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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for KLF8

Z-value: 12.82

Motif logo

Transcription factors associated with KLF8

Gene Symbol Gene ID Gene Info
ENSG00000102349.18 KLF8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF8hg38_v1_chrX_+_56232343_562323630.661.5e-28Click!

Activity profile of KLF8 motif

Sorted Z-values of KLF8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_105771405 42.74 ENST00000641136.1
ENST00000390551.6
immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_+_33080445 31.01 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr16_+_176659 28.15 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr15_+_68930488 26.35 ENST00000310673.4
ENST00000448182.7
ENST00000260364.9
sperm equatorial segment protein 1
NADPH oxidase 5
chr6_-_33080710 25.42 ENST00000419277.5
major histocompatibility complex, class II, DP alpha 1
chr22_-_39152622 23.39 ENST00000216133.10
chromobox 7
chr8_-_27611325 23.38 ENST00000523500.5
clusterin
chr16_+_172869 22.52 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr6_+_31897775 21.68 ENST00000469372.5
ENST00000497706.5
complement C2
chr15_+_68930570 21.58 ENST00000455873.7
NADPH oxidase 5
chr3_+_10164883 21.54 ENST00000256458.5
interleukin 1 receptor associated kinase 2
chr19_+_16197900 20.90 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
adaptor related protein complex 1 subunit mu 1
chr5_+_151020438 20.70 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
glutathione peroxidase 3
chr20_+_59933761 20.54 ENST00000358293.7
family with sequence similarity 217 member B
chr9_-_90642855 20.44 ENST00000637905.1
DIRAS family GTPase 2
chr17_-_42050587 20.33 ENST00000587304.3
chromosome 17 open reading frame 113
chr22_+_22357739 20.23 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr17_+_39927724 19.78 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr19_+_55675191 19.33 ENST00000270460.11
ENST00000085079.11
epsin 1
chr16_+_58249910 18.97 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr17_+_1762052 18.75 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
serpin family F member 1
chr22_+_22895368 18.69 ENST00000390321.2
immunoglobulin lambda constant 1
chr4_+_186191549 18.25 ENST00000378802.5
cytochrome P450 family 4 subfamily V member 2
chr2_+_238138661 18.13 ENST00000409223.2
kelch like family member 30
chr10_+_38010617 18.09 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr1_-_1574551 17.96 ENST00000359060.5
SSU72 homolog, RNA polymerase II CTD phosphatase
chr5_+_134905100 17.78 ENST00000512783.5
ENST00000254908.11
pterin-4 alpha-carbinolamine dehydratase 2
chr22_+_22431949 17.74 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr22_+_22887780 17.69 ENST00000532223.2
ENST00000526893.6
ENST00000531372.1
immunoglobulin lambda like polypeptide 5
chr1_+_22636577 17.13 ENST00000374642.8
ENST00000438241.1
complement C1q A chain
chr6_+_42879610 16.99 ENST00000493763.7
ENST00000304734.9
ribosomal protein L7 like 1
chr9_+_136979042 16.88 ENST00000446677.2
prostaglandin D2 synthase
chr12_-_91179355 16.83 ENST00000550563.5
ENST00000546370.5
decorin
chr9_+_136980211 16.75 ENST00000444903.2
prostaglandin D2 synthase
chr3_-_155806260 16.71 ENST00000534941.2
ENST00000340171.7
chromosome 3 open reading frame 33
chr19_-_52690533 16.50 ENST00000598322.2
novel zinc finger protein
chr14_-_105626066 16.00 ENST00000641978.1
ENST00000390543.3
immunoglobulin heavy constant gamma 4 (G4m marker)
chr5_-_140564550 15.77 ENST00000357560.9
ENST00000358580.9
amyloid beta precursor protein binding family B member 3
chr20_+_23035312 15.63 ENST00000255008.5
somatostatin receptor 4
chr22_+_50481515 15.63 ENST00000395737.2
ENST00000395738.2
adrenomedullin 2
chr19_-_8832286 15.57 ENST00000601372.6
zinc finger protein 558
chr14_-_105743032 15.56 ENST00000390548.6
ENST00000390549.6
ENST00000390542.6
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_+_56404314 15.46 ENST00000333201.13
ENST00000391778.3
zinc finger protein 583
chr16_+_4734519 15.44 ENST00000299320.10
chromosome 16 open reading frame 71
chr8_-_27611424 15.39 ENST00000405140.7
clusterin
chr22_+_22327298 15.32 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr10_+_132332136 15.01 ENST00000344079.9
ENST00000625755.2
ENST00000368614.8
leucine rich repeat containing 27
chrX_+_154295788 14.97 ENST00000369915.8
transketolase like 1
chr12_+_130337872 14.93 ENST00000245255.7
piwi like RNA-mediated gene silencing 1
chr14_-_105644790 14.84 ENST00000641095.1
ENST00000390545.3
immunoglobulin heavy constant gamma 2 (G2m marker)
chr19_+_57240610 14.77 ENST00000414468.3
zinc finger protein 805
chr19_-_17075038 14.71 ENST00000593360.1
HAUS augmin like complex subunit 8
chr8_+_143734133 14.65 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr21_+_5022493 14.56 ENST00000612610.4
ENST00000620481.4
ENST00000623960.4
ENST00000623795.1
novel protein, similar to inducible T-cell co-stimulator ligand ICOSLG
chr9_+_84668485 14.51 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chr3_-_58587033 14.47 ENST00000447756.2
family with sequence similarity 107 member A
chr22_+_22906342 14.44 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr20_-_57525097 14.37 ENST00000423479.7
ENST00000502686.6
ENST00000433949.7
ENST00000539382.5
ENST00000608903.5
CCCTC-binding factor like
chr13_-_43879696 14.35 ENST00000444614.8
coiled-coil domain containing 122
chr18_-_77017042 14.08 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
myelin basic protein
chr17_-_5234801 14.04 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr9_-_95317671 13.98 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chr22_+_22380766 13.86 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr6_-_32530268 13.75 ENST00000374975.4
major histocompatibility complex, class II, DR beta 5
chr10_+_46579084 13.68 ENST00000512997.5
ENST00000374321.9
ENST00000503753.5
synaptotagmin 15
chr5_-_131796921 13.60 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr1_-_37692205 13.50 ENST00000477060.1
ENST00000491981.5
ENST00000488137.5
ENST00000619962.1
chromosome 1 open reading frame 109
chr5_-_132556809 13.49 ENST00000450655.1
interleukin 5
chr8_-_70071226 13.41 ENST00000276594.3
PR/SET domain 14
chr19_+_36605292 13.39 ENST00000460670.5
ENST00000292928.7
ENST00000439428.5
zinc finger protein 382
chr2_+_11133119 13.00 ENST00000381585.8
ENST00000405022.3
chromosome 2 open reading frame 50
chr19_+_57231014 12.99 ENST00000302804.12
aurora kinase C
chr19_-_5622768 12.89 ENST00000252542.9
scaffold attachment factor B2
chr21_+_45405117 12.80 ENST00000651438.1
collagen type XVIII alpha 1 chain
chr12_+_111766887 12.74 ENST00000416293.7
ENST00000261733.7
aldehyde dehydrogenase 2 family member
chr15_+_74130551 12.61 ENST00000453268.3
immunoglobulin superfamily containing leucine rich repeat 2
chr20_+_32052192 12.54 ENST00000375862.7
ENST00000629881.2
ENST00000375852.5
ENST00000520553.5
ENST00000518730.5
HCK proto-oncogene, Src family tyrosine kinase
chr1_+_1324790 12.46 ENST00000343938.9
ceramide-1-phosphate transfer protein
chr21_-_43659460 12.46 ENST00000443485.1
ENST00000291560.7
heat shock transcription factor 2 binding protein
chr11_+_117199363 12.34 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chrX_+_153972729 12.30 ENST00000369982.5
transmembrane protein 187
chr19_-_54222978 12.24 ENST00000245620.13
ENST00000346401.10
ENST00000445347.1
leukocyte immunoglobulin like receptor B3
chr11_+_314010 12.24 ENST00000680699.1
ENST00000681938.1
ENST00000679380.1
ENST00000680938.1
ENST00000408968.4
ENST00000681180.1
ENST00000681426.1
ENST00000680696.1
interferon induced transmembrane protein 1
chr20_-_59933623 12.24 ENST00000357552.8
ENST00000425931.1
synaptonemal complex protein 2
chr16_-_30021288 12.23 ENST00000574405.5
double C2 domain alpha
chr4_-_170026333 12.22 ENST00000504999.1
microfibril associated protein 3 like
chr6_+_33075952 12.18 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr19_+_57231001 12.16 ENST00000415300.6
aurora kinase C
chr9_+_127397184 12.13 ENST00000419917.5
ENST00000373352.5
ENST00000373360.7
solute carrier family 2 member 8
chr7_+_156949704 12.11 ENST00000275820.4
nucleolar protein with MIF4G domain 1
chr1_-_11805977 12.10 ENST00000376486.3
methylenetetrahydrofolate reductase
chr22_-_50529990 12.06 ENST00000425169.1
ENST00000487577.5
ENST00000651401.1
ENST00000252029.8
ENST00000395680.6
ENST00000395681.6
ENST00000651196.1
ENST00000650719.1
ENST00000395678.7
thymidine phosphorylase
chr22_+_22697789 12.04 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr6_-_32589833 11.91 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr19_+_50476496 11.86 ENST00000597426.1
ENST00000376918.7
ENST00000334976.11
ENST00000598585.1
ER membrane protein complex subunit 10
chr21_+_46458846 11.78 ENST00000417564.3
ENST00000651436.1
ENST00000400274.5
ENST00000457905.7
ENST00000466639.5
ENST00000435722.7
disco interacting protein 2 homolog A
chr12_+_50925007 11.73 ENST00000332160.5
methyltransferase like 7A
chr19_+_43581037 11.72 ENST00000562365.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr19_-_5978078 11.64 ENST00000592621.5
ENST00000034275.12
ENST00000591092.5
ENST00000591333.5
ENST00000590623.5
ENST00000439268.6
RAN binding protein 3
chr22_+_22922594 11.64 ENST00000390331.3
immunoglobulin lambda constant 7
chr14_-_105708627 11.60 ENST00000641837.1
ENST00000390547.3
immunoglobulin heavy constant alpha 1
chr7_+_65873242 11.57 ENST00000648179.1
vitamin K epoxide reductase complex subunit 1 like 1
chr3_-_38029604 11.55 ENST00000334661.5
phospholipase C delta 1
chr4_-_1208825 11.51 ENST00000511679.5
ENST00000617421.4
spondin 2
chr5_+_35617838 11.46 ENST00000282469.10
ENST00000509059.5
ENST00000637569.1
ENST00000356031.8
ENST00000510777.5
sperm flagellar 2
chr19_-_5978133 11.39 ENST00000340578.10
ENST00000591736.5
ENST00000587479.2
RAN binding protein 3
chr16_-_15856994 11.34 ENST00000576790.7
ENST00000396324.7
ENST00000300036.6
ENST00000452625.7
myosin heavy chain 11
chr22_-_19525369 11.31 ENST00000403084.1
ENST00000413119.2
claudin 5
chr20_+_62183021 11.29 ENST00000370823.8
ENST00000448254.1
mitochondrial ribosome associated GTPase 2
chr17_-_57850010 11.27 ENST00000313608.13
ENST00000578444.1
ENST00000579380.1
mitochondrial ribosomal protein S23
chr5_-_131797030 11.26 ENST00000615660.4
folliculin interacting protein 1
chr4_-_57110373 11.25 ENST00000295666.6
ENST00000514062.2
insulin like growth factor binding protein 7
chr19_+_47256518 11.21 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chr8_+_24914942 11.20 ENST00000433454.3
neurofilament medium
chr2_+_90100235 11.15 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr11_+_62671664 11.14 ENST00000377953.4
ubiquinol-cytochrome c reductase complex assembly factor 3
chr22_+_22899481 11.14 ENST00000390322.2
immunoglobulin lambda joining 2
chr16_+_4734457 11.07 ENST00000590191.1
chromosome 16 open reading frame 71
chr19_+_57320461 11.05 ENST00000321545.5
zinc finger protein 543
chr16_+_84145256 11.04 ENST00000378553.10
dynein axonemal assembly factor 1
chr7_+_24284181 11.04 ENST00000407573.5
ENST00000242152.7
neuropeptide Y
chr16_+_6019663 10.98 ENST00000422070.8
RNA binding fox-1 homolog 1
chr2_-_218002988 10.92 ENST00000682258.1
ENST00000446903.5
tensin 1
chr2_+_95025700 10.91 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
mal, T cell differentiation protein
chrX_-_2500555 10.89 ENST00000381218.8
zinc finger BED-type containing 1
chr5_-_112419251 10.88 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr14_-_105863862 10.88 ENST00000488476.1
immunoglobulin heavy joining 5
chr19_+_19033575 10.80 ENST00000392335.6
ENST00000537263.5
ENST00000540707.5
ENST00000535612.6
ENST00000541725.5
ENST00000269932.10
ENST00000546344.5
ENST00000540792.5
ENST00000536098.5
ENST00000541898.5
armadillo repeat containing 6
chr5_-_161548124 10.75 ENST00000520240.5
ENST00000517901.5
ENST00000353437.10
gamma-aminobutyric acid type A receptor subunit beta2
chr3_+_40524878 10.75 ENST00000403205.6
ENST00000310898.5
ENST00000431278.5
ENST00000339296.10
zinc finger protein 621
chr8_-_27605271 10.74 ENST00000522098.1
clusterin
chr9_+_136665745 10.74 ENST00000371698.3
EGF like domain multiple 7
chr4_-_1172575 10.72 ENST00000290902.10
spondin 2
chr19_-_13906062 10.64 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr10_-_47763592 10.58 ENST00000615923.4
ENST00000623662.4
novel protein identical to synaptotagmin XV
chr1_-_230745574 10.56 ENST00000681269.1
angiotensinogen
chr8_-_27600000 10.52 ENST00000521770.1
clusterin
chr17_-_35986649 10.52 ENST00000622526.1
ENST00000620991.1
ENST00000618404.5
C-C motif chemokine ligand 14
chr7_-_101200912 10.50 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr19_+_35138993 10.48 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr2_+_219627394 10.45 ENST00000373760.6
solute carrier family 4 member 3
chr16_+_590056 10.45 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C, member RAS oncogene family
chr13_+_95552701 10.40 ENST00000299339.3
claudin 10
chr11_+_82901698 10.36 ENST00000524921.5
ENST00000528759.5
ENST00000525361.5
ENST00000532764.5
ENST00000532589.5
ENST00000533655.6
ENST00000525388.5
DNA damage induced apoptosis suppressor
chr19_+_44905785 10.36 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr1_+_26317950 10.27 ENST00000374213.3
CD52 molecule
chr15_+_75347610 10.25 ENST00000564784.5
ENST00000569035.5
nei like DNA glycosylase 1
chr19_+_5681000 10.24 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
hydroxysteroid 11-beta dehydrogenase 1 like
chr17_-_7294592 10.22 ENST00000007699.10
Y-box binding protein 2
chr21_-_36966372 10.17 ENST00000399120.5
holocarboxylase synthetase
chr16_+_20806517 10.14 ENST00000348433.10
ENST00000568501.5
ENST00000261377.11
ENST00000566276.5
RNA exonuclease 5
chr16_-_1793719 10.08 ENST00000415638.3
insulin like growth factor binding protein acid labile subunit
chr3_-_128052166 10.06 ENST00000648300.1
monoglyceride lipase
chr15_+_90234189 10.04 ENST00000559204.6
ENST00000329600.8
ENST00000558291.2
GDP-D-glucose phosphorylase 1
chr19_+_489140 10.02 ENST00000587541.5
mucosal vascular addressin cell adhesion molecule 1
chr6_-_28587250 9.96 ENST00000452236.3
zinc finger BED-type containing 9
chr8_+_140511286 9.94 ENST00000519533.1
ENST00000220913.10
chromatin accessibility complex subunit 1
chrX_+_16719595 9.84 ENST00000380155.4
synapse associated protein 1
chr8_+_141391989 9.83 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
protein tyrosine phosphatase 4A3
chr12_-_124567464 9.81 ENST00000458234.5
nuclear receptor corepressor 2
chrX_+_154585120 9.80 ENST00000593606.3
ENST00000599837.3
cancer/testis antigen 1A
chr1_+_232950580 9.78 ENST00000366628.10
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr7_+_73328152 9.77 ENST00000252037.5
ENST00000431982.6
FKBP prolyl isomerase family member 6 (inactive)
chr21_-_44240840 9.76 ENST00000344330.8
ENST00000407780.7
ENST00000400379.7
ENST00000400377.3
inducible T cell costimulator ligand
chr9_+_121286586 9.76 ENST00000545652.6
gelsolin
chr16_+_3046552 9.75 ENST00000336577.9
matrix metallopeptidase 25
chr11_+_1870252 9.70 ENST00000612798.4
lymphocyte specific protein 1
chr16_+_1984182 9.67 ENST00000248114.7
ENST00000569451.1
ENST00000561710.1
growth factor, augmenter of liver regeneration
chr3_-_126475863 9.65 ENST00000336332.5
ENST00000389709.8
ZXD family zinc finger C
chr1_-_39672080 9.63 ENST00000235628.2
5'-nucleotidase, cytosolic IA
chr20_-_4823597 9.63 ENST00000379400.8
Ras association domain family member 2
chr6_+_31586859 9.62 ENST00000433492.5
leukocyte specific transcript 1
chr11_-_117876719 9.60 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr19_+_4969105 9.55 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chr20_-_23049659 9.54 ENST00000377103.3
thrombomodulin
chr9_-_113056670 9.51 ENST00000553380.1
ENST00000374227.8
ZFP37 zinc finger protein
chr4_+_139015751 9.45 ENST00000280614.4
nocturnin
chr4_+_674559 9.44 ENST00000511290.5
myosin light chain 5
chr10_-_29735787 9.43 ENST00000375400.7
supervillin
chr19_+_50203607 9.43 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr20_+_1226035 9.43 ENST00000683101.1
ENST00000402452.5
ENST00000409241.5
ENST00000246108.3
RAD21 cohesin complex component like 1
chr9_-_34710069 9.41 ENST00000378792.1
ENST00000259607.7
C-C motif chemokine ligand 21
chr20_+_18288477 9.38 ENST00000377671.7
ENST00000360010.9
ENST00000628216.2
ENST00000425686.3
ENST00000434018.5
ENST00000630056.1
zinc finger protein 133
chr16_-_66552460 9.38 ENST00000678015.1
ENST00000569718.6
ENST00000678314.1
ENST00000562484.2
thymidine kinase 2
chr5_-_140633167 9.38 ENST00000302014.11
CD14 molecule
chr1_-_52921681 9.37 ENST00000467988.2
ENST00000358358.9
ENST00000371522.9
ENST00000536120.5
enoyl-CoA hydratase domain containing 2
chr7_+_73328177 9.36 ENST00000442793.5
ENST00000413573.6
FKBP prolyl isomerase family member 6 (inactive)
chr2_+_24793098 9.34 ENST00000473706.5
centromere protein O
chr6_-_26017779 9.33 ENST00000244573.5
H1.1 linker histone, cluster member
chr19_+_49512613 9.33 ENST00000599701.5
ENST00000221466.10
Fc fragment of IgG receptor and transporter
chr15_+_28885955 9.30 ENST00000558402.5
ENST00000683413.1
ENST00000558330.5
amyloid beta precursor protein binding family A member 2
chrX_-_154295085 9.29 ENST00000617225.4
ENST00000619903.4
testis expressed 28
chr11_-_117876892 9.24 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr16_+_22814154 9.21 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr19_-_12610799 9.20 ENST00000311437.11
zinc finger protein 490
chr11_-_118790923 9.19 ENST00000620157.4
ENST00000526070.2
DEAD-box helicase 6
chr9_-_137028271 9.16 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr3_+_9809948 9.16 ENST00000426895.9
tubulin tyrosine ligase like 3
chr16_+_89217697 9.12 ENST00000433976.7
ENST00000564906.5
ENST00000620195.4
zinc finger protein 778
chr5_-_176630517 9.08 ENST00000393693.7
ENST00000614675.4
synuclein beta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.0 47.9 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
13.5 67.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
6.9 20.7 GO:0006982 response to lipid hydroperoxide(GO:0006982)
6.2 31.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
5.6 22.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
5.6 39.0 GO:0034587 piRNA metabolic process(GO:0034587)
5.5 32.9 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
4.6 18.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
4.5 18.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
4.5 13.4 GO:1905154 negative regulation of membrane invagination(GO:1905154)
4.5 26.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
4.4 21.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
4.4 30.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
4.2 17.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
4.2 21.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
4.2 25.0 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
4.1 8.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
4.1 12.2 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
3.9 15.6 GO:0035627 ceramide transport(GO:0035627)
3.9 11.7 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
3.9 27.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
3.9 15.4 GO:0002399 MHC class II protein complex assembly(GO:0002399)
3.8 11.5 GO:0071848 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
3.8 11.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
3.7 11.0 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
3.7 3.7 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
3.7 33.0 GO:0006069 ethanol oxidation(GO:0006069)
3.6 18.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
3.6 14.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
3.6 17.8 GO:0006041 glucosamine metabolic process(GO:0006041)
3.5 10.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
3.5 7.0 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
3.5 10.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
3.4 24.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
3.4 10.2 GO:0009386 translational attenuation(GO:0009386)
3.4 10.2 GO:0036146 cellular response to mycotoxin(GO:0036146)
3.4 3.4 GO:0043379 memory T cell differentiation(GO:0043379)
3.4 10.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
3.3 13.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
3.3 9.8 GO:0035720 intraciliary anterograde transport(GO:0035720)
3.3 9.8 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
3.3 16.3 GO:0061107 seminal vesicle development(GO:0061107)
3.2 16.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
3.2 13.0 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
3.2 242.7 GO:0006910 phagocytosis, recognition(GO:0006910)
3.2 12.9 GO:0071724 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
3.2 3.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
3.1 15.7 GO:0006772 thiamine metabolic process(GO:0006772)
3.1 12.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
3.1 9.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
3.1 12.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
3.1 9.2 GO:0018094 protein polyglycylation(GO:0018094)
3.0 9.1 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
3.0 12.0 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
3.0 12.0 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.0 35.8 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
3.0 3.0 GO:1990502 dense core granule maturation(GO:1990502)
2.9 14.7 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.9 8.8 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.9 8.8 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
2.9 23.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.8 8.3 GO:1902490 regulation of sperm capacitation(GO:1902490)
2.7 18.9 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
2.7 13.4 GO:0005985 sucrose metabolic process(GO:0005985)
2.7 8.0 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
2.6 15.8 GO:0014807 regulation of somitogenesis(GO:0014807)
2.6 18.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
2.6 15.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
2.5 7.6 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
2.5 7.5 GO:2001301 cellular response to interleukin-13(GO:0035963) regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
2.4 9.8 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
2.4 7.3 GO:0042412 taurine biosynthetic process(GO:0042412)
2.4 7.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.4 21.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.4 7.2 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.4 7.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
2.4 14.4 GO:0016926 protein desumoylation(GO:0016926)
2.4 21.4 GO:0002679 respiratory burst involved in defense response(GO:0002679)
2.4 4.8 GO:0001575 globoside metabolic process(GO:0001575)
2.4 7.1 GO:0044565 dendritic cell proliferation(GO:0044565)
2.3 25.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
2.3 9.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
2.3 2.3 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
2.3 16.3 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
2.3 6.9 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
2.3 2.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
2.3 11.4 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
2.3 6.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
2.2 11.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
2.2 15.7 GO:0045007 depurination(GO:0045007)
2.2 8.9 GO:0046730 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
2.2 42.0 GO:0015671 oxygen transport(GO:0015671)
2.2 6.6 GO:0060988 lipid tube assembly(GO:0060988)
2.2 6.6 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
2.2 21.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.2 8.7 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
2.2 8.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
2.2 6.5 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
2.2 6.5 GO:0009447 putrescine catabolic process(GO:0009447)
2.1 4.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
2.1 12.7 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
2.1 4.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
2.1 8.4 GO:0015942 formate metabolic process(GO:0015942)
2.1 16.8 GO:0007506 gonadal mesoderm development(GO:0007506)
2.1 8.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
2.1 6.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
2.1 16.4 GO:0001955 blood vessel maturation(GO:0001955)
2.0 2.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
2.0 6.1 GO:0002125 maternal aggressive behavior(GO:0002125)
2.0 4.1 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
2.0 6.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
2.0 6.0 GO:0061760 antifungal innate immune response(GO:0061760)
2.0 6.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
2.0 14.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.0 6.0 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
2.0 6.0 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
2.0 11.9 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
2.0 9.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.0 6.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
2.0 5.9 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
2.0 27.5 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
1.9 1.9 GO:2000416 regulation of eosinophil migration(GO:2000416) negative regulation of eosinophil migration(GO:2000417)
1.9 19.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
1.9 9.7 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
1.9 1.9 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
1.9 3.9 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
1.9 9.7 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
1.9 5.8 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
1.9 13.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.9 7.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.9 7.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.9 11.4 GO:0035617 stress granule disassembly(GO:0035617)
1.9 5.7 GO:0060005 vestibular reflex(GO:0060005)
1.9 7.5 GO:0003095 pressure natriuresis(GO:0003095)
1.9 1.9 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
1.8 7.4 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
1.8 5.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.8 9.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.8 12.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.8 3.7 GO:1902623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
1.8 16.3 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.8 5.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.8 14.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.8 5.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.7 8.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.7 8.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.7 34.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.7 3.5 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.7 3.4 GO:0044793 negative regulation by host of viral process(GO:0044793)
1.7 5.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.7 3.4 GO:0046208 spermine catabolic process(GO:0046208)
1.7 28.8 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
1.7 5.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.7 5.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.7 5.0 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
1.7 1.7 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
1.7 1.7 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.7 5.0 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.7 36.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
1.7 13.2 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.6 8.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.6 3.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.6 11.4 GO:0048241 epinephrine transport(GO:0048241)
1.6 3.3 GO:0071221 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
1.6 4.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.6 4.9 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.6 17.6 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
1.6 6.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.6 12.7 GO:0042373 vitamin K metabolic process(GO:0042373)
1.6 22.2 GO:0006751 glutathione catabolic process(GO:0006751)
1.6 9.5 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
1.6 20.4 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
1.6 9.4 GO:0046092 deoxycytidine metabolic process(GO:0046092)
1.6 4.7 GO:0042360 vitamin E metabolic process(GO:0042360)
1.6 1.6 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
1.5 128.7 GO:0006958 complement activation, classical pathway(GO:0006958)
1.5 7.6 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
1.5 3.0 GO:1903413 cellular response to bile acid(GO:1903413)
1.5 3.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
1.5 4.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.5 4.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.5 1.5 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
1.5 1.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.5 5.9 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
1.5 16.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
1.5 7.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
1.5 4.4 GO:0009720 detection of hormone stimulus(GO:0009720)
1.5 4.4 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
1.5 8.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.5 7.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
1.4 8.7 GO:1903232 melanosome assembly(GO:1903232)
1.4 4.3 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
1.4 14.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.4 2.9 GO:0086053 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.4 5.7 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
1.4 1.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
1.4 5.7 GO:0002118 aggressive behavior(GO:0002118)
1.4 4.2 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
1.4 17.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.4 4.2 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.4 11.3 GO:0051414 response to cortisol(GO:0051414)
1.4 12.7 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.4 16.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.4 5.6 GO:0002357 defense response to tumor cell(GO:0002357)
1.4 1.4 GO:0042938 dipeptide transport(GO:0042938)
1.4 15.3 GO:0048251 elastic fiber assembly(GO:0048251)
1.4 4.2 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
1.4 4.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
1.4 8.3 GO:0061744 motor behavior(GO:0061744)
1.4 16.7 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
1.4 8.3 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
1.4 1.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
1.4 30.2 GO:0097503 sialylation(GO:0097503)
1.4 5.5 GO:0032571 response to vitamin K(GO:0032571)
1.4 9.6 GO:0015705 iodide transport(GO:0015705)
1.4 2.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
1.4 12.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.4 1.4 GO:0035962 response to interleukin-13(GO:0035962)
1.3 4.0 GO:2000374 negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
1.3 5.4 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.3 25.5 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
1.3 12.1 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
1.3 10.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
1.3 9.2 GO:0002328 pro-B cell differentiation(GO:0002328)
1.3 5.3 GO:0060023 soft palate development(GO:0060023)
1.3 5.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.3 3.9 GO:2001226 negative regulation of chloride transport(GO:2001226)
1.3 9.0 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.3 6.4 GO:0032902 nerve growth factor production(GO:0032902)
1.3 32.0 GO:0007141 male meiosis I(GO:0007141)
1.3 12.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.3 54.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.3 3.8 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
1.3 2.5 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
1.3 5.0 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
1.3 5.0 GO:0015670 carbon dioxide transport(GO:0015670)
1.3 5.0 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.2 6.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.2 5.0 GO:0030259 lipid glycosylation(GO:0030259)
1.2 34.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.2 11.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.2 3.7 GO:1900060 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
1.2 6.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.2 2.5 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
1.2 4.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.2 1.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
1.2 12.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.2 1.2 GO:0035634 response to stilbenoid(GO:0035634)
1.2 1.2 GO:0070253 somatostatin secretion(GO:0070253)
1.2 12.0 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.2 4.8 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
1.2 3.6 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.2 1.2 GO:1903939 regulation of TORC2 signaling(GO:1903939)
1.2 2.4 GO:0060214 endocardium formation(GO:0060214)
1.2 3.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.2 4.7 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.2 5.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.2 4.7 GO:0036369 transcription factor catabolic process(GO:0036369)
1.2 5.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240) mesenchyme migration(GO:0090131)
1.2 3.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.2 3.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
1.1 3.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.1 3.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
1.1 3.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.1 4.6 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.1 1.1 GO:0090230 regulation of centromere complex assembly(GO:0090230)
1.1 9.1 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452)
1.1 3.4 GO:0071317 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
1.1 13.5 GO:0015074 DNA integration(GO:0015074)
1.1 3.4 GO:0050957 equilibrioception(GO:0050957)
1.1 13.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.1 4.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.1 10.0 GO:0015693 magnesium ion transport(GO:0015693)
1.1 4.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.1 4.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.1 5.5 GO:0030242 pexophagy(GO:0030242)
1.1 4.4 GO:0042321 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321)
1.1 4.3 GO:0080154 regulation of fertilization(GO:0080154)
1.1 4.3 GO:1905225 cellular response to glycoprotein(GO:1904588) response to thyrotropin-releasing hormone(GO:1905225) cellular response to thyrotropin-releasing hormone(GO:1905229)
1.1 8.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.1 1.1 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
1.1 6.5 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.1 5.3 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.1 3.2 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
1.1 18.0 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
1.1 3.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.1 5.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.0 6.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.0 5.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
1.0 8.3 GO:0001887 selenium compound metabolic process(GO:0001887)
1.0 3.1 GO:0030035 microspike assembly(GO:0030035)
1.0 12.4 GO:0070254 mucus secretion(GO:0070254)
1.0 6.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.0 7.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.0 2.1 GO:1902617 response to fluoride(GO:1902617)
1.0 6.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.0 4.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.0 5.1 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.0 5.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.0 3.0 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
1.0 7.0 GO:0023041 neuronal signal transduction(GO:0023041)
1.0 9.0 GO:0009950 dorsal/ventral axis specification(GO:0009950)
1.0 1.0 GO:0019532 oxalate transport(GO:0019532)
1.0 13.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.0 6.0 GO:0033504 floor plate development(GO:0033504)
1.0 5.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.0 7.9 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
1.0 8.9 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
1.0 12.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.0 4.9 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.0 4.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.0 1.0 GO:0042095 interferon-gamma biosynthetic process(GO:0042095) regulation of interferon-gamma biosynthetic process(GO:0045072)
1.0 3.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
1.0 1.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.0 15.4 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
1.0 10.6 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
1.0 15.3 GO:0042420 dopamine catabolic process(GO:0042420)
1.0 2.9 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.0 5.7 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
1.0 5.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.0 1.9 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
1.0 9.5 GO:0070544 histone H3-K36 demethylation(GO:0070544)
1.0 8.6 GO:0048680 positive regulation of axon regeneration(GO:0048680)
1.0 28.5 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.9 1.9 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.9 1.9 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.9 5.7 GO:1903960 negative regulation of anion transmembrane transport(GO:1903960)
0.9 4.7 GO:0046618 drug export(GO:0046618)
0.9 1.9 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.9 1.9 GO:0018879 biphenyl metabolic process(GO:0018879)
0.9 9.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.9 12.2 GO:2001204 regulation of osteoclast development(GO:2001204)
0.9 1.9 GO:0035624 receptor transactivation(GO:0035624)
0.9 11.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.9 2.8 GO:0090291 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291)
0.9 6.5 GO:1901563 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
0.9 2.8 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.9 6.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.9 3.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.9 1.9 GO:0021586 pons maturation(GO:0021586)
0.9 5.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.9 3.7 GO:0002215 defense response to nematode(GO:0002215)
0.9 15.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.9 5.5 GO:0007497 posterior midgut development(GO:0007497)
0.9 6.4 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.9 1.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.9 9.1 GO:0015824 proline transport(GO:0015824)
0.9 5.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.9 1.8 GO:0002326 B cell lineage commitment(GO:0002326)
0.9 64.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.9 9.0 GO:0014850 response to muscle activity(GO:0014850)
0.9 5.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.9 13.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.9 4.5 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.9 13.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.9 5.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.9 2.7 GO:1905073 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.9 1.8 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.9 2.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.9 8.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.9 8.8 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.9 4.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 2.6 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.9 6.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.9 3.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.9 11.3 GO:0044065 regulation of respiratory system process(GO:0044065)
0.9 5.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.9 6.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.9 12.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.9 5.2 GO:0018343 protein farnesylation(GO:0018343)
0.9 3.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 2.6 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.9 6.9 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.9 2.6 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.9 2.6 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.8 4.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.8 1.7 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.8 3.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.8 3.3 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.8 2.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.8 3.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.8 5.0 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.8 3.3 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.8 8.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.8 4.9 GO:0022605 ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.8 51.3 GO:0006968 cellular defense response(GO:0006968)
0.8 13.0 GO:0097186 amelogenesis(GO:0097186)
0.8 4.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.8 10.5 GO:0036124 histone H3-K9 trimethylation(GO:0036124)
0.8 8.9 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.8 7.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.8 1.6 GO:0070673 response to interleukin-18(GO:0070673)
0.8 4.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.8 4.8 GO:0038016 insulin receptor internalization(GO:0038016)
0.8 1.6 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.8 2.4 GO:0042048 olfactory behavior(GO:0042048)
0.8 8.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.8 3.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.8 1.6 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.8 12.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.8 1.6 GO:0021873 forebrain neuroblast division(GO:0021873)
0.8 4.7 GO:0008218 bioluminescence(GO:0008218)
0.8 14.8 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.8 0.8 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.8 3.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.8 7.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.8 2.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.8 3.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.8 3.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.8 3.1 GO:0008343 adult feeding behavior(GO:0008343)
0.8 3.8 GO:1904526 regulation of microtubule binding(GO:1904526)
0.8 6.1 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.8 4.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.8 2.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.8 1.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.8 3.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.8 4.5 GO:0071105 response to interleukin-11(GO:0071105)
0.8 0.8 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.8 6.0 GO:0006013 mannose metabolic process(GO:0006013)
0.8 6.0 GO:0015747 urate transport(GO:0015747)
0.7 6.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.7 11.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.7 10.5 GO:0006702 androgen biosynthetic process(GO:0006702)
0.7 2.2 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.7 8.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.7 20.1 GO:0071420 cellular response to histamine(GO:0071420)
0.7 6.7 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.7 2.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.7 11.1 GO:0015874 norepinephrine transport(GO:0015874)
0.7 4.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.7 2.9 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.7 26.4 GO:0048599 oocyte development(GO:0048599)
0.7 38.9 GO:0015701 bicarbonate transport(GO:0015701)
0.7 5.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7 2.9 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.7 5.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.7 2.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.7 0.7 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.7 4.4 GO:0010265 SCF complex assembly(GO:0010265)
0.7 10.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.7 2.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.7 10.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.7 8.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.7 17.2 GO:0097502 mannosylation(GO:0097502)
0.7 3.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.7 5.7 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.7 2.8 GO:0010193 response to ozone(GO:0010193)
0.7 4.3 GO:0034349 glial cell apoptotic process(GO:0034349)
0.7 8.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.7 2.8 GO:0071918 urea transmembrane transport(GO:0071918)
0.7 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.7 2.1 GO:1903006 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.7 2.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.7 2.8 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.7 15.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.7 1.4 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.7 6.1 GO:0060973 cell migration involved in heart development(GO:0060973)
0.7 2.0 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.7 1.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.7 2.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.7 2.7 GO:0019086 late viral transcription(GO:0019086)
0.7 3.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.7 1.3 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.7 2.0 GO:1900426 positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of defense response to bacterium(GO:1900426)
0.7 1.3 GO:1904640 response to methionine(GO:1904640)
0.7 5.4 GO:0007135 meiosis II(GO:0007135)
0.7 3.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.7 7.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.7 2.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.7 3.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.7 17.9 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.7 1.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.7 3.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 4.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.7 1.3 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.7 5.9 GO:0048102 autophagic cell death(GO:0048102)
0.7 2.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.7 2.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.6 5.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.6 6.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.6 13.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.6 5.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.6 3.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.6 2.6 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 1.9 GO:0048370 vacuolar phosphate transport(GO:0007037) lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.6 6.4 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.6 8.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.6 2.6 GO:1901317 regulation of sperm motility(GO:1901317)
0.6 1.3 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.6 3.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.6 3.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.6 8.3 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.6 7.0 GO:0014029 neural crest formation(GO:0014029)
0.6 3.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.6 7.0 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.6 1.3 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.6 5.7 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.6 2.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.6 4.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.6 5.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.6 10.7 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.6 8.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.6 1.9 GO:0042631 cellular response to water deprivation(GO:0042631)
0.6 2.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.6 1.9 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.6 9.8 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.6 6.1 GO:0046958 nonassociative learning(GO:0046958)
0.6 3.7 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.6 4.9 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.6 1.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.6 9.8 GO:0060022 hard palate development(GO:0060022)
0.6 12.8 GO:0007398 ectoderm development(GO:0007398)
0.6 1.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.6 3.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.6 1.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.6 15.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6 13.9 GO:0015695 organic cation transport(GO:0015695)
0.6 3.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.6 15.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.6 8.4 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.6 4.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.6 3.0 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.6 38.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.6 4.2 GO:0061709 reticulophagy(GO:0061709)
0.6 3.0 GO:1903358 regulation of Golgi organization(GO:1903358)
0.6 2.4 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.6 4.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.6 17.1 GO:0048753 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.6 12.4 GO:0048820 hair follicle maturation(GO:0048820)
0.6 1.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.6 1.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.6 2.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.6 1.7 GO:0090521 regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521)
0.6 4.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.6 6.9 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.6 4.0 GO:0080009 mRNA methylation(GO:0080009)
0.6 2.9 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.6 2.9 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6 2.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.6 1.7 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.6 3.4 GO:0021633 optic nerve structural organization(GO:0021633)
0.6 1.1 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.6 1.1 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.6 1.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.6 3.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.6 1.7 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.6 3.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.6 2.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.6 1.1 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.5 4.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.5 3.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.5 4.9 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.5 4.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.5 9.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.5 6.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.5 3.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.5 8.5 GO:0051194 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.5 2.6 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 8.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 12.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.5 2.6 GO:0060068 vagina development(GO:0060068)
0.5 3.1 GO:0035063 nuclear speck organization(GO:0035063)
0.5 12.3 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.5 4.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.5 6.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.5 1.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.5 2.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.5 33.3 GO:0019226 transmission of nerve impulse(GO:0019226)
0.5 4.0 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.5 7.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.5 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.5 4.5 GO:0070307 lens fiber cell development(GO:0070307)
0.5 8.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.5 1.0 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.5 1.0 GO:1990834 response to odorant(GO:1990834)
0.5 0.5 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.5 2.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.5 2.0 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.5 1.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5 1.9 GO:1903974 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.5 2.4 GO:0021936 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699) regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.5 3.4 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.5 7.2 GO:0007140 male meiosis(GO:0007140)
0.5 1.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5 7.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.5 1.4 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.5 4.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.5 2.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 1.4 GO:0001927 exocyst assembly(GO:0001927)
0.5 0.9 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.5 6.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.5 20.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.5 2.8 GO:0034201 response to oleic acid(GO:0034201)
0.5 8.5 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.5 1.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 8.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.5 1.4 GO:0015793 glycerol transport(GO:0015793)
0.5 5.6 GO:0001946 lymphangiogenesis(GO:0001946)
0.5 5.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.5 2.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 3.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.5 1.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.5 1.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.5 0.9 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.4 2.2 GO:0051546 keratinocyte migration(GO:0051546)
0.4 1.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.4 3.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.4 11.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 5.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.4 6.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 4.4 GO:0021756 striatum development(GO:0021756)
0.4 15.8 GO:0016266 O-glycan processing(GO:0016266)
0.4 2.6 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.4 5.2 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.4 3.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 2.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 4.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.4 5.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.4 1.3 GO:0000050 urea cycle(GO:0000050)
0.4 4.6 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.4 5.0 GO:0009299 mRNA transcription(GO:0009299)
0.4 0.8 GO:0071104 response to interleukin-9(GO:0071104)
0.4 5.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.4 7.4 GO:0045124 regulation of bone resorption(GO:0045124)
0.4 1.2 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.4 4.9 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.4 5.7 GO:0006706 steroid catabolic process(GO:0006706)
0.4 2.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.4 3.7 GO:0060073 micturition(GO:0060073)
0.4 7.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.4 1.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.4 2.0 GO:0016139 glycoside catabolic process(GO:0016139)
0.4 3.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.2 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.4 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.4 1.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 5.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.4 1.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 2.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 4.0 GO:2001300 lipoxin metabolic process(GO:2001300)
0.4 6.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.4 3.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.4 2.0 GO:0048710 regulation of astrocyte differentiation(GO:0048710)
0.4 1.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4 1.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.4 3.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.4 8.9 GO:0030488 tRNA methylation(GO:0030488)
0.4 3.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.4 1.2 GO:0099558 motor learning(GO:0061743) maintenance of synapse structure(GO:0099558)
0.4 1.2 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4 5.0 GO:0035082 axoneme assembly(GO:0035082)
0.4 12.0 GO:0010518 positive regulation of phospholipase activity(GO:0010518)
0.4 5.0 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.4 1.9 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.4 3.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.4 3.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 3.0 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.4 3.4 GO:0022038 corpus callosum development(GO:0022038)
0.4 2.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.4 2.3 GO:0007320 insemination(GO:0007320)
0.4 1.9 GO:0072602 interleukin-4 secretion(GO:0072602)
0.4 3.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.4 2.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 1.5 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.4 5.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.4 2.6 GO:0034505 tooth mineralization(GO:0034505)
0.4 0.4 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.4 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 3.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 1.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.4 3.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 1.8 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4 5.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 5.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.4 9.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 4.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.4 1.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 1.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.4 4.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 3.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.3 3.5 GO:0002021 response to dietary excess(GO:0002021)
0.3 16.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.3 1.7 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.3 3.0 GO:0006600 creatine metabolic process(GO:0006600)
0.3 8.1 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 2.4 GO:0051026 chiasma assembly(GO:0051026)
0.3 2.7 GO:0018377 protein myristoylation(GO:0018377)
0.3 1.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 2.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.3 1.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 6.6 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.3 1.6 GO:0086064 cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.3 18.9 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.3 12.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.3 4.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3 6.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.3 12.5 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.3 1.3 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.3 1.0 GO:0016137 glycoside metabolic process(GO:0016137)
0.3 1.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.3 5.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 6.9 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.3 2.8 GO:0031269 pseudopodium assembly(GO:0031269)
0.3 0.9 GO:2000342 negative regulation of interleukin-8 biosynthetic process(GO:0045415) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 2.5 GO:0090102 cochlea development(GO:0090102)
0.3 4.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 8.4 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.3 3.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 3.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.3 2.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.3 3.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.3 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.3 4.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.3 3.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.3 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 4.0 GO:0032060 bleb assembly(GO:0032060)
0.3 1.7 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.3 2.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.3 1.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 5.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.3 2.5 GO:0003407 neural retina development(GO:0003407)
0.3 6.7 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.3 1.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.3 4.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 1.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.3 1.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 1.9 GO:0006568 tryptophan metabolic process(GO:0006568)
0.3 1.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3 2.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 18.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 0.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.3 2.4 GO:0048240 sperm capacitation(GO:0048240)
0.3 3.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 3.9 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 2.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 2.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.3 3.9 GO:0007340 acrosome reaction(GO:0007340)
0.3 25.4 GO:0002377 immunoglobulin production(GO:0002377)
0.3 17.1 GO:0030574 collagen catabolic process(GO:0030574)
0.3 1.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 1.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 1.0 GO:0060017 parathyroid gland development(GO:0060017)
0.3 0.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 2.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2 14.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 4.9 GO:0030317 sperm motility(GO:0030317)
0.2 1.0 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.2 2.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.2 2.0 GO:1902116 negative regulation of centriole replication(GO:0046600) negative regulation of organelle assembly(GO:1902116)
0.2 2.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 0.7 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.2 1.7 GO:0042908 xenobiotic transport(GO:0042908)
0.2 0.5 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.2 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 2.4 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 1.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 0.7 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.2 0.7 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.2 2.7 GO:0045730 respiratory burst(GO:0045730)
0.2 0.7 GO:0032966 negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.2 3.4 GO:0031167 rRNA methylation(GO:0031167)
0.2 5.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 2.4 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.2 8.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 15.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.2 30.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 1.9 GO:0060411 cardiac septum morphogenesis(GO:0060411)
0.2 2.8 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.3 GO:0003177 pulmonary valve development(GO:0003177) pulmonary valve morphogenesis(GO:0003184) female genitalia development(GO:0030540) nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.2 1.1 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.2 0.6 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 0.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.2 3.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.2 1.2 GO:0010842 retina layer formation(GO:0010842)
0.2 1.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 1.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.2 1.8 GO:0009642 response to light intensity(GO:0009642)
0.2 2.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.2 0.6 GO:0060033 anatomical structure regression(GO:0060033)
0.2 1.1 GO:0035331 regulation of hippo signaling(GO:0035330) negative regulation of hippo signaling(GO:0035331)
0.2 1.1 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.2 2.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 2.4 GO:0007616 long-term memory(GO:0007616)
0.2 0.7 GO:0042756 drinking behavior(GO:0042756)
0.2 0.5 GO:0060748 mammary gland branching involved in pregnancy(GO:0060745) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 5.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 4.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 1.6 GO:0048485 sympathetic nervous system development(GO:0048485)
0.2 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 0.3 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 2.7 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.2 1.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 3.1 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.2 1.0 GO:0050433 regulation of catecholamine secretion(GO:0050433)
0.2 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 0.5 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 1.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 2.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 0.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 4.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 1.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.3 GO:0019530 taurine metabolic process(GO:0019530)
0.2 6.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 1.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.2 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 5.4 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.8 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0033629 abortive mitotic cell cycle(GO:0033277) negative regulation of cell adhesion mediated by integrin(GO:0033629) atrioventricular canal development(GO:0036302) negative regulation of growth hormone secretion(GO:0060125) intestinal epithelial cell migration(GO:0061582)
0.1 1.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 1.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 1.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 3.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.1 GO:0033684 regulation of luteinizing hormone secretion(GO:0033684)
0.1 1.0 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.1 1.7 GO:0009798 axis specification(GO:0009798)
0.1 0.9 GO:0071711 basement membrane organization(GO:0071711)
0.1 6.1 GO:0031295 T cell costimulation(GO:0031295)
0.1 1.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.5 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 3.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.6 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.1 1.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.3 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1 4.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.5 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.8 GO:0015871 choline transport(GO:0015871)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.5 GO:0071839 apoptotic process in bone marrow(GO:0071839)
0.1 0.8 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.2 GO:0071872 response to epinephrine(GO:0071871) cellular response to epinephrine stimulus(GO:0071872)
0.1 1.0 GO:0060415 muscle tissue morphogenesis(GO:0060415)
0.1 0.9 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 8.7 GO:0030072 peptide hormone secretion(GO:0030072)
0.1 0.1 GO:0071280 cellular response to copper ion(GO:0071280)
0.1 0.5 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 7.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.0 GO:2000345 regulation of hepatocyte proliferation(GO:2000345)
0.1 0.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.2 GO:0032095 regulation of response to food(GO:0032095)
0.1 1.2 GO:0097484 dendrite extension(GO:0097484)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 4.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 6.0 GO:0007586 digestion(GO:0007586)
0.1 0.5 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.0 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.1 GO:0035788 cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.5 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.2 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 1.6 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.3 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.1 0.5 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.0 GO:0048477 oogenesis(GO:0048477)
0.1 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.5 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 1.6 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.4 GO:0046710 GDP metabolic process(GO:0046710)
0.1 1.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.3 GO:0021697 cerebellar cortex formation(GO:0021697)
0.1 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:0003091 renal water homeostasis(GO:0003091)
0.1 1.8 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.1 2.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 3.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 1.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.6 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 1.0 GO:0098761 interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 2.7 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 1.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 28.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
6.1 18.3 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
5.7 22.9 GO:0005602 complement component C1 complex(GO:0005602)
5.5 105.1 GO:0042613 MHC class II protein complex(GO:0042613)
5.5 81.8 GO:0097418 neurofibrillary tangle(GO:0097418)
4.7 14.0 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
4.5 13.6 GO:0097224 sperm connecting piece(GO:0097224)
4.2 208.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
4.0 7.9 GO:0061689 tricellular tight junction(GO:0061689)
3.5 31.8 GO:0033391 chromatoid body(GO:0033391)
3.4 20.5 GO:0033269 internode region of axon(GO:0033269)
3.4 23.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
3.3 9.9 GO:0008623 CHRAC(GO:0008623)
3.2 3.2 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
3.1 9.4 GO:0030061 mitochondrial crista(GO:0030061)
3.1 9.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
3.1 3.1 GO:0031088 platelet dense granule membrane(GO:0031088)
3.1 9.3 GO:0070701 mucus layer(GO:0070701)
2.8 16.7 GO:0031501 mannosyltransferase complex(GO:0031501)
2.7 13.5 GO:0072534 perineuronal net(GO:0072534)
2.6 5.2 GO:0019814 immunoglobulin complex(GO:0019814)
2.6 15.6 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
2.5 7.5 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
2.5 7.4 GO:0045298 tubulin complex(GO:0045298)
2.4 7.3 GO:0030312 external encapsulating structure(GO:0030312)
2.4 9.6 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
2.3 22.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
2.3 25.0 GO:0043203 axon hillock(GO:0043203)
2.2 6.6 GO:0060987 lipid tube(GO:0060987)
2.2 19.7 GO:0071953 elastic fiber(GO:0071953)
2.1 8.6 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
2.1 8.2 GO:0035363 histone locus body(GO:0035363)
2.0 16.1 GO:0042583 chromaffin granule(GO:0042583)
1.9 3.9 GO:0045179 apical cortex(GO:0045179)
1.9 34.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.9 7.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.9 5.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.9 17.0 GO:0001520 outer dense fiber(GO:0001520)
1.8 5.5 GO:0031085 BLOC-3 complex(GO:0031085)
1.8 9.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
1.8 12.6 GO:0032010 phagolysosome(GO:0032010)
1.8 14.2 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.8 12.3 GO:0030991 intraciliary transport particle A(GO:0030991)
1.7 5.2 GO:0098536 deuterosome(GO:0098536)
1.7 7.0 GO:0042629 mast cell granule(GO:0042629)
1.7 10.2 GO:1990769 proximal neuron projection(GO:1990769)
1.7 10.0 GO:1990584 cardiac Troponin complex(GO:1990584)
1.7 30.0 GO:0033270 paranode region of axon(GO:0033270)
1.6 21.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.6 16.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.6 29.4 GO:0042627 chylomicron(GO:0042627)
1.6 6.5 GO:0030893 meiotic cohesin complex(GO:0030893)
1.6 9.5 GO:0005594 collagen type IX trimer(GO:0005594)
1.6 6.3 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
1.6 4.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
1.5 7.6 GO:0032444 activin responsive factor complex(GO:0032444)
1.5 14.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.4 8.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.4 4.3 GO:0043293 apoptosome(GO:0043293)
1.4 8.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
1.4 4.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.4 5.5 GO:0002139 stereocilia coupling link(GO:0002139)
1.4 5.5 GO:0033263 CORVET complex(GO:0033263)
1.4 30.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.4 16.4 GO:0005858 axonemal dynein complex(GO:0005858)
1.4 6.8 GO:0036128 CatSper complex(GO:0036128)
1.3 10.8 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.3 5.3 GO:0070695 FHF complex(GO:0070695)
1.3 5.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.3 13.2 GO:0046581 intercellular canaliculus(GO:0046581)
1.3 4.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.3 2.6 GO:0005593 FACIT collagen trimer(GO:0005593)
1.3 11.8 GO:0070652 HAUS complex(GO:0070652)
1.3 13.0 GO:0032009 early phagosome(GO:0032009)
1.3 20.1 GO:0035102 PRC1 complex(GO:0035102)
1.2 5.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.2 2.5 GO:0000805 X chromosome(GO:0000805)
1.2 11.1 GO:0036449 microtubule minus-end(GO:0036449)
1.2 3.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
1.2 6.1 GO:0032437 cuticular plate(GO:0032437)
1.2 11.9 GO:0005614 interstitial matrix(GO:0005614)
1.2 5.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.2 21.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.2 47.7 GO:0005859 muscle myosin complex(GO:0005859)
1.1 8.0 GO:0043196 varicosity(GO:0043196)
1.1 13.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.1 10.0 GO:0097427 microtubule bundle(GO:0097427)
1.1 16.7 GO:0016461 unconventional myosin complex(GO:0016461)
1.1 3.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.1 16.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.1 3.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
1.1 9.6 GO:0000137 Golgi cis cisterna(GO:0000137)
1.0 8.4 GO:0032593 insulin-responsive compartment(GO:0032593)
1.0 7.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.0 4.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
1.0 14.0 GO:0000800 lateral element(GO:0000800)
1.0 5.0 GO:0032449 CBM complex(GO:0032449)
1.0 5.0 GO:0036398 TCR signalosome(GO:0036398)
1.0 7.8 GO:0070187 telosome(GO:0070187)
0.9 29.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.9 4.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.9 31.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.9 3.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.9 10.9 GO:0016013 syntrophin complex(GO:0016013)
0.9 4.6 GO:1902560 GMP reductase complex(GO:1902560)
0.9 1.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.9 13.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.9 4.4 GO:0033010 paranodal junction(GO:0033010)
0.9 6.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 60.1 GO:0005581 collagen trimer(GO:0005581)
0.9 6.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.9 4.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.9 4.3 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.9 4.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.8 2.5 GO:0000801 central element(GO:0000801)
0.8 4.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.8 2.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.8 9.2 GO:0042611 MHC protein complex(GO:0042611)
0.8 15.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8 6.7 GO:0072487 MSL complex(GO:0072487)
0.8 4.8 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8 14.4 GO:0097225 sperm midpiece(GO:0097225)
0.8 7.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.8 8.7 GO:0097512 cardiac myofibril(GO:0097512)
0.8 2.4 GO:0097229 sperm end piece(GO:0097229)
0.8 3.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.8 3.0 GO:0016600 flotillin complex(GO:0016600)
0.7 6.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.7 5.9 GO:0034464 BBSome(GO:0034464)
0.7 11.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.7 11.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.7 3.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.7 5.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7 7.1 GO:0031045 dense core granule(GO:0031045)
0.7 10.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.7 2.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.7 2.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.7 11.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.7 24.6 GO:1902710 GABA receptor complex(GO:1902710)
0.7 5.9 GO:0044853 plasma membrane raft(GO:0044853)
0.7 3.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 3.8 GO:0070545 PeBoW complex(GO:0070545)
0.6 12.8 GO:0016342 catenin complex(GO:0016342)
0.6 4.4 GO:1990130 Iml1 complex(GO:1990130)
0.6 11.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.6 1.9 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.6 1.8 GO:1903349 omegasome membrane(GO:1903349)
0.6 4.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.6 1.8 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.6 2.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.6 39.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.6 14.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.6 3.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.6 1.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.6 13.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 10.7 GO:0036038 MKS complex(GO:0036038)
0.6 6.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.6 6.1 GO:0070449 elongin complex(GO:0070449)
0.6 2.8 GO:0071439 clathrin complex(GO:0071439)
0.6 1.7 GO:0031933 telomeric heterochromatin(GO:0031933)
0.5 7.1 GO:0005833 hemoglobin complex(GO:0005833)
0.5 11.5 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.5 7.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.5 34.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.5 1.6 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.5 2.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.5 3.1 GO:0005883 neurofilament(GO:0005883)
0.5 1.5 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.5 61.5 GO:0031225 anchored component of membrane(GO:0031225)
0.5 4.5 GO:1990909 Wnt signalosome(GO:1990909)
0.5 4.4 GO:0031904 endosome lumen(GO:0031904)
0.5 5.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 6.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.5 7.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.5 3.4 GO:1990037 Lewy body core(GO:1990037)
0.5 4.4 GO:0035253 ciliary rootlet(GO:0035253)
0.5 5.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 5.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 5.2 GO:0043218 compact myelin(GO:0043218)
0.5 2.8 GO:0097165 nuclear stress granule(GO:0097165)
0.5 5.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 3.2 GO:0030897 HOPS complex(GO:0030897)
0.4 34.8 GO:0005901 caveola(GO:0005901)
0.4 4.9 GO:0031906 late endosome lumen(GO:0031906)
0.4 2.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 2.2 GO:0032280 symmetric synapse(GO:0032280)
0.4 6.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 1.3 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.4 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.4 61.2 GO:0072562 blood microparticle(GO:0072562)
0.4 13.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 14.8 GO:0009925 basal plasma membrane(GO:0009925)
0.4 5.0 GO:0042788 polysomal ribosome(GO:0042788)
0.4 5.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.4 7.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 16.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.4 25.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.4 3.5 GO:0044294 dendritic growth cone(GO:0044294)
0.4 6.9 GO:0005922 connexon complex(GO:0005922)
0.4 6.9 GO:0048786 presynaptic active zone(GO:0048786)
0.4 3.4 GO:0045180 basal cortex(GO:0045180)
0.4 7.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.4 1.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 4.7 GO:0000242 pericentriolar material(GO:0000242)
0.4 5.4 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.3 1.7 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.3 29.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 33.5 GO:0005796 Golgi lumen(GO:0005796)
0.3 4.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 36.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.3 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.3 1.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 8.7 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.3 1.9 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 5.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 3.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 4.7 GO:0031082 BLOC complex(GO:0031082)
0.3 4.1 GO:0000145 exocyst(GO:0000145)
0.3 2.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 6.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 6.6 GO:0005902 microvillus(GO:0005902)
0.3 3.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 26.9 GO:0035579 specific granule membrane(GO:0035579)
0.3 1.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 5.5 GO:0001772 immunological synapse(GO:0001772)
0.3 1.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 1.3 GO:0070847 core mediator complex(GO:0070847)
0.2 3.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.2 62.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 1.1 GO:0032044 DSIF complex(GO:0032044)
0.2 4.5 GO:0005801 cis-Golgi network(GO:0005801)
0.2 18.8 GO:0042734 presynaptic membrane(GO:0042734)
0.2 29.3 GO:0032587 ruffle membrane(GO:0032587)
0.2 5.2 GO:0034451 centriolar satellite(GO:0034451)
0.2 29.2 GO:0055037 recycling endosome(GO:0055037)
0.2 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.8 GO:0097546 ciliary base(GO:0097546)
0.2 7.3 GO:0034707 chloride channel complex(GO:0034707)
0.2 6.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 1.0 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 7.8 GO:0001533 cornified envelope(GO:0001533)
0.2 22.5 GO:0008021 synaptic vesicle(GO:0008021)
0.2 7.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 2.8 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.1 2.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 2.4 GO:0014704 intercalated disc(GO:0014704)
0.1 12.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 550.5 GO:0031224 intrinsic component of membrane(GO:0031224)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 1.8 GO:0005652 nuclear lamina(GO:0005652)
0.1 6.2 GO:0031514 motile cilium(GO:0031514)
0.1 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 4.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.4 GO:0005861 troponin complex(GO:0005861)
0.1 3.2 GO:0071565 nBAF complex(GO:0071565)
0.1 75.8 GO:0005615 extracellular space(GO:0005615)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0035859 Seh1-associated complex(GO:0035859)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 33.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
7.8 31.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
7.0 49.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
5.8 23.2 GO:0097001 ceramide binding(GO:0097001)
5.6 16.7 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
5.5 32.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
4.8 14.5 GO:0017129 triglyceride binding(GO:0017129)
4.5 13.5 GO:0005137 interleukin-5 receptor binding(GO:0005137)
4.0 19.9 GO:0070097 delta-catenin binding(GO:0070097)
3.9 11.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
3.9 46.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.8 11.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
3.8 18.9 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
3.8 226.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
3.7 15.0 GO:0004802 transketolase activity(GO:0004802)
3.6 32.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
3.6 10.9 GO:0030350 iron-responsive element binding(GO:0030350)
3.6 14.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
3.6 18.1 GO:0004803 transposase activity(GO:0004803)
3.5 10.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
3.4 23.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.3 6.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
3.3 9.8 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
3.2 13.0 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
3.2 48.1 GO:0005344 oxygen transporter activity(GO:0005344)
3.2 12.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
3.2 12.7 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
3.1 18.3 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
3.1 9.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.9 14.7 GO:0004994 somatostatin receptor activity(GO:0004994)
2.9 11.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
2.9 67.6 GO:0051787 misfolded protein binding(GO:0051787)
2.9 11.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.9 34.6 GO:0008430 selenium binding(GO:0008430)
2.9 17.1 GO:0008420 CTD phosphatase activity(GO:0008420)
2.8 8.5 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
2.8 8.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.8 8.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
2.8 30.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.8 5.5 GO:0071723 lipopeptide binding(GO:0071723)
2.7 10.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
2.7 16.2 GO:0030172 troponin C binding(GO:0030172)
2.7 2.7 GO:0042289 MHC class II protein binding(GO:0042289)
2.6 102.8 GO:0042605 peptide antigen binding(GO:0042605)
2.6 15.6 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
2.6 15.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
2.6 36.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
2.6 12.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.6 15.4 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.5 7.6 GO:0004912 interleukin-3 receptor activity(GO:0004912)
2.5 20.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
2.5 7.5 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
2.4 7.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
2.4 14.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
2.4 14.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.3 23.2 GO:0032027 myosin light chain binding(GO:0032027)
2.3 13.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
2.3 9.2 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
2.3 6.9 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
2.3 9.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.2 8.9 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.2 20.0 GO:0031685 adenosine receptor binding(GO:0031685)
2.2 6.6 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
2.2 8.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
2.1 6.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
2.1 6.4 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
2.1 2.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
2.1 8.4 GO:0033897 ribonuclease T2 activity(GO:0033897)
2.1 6.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
2.1 14.5 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
2.0 8.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
2.0 6.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
2.0 2.0 GO:0080084 RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
2.0 8.0 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
2.0 9.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
2.0 7.9 GO:0051380 norepinephrine binding(GO:0051380)
2.0 3.9 GO:0070052 collagen V binding(GO:0070052)
1.9 7.7 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.9 7.7 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
1.9 7.6 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
1.9 5.7 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.9 5.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.9 3.7 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
1.9 3.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.8 7.4 GO:0004341 gluconolactonase activity(GO:0004341)
1.8 7.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.8 10.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.8 7.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
1.8 10.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.8 3.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.8 10.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.8 8.8 GO:0004995 tachykinin receptor activity(GO:0004995)
1.8 1.8 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
1.7 5.2 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
1.7 6.9 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.7 8.6 GO:0016841 ammonia-lyase activity(GO:0016841)
1.7 12.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.7 15.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.7 17.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.7 6.8 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.7 15.3 GO:0035174 histone serine kinase activity(GO:0035174)
1.7 8.4 GO:0008410 CoA-transferase activity(GO:0008410)
1.7 15.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.7 6.7 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
1.7 5.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.7 16.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
1.7 16.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
1.6 6.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
1.6 3.2 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
1.6 3.2 GO:0038064 collagen receptor activity(GO:0038064)
1.6 19.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.6 6.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.6 4.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
1.6 4.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
1.6 11.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.6 17.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
1.6 17.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.5 4.6 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
1.5 19.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
1.5 3.0 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.5 6.0 GO:0061714 folic acid receptor activity(GO:0061714)
1.5 13.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.5 4.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.5 13.5 GO:0043426 MRF binding(GO:0043426)
1.5 17.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
1.5 13.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.4 13.0 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
1.4 5.8 GO:0035473 lipase binding(GO:0035473)
1.4 5.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.4 2.9 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.4 4.3 GO:0008502 melatonin receptor activity(GO:0008502)
1.4 5.7 GO:0004773 steryl-sulfatase activity(GO:0004773)
1.4 29.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
1.4 8.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.4 5.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.4 11.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.4 6.9 GO:0070051 fibrinogen binding(GO:0070051)
1.4 6.9 GO:0070573 metallodipeptidase activity(GO:0070573)
1.4 6.9 GO:0031893 vasopressin receptor binding(GO:0031893)
1.4 1.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.3 4.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.3 10.8 GO:0097643 amylin receptor activity(GO:0097643)
1.3 9.4 GO:0004797 thymidine kinase activity(GO:0004797)
1.3 8.0 GO:0004359 glutaminase activity(GO:0004359)
1.3 37.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.3 14.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.3 6.6 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.3 5.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
1.3 5.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
1.3 6.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.3 6.4 GO:0042610 CD8 receptor binding(GO:0042610)
1.3 31.9 GO:0070300 phosphatidic acid binding(GO:0070300)
1.3 8.9 GO:0008172 S-methyltransferase activity(GO:0008172)
1.3 5.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.3 6.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.3 7.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.2 6.2 GO:0004522 ribonuclease A activity(GO:0004522)
1.2 4.9 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
1.2 3.7 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.2 6.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.2 3.6 GO:0045322 unmethylated CpG binding(GO:0045322)
1.2 3.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.2 3.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.2 10.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.2 4.7 GO:0047708 biotinidase activity(GO:0047708)
1.2 28.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.2 23.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.2 5.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.2 9.3 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
1.1 3.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.1 11.4 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 4.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.1 10.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.1 2.2 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
1.1 13.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.1 6.7 GO:0015057 thrombin receptor activity(GO:0015057)
1.1 6.6 GO:0090554 phosphatidylcholine transporter activity(GO:0008525) phosphatidylcholine-translocating ATPase activity(GO:0090554)
1.1 6.6 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
1.1 3.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
1.1 5.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.1 8.7 GO:0004645 phosphorylase activity(GO:0004645)
1.1 6.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.1 2.2 GO:0070405 ammonium ion binding(GO:0070405)
1.1 5.3 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.1 3.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.1 9.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
1.0 5.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.0 7.3 GO:0032395 MHC class II receptor activity(GO:0032395)
1.0 4.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.0 7.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.0 35.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
1.0 23.8 GO:0001223 transcription coactivator binding(GO:0001223)
1.0 8.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.0 13.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.0 4.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.0 6.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
1.0 138.4 GO:0003823 antigen binding(GO:0003823)
1.0 6.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.0 2.9 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
1.0 30.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.9 2.8 GO:0005042 netrin receptor activity(GO:0005042)
0.9 5.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.9 3.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.9 1.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.9 3.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.9 4.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.9 5.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.9 19.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.9 3.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.9 3.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.9 2.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.9 3.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.9 3.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 5.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.9 5.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.9 2.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.9 4.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.9 3.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.9 8.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.9 4.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.9 6.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.9 6.0 GO:0042608 T cell receptor binding(GO:0042608)
0.9 3.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.8 52.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 3.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.8 10.9 GO:0015926 glucosidase activity(GO:0015926)
0.8 2.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.8 9.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.8 3.3 GO:0000405 bubble DNA binding(GO:0000405)
0.8 25.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.8 12.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.8 3.2 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.8 6.5 GO:0045159 myosin II binding(GO:0045159)
0.8 13.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.8 7.2 GO:0016015 morphogen activity(GO:0016015)
0.8 3.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.8 9.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.8 2.4 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.8 4.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.8 25.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.8 3.9 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.8 3.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.8 3.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.8 4.6 GO:0004882 androgen receptor activity(GO:0004882)
0.8 8.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.8 2.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.8 3.0 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.7 2.2 GO:0001596 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.7 3.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.7 2.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.7 11.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.7 2.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.7 10.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.7 2.9 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.7 4.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.7 2.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.7 2.9 GO:0086077 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.7 10.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 10.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.7 2.1 GO:0033265 choline binding(GO:0033265)
0.7 4.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 3.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.7 2.8 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.7 9.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.7 8.3 GO:0045503 dynein light chain binding(GO:0045503)
0.7 2.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.7 4.8 GO:0045545 syndecan binding(GO:0045545)
0.7 20.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.7 24.0 GO:0030552 cAMP binding(GO:0030552)
0.7 8.9 GO:0070700 BMP receptor binding(GO:0070700)
0.7 6.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7 9.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7 3.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.7 10.2 GO:0035325 Toll-like receptor binding(GO:0035325)
0.7 8.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.7 6.0 GO:0010851 cyclase regulator activity(GO:0010851)
0.7 4.7 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
0.7 0.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.7 2.7 GO:0070411 I-SMAD binding(GO:0070411)
0.7 4.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.7 27.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.7 2.0 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.6 2.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.6 1.9 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.6 10.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 6.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.6 11.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.6 1.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.6 3.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.6 7.0 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 6.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.6 2.5 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.6 5.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.6 19.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 1.9 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.6 1.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 20.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.6 3.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.6 3.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.6 15.2 GO:0004707 MAP kinase activity(GO:0004707)
0.6 3.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.6 7.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.6 4.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 59.7 GO:0019905 syntaxin binding(GO:0019905)
0.6 1.8 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.6 7.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.6 11.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.6 6.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.6 4.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.6 5.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 4.6 GO:0004935 adrenergic receptor activity(GO:0004935)
0.6 1.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.6 4.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.6 2.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.6 3.4 GO:0017040 ceramidase activity(GO:0017040)
0.6 13.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.6 6.2 GO:0016594 glycine binding(GO:0016594)
0.6 7.9 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.6 5.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 2.8 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6 20.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.6 2.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.6 4.5 GO:0046625 sphingolipid binding(GO:0046625)
0.5 8.8 GO:0034452 dynactin binding(GO:0034452)
0.5 1.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.5 11.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5 4.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.5 1.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.5 15.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.5 8.5 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5 7.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.5 9.6 GO:0043274 phospholipase binding(GO:0043274)
0.5 1.6 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.5 2.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5 4.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.5 5.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 10.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.5 4.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 14.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 6.6 GO:0015643 toxic substance binding(GO:0015643)
0.5 5.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.5 2.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.5 3.0 GO:0001849 complement component C1q binding(GO:0001849)
0.5 4.0 GO:0046870 cadmium ion binding(GO:0046870)
0.5 3.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.5 2.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.5 34.7 GO:0070412 R-SMAD binding(GO:0070412)
0.5 5.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 1.0 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 12.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 6.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 1.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 8.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 1.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.5 7.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 6.8 GO:0016805 dipeptidase activity(GO:0016805)
0.5 1.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 3.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.5 7.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.5 5.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.5 100.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 3.7 GO:0015235 cobalamin transporter activity(GO:0015235)
0.5 3.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 14.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 1.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 1.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 6.3 GO:0019864 IgG binding(GO:0019864)
0.4 32.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 1.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 4.9 GO:0031433 telethonin binding(GO:0031433)
0.4 10.9 GO:0005521 lamin binding(GO:0005521)
0.4 1.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.4 1.3 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.4 3.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4 2.5 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.4 3.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.4 1.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.4 3.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.4 19.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.4 3.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 4.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 4.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.4 8.4 GO:0005112 Notch binding(GO:0005112)
0.4 19.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 1.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 7.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 1.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.4 10.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 1.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.4 6.8 GO:0070513 death domain binding(GO:0070513)
0.4 8.3 GO:0030275 LRR domain binding(GO:0030275)
0.4 6.0 GO:0031996 thioesterase binding(GO:0031996)
0.4 1.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 5.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 4.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.4 23.4 GO:0004497 monooxygenase activity(GO:0004497)
0.4 5.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 1.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 12.9 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.4 31.3 GO:0005179 hormone activity(GO:0005179)
0.4 2.8 GO:0050693 LBD domain binding(GO:0050693)
0.4 5.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.4 2.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 2.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 7.9 GO:0008066 glutamate receptor activity(GO:0008066)
0.3 9.0 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.3 1.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 3.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 2.0 GO:0051525 NFAT protein binding(GO:0051525)
0.3 7.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 1.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 2.3 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3 2.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 1.3 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.3 4.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3 1.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 2.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.6 GO:0043237 laminin-1 binding(GO:0043237)
0.3 18.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 30.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.9 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.3 1.9 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 4.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.3 7.1 GO:0031489 myosin V binding(GO:0031489)
0.3 2.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.3 5.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 1.8 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 2.1 GO:0034235 GPI anchor binding(GO:0034235)
0.3 4.8 GO:0000150 recombinase activity(GO:0000150)
0.3 26.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 5.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 1.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.3 21.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.3 2.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.3 2.6 GO:0004969 histamine receptor activity(GO:0004969)
0.3 10.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 2.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 6.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 2.3 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 8.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 5.1 GO:0038191 neuropilin binding(GO:0038191)
0.3 2.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 2.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 2.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.3 1.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 0.8 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.3 2.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.3 0.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 5.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 1.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 19.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.7 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 4.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 12.5 GO:0030507 spectrin binding(GO:0030507)
0.2 3.9 GO:0031005 filamin binding(GO:0031005)
0.2 1.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 7.3 GO:0032451 demethylase activity(GO:0032451)
0.2 0.7 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 2.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 3.2 GO:0015026 coreceptor activity(GO:0015026)
0.2 2.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 4.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 15.2 GO:0022843 voltage-gated cation channel activity(GO:0022843)
0.2 6.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 4.9 GO:0008494 translation activator activity(GO:0008494)
0.2 12.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 7.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 4.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 2.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 0.9 GO:0032052 bile acid binding(GO:0032052)
0.2 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 3.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 11.7 GO:0005518 collagen binding(GO:0005518)
0.2 0.6 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol pentakisphosphate phosphatase activity(GO:0052827) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.2 3.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 2.9 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 5.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 2.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2 5.2 GO:0017046 peptide hormone binding(GO:0017046)
0.2 2.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 3.4 GO:0097602 cullin family protein binding(GO:0097602)
0.2 9.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 2.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 1.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 5.8 GO:0017022 myosin binding(GO:0017022)
0.2 2.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 4.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.2 0.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 3.9 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.2 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 0.5 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 0.7 GO:0004905 type I interferon receptor activity(GO:0004905)
0.2 1.2 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 3.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 1.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 0.5 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 0.5 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 2.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 3.1 GO:0015276 ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.1 2.0 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.8 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.7 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.5 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 1.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 15.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.8 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 4.1 GO:0005109 frizzled binding(GO:0005109)
0.1 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 4.3 GO:0046934 phosphatidylinositol 3-kinase activity(GO:0035004) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 53.6 GO:0099600 transmembrane receptor activity(GO:0099600)
0.1 39.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.9 GO:0016918 retinal binding(GO:0016918)
0.1 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 146.4 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.3 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.1 GO:0003909 DNA ligase activity(GO:0003909)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.8 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 6.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.7 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703) beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.5 GO:0031404 chloride ion binding(GO:0031404)
0.0 6.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
1.1 9.0 PID S1P S1P3 PATHWAY S1P3 pathway
1.1 53.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.1 6.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
1.0 49.3 NABA COLLAGENS Genes encoding collagen proteins
0.9 15.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.8 79.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.8 35.4 ST GA12 PATHWAY G alpha 12 Pathway
0.7 54.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.7 22.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.7 6.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 37.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.6 8.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.6 28.1 PID RAS PATHWAY Regulation of Ras family activation
0.6 17.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.6 4.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.6 14.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.6 12.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.6 28.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.6 9.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 29.3 PID ARF6 PATHWAY Arf6 signaling events
0.5 25.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.5 10.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 13.8 PID EPO PATHWAY EPO signaling pathway
0.5 14.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 20.2 PID CD40 PATHWAY CD40/CD40L signaling
0.5 61.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 2.0 PID IL3 PATHWAY IL3-mediated signaling events
0.5 98.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.5 19.1 PID SHP2 PATHWAY SHP2 signaling
0.5 13.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 22.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 2.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 4.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.4 21.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 1.7 PID IL23 PATHWAY IL23-mediated signaling events
0.4 7.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.4 9.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 1.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.4 5.8 ST GA13 PATHWAY G alpha 13 Pathway
0.4 10.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 12.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 6.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 2.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4 3.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.4 22.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 1.8 PID IL27 PATHWAY IL27-mediated signaling events
0.3 19.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 8.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 2.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 21.0 PID BMP PATHWAY BMP receptor signaling
0.3 8.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 13.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 12.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.3 6.7 PID ENDOTHELIN PATHWAY Endothelins
0.3 7.9 PID INSULIN PATHWAY Insulin Pathway
0.3 1.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 71.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 2.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 3.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 6.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 5.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 1.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 4.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 37.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 6.3 PID BCR 5PATHWAY BCR signaling pathway
0.2 4.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 4.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 2.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 1.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.2 2.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 5.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 42.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.1 3.4 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.3 PID FGF PATHWAY FGF signaling pathway
0.1 2.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.7 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 99.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
3.3 33.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
2.8 52.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
2.8 30.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
1.7 35.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.6 40.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.6 38.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.5 41.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.5 6.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.5 20.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.4 22.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.4 2.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.4 6.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.3 21.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.2 17.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.1 105.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.1 54.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
1.1 21.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.0 16.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.0 39.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.0 2.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
1.0 10.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.0 29.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.0 9.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.0 19.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.9 29.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.9 6.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.9 5.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.9 12.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.9 34.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.9 14.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.9 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.9 13.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.9 17.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.8 11.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.8 3.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.8 15.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.8 12.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.8 6.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.8 5.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.8 7.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.8 2.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.7 32.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 16.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.7 5.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.7 24.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.7 14.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.7 19.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.7 29.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.7 11.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.7 29.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.7 24.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.6 5.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.6 30.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.6 9.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.6 7.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.6 19.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.6 12.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.6 272.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.6 32.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.6 17.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.6 13.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.6 34.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.6 11.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 24.2 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.6 8.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 5.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.5 1.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.5 3.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 6.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 133.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.5 16.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5 3.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 6.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5 16.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.5 13.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.5 6.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.5 1.9 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.5 34.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 5.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 7.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 9.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.4 3.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 8.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 6.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 6.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.4 6.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4 8.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.4 1.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.4 8.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 7.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 6.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 8.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.4 4.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.4 11.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 7.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.4 2.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.3 6.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 7.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 12.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 4.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 4.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.3 10.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 4.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 13.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.3 3.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 39.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 2.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 3.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 16.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 11.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 20.4 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.3 3.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 1.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3 3.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 13.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 6.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 3.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 9.1 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.2 25.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 3.3 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.2 4.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 3.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 3.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 4.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 1.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 3.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 2.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 2.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 0.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.6 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 8.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.1 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis