878 positive regulation of saliva secretion(GO:0046878)
6.8 47.7 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
6.7 106.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
6.5 39.1 GO:0038016 insulin receptor internalization(GO:0038016)
6.4 19.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
6.3 6.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of muscle adaptation(GO:0014744) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
6.3 18.8 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
6.2 6.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
6.2 12.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
6.2 18.5 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
6.1 18.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
6.1 24.4 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
6.1 18.3 GO:0000103 sulfate assimilation(GO:0000103)
6.1 6.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
6.0 24.1 GO:0009822 alkaloid catabolic process(GO:0009822)
6.0 18.1 GO:0061760 antifungal innate immune response(GO:0061760)
6.0 6.0 GO:0005985 sucrose metabolic process(GO:0005985)
6.0 17.9 GO:0019075 virus maturation(GO:0019075)
5.9 17.6 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
5.8 29.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
5.8 28.9 GO:0006127 glycerophosphate shuttle(GO:0006127)
5.8 17.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
5.8 17.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
5.8 23.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
5.7 11.5 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
5.7 17.2 GO:0071810 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
5.7 5.7 GO:0001796 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
5.7 39.7 GO:0070560 protein secretion by platelet(GO:0070560)
5.6 33.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
5.6 61.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
5.6 28.0 GO:0071109 superior temporal gyrus development(GO:0071109)
5.6 11.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
5.6 11.1 GO:1903413 cellular response to bile acid(GO:1903413)
5.6 44.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
5.6 5.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
5.5 22.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
5.5 94.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
5.5 60.0 GO:0032074 negative regulation of nuclease activity(GO:0032074)
5.4 70.5 GO:0006776 vitamin A metabolic process(GO:0006776)
5.4 16.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
5.4 21.6 GO:0050916 sensory perception of sweet taste(GO:0050916)
5.4 10.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
5.3 37.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
5.3 26.3 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
5.2 68.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
5.2 20.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
5.2 67.8 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
5.1 20.6 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
5.1 10.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
5.1 30.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
5.1 5.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
5.1 10.1 GO:1990641 response to iron ion starvation(GO:1990641)
5.0 20.0 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
5.0 10.0 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
4.9 29.6 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
4.9 24.5 GO:0038161 prolactin signaling pathway(GO:0038161)
4.8 19.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
4.8 23.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
4.8 28.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
4.8 47.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
4.7 23.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
4.7 23.7 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
4.7 18.9 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
4.7 183.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
4.7 9.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
4.7 18.7 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
4.6 4.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
4.6 18.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
4.6 27.4 GO:0014827 intestine smooth muscle contraction(GO:0014827)
4.6 4.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
4.5 31.5 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
4.5 13.5 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
4.5 22.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
4.5 31.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
4.4 22.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
4.4 101.2 GO:0006895 Golgi to endosome transport(GO:0006895)
4.4 8.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
4.4 8.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
4.3 60.8 GO:0006751 glutathione catabolic process(GO:0006751)
4.3 13.0 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
4.3 12.9 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
4.3 42.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
4.3 8.5 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
4.2 17.0 GO:1904640 response to methionine(GO:1904640)
4.2 12.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
4.2 16.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
4.2 8.4 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
4.2 21.1 GO:0016240 autophagosome docking(GO:0016240)
4.2 12.6 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
4.2 21.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
4.2 8.4 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
4.2 8.4 GO:0060032 notochord regression(GO:0060032)
4.2 16.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
4.1 4.1 GO:0061526 acetylcholine secretion(GO:0061526)
4.1 12.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
4.1 24.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
4.1 12.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
4.1 41.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
4.1 8.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
4.1 8.2 GO:0071315 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
4.1 4.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
4.1 16.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
4.1 8.2 GO:0007538 primary sex determination(GO:0007538)
4.1 12.2 GO:2000851 positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
4.1 61.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
4.1 12.2 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
4.0 16.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
4.0 20.1 GO:0014850 response to muscle activity(GO:0014850)
4.0 20.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.0 12.0 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
4.0 12.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
4.0 27.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
4.0 15.9 GO:0014807 regulation of somitogenesis(GO:0014807)
4.0 43.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
4.0 31.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
4.0 15.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.0 4.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
3.9 27.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
3.9 63.0 GO:0071285 cellular response to lithium ion(GO:0071285)
3.9 27.6 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
3.9 35.4 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
3.9 3.9 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
3.9 15.7 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
3.9 15.6 GO:0046968 peptide antigen transport(GO:0046968)
3.9 19.5 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
3.9 50.5 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.9 19.4 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
3.9 15.5 GO:0002399 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
3.9 11.6 GO:0071529 cementum mineralization(GO:0071529)
3.9 3.9 GO:0048341 paraxial mesoderm formation(GO:0048341)
3.8 15.3 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
3.8 7.7 GO:0052314 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
3.8 7.6 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
3.8 22.8 GO:1990034 calcium ion export from cell(GO:1990034)
3.8 11.4 GO:0007525 somatic muscle development(GO:0007525)
3.8 26.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
3.8 11.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
3.7 18.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
3.7 22.5 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
3.7 11.2 GO:0010266 response to vitamin B1(GO:0010266)
3.7 3.7 GO:0002317 plasma cell differentiation(GO:0002317)
3.7 7.5 GO:0071288 cellular response to mercury ion(GO:0071288)
3.7 3.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
3.7 14.9 GO:0072011 glomerular endothelium development(GO:0072011)
3.7 14.9 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
3.7 29.7 GO:0032455 nerve growth factor processing(GO:0032455)
3.7 48.0 GO:0006600 creatine metabolic process(GO:0006600)
3.7 3.7 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
3.7 47.7 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
3.7 14.6 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
3.6 58.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
3.6 47.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
3.6 54.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
3.6 21.7 GO:0072592 oxygen metabolic process(GO:0072592)
3.6 54.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
3.6 14.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
3.6 14.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.6 53.7 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
3.6 21.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
3.6 7.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
3.6 3.6 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
3.5 7.1 GO:0043217 myelin maintenance(GO:0043217)
3.5 10.6 GO:0061218 negative regulation of mesonephros development(GO:0061218)
3.5 14.1 GO:0006531 aspartate metabolic process(GO:0006531)
3.5 31.5 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
3.5 10.4 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
3.5 3.5 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
3.5 10.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
3.5 76.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
3.5 13.8 GO:1990834 response to odorant(GO:1990834)
3.4 17.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
3.4 34.4 GO:1902669 positive regulation of axon guidance(GO:1902669)
3.4 106.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
3.4 17.1 GO:0006041 glucosamine metabolic process(GO:0006041)
3.4 44.3 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
3.4 13.6 GO:0003095 pressure natriuresis(GO:0003095)
3.4 10.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
3.3 10.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
3.3 26.7 GO:0007256 activation of JNKK activity(GO:0007256)
3.3 16.5 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
3.3 26.4 GO:0006498 N-terminal protein lipidation(GO:0006498)
3.3 19.8 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
3.3 3.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
3.3 6.5 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
3.3 19.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
3.2 51.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
3.2 16.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
3.2 3.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
3.2 6.4 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
3.2 22.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
3.2 16.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
3.2 57.7 GO:0015671 oxygen transport(GO:0015671)
3.2 3.2 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
3.2 25.6 GO:0070995 NADPH oxidation(GO:0070995)
3.2 12.8 GO:0019086 late viral transcription(GO:0019086)
3.2 19.2 GO:0048241 epinephrine transport(GO:0048241)
3.2 3.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.2 6.4 GO:0010046 response to mycotoxin(GO:0010046)
3.2 9.5 GO:0070634 transepithelial ammonium transport(GO:0070634)
3.2 28.4 GO:0015693 magnesium ion transport(GO:0015693)
3.2 6.3 GO:0090182 regulation of secretion of lysosomal enzymes(GO:0090182)
3.1 18.9 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
3.1 6.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
3.1 9.4 GO:1903028 positive regulation of opsonization(GO:1903028)
3.1 18.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
3.1 6.3 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
3.1 9.4 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
3.1 15.6 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
3.1 12.5 GO:0071287 cellular response to manganese ion(GO:0071287)
3.1 15.6 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
3.1 15.6 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
3.1 12.4 GO:0099558 maintenance of synapse structure(GO:0099558)
3.1 12.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
3.1 21.6 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
3.1 37.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
3.1 24.6 GO:0009155 purine deoxyribonucleotide catabolic process(GO:0009155)
3.1 30.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
3.1 9.2 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
3.1 45.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
3.1 24.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
3.1 15.3 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
3.1 12.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
3.0 6.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
3.0 57.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
3.0 9.0 GO:0009386 translational attenuation(GO:0009386)
3.0 18.0 GO:1901159 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
3.0 3.0 GO:1901858 regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA replication(GO:0090298) regulation of mitochondrial DNA metabolic process(GO:1901858) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
3.0 8.9 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
3.0 11.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
3.0 8.9 GO:0002933 lipid hydroxylation(GO:0002933)
2.9 2.9 GO:0030320 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
2.9 29.1 GO:1903358 regulation of Golgi organization(GO:1903358)
2.9 17.5 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
2.9 8.6 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
2.9 5.7 GO:0018879 biphenyl metabolic process(GO:0018879)
2.9 136.9 GO:0015701 bicarbonate transport(GO:0015701)
2.8 8.5 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
2.8 17.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
2.8 65.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
2.8 19.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
2.8 189.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
2.8 22.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
2.8 22.6 GO:0021794 thalamus development(GO:0021794)
2.8 5.7 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
2.8 14.1 GO:0015740 C4-dicarboxylate transport(GO:0015740)
2.8 8.4 GO:0021558 trochlear nerve development(GO:0021558)
2.8 2.8 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
2.8 13.9 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.8 22.3 GO:0061709 reticulophagy(GO:0061709)
2.8 13.9 GO:0043587 tongue morphogenesis(GO:0043587)
2.8 5.5 GO:0021891 olfactory bulb interneuron development(GO:0021891)
2.8 2.8 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
2.8 11.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
2.8 11.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.8 24.9 GO:0010226 response to lithium ion(GO:0010226)
2.8 5.5 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
2.7 5.5 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
2.7 11.0 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.7 10.9 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.7 16.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
2.7 8.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
2.7 5.4 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
2.7 18.9 GO:0035095 behavioral response to nicotine(GO:0035095)
2.7 10.8 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
2.7 8.1 GO:0071896 protein localization to adherens junction(GO:0071896)
2.7 16.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
2.7 32.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
2.7 10.6 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
2.6 15.9 GO:0046092 deoxycytidine metabolic process(GO:0046092)
2.6 7.9 GO:0031643 positive regulation of myelination(GO:0031643)
2.6 13.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.6 52.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
2.6 7.8 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
2.6 15.6 GO:0045759 negative regulation of action potential(GO:0045759)
2.6 20.8 GO:0003197 endocardial cushion development(GO:0003197)
2.6 7.7 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
2.6 2.6 GO:0032252 secretory granule localization(GO:0032252)
2.6 10.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
2.6 5.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
2.6 53.6 GO:0021854 hypothalamus development(GO:0021854)
2.5 50.9 GO:0006590 thyroid hormone generation(GO:0006590)
2.5 17.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
2.5 7.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.5 2.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.5 10.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
2.5 20.1 GO:0097186 amelogenesis(GO:0097186)
2.5 45.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
2.5 7.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
2.5 42.5 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
2.5 7.5 GO:1902414 protein localization to cell junction(GO:1902414)
2.5 67.4 GO:0071420 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
2.5 7.5 GO:0002384 hepatic immune response(GO:0002384)
2.5 7.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.5 29.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
2.5 19.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
2.5 9.9 GO:0035900 response to isolation stress(GO:0035900)
2.5 7.4 GO:0006683 galactosylceramide catabolic process(GO:0006683)
2.5 49.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
2.5 19.6 GO:0042426 choline catabolic process(GO:0042426)
2.4 7.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
2.4 4.9 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
2.4 4.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
2.4 4.8 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
2.4 7.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
2.4 12.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
2.4 7.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
2.4 9.6 GO:2000845 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
2.4 19.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.4 7.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
2.4 7.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
2.4 23.9 GO:0048266 behavioral response to pain(GO:0048266)
2.4 23.9 GO:0046185 aldehyde catabolic process(GO:0046185)
2.4 4.8 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
2.4 7.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
2.4 4.8 GO:0032494 response to peptidoglycan(GO:0032494)
2.4 68.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
2.4 4.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
2.3 32.9 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
2.3 4.7 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
2.3 9.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
2.3 9.4 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
2.3 30.2 GO:0060394 negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
2.3 16.2 GO:0036159 inner dynein arm assembly(GO:0036159)
2.3 6.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
2.3 11.4 GO:0019732 antifungal humoral response(GO:0019732)
2.3 111.2 GO:0018149 peptide cross-linking(GO:0018149)
2.3 6.8 GO:1903892 regulation of ATF6-mediated unfolded protein response(GO:1903891) negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
2.2 22.4 GO:1990504 dense core granule exocytosis(GO:1990504)
2.2 6.7 GO:0051684 maintenance of Golgi location(GO:0051684)
2.2 26.7 GO:0030322 stabilization of membrane potential(GO:0030322)
2.2 17.8 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.2 6.6 GO:0038001 paracrine signaling(GO:0038001)
2.2 13.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
2.2 53.1 GO:0051197 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
2.2 6.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
2.2 4.4 GO:0035973 aggrephagy(GO:0035973)
2.2 19.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
2.2 6.6 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.2 37.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
2.2 21.8 GO:0036065 fucosylation(GO:0036065)
2.2 17.4 GO:0015747 urate transport(GO:0015747)
2.2 6.5 GO:0071481 cellular response to X-ray(GO:0071481)
2.2 13.0 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
2.2 6.5 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
2.1 77.4 GO:0045022 early endosome to late endosome transport(GO:0045022)
2.1 42.9 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
2.1 4.2 GO:0031268 pseudopodium organization(GO:0031268)
2.1 8.4 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
2.1 4.2 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
2.1 18.9 GO:0070633 transepithelial transport(GO:0070633)
2.1 14.7 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
2.1 39.9 GO:0001829 trophectodermal cell differentiation(GO:0001829)
2.1 10.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
2.1 20.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.1 6.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
2.1 12.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
2.1 8.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
2.1 6.2 GO:0010958 response to herbicide(GO:0009635) regulation of amino acid import(GO:0010958)
2.1 24.8 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
2.1 6.2 GO:0060283 negative regulation of oocyte development(GO:0060283)
2.1 18.5 GO:0015886 heme transport(GO:0015886)
2.1 61.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
2.1 6.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
2.1 22.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
2.0 71.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
2.0 4.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
2.0 6.1 GO:0072709 cellular response to sorbitol(GO:0072709)
2.0 18.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
2.0 14.2 GO:0031642 negative regulation of myelination(GO:0031642)
2.0 10.1 GO:0033227 dsRNA transport(GO:0033227)
2.0 8.1 GO:0044026 DNA hypermethylation(GO:0044026)
2.0 34.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
2.0 6.0 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
2.0 10.0 GO:0070673 response to interleukin-18(GO:0070673)
2.0 5.9 GO:0018377 protein myristoylation(GO:0018377)
2.0 4.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
2.0 5.9 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
2.0 5.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
2.0 3.9 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
2.0 13.8 GO:0051026 chiasma assembly(GO:0051026)
2.0 3.9 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
2.0 7.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.9 5.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.9 52.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.9 7.8 GO:1900452 regulation of long term synaptic depression(GO:1900452)
1.9 7.7 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
1.9 9.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.9 1.9 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
1.9 28.6 GO:0008089 anterograde axonal transport(GO:0008089)
1.9 36.2 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
1.9 11.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.9 20.9 GO:0060004 reflex(GO:0060004)
1.9 1.9 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
1.9 151.4 GO:1902476 chloride transmembrane transport(GO:1902476)
1.9 34.0 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
1.9 64.1 GO:0001895 retina homeostasis(GO:0001895)
1.9 50.7 GO:0008053 mitochondrial fusion(GO:0008053)
1.9 30.0 GO:0038065 collagen-activated signaling pathway(GO:0038065)
1.9 5.6 GO:1904383 response to sodium phosphate(GO:1904383)
1.9 20.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.9 7.5 GO:0072299 negative regulation of glomerular mesangial cell proliferation(GO:0072125) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194)
1.9 41.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
1.9 9.3 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
1.9 1.9 GO:0051801 cytolysis by symbiont of host cells(GO:0001897) cytolysis in other organism involved in symbiotic interaction(GO:0051801)
1.9 1.9 GO:0019376 galactolipid catabolic process(GO:0019376)
1.9 14.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.8 5.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.8 22.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
1.8 9.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
1.8 3.7 GO:2000328 interleukin-23-mediated signaling pathway(GO:0038155) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
1.8 18.4 GO:0060019 radial glial cell differentiation(GO:0060019)
1.8 45.7 GO:0048665 neuron fate specification(GO:0048665)
1.8 9.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.8 9.0 GO:0015840 urea transport(GO:0015840)
1.8 26.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
1.8 14.3 GO:0007506 gonadal mesoderm development(GO:0007506)
1.8 5.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.8 3.6 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
1.8 41.1 GO:0050919 negative chemotaxis(GO:0050919)
1.8 3.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
1.8 7.1 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
1.8 35.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
1.8 3.5 GO:0050957 equilibrioception(GO:0050957)
1.8 22.9 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.8 10.6 GO:1900424 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803) regulation of defense response to bacterium(GO:1900424) positive regulation of defense response to bacterium(GO:1900426)
1.8 3.5 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
1.8 31.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.8 22.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.8 3.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
1.8 1.8 GO:0042938 dipeptide transport(GO:0042938)
1.7 7.0 GO:0008272 sulfate transport(GO:0008272)
1.7 5.2 GO:0099403 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
1.7 14.0 GO:0006013 mannose metabolic process(GO:0006013)
1.7 3.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.7 19.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
1.7 12.1 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
1.7 1.7 GO:0032971 regulation of muscle filament sliding(GO:0032971)
1.7 17.3 GO:0002227 innate immune response in mucosa(GO:0002227)
1.7 8.6 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
1.7 5.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.7 1.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.7 25.6 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
1.7 10.2 GO:0016554 cytidine to uridine editing(GO:0016554)
1.7 13.6 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
1.7 10.2 GO:1903960 negative regulation of anion transmembrane transport(GO:1903960)
1.7 5.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.7 28.5 GO:0046069 cGMP catabolic process(GO:0046069)
1.7 5.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
1.7 11.7 GO:1901563 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
1.7 5.0 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.6 31.3 GO:0072538 T-helper 17 type immune response(GO:0072538)
1.6 4.9 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
1.6 3.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.6 8.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
1.6 11.4 GO:0090527 actin filament reorganization(GO:0090527)
1.6 4.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.6 8.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
1.6 12.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.6 9.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.6 12.8 GO:0010623 programmed cell death involved in cell development(GO:0010623)
1.6 6.4 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
1.6 9.5 GO:0021650 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
1.6 6.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.6 9.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.6 6.3 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
1.6 6.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.6 3.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
1.6 14.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.6 4.7 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.6 6.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
1.6 9.4 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.6 4.7 GO:0048250 mitochondrial iron ion transport(GO:0048250)
1.6 6.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
1.5 4.6 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.5 20.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.5 6.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
1.5 13.7 GO:0033005 positive regulation of mast cell activation(GO:0033005)
1.5 10.6 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
1.5 25.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
1.5 15.0 GO:0001696 gastric acid secretion(GO:0001696)
1.5 8.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
1.5 7.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.5 22.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
1.5 4.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.5 4.4 GO:0009106 lipoate metabolic process(GO:0009106)
1.5 13.3 GO:0032482 Rab protein signal transduction(GO:0032482)
1.5 32.2 GO:0097503 sialylation(GO:0097503)
1.5 7.3 GO:0006265 DNA topological change(GO:0006265)
1.5 7.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
1.5 5.8 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.5 8.7 GO:0046548 retinal rod cell development(GO:0046548)
1.5 4.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.4 15.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.4 5.8 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
1.4 2.9 GO:1902617 response to fluoride(GO:1902617)
1.4 53.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
1.4 12.8 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.4 7.1 GO:0099515 actin filament-based transport(GO:0099515)
1.4 7.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
1.4 4.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.4 9.9 GO:0071313 cellular response to caffeine(GO:0071313)
1.4 4.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
1.4 4.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.4 11.3 GO:0006477 protein sulfation(GO:0006477)
1.4 11.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
1.4 22.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.4 4.2 GO:0030035 microspike assembly(GO:0030035)
1.4 69.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
1.4 9.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.4 12.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
1.4 16.6 GO:0006824 cobalt ion transport(GO:0006824)
1.4 22.0 GO:0019731 antibacterial humoral response(GO:0019731)
1.4 9.6 GO:0061370 testosterone biosynthetic process(GO:0061370)
1.4 4.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.4 5.4 GO:0010954 positive regulation of protein processing(GO:0010954)
