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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for KLF15
Z-value: 0.28
Motif logo
Transcription factors associated with KLF15
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
KLF15
|
ENSG00000163884.4 | KLF15 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF15 | hg38_v1_chr3_-_126357399_126357414 | 0.02 | 8.2e-01 | Click! |
Activity profile of KLF15 motif
Sorted Z-values of KLF15 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF15
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 16.2 | GO:2001076 | regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
| 2.6 | 7.8 | GO:1904692 | positive regulation of type B pancreatic cell proliferation(GO:1904692) |
| 1.9 | 5.6 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 1.6 | 4.8 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 1.6 | 4.8 | GO:1905053 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 1.3 | 3.9 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 1.3 | 3.9 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662) |
| 1.2 | 11.1 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 1.1 | 3.2 | GO:0009183 | ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 1.0 | 4.0 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.9 | 2.6 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.8 | 13.2 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.7 | 3.7 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.7 | 2.1 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.6 | 2.5 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 0.6 | 7.3 | GO:1990416 | synaptic vesicle uncoating(GO:0016191) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.5 | 1.6 | GO:0060995 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.5 | 2.1 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 0.5 | 2.6 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.5 | 1.5 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.5 | 8.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.5 | 2.9 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.5 | 7.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.4 | 8.4 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.4 | 3.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.4 | 2.9 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.4 | 1.2 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.4 | 2.4 | GO:0003011 | involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.4 | 4.3 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.4 | 3.6 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.3 | 1.0 | GO:0060032 | notochord regression(GO:0060032) |
| 0.3 | 1.4 | GO:0006288 | base-excision repair, DNA ligation(GO:0006288) |
| 0.3 | 1.4 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.3 | 1.4 | GO:1902530 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 0.3 | 2.0 | GO:0034436 | glycoprotein transport(GO:0034436) |
| 0.3 | 3.0 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.3 | 1.3 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.3 | 1.8 | GO:0048619 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
| 0.3 | 2.8 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.3 | 0.9 | GO:1902263 | atrioventricular node development(GO:0003162) cardiac right atrium morphogenesis(GO:0003213) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 0.3 | 3.0 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.3 | 3.7 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.3 | 1.4 | GO:2000542 | negative regulation of gastrulation(GO:2000542) |
| 0.3 | 1.4 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.3 | 2.3 | GO:0032776 | DNA methylation on cytosine(GO:0032776) |
| 0.3 | 4.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.2 | 1.7 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.2 | 0.5 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.2 | 0.7 | GO:2000740 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 0.2 | 13.3 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.2 | 0.9 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 0.2 | 4.0 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.2 | 0.9 | GO:0010728 | regulation of hydrogen peroxide biosynthetic process(GO:0010728) |
| 0.2 | 2.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.2 | 3.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 3.2 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.2 | 1.2 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 1.1 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.2 | 1.3 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.2 | 1.6 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.2 | 0.4 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.2 | 1.0 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.2 | 0.5 | GO:0046959 | habituation(GO:0046959) |
| 0.2 | 0.5 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.2 | 0.5 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 0.2 | 4.8 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.2 | 1.7 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.2 | 5.7 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.2 | 1.5 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 6.5 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
| 0.2 | 3.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.2 | 1.1 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.2 | 0.6 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
| 0.1 | 3.4 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.1 | 1.3 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 0.1 | 0.6 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 0.1 | 0.3 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.1 | 0.7 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.1 | 2.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 1.4 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 6.8 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 9.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 0.3 | GO:1901376 | mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376) |
| 0.1 | 0.8 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.1 | 0.7 | GO:1990164 | histone H2A phosphorylation(GO:1990164) |
| 0.1 | 2.2 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 1.0 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 4.2 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.1 | 3.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 2.8 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
| 0.1 | 0.5 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.1 | 0.6 | GO:1904693 | midbrain morphogenesis(GO:1904693) |
| 0.1 | 3.8 | GO:0071711 | basement membrane organization(GO:0071711) |
| 0.1 | 1.4 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.1 | 0.9 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.1 | 2.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 1.0 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.1 | 1.6 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.1 | 5.0 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.1 | 2.3 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.1 | 0.4 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.1 | 0.5 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 0.1 | 0.4 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.1 | 3.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 1.3 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.1 | 0.3 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.1 | 2.4 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.1 | 0.3 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 1.4 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.6 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 2.6 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.1 | 1.7 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.1 | 1.6 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 0.2 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.1 | 0.3 | GO:1903238 | positive regulation of leukocyte tethering or rolling(GO:1903238) |
| 0.1 | 1.7 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.1 | 0.5 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.1 | 1.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.5 | GO:1902748 | melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.1 | 1.1 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.1 | 0.7 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.1 | 0.5 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.0 | 0.6 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.7 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.1 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.0 | 1.8 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.2 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.0 | 4.2 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
| 0.0 | 0.8 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.2 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.5 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.0 | 10.7 | GO:0006457 | protein folding(GO:0006457) |
| 0.0 | 0.4 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.0 | 0.8 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 2.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 5.5 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.0 | 0.2 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.0 | 3.1 | GO:0005977 | glycogen metabolic process(GO:0005977) |
| 0.0 | 1.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.5 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.6 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 2.1 | GO:1902400 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
| 0.0 | 0.3 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.0 | 0.4 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.0 | 2.1 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 1.2 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.7 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.0 | 0.3 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.0 | 0.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 1.0 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.4 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.4 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 0.9 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.0 | 0.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.0 | 0.1 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.0 | 0.1 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 0.1 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.0 | 2.7 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.2 | GO:1902415 | regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) |
| 0.0 | 0.1 | GO:0046465 | dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465) |
| 0.0 | 0.3 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.2 | GO:0007379 | segment specification(GO:0007379) |
| 0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.7 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.0 | 0.8 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.0 | 0.5 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.4 | GO:0043949 | regulation of cAMP-mediated signaling(GO:0043949) |
| 0.0 | 0.2 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.5 | GO:0016574 | histone ubiquitination(GO:0016574) |
| 0.0 | 0.6 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 0.1 | GO:0036493 | positive regulation of translation in response to stress(GO:0032056) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.5 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.5 | 3.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.5 | 1.4 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 23.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.4 | 1.8 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.4 | 4.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.3 | 1.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.3 | 1.7 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.3 | 19.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.3 | 1.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.3 | 4.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.2 | 10.3 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.2 | 3.1 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 1.5 | GO:0016589 | NURF complex(GO:0016589) |
| 0.2 | 3.7 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.2 | 3.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.6 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 2.6 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 0.6 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.1 | 5.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 1.0 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 1.3 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 8.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 0.9 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.1 | 15.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 6.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 3.2 | GO:0043218 | compact myelin(GO:0043218) |
| 0.1 | 0.5 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 1.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 3.0 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 3.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 0.7 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 1.0 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 5.5 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 5.9 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.4 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.1 | 4.2 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 1.7 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.1 | 3.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 8.1 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.1 | 1.8 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 0.8 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 0.2 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 1.7 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 2.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 0.6 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 3.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 0.8 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 0.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.5 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.8 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 13.0 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 0.6 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 4.2 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 2.9 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 5.1 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.2 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.0 | 3.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.6 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.0 | 0.1 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.0 | 2.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 1.0 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 1.9 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 2.5 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 3.5 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.4 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 7.6 | GO:0005929 | cilium(GO:0005929) |
| 0.0 | 0.8 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 5.0 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 0.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 1.3 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 1.2 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 2.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.3 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 1.5 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 1.7 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 5.7 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 2.0 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 7.5 | GO:0005694 | chromosome(GO:0005694) |
| 0.0 | 0.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 3.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 1.4 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 6.3 | GO:0015630 | microtubule cytoskeleton(GO:0015630) |
| 0.0 | 0.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.9 | 11.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.8 | 16.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.7 | 6.7 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.7 | 2.0 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.6 | 5.6 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.6 | 2.5 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.5 | 8.0 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.5 | 3.0 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.5 | 4.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.5 | 2.9 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.4 | 1.8 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.4 | 4.0 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.4 | 5.7 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.3 | 2.8 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.3 | 1.6 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.3 | 2.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.3 | 10.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.3 | 4.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.3 | 3.7 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.3 | 2.6 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.3 | 0.8 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.2 | 17.2 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.2 | 3.9 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.2 | 2.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.2 | 3.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.2 | 4.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 0.9 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 0.2 | 0.7 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 0.2 | 9.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.2 | 0.5 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 0.2 | 0.5 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.2 | 4.8 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.2 | 0.6 | GO:0004487 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 0.2 | 4.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 4.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 1.7 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 1.7 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 3.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 3.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.5 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 3.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 3.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 2.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 3.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 7.2 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 0.6 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 1.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.3 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.1 | 1.0 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 2.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 2.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 9.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 2.9 | GO:0035591 | signaling adaptor activity(GO:0035591) |
| 0.1 | 0.6 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 1.3 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 1.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 2.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.3 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.1 | 3.4 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 0.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 2.1 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 8.2 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 1.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 3.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 0.6 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 1.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 20.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 1.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.1 | 0.8 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.2 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.1 | 2.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 0.3 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 1.8 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 1.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 3.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.3 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.7 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 0.7 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 1.4 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 1.5 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.9 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.8 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 5.9 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 3.5 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.3 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.0 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 2.3 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 2.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 3.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 3.0 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 1.1 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.7 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.7 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.2 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.0 | 1.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.4 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.1 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 0.1 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.0 | 0.7 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.1 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
| 0.0 | 0.3 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.2 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 4.8 | GO:0016887 | ATPase activity(GO:0016887) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 10.2 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.3 | 16.2 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.2 | 5.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.2 | 12.2 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 5.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 12.0 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 2.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 3.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 3.4 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 3.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 1.6 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.1 | 1.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 2.4 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 1.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 1.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 2.1 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 0.8 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.6 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 1.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 3.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.4 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 8.1 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.5 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 2.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.8 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.4 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.4 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 1.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.2 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 0.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.1 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 7.5 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.4 | 13.2 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.3 | 7.3 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.2 | 2.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.2 | 9.8 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.2 | 2.5 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.2 | 5.9 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 2.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.2 | 13.5 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 1.4 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 2.2 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.7 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.1 | 16.9 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 3.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 4.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 5.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 1.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 2.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 16.0 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 2.1 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.6 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 1.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.1 | 1.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 2.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 1.5 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 1.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 1.7 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 0.0 | 1.4 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.1 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.9 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 0.0 | 0.6 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 1.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.7 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.4 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.5 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 0.4 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.8 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 1.8 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 1.4 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.2 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.1 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |