avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
IRF3 Links Ensembl NCBI GeneCards UniProt	ENSG00000126456.16	IRF3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IRF3	hg38_v1_chr19_-_49665603_49665617	0.47	1.7e-13	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr6_+_32854179 Show fit	20.46	ENST00000374859.3	PSMB9 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr1_+_1013485 Show fit	19.00	ENST00000649529.1	ISG15 Links Ensembl NCBI GeneCards UniProt Show fit	ISG15 ubiquitin like modifier
chr14_+_24136152 Show fit	14.42	ENST00000559123.5 ENST00000206451.11 ENST00000382708.7 ENST00000561435.5	PSME1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 1
chr15_+_88639009 Show fit	14.40	ENST00000306072.10	ISG20 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr12_+_112978386 Show fit	13.69	ENST00000342315.8	OAS2 Links Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 2
chr19_-_17405554 Show fit	13.19	ENST00000252593.7	BST2 Links Ensembl NCBI GeneCards UniProt Show fit	bone marrow stromal cell antigen 2
chr8_-_66613208 Show fit	12.63	ENST00000522677.8	MYBL1 Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene like 1
chr1_+_78649818 Show fit	11.80	ENST00000370747.9 ENST00000438486.1	IFI44 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein 44
chr21_+_41420515 Show fit	11.74	ENST00000398600.6 ENST00000679626.1	MX1 Links Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr19_+_18173804 Show fit	10.63	ENST00000407280.4	IFI30 Links Ensembl NCBI GeneCards UniProt Show fit	IFI30 lysosomal thiol reductase
chr6_-_32853618 Show fit	10.47	ENST00000354258.5	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr17_-_35880350 Show fit	10.25	ENST00000605140.6 ENST00000651122.1 ENST00000603197.6	CCL5 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 5
chr6_-_32853813 Show fit	10.15	ENST00000643049.2	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr7_-_140062841 Show fit	10.06	ENST00000263549.8	PARP12 Links Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 12
chr2_-_230219902 Show fit	10.05	ENST00000409815.6	SP110 Links Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr11_-_615570 Show fit	9.55	ENST00000649187.1 ENST00000647801.1 ENST00000397566.5 ENST00000397570.5	IRF7 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr11_-_57567617 Show fit	9.41	ENST00000287156.9	UBE2L6 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L6
chr11_+_63536801 Show fit	9.23	ENST00000255688.8 ENST00000439013.6	PLAAT4 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase A and acyltransferase 4
chr10_+_89327989 Show fit	9.01	ENST00000679923.1 ENST00000680085.1 ENST00000371818.9 ENST00000680779.1	IFIT3 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 3
chr10_+_89327977 Show fit	8.93	ENST00000681277.1	IFIT3 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 3
chr7_-_139109337 Show fit	8.85	ENST00000464606.5	ZC3HAV1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing, antiviral 1
chr2_-_230219944 Show fit	8.85	ENST00000455674.2 ENST00000392048.7 ENST00000258381.11 ENST00000358662.9 ENST00000258382.10	SP110 Links Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr11_-_615921 Show fit	8.69	ENST00000348655.11 ENST00000525445.6 ENST00000330243.9	IRF7 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr2_-_162318129 Show fit	8.56	ENST00000679938.1	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr12_+_112978562 Show fit	8.00	ENST00000680122.1	OAS2 Links Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 2
chr2_+_201116793 Show fit	7.96	ENST00000441224.5	CFLAR Links Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr2_-_162318475 Show fit	7.73	ENST00000648433.1	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr9_-_92325577 Show fit	7.67	ENST00000358855.8 ENST00000421075.6 ENST00000536624.5	NOL8 Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 8
chr2_-_162318613 Show fit	7.62	ENST00000649979.2 ENST00000421365.2	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr9_-_92325322 Show fit	7.59	ENST00000542613.5 ENST00000542053.5 ENST00000442668.7 ENST00000545558.5 ENST00000432670.6 ENST00000433029.6 ENST00000411621.6	NOL8 Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 8
chr2_+_126656128 Show fit	7.48	ENST00000259254.9 ENST00000409836.3 ENST00000356887.12	GYPC Links Ensembl NCBI GeneCards UniProt Show fit	glycophorin C (Gerbich blood group)
chr6_-_132763424 Show fit	7.22	ENST00000532012.1 ENST00000525270.5 ENST00000530536.5 ENST00000524919.5	VNN2 Links Ensembl NCBI GeneCards UniProt Show fit	vanin 2
chr6_+_26365215 Show fit	7.08	ENST00000527422.5 ENST00000356386.6 ENST00000396948.5	BTN3A2 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A2
chr6_+_26365176 Show fit	6.91	ENST00000377708.7	BTN3A2 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A2
chrX_-_110318062 Show fit	6.71	ENST00000372059.6 ENST00000262844.10	AMMECR1 Links Ensembl NCBI GeneCards UniProt Show fit	AMMECR nuclear protein 1
chr6_+_26440472 Show fit	6.49	ENST00000494393.5 ENST00000482451.5 ENST00000471353.5 ENST00000361232.7 ENST00000487627.5 ENST00000496719.1 ENST00000244519.7 ENST00000490254.5 ENST00000487272.1	BTN3A3 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A3
chr6_-_41071825 Show fit	6.26	ENST00000468811.5	OARD1 Links Ensembl NCBI GeneCards UniProt Show fit	O-acyl-ADP-ribose deacylase 1
chr10_+_89332484 Show fit	6.05	ENST00000371811.4 ENST00000680037.1 ENST00000679583.1 ENST00000679897.1	IFIT3 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 3
chr19_-_39846329 Show fit	5.96	ENST00000599134.1 ENST00000597634.5 ENST00000598417.5 ENST00000601274.5 ENST00000594309.5 ENST00000221801.8	FBL Links Ensembl NCBI GeneCards UniProt Show fit	fibrillarin
chr6_+_26365159 Show fit	5.84	ENST00000532865.5 ENST00000396934.7 ENST00000508906.6 ENST00000530653.5 ENST00000527417.5	BTN3A2 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A2
chr12_+_112978504 Show fit	5.65	ENST00000392583.7	OAS2 Links Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 2
chr14_-_24146596 Show fit	5.60	ENST00000560410.5 ENST00000216802.10 ENST00000615264.4 ENST00000630027.1	PSME2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 2
chr8_-_108443409 Show fit	5.48	ENST00000678023.1 ENST00000679198.1 ENST00000678881.1 ENST00000677084.1 ENST00000676663.1 ENST00000677614.1 ENST00000677040.1 ENST00000676487.1 ENST00000677409.1 ENST00000678797.1 ENST00000678334.1	EIF3E Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit E
chr7_-_139109702 Show fit	5.47	ENST00000471652.1 ENST00000242351.10	ZC3HAV1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing, antiviral 1
chr8_+_26293112 Show fit	5.40	ENST00000523925.5 ENST00000315985.7	PPP2R2A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Balpha
chr7_-_93117956 Show fit	5.40	ENST00000446617.1 ENST00000379958.3 ENST00000620985.4	SAMD9 Links Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 9
chr17_+_42289213 Show fit	5.36	ENST00000677301.1	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr5_-_95822711 Show fit	5.04	ENST00000512469.2 ENST00000379979.8 ENST00000505427.1 ENST00000508780.5 ENST00000237858.11	GLRX Links Ensembl NCBI GeneCards UniProt Show fit	glutaredoxin
chr14_+_73058521 Show fit	4.99	ENST00000527432.5 ENST00000531500.5 ENST00000261973.12 ENST00000525321.5 ENST00000526754.5	RBM25 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 25
chr6_+_26402237 Show fit	4.92	ENST00000476549.6 ENST00000450085.6 ENST00000425234.6 ENST00000427334.5 ENST00000506698.1 ENST00000289361.11	BTN3A1 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A1
chr22_+_36253071 Show fit	4.79	ENST00000422706.5 ENST00000426053.5 ENST00000319136.8	APOL1 Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L1
chr1_+_149475045 Show fit	4.76	ENST00000651566.2	NBPF19 Links Ensembl NCBI GeneCards UniProt Show fit	NBPF member 19
chr9_-_32526185 Show fit	4.46	ENST00000379883.3 ENST00000379868.6 ENST00000679859.1	DDX58 Links Ensembl NCBI GeneCards UniProt Show fit	DExD/H-box helicase 58
chr22_+_31496275 Show fit	4.44	ENST00000432498.5	SFI1 Links Ensembl NCBI GeneCards UniProt Show fit	SFI1 centrin binding protein
chr16_-_28211908 Show fit	4.44	ENST00000566073.1 ENST00000304658.10	XPO6 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 6
chr19_+_10086305 Show fit	4.42	ENST00000253110.16 ENST00000591813.5	SHFL Links Ensembl NCBI GeneCards UniProt Show fit	shiftless antiviral inhibitor of ribosomal frameshifting
chr20_+_408030 Show fit	4.36	ENST00000640614.1 ENST00000475269.5	RBCK1 Links Ensembl NCBI GeneCards UniProt Show fit	RANBP2-type and C3HC4-type zinc finger containing 1
chr22_+_36253124 Show fit	4.24	ENST00000438034.5 ENST00000427990.5 ENST00000397278.8 ENST00000397279.8 ENST00000433768.5	APOL1 Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L1
chr2_+_201116396 Show fit	4.21	ENST00000395148.6	CFLAR Links Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr12_+_6452024 Show fit	4.18	ENST00000266556.8 ENST00000544021.5	TAPBPL Links Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein like
chr20_-_35284745 Show fit	4.12	ENST00000374443.7 ENST00000374450.8	EIF6 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 6
chr4_-_73982019 Show fit	4.04	ENST00000296029.4	PF4 Links Ensembl NCBI GeneCards UniProt Show fit	platelet factor 4
chr20_-_35284715 Show fit	4.00	ENST00000374436.7 ENST00000675032.1	EIF6 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 6
chr22_+_39077264 Show fit	3.98	ENST00000407997.4	APOBEC3G Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr22_+_31496139 Show fit	3.97	ENST00000540643.5	SFI1 Links Ensembl NCBI GeneCards UniProt Show fit	SFI1 centrin binding protein
chr3_+_155870623 Show fit	3.74	ENST00000295920.7 ENST00000496455.7	GMPS Links Ensembl NCBI GeneCards UniProt Show fit	guanine monophosphate synthase
chr19_+_49474561 Show fit	3.73	ENST00000594009.5 ENST00000595510.1 ENST00000595815.1	FLT3LG Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000273189.1 Links Ensembl NCBI GeneCards UniProt Show fit	fms related receptor tyrosine kinase 3 ligand novel transcript
chr19_-_46714269 Show fit	3.62	ENST00000600194.5	PRKD2 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase D2
chr5_-_136365476 Show fit	3.56	ENST00000378459.7 ENST00000502753.4 ENST00000513104.6 ENST00000352189.8	TRPC7 Links Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 7
chr7_-_106285898 Show fit	3.53	ENST00000424768.2 ENST00000681255.1	NAMPT Links Ensembl NCBI GeneCards UniProt Show fit	nicotinamide phosphoribosyltransferase
chr2_+_189857393 Show fit	3.49	ENST00000452382.1	PMS1 Links Ensembl NCBI GeneCards UniProt Show fit	PMS1 homolog 1, mismatch repair system component
chr4_+_118034480 Show fit	3.42	ENST00000296499.6	NDST3 Links Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase and N-sulfotransferase 3
chr15_-_55319107 Show fit	3.39	ENST00000565225.1 ENST00000436697.3 ENST00000567948.1 ENST00000563262.5	PIGBOS1 Links Ensembl NCBI GeneCards UniProt Show fit RAB27A Links Ensembl NCBI GeneCards UniProt Show fit	PIGB opposite strand 1 RAB27A, member RAS oncogene family
chr4_-_86934700 Show fit	3.37	ENST00000473559.5	ENSG00000285458.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr3_+_42149222 Show fit	3.35	ENST00000449246.5 ENST00000613405.4	TRAK1 Links Ensembl NCBI GeneCards UniProt Show fit	trafficking kinesin protein 1
chr22_+_31496387 Show fit	3.28	ENST00000443011.5 ENST00000400288.7 ENST00000400289.5 ENST00000444859.5	SFI1 Links Ensembl NCBI GeneCards UniProt Show fit	SFI1 centrin binding protein
chr19_+_49474208 Show fit	3.09	ENST00000597551.6 ENST00000596435.5 ENST00000204637.6 ENST00000600429.5	FLT3LG Links Ensembl NCBI GeneCards UniProt Show fit	fms related receptor tyrosine kinase 3 ligand
chr11_-_4393650 Show fit	3.07	ENST00000254436.8	TRIM21 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 21
chr1_+_75724431 Show fit	3.04	ENST00000541113.6 ENST00000680805.1	ACADM Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA dehydrogenase medium chain
chr15_+_44711487 Show fit	2.96	ENST00000544417.5 ENST00000559916.1 ENST00000648006.3	B2M Links Ensembl NCBI GeneCards UniProt Show fit	beta-2-microglobulin
chr14_+_34982674 Show fit	2.86	ENST00000554803.5 ENST00000546080.6 ENST00000555746.6 ENST00000678963.1	SRP54 Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle 54
chr7_+_101085464 Show fit	2.85	ENST00000306085.11 ENST00000412507.1	TRIM56 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 56
chr1_-_154608140 Show fit	2.81	ENST00000529168.2 ENST00000368474.9 ENST00000680305.1 ENST00000648231.2	ADAR Links Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase RNA specific
chr7_-_106284524 Show fit	2.68	ENST00000681936.1 ENST00000680786.1 ENST00000681550.1	NAMPT Links Ensembl NCBI GeneCards UniProt Show fit	nicotinamide phosphoribosyltransferase
chr5_-_96807899 Show fit	2.67	ENST00000503921.5 ENST00000508227.5 ENST00000507154.1 ENST00000443439.7	ERAP1 Links Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum aminopeptidase 1
chr6_+_31572279 Show fit	2.66	ENST00000418386.3	LTA Links Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin alpha
chr6_+_26402289 Show fit	2.60	ENST00000414912.2	BTN3A1 Links Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A1
chr3_+_63912588 Show fit	2.55	ENST00000522345.2	ATXN7 Links Ensembl NCBI GeneCards UniProt Show fit	ataxin 7
chr20_+_408278 Show fit	2.47	ENST00000356286.10 ENST00000382181.2 ENST00000400247.3	RBCK1 Links Ensembl NCBI GeneCards UniProt Show fit	RANBP2-type and C3HC4-type zinc finger containing 1
chr10_-_14954018 Show fit	2.44	ENST00000378241.5 ENST00000456122.1 ENST00000418843.5 ENST00000378249.5 ENST00000396817.6 ENST00000378255.5 ENST00000378254.5 ENST00000357717.6 ENST00000378258.5 ENST00000378246.6 ENST00000378278.7	DCLRE1C Links Ensembl NCBI GeneCards UniProt Show fit	DNA cross-link repair 1C
chr2_+_201116143 Show fit	2.43	ENST00000443227.5 ENST00000309955.8 ENST00000341222.10 ENST00000341582.10	CFLAR Links Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr14_-_24146314 Show fit	2.41	ENST00000559056.5	PSME2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 2
chr19_-_47232649 Show fit	2.32	ENST00000449228.5 ENST00000300880.11 ENST00000341983.8	BBC3 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 binding component 3
chr10_-_22003678 Show fit	2.26	ENST00000376980.8	DNAJC1 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C1
chr13_+_108629605 Show fit	2.22	ENST00000457511.7	MYO16 Links Ensembl NCBI GeneCards UniProt Show fit	myosin XVI
chrX_+_77899440 Show fit	2.19	ENST00000373335.4 ENST00000475465.1 ENST00000650309.2 ENST00000647835.1	COX7B Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 7B
chr20_-_63216102 Show fit	2.01	ENST00000370339.8 ENST00000370334.4	YTHDF1 Links Ensembl NCBI GeneCards UniProt Show fit	YTH N6-methyladenosine RNA binding protein 1
chr1_+_75724672 Show fit	1.98	ENST00000370834.9 ENST00000370841.9 ENST00000679687.1 ENST00000420607.6	ACADM Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA dehydrogenase medium chain
chr12_-_98894830 Show fit	1.96	ENST00000549797.5 ENST00000333732.11 ENST00000341752.11	ANKS1B Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_22589240 Show fit	1.94	ENST00000450780.6 ENST00000430850.6 ENST00000447849.2 ENST00000614502.4 ENST00000443561.3	ENSG00000248235.6 Links Ensembl NCBI GeneCards UniProt Show fit PDLIM2 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein PDZ and LIM domain 2
chr2_-_37157093 Show fit	1.94	ENST00000681507.1	EIF2AK2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 alpha kinase 2
chr15_+_55319202 Show fit	1.93	ENST00000164305.10 ENST00000566999.5 ENST00000539642.5	PIGB Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class B
chr3_+_63911929 Show fit	1.93	ENST00000487717.5	ATXN7 Links Ensembl NCBI GeneCards UniProt Show fit	ataxin 7
chrX_+_147912039 Show fit	1.84	ENST00000334557.10 ENST00000439526.6	FMR1 Links Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1
chr11_+_5624987 Show fit	1.84	ENST00000429814.3	TRIM34 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 34
chr3_-_127591036 Show fit	1.77	ENST00000489960.5 ENST00000490290.5	TPRA1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein adipocyte associated 1
chr15_+_64136330 Show fit	1.76	ENST00000560861.1	SNX1 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 1
chr19_+_50384323 Show fit	1.75	ENST00000599857.7 ENST00000613923.6 ENST00000601098.6 ENST00000440232.7 ENST00000595904.6 ENST00000593887.1	POLD1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase delta 1, catalytic subunit
chr1_+_75724597 Show fit	1.73	ENST00000681790.1	ACADM Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA dehydrogenase medium chain
chr4_+_86934976 Show fit	1.59	ENST00000507468.5 ENST00000395146.9	AFF1 Links Ensembl NCBI GeneCards UniProt Show fit	AF4/FMR2 family member 1
chr11_+_118359572 Show fit	1.53	ENST00000252108.8 ENST00000431736.6	UBE4A Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitination factor E4A
chr15_+_75201873 Show fit	1.51	ENST00000394987.5	C15orf39 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 15 open reading frame 39
chr2_-_37156942 Show fit	1.47	ENST00000680273.1 ENST00000233057.9 ENST00000679979.1 ENST00000679507.1 ENST00000681463.1 ENST00000395127.6	EIF2AK2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 alpha kinase 2
chr14_+_34982963 Show fit	1.46	ENST00000678627.1 ENST00000216774.11 ENST00000555557.5	SRP54 Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle 54
chrX_+_147911943 Show fit	1.45	ENST00000621453.4 ENST00000218200.12 ENST00000370471.7 ENST00000440235.6 ENST00000370477.5 ENST00000621987.4	FMR1 Links Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1
chr17_+_6755834 Show fit	1.45	ENST00000346752.8	XAF1 Links Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr6_+_31571957 Show fit	1.37	ENST00000454783.5	LTA Links Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin alpha
chr9_-_137188540 Show fit	1.30	ENST00000323927.3	ANAPC2 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 2
chrX_+_147911910 Show fit	1.27	ENST00000370475.9	FMR1 Links Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1
chr4_+_99574812 Show fit	1.18	ENST00000422897.6 ENST00000265517.10	MTTP Links Ensembl NCBI GeneCards UniProt Show fit	microsomal triglyceride transfer protein
chr1_-_25420792 Show fit	1.17	ENST00000346452.8 ENST00000340849.8 ENST00000349438.8 ENST00000413854.5 ENST00000294413.13	RHCE Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group CcEe antigens
chr14_-_91510450 Show fit	1.13	ENST00000555462.5	PPP4R3A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 4 regulatory subunit 3A
chr2_+_99154955 Show fit	1.12	ENST00000393471.2 ENST00000393473.6 ENST00000651691.1 ENST00000449211.1 ENST00000434566.5 ENST00000410042.1	LIPT1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000273155.1 Links Ensembl NCBI GeneCards UniProt Show fit	lipoyltransferase 1 novel LIPT1-MRPL30 readthrough
chr15_+_56918763 Show fit	1.07	ENST00000557843.5	TCF12 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 12
chr4_+_143513661 Show fit	0.90	ENST00000283131.4	SMARCA5 Links Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr1_-_159076742 Show fit	0.86	ENST00000368130.9	AIM2 Links Ensembl NCBI GeneCards UniProt Show fit	absent in melanoma 2
chr1_+_236394268 Show fit	0.82	ENST00000334232.9	EDARADD Links Ensembl NCBI GeneCards UniProt Show fit	EDAR associated death domain
chr9_-_94640130 Show fit	0.81	ENST00000414122.1	FBP1 Links Ensembl NCBI GeneCards UniProt Show fit	fructose-bisphosphatase 1
chr11_+_124865425 Show fit	0.78	ENST00000397801.6	ROBO3 Links Ensembl NCBI GeneCards UniProt Show fit	roundabout guidance receptor 3
chr10_-_68471882 Show fit	0.75	ENST00000551118.6	DNA2 Links Ensembl NCBI GeneCards UniProt Show fit	DNA replication helicase/nuclease 2
chr2_-_219387784 Show fit	0.73	ENST00000520694.6	DNPEP Links Ensembl NCBI GeneCards UniProt Show fit	aspartyl aminopeptidase
chr17_+_6756035 Show fit	0.69	ENST00000361842.8 ENST00000574907.5	XAF1 Links Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr1_+_25272439 Show fit	0.68	ENST00000648012.1	RHD Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr3_-_195811916 Show fit	0.64	ENST00000463781.8	MUC4 Links Ensembl NCBI GeneCards UniProt Show fit	mucin 4, cell surface associated
chr1_+_25272502 Show fit	0.62	ENST00000328664.9	RHD Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr14_+_73058591 Show fit	0.60	ENST00000525161.5	RBM25 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 25
chr2_-_166494232 Show fit	0.58	ENST00000441411.2 ENST00000643258.1 ENST00000419992.6	SCN7A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 7
chr5_+_140691591 Show fit	0.55	ENST00000508522.5 ENST00000448069.2	HARS2 Links Ensembl NCBI GeneCards UniProt Show fit	histidyl-tRNA synthetase 2, mitochondrial
chr1_+_151156659 Show fit	0.55	ENST00000602841.5	SCNM1 Links Ensembl NCBI GeneCards UniProt Show fit	sodium channel modifier 1
chr2_+_69013170 Show fit	0.53	ENST00000303714.9	ANTXR1 Links Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr2_+_69013282 Show fit	0.43	ENST00000409829.7	ANTXR1 Links Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr20_+_62804794 Show fit	0.37	ENST00000290291.10	OGFR Links Ensembl NCBI GeneCards UniProt Show fit	opioid growth factor receptor
chr6_-_89819699 Show fit	0.36	ENST00000439638.1 ENST00000629399.2 ENST00000369393.8	MDN1 Links Ensembl NCBI GeneCards UniProt Show fit	midasin AAA ATPase 1
chr1_+_25272479 Show fit	0.35	ENST00000622561.4	RHD Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr4_+_87006988 Show fit	0.33	ENST00000307808.10	AFF1 Links Ensembl NCBI GeneCards UniProt Show fit	AF4/FMR2 family member 1
chr16_-_29862890 Show fit	0.31	ENST00000563415.1	CDIPT Links Ensembl NCBI GeneCards UniProt Show fit	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr22_+_39040857 Show fit	0.29	ENST00000381565.2 ENST00000308521.10	APOBEC3F Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3F
chr8_-_23069012 Show fit	0.29	ENST00000347739.3 ENST00000276431.9	TNFRSF10B Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 10b
chr6_+_31927486 Show fit	0.24	ENST00000442278.6	C2 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2
chr12_-_48570046 Show fit	0.19	ENST00000301046.6 ENST00000549817.1	LALBA Links Ensembl NCBI GeneCards UniProt Show fit	lactalbumin alpha
chr10_-_68471911 Show fit	0.16	ENST00000358410.8 ENST00000399180.3	DNA2 Links Ensembl NCBI GeneCards UniProt Show fit	DNA replication helicase/nuclease 2
chr4_+_87006736 Show fit	0.16	ENST00000544085.6	AFF1 Links Ensembl NCBI GeneCards UniProt Show fit	AF4/FMR2 family member 1
chr12_+_4649097 Show fit	0.15	ENST00000648836.1 ENST00000266544.10	ENSG00000255639.3 Links Ensembl NCBI GeneCards UniProt Show fit NDUFA9 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein NADH:ubiquinone oxidoreductase subunit A9
chr2_-_231125032 Show fit	0.13	ENST00000258400.4	HTR2B Links Ensembl NCBI GeneCards UniProt Show fit	5-hydroxytryptamine receptor 2B
chr12_+_133037476 Show fit	0.12	ENST00000540031.5 ENST00000539354.6 ENST00000536123.5	ZNF84 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 84
chr12_+_133037533 Show fit	0.12	ENST00000327668.11	ZNF84 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 84
chr1_-_89198868 Show fit	0.07	ENST00000355754.7	GBP4 Links Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 4
chr22_-_36703723 Show fit	0.07	ENST00000300105.7	CACNG2 Links Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit gamma 2
chr14_-_100375602 Show fit	0.04	ENST00000553395.5 ENST00000553545.5 ENST00000344102.9 ENST00000556338.5 ENST00000553934.1	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.6	19.7	GO:0046967	cytosol to ER transport(GO:0046967)
5.7	28.4	GO:0034343	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
4.8	14.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
4.7	28.5	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
4.4	13.2	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
3.4	27.5	GO:0032020	ISG15-protein conjugation(GO:0032020)
2.7	27.3	GO:0018377	protein myristoylation(GO:0018377)
2.2	6.7	GO:0051793	medium-chain fatty acid catabolic process(GO:0051793)
2.0	6.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
1.7	6.8	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
1.7	15.3	GO:1902570	protein localization to nucleolus(GO:1902570)
1.6	8.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
1.6	22.5	GO:0035457	cellular response to interferon-alpha(GO:0035457)
1.5	4.6	GO:1901252	modulation by host of viral RNA genome replication(GO:0044830) regulation of intracellular transport of viral material(GO:1901252) positive regulation of intracellular transport of viral material(GO:1901254)
1.5	3.0	GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
1.3	4.0	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
1.2	13.7	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.1	4.3	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
1.0	27.3	GO:0072643	interferon-gamma secretion(GO:0072643)
0.9	5.5	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.8	3.4	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.8	5.8	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.8	3.1	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.8	5.4	GO:0000255	allantoin metabolic process(GO:0000255)
0.7	3.7	GO:0006177	GMP biosynthetic process(GO:0006177)
0.7	4.3	GO:0070383	DNA cytosine deamination(GO:0070383)
0.7	6.0	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.7	2.0	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.6	7.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.6	11.7	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.6	4.0	GO:0045653	negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of megakaryocyte differentiation(GO:0045653)
0.6	3.4	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.6	2.8	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.5	5.4	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.5	53.5	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.5	3.4	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.5	0.9	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.4	3.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.4	4.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4	3.6	GO:0089700	protein kinase D signaling(GO:0089700)
0.4	6.2	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3	1.8	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	5.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.2	5.0	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.2	0.9	GO:0070269	pyroptosis(GO:0070269)
0.2	0.8	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.2	3.6	GO:0006828	manganese ion transport(GO:0006828)
0.2	1.2	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2	9.0	GO:0019835	cytolysis(GO:0019835)
0.1	1.8	GO:0040016	embryonic cleavage(GO:0040016)
0.1	1.8	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.1	11.7	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	0.9	GO:0016584	nucleosome positioning(GO:0016584)
0.1	1.1	GO:0009249	protein lipoylation(GO:0009249)
0.1	7.5	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.8	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	2.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	1.9	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.4	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.1	2.4	GO:0033151	V(D)J recombination(GO:0033151)
0.1	5.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	2.0	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	2.9	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	3.5	GO:0006298	mismatch repair(GO:0006298)
0.1	1.3	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	4.4	GO:0006611	protein export from nucleus(GO:0006611)
0.1	2.1	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.1	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0	1.7	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.6	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	1.0	GO:0015695	organic cation transport(GO:0015695)
0.0	2.3	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	1.2	GO:0070206	protein trimerization(GO:0070206)
0.0	0.4	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.1	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	1.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.0	1.8	GO:0021549	cerebellum development(GO:0021549)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	22.4	GO:0008537	proteasome activator complex(GO:0008537)
3.9	19.7	GO:0042825	TAP complex(GO:0042825)
2.9	20.5	GO:1990111	spermatoproteasome complex(GO:1990111)
1.5	4.6	GO:1902737	dendritic filopodium(GO:1902737)
1.3	4.0	GO:0097679	other organism cytoplasm(GO:0097679)
1.2	6.0	GO:0001652	dense fibrillar component(GO:0001651) granular component(GO:0001652)
1.1	4.3	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.0	6.0	GO:0071797	LUBAC complex(GO:0071797)
0.6	13.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.6	3.0	GO:0031905	early endosome lumen(GO:0031905)
0.5	4.3	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4	2.8	GO:0044530	supraspliceosomal complex(GO:0044530)
0.4	1.8	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.3	3.5	GO:0032389	MutLalpha complex(GO:0032389)
0.3	0.9	GO:0005760	gamma DNA polymerase complex(GO:0005760)
0.3	3.4	GO:0033093	Weibel-Palade body(GO:0033093)
0.3	8.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.3	9.0	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.3	1.8	GO:0030905	retromer, tubulation complex(GO:0030905)
0.2	16.4	GO:0015030	Cajal body(GO:0015030)
0.2	6.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	2.4	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.2	13.2	GO:0005771	multivesicular body(GO:0005771)
0.2	5.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2	0.9	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	2.2	GO:0045277	respiratory chain complex IV(GO:0045277)
0.1	5.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.9	GO:0016589	NURF complex(GO:0016589)
0.1	11.6	GO:0005814	centriole(GO:0005814)
0.1	3.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	3.4	GO:1904115	axon cytoplasm(GO:1904115)
0.1	3.6	GO:0005801	cis-Golgi network(GO:0005801)
0.1	7.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	7.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	18.4	GO:0016607	nuclear speck(GO:0016607)
0.0	14.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	2.1	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	4.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0099634	postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0	2.2	GO:0016459	myosin complex(GO:0016459)
0.0	0.4	GO:0031527	filopodium membrane(GO:0031527)
0.0	13.9	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	5.4	GO:0005769	early endosome(GO:0005769)
0.0	7.3	GO:0000139	Golgi membrane(GO:0000139)
0.0	62.5	GO:0005829	cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	14.4	GO:0008859	exoribonuclease II activity(GO:0008859)
3.4	20.6	GO:0046979	TAP2 binding(GO:0046979)
3.2	22.4	GO:0061133	endopeptidase activator activity(GO:0061133)
2.2	6.7	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
2.1	10.3	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
1.9	24.3	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.8	7.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
1.7	8.5	GO:0042296	ISG15 transferase activity(GO:0042296)
1.4	19.0	GO:0031386	protein tag(GO:0031386)
1.4	8.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.2	6.2	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)
1.1	12.6	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8	4.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.8	4.0	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.8	4.6	GO:0034046	poly(G) binding(GO:0034046)
0.7	20.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.7	4.3	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.7	3.4	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.6	13.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.6	3.4	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.6	5.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.5	13.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4	1.7	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
0.4	15.8	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4	6.0	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.4	3.6	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.4	1.9	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.4	1.1	GO:0016979	lipoate-protein ligase activity(GO:0016979)
0.4	1.8	GO:1990460	leptin receptor binding(GO:1990460)
0.3	2.4	GO:0035312	single-stranded DNA endodeoxyribonuclease activity(GO:0000014) 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2	3.7	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2	24.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.2	0.8	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2	5.4	GO:0048156	tau protein binding(GO:0048156)
0.2	1.8	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2	0.9	GO:0043139	site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890) 5'-3' DNA helicase activity(GO:0043139)
0.2	10.6	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.2	2.0	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.2	3.4	GO:0050811	GABA receptor binding(GO:0050811)
0.1	3.6	GO:0004697	protein kinase C activity(GO:0004697)
0.1	17.4	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	3.5	GO:0030983	mismatched DNA binding(GO:0030983)
0.1	3.4	GO:0031489	myosin V binding(GO:0031489)
0.1	0.6	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	4.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	5.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	4.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	9.0	GO:0005254	chloride channel activity(GO:0005254)
0.1	6.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	2.2	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.3	GO:0045569	TRAIL binding(GO:0045569)
0.1	2.3	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	4.0	GO:0019213	deacetylase activity(GO:0019213)
0.1	1.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	2.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.0	11.7	GO:0008017	microtubule binding(GO:0008017)
0.0	8.7	GO:0019902	phosphatase binding(GO:0019902)
0.0	1.0	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.4	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.6	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	2.2	GO:0003774	motor activity(GO:0003774)
0.0	5.4	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.0	2.3	GO:0051117	ATPase binding(GO:0051117)
0.0	5.6	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	2.1	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	1.2	GO:0005548	phospholipid transporter activity(GO:0005548)
0.0	0.9	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.6	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	6.9	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	20.1	GO:0042802	identical protein binding(GO:0042802)
0.0	0.1	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	13.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	5.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	15.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	10.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	5.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	18.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	6.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	15.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	3.4	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	4.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	5.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	3.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	46.6	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
1.1	24.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.9	89.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.7	46.9	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.4	12.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.4	6.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4	3.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.3	5.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	3.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	4.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	8.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2	2.7	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	10.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	5.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	3.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	3.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	5.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.9	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	5.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	0.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.3	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	3.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	4.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	2.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	4.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis