avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
INSM1 Links Ensembl NCBI GeneCards UniProt	ENSG00000173404.5	INSM1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
INSM1	hg38_v1_chr20_+_20368096_20368113	0.24	4.3e-04	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr9_+_135087652 Show fit	12.19	ENST00000371793.8 ENST00000539529.5 ENST00000392991.8	OLFM1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 1
chr17_-_44915486 Show fit	11.68	ENST00000638281.1 ENST00000588316.1 ENST00000588735.3 ENST00000639277.1 ENST00000253408.11 ENST00000435360.8 ENST00000586793.6 ENST00000588037.1 ENST00000592320.6	GFAP Links Ensembl NCBI GeneCards UniProt Show fit	glial fibrillary acidic protein
chr8_+_143734133 Show fit	9.48	ENST00000527139.7 ENST00000533004.5	IQANK1 Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif and ankyrin repeat containing 1
chr17_-_58529344 Show fit	9.36	ENST00000317268.7	SEPTIN4 Links Ensembl NCBI GeneCards UniProt Show fit	septin 4
chr17_-_58529303 Show fit	9.19	ENST00000580844.5	SEPTIN4 Links Ensembl NCBI GeneCards UniProt Show fit	septin 4
chr17_-_58529277 Show fit	9.12	ENST00000579371.5	SEPTIN4 Links Ensembl NCBI GeneCards UniProt Show fit	septin 4
chr20_+_46029165 Show fit	8.30	ENST00000616201.4 ENST00000616202.4 ENST00000616933.4 ENST00000626937.2	SLC12A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chr20_+_46029206 Show fit	8.15	ENST00000243964.7	SLC12A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chr5_-_11904417 Show fit	7.59	ENST00000304623.13	CTNND2 Links Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr10_-_102241502 Show fit	6.99	ENST00000370002.8	PITX3 Links Ensembl NCBI GeneCards UniProt Show fit	paired like homeodomain 3
chr15_+_43510945 Show fit	6.52	ENST00000382031.5	MAP1A Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 1A
chr3_+_35639589 Show fit	6.28	ENST00000428373.5	ARPP21 Links Ensembl NCBI GeneCards UniProt Show fit	cAMP regulated phosphoprotein 21
chr7_+_86644829 Show fit	6.23	ENST00000439827.1 ENST00000421579.1	GRM3 Links Ensembl NCBI GeneCards UniProt Show fit	glutamate metabotropic receptor 3
chr16_-_23557331 Show fit	6.01	ENST00000563232.1 ENST00000449606.7	EARS2 Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-tRNA synthetase 2, mitochondrial
chr13_-_36131286 Show fit	5.81	ENST00000255448.8 ENST00000379892.4	DCLK1 Links Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr16_-_19884828 Show fit	5.72	ENST00000300571.7 ENST00000570142.5 ENST00000562469.5	GPRC5B Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor class C group 5 member B
chr8_-_119673368 Show fit	5.65	ENST00000427067.6	ENPP2 Links Ensembl NCBI GeneCards UniProt Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr19_-_40414785 Show fit	5.51	ENST00000674005.2	PRX Links Ensembl NCBI GeneCards UniProt Show fit	periaxin
chr12_-_123972709 Show fit	4.94	ENST00000545891.5	CCDC92 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 92
chr10_+_114239245 Show fit	4.76	ENST00000392982.8	VWA2 Links Ensembl NCBI GeneCards UniProt Show fit	von Willebrand factor A domain containing 2
chr12_+_70366277 Show fit	4.66	ENST00000258111.5	KCNMB4 Links Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr8_-_102124253 Show fit	4.59	ENST00000524209.5 ENST00000517822.5 ENST00000523923.5 ENST00000521599.5 ENST00000521964.5 ENST00000311028.4 ENST00000518166.5	NCALD Links Ensembl NCBI GeneCards UniProt Show fit	neurocalcin delta
chr12_-_123972824 Show fit	4.47	ENST00000238156.8 ENST00000545037.1	CCDC92 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 92
chr22_+_20117424 Show fit	4.36	ENST00000402752.5	RANBP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr3_-_38029604 Show fit	4.18	ENST00000334661.5	PLCD1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase C delta 1
chr13_-_36131352 Show fit	4.07	ENST00000360631.8	DCLK1 Links Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr22_-_20117177 Show fit	4.06	ENST00000439169.2 ENST00000252136.12 ENST00000445045.1 ENST00000404751.7 ENST00000403707.7	TRMT2A Links Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 2 homolog A
chr7_+_154052373 Show fit	3.82	ENST00000377770.8 ENST00000406326.5	DPP6 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase like 6
chrX_+_52184874 Show fit	3.65	ENST00000599522.7 ENST00000471932.6	MAGED4 Links Ensembl NCBI GeneCards UniProt Show fit	MAGE family member D4
chr17_+_40062810 Show fit	3.52	ENST00000584985.5 ENST00000264637.8	THRA Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor alpha
chr9_+_35538619 Show fit	3.48	ENST00000455600.1	RUSC2 Links Ensembl NCBI GeneCards UniProt Show fit	RUN and SH3 domain containing 2
chr19_+_42313374 Show fit	3.37	ENST00000598766.1 ENST00000673187.1	TMEM145 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 145
chr9_-_120929160 Show fit	3.33	ENST00000540010.1	TRAF1 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 1
chr10_+_35127023 Show fit	3.32	ENST00000429130.7 ENST00000469949.6 ENST00000460270.5	CREM Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chrX_-_52069172 Show fit	3.28	ENST00000486010.1 ENST00000497164.5 ENST00000360134.10 ENST00000485287.5 ENST00000335504.9	MAGED4B Links Ensembl NCBI GeneCards UniProt Show fit	MAGE family member D4B
chr6_-_41895359 Show fit	3.26	ENST00000373006.5 ENST00000682992.1	USP49 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 49
chr1_+_220690354 Show fit	3.25	ENST00000294889.6	C1orf115 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 115
chr9_-_95507416 Show fit	3.09	ENST00000429896.6	PTCH1 Links Ensembl NCBI GeneCards UniProt Show fit	patched 1
chr2_+_24049673 Show fit	3.07	ENST00000380991.8	FKBP1B Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 1B
chr12_+_119667859 Show fit	3.02	ENST00000541640.5	PRKAB1 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit beta 1
chr4_-_36244438 Show fit	3.01	ENST00000303965.9	ARAP2 Links Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_+_52184904 Show fit	2.97	ENST00000375626.7 ENST00000467526.1	MAGED4 Links Ensembl NCBI GeneCards UniProt Show fit	MAGE family member D4
chr2_-_25252251 Show fit	2.97	ENST00000380746.8 ENST00000402667.1	DNMT3A Links Ensembl NCBI GeneCards UniProt Show fit	DNA methyltransferase 3 alpha
chr1_-_85259633 Show fit	2.90	ENST00000344356.5 ENST00000471115.6	C1orf52 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 52
chr1_+_10430720 Show fit	2.86	ENST00000602296.6	CENPS-CORT Links Ensembl NCBI GeneCards UniProt Show fit	CENPS-CORT readthrough
chr2_+_24049705 Show fit	2.86	ENST00000380986.9 ENST00000452109.1	FKBP1B Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 1B
chr11_-_8682619 Show fit	2.85	ENST00000646038.2	TRIM66 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 66
chr2_-_25252072 Show fit	2.85	ENST00000683760.1	DNMT3A Links Ensembl NCBI GeneCards UniProt Show fit	DNA methyltransferase 3 alpha
chr15_-_50765656 Show fit	2.85	ENST00000261854.10	SPPL2A Links Ensembl NCBI GeneCards UniProt Show fit	signal peptide peptidase like 2A
chr2_-_72825982 Show fit	2.80	ENST00000634650.1 ENST00000272427.11 ENST00000410104.1	EXOC6B Links Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 6B
chr18_-_36828939 Show fit	2.77	ENST00000593035.5 ENST00000383056.7 ENST00000588909.1 ENST00000590337.5 ENST00000334295.9	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr19_+_40778216 Show fit	2.72	ENST00000594800.5 ENST00000357052.8 ENST00000602173.5	RAB4B Links Ensembl NCBI GeneCards UniProt Show fit	RAB4B, member RAS oncogene family
chr22_-_27801712 Show fit	2.70	ENST00000302326.5	MN1 Links Ensembl NCBI GeneCards UniProt Show fit	MN1 proto-oncogene, transcriptional regulator
chr1_+_110210272 Show fit	2.66	ENST00000438661.3	KCNC4 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily C member 4
chr8_-_100559702 Show fit	2.65	ENST00000520311.5 ENST00000520552.5 ENST00000521345.1 ENST00000523000.5 ENST00000335659.7 ENST00000358990.3 ENST00000519597.5	ANKRD46 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 46
chr19_+_10086305 Show fit	2.63	ENST00000253110.16 ENST00000591813.5	SHFL Links Ensembl NCBI GeneCards UniProt Show fit	shiftless antiviral inhibitor of ribosomal frameshifting
chr10_+_35127295 Show fit	2.62	ENST00000489321.5 ENST00000427847.6 ENST00000374728.7 ENST00000345491.7 ENST00000487132.5	CREM Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr14_+_30874745 Show fit	2.55	ENST00000556908.5 ENST00000555881.5 ENST00000460581.6 ENST00000643575.1	COCH Links Ensembl NCBI GeneCards UniProt Show fit	cochlin
chr6_-_31158073 Show fit	2.52	ENST00000507751.5 ENST00000448162.6 ENST00000502557.5 ENST00000503420.5 ENST00000507892.1 ENST00000507226.1 ENST00000513222.1 ENST00000503934.5 ENST00000396263.6 ENST00000508683.5 ENST00000428174.1 ENST00000448141.6 ENST00000507829.5 ENST00000455279.6 ENST00000376266.9	CCHCR1 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil alpha-helical rod protein 1
chr9_-_137221323 Show fit	2.52	ENST00000391553.2 ENST00000392827.2	RNF208 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 208
chr12_-_52321395 Show fit	2.51	ENST00000293670.3	KRT83 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 83
chr12_+_119668109 Show fit	2.41	ENST00000229328.10 ENST00000630317.1	PRKAB1 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit beta 1
chr3_-_10708007 Show fit	2.33	ENST00000646379.1	ATP2B2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase plasma membrane Ca2+ transporting 2
chr15_-_65133780 Show fit	2.32	ENST00000204549.9	PDCD7 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 7
chr17_-_43833137 Show fit	2.31	ENST00000398389.9	MPP3 Links Ensembl NCBI GeneCards UniProt Show fit	membrane palmitoylated protein 3
chr1_-_154558650 Show fit	2.26	ENST00000292211.5	UBE2Q1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 Q1
chr14_+_30874541 Show fit	2.26	ENST00000396618.9 ENST00000644874.2 ENST00000555117.2 ENST00000475087.5	COCH Links Ensembl NCBI GeneCards UniProt Show fit	cochlin
chr14_+_30874497 Show fit	2.23	ENST00000216361.9	COCH Links Ensembl NCBI GeneCards UniProt Show fit	cochlin
chr17_-_65056659 Show fit	2.23	ENST00000439174.7	GNA13 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha 13
chr3_+_179322984 Show fit	2.23	ENST00000496856.6 ENST00000491818.5	ZNF639 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 639
chr15_+_88638947 Show fit	2.22	ENST00000559876.2	ISG20 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr12_+_7189675 Show fit	2.15	ENST00000675855.1 ENST00000434354.6 ENST00000544456.5 ENST00000545574.5 ENST00000420616.6	PEX5 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 5
chr14_-_93115812 Show fit	2.15	ENST00000553452.5	ITPK1 Links Ensembl NCBI GeneCards UniProt Show fit	inositol-tetrakisphosphate 1-kinase
chr9_+_128460559 Show fit	2.14	ENST00000372807.9 ENST00000444119.6	ODF2 Links Ensembl NCBI GeneCards UniProt Show fit	outer dense fiber of sperm tails 2
chr20_+_33490073 Show fit	2.13	ENST00000342704.11 ENST00000375279.6	CBFA2T2 Links Ensembl NCBI GeneCards UniProt Show fit	CBFA2/RUNX1 partner transcriptional co-repressor 2
chr12_+_53380141 Show fit	2.13	ENST00000551969.5 ENST00000327443.9	SP1 Links Ensembl NCBI GeneCards UniProt Show fit	Sp1 transcription factor
chr19_+_10086787 Show fit	2.11	ENST00000590378.5 ENST00000397881.7	SHFL Links Ensembl NCBI GeneCards UniProt Show fit	shiftless antiviral inhibitor of ribosomal frameshifting
chr21_-_34889735 Show fit	2.10	ENST00000399237.6	RUNX1 Links Ensembl NCBI GeneCards UniProt Show fit	RUNX family transcription factor 1
chr12_+_7189163 Show fit	2.02	ENST00000455147.6 ENST00000540398.5	PEX5 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 5
chr14_-_99272184 Show fit	2.01	ENST00000357195.8	BCL11B Links Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL11B
chr1_-_236281951 Show fit	2.00	ENST00000354619.10	ERO1B Links Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum oxidoreductase 1 beta
chr3_-_16513643 Show fit	2.00	ENST00000334133.9	RFTN1 Links Ensembl NCBI GeneCards UniProt Show fit	raftlin, lipid raft linker 1
chr1_+_168179030 Show fit	1.99	ENST00000367830.3	TIPRL Links Ensembl NCBI GeneCards UniProt Show fit	TOR signaling pathway regulator
chr7_-_91880672 Show fit	1.98	ENST00000456229.1 ENST00000442961.1 ENST00000406735.6 ENST00000419292.1 ENST00000351870.8	MTERF1 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial transcription termination factor 1
chr17_-_4987354 Show fit	1.97	ENST00000361571.9	CAMTA2 Links Ensembl NCBI GeneCards UniProt Show fit	calmodulin binding transcription activator 2
chr17_-_48590231 Show fit	1.97	ENST00000476342.1 ENST00000460160.5 ENST00000498678.6 ENST00000472863.5	HOXB3 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox B3
chr9_-_124771238 Show fit	1.96	ENST00000344523.8 ENST00000373584.7	NR6A1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 6 group A member 1
chrX_-_153794356 Show fit	1.96	ENST00000427365.6 ENST00000444450.5 ENST00000217901.10 ENST00000370093.5	IDH3G Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chrX_-_153794494 Show fit	1.90	ENST00000370092.7 ENST00000619865.4	IDH3G Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chr17_-_60392113 Show fit	1.84	ENST00000300896.9 ENST00000589335.5	USP32 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 32
chr17_+_39637125 Show fit	1.83	ENST00000544210.6 ENST00000581894.5 ENST00000394250.8 ENST00000336308.10 ENST00000579479.5 ENST00000577248.5 ENST00000580611.5	STARD3 Links Ensembl NCBI GeneCards UniProt Show fit	StAR related lipid transfer domain containing 3
chr14_+_85530127 Show fit	1.82	ENST00000330753.6	FLRT2 Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin leucine rich transmembrane protein 2
chr17_+_29043124 Show fit	1.81	ENST00000323372.9	PIPOX Links Ensembl NCBI GeneCards UniProt Show fit	pipecolic acid and sarcosine oxidase
chr19_-_56121223 Show fit	1.80	ENST00000587279.1 ENST00000610935.2	ZNF787 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 787
chr12_+_7189845 Show fit	1.80	ENST00000412720.6 ENST00000396637.7	PEX5 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 5
chr12_+_7189582 Show fit	1.79	ENST00000266563.9 ENST00000543974.5	PEX5 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 5
chr15_+_26971149 Show fit	1.77	ENST00000615808.5	GABRG3 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma3
chr3_+_71753834 Show fit	1.76	ENST00000304411.3	GPR27 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 27
chr22_-_36507022 Show fit	1.73	ENST00000216187.10 ENST00000397224.9 ENST00000423980.1	FOXRED2 Links Ensembl NCBI GeneCards UniProt Show fit	FAD dependent oxidoreductase domain containing 2
chr19_-_38849923 Show fit	1.72	ENST00000601813.1 ENST00000221419.10	HNRNPL Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein L
chr14_-_75126964 Show fit	1.70	ENST00000678037.1 ENST00000553823.6 ENST00000678531.1 ENST00000238616.10	NEK9 Links Ensembl NCBI GeneCards UniProt Show fit	NIMA related kinase 9
chr9_-_37034261 Show fit	1.70	ENST00000358127.9 ENST00000377852.7 ENST00000523241.6	PAX5 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 5
chr3_-_15332526 Show fit	1.69	ENST00000383791.8	SH3BP5 Links Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding protein 5
chr17_+_60677822 Show fit	1.63	ENST00000407086.8 ENST00000589222.5 ENST00000626960.2 ENST00000390652.9	BCAS3 Links Ensembl NCBI GeneCards UniProt Show fit	BCAS3 microtubule associated cell migration factor
chr22_+_46762617 Show fit	1.63	ENST00000380995.5 ENST00000337137.9 ENST00000407381.7	TBC1D22A Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 22A
chr11_-_66677748 Show fit	1.62	ENST00000525754.5 ENST00000531969.5 ENST00000524637.1 ENST00000531036.2 ENST00000310046.9	RBM4B Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 4B
chr18_+_48539112 Show fit	1.62	ENST00000382998.8	CTIF Links Ensembl NCBI GeneCards UniProt Show fit	cap binding complex dependent translation initiation factor
chr10_+_35126791 Show fit	1.58	ENST00000474362.5 ENST00000374721.7	CREM Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr14_+_85530163 Show fit	1.58	ENST00000554746.1	FLRT2 Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin leucine rich transmembrane protein 2
chr14_-_99271485 Show fit	1.57	ENST00000345514.2 ENST00000443726.2	BCL11B Links Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL11B
chr12_-_56189459 Show fit	1.45	ENST00000550164.6	SMARCC2 Links Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
chr2_-_72147819 Show fit	1.44	ENST00000001146.7 ENST00000546307.5 ENST00000474509.1	CYP26B1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 26 subfamily B member 1
chr11_+_118436464 Show fit	1.38	ENST00000389506.10 ENST00000534358.8 ENST00000531904.6 ENST00000649699.1	KMT2A Links Ensembl NCBI GeneCards UniProt Show fit	lysine methyltransferase 2A
chr2_-_241150264 Show fit	1.34	ENST00000405260.5	PASK Links Ensembl NCBI GeneCards UniProt Show fit	PAS domain containing serine/threonine kinase
chr10_+_74825445 Show fit	1.33	ENST00000649006.1 ENST00000649463.1 ENST00000372725.6	KAT6B Links Ensembl NCBI GeneCards UniProt Show fit	lysine acetyltransferase 6B
chr18_-_36828771 Show fit	1.33	ENST00000589049.5 ENST00000587129.5 ENST00000590842.5	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr5_-_176537361 Show fit	1.31	ENST00000274811.9	RNF44 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 44
chr12_+_48978453 Show fit	1.27	ENST00000613114.4	WNT1 Links Ensembl NCBI GeneCards UniProt Show fit	Wnt family member 1
chr22_+_37051787 Show fit	1.27	ENST00000456470.1	KCTD17 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 17
chr13_+_46553157 Show fit	1.27	ENST00000311191.10 ENST00000389797.8 ENST00000389798.7	LRCH1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and calponin homology domain containing 1
chr15_+_88639009 Show fit	1.25	ENST00000306072.10	ISG20 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr10_-_101843920 Show fit	1.23	ENST00000358038.7	KCNIP2 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel interacting protein 2
chr22_+_37051731 Show fit	1.23	ENST00000610767.4 ENST00000402077.7 ENST00000403888.7	KCTD17 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 17
chr4_-_163332589 Show fit	1.21	ENST00000296533.3 ENST00000509586.5 ENST00000504391.5 ENST00000512819.1	NPY1R Links Ensembl NCBI GeneCards UniProt Show fit	neuropeptide Y receptor Y1
chr14_-_93115869 Show fit	1.20	ENST00000556603.6 ENST00000354313.7 ENST00000267615.11	ITPK1 Links Ensembl NCBI GeneCards UniProt Show fit	inositol-tetrakisphosphate 1-kinase
chr14_+_76761453 Show fit	1.18	ENST00000167106.9	VASH1 Links Ensembl NCBI GeneCards UniProt Show fit	vasohibin 1
chr11_-_74170792 Show fit	1.13	ENST00000680231.1 ENST00000681143.1 ENST00000679906.1 ENST00000681310.1 ENST00000414160.7 ENST00000538361.2	C2CD3 Links Ensembl NCBI GeneCards UniProt Show fit	C2 domain containing 3 centriole elongation regulator
chr16_+_30664334 Show fit	1.11	ENST00000287468.5	FBRS Links Ensembl NCBI GeneCards UniProt Show fit	fibrosin
chr2_+_98444835 Show fit	1.10	ENST00000409016.8 ENST00000409463.5 ENST00000074304.9 ENST00000409851.8 ENST00000409540.7	INPP4A Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type I A
chr4_+_55948871 Show fit	1.10	ENST00000422247.6 ENST00000257287.5	CEP135 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 135
chr14_+_64465491 Show fit	1.07	ENST00000394718.4	AKAP5 Links Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 5
chr18_+_48539017 Show fit	1.07	ENST00000256413.8	CTIF Links Ensembl NCBI GeneCards UniProt Show fit	cap binding complex dependent translation initiation factor
chr4_+_625555 Show fit	1.05	ENST00000496514.6 ENST00000255622.10	PDE6B Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 6B
chr8_-_144326842 Show fit	1.02	ENST00000528718.6	DGAT1 Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol O-acyltransferase 1
chr10_-_101843777 Show fit	1.00	ENST00000356640.7	KCNIP2 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel interacting protein 2
chr22_+_46762677 Show fit	0.97	ENST00000355704.7	TBC1D22A Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 22A
chr3_-_46693664 Show fit	0.96	ENST00000318962.9	ALS2CL Links Ensembl NCBI GeneCards UniProt Show fit	ALS2 C-terminal like
chr17_-_8965674 Show fit	0.95	ENST00000447110.6 ENST00000611902.4 ENST00000616147.4 ENST00000623421.3	PIK3R5 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase regulatory subunit 5
chr1_-_53889766 Show fit	0.95	ENST00000371399.5 ENST00000072644.7	YIPF1 Links Ensembl NCBI GeneCards UniProt Show fit	Yip1 domain family member 1
chr11_-_74170975 Show fit	0.92	ENST00000539061.6 ENST00000680645.1 ENST00000334126.12 ENST00000680718.1	C2CD3 Links Ensembl NCBI GeneCards UniProt Show fit	C2 domain containing 3 centriole elongation regulator
chr19_+_49474208 Show fit	0.92	ENST00000597551.6 ENST00000596435.5 ENST00000204637.6 ENST00000600429.5	FLT3LG Links Ensembl NCBI GeneCards UniProt Show fit	fms related receptor tyrosine kinase 3 ligand
chr9_-_124771304 Show fit	0.90	ENST00000416460.6 ENST00000487099.7	NR6A1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 6 group A member 1
chr18_-_36828730 Show fit	0.87	ENST00000587382.5	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr9_+_37650947 Show fit	0.86	ENST00000377765.8	FRMPD1 Links Ensembl NCBI GeneCards UniProt Show fit	FERM and PDZ domain containing 1
chr1_-_154859841 Show fit	0.85	ENST00000361147.8	KCNN3 Links Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily N member 3
chr17_+_20009320 Show fit	0.82	ENST00000679049.1 ENST00000472876.5 ENST00000583528.6 ENST00000680019.1 ENST00000681593.1 ENST00000395527.8 ENST00000583482.7 ENST00000679255.1 ENST00000681202.1 ENST00000677914.1	SPECC1 Links Ensembl NCBI GeneCards UniProt Show fit	sperm antigen with calponin homology and coiled-coil domains 1
chr17_-_39225936 Show fit	0.82	ENST00000333461.6	STAC2 Links Ensembl NCBI GeneCards UniProt Show fit	SH3 and cysteine rich domain 2
chr2_+_241150418 Show fit	0.82	ENST00000404405.7 ENST00000439916.5 ENST00000234038.11 ENST00000406106.7 ENST00000401987.5	PPP1R7 Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 7
chr8_-_144326908 Show fit	0.80	ENST00000332324.5	DGAT1 Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol O-acyltransferase 1
chr14_+_94026314 Show fit	0.78	ENST00000203664.10 ENST00000553723.1	OTUB2 Links Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase, ubiquitin aldehyde binding 2
chr1_-_160070150 Show fit	0.75	ENST00000644903.1	KCNJ10 Links Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 10
chr14_+_102777433 Show fit	0.73	ENST00000392745.8	TRAF3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 3
chr17_-_64497025 Show fit	0.72	ENST00000539111.7	POLG2 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase gamma 2, accessory subunit
chr5_-_179345423 Show fit	0.68	ENST00000518335.3 ENST00000274609.5 ENST00000251582.12	ADAMTS2 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 2
chr1_+_209827964 Show fit	0.67	ENST00000491415.7	UTP25 Links Ensembl NCBI GeneCards UniProt Show fit	UTP25 small subunit processor component
chrX_-_72305892 Show fit	0.63	ENST00000450875.5 ENST00000417400.1 ENST00000431381.5 ENST00000445983.5 ENST00000651998.1	CITED1 Links Ensembl NCBI GeneCards UniProt Show fit	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr13_-_31161890 Show fit	0.63	ENST00000320027.10	HSPH1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family H (Hsp110) member 1
chr1_-_160070102 Show fit	0.63	ENST00000638728.1 ENST00000637644.1	KCNJ10 Links Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 10
chr10_+_89301932 Show fit	0.62	ENST00000371826.4 ENST00000679755.1	IFIT2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 2
chr17_-_44385332 Show fit	0.62	ENST00000648408.1	ITGA2B Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 2b
chr18_-_36067524 Show fit	0.61	ENST00000590898.5 ENST00000357384.8 ENST00000399022.9 ENST00000588737.5	RPRD1A Links Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 1A
chr12_+_53380639 Show fit	0.61	ENST00000426431.2	SP1 Links Ensembl NCBI GeneCards UniProt Show fit	Sp1 transcription factor
chr3_+_50155305 Show fit	0.61	ENST00000002829.8 ENST00000426511.5	SEMA3F Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3F
chr1_-_205357033 Show fit	0.59	ENST00000367156.7 ENST00000606887.5 ENST00000539253.5 ENST00000607173.5	KLHDC8A Links Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 8A
chr17_+_48107549 Show fit	0.57	ENST00000580219.5 ENST00000452859.6 ENST00000393405.6	SNX11 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 11
chr8_+_42271289 Show fit	0.55	ENST00000520810.6 ENST00000520835.7	IKBKB Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of nuclear factor kappa B kinase subunit beta
chr1_+_32817645 Show fit	0.52	ENST00000526230.1 ENST00000373475.10 ENST00000531256.1 ENST00000482212.1	S100PBP Links Ensembl NCBI GeneCards UniProt Show fit	S100P binding protein
chr14_+_65412949 Show fit	0.52	ENST00000674118.1 ENST00000553924.5 ENST00000358307.6 ENST00000557338.5 ENST00000554610.1	FUT8 Links Ensembl NCBI GeneCards UniProt Show fit	fucosyltransferase 8
chr1_+_2467437 Show fit	0.51	ENST00000449969.5	PLCH2 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase C eta 2
chr19_+_14031746 Show fit	0.51	ENST00000263379.4	IL27RA Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 27 receptor subunit alpha
chr19_+_49474561 Show fit	0.45	ENST00000594009.5 ENST00000595510.1 ENST00000595815.1	FLT3LG Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000273189.1 Links Ensembl NCBI GeneCards UniProt Show fit	fms related receptor tyrosine kinase 3 ligand novel transcript
chr9_+_113501359 Show fit	0.43	ENST00000343817.9 ENST00000394646.7	RGS3 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 3
chr12_-_79934920 Show fit	0.43	ENST00000550107.5	PPP1R12A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12A
chr12_-_51026345 Show fit	0.41	ENST00000547732.5 ENST00000644495.1 ENST00000262052.9 ENST00000546488.5 ENST00000550714.5 ENST00000548193.5 ENST00000547579.5 ENST00000546743.5	SLC11A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 member 2
chr19_-_45973986 Show fit	0.40	ENST00000676183.1	NOVA2 Links Ensembl NCBI GeneCards UniProt Show fit	NOVA alternative splicing regulator 2
chr11_+_66857056 Show fit	0.40	ENST00000309602.5 ENST00000393952.3	LRFN4 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat and fibronectin type III domain containing 4
chr3_+_50155024 Show fit	0.34	ENST00000414301.5 ENST00000450338.5 ENST00000413852.5	SEMA3F Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3F
chr8_-_141001192 Show fit	0.33	ENST00000521059.5	PTK2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr8_-_141001217 Show fit	0.32	ENST00000522684.5 ENST00000524357.5 ENST00000521332.5 ENST00000524040.5 ENST00000519881.5 ENST00000520045.5	PTK2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr3_+_10816201 Show fit	0.31	ENST00000454147.1 ENST00000254488.7	SLC6A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 11
chr3_-_15859771 Show fit	0.31	ENST00000399451.6	ANKRD28 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 28
chr13_-_31161927 Show fit	0.30	ENST00000380405.7	HSPH1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family H (Hsp110) member 1
chr6_-_33418125 Show fit	0.28	ENST00000492510.1 ENST00000374500.10	CUTA Links Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr2_+_219442023 Show fit	0.27	ENST00000431523.5 ENST00000396698.5	SPEG Links Ensembl NCBI GeneCards UniProt Show fit	striated muscle enriched protein kinase
chrX_+_16786421 Show fit	0.27	ENST00000398155.4 ENST00000380122.10	TXLNG Links Ensembl NCBI GeneCards UniProt Show fit	taxilin gamma
chr18_-_36829154 Show fit	0.25	ENST00000614939.4 ENST00000610723.4	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr19_+_48469354 Show fit	0.25	ENST00000452733.7 ENST00000641098.1	CYTH2 Links Ensembl NCBI GeneCards UniProt Show fit	cytohesin 2
chrX_+_153642473 Show fit	0.24	ENST00000370167.8	DUSP9 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 9
chr9_+_88388356 Show fit	0.24	ENST00000375859.4	SPIN1 Links Ensembl NCBI GeneCards UniProt Show fit	spindlin 1
chr10_-_50623897 Show fit	0.22	ENST00000361781.7 ENST00000429490.5 ENST00000619438.4	SGMS1 Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin synthase 1
chr17_-_75393741 Show fit	0.21	ENST00000578961.5 ENST00000392564.5	GRB2 Links Ensembl NCBI GeneCards UniProt Show fit	growth factor receptor bound protein 2
chrX_+_70455093 Show fit	0.19	ENST00000542398.1	DLG3 Links Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 3
chr12_-_51026325 Show fit	0.18	ENST00000547198.5 ENST00000643884.1	SLC11A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 member 2
chr12_+_51591216 Show fit	0.12	ENST00000668547.1 ENST00000354534.11 ENST00000627620.5 ENST00000545061.5	SCN8A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 8
chr12_+_2890907 Show fit	0.12	ENST00000397132.6	TULP3 Links Ensembl NCBI GeneCards UniProt Show fit	TUB like protein 3
chr14_+_65412717 Show fit	0.08	ENST00000673929.1	FUT8 Links Ensembl NCBI GeneCards UniProt Show fit	fucosyltransferase 8
chr16_-_10942443 Show fit	0.07	ENST00000570440.2 ENST00000331808.5	DEXI Links Ensembl NCBI GeneCards UniProt Show fit	Dexi homolog
chr3_-_48685835 Show fit	0.05	ENST00000439518.5 ENST00000416649.6 ENST00000294129.7	NCKIPSD Links Ensembl NCBI GeneCards UniProt Show fit	NCK interacting protein with SH3 domain
chr8_-_141001145 Show fit	0.04	ENST00000340930.7 ENST00000520828.5 ENST00000524257.5 ENST00000523679.1	PTK2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr16_+_23557714 Show fit	0.03	ENST00000567212.5 ENST00000567264.1 ENST00000395878.8	UBFD1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin family domain containing 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	16.4	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
2.3	7.0	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
1.6	7.8	GO:1901091	regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
1.4	12.2	GO:0003190	atrioventricular valve formation(GO:0003190)
1.2	3.6	GO:0097534	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.2	3.5	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.0	5.1	GO:0021997	neural plate axis specification(GO:0021997)
1.0	5.8	GO:0090116	C-5 methylation of cytosine(GO:0090116)
1.0	6.7	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.9	2.7	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.7	4.8	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.6	5.9	GO:0061179	positive regulation of axon regeneration(GO:0048680) negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.6	2.9	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.6	11.7	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.6	3.9	GO:0006102	isocitrate metabolic process(GO:0006102)
0.5	3.3	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.5	2.7	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5	2.0	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.5	1.4	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.5	1.4	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038)
0.5	1.8	GO:0019474	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4	2.0	GO:0030070	insulin processing(GO:0030070)
0.4	1.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.4	5.4	GO:0035878	nail development(GO:0035878)
0.4	5.7	GO:0034638	phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.4	6.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4	1.8	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3	1.4	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.3	5.7	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.3	6.7	GO:0005513	detection of calcium ion(GO:0005513)
0.3	2.6	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.3	1.4	GO:0051935	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3	1.8	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.3	0.8	GO:0061054	dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184)
0.2	2.0	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.2	2.2	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.2	1.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.2	2.0	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.2	0.6	GO:0036071	N-glycan fucosylation(GO:0036071)
0.2	2.3	GO:0070459	prolactin secretion(GO:0070459)
0.2	9.6	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.2	3.3	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.2	4.2	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.2	1.8	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.2	0.6	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1	0.7	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	0.6	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.9	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	0.9	GO:1903751	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1	3.6	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.1	3.8	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	7.5	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.6	GO:0071105	response to interleukin-11(GO:0071105)
0.1	0.5	GO:0015692	lead ion transport(GO:0015692)
0.1	1.6	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1	2.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.1	1.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.4	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1	7.6	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.1	0.8	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.1	4.1	GO:0001510	RNA methylation(GO:0001510)
0.1	1.6	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.1	1.6	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	1.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	1.4	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.7	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.1	2.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	1.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	1.7	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	2.0	GO:0014887	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	2.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	9.4	GO:0007605	sensory perception of sound(GO:0007605)
0.0	0.5	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	2.6	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.6	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	3.3	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	2.5	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	2.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	3.8	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	2.5	GO:0006611	protein export from nucleus(GO:0006611)
0.0	5.6	GO:0007272	ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0	4.6	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.0	0.9	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	2.7	GO:0046323	glucose import(GO:0046323)
0.0	3.5	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	1.7	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	0.8	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.7	GO:0030199	collagen fibril organization(GO:0030199)
0.0	1.2	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	2.9	GO:0030518	intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0	0.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	1.0	GO:0007032	endosome organization(GO:0007032)
0.0	0.6	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	1.5	GO:0007286	spermatid development(GO:0007286)
0.0	1.2	GO:0070268	cornification(GO:0070268)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	15.3	GO:0044295	axonal growth cone(GO:0044295)
0.6	2.9	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.4	5.8	GO:0001741	XY body(GO:0001741)
0.3	0.9	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3	4.6	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3	5.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	16.6	GO:0043198	dendritic shaft(GO:0043198)
0.2	2.7	GO:0032593	insulin-responsive compartment(GO:0032593)
0.2	2.1	GO:0001520	outer dense fiber(GO:0001520)
0.2	2.8	GO:0000145	exocyst(GO:0000145)
0.1	1.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	15.1	GO:0005814	centriole(GO:0005814)
0.1	0.5	GO:0070826	paraferritin complex(GO:0070826)
0.1	2.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.1	12.9	GO:0005882	intermediate filament(GO:0005882)
0.1	7.8	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	5.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	1.8	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	13.1	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	1.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	7.6	GO:0043204	perikaryon(GO:0043204)
0.1	2.9	GO:0016235	aggresome(GO:0016235)
0.1	3.5	GO:0015030	Cajal body(GO:0015030)
0.1	2.7	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	1.4	GO:0071564	SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.0	1.8	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	1.4	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	1.1	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	12.9	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	6.5	GO:0005875	microtubule associated complex(GO:0005875)
0.0	1.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.9	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	1.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	1.8	GO:0034707	chloride channel complex(GO:0034707)
0.0	2.3	GO:0030175	filopodium(GO:0030175)
0.0	0.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	5.2	GO:0005874	microtubule(GO:0005874)
0.0	1.8	GO:0035579	specific granule membrane(GO:0035579)
0.0	1.7	GO:0005604	basement membrane(GO:0005604)
0.0	4.1	GO:0043025	neuronal cell body(GO:0043025)
0.0	3.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.6	GO:0031526	brush border membrane(GO:0031526)
0.0	1.7	GO:0001650	fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.2	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
1.6	7.8	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
1.4	5.7	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.2	16.4	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.2	3.5	GO:0008859	exoribonuclease II activity(GO:0008859)
1.1	3.3	GO:0052726	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
1.0	5.9	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.0	5.8	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.0	3.9	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.8	3.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.6	1.8	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.5	1.6	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.5	7.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	1.4	GO:0045322	unmethylated CpG binding(GO:0045322)
0.4	2.9	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4	1.2	GO:0001601	peptide YY receptor activity(GO:0001601)
0.4	5.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.4	1.8	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3	6.7	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.3	2.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	4.1	GO:0031996	thioesterase binding(GO:0031996)
0.2	0.6	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2	4.3	GO:0045499	chemorepellent activity(GO:0045499)
0.2	2.9	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.6	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	4.2	GO:0032794	GTPase activating protein binding(GO:0032794) phosphatidic acid binding(GO:0070300)
0.2	1.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	5.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	3.8	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	5.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	1.7	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.1	2.0	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1	2.5	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.6	GO:0070051	fibrinogen binding(GO:0070051)
0.1	2.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.1	1.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.5	GO:0015086	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1	0.9	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	2.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.8	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	3.0	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	0.8	GO:0016015	morphogen activity(GO:0016015)
0.1	1.8	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	2.7	GO:0071837	HMG box domain binding(GO:0071837)
0.1	3.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	0.2	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	4.1	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.1	0.5	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	5.1	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1	10.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	6.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	2.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	5.6	GO:0005518	collagen binding(GO:0005518)
0.0	1.8	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.6	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.3	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	1.4	GO:0001972	retinoic acid binding(GO:0001972)
0.0	9.0	GO:0005057	receptor signaling protein activity(GO:0005057)
0.0	2.9	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.7	GO:0008432	JUN kinase binding(GO:0008432)
0.0	2.2	GO:0043621	protein self-association(GO:0043621)
0.0	1.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	2.7	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	4.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	1.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	1.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	1.3	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	1.7	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	3.8	GO:0005516	calmodulin binding(GO:0005516)
0.0	1.7	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	7.5	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	4.3	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	2.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	3.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.7	PID BCR 5PATHWAY	BCR signaling pathway
0.1	11.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	3.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.9	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	3.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	2.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	1.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	6.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	5.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	11.6	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	3.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	4.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	5.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	2.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	16.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	1.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	2.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	1.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	0.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	5.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.7	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	2.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	4.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	1.8	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	3.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.4	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	2.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	3.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation