avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ISX Links Ensembl NCBI GeneCards UniProt	ENSG00000175329.13	ISX

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Promoter	Score	Transcript	Gene	Gene Info
chr12_+_104286881 Show fit	18.48	ENST00000526691.5 ENST00000531691.5 ENST00000526390.5 ENST00000531689.5	TXNRD1 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin reductase 1
chr1_-_197146620 Show fit	15.85	ENST00000367409.9 ENST00000680265.1	ASPM Links Ensembl NCBI GeneCards UniProt Show fit	assembly factor for spindle microtubules
chr1_-_197146688 Show fit	15.76	ENST00000294732.11	ASPM Links Ensembl NCBI GeneCards UniProt Show fit	assembly factor for spindle microtubules
chr5_+_178204522 Show fit	14.74	ENST00000506339.5 ENST00000358344.8 ENST00000355836.9 ENST00000514633.5 ENST00000515193.5 ENST00000506259.5 ENST00000504898.5	HNRNPAB Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A/B
chr10_+_123154768 Show fit	13.97	ENST00000407911.2	BUB3 Links Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr4_-_173334385 Show fit	13.26	ENST00000446922.6	HMGB2 Links Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 2
chr5_+_160421847 Show fit	12.94	ENST00000352433.10 ENST00000517480.1 ENST00000520452.5 ENST00000393964.1	PTTG1 Links Ensembl NCBI GeneCards UniProt Show fit	PTTG1 regulator of sister chromatid separation, securin
chr4_-_173334249 Show fit	12.30	ENST00000506267.1 ENST00000296503.10	HMGB2 Links Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 2
chr20_+_45812576 Show fit	11.42	ENST00000405520.5 ENST00000617055.4	UBE2C Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 C
chr20_+_45812665 Show fit	10.69	ENST00000352551.9	UBE2C Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 C
chr20_+_45812632 Show fit	10.58	ENST00000335046.7 ENST00000356455.9 ENST00000243893.10	UBE2C Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 C
chr1_+_220094086 Show fit	9.98	ENST00000366922.3	IARS2 Links Ensembl NCBI GeneCards UniProt Show fit	isoleucyl-tRNA synthetase 2, mitochondrial
chr16_-_31094549 Show fit	9.98	ENST00000394971.7	VKORC1 Links Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex subunit 1
chr22_-_41947087 Show fit	9.86	ENST00000407253.7 ENST00000215980.10	CENPM Links Ensembl NCBI GeneCards UniProt Show fit	centromere protein M
chr1_+_62437015 Show fit	9.57	ENST00000339950.5	USP1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 1
chr13_+_30422487 Show fit	9.53	ENST00000638137.1 ENST00000635918.2	UBE2L5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L5
chr22_+_23966880 Show fit	9.39	ENST00000215770.6	DDTL Links Ensembl NCBI GeneCards UniProt Show fit	D-dopachrome tautomerase like
chr22_-_41946688 Show fit	9.29	ENST00000404067.5 ENST00000402338.5	CENPM Links Ensembl NCBI GeneCards UniProt Show fit	centromere protein M
chrX_+_77899440 Show fit	8.48	ENST00000373335.4 ENST00000475465.1 ENST00000650309.2 ENST00000647835.1	COX7B Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 7B
chr11_-_111871530 Show fit	8.28	ENST00000614444.4 ENST00000616540.5	ALG9 Links Ensembl NCBI GeneCards UniProt Show fit	ALG9 alpha-1,2-mannosyltransferase
chr10_+_123154414 Show fit	8.27	ENST00000368858.9	BUB3 Links Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr6_+_30720335 Show fit	7.79	ENST00000327892.13	TUBB Links Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr19_-_10116827 Show fit	7.68	ENST00000593054.5	EIF3G Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit G
chr11_-_111871271 Show fit	7.57	ENST00000398006.6	ALG9 Links Ensembl NCBI GeneCards UniProt Show fit	ALG9 alpha-1,2-mannosyltransferase
chr1_+_155308748 Show fit	7.46	ENST00000611010.4 ENST00000447866.5 ENST00000368356.9 ENST00000467076.5 ENST00000491013.5 ENST00000356657.10	FDPS Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl diphosphate synthase
chr1_+_155308930 Show fit	7.32	ENST00000465559.5 ENST00000612683.1	FDPS Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl diphosphate synthase
chr17_-_79009731 Show fit	7.31	ENST00000392446.10 ENST00000590370.5 ENST00000591625.5	CANT1 Links Ensembl NCBI GeneCards UniProt Show fit	calcium activated nucleotidase 1
chr2_+_216659600 Show fit	7.11	ENST00000456764.1	IGFBP2 Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 2
chr16_+_3020359 Show fit	7.03	ENST00000341627.5 ENST00000326577.9 ENST00000575124.1 ENST00000575836.1	TNFRSF12A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 12A
chr5_-_178153858 Show fit	7.00	ENST00000514354.5 ENST00000274606.8 ENST00000511078.1	NHP2 Links Ensembl NCBI GeneCards UniProt Show fit	NHP2 ribonucleoprotein
chr1_-_150697128 Show fit	6.97	ENST00000427665.1 ENST00000271732.8	GOLPH3L Links Ensembl NCBI GeneCards UniProt Show fit	golgi phosphoprotein 3 like
chr6_+_36594354 Show fit	6.89	ENST00000373715.11	SRSF3 Links Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 3
chr5_-_178153776 Show fit	6.67	ENST00000314397.8	NHP2 Links Ensembl NCBI GeneCards UniProt Show fit	NHP2 ribonucleoprotein
chr7_-_87220567 Show fit	6.44	ENST00000433078.5	TMEM243 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 243
chr7_-_44573895 Show fit	6.20	ENST00000258772.10 ENST00000431640.5	DDX56 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 56
chr16_-_31094727 Show fit	6.07	ENST00000300851.10 ENST00000394975.3	VKORC1 Links Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex subunit 1
chr16_+_69424634 Show fit	6.01	ENST00000515314.6 ENST00000561792.6 ENST00000568237.1	CYB5B Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B
chr20_-_56392131 Show fit	6.01	ENST00000422322.5 ENST00000371356.6 ENST00000451915.1 ENST00000347343.6 ENST00000395911.5 ENST00000395915.8 ENST00000395907.5 ENST00000441357.5 ENST00000456249.5 ENST00000420474.5 ENST00000395914.5 ENST00000312783.10 ENST00000395913.7	AURKA Links Ensembl NCBI GeneCards UniProt Show fit	aurora kinase A
chr13_+_48037692 Show fit	5.98	ENST00000258662.3	NUDT15 Links Ensembl NCBI GeneCards UniProt Show fit	nudix hydrolase 15
chr1_+_62436297 Show fit	5.75	ENST00000452143.5 ENST00000442679.5 ENST00000371146.5	USP1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 1
chr18_+_58221535 Show fit	5.54	ENST00000431212.6 ENST00000586268.5 ENST00000587190.5	NEDD4L Links Ensembl NCBI GeneCards UniProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr16_-_31094890 Show fit	5.52	ENST00000532364.1 ENST00000529564.1 ENST00000319788.11 ENST00000354895.4	ENSG00000255439.6 Links Ensembl NCBI GeneCards UniProt Show fit VKORC1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, VKORC1 and PRSS53 readthrough vitamin K epoxide reductase complex subunit 1
chr4_+_109815503 Show fit	5.37	ENST00000394631.7	GAR1 Links Ensembl NCBI GeneCards UniProt Show fit	GAR1 ribonucleoprotein
chr10_+_123154364 Show fit	5.32	ENST00000368859.6 ENST00000368865.9	BUB3 Links Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr1_-_16978276 Show fit	5.29	ENST00000375534.7	MFAP2 Links Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 2
chr4_+_107989880 Show fit	5.28	ENST00000309522.8 ENST00000403312.6 ENST00000638559.1 ENST00000682373.1	HADH Links Ensembl NCBI GeneCards UniProt Show fit	hydroxyacyl-CoA dehydrogenase
chr7_+_55365317 Show fit	5.16	ENST00000254770.3	LANCL2 Links Ensembl NCBI GeneCards UniProt Show fit	LanC like 2
chr6_-_31862809 Show fit	5.11	ENST00000375631.5	NEU1 Links Ensembl NCBI GeneCards UniProt Show fit	neuraminidase 1
chr1_-_43367956 Show fit	4.86	ENST00000372458.8	ELOVL1 Links Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 1
chr17_-_7263959 Show fit	4.74	ENST00000571932.2	CLDN7 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 7
chr14_-_20333306 Show fit	4.64	ENST00000353689.8 ENST00000437553.6	CCNB1IP1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin B1 interacting protein 1
chr1_-_43368039 Show fit	4.43	ENST00000413844.3	ELOVL1 Links Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 1
chr14_-_20333268 Show fit	4.39	ENST00000358932.9 ENST00000557665.5	CCNB1IP1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin B1 interacting protein 1
chr1_+_23019415 Show fit	4.27	ENST00000465864.2 ENST00000356634.7 ENST00000400181.9	KDM1A Links Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 1A
chr17_-_31901658 Show fit	4.25	ENST00000261708.9	UTP6 Links Ensembl NCBI GeneCards UniProt Show fit	UTP6 small subunit processome component
chr10_-_1048879 Show fit	4.24	ENST00000429642.2	IDI1 Links Ensembl NCBI GeneCards UniProt Show fit	isopentenyl-diphosphate delta isomerase 1
chr8_+_109539696 Show fit	4.23	ENST00000395785.6	EBAG9 Links Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor binding site associated antigen 9
chr9_-_134068012 Show fit	4.18	ENST00000303407.12	BRD3 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 3
chr17_-_50707855 Show fit	4.13	ENST00000285243.7	ANKRD40 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 40
chr10_-_1049110 Show fit	4.12	ENST00000381344.8	IDI1 Links Ensembl NCBI GeneCards UniProt Show fit	isopentenyl-diphosphate delta isomerase 1
chr6_-_111606260 Show fit	3.88	ENST00000340026.10	TRAF3IP2 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 2
chr4_+_107989714 Show fit	3.78	ENST00000505878.4 ENST00000603302.5 ENST00000638621.1	HADH Links Ensembl NCBI GeneCards UniProt Show fit	hydroxyacyl-CoA dehydrogenase
chr3_-_165837412 Show fit	3.72	ENST00000479451.5 ENST00000488954.1 ENST00000264381.8	BCHE Links Ensembl NCBI GeneCards UniProt Show fit	butyrylcholinesterase
chr20_-_44504850 Show fit	3.72	ENST00000411544.5	SERINC3 Links Ensembl NCBI GeneCards UniProt Show fit	serine incorporator 3
chr8_+_109540075 Show fit	3.58	ENST00000614147.1 ENST00000337573.10	EBAG9 Links Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor binding site associated antigen 9
chr7_+_120988683 Show fit	3.56	ENST00000340646.9 ENST00000310396.10	CPED1 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin like and PC-esterase domain containing 1
chr11_+_95790459 Show fit	3.56	ENST00000325486.9 ENST00000325542.10 ENST00000544522.5 ENST00000541365.5	CEP57 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 57
chr16_+_69424610 Show fit	3.55	ENST00000307892.13	CYB5B Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B
chr12_+_56080155 Show fit	3.51	ENST00000267101.8	ERBB3 Links Ensembl NCBI GeneCards UniProt Show fit	erb-b2 receptor tyrosine kinase 3
chr17_-_79009778 Show fit	3.40	ENST00000591773.5 ENST00000588611.5 ENST00000586916.6 ENST00000592033.5 ENST00000588075.5 ENST00000302345.6 ENST00000591811.1	CANT1 Links Ensembl NCBI GeneCards UniProt Show fit	calcium activated nucleotidase 1
chr11_+_75815180 Show fit	3.39	ENST00000356136.8	UVRAG Links Ensembl NCBI GeneCards UniProt Show fit	UV radiation resistance associated
chr17_+_47209035 Show fit	3.34	ENST00000572316.5 ENST00000354968.5 ENST00000576874.5 ENST00000536623.6	MYL4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr10_+_47322450 Show fit	3.33	ENST00000581492.3	GDF2 Links Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 2
chr1_-_23344314 Show fit	3.23	ENST00000374612.5 ENST00000675048.1 ENST00000478691.5	HNRNPR Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr7_+_151232464 Show fit	3.23	ENST00000482173.5 ENST00000495645.5 ENST00000035307.6	CHPF2 Links Ensembl NCBI GeneCards UniProt Show fit	chondroitin polymerizing factor 2
chr10_-_5813387 Show fit	3.23	ENST00000456041.5 ENST00000380181.7 ENST00000418688.5 ENST00000609712.1 ENST00000380191.9	GDI2 Links Ensembl NCBI GeneCards UniProt Show fit	GDP dissociation inhibitor 2
chr11_-_62573846 Show fit	3.21	ENST00000329251.5	EEF1G Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 gamma
chr10_-_112446932 Show fit	3.17	ENST00000682195.1 ENST00000683505.1 ENST00000683895.1 ENST00000682839.1 ENST00000682055.1	ZDHHC6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 6
chr22_-_28741783 Show fit	3.16	ENST00000439200.5 ENST00000405598.5 ENST00000398017.3 ENST00000649563.1 ENST00000650281.1 ENST00000425190.7 ENST00000404276.6 ENST00000650233.1 ENST00000348295.7 ENST00000382580.6	CHEK2 Links Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chr8_+_10095704 Show fit	3.15	ENST00000382490.9	MSRA Links Ensembl NCBI GeneCards UniProt Show fit	methionine sulfoxide reductase A
chr5_-_83673544 Show fit	3.07	ENST00000503117.1 ENST00000510978.5	HAPLN1 Links Ensembl NCBI GeneCards UniProt Show fit	hyaluronan and proteoglycan link protein 1
chr8_+_10095551 Show fit	3.04	ENST00000522907.5 ENST00000528246.5	MSRA Links Ensembl NCBI GeneCards UniProt Show fit	methionine sulfoxide reductase A
chr5_+_177384430 Show fit	3.01	ENST00000512593.5 ENST00000324417.6	SLC34A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 34 member 1
chr11_-_62646598 Show fit	2.94	ENST00000648273.1 ENST00000356638.8 ENST00000346178.8 ENST00000534779.5 ENST00000525994.1 ENST00000540933.5	GANAB Links Ensembl NCBI GeneCards UniProt Show fit	glucosidase II alpha subunit
chr1_-_23344259 Show fit	2.93	ENST00000476451.2 ENST00000302271.11 ENST00000606561.5 ENST00000374616.7	HNRNPR Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr22_+_23980123 Show fit	2.88	ENST00000621118.4	GSTT2 Links Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase theta 2 (gene/pseudogene)
chr4_-_65670339 Show fit	2.84	ENST00000273854.7	EPHA5 Links Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A5
chr4_-_65670478 Show fit	2.67	ENST00000613740.5 ENST00000622150.4 ENST00000511294.1	EPHA5 Links Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A5
chrX_+_152759218 Show fit	2.66	ENST00000599845.3 ENST00000638835.1	CSAG3 Links Ensembl NCBI GeneCards UniProt Show fit	CSAG family member 3
chr12_+_14973020 Show fit	2.57	ENST00000266395.3	PDE6H Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 6H
chr8_+_109539816 Show fit	2.56	ENST00000529931.1	EBAG9 Links Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor binding site associated antigen 9
chr12_-_10802627 Show fit	2.49	ENST00000240687.2	TAS2R7 Links Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 7
chr12_-_56645955 Show fit	2.45	ENST00000552959.5 ENST00000551020.5 ENST00000553007.2 ENST00000262030.8	ATP5F1B Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase F1 subunit beta
chr10_+_89701580 Show fit	2.40	ENST00000371728.8 ENST00000260753.8	KIF20B Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 20B
chr6_-_33418077 Show fit	2.38	ENST00000488478.5	CUTA Links Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr9_+_34646654 Show fit	2.38	ENST00000378842.8	GALT Links Ensembl NCBI GeneCards UniProt Show fit	galactose-1-phosphate uridylyltransferase
chr15_+_64387828 Show fit	2.28	ENST00000261884.8	TRIP4 Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 4
chr3_+_148991408 Show fit	2.24	ENST00000627418.2 ENST00000296048.10 ENST00000483267.5 ENST00000345003.9 ENST00000484197.5	GYG1 Links Ensembl NCBI GeneCards UniProt Show fit	glycogenin 1
chr10_-_112446891 Show fit	2.24	ENST00000369404.3 ENST00000369405.7 ENST00000626395.2	ZDHHC6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 6
chr9_+_34646589 Show fit	2.15	ENST00000450095.6	GALT Links Ensembl NCBI GeneCards UniProt Show fit	galactose-1-phosphate uridylyltransferase
chr11_+_77821187 Show fit	2.14	ENST00000525409.5	AAMDC Links Ensembl NCBI GeneCards UniProt Show fit	adipogenesis associated Mth938 domain containing
chr19_-_6424802 Show fit	2.10	ENST00000600480.2	KHSRP Links Ensembl NCBI GeneCards UniProt Show fit	KH-type splicing regulatory protein
chr3_-_15521675 Show fit	2.03	ENST00000383788.10 ENST00000383786.9 ENST00000603808.5	COLQ Links Ensembl NCBI GeneCards UniProt Show fit	collagen like tail subunit of asymmetric acetylcholinesterase
chr10_-_112446734 Show fit	2.00	ENST00000684507.1	ZDHHC6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 6
chr7_+_130381092 Show fit	2.00	ENST00000484324.1	CPA1 Links Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A1
chr6_-_30113086 Show fit	2.00	ENST00000376734.4	TRIM31 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 31
chr17_+_42288429 Show fit	2.00	ENST00000676631.1 ENST00000677893.1	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr7_+_116222804 Show fit	2.00	ENST00000393481.6	TES Links Ensembl NCBI GeneCards UniProt Show fit	testin LIM domain protein
chr17_+_48892761 Show fit	1.99	ENST00000355938.9 ENST00000393366.7 ENST00000503641.5 ENST00000514808.5 ENST00000506855.1	ATP5MC1 Links Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 1
chr16_+_11965193 Show fit	1.98	ENST00000053243.6 ENST00000396495.3	TNFRSF17 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 17
chrX_-_152709260 Show fit	1.97	ENST00000535353.3 ENST00000638741.1 ENST00000640702.1	CSAG2 Links Ensembl NCBI GeneCards UniProt Show fit	CSAG family member 2
chr16_+_11965234 Show fit	1.97	ENST00000562385.1	TNFRSF17 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 17
chr6_-_33417878 Show fit	1.89	ENST00000440279.7 ENST00000607266.5	CUTA Links Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr5_+_174724549 Show fit	1.83	ENST00000239243.7 ENST00000507785.2	MSX2 Links Ensembl NCBI GeneCards UniProt Show fit	msh homeobox 2
chr12_-_10826358 Show fit	1.81	ENST00000240619.2	TAS2R10 Links Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 10
chr9_+_133636355 Show fit	1.70	ENST00000393056.8	DBH Links Ensembl NCBI GeneCards UniProt Show fit	dopamine beta-hydroxylase
chr2_-_79087986 Show fit	1.69	ENST00000305089.8	REG1B Links Ensembl NCBI GeneCards UniProt Show fit	regenerating family member 1 beta
chr14_-_50561119 Show fit	1.68	ENST00000555216.5	MAP4K5 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 5
chr16_-_30370396 Show fit	1.64	ENST00000409939.8	TBC1D10B Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 10B
chrX_-_24672654 Show fit	1.61	ENST00000379145.5	PCYT1B Links Ensembl NCBI GeneCards UniProt Show fit	phosphate cytidylyltransferase 1, choline, beta
chr1_+_27934980 Show fit	1.61	ENST00000373894.8	SMPDL3B Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3B
chr2_+_86907953 Show fit	1.51	ENST00000409776.6	RGPD1 Links Ensembl NCBI GeneCards UniProt Show fit	RANBP2 like and GRIP domain containing 1
chr6_-_111605859 Show fit	1.49	ENST00000651359.1 ENST00000650859.1 ENST00000359831.8 ENST00000368761.11	TRAF3IP2 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 2
chr17_+_81683963 Show fit	1.42	ENST00000676462.1 ENST00000679336.1 ENST00000678196.1 ENST00000677243.1 ENST00000677044.1 ENST00000677109.1 ENST00000677484.1 ENST00000678105.1 ENST00000677209.1 ENST00000329138.9 ENST00000677225.1 ENST00000678866.1 ENST00000676729.1 ENST00000572392.2 ENST00000577012.1	HGS Links Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_+_27935110 Show fit	1.38	ENST00000549094.1	SMPDL3B Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3B
chrX_+_77910656 Show fit	1.37	ENST00000343533.9 ENST00000341514.11 ENST00000645454.1 ENST00000642651.1 ENST00000644362.1	ATP7A Links Ensembl NCBI GeneCards UniProt Show fit PGK1 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase copper transporting alpha phosphoglycerate kinase 1
chr1_+_27935022 Show fit	1.37	ENST00000411604.5 ENST00000373888.8	SMPDL3B Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3B
chrX_+_109535775 Show fit	1.36	ENST00000218004.5	NXT2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear transport factor 2 like export factor 2
chrX_+_19343893 Show fit	1.33	ENST00000540249.5 ENST00000545074.5 ENST00000379806.9 ENST00000423505.5 ENST00000422285.7 ENST00000417819.5 ENST00000355808.9 ENST00000379805.3	PDHA1 Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase E1 subunit alpha 1
chr12_-_51028234 Show fit	1.32	ENST00000547688.7 ENST00000394904.9	SLC11A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 member 2
chr3_+_37243177 Show fit	1.31	ENST00000361924.6 ENST00000444882.5 ENST00000356847.8 ENST00000617480.4 ENST00000450863.6 ENST00000429018.5	GOLGA4 Links Ensembl NCBI GeneCards UniProt Show fit	golgin A4
chr3_+_114056728 Show fit	1.25	ENST00000485050.5 ENST00000281273.8 ENST00000479882.5 ENST00000493014.1	QTRT2 Links Ensembl NCBI GeneCards UniProt Show fit	queuine tRNA-ribosyltransferase accessory subunit 2
chr22_-_23961153 Show fit	1.24	ENST00000404172.3 ENST00000290765.9	GSTT2B Links Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase theta 2B
chr6_-_33418093 Show fit	1.23	ENST00000488034.6	CUTA Links Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr3_-_165078480 Show fit	1.21	ENST00000264382.8	SI Links Ensembl NCBI GeneCards UniProt Show fit	sucrase-isomaltase
chr10_-_124418912 Show fit	1.19	ENST00000368845.6 ENST00000539214.5	OAT Links Ensembl NCBI GeneCards UniProt Show fit	ornithine aminotransferase
chr12_-_21910853 Show fit	1.18	ENST00000544039.5	ABCC9 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 9
chr19_-_45782479 Show fit	1.05	ENST00000447742.6 ENST00000354227.9 ENST00000291270.9 ENST00000683086.1 ENST00000343373.10	DMPK Links Ensembl NCBI GeneCards UniProt Show fit	DM1 protein kinase
chr6_-_33418046 Show fit	0.97	ENST00000494751.5 ENST00000374496.3	CUTA Links Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr1_-_68232514 Show fit	0.96	ENST00000262348.9 ENST00000370973.2 ENST00000370971.1	WLS Links Ensembl NCBI GeneCards UniProt Show fit	Wnt ligand secretion mediator
chr17_+_80991824 Show fit	0.94	ENST00000325167.9	CHMP6 Links Ensembl NCBI GeneCards UniProt Show fit	charged multivesicular body protein 6
chr2_-_55296361 Show fit	0.93	ENST00000647547.1	CCDC88A Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr3_-_151316795 Show fit	0.87	ENST00000260843.5	GPR87 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 87
chr1_-_68232539 Show fit	0.81	ENST00000370976.7 ENST00000354777.6	WLS Links Ensembl NCBI GeneCards UniProt Show fit	Wnt ligand secretion mediator
chr10_+_1049476 Show fit	0.76	ENST00000358220.5	WDR37 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 37
chr17_+_42288464 Show fit	0.74	ENST00000590726.7 ENST00000678903.1 ENST00000590949.6 ENST00000676585.1 ENST00000588868.5	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr11_-_13495984 Show fit	0.73	ENST00000282091.6	PTH Links Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr19_+_12891151 Show fit	0.69	ENST00000589039.5 ENST00000591470.5 ENST00000222214.10 ENST00000588905.5 ENST00000587072.1	GCDH Links Ensembl NCBI GeneCards UniProt Show fit	glutaryl-CoA dehydrogenase
chr15_+_58138368 Show fit	0.67	ENST00000219919.9 ENST00000536493.1	AQP9 Links Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr2_+_86720282 Show fit	0.66	ENST00000283632.5	RMND5A Links Ensembl NCBI GeneCards UniProt Show fit	required for meiotic nuclear division 5 homolog A
chr14_-_94323324 Show fit	0.63	ENST00000341584.4	SERPINA6 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 6
chr16_+_2429427 Show fit	0.62	ENST00000397066.9	CCNF Links Ensembl NCBI GeneCards UniProt Show fit	cyclin F
chrX_+_44844015 Show fit	0.53	ENST00000339042.6	DUSP21 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 21
chr5_+_141177790 Show fit	0.49	ENST00000239444.4 ENST00000623995.1	PCDHB8 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000279472.1 Links Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 8 novel transcript
chr6_-_33418125 Show fit	0.46	ENST00000492510.1 ENST00000374500.10	CUTA Links Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr7_+_142111739 Show fit	0.45	ENST00000550469.6 ENST00000477922.3	MGAM2 Links Ensembl NCBI GeneCards UniProt Show fit	maltase-glucoamylase 2 (putative)
chr11_+_77821125 Show fit	0.43	ENST00000526415.5 ENST00000393427.6 ENST00000527134.5 ENST00000304716.12 ENST00000630098.2	AAMDC Links Ensembl NCBI GeneCards UniProt Show fit	adipogenesis associated Mth938 domain containing
chr11_+_92969651 Show fit	0.36	ENST00000257068.3 ENST00000528076.1	MTNR1B Links Ensembl NCBI GeneCards UniProt Show fit	melatonin receptor 1B
chr17_-_4967790 Show fit	0.35	ENST00000575142.5 ENST00000206020.8	SPAG7 Links Ensembl NCBI GeneCards UniProt Show fit	sperm associated antigen 7
chr13_+_108629605 Show fit	0.33	ENST00000457511.7	MYO16 Links Ensembl NCBI GeneCards UniProt Show fit	myosin XVI
chr17_-_3063607 Show fit	0.31	ENST00000575751.1	OR1D5 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 1 subfamily D member 5
chr17_-_47189176 Show fit	0.31	ENST00000531206.5 ENST00000527547.5 ENST00000575483.5 ENST00000066544.8	CDC27 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 27
chr20_-_52105644 Show fit	0.30	ENST00000371523.8	ZFP64 Links Ensembl NCBI GeneCards UniProt Show fit	ZFP64 zinc finger protein
chr5_+_54455661 Show fit	0.23	ENST00000302005.3	HSPB3 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 3
chr8_+_49911604 Show fit	0.21	ENST00000642164.1 ENST00000644093.1 ENST00000643999.1 ENST00000647073.1 ENST00000646880.1	SNTG1 Links Ensembl NCBI GeneCards UniProt Show fit	syntrophin gamma 1
chr4_-_68670648 Show fit	0.15	ENST00000338206.6	UGT2B15 Links Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B15
chr2_+_62705644 Show fit	0.11	ENST00000427809.5 ENST00000405482.5 ENST00000431489.6	EHBP1 Links Ensembl NCBI GeneCards UniProt Show fit	EH domain binding protein 1
chr19_-_6424772 Show fit	0.10	ENST00000619396.4 ENST00000398148.7	KHSRP Links Ensembl NCBI GeneCards UniProt Show fit	KH-type splicing regulatory protein
chr2_+_62705866 Show fit	0.03	ENST00000263991.9	EHBP1 Links Ensembl NCBI GeneCards UniProt Show fit	EH domain binding protein 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.5	31.6	GO:0009786	regulation of asymmetric cell division(GO:0009786)
3.6	32.7	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
3.0	14.8	GO:0045337	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
2.7	13.7	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
2.7	5.4	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
2.3	18.5	GO:0001887	selenium compound metabolic process(GO:0001887)
2.1	25.6	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
2.0	6.0	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
1.8	21.6	GO:0042373	vitamin K metabolic process(GO:0042373)
1.7	5.2	GO:1901421	positive regulation of response to alcohol(GO:1901421)
1.7	8.4	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.5	4.5	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
1.2	3.7	GO:0014016	neuroblast differentiation(GO:0014016)
1.2	7.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.2	9.3	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.1	4.3	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
1.1	3.2	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.0	9.0	GO:0051026	chiasma assembly(GO:0051026)
1.0	3.0	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
1.0	15.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.9	7.7	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.8	15.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.8	38.3	GO:2000816	negative regulation of mitotic sister chromatid separation(GO:2000816)
0.8	2.4	GO:1903436	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.8	6.2	GO:0030091	protein repair(GO:0030091)
0.8	10.0	GO:0006450	regulation of translational fidelity(GO:0006450)
0.8	5.3	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.6	5.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.6	7.0	GO:0048194	Golgi vesicle budding(GO:0048194)
0.6	1.8	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.5	6.0	GO:0042262	DNA protection(GO:0042262)
0.5	19.2	GO:0061641	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5	2.0	GO:0006581	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.5	3.4	GO:1901098	double-strand break repair via classical nonhomologous end joining(GO:0097680) positive regulation of autophagosome maturation(GO:1901098)
0.5	3.7	GO:0009597	detection of virus(GO:0009597)
0.5	5.5	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.5	1.8	GO:0051795	embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.5	1.4	GO:0060003	copper ion export(GO:0060003) cellular response to lead ion(GO:0071284) regulation of electron carrier activity(GO:1904732)
0.4	8.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4	4.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.4	2.7	GO:0000255	allantoin metabolic process(GO:0000255)
0.4	7.4	GO:0018345	protein palmitoylation(GO:0018345)
0.3	8.4	GO:0061157	mRNA destabilization(GO:0061157)
0.3	5.4	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.3	1.3	GO:0015692	lead ion transport(GO:0015692)
0.2	1.7	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.2	5.5	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.2	9.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.2	7.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2	1.2	GO:0044245	polysaccharide digestion(GO:0044245)
0.2	0.7	GO:0015722	canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.2	4.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	4.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) negative regulation of protein homooligomerization(GO:0032463)
0.2	0.9	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	1.2	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	1.6	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	3.3	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	1.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	10.7	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.1	2.4	GO:1903541	regulation of exosomal secretion(GO:1903541)
0.1	4.3	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	6.2	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	6.8	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	2.0	GO:1902186	negative regulation of viral transcription(GO:0032897) regulation of viral release from host cell(GO:1902186)
0.1	0.3	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1	7.3	GO:0006749	glutathione metabolic process(GO:0006749)
0.1	0.9	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	14.7	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.1	0.7	GO:0006568	tryptophan metabolic process(GO:0006568)
0.1	3.3	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.1	2.6	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1	1.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	6.9	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1	3.9	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	1.2	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	2.3	GO:0045661	regulation of myoblast differentiation(GO:0045661)
0.0	0.6	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.0	5.5	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.8	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.3	GO:0007091	metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.0	1.6	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	1.6	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	1.2	GO:0006400	tRNA modification(GO:0006400)
0.0	1.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.2	27.6	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
4.2	37.6	GO:0072687	meiotic spindle(GO:0072687)
2.7	19.0	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.1	33.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.9	4.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.6	11.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.5	8.5	GO:0045277	respiratory chain complex IV(GO:0045277)
0.5	1.4	GO:0033565	ESCRT-0 complex(GO:0033565)
0.3	7.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3	1.3	GO:0070826	paraferritin complex(GO:0070826)
0.3	5.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	20.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	53.7	GO:0000793	condensed chromosome(GO:0000793)
0.2	0.7	GO:0034657	GID complex(GO:0034657)
0.2	2.4	GO:1990023	mitotic spindle midzone(GO:1990023)
0.2	1.7	GO:0042584	chromaffin granule membrane(GO:0042584)
0.2	1.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	0.8	GO:0070545	PeBoW complex(GO:0070545)
0.1	4.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	4.9	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	4.3	GO:1990391	DNA repair complex(GO:1990391)
0.1	13.6	GO:0001650	fibrillar center(GO:0001650)
0.1	0.9	GO:0000815	ESCRT III complex(GO:0000815)
0.1	5.5	GO:0005771	multivesicular body(GO:0005771)
0.1	5.1	GO:0035580	specific granule lumen(GO:0035580)
0.1	4.4	GO:0031526	brush border membrane(GO:0031526)
0.1	0.5	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	10.0	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	8.4	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	2.0	GO:0005605	basal lamina(GO:0005605)
0.0	6.2	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	9.4	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	1.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	5.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	20.9	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	3.7	GO:0016459	myosin complex(GO:0016459)
0.0	42.4	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	2.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	3.2	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.4	GO:0030897	HOPS complex(GO:0030897)
0.0	2.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	4.4	GO:0031225	anchored component of membrane(GO:0031225)
0.0	5.9	GO:0001726	ruffle(GO:0001726)
0.0	1.2	GO:0005903	brush border(GO:0005903)
0.0	2.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	6.2	GO:0015629	actin cytoskeleton(GO:0015629)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.9	GO:0036064	ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	25.6	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
4.0	15.9	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
3.6	21.6	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
3.6	10.7	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
3.0	14.8	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
2.7	19.0	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
2.0	6.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
1.7	5.1	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.7	18.5	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.7	10.0	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
1.2	6.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.2	9.3	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.1	3.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.1	4.3	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.9	3.7	GO:0033265	acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.7	2.2	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.7	32.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.7	1.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.7	6.0	GO:0035174	histone serine kinase activity(GO:0035174)
0.6	9.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.6	8.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.6	7.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.6	3.3	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.6	12.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5	6.9	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.5	4.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.5	4.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.5	5.5	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.5	4.5	GO:0070569	uridylyltransferase activity(GO:0070569)
0.4	0.4	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.4	4.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.4	7.4	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3	3.0	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3	1.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.3	1.6	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3	3.7	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3	5.5	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.3	10.4	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.3	1.2	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.3	8.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3	7.8	GO:0032794	GTPase activating protein binding(GO:0032794)
0.3	1.7	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3	1.3	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2	0.7	GO:0015265	urea channel activity(GO:0015265)
0.2	1.2	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2	26.1	GO:0043130	ubiquitin binding(GO:0043130)
0.2	10.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2	4.3	GO:0030515	snoRNA binding(GO:0030515)
0.1	7.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	12.9	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	3.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	2.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.4	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	7.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	4.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	6.9	GO:0005507	copper ion binding(GO:0005507)
0.1	2.6	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	6.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	27.6	GO:0005516	calmodulin binding(GO:0005516)
0.1	2.4	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	1.8	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	1.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	3.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	2.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	2.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	6.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	3.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	7.4	GO:0020037	heme binding(GO:0020037)
0.0	0.9	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	9.4	GO:0016829	lyase activity(GO:0016829)
0.0	1.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.9	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	3.4	GO:0000149	SNARE binding(GO:0000149)
0.0	3.7	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	13.2	PID FANCONI PATHWAY	Fanconi anemia pathway
0.2	31.1	PID P73PATHWAY	p73 transcription factor network
0.1	13.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	9.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	5.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	6.0	PID AURORA A PATHWAY	Aurora A signaling
0.1	3.2	PID ATM PATHWAY	ATM pathway
0.1	8.9	PID NOTCH PATHWAY	Notch signaling pathway
0.1	2.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	3.3	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	3.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	3.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	5.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.7	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	1.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	60.6	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.7	25.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.3	15.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
1.0	19.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.6	10.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.6	23.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.6	18.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5	9.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5	15.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.5	3.2	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.4	13.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.3	9.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3	7.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	18.9	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2	3.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2	2.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	19.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	7.7	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	3.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	8.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	5.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	5.5	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	1.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	1.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	1.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	3.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	4.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	3.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	4.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	3.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.9	REACTOME TRANSLATION	Genes involved in Translation