1.4 6.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.3 6.7 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
1.3 8.1 GO:0035617 stress granule disassembly(GO:0035617)
1.3 2.7 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
1.3 4.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.3 8.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
1.3 12.1 GO:0006670 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
1.3 1.3 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
1.3 2.7 GO:0042940 D-amino acid transport(GO:0042940)
1.3 4.0 GO:0060155 platelet dense granule organization(GO:0060155)
1.3 4.0 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.3 17.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
1.3 37.2 GO:0006706 steroid catabolic process(GO:0006706)
1.3 4.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.3 1.3 GO:0033504 floor plate development(GO:0033504)
1.3 9.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.3 2.6 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
1.3 1.3 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
1.3 7.9 GO:0006543 glutamine catabolic process(GO:0006543)
1.3 5.2 GO:0018095 protein polyglutamylation(GO:0018095)
1.3 152.7 GO:0007608 sensory perception of smell(GO:0007608)
1.3 7.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
1.3 5.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.3 14.2 GO:0097107 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.3 5.1 GO:1904424 regulation of GTP binding(GO:1904424)
1.3 11.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.3 21.8 GO:0048268 clathrin coat assembly(GO:0048268)
1.3 2.6 GO:0034378 chylomicron assembly(GO:0034378)
1.3 26.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.3 5.1 GO:0008343 adult feeding behavior(GO:0008343)
1.3 1.3 GO:0030222 eosinophil differentiation(GO:0030222)
1.2 19.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.2 1.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.2 12.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
1.2 10.0 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
1.2 7.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.2 2.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
1.2 3.7 GO:0060736 prostate gland growth(GO:0060736)
1.2 7.4 GO:0007000 nucleolus organization(GO:0007000)
1.2 5.0 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
1.2 4.9 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
1.2 4.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.2 9.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
1.2 13.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
1.2 21.9 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
1.2 10.9 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
1.2 7.3 GO:0035063 nuclear speck organization(GO:0035063)
1.2 4.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
1.2 55.7 GO:0050853 B cell receptor signaling pathway(GO:0050853)
1.2 6.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
1.2 8.4 GO:0044065 regulation of respiratory system process(GO:0044065)
1.2 4.8 GO:0035627 ceramide transport(GO:0035627)
1.2 6.0 GO:0016139 glycoside catabolic process(GO:0016139)
1.2 2.4 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
1.2 3.6 GO:0035574 histone H4-K20 demethylation(GO:0035574)
1.2 7.2 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
1.2 3.6 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
1.2 135.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
1.2 23.8 GO:0043029 T cell homeostasis(GO:0043029)
1.2 7.1 GO:0042118 endothelial cell activation(GO:0042118)
1.2 1.2 GO:0045686 negative regulation of glial cell differentiation(GO:0045686) negative regulation of oligodendrocyte differentiation(GO:0048715)
1.2 8.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.2 15.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
1.2 14.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
1.2 11.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.2 1.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
1.2 11.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.2 3.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.2 1.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.2 15.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
1.2 5.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.2 8.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
1.1 1.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.1 4.6 GO:0019323 pentose catabolic process(GO:0019323)
1.1 6.8 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
1.1 20.4 GO:0009235 cobalamin metabolic process(GO:0009235)
1.1 38.3 GO:0003009 skeletal muscle contraction(GO:0003009)
1.1 2.2 GO:0023058 adaptation of signaling pathway(GO:0023058)
1.1 3.3 GO:0061635 regulation of protein complex stability(GO:0061635)
1.1 3.3 GO:0002371 dendritic cell cytokine production(GO:0002371)
1.1 4.5 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
1.1 125.3 GO:0006958 complement activation, classical pathway(GO:0006958)
1.1 3.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992) negative regulation of urine volume(GO:0035811)
1.1 2.2 GO:0001554 luteolysis(GO:0001554)
1.1 6.5 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
1.1 2.2 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
1.1 17.2 GO:0035082 axoneme assembly(GO:0035082)
1.1 2.2 GO:0071864 regulation of cell proliferation in bone marrow(GO:0071863) positive regulation of cell proliferation in bone marrow(GO:0071864) regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290)
1.1 6.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
1.1 2.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.1 5.3 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
1.1 7.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
1.1 13.8 GO:0015074 DNA integration(GO:0015074)
1.1 15.9 GO:0006896 Golgi to vacuole transport(GO:0006896)
1.1 3.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
1.1 2.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
1.0 8.4 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
1.0 11.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
1.0 5.2 GO:0033080 immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.0 5.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
1.0 2.1 GO:0016999 antibiotic metabolic process(GO:0016999)
1.0 2.1 GO:0030259 lipid glycosylation(GO:0030259)
1.0 2.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
1.0 7.2 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
1.0 23.7 GO:0070830 bicellular tight junction assembly(GO:0070830)
1.0 3.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
1.0 1.0 GO:1903939 regulation of TORC2 signaling(GO:1903939)
1.0 7.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
1.0 6.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.0 4.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
1.0 4.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
1.0 3.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.0 3.0 GO:0015847 putrescine transport(GO:0015847)
1.0 6.1 GO:0071104 response to interleukin-9(GO:0071104)
1.0 9.1 GO:0006020 inositol metabolic process(GO:0006020)
1.0 8.0 GO:0098535 de novo centriole assembly(GO:0098535)
1.0 3.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.0 4.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
1.0 4.9 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.0 4.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
1.0 4.9 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
1.0 1.9 GO:0042631 cellular response to water deprivation(GO:0042631)
1.0 7.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.0 10.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.0 26.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
1.0 1.9 GO:0043589 skin morphogenesis(GO:0043589)
1.0 19.1 GO:0019433 triglyceride catabolic process(GO:0019433)
1.0 2.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.0 5.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.9 5.7 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.9 10.4 GO:0048485 sympathetic nervous system development(GO:0048485)
0.9 20.8 GO:0046847 filopodium assembly(GO:0046847)
0.9 1.9 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.9 33.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.9 4.7 GO:0001575 globoside metabolic process(GO:0001575)
0.9 1.9 GO:0035962 response to interleukin-13(GO:0035962)
0.9 5.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.9 3.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.9 4.6 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.9 10.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.9 4.6 GO:0001782 B cell homeostasis(GO:0001782)
0.9 10.1 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.9 7.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.9 2.7 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
0.9 9.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.9 3.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.9 0.9 GO:1903006 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.9 5.4 GO:0050832 defense response to fungus(GO:0050832)
0.9 9.1 GO:0000050 urea cycle(GO:0000050)
0.9 5.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.9 4.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.9 3.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.9 10.8 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.9 9.7 GO:0001778 plasma membrane repair(GO:0001778)
0.9 5.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.9 4.4 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.9 6.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.9 2.6 GO:0002024 diet induced thermogenesis(GO:0002024)
0.9 20.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.9 0.9 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.9 2.6 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.8 20.4 GO:0051646 mitochondrion localization(GO:0051646)
0.8 7.6 GO:0048007 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.8 2.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.8 4.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.8 21.7 GO:0097484 dendrite extension(GO:0097484)
0.8 3.3 GO:0044804 nucleophagy(GO:0044804)
0.8 1.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.8 19.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.8 9.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.8 4.1 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.8 10.7 GO:0006449 regulation of translational termination(GO:0006449)
0.8 4.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.8 2.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.8 4.9 GO:0035524 proline transmembrane transport(GO:0035524)
0.8 26.0 GO:0016266 O-glycan processing(GO:0016266)
0.8 2.4 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.8 4.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.8 2.4 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.8 9.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.8 4.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.8 4.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.8 5.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.8 2.3 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.8 4.6 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.8 8.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.8 7.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.8 10.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.8 0.8 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.8 2.3 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.8 1.5 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.8 6.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.8 1.5 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.7 13.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.7 4.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.7 2.2 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.7 2.9 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.7 2.2 GO:0050893 sensory processing(GO:0050893)
0.7 11.5 GO:0060789 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) hair follicle placode formation(GO:0060789) regulation of parathyroid hormone secretion(GO:2000828)
0.7 0.7 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.7 5.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.7 5.0 GO:0015871 choline transport(GO:0015871)
0.7 3.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.7 2.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.7 4.2 GO:0045176 apical protein localization(GO:0045176)
0.7 5.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.7 3.5 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.7 7.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 5.6 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.7 1.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.7 3.5 GO:0032095 regulation of response to food(GO:0032095)
0.7 2.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.7 2.0 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.7 3.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 8.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.7 2.7 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.7 6.0 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.7 1.3 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.7 2.0 GO:0021759 globus pallidus development(GO:0021759)
0.7 13.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.7 13.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.7 5.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.7 13.2 GO:1900274 regulation of phospholipase C activity(GO:1900274)
0.7 2.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.7 23.1 GO:0010107 potassium ion import(GO:0010107)
0.7 6.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.7 3.9 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.7 9.1 GO:0070723 response to cholesterol(GO:0070723)
0.6 3.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.6 15.6 GO:0030488 tRNA methylation(GO:0030488)
0.6 1.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.6 6.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.6 1.9 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.6 0.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.6 1.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.6 2.6 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.6 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.6 2.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.6 6.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.6 3.2 GO:0010044 response to aluminum ion(GO:0010044)
0.6 4.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.6 6.9 GO:0005513 detection of calcium ion(GO:0005513)
0.6 15.0 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.6 1.9 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.6 39.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.6 6.9 GO:0035330 regulation of hippo signaling(GO:0035330)
0.6 6.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.6 6.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.6 11.6 GO:0045109 intermediate filament organization(GO:0045109)
0.6 4.9 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.6 4.8 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.6 2.4 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.6 5.4 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.6 35.3 GO:0007422 peripheral nervous system development(GO:0007422)
0.6 6.0 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.6 5.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.6 3.6 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.6 2.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.6 1.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.6 2.9 GO:0042908 xenobiotic transport(GO:0042908)
0.6 2.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.6 8.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.6 1.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6 0.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.6 0.6 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.6 5.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.6 3.9 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.6 5.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.6 3.9 GO:0051414 response to cortisol(GO:0051414)
0.6 1.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.6 5.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.6 2.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.6 5.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.6 6.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.6 1.7 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.5 1.6 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5 3.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.5 7.5 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.5 3.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.5 1.1 GO:1902713 regulation of interferon-gamma secretion(GO:1902713) positive regulation of interferon-gamma secretion(GO:1902715)
0.5 4.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5 8.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.5 1.6 GO:0070269 pyroptosis(GO:0070269)
0.5 36.4 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.5 6.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.5 3.6 GO:0035909 aorta morphogenesis(GO:0035909)
0.5 1.0 GO:0015793 glycerol transport(GO:0015793)
0.5 4.1 GO:0045730 respiratory burst(GO:0045730)
0.5 1.0 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.5 15.2 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.5 3.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.5 3.0 GO:0006196 AMP catabolic process(GO:0006196)
0.5 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.5 2.0 GO:0006408 snRNA export from nucleus(GO:0006408)
0.5 9.4 GO:0097502 mannosylation(GO:0097502)
0.5 3.0 GO:0008218 bioluminescence(GO:0008218)
0.5 3.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.5 2.0 GO:0061107 seminal vesicle development(GO:0061107)
0.5 4.9 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.5 2.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.5 1.4 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.5 1.0 GO:0015824 proline transport(GO:0015824)
0.5 1.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.5 1.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.5 6.0 GO:0014047 glutamate secretion(GO:0014047)
0.5 2.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.5 43.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.5 5.5 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.5 5.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.5 22.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.5 1.8 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.5 3.6 GO:0050798 activated T cell proliferation(GO:0050798)
0.5 0.9 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.4 28.8 GO:0006970 response to osmotic stress(GO:0006970)
0.4 2.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 3.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 10.3 GO:0090383 phagosome acidification(GO:0090383)
0.4 8.0 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.4 4.9 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.4 4.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 9.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.4 5.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.4 0.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.4 1.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 9.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.4 3.4 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.4 3.8 GO:0019228 neuronal action potential(GO:0019228)
0.4 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.4 5.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 6.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.4 7.9 GO:0015695 organic cation transport(GO:0015695)
0.4 2.5 GO:0036010 protein localization to endosome(GO:0036010)
0.4 2.5 GO:0045023 G0 to G1 transition(GO:0045023)
0.4 6.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.4 2.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 0.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.4 5.3 GO:0051602 response to electrical stimulus(GO:0051602)
0.4 3.7 GO:0007220 Notch receptor processing(GO:0007220)
0.4 0.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.4 7.1 GO:0097352 autophagosome maturation(GO:0097352)
0.4 2.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.4 25.9 GO:0005977 glycogen metabolic process(GO:0005977)
0.4 1.9 GO:0006063 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)
0.4 3.1 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.4 14.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.4 6.8 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.4 10.9 GO:0006400 tRNA modification(GO:0006400)
0.4 2.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.4 2.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 1.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 0.7 GO:0071609 chemokine (C-C motif) ligand 5 production(GO:0071609)
0.4 3.6 GO:0035587 purinergic receptor signaling pathway(GO:0035587)
0.4 0.4 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 1.7 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.3 0.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 4.8 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.3 4.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.3 0.7 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.3 1.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 3.7 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.3 4.6 GO:0098868 bone growth(GO:0098868)
0.3 1.3 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.3 1.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 7.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 2.6 GO:0001945 lymph vessel development(GO:0001945)
0.3 0.9 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 1.5 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.3 35.5 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.3 3.0 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.3 0.9 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 3.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.3 152.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.3 0.6 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.3 4.5 GO:0048753 pigment granule organization(GO:0048753)
0.3 8.0 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.3 0.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.3 1.7 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.9 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.3 1.9 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.3 3.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.3 1.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 2.0 GO:0002021 response to dietary excess(GO:0002021)
0.3 2.0 GO:0033344 cholesterol efflux(GO:0033344)
0.3 1.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 1.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.3 3.0 GO:0006067 ethanol metabolic process(GO:0006067)
0.2 0.7 GO:0001927 exocyst assembly(GO:0001927)
0.2 4.9 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.2 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.7 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.2 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.5 GO:0072132 mesenchyme morphogenesis(GO:0072132)
0.2 3.0 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.2 0.9 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 1.5 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.2 0.4 GO:0048840 otolith development(GO:0048840)
0.2 0.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 1.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2 1.4 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.2 2.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.2 1.0 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 0.8 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.2 3.4 GO:0009880 embryonic pattern specification(GO:0009880)
0.2 0.8 GO:0048539 bone marrow development(GO:0048539)
0.2 1.8 GO:1901203 positive regulation of extracellular matrix assembly(GO:1901203)
0.2 1.4 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.2 1.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 1.0 GO:0045655 regulation of monocyte differentiation(GO:0045655)
0.2 1.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 1.4 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.3 GO:0051255 spindle midzone assembly(GO:0051255)
0.2 3.0 GO:0003310 pancreatic A cell differentiation(GO:0003310) pancreatic A cell development(GO:0003322)
0.2 0.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.3 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.2 1.5 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.2 0.2 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.2 0.6 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2 1.6 GO:0046710 GDP metabolic process(GO:0046710)
0.2 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.1 12.8 GO:0048515 spermatid differentiation(GO:0048515)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.8 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.1 1.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 3.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.5 GO:0042220 response to cocaine(GO:0042220)
0.1 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 10.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.1 2.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.0 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.1 0.4 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.1 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) serotonin receptor signaling pathway(GO:0007210)
0.1 0.2 GO:0002363 alpha-beta T cell lineage commitment(GO:0002363)
0.1 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.9 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.4 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.4 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0070528 protein kinase C signaling(GO:0070528)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
19.1 76.6 GO:0070695 FHF complex(GO:0070695)
14.6 87.8 GO:0033269 internode region of axon(GO:0033269)
12.8 102.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
12.3 98.3 GO:0045179 apical cortex(GO:0045179)
11.3 90.6 GO:0035976 AP1 complex(GO:0035976)
11.3 90.4 GO:0000138 Golgi trans cisterna(GO:0000138)
11.1 44.3 GO:0005602 complement component C1 complex(GO:0005602)
11.0 43.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
10.0 10.0 GO:1902710 GABA receptor complex(GO:1902710)
9.9 29.8 GO:0000333 telomerase catalytic core complex(GO:0000333)
9.9 29.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
9.4 75.6 GO:0061689 tricellular tight junction(GO:0061689)
8.7 69.4 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
8.5 8.5 GO:0033093 Weibel-Palade body(GO:0033093)
8.0 32.0 GO:0071546 pi-body(GO:0071546)
7.3 145.9 GO:0033270 paranode region of axon(GO:0033270)
7.2 93.5 GO:0042583 chromaffin granule(GO:0042583)
7.0 77.3 GO:0033010 paranodal junction(GO:0033010)
6.5 39.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
6.1 30.7 GO:0036128 CatSper complex(GO:0036128)
6.1 6.1 GO:0097449 glial cell projection(GO:0097386) astrocyte projection(GO:0097449)
6.1 18.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
6.1 30.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
6.0 24.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
6.0 18.0 GO:0032426 stereocilium tip(GO:0032426)
5.2 15.7 GO:0070701 mucus layer(GO:0070701)
5.2 72.1 GO:0097433 dense body(GO:0097433)
5.1 81.8 GO:0097512 cardiac myofibril(GO:0097512)
5.1 127.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
5.0 15.0 GO:0043159 acrosomal matrix(GO:0043159)
4.8 4.8 GO:0031088 platelet dense granule membrane(GO:0031088)
4.8 23.8 GO:1990031 pinceau fiber(GO:1990031)
4.7 14.0 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
4.6 13.9 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
4.6 27.4 GO:1990769 proximal neuron projection(GO:1990769)
4.6 45.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
4.5 9.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
4.5 58.3 GO:0060077 inhibitory synapse(GO:0060077)
4.4 17.6 GO:1990879 CST complex(GO:1990879)
4.4 60.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
4.3 43.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
4.3 25.6 GO:0005594 collagen type IX trimer(GO:0005594)
4.2 8.5 GO:0005593 FACIT collagen trimer(GO:0005593)
4.2 12.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
4.2 20.8 GO:0019815 B cell receptor complex(GO:0019815)
4.1 231.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
4.0 24.0 GO:0001940 male pronucleus(GO:0001940)
3.9 19.7 GO:0032280 symmetric synapse(GO:0032280)
3.9 23.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
3.9 19.3 GO:0002080 acrosomal membrane(GO:0002080)
3.8 23.0 GO:0045298 tubulin complex(GO:0045298)
3.8 71.7 GO:0042613 MHC class II protein complex(GO:0042613)
3.8 18.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
3.7 29.7 GO:0097450 astrocyte end-foot(GO:0097450)
3.6 14.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
3.5 31.4 GO:0097208 alveolar lamellar body(GO:0097208)
3.5 76.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
3.4 10.2 GO:0032009 early phagosome(GO:0032009)
3.3 9.9 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
3.2 18.9 GO:0030008 TRAPP complex(GO:0030008)
3.1 15.6 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
3.1 9.3 GO:0098536 deuterosome(GO:0098536)
3.0 21.1 GO:0032021 NELF complex(GO:0032021)
3.0 35.5 GO:0042788 polysomal ribosome(GO:0042788)
3.0 8.9 GO:0032437 cuticular plate(GO:0032437)
2.9 17.6 GO:0005879 axonemal microtubule(GO:0005879)
2.9 125.6 GO:0031430 M band(GO:0031430)
2.9 54.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
2.9 37.2 GO:0031045 dense core granule(GO:0031045)
2.8 14.2 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
2.8 19.9 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
2.8 31.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
2.8 5.7 GO:0002139 stereocilia coupling link(GO:0002139)
2.8 11.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
2.8 36.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.8 16.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.8 33.3 GO:0097427 microtubule bundle(GO:0097427)
2.7 22.0 GO:0032593 insulin-responsive compartment(GO:0032593)
2.7 2.7 GO:0099634 postsynaptic specialization membrane(GO:0099634)
2.7 67.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
2.7 45.7 GO:0042627 chylomicron(GO:0042627)
2.7 10.6 GO:0044327 dendritic spine head(GO:0044327)
2.6 18.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
2.6 7.9 GO:0036398 TCR signalosome(GO:0036398)
2.6 10.4 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
2.6 13.0 GO:0089701 U2AF(GO:0089701)
2.6 217.7 GO:0034707 chloride channel complex(GO:0034707)
2.6 43.9 GO:0016461 unconventional myosin complex(GO:0016461)
2.5 60.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
2.5 101.0 GO:0001533 cornified envelope(GO:0001533)
2.4 41.6 GO:0005861 troponin complex(GO:0005861)
2.4 9.8 GO:0030897 HOPS complex(GO:0030897)
2.4 77.9 GO:0043235 receptor complex(GO:0043235)
2.4 48.4 GO:0005721 pericentric heterochromatin(GO:0005721)
2.4 58.0 GO:0005720 nuclear heterochromatin(GO:0005720)
2.4 21.7 GO:0035253 ciliary rootlet(GO:0035253)
2.4 12.1 GO:0070847 core mediator complex(GO:0070847)
2.4 49.8 GO:0032591 dendritic spine membrane(GO:0032591)
2.4 68.8 GO:0005859 muscle myosin complex(GO:0005859)
2.4 16.6 GO:1990745 EARP complex(GO:1990745)
2.4 172.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
2.4 7.1 GO:0032116 SMC loading complex(GO:0032116)
2.3 7.0 GO:0043293 apoptosome(GO:0043293)
2.3 16.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
2.3 6.9 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.2 8.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.2 31.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
2.2 11.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
2.2 10.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
2.2 39.2 GO:0031089 platelet dense granule lumen(GO:0031089)
2.2 30.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
2.1 14.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
2.1 31.9 GO:0031083 BLOC-1 complex(GO:0031083)
2.1 4.2 GO:0044326 dendritic spine neck(GO:0044326)
2.1 6.3 GO:0005760 gamma DNA polymerase complex(GO:0005760)
2.1 45.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
2.1 10.3 GO:0017119 Golgi transport complex(GO:0017119)
2.1 88.3 GO:0048786 presynaptic active zone(GO:0048786)
2.0 18.4 GO:0044294 dendritic growth cone(GO:0044294)
2.0 6.0 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
2.0 12.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
1.9 5.8 GO:0000801 central element(GO:0000801)
1.9 19.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.9 15.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.9 11.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.9 132.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.9 7.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
1.8 3.7 GO:1990635 proximal dendrite(GO:1990635)
1.8 20.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.8 25.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.8 18.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
1.8 30.7 GO:0097440 apical dendrite(GO:0097440)
1.8 10.8 GO:0031501 mannosyltransferase complex(GO:0031501)
1.8 18.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
1.8 8.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.8 24.9 GO:0043083 synaptic cleft(GO:0043083)
1.8 140.1 GO:0016328 lateral plasma membrane(GO:0016328)
1.7 26.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.7 7.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.7 50.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.7 17.3 GO:0005614 interstitial matrix(GO:0005614)
1.7 13.8 GO:0005587 collagen type IV trimer(GO:0005587)
1.7 25.6 GO:0044447 axoneme part(GO:0044447)
1.7 38.2 GO:0031528 microvillus membrane(GO:0031528)
1.7 3.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
1.7 82.6 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
1.6 100.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.6 3.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
1.6 11.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.6 8.0 GO:0032302 MutSbeta complex(GO:0032302)
1.6 3.2 GO:1990393 3M complex(GO:1990393)
1.6 6.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.6 9.6 GO:0032010 phagolysosome(GO:0032010)
1.6 4.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.6 8.0 GO:0005713 recombination nodule(GO:0005713)
1.6 11.1 GO:0005921 gap junction(GO:0005921)
1.6 17.3 GO:0042587 glycogen granule(GO:0042587)
1.6 67.0 GO:0005902 microvillus(GO:0005902)
1.5 37.1 GO:0008305 integrin complex(GO:0008305)
1.5 7.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.5 29.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
1.5 10.6 GO:0097209 epidermal lamellar body(GO:0097209)
1.5 4.5 GO:0044609 DBIRD complex(GO:0044609)
1.5 7.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.5 68.1 GO:0097546 ciliary base(GO:0097546)
1.5 50.1 GO:0001917 photoreceptor inner segment(GO:0001917)
1.5 27.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.5 4.4 GO:0016013 syntrophin complex(GO:0016013)
1.4 13.0 GO:0005845 mRNA cap binding complex(GO:0005845)
1.4 22.9 GO:0005652 nuclear lamina(GO:0005652)
1.4 5.7 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
1.4 18.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.4 2.8 GO:0001939 female pronucleus(GO:0001939)
1.4 5.6 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.4 78.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.3 2.7 GO:0043291 RAVE complex(GO:0043291)
1.3 4.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.3 6.7 GO:0032449 CBM complex(GO:0032449)
1.3 21.2 GO:0005922 connexon complex(GO:0005922)
1.3 43.0 GO:0042629 mast cell granule(GO:0042629)
1.3 131.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
1.3 6.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.3 16.7 GO:0035579 specific granule membrane(GO:0035579)
1.3 7.6 GO:0033179 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.2 3.7 GO:0072536 interleukin-23 receptor complex(GO:0072536)
1.2 33.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.2 3.6 GO:0016938 kinesin I complex(GO:0016938)
1.2 7.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.2 3.6 GO:0035189 Rb-E2F complex(GO:0035189)
1.2 14.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.2 6.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
1.2 7.1 GO:0070545 PeBoW complex(GO:0070545)
1.2 2.4 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
1.2 13.0 GO:0035102 PRC1 complex(GO:0035102)
1.2 6.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.1 125.0 GO:0043204 perikaryon(GO:0043204)
1.1 7.9 GO:0061700 GATOR2 complex(GO:0061700)
1.1 14.7 GO:0005833 hemoglobin complex(GO:0005833)
1.1 23.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.1 6.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.1 3.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.1 152.5 GO:0072562 blood microparticle(GO:0072562)
1.1 14.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.1 6.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.1 159.5 GO:0031225 anchored component of membrane(GO:0031225)
1.1 37.0 GO:0043198 dendritic shaft(GO:0043198)
1.0 7.3 GO:0043679 axon terminus(GO:0043679)
1.0 9.3 GO:0070652 HAUS complex(GO:0070652)
1.0 183.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.0 242.7 GO:0016323 basolateral plasma membrane(GO:0016323)
1.0 14.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.0 96.9 GO:0005796 Golgi lumen(GO:0005796)
1.0 33.7 GO:1904115 axon cytoplasm(GO:1904115)
1.0 19.4 GO:0031594 neuromuscular junction(GO:0031594)
1.0 6.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.9 38.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.9 7.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.9 2.7 GO:0034657 GID complex(GO:0034657)
0.9 8.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.9 33.1 GO:0030175 filopodium(GO:0030175)
0.9 8.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.9 14.3 GO:0000800 lateral element(GO:0000800)
0.9 7.1 GO:0097225 sperm midpiece(GO:0097225)
0.9 4.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.9 29.2 GO:0016235 aggresome(GO:0016235)
0.9 4.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.9 6.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.8 4.2 GO:1902560 GMP reductase complex(GO:1902560)
0.8 1.7 GO:0016939 kinesin II complex(GO:0016939)
0.8 4.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.8 20.8 GO:0001772 immunological synapse(GO:0001772)
0.8 2.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.8 36.4 GO:0031526 brush border membrane(GO:0031526)
0.8 3.2 GO:0030057 desmosome(GO:0030057)
0.8 17.1 GO:0030673 axolemma(GO:0030673)
0.8 107.5 GO:0030427 site of polarized growth(GO:0030427)
0.8 2.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.8 42.6 GO:0005811 lipid particle(GO:0005811)
0.7 12.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.7 2.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.7 2.9 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.7 2.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.7 2.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.7 2.8 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.7 3.5 GO:0033391 chromatoid body(GO:0033391)
0.7 29.5 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.7 12.9 GO:0031904 endosome lumen(GO:0031904)
0.7 4.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.7 4.0 GO:0000243 commitment complex(GO:0000243)
0.7 4.0 GO:0005577 fibrinogen complex(GO:0005577)
0.7 20.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 39.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.6 29.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.6 2.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.6 12.8 GO:0000421 autophagosome membrane(GO:0000421)
0.6 5.5 GO:0097452 GAIT complex(GO:0097452)
0.6 9.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.6 1.8 GO:0005899 insulin receptor complex(GO:0005899)
0.6 61.1 GO:0005802 trans-Golgi network(GO:0005802)
0.6 6.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.6 76.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.5 7.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5 2.7 GO:0005579 membrane attack complex(GO:0005579)
0.5 15.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.5 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.5 7.3 GO:0000242 pericentriolar material(GO:0000242)
0.5 4.1 GO:0071953 elastic fiber(GO:0071953)
0.5 2.0 GO:0035363 histone locus body(GO:0035363)
0.5 598.1 GO:0005615 extracellular space(GO:0005615)
0.5 4.9 GO:0060076 excitatory synapse(GO:0060076)
0.5 4.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.5 0.9 GO:1902636 kinociliary basal body(GO:1902636)
0.4 9.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.4 1694.1 GO:0031224 intrinsic component of membrane(GO:0031224)
0.4 1.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 3.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 1.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.4 2.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 9.3 GO:0008021 synaptic vesicle(GO:0008021)
0.4 1.8 GO:0045180 basal cortex(GO:0045180)
0.3 4.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 0.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3 0.9 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.3 13.3 GO:0030133 transport vesicle(GO:0030133)
0.3 3.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 2.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 2.3 GO:0070552 BRISC complex(GO:0070552)
0.2 0.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 2.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 10.4 GO:0030424 axon(GO:0030424)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.4 GO:0000786 nucleosome(GO:0000786)
0.1 2.5 GO:0030315 T-tubule(GO:0030315)
0.1 0.7 GO:0000145 exocyst(GO:0000145)
0.1 0.9 GO:0071437 invadopodium(GO:0071437)
0.1 2.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.8 GO:0000791 euchromatin(GO:0000791)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 7.2 GO:0045202 synapse(GO:0045202)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
17.0 50.9 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
16.0 64.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
15.6 46.8 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
14.3 171.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
14.3 57.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
12.4 74.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
12.4 37.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
11.5 46.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
11.0 154.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
10.8 43.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
10.6 31.9 GO:0031849 olfactory receptor binding(GO:0031849)
10.4 41.6 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
10.0 30.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
9.8 39.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
9.7 29.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
9.5 28.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
9.4 28.3 GO:0004040 amidase activity(GO:0004040)
9.4 28.2 GO:0036055 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
9.3 18.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
9.3 18.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
9.2 36.8 GO:0004341 gluconolactonase activity(GO:0004341)
8.9 26.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
8.9 80.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
8.8 61.6 GO:0030492 hemoglobin binding(GO:0030492)
8.6 25.9 GO:0031696 alpha-2C adrenergic receptor binding(GO:0031696)
8.4 8.4 GO:0001851 complement component C3b binding(GO:0001851)
8.3 8.3 GO:0050682 AF-2 domain binding(GO:0050682)
8.3 33.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
8.2 65.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
7.9 31.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
7.7 30.7 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
7.3 29.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
7.3 43.6 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
7.2 21.5 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
7.1 28.3 GO:0004773 steryl-sulfatase activity(GO:0004773)
7.0 42.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
7.0 105.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
6.9 48.6 GO:0042289 MHC class II protein binding(GO:0042289)
6.9 27.7 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
6.6 329.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
6.5 26.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
6.5 90.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
6.3 18.9 GO:0008431 vitamin E binding(GO:0008431)
6.3 18.8 GO:0031687 A2A adenosine receptor binding(GO:0031687)
6.1 24.4 GO:0018271 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
6.1 42.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
6.0 18.1 GO:0001601 peptide YY receptor activity(GO:0001601)
6.0 12.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
6.0 24.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
6.0 107.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
5.9 17.8 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
5.8 17.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
5.8 23.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
5.8 52.2 GO:0043426 MRF binding(GO:0043426)
5.8 23.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
5.8 28.9 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
5.7 17.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
5.7 17.1 GO:0034046 poly(G) binding(GO:0034046)
5.7 17.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
5.6 33.8 GO:0030172 troponin C binding(GO:0030172)
5.6 22.5 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
5.6 44.7 GO:0005000 vasopressin receptor activity(GO:0005000)
5.6 27.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
5.5 66.1 GO:0016594 glycine binding(GO:0016594)
5.4 16.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
5.4 48.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
5.4 21.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
5.4 16.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
5.4 16.2 GO:0070052 collagen V binding(GO:0070052)
5.4 21.5 GO:0047708 biotinidase activity(GO:0047708)
5.4 32.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
5.3 26.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
5.2 20.8 GO:0031716 calcitonin receptor binding(GO:0031716)
5.2 15.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
5.1 20.6 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
5.1 10.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
5.1 15.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
5.0 49.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
5.0 20.0 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
5.0 14.9 GO:0032093 SAM domain binding(GO:0032093)
4.9 19.4 GO:0042015 interleukin-20 binding(GO:0042015)
4.8 43.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
4.8 76.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
4.8 28.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
4.8 81.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
4.6 9.3 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
4.6 23.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
4.6 36.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
4.5 13.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
4.5 18.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
4.5 27.2 GO:0061665 SUMO ligase activity(GO:0061665)
4.5 67.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
4.5 36.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
4.5 26.9 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
4.5 13.4 GO:0008502 melatonin receptor activity(GO:0008502)
4.5 89.3 GO:0051787 misfolded protein binding(GO:0051787)
4.5 102.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
4.4 13.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
4.4 17.4 GO:0032184 SUMO polymer binding(GO:0032184)
4.4 61.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
4.3 30.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
4.3 17.3 GO:0032810 sterol response element binding(GO:0032810)
4.3 21.6 GO:0030348 syntaxin-3 binding(GO:0030348)
4.3 12.9 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
4.3 51.6 GO:0005344 oxygen transporter activity(GO:0005344)
4.3 25.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
4.3 17.0 GO:0031433 telethonin binding(GO:0031433)
4.2 33.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
4.1 45.5 GO:0036310 annealing helicase activity(GO:0036310)
4.1 16.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
4.1 32.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
4.1 20.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
4.1 20.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
4.1 12.2 GO:0004912 interleukin-3 receptor activity(GO:0004912)
4.0 36.3 GO:0034235 GPI anchor binding(GO:0034235)
4.0 20.1 GO:0050436 microfibril binding(GO:0050436)
4.0 28.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
4.0 19.9 GO:0070097 delta-catenin binding(GO:0070097)
4.0 4.0 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
4.0 35.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
4.0 98.8 GO:0017075 syntaxin-1 binding(GO:0017075)
3.9 31.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
3.9 55.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
3.9 15.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
3.9 19.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.9 23.4 GO:0008142 oxysterol binding(GO:0008142)
3.9 7.8 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
3.9 85.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
3.9 54.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
3.9 88.8 GO:0031005 filamin binding(GO:0031005)
3.9 50.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
3.9 7.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.8 42.3 GO:0033691 sialic acid binding(GO:0033691)
3.8 95.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
3.8 19.0 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
3.8 18.9 GO:0097603 temperature-gated ion channel activity(GO:0097603)
3.7 48.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
3.7 100.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
3.7 22.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
3.7 37.0 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
3.7 14.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
3.7 102.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
3.7 11.0 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
3.7 25.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
3.6 7.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
3.6 14.4 GO:0004925 prolactin receptor activity(GO:0004925)
3.6 10.8 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
3.6 10.8 GO:0033142 progesterone receptor binding(GO:0033142)
3.6 56.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
3.5 24.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
3.5 17.6 GO:1990239 steroid hormone binding(GO:1990239)
3.5 14.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
3.5 34.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
3.5 20.9 GO:0008420 CTD phosphatase activity(GO:0008420)
3.5 10.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
3.5 17.3 GO:0004771 sterol esterase activity(GO:0004771)
3.5 13.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
3.5 13.8 GO:0001855 complement component C4b binding(GO:0001855)
3.5 65.6 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
3.4 10.3 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
3.4 10.2 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
3.4 10.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
3.4 16.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
3.3 10.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
3.3 13.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
3.3 23.3 GO:0001515 opioid peptide activity(GO:0001515)
3.3 10.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
3.3 16.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
3.3 26.2 GO:0004111 creatine kinase activity(GO:0004111)
3.3 9.8 GO:0005137 interleukin-5 receptor binding(GO:0005137)
3.3 29.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
3.3 22.8 GO:0005499 vitamin D binding(GO:0005499)
3.3 13.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.3 13.0 GO:0099609 microtubule lateral binding(GO:0099609)
3.3 13.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
3.2 199.0 GO:0030507 spectrin binding(GO:0030507)
3.2 22.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
3.1 22.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
3.1 9.4 GO:0016422 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
3.1 28.0 GO:0034711 inhibin binding(GO:0034711)
3.1 52.8 GO:0045294 alpha-catenin binding(GO:0045294)
3.1 3.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
3.1 15.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
3.1 58.4 GO:0038191 neuropilin binding(GO:0038191)
3.0 33.5 GO:0032051 clathrin light chain binding(GO:0032051)
3.0 21.2 GO:0000182 rDNA binding(GO:0000182)
3.0 12.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
3.0 11.9 GO:0005163 nerve growth factor receptor binding(GO:0005163)
3.0 17.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
3.0 11.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
3.0 8.9 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.9 103.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
2.9 41.2 GO:0031419 cobalamin binding(GO:0031419)
2.9 317.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.9 143.8 GO:0030552 cAMP binding(GO:0030552)
2.9 14.6 GO:0004447 iodide peroxidase activity(GO:0004447)
2.9 8.8 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
2.9 63.6 GO:0050321 tau-protein kinase activity(GO:0050321)
2.8 53.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.8 28.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
2.8 8.5 GO:0005174 CD40 receptor binding(GO:0005174)
2.8 16.9 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.8 16.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
2.8 14.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.8 8.4 GO:0001007 transcription factor activity, core RNA polymerase III binding(GO:0000995) transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
2.8 33.5 GO:0038132 neuregulin binding(GO:0038132)
2.8 13.9 GO:0004994 somatostatin receptor activity(GO:0004994)
2.8 8.3 GO:0035473 lipase binding(GO:0035473)
2.8 8.3 GO:0070573 metallodipeptidase activity(GO:0070573)
2.8 13.8 GO:0004995 tachykinin receptor activity(GO:0004995)
2.7 8.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
2.7 8.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.7 2.7 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
2.7 8.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
2.7 16.2 GO:0051373 FATZ binding(GO:0051373)
2.7 24.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
2.7 18.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
2.7 2.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
2.7 26.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
2.7 18.6 GO:1904288 BAT3 complex binding(GO:1904288)
2.7 8.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
2.7 10.6 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
2.7 15.9 GO:0004359 glutaminase activity(GO:0004359)
2.6 7.9 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
2.6 28.9 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
2.6 7.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
2.6 5.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
2.6 13.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
2.6 7.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
2.6 10.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.6 28.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
2.5 5.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
2.5 20.4 GO:0038064 collagen receptor activity(GO:0038064)
2.5 7.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
2.5 45.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
2.5 27.7 GO:0004645 phosphorylase activity(GO:0004645)
2.5 10.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
2.5 10.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.5 10.0 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.5 7.5 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) ciliary neurotrophic factor binding(GO:0070119)
2.5 42.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
2.5 7.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
2.5 7.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
2.5 27.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
2.5 19.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
2.5 7.4 GO:0004336 galactosylceramidase activity(GO:0004336)
2.5 9.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
2.4 7.3 GO:0003916 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
2.4 9.6 GO:0031893 vasopressin receptor binding(GO:0031893)
2.4 31.3 GO:0070700 BMP receptor binding(GO:0070700)
2.4 16.9 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
2.4 2.4 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
2.4 45.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
2.4 26.3 GO:0048406 nerve growth factor binding(GO:0048406)
2.4 4.7 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
2.3 14.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
2.3 9.3 GO:0002046 opsin binding(GO:0002046)
2.3 7.0 GO:0035375 zymogen binding(GO:0035375)
2.3 14.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
2.3 11.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.3 9.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
2.3 18.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.3 15.9 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
2.3 63.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
2.2 6.7 GO:0045322 unmethylated CpG binding(GO:0045322)
2.2 13.5 GO:0022821 potassium ion antiporter activity(GO:0022821)
2.2 35.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
2.2 8.9 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.2 6.7 GO:0005502 11-cis retinal binding(GO:0005502)
2.2 11.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
2.2 13.2 GO:0031685 adenosine receptor binding(GO:0031685)
2.2 13.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
2.2 11.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
2.2 8.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
2.2 8.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
2.2 10.8 GO:0004522 ribonuclease A activity(GO:0004522)
2.2 6.5 GO:0043121 neurotrophin receptor activity(GO:0005030) neurotrophin binding(GO:0043121)
2.2 25.9 GO:0042577 lipid phosphatase activity(GO:0042577)
2.1 8.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
2.1 10.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
2.1 6.4 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
2.1 4.2 GO:0032090 Pyrin domain binding(GO:0032090)
2.1 116.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
2.1 6.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.1 10.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
2.1 6.2 GO:0036505 prosaposin receptor activity(GO:0036505)
2.1 29.1 GO:0019992 diacylglycerol binding(GO:0019992)
2.0 2.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
2.0 22.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
2.0 6.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.0 2.0 GO:0071837 HMG box domain binding(GO:0071837)
2.0 16.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
2.0 12.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
2.0 15.7 GO:0019215 intermediate filament binding(GO:0019215)
2.0 3.9 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
2.0 15.7 GO:0042609 CD4 receptor binding(GO:0042609)
1.9 233.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
1.9 23.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.9 7.7 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.9 7.7 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
1.9 5.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.9 38.3 GO:0044548 S100 protein binding(GO:0044548)
1.9 1.9 GO:0015116 sulfate transmembrane transporter activity(GO:0015116)
1.9 32.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
1.9 13.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
1.9 7.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
1.9 14.9 GO:0015232 heme transporter activity(GO:0015232)
1.8 9.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
1.8 9.2 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
1.8 38.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.8 508.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.8 32.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
1.8 124.0 GO:0070412 R-SMAD binding(GO:0070412)
1.8 7.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
1.8 7.2 GO:0061714 folic acid receptor activity(GO:0061714)
1.8 7.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
1.8 21.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.8 14.2 GO:0015643 toxic substance binding(GO:0015643)
1.8 21.0 GO:0031014 troponin T binding(GO:0031014)
1.7 15.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.7 53.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.7 13.8 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.7 10.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
1.7 6.8 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
1.7 44.1 GO:0050780 dopamine receptor binding(GO:0050780)
1.7 10.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.7 20.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
1.7 11.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.7 8.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.7 5.0 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.7 199.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
1.7 8.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.7 102.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
1.6 47.8 GO:0070566 adenylyltransferase activity(GO:0070566)
1.6 6.6 GO:0016841 ammonia-lyase activity(GO:0016841)
1.6 13.2 GO:0043274 phospholipase binding(GO:0043274)
1.6 24.4 GO:0005243 gap junction channel activity(GO:0005243)
1.6 13.0 GO:0017127 cholesterol transporter activity(GO:0017127)
1.6 19.4 GO:0046870 cadmium ion binding(GO:0046870)
1.6 51.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.6 14.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.6 48.0 GO:0005212 structural constituent of eye lens(GO:0005212)
1.6 9.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.6 8.0 GO:0004966 galanin receptor activity(GO:0004966)
1.6 4.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.6 4.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
1.6 3.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.6 17.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.6 15.9 GO:0030215 semaphorin receptor binding(GO:0030215)
1.6 33.3 GO:0070300 phosphatidic acid binding(GO:0070300)
1.6 9.4 GO:0008172 S-methyltransferase activity(GO:0008172)
1.6 6.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.6 7.9 GO:0008410 CoA-transferase activity(GO:0008410)
1.6 37.4 GO:0030506 ankyrin binding(GO:0030506)
1.6 3.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.5 41.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
1.5 61.7 GO:0070840 dynein complex binding(GO:0070840)
1.5 7.7 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.5 15.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.5 16.8 GO:0035325 Toll-like receptor binding(GO:0035325)
1.5 10.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.5 22.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
1.5 26.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.5 17.9 GO:0032395 MHC class II receptor activity(GO:0032395)
1.5 4.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.5 33.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
1.5 5.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.4 44.9 GO:0043015 gamma-tubulin binding(GO:0043015)
1.4 5.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
1.4 5.8 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
1.4 12.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.4 7.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.4 11.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.4 19.8 GO:0019957 C-C chemokine binding(GO:0019957)
1.4 4.2 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
1.4 7.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
1.4 22.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.4 7.0 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.4 22.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
1.4 37.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.4 5.5 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
1.4 4.1 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
1.4 13.6 GO:0031994 insulin-like growth factor I binding(GO:0031994)
1.4 4.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.4 4.1 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
1.4 9.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.4 2.7 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
1.3 35.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.3 20.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.3 16.1 GO:0031432 titin binding(GO:0031432)
1.3 6.6 GO:0004803 transposase activity(GO:0004803)
1.3 10.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
1.3 15.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.3 3.9 GO:0015265 urea channel activity(GO:0015265)
1.3 6.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.3 3.9 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
1.3 3.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.3 2.6 GO:0055102 lipase inhibitor activity(GO:0055102)
1.3 3.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.3 16.6 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
1.3 29.1 GO:0022839 ion gated channel activity(GO:0022839)
1.3 7.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.3 7.5 GO:0015057 thrombin receptor activity(GO:0015057)
1.3 6.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
1.2 7.5 GO:0003796 lysozyme activity(GO:0003796)
1.2 1.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.2 3.7 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.2 11.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.2 11.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.2 1.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.2 3.7 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
1.2 4.9 GO:0097001 ceramide binding(GO:0097001)
1.2 3.6 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.2 8.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
1.2 4.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.2 4.8 GO:0070728 leucine binding(GO:0070728)
1.2 10.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.2 123.5 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
1.2 7.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
1.2 15.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
1.2 29.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
1.1 13.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.1 8.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.1 4.5 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
1.1 28.4 GO:0004806 triglyceride lipase activity(GO:0004806)
1.1 25.8 GO:0002162 dystroglycan binding(GO:0002162)
1.1 3.4 GO:0004977 melanocortin receptor activity(GO:0004977)
1.1 6.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.1 101.9 GO:0004984 olfactory receptor activity(GO:0004984)
1.1 3.3 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
1.1 2.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.1 6.6 GO:0097643 amylin receptor activity(GO:0097643)
1.1 14.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
1.1 14.2 GO:0005523 tropomyosin binding(GO:0005523)
1.1 7.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
1.1 7.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.1 2.2 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
1.1 4.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.1 3.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.1 7.5 GO:0039706 co-receptor binding(GO:0039706)
1.1 2.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
1.1 45.1 GO:0043621 protein self-association(GO:0043621)
1.1 3.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
1.1 3.2 GO:0031862 prostanoid receptor binding(GO:0031862)
1.1 10.7 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.1 17.0 GO:0008327 methyl-CpG binding(GO:0008327)
1.1 8.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
1.1 5.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
1.1 13.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.0 5.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
1.0 16.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
1.0 13.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
1.0 3.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
1.0 3.1 GO:0005055 laminin receptor activity(GO:0005055)
1.0 3.0 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.0 3.0 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.0 7.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.0 12.0 GO:0051184 cofactor transporter activity(GO:0051184)
1.0 4.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
1.0 4.9 GO:0098821 BMP receptor activity(GO:0098821)
1.0 6.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.0 3.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.0 5.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.0 2.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.0 40.1 GO:0008009 chemokine activity(GO:0008009)
1.0 4.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
1.0 3.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.0 4.9 GO:0016936 galactoside binding(GO:0016936)
1.0 4.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.0 8.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
1.0 5.8 GO:0004046 aminoacylase activity(GO:0004046)
1.0 3.9 GO:0070404 NADH binding(GO:0070404)
1.0 8.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
1.0 45.7 GO:0005254 chloride channel activity(GO:0005254)
1.0 11.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.9 12.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.9 1.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.9 7.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.9 1.9 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.9 5.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.9 5.6 GO:0008430 selenium binding(GO:0008430)
0.9 6.5 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.9 2.8 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.9 16.6 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217)
0.9 10.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.9 87.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.9 16.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.9 10.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.9 78.7 GO:0005179 hormone activity(GO:0005179)
0.9 1.8 GO:0004875 complement receptor activity(GO:0004875)
0.9 1.8 GO:0019862 IgA binding(GO:0019862)
0.9 2.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.9 2.7 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.9 8.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.9 6.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.9 4.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.9 3.4 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.9 4.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.8 4.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.8 7.6 GO:0071723 lipopeptide binding(GO:0071723)
0.8 4.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.8 5.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.8 4.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.8 15.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.8 4.8 GO:0042608 T cell receptor binding(GO:0042608)
0.8 30.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.8 11.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.8 6.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.8 15.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.7 8.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.7 8.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 14.7 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.7 2.9 GO:0035939 microsatellite binding(GO:0035939)
0.7 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.7 4.4 GO:0004969 histamine receptor activity(GO:0004969)
0.7 10.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 7.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.7 20.3 GO:0017046 peptide hormone binding(GO:0017046)
0.7 5.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.7 2.9 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.7 2.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.7 6.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.7 191.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.7 10.5 GO:0008066 glutamate receptor activity(GO:0008066)
0.7 4.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.7 6.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.7 15.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.7 14.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.7 4.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.7 3.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.7 2.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.7 3.3 GO:0048039 ubiquinone binding(GO:0048039)
0.6 2.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.6 10.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6 1.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.6 1.9 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.6 0.6 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 3.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.6 3.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.6 3.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.6 2.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 2.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.6 1.2 GO:0042165 neurotransmitter binding(GO:0042165)
0.6 2.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.6 5.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 1.7 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.6 2.8 GO:0015197 peptide transporter activity(GO:0015197) peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) peptide transmembrane transporter activity(GO:1904680)
0.6 6.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.6 3.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.6 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.6 1.7 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.6 2.8 GO:0042287 MHC protein binding(GO:0042287)
0.5 1.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 1.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.5 5.8 GO:0019864 IgG binding(GO:0019864)
0.5 3.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.5 5.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5 13.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 71.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 6.8 GO:0045159 myosin II binding(GO:0045159)
0.5 5.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.5 5.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 2.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.5 19.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 2.6 GO:0017018 myosin phosphatase activity(GO:0017018)
0.5 8.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.5 1.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.5 6.0 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.5 7.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 61.6 GO:0005516 calmodulin binding(GO:0005516)
0.5 6.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.5 1.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.5 1.4 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.5 1.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 1.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.5 1.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.5 2.3 GO:0032052 bile acid binding(GO:0032052)
0.5 8.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 3.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5 2.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4 2.2 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.4 11.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 2.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.4 10.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.4 8.2 GO:0031489 myosin V binding(GO:0031489)
0.4 3.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 3.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.4 8.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.4 7.5 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.4 7.0 GO:0035586 purinergic receptor activity(GO:0035586)
0.4 4.7 GO:0019841 retinol binding(GO:0019841)
0.4 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 5.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.4 4.7 GO:0050700 CARD domain binding(GO:0050700)
0.4 16.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.4 1.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 3.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 8.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.4 5.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.4 3.5 GO:0035198 miRNA binding(GO:0035198)
0.3 4.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 17.0 GO:0005262 calcium channel activity(GO:0005262)
0.3 3.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 62.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.3 1.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.3 2.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 7.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 327.9 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 11.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.3 4.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 3.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 7.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 3.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 10.6 GO:0000149 SNARE binding(GO:0000149)
0.3 15.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.3 0.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.3 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 5.6 GO:0005501 retinoid binding(GO:0005501)
0.3 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 14.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 2.6 GO:0004707 MAP kinase activity(GO:0004707)
0.3 0.5 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.3 1.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 2.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 1.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 4.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 4.7 GO:0042605 peptide antigen binding(GO:0042605)
0.2 1.0 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.2 2.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 2.8 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.2 20.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 2.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.5 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.3 GO:0017040 ceramidase activity(GO:0017040)
0.2 41.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.2 0.6 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.2 0.8 GO:0070051 fibrinogen binding(GO:0070051)
0.2 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 1.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 0.5 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 4.6 GO:0005109 frizzled binding(GO:0005109)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 3.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 4.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.8 GO:0039552 RIG-I binding(GO:0039552)
0.1 4.4 GO:0030332 cyclin binding(GO:0030332)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.9 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 257.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
5.3 5.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
4.3 328.3 PID RHOA PATHWAY RhoA signaling pathway
3.5 41.6 PID TNF PATHWAY TNF receptor signaling pathway
3.0 65.4 PID CONE PATHWAY Visual signal transduction: Cones
2.9 70.3 PID S1P S1P4 PATHWAY S1P4 pathway
2.7 2.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
2.5 17.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
2.4 49.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
2.1 10.5 ST GAQ PATHWAY G alpha q Pathway
2.1 14.7 ST GA13 PATHWAY G alpha 13 Pathway
2.1 14.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
2.0 292.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
2.0 39.2 PID LPA4 PATHWAY LPA4-mediated signaling events
1.9 49.4 PID S1P S1P3 PATHWAY S1P3 pathway
1.9 20.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
1.9 7.5 ST STAT3 PATHWAY STAT3 Pathway
1.8 179.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
1.8 1.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.7 14.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.6 21.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.6 3.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.6 23.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
1.6 17.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
1.6 20.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.5 25.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
1.5 32.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.5 55.7 PID EPHA FWDPATHWAY EPHA forward signaling
1.4 15.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.4 5.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
1.4 15.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.4 45.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.3 16.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.2 6.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
1.2 4.9 ST G ALPHA S PATHWAY G alpha s Pathway
1.2 23.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
1.1 4.5 ST GA12 PATHWAY G alpha 12 Pathway
1.1 196.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.1 6.4 PID ALK1 PATHWAY ALK1 signaling events
1.1 11.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.1 21.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.1 56.5 PID ARF6 PATHWAY Arf6 signaling events
1.1 39.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.0 3.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
1.0 17.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.0 11.5 PID IL5 PATHWAY IL5-mediated signaling events
1.0 13.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
1.0 58.6 PID FGF PATHWAY FGF signaling pathway
1.0 57.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
1.0 5.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
1.0 13.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
1.0 48.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
1.0 38.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
1.0 42.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
1.0 34.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
1.0 5.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.9 20.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.9 19.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.9 2.8 ST ADRENERGIC Adrenergic Pathway
0.9 17.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.9 18.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.9 243.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.9 25.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.9 49.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.9 6.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.8 14.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.8 100.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.8 12.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.8 7.3 PID REELIN PATHWAY Reelin signaling pathway
0.8 49.8 PID LKB1 PATHWAY LKB1 signaling events
0.8 11.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.8 6.9 PID SHP2 PATHWAY SHP2 signaling
0.7 6.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.7 6.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.7 6.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.7 7.2 PID EPO PATHWAY EPO signaling pathway
0.7 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 14.4 PID BCR 5PATHWAY BCR signaling pathway
0.6 7.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.6 1.9 PID IL23 PATHWAY IL23-mediated signaling events
0.6 31.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.6 5.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.6 5.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.6 13.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.6 19.8 PID ATM PATHWAY ATM pathway
0.6 25.1 NABA COLLAGENS Genes encoding collagen proteins
0.5 8.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.5 14.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.5 3.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5 9.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 4.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.5 17.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.5 3.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 24.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.4 4.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.4 10.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.4 6.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.4 11.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 9.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 5.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.4 4.6 PID IL3 PATHWAY IL3-mediated signaling events
0.3 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 8.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 13.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 1.8 PID IL27 PATHWAY IL27-mediated signaling events
0.3 2.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 2.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 5.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 1.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 12.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 5.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 1.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 40.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 9.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 96.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
6.0 191.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
5.0 109.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
4.6 50.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
4.4 120.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
4.4 4.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
4.2 67.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
4.1 73.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
4.0 171.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
3.8 56.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
3.7 84.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
3.4 78.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
3.4 40.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
3.4 182.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
3.2 32.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
3.2 22.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
3.1 43.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
3.1 18.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
3.0 39.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
3.0 108.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
3.0 14.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
2.9 76.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
2.9 29.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
2.9 60.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
2.7 21.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
2.7 49.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
2.6 52.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
2.6 98.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
2.6 139.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
2.4 50.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
2.4 14.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.3 9.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
2.3 15.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
2.2 28.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
2.0 300.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
2.0 36.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.9 73.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.9 24.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.9 28.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.9 3.7 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
1.8 78.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
1.8 41.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
1.8 23.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.8 36.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
1.7 67.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
1.7 8.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
1.7 28.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
1.6 101.7 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
1.6 26.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
1.6 45.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.6 30.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.6 37.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.6 40.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
1.6 11.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
1.5 7.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
1.5 29.9 REACTOME DEFENSINS Genes involved in Defensins
1.5 19.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
1.4 28.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.4 65.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
1.4 14.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
1.4 32.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
1.4 26.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.4 148.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
1.4 32.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
1.3 17.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.3 13.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.3 11.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.3 108.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.3 23.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.3 22.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.3 8.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.2 36.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.2 56.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
1.2 19.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.2 80.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
1.2 29.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.2 67.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
1.2 19.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.2 14.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
1.2 10.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
1.2 10.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
1.2 67.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
1.1 115.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
1.1 34.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
1.1 6.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.1 6.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
1.1 6.6 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
1.1 35.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.1 7.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.1 14.8 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
1.0 16.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.0 47.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.0 165.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
1.0 8.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.0 13.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.0 5.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
1.0 5.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.9 20.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.9 17.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.9 10.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.8 12.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.8 46.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.8 12.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.8 21.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.8 4.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.8 16.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.8 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.8 12.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.8 3.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.8 11.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.7 26.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.7 3.7 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.7 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 18.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.7 15.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.7 9.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.7 17.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.7 6.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.7 4.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.7 4.8 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.7 42.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 21.4 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.6 7.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 15.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.6 8.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.6 11.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.5 4.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.5 6.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 15.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.5 38.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.5 4.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 167.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.5 8.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.4 10.3 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.4 4.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 2.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 1.9 REACTOME ADAPTIVE IMMUNE SYSTEM Genes involved in Adaptive Immune System
0.4 8.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 2.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3 6.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.3 7.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.3 1.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 6.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 8.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 8.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 12.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 2.7 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.2 5.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 5.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 10.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 5.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.5 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 4.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 2.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling