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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for JDP2

Z-value: 0.76

Motif logo

Transcription factors associated with JDP2

Gene Symbol Gene ID Gene Info
ENSG00000140044.13 JDP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JDP2hg38_v1_chr14_+_75428011_754280460.152.5e-02Click!

Activity profile of JDP2 motif

Sorted Z-values of JDP2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_57628684 26.20 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr2_-_174847765 16.64 ENST00000443238.6
chimerin 1
chr2_-_174847525 16.33 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr13_-_44474296 10.27 ENST00000611198.4
TSC22 domain family member 1
chr20_+_4686320 9.87 ENST00000430350.2
prion protein
chr16_+_15502266 9.52 ENST00000452191.6
bMERB domain containing 1
chr3_-_98522869 8.73 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr7_+_48088596 7.79 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr12_+_10212867 7.67 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr5_+_136059151 7.32 ENST00000503087.1
transforming growth factor beta induced
chr3_+_69084929 7.26 ENST00000273258.4
ADP ribosylation factor like GTPase 6 interacting protein 5
chr7_+_97732046 6.88 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chr13_-_35855627 6.79 ENST00000379893.5
doublecortin like kinase 1
chr10_+_17228215 6.48 ENST00000544301.7
vimentin
chr5_-_150113344 6.43 ENST00000286301.7
ENST00000511344.1
colony stimulating factor 1 receptor
chr5_+_136058849 6.34 ENST00000508076.5
transforming growth factor beta induced
chr3_-_98522514 6.33 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr14_-_51095091 6.23 ENST00000684578.1
tripartite motif containing 9
chr3_+_69084973 6.13 ENST00000478935.1
ADP ribosylation factor like GTPase 6 interacting protein 5
chr3_+_184176778 5.94 ENST00000439647.5
adaptor related protein complex 2 subunit mu 1
chr16_+_57628507 5.69 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr2_-_223602284 5.68 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr3_+_184176949 5.52 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
adaptor related protein complex 2 subunit mu 1
chr8_-_27614681 5.34 ENST00000519472.5
ENST00000523589.5
ENST00000522413.5
ENST00000523396.1
ENST00000316403.15
clusterin
chr3_-_49358320 5.13 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
glutathione peroxidase 1
chr3_-_49358272 4.82 ENST00000419349.2
glutathione peroxidase 1
chr1_+_36155930 4.56 ENST00000316156.8
MAP7 domain containing 1
chr3_-_18424533 4.36 ENST00000417717.6
SATB homeobox 1
chr2_-_144517663 4.28 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr1_+_36156096 4.09 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr17_+_81683963 3.77 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_+_102808057 3.54 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr15_+_86079863 3.44 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr3_-_18425295 3.43 ENST00000338745.11
ENST00000450898.1
SATB homeobox 1
chr13_-_35855758 3.35 ENST00000615680.4
doublecortin like kinase 1
chr1_-_151992571 3.35 ENST00000368809.1
S100 calcium binding protein A10
chr3_+_141368497 3.27 ENST00000321464.7
zinc finger and BTB domain containing 38
chr3_-_114624979 3.14 ENST00000676079.1
zinc finger and BTB domain containing 20
chr1_+_223701582 3.13 ENST00000433674.6
calpain 2
chr12_-_119804298 3.12 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr16_+_89921851 3.10 ENST00000554444.5
ENST00000556565.5
tubulin beta 3 class III
chr3_-_114624921 3.07 ENST00000393785.6
zinc finger and BTB domain containing 20
chr12_-_119804472 2.97 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr7_+_23246697 2.94 ENST00000381990.6
ENST00000409458.3
ENST00000647578.1
ENST00000258733.9
glycoprotein nmb
chr11_-_2903490 2.84 ENST00000455942.3
ENST00000625099.4
solute carrier family 22 member 18 antisense
chr14_+_103334339 2.82 ENST00000558316.5
ENST00000558265.5
eukaryotic translation initiation factor 5
chr19_-_4455292 2.78 ENST00000394765.7
ENST00000592515.1
UBX domain protein 6
chr11_+_123590939 2.75 ENST00000646146.1
GRAM domain containing 1B
chr12_+_53098846 2.68 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr4_+_169660062 2.49 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chr17_-_75779758 2.35 ENST00000592643.5
ENST00000591890.5
ENST00000587171.1
ENST00000254810.8
ENST00000589599.5
H3.3 histone B
chr17_+_68249200 2.33 ENST00000577985.5
archaelysin family metallopeptidase 2
chr12_-_8066331 2.25 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chrX_-_49043345 2.24 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chr1_+_213051229 2.20 ENST00000615329.4
ENST00000543354.5
ENST00000614059.4
ENST00000543470.5
ENST00000366960.8
ENST00000366959.4
ribosomal protein S6 kinase C1
chr12_+_57520959 2.19 ENST00000551351.5
methyl-CpG binding domain protein 6
chr6_-_56954747 2.18 ENST00000680361.1
dystonin
chr12_-_130716264 2.15 ENST00000643940.1
RIMS binding protein 2
chr12_+_106774630 2.11 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr18_+_58196736 2.07 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_149576203 2.05 ENST00000472417.1
WW domain containing transcription regulator 1
chr8_-_140764386 2.02 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr3_-_45915698 2.01 ENST00000539217.5
leucine zipper transcription factor like 1
chr3_-_122793772 1.95 ENST00000306103.3
HSPB1 associated protein 1
chr16_+_28984795 1.87 ENST00000395461.7
linker for activation of T cells
chr3_+_156142962 1.80 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr11_-_2929412 1.71 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr16_+_28985043 1.70 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chrX_-_15270031 1.68 ENST00000380483.7
ENST00000380485.7
ENST00000380488.9
ankyrin repeat and SOCS box containing 9
chr16_+_30065753 1.65 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
aldolase, fructose-bisphosphate A
chr9_-_35112379 1.63 ENST00000488109.6
family with sequence similarity 214 member B
chr1_+_154405193 1.55 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr9_+_34958254 1.55 ENST00000242315.3
PHD finger protein 24
chr7_+_148133684 1.52 ENST00000628930.2
contactin associated protein 2
chr2_+_219627394 1.52 ENST00000373760.6
solute carrier family 4 member 3
chr6_+_63211446 1.50 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr16_+_30065777 1.47 ENST00000395240.7
ENST00000566846.5
aldolase, fructose-bisphosphate A
chr17_+_37491464 1.47 ENST00000613659.1
dual specificity phosphatase 14
chrX_+_154542194 1.41 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr16_+_31355215 1.41 ENST00000562522.2
integrin subunit alpha X
chr12_-_55707865 1.40 ENST00000347027.10
ENST00000257879.11
ENST00000553804.6
integrin subunit alpha 7
chr15_-_22980334 1.39 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
cytoplasmic FMR1 interacting protein 1
chr17_+_81098118 1.39 ENST00000416299.6
BAR/IMD domain containing adaptor protein 2
chr1_-_112704921 1.37 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr16_+_28985095 1.34 ENST00000454369.6
linker for activation of T cells
chr1_+_154405326 1.33 ENST00000368485.8
interleukin 6 receptor
chr2_+_219627650 1.33 ENST00000317151.7
solute carrier family 4 member 3
chr7_+_832488 1.32 ENST00000405266.5
ENST00000403868.5
ENST00000425407.6
Sad1 and UNC84 domain containing 1
chrY_+_12904860 1.28 ENST00000336079.8
DEAD-box helicase 3 Y-linked
chr9_-_89178810 1.28 ENST00000375835.9
SHC adaptor protein 3
chr2_+_219627565 1.25 ENST00000273063.10
solute carrier family 4 member 3
chr5_+_35856883 1.24 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr7_+_832470 1.23 ENST00000401592.6
Sad1 and UNC84 domain containing 1
chr10_-_73625951 1.23 ENST00000433394.1
ENST00000422491.7
ubiquitin specific peptidase 54
chr12_+_6535278 1.21 ENST00000396858.5
glyceraldehyde-3-phosphate dehydrogenase
chr1_+_89524871 1.20 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr16_+_31355165 1.18 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr2_+_219627622 1.16 ENST00000358055.8
solute carrier family 4 member 3
chr11_-_6006946 1.14 ENST00000641156.1
ENST00000641835.1
olfactory receptor family 56 subfamily A member 4
chr6_+_10521337 1.13 ENST00000495262.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr22_+_20507571 1.10 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr20_+_49812697 1.08 ENST00000417961.5
solute carrier family 9 member A8
chr4_+_73740541 1.07 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr1_+_151254709 1.07 ENST00000368881.8
ENST00000368884.8
proteasome 26S subunit, non-ATPase 4
chr17_-_35433250 1.05 ENST00000452764.3
schlafen family member 12
chr2_-_219308963 1.04 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
protein tyrosine phosphatase receptor type N
chr1_-_205775449 1.04 ENST00000235932.8
ENST00000437324.6
ENST00000414729.1
ENST00000367139.8
RAB29, member RAS oncogene family
chrX_+_47193796 0.99 ENST00000442035.5
ENST00000335972.11
ENST00000457753.5
ubiquitin like modifier activating enzyme 1
chr8_+_15540223 0.98 ENST00000382020.8
ENST00000506802.5
ENST00000503731.6
ENST00000509380.5
tumor suppressor candidate 3
chr6_-_161274010 0.98 ENST00000366911.9
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr2_+_151357583 0.95 ENST00000243347.5
TNF alpha induced protein 6
chr7_+_28685968 0.94 ENST00000396298.6
cAMP responsive element binding protein 5
chr6_-_161274042 0.92 ENST00000320285.9
1-acylglycerol-3-phosphate O-acyltransferase 4
chr9_-_72364504 0.91 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr9_-_122228845 0.91 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr1_-_153549120 0.89 ENST00000368712.1
S100 calcium binding protein A3
chr9_+_135561749 0.89 ENST00000479141.6
ENST00000611414.4
ENST00000371766.6
ENST00000277508.9
ENST00000433563.5
progestagen associated endometrial protein
chr2_+_201257980 0.88 ENST00000447616.5
ENST00000358485.8
ENST00000392266.7
caspase 8
chr20_+_49812818 0.84 ENST00000361573.3
solute carrier family 9 member A8
chr7_+_134843884 0.83 ENST00000445569.6
caldesmon 1
chr16_+_30199860 0.74 ENST00000395138.6
sulfotransferase family 1A member 3
chr7_-_14903319 0.72 ENST00000403951.6
diacylglycerol kinase beta
chr12_+_75391078 0.72 ENST00000550916.6
ENST00000378692.7
ENST00000320460.8
ENST00000547164.1
GLIPR1 like 2
chr11_+_67483019 0.66 ENST00000279146.8
ENST00000528641.7
ENST00000682324.1
ENST00000684006.1
ENST00000683237.1
ENST00000684657.1
aryl hydrocarbon receptor interacting protein
chr17_+_50634845 0.65 ENST00000427699.5
ENST00000285238.13
ATP binding cassette subfamily C member 3
chr22_-_41285868 0.62 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr3_-_11568764 0.58 ENST00000424529.6
vestigial like family member 4
chr1_-_243843164 0.58 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT serine/threonine kinase 3
chr11_-_75490725 0.58 ENST00000529721.5
glycerophosphodiester phosphodiesterase domain containing 5
chr3_+_48465811 0.57 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr1_+_26280117 0.54 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr6_-_149484965 0.53 ENST00000409806.8
zinc finger CCCH-type containing 12D
chr16_-_28597042 0.49 ENST00000533150.5
ENST00000335715.9
sulfotransferase family 1A member 2
chr8_-_109975757 0.43 ENST00000524391.6
potassium voltage-gated channel modifier subfamily V member 1
chr3_+_48466222 0.41 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr11_-_62556230 0.41 ENST00000530285.5
AHNAK nucleoprotein
chr17_+_77450737 0.41 ENST00000541152.6
ENST00000591704.5
septin 9
chr11_-_84317296 0.38 ENST00000280241.12
ENST00000398301.6
discs large MAGUK scaffold protein 2
chr8_-_67062120 0.38 ENST00000357849.9
COP9 signalosome subunit 5
chr5_+_179820895 0.36 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr3_-_9878765 0.31 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
cell death inducing DFFA like effector c
chr5_-_88731827 0.31 ENST00000627170.2
myocyte enhancer factor 2C
chr7_-_135748712 0.28 ENST00000415751.1
family with sequence similarity 180 member A
chr17_+_77319465 0.28 ENST00000329047.13
septin 9
chr12_-_70788914 0.27 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr12_-_7665897 0.23 ENST00000229304.5
apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr10_+_119651372 0.23 ENST00000369085.8
BAG cochaperone 3
chr9_-_107489754 0.16 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr9_-_23826299 0.16 ENST00000380117.5
ELAV like RNA binding protein 2
chr17_+_76385256 0.15 ENST00000392496.3
sphingosine kinase 1
chr1_-_153549238 0.12 ENST00000368713.8
S100 calcium binding protein A3
chr5_-_88785493 0.11 ENST00000503554.4
myocyte enhancer factor 2C
chr2_+_165469647 0.09 ENST00000421875.5
ENST00000314499.11
ENST00000409664.5
ENST00000651982.1
cysteine and serine rich nuclear protein 3
chrX_+_1615158 0.07 ENST00000381229.9
ENST00000381233.8
acetylserotonin O-methyltransferase
chr7_+_1086800 0.07 ENST00000413368.5
ENST00000397092.5
ENST00000297469.3
G protein-coupled estrogen receptor 1
chr10_-_114174183 0.04 ENST00000369285.7
ENST00000369287.8
ENST00000369286.1
ENST00000648613.1
coiled-coil domain containing 186
chr19_+_13731744 0.03 ENST00000586600.5
coiled-coil domain containing 130
chr3_-_9878488 0.00 ENST00000443115.1
cell death inducing DFFA like effector c

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:1902905 positive regulation of fibril organization(GO:1902905)
2.5 9.9 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
2.5 31.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.3 6.9 GO:0046878 positive regulation of saliva secretion(GO:0046878)
2.2 13.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
2.1 6.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
1.1 5.3 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.0 7.8 GO:0010138 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.9 3.5 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.9 3.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.8 33.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.7 2.9 GO:0002384 hepatic immune response(GO:0002384)
0.7 6.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.7 2.0 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.6 2.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.5 4.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.5 7.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 7.7 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 2.6 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.5 6.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.5 1.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.4 5.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 9.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.3 1.0 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.3 1.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 0.9 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.3 2.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 1.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 2.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 10.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 2.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.9 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.2 3.8 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.2 3.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.2 3.3 GO:0001765 membrane raft assembly(GO:0001765)
0.2 2.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 2.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 2.0 GO:0038007 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.2 0.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.6 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.2 1.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.2 0.9 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 1.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 2.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 6.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 1.8 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 5.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.0 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.1 5.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 2.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 2.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 5.3 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 9.3 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 1.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.7 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.6 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 3.6 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 1.4 GO:0043276 anoikis(GO:0043276)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554) DNA cytosine deamination(GO:0070383) regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:1990182 exosomal secretion(GO:1990182)
0.0 2.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.0 GO:0030728 ovulation(GO:0030728)
0.0 2.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.9 GO:0048745 respiratory system process(GO:0003016) smooth muscle tissue development(GO:0048745)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 4.2 GO:0007411 axon guidance(GO:0007411)
0.0 3.3 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 2.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 31.9 GO:0097451 glial limiting end-foot(GO:0097451)
1.3 3.8 GO:0033565 ESCRT-0 complex(GO:0033565)
1.1 6.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 7.9 GO:0097413 Lewy body(GO:0097413)
0.6 2.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 11.5 GO:0036020 endolysosome membrane(GO:0036020)
0.4 2.2 GO:0031673 H zone(GO:0031673)
0.4 9.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 5.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 5.7 GO:0031045 dense core granule(GO:0031045)
0.3 1.0 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 9.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 3.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.7 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 0.6 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.2 1.4 GO:0044294 dendritic growth cone(GO:0044294)
0.2 2.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 7.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 1.2 GO:0097452 GAIT complex(GO:0097452)
0.1 4.9 GO:0042629 mast cell granule(GO:0042629)
0.1 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 10.0 GO:0005604 basement membrane(GO:0005604)
0.1 3.6 GO:0008305 integrin complex(GO:0008305)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 10.6 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 3.1 GO:0031430 M band(GO:0031430)
0.0 0.9 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0044754 autolysosome(GO:0044754)
0.0 6.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 12.0 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 2.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 1.7 GO:0005771 multivesicular body(GO:0005771)
0.0 13.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 2.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 5.4 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 8.4 GO:0005819 spindle(GO:0005819)
0.0 2.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.1 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 11.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
2.0 9.9 GO:1903135 cupric ion binding(GO:1903135)
1.3 6.5 GO:1990254 keratin filament binding(GO:1990254)
1.0 2.9 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.9 3.5 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.9 2.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.7 33.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 2.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 16.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.5 45.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 7.7 GO:0030957 Tat protein binding(GO:0030957)
0.4 1.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.3 2.9 GO:0045545 syndecan binding(GO:0045545)
0.3 9.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 3.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 5.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 2.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.9 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 2.2 GO:0004875 complement receptor activity(GO:0004875)
0.2 0.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 3.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 5.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.9 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 6.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.6 GO:0043495 protein anchor(GO:0043495)
0.1 2.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 7.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 3.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 4.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.8 GO:0070402 NADPH binding(GO:0070402)
0.1 1.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 7.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 4.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 13.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 5.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 10.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.5 PID ARF 3PATHWAY Arf1 pathway
0.4 33.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 16.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 4.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.9 ST STAT3 PATHWAY STAT3 Pathway
0.2 9.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 6.3 PID AURORA B PATHWAY Aurora B signaling
0.1 2.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 6.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 5.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 3.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 4.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 3.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 9.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.7 9.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 11.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 13.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 6.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 30.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 3.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 5.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 8.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 4.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 6.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 5.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 7.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 5.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets