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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for KLF12

Z-value: 1.17

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.18 KLF12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg38_v1_chr13_-_74133892_74133941-0.027.9e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_1762052 14.88 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
SERPINF1
serpin family F member 1
chr9_+_136977496 8.88 ENST00000371625.8
ENST00000457950.5
PTGDS
prostaglandin D2 synthase
chr11_-_62707581 8.06 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr11_-_62707413 8.06 ENST00000360796.10
ENST00000449636.6
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr11_+_117199363 7.67 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
TAGLN
transgelin
chr3_-_123980727 6.14 ENST00000620893.4
ROPN1
rhophilin associated tail protein 1
chr22_+_19131271 5.96 ENST00000399635.4
TSSK2
testis specific serine kinase 2
chr7_+_118224654 4.87 ENST00000265224.9
ENST00000486422.1
ENST00000417525.5
ANKRD7
ankyrin repeat domain 7
chr1_+_153778178 4.27 ENST00000532853.5
SLC27A3
solute carrier family 27 member 3
chr3_+_52420955 4.06 ENST00000465863.1
PHF7
PHD finger protein 7
chr14_+_103334339 4.03 ENST00000558316.5
ENST00000558265.5
EIF5
eukaryotic translation initiation factor 5
chr12_-_55727044 3.72 ENST00000548160.5
CD63
CD63 molecule
chr5_+_138465472 3.68 ENST00000239938.5
EGR1
early growth response 1
chr1_-_202808406 3.57 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
KDM5B
lysine demethylase 5B
chr12_-_7088848 3.53 ENST00000649804.1
C1R
complement C1r
chr17_-_7294592 3.49 ENST00000007699.10
YBX2
Y-box binding protein 2
chr12_+_7060676 3.41 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
C1S
complement C1s
chrX_+_23664251 3.24 ENST00000379349.5
PRDX4
peroxiredoxin 4
chrX_-_72306962 3.14 ENST00000246139.9
CITED1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chrX_-_72307148 3.12 ENST00000453707.6
ENST00000373619.7
CITED1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr1_-_202808464 3.09 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
KDM5B
lysine demethylase 5B
chr1_-_46132650 3.06 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
PIK3R3
phosphoinositide-3-kinase regulatory subunit 3
chr2_-_219571241 2.98 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
OBSL1
obscurin like cytoskeletal adaptor 1
chr12_-_55727080 2.87 ENST00000548898.5
ENST00000552067.5
CD63
CD63 molecule
chr4_-_74099187 2.77 ENST00000508487.3
CXCL2
C-X-C motif chemokine ligand 2
chr6_+_27147094 2.52 ENST00000377459.3
H2AC12
H2A clustered histone 12
chr1_-_46132616 2.52 ENST00000423209.5
ENST00000262741.10
PIK3R3
phosphoinositide-3-kinase regulatory subunit 3
chr4_+_127781815 2.41 ENST00000508776.5
HSPA4L
heat shock protein family A (Hsp70) member 4 like
chr15_+_73926443 2.31 ENST00000261921.8
LOXL1
lysyl oxidase like 1
chr17_+_42853232 2.24 ENST00000617500.4
AOC3
amine oxidase copper containing 3
chr17_+_20155989 2.13 ENST00000395530.6
ENST00000581399.6
ENST00000679819.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_-_43022350 2.02 ENST00000587173.5
ENST00000355653.8
VAT1
vesicle amine transport 1
chr3_-_49685090 2.01 ENST00000448220.5
MST1
macrophage stimulating 1
chr20_-_40689228 2.01 ENST00000373313.3
MAFB
MAF bZIP transcription factor B
chr6_+_31927683 1.91 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr11_-_102530738 1.90 ENST00000260227.5
MMP7
matrix metallopeptidase 7
chr17_+_18039370 1.88 ENST00000268719.9
ENST00000376345.3
GID4
GID complex subunit 4 homolog
chr3_+_49021071 1.84 ENST00000395458.6
NDUFAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr17_+_7307531 1.83 ENST00000576930.5
EIF5A
eukaryotic translation initiation factor 5A
chr2_+_90159840 1.82 ENST00000377032.5
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr19_-_51024211 1.75 ENST00000593681.5
KLK11
kallikrein related peptidase 11
chr3_+_148791058 1.72 ENST00000491148.5
CPB1
carboxypeptidase B1
chr4_+_127782270 1.68 ENST00000508549.5
ENST00000296464.9
HSPA4L
heat shock protein family A (Hsp70) member 4 like
chr12_+_120469819 1.67 ENST00000392509.6
ENST00000549649.5
ENST00000548342.5
DYNLL1
dynein light chain LC8-type 1
chr16_+_67326808 1.65 ENST00000329956.11
ENST00000569499.6
ENST00000561948.1
LRRC36
leucine rich repeat containing 36
chr3_-_133895753 1.64 ENST00000460865.3
RAB6B
RAB6B, member RAS oncogene family
chr9_+_137742957 1.62 ENST00000637318.1
ENST00000478940.1
EHMT1
euchromatic histone lysine methyltransferase 1
chr11_-_32435529 1.61 ENST00000448076.9
ENST00000452863.10
WT1
WT1 transcription factor
chr17_+_7307602 1.60 ENST00000573542.5
ENST00000336458.13
EIF5A
eukaryotic translation initiation factor 5A
chr17_+_7307961 1.59 ENST00000419711.6
ENST00000571955.5
ENST00000573714.5
EIF5A
eukaryotic translation initiation factor 5A
chr14_-_105708627 1.58 ENST00000641837.1
ENST00000390547.3
IGHA1
immunoglobulin heavy constant alpha 1
chr9_-_89178810 1.57 ENST00000375835.9
SHC3
SHC adaptor protein 3
chr12_-_123972824 1.56 ENST00000238156.8
ENST00000545037.1
CCDC92
coiled-coil domain containing 92
chr2_-_38377256 1.55 ENST00000443098.5
ENST00000449130.5
ENST00000651368.1
ENST00000378954.9
ENST00000419554.6
ENST00000451483.1
ENST00000406122.5
ATL2
atlastin GTPase 2
chr3_+_194136138 1.55 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr6_+_19837362 1.51 ENST00000378700.8
ID4
inhibitor of DNA binding 4, HLH protein
chr2_-_55296361 1.50 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr12_-_123972709 1.50 ENST00000545891.5
CCDC92
coiled-coil domain containing 92
chr6_-_134318097 1.48 ENST00000367858.10
ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr20_-_17659917 1.47 ENST00000610403.4
RRBP1
ribosome binding protein 1
chr6_+_31927703 1.46 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
C2
ENSG00000244255.5
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr14_-_91946989 1.41 ENST00000556154.5
FBLN5
fibulin 5
chr12_-_55728339 1.41 ENST00000552754.5
CD63
CD63 molecule
chr16_-_1230089 1.41 ENST00000612142.1
ENST00000606293.5
TPSB2
tryptase beta 2
chr6_+_22569554 1.38 ENST00000510882.4
HDGFL1
HDGF like 1
chr14_-_106737547 1.35 ENST00000632209.1
IGHV1-69-2
immunoglobulin heavy variable 1-69-2
chr16_+_75222609 1.34 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr2_+_90100235 1.33 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr19_-_4338786 1.32 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
STAP2
signal transducing adaptor family member 2
chr12_-_55728436 1.32 ENST00000552692.5
CD63
CD63 molecule
chr12_+_53454819 1.31 ENST00000562264.5
PCBP2
poly(rC) binding protein 2
chr14_+_103715724 1.30 ENST00000216602.10
ZFYVE21
zinc finger FYVE-type containing 21
chr10_-_79445617 1.28 ENST00000372336.4
ZCCHC24
zinc finger CCHC-type containing 24
chr4_+_73869385 1.26 ENST00000395761.4
CXCL1
C-X-C motif chemokine ligand 1
chr14_+_103715767 1.25 ENST00000311141.7
ZFYVE21
zinc finger FYVE-type containing 21
chr2_+_104854104 1.23 ENST00000361360.4
POU3F3
POU class 3 homeobox 3
chr17_+_7307579 1.23 ENST00000572815.5
EIF5A
eukaryotic translation initiation factor 5A
chr8_+_140511286 1.23 ENST00000519533.1
ENST00000220913.10
CHRAC1
chromatin accessibility complex subunit 1
chr17_-_8630713 1.22 ENST00000411957.1
ENST00000360416.8
MYH10
myosin heavy chain 10
chr18_+_58864866 1.19 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr1_-_153628180 1.19 ENST00000339556.8
ENST00000440685.7
S100A13
S100 calcium binding protein A13
chr12_-_120469571 1.18 ENST00000550458.1
SRSF9
serine and arginine rich splicing factor 9
chr22_-_31346317 1.17 ENST00000266269.10
PATZ1
POZ/BTB and AT hook containing zinc finger 1
chr1_+_27234612 1.17 ENST00000319394.8
ENST00000361771.7
WDTC1
WD and tetratricopeptide repeats 1
chr19_+_54137740 1.17 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CNOT3
CCR4-NOT transcription complex subunit 3
chr11_+_307915 1.16 ENST00000616316.2
IFITM2
interferon induced transmembrane protein 2
chr17_-_8630749 1.15 ENST00000379980.8
ENST00000269243.8
MYH10
myosin heavy chain 10
chr2_-_110534010 1.15 ENST00000437167.1
RGPD6
RANBP2 like and GRIP domain containing 6
chr11_-_32435360 1.14 ENST00000639563.3
WT1
WT1 transcription factor
chr1_+_50108856 1.13 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAVL4
ELAV like RNA binding protein 4
chr12_+_57089094 1.13 ENST00000342556.6
ENST00000300131.8
NAB2
NGFI-A binding protein 2
chr19_+_17719471 1.12 ENST00000600186.5
ENST00000597735.5
ENST00000324096.9
MAP1S
microtubule associated protein 1S
chr6_+_11537738 1.12 ENST00000379426.2
TMEM170B
transmembrane protein 170B
chr1_-_155207886 1.11 ENST00000368378.7
ENST00000541990.5
ENST00000457183.6
ENST00000541576.5
THBS3
thrombospondin 3
chrX_-_11665908 1.10 ENST00000337414.9
ARHGAP6
Rho GTPase activating protein 6
chr8_+_96493803 1.10 ENST00000518385.5
ENST00000302190.9
SDC2
syndecan 2
chr20_-_17660439 1.10 ENST00000246043.8
RRBP1
ribosome binding protein 1
chr12_-_52618559 1.09 ENST00000305748.7
KRT73
keratin 73
chr15_-_34101807 1.09 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
EMC7
ER membrane protein complex subunit 7
chr22_-_38302990 1.08 ENST00000612795.2
ENST00000451964.5
CSNK1E
casein kinase 1 epsilon
chr18_-_55585773 1.07 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
TCF4
transcription factor 4
chr9_-_96302104 1.06 ENST00000375262.4
ENST00000650386.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr9_-_96302170 1.06 ENST00000375263.8
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr19_-_55354703 1.06 ENST00000593184.5
ENST00000326529.9
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit 6B2
chr1_+_109249530 1.05 ENST00000271332.4
CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
chr7_+_94908230 1.05 ENST00000433881.5
PPP1R9A
protein phosphatase 1 regulatory subunit 9A
chr16_-_67481079 1.05 ENST00000565835.5
ENST00000602876.5
ENST00000540149.5
ATP6V0D1
ATPase H+ transporting V0 subunit d1
chr10_+_45972482 1.03 ENST00000580018.4
TIMM23
translocase of inner mitochondrial membrane 23
chr12_-_23584600 1.03 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr7_+_107580215 1.02 ENST00000465919.5
ENST00000005259.9
ENST00000445771.6
ENST00000479917.5
ENST00000421217.5
ENST00000457837.5
BCAP29
B cell receptor associated protein 29
chr16_-_19886133 1.02 ENST00000568214.1
ENST00000569479.5
GPRC5B
G protein-coupled receptor class C group 5 member B
chr1_+_155127866 1.02 ENST00000368406.2
ENST00000368407.8
EFNA1
ephrin A1
chr2_-_27370300 1.02 ENST00000622434.4
ENST00000493344.6
ENST00000445933.6
ENST00000347454.9
EIF2B4
eukaryotic translation initiation factor 2B subunit delta
chr14_-_105588322 1.01 ENST00000497872.4
ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr10_+_49942048 1.00 ENST00000651259.3
ENST00000652716.1
TIMM23B
translocase of inner mitochondrial membrane 23 homolog B
chr7_+_107580454 1.00 ENST00000379117.6
ENST00000473124.1
BCAP29
B cell receptor associated protein 29
chr1_-_6180265 0.99 ENST00000262450.8
CHD5
chromodomain helicase DNA binding protein 5
chr12_-_55727796 0.99 ENST00000550776.5
CD63
CD63 molecule
chrX_+_154429092 0.98 ENST00000619046.5
ATP6AP1
ATPase H+ transporting accessory protein 1
chr12_-_120469655 0.98 ENST00000229390.8
SRSF9
serine and arginine rich splicing factor 9
chr2_-_219543793 0.97 ENST00000243776.11
CHPF
chondroitin polymerizing factor
chr18_-_34224871 0.96 ENST00000261592.10
NOL4
nucleolar protein 4
chr1_+_154220849 0.95 ENST00000613315.4
ENST00000271877.11
ENST00000441890.5
ENST00000412596.5
ENST00000368504.5
ENST00000428931.6
ENST00000437652.5
UBAP2L
ubiquitin associated protein 2 like
chr17_+_28744002 0.95 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TRAF4
TNF receptor associated factor 4
chr15_+_41493860 0.95 ENST00000260386.7
ITPKA
inositol-trisphosphate 3-kinase A
chr9_-_96302142 0.94 ENST00000648799.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr17_+_28744034 0.93 ENST00000444415.7
ENST00000262396.10
TRAF4
TNF receptor associated factor 4
chr11_-_125496122 0.93 ENST00000527534.1
ENST00000278919.8
ENST00000366139.3
FEZ1
fasciculation and elongation protein zeta 1
chr22_+_22792485 0.92 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr21_-_37072997 0.91 ENST00000430792.1
ENST00000399103.5
PIGP
phosphatidylinositol glycan anchor biosynthesis class P
chr8_+_7847870 0.91 ENST00000400125.6
ENST00000434307.6
ENST00000642566.1
SPAG11A
sperm associated antigen 11A
chr16_-_67481131 0.91 ENST00000290949.8
ATP6V0D1
ATPase H+ transporting V0 subunit d1
chr4_+_3441960 0.90 ENST00000382774.8
ENST00000511533.1
HGFAC
HGF activator
chr1_+_156114700 0.89 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
LMNA
lamin A/C
chr6_+_33200820 0.85 ENST00000374675.7
SLC39A7
solute carrier family 39 member 7
chr9_-_128322407 0.85 ENST00000372890.6
TRUB2
TruB pseudouridine synthase family member 2
chr7_+_142750657 0.85 ENST00000492062.1
PRSS1
serine protease 1
chr2_+_230878139 0.84 ENST00000620962.1
ITM2C
integral membrane protein 2C
chr17_+_8288637 0.84 ENST00000407006.8
ENST00000226105.11
ENST00000580434.5
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr2_-_27370419 0.84 ENST00000616081.4
EIF2B4
eukaryotic translation initiation factor 2B subunit delta
chr20_-_35699317 0.83 ENST00000397425.5
ENST00000374092.9
ENST00000541387.5
NFS1
NFS1 cysteine desulfurase
chr11_-_120138104 0.83 ENST00000341846.10
TRIM29
tripartite motif containing 29
chrX_+_54809060 0.81 ENST00000396224.1
MAGED2
MAGE family member D2
chr1_+_50109817 0.80 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAVL4
ELAV like RNA binding protein 4
chr1_-_42740140 0.80 ENST00000372539.3
ENST00000296387.6
ENST00000539749.5
CLDN19
claudin 19
chr14_+_85530127 0.80 ENST00000330753.6
FLRT2
fibronectin leucine rich transmembrane protein 2
chr18_+_22169580 0.80 ENST00000269216.10
GATA6
GATA binding protein 6
chr10_-_50885656 0.79 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr15_+_34102037 0.79 ENST00000397766.4
PGBD4
piggyBac transposable element derived 4
chr19_-_45768627 0.78 ENST00000560160.1
SIX5
SIX homeobox 5
chr6_-_34696733 0.77 ENST00000374023.8
ILRUN
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr1_+_50109788 0.77 ENST00000651258.1
ELAVL4
ELAV like RNA binding protein 4
chr1_+_50109620 0.77 ENST00000371819.1
ELAVL4
ELAV like RNA binding protein 4
chr6_-_27146841 0.76 ENST00000356950.2
H2BC12
H2B clustered histone 12
chr19_-_18606779 0.76 ENST00000684169.1
ENST00000392386.8
CRLF1
cytokine receptor like factor 1
chr5_-_128538230 0.75 ENST00000262464.9
FBN2
fibrillin 2
chr5_+_176365455 0.75 ENST00000310389.6
ARL10
ADP ribosylation factor like GTPase 10
chr3_-_155806260 0.75 ENST00000534941.2
ENST00000340171.7
C3orf33
chromosome 3 open reading frame 33
chr2_+_24049673 0.74 ENST00000380991.8
FKBP1B
FKBP prolyl isomerase 1B
chr1_+_179743163 0.74 ENST00000341785.4
FAM163A
family with sequence similarity 163 member A
chr8_-_7463452 0.73 ENST00000528943.5
ENST00000359758.9
ENST00000361111.6
ENST00000398462.7
ENST00000297498.6
ENST00000317900.7
SPAG11B
sperm associated antigen 11B
chr1_+_23791203 0.73 ENST00000374503.7
ENST00000374502.7
LYPLA2
lysophospholipase 2
chr12_-_56488153 0.73 ENST00000311966.9
GLS2
glutaminase 2
chr2_+_27370496 0.72 ENST00000537606.5
ENST00000233575.7
SNX17
sorting nexin 17
chr8_-_30812867 0.72 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr4_-_74038681 0.72 ENST00000296026.4
CXCL3
C-X-C motif chemokine ligand 3
chr14_+_75428011 0.72 ENST00000651602.1
ENST00000559060.5
JDP2
Jun dimerization protein 2
chr14_-_53153098 0.72 ENST00000612692.4
ENST00000395606.5
DDHD1
DDHD domain containing 1
chr1_+_226548747 0.72 ENST00000366788.8
ENST00000366789.5
STUM
stum, mechanosensory transduction mediator homolog
chr13_-_67230377 0.71 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr2_+_89913982 0.71 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr17_-_39401593 0.70 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
FBXL20
F-box and leucine rich repeat protein 20
chr2_+_24049705 0.70 ENST00000380986.9
ENST00000452109.1
FKBP1B
FKBP prolyl isomerase 1B
chr1_+_155208727 0.70 ENST00000316721.8
MTX1
metaxin 1
chr14_+_24368020 0.69 ENST00000554050.5
ENST00000554903.1
ENST00000250373.9
ENST00000554779.1
ENST00000553708.5
NFATC4
nuclear factor of activated T cells 4
chr11_+_65386611 0.69 ENST00000531296.1
ENST00000533782.5
ENST00000355991.9
ENST00000317568.10
ENST00000416776.6
ENST00000526201.1
FRMD8
FERM domain containing 8
chr1_+_213987929 0.69 ENST00000498508.6
ENST00000366958.9
PROX1
prospero homeobox 1
chr1_-_18902520 0.69 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
ALDH4A1
aldehyde dehydrogenase 4 family member A1
chr19_-_55175031 0.69 ENST00000587067.1
SYT5
synaptotagmin 5
chr6_-_41895359 0.68 ENST00000373006.5
ENST00000682992.1
USP49
ubiquitin specific peptidase 49
chr14_-_53153281 0.67 ENST00000357758.3
ENST00000673822.2
DDHD1
DDHD domain containing 1
chr3_-_49021045 0.67 ENST00000440857.5
DALRD3
DALR anticodon binding domain containing 3
chr2_+_188291661 0.67 ENST00000409843.5
GULP1
GULP PTB domain containing engulfment adaptor 1
chr12_-_56488350 0.67 ENST00000623608.3
ENST00000610413.4
GLS2
glutaminase 2
chr6_+_33200860 0.67 ENST00000374677.8
SLC39A7
solute carrier family 39 member 7
chr22_+_24806265 0.66 ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr11_-_66593031 0.66 ENST00000333861.5
CCDC87
coiled-coil domain containing 87
chr15_-_65067938 0.66 ENST00000421977.7
ENST00000220062.9
RASL12
RAS like family 12
chr16_+_30664334 0.66 ENST00000287468.5
FBRS
fibrosin
chr20_-_33720221 0.65 ENST00000409299.8
ENST00000217398.3
ENST00000344022.7
PXMP4
peroxisomal membrane protein 4
chr12_+_72272360 0.64 ENST00000547300.2
ENST00000261180.10
TRHDE
thyrotropin releasing hormone degrading enzyme
chr4_+_77605807 0.64 ENST00000682537.1
CXCL13
C-X-C motif chemokine ligand 13
chr17_-_40822604 0.64 ENST00000269576.6
ENST00000635956.2
KRT10
keratin 10
chr3_-_100114488 0.63 ENST00000477258.2
ENST00000354552.7
ENST00000331335.9
ENST00000398326.2
FILIP1L
filamin A interacting protein 1 like
chr11_+_7513966 0.63 ENST00000299492.9
PPFIBP2
PPFIA binding protein 2
chr14_+_73950489 0.63 ENST00000554320.1
COQ6
coenzyme Q6, monooxygenase
chr21_-_37072688 0.61 ENST00000464265.5
ENST00000399102.5
PIGP
phosphatidylinositol glycan anchor biosynthesis class P
chr2_+_89862438 0.61 ENST00000448155.2
IGKV1D-39
immunoglobulin kappa variable 1D-39
chr10_-_50885619 0.60 ENST00000373997.8
A1CF
APOBEC1 complementation factor
chrX_-_45200895 0.59 ENST00000377934.4
DIPK2B
divergent protein kinase domain 2B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 14.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
1.3 6.5 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
1.3 6.4 GO:0072301 regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
1.2 3.5 GO:0009386 translational attenuation(GO:0009386)
1.0 6.3 GO:0071105 response to interleukin-11(GO:0071105)
0.8 3.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.8 16.1 GO:0034389 lipid particle organization(GO:0034389)
0.8 2.4 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.8 6.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8 1.5 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.7 10.3 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.6 2.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.5 1.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.5 2.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.5 2.0 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 8.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 1.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 2.8 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.4 4.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 1.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 2.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 2.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 2.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 0.8 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.3 0.8 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.3 0.8 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.3 0.5 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.3 1.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 3.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.9 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.2 1.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 1.6 GO:0060992 response to fungicide(GO:0060992)
0.2 1.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 0.8 GO:0031627 telomeric loop formation(GO:0031627)
0.2 1.7 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.1 GO:0008218 bioluminescence(GO:0008218)
0.2 5.6 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 2.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 1.0 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.1 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.2 0.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 0.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.9 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 2.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 3.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.9 GO:0060346 bone trabecula formation(GO:0060346)
0.1 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.4 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 2.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.6 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.8 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 1.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.3 GO:0090427 egg activation(GO:0007343) activation of meiosis(GO:0090427)
0.1 2.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.4 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.1 0.4 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 2.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.6 GO:0098722 asymmetric stem cell division(GO:0098722)
0.1 2.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 9.2 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.3 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.1 0.1 GO:1905064 negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1 0.5 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 1.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 1.6 GO:0044849 estrous cycle(GO:0044849)
0.1 1.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.5 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.1 1.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.5 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1 0.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 1.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 5.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 2.3 GO:0035904 aorta development(GO:0035904)
0.0 1.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0048664 neuron fate determination(GO:0048664)
0.0 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.7 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 4.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.7 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 1.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0086043 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 4.1 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.1 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0003360 brainstem development(GO:0003360)
0.0 1.4 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 3.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 1.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.7 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 1.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.5 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.0 1.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0048515 spermatid differentiation(GO:0048515)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.6 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 14.9 GO:0043203 axon hillock(GO:0043203)
0.9 2.6 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.9 10.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 2.8 GO:1990393 3M complex(GO:1990393)
0.5 2.4 GO:0097513 myosin II filament(GO:0097513)
0.4 6.2 GO:0005642 annulate lamellae(GO:0005642)
0.3 1.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 1.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 2.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 4.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.4 GO:0071953 elastic fiber(GO:0071953)
0.2 2.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 1.1 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.0 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.7 GO:1990769 proximal neuron projection(GO:1990769)
0.1 19.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 9.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 3.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.4 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.1 0.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 8.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 10.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 4.6 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 3.6 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.0 GO:0014802 terminal cisterna(GO:0014802)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 5.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.3 6.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
1.3 6.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.7 4.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.6 5.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.6 2.2 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.4 3.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.4 2.5 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.4 6.8 GO:0050693 LBD domain binding(GO:0050693)
0.4 3.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 2.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 5.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 6.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 2.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 4.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 2.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.4 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 2.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 1.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 0.5 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 15.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 3.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 4.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 25.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.3 GO:0004079 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.5 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.8 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0003696 satellite DNA binding(GO:0003696)
0.1 1.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 2.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.0 GO:0048185 activin binding(GO:0048185)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 6.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.9 GO:0004620 phospholipase activity(GO:0004620)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 4.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 21.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.6 PID FOXO PATHWAY FoxO family signaling
0.0 6.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 5.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 1.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 6.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 4.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 8.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction