ISMARA results: LHX6

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for LHX6

Z-value: 1.66

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Transcription factors associated with LHX6

Gene Symbol	Gene ID	Gene Info
LHX6 Ensembl NCBI GeneCards UniProt	ENSG00000106852.15	LHX6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
LHX6	hg38_v1_chr9_-_122228845_122228967, hg38_v1_chr9_-_122227525_122227586	0.42	5.7e-11	Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr1_-_204411804 Show fit	10.93	ENST00000367188.5	PPP1R15B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 15B
chr14_+_99481395 Show fit	9.26	ENST00000389879.9 ENST00000557441.5 ENST00000555049.5 ENST00000555842.1	CCNK Ensembl NCBI GeneCards UniProt Show fit	cyclin K
chr12_-_91153149 Show fit	8.01	ENST00000550758.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr1_+_27935022 Show fit	7.96	ENST00000411604.5 ENST00000373888.8	SMPDL3B Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3B
chr6_-_166627244 Show fit	7.17	ENST00000265678.9	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr10_-_28282086 Show fit	6.85	ENST00000375719.7 ENST00000375732.5	MPP7 Ensembl NCBI GeneCards UniProt Show fit	membrane palmitoylated protein 7
chr10_-_97445850 Show fit	6.60	ENST00000477692.6 ENST00000485122.6 ENST00000370886.9 ENST00000370885.8 ENST00000370902.8 ENST00000370884.5	EXOSC1 Ensembl NCBI GeneCards UniProt Show fit	exosome component 1
chr17_+_76737387 Show fit	6.04	ENST00000590393.1 ENST00000355954.7 ENST00000586689.5 ENST00000587661.5 ENST00000593181.5 ENST00000336509.8	MFSD11 Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 11
chr12_-_44875647 Show fit	6.03	ENST00000395487.6	NELL2 Ensembl NCBI GeneCards UniProt Show fit	neural EGFL like 2
chr14_-_52069228 Show fit	5.99	ENST00000617139.4	NID2 Ensembl NCBI GeneCards UniProt Show fit	nidogen 2
chr14_-_52069039 Show fit	5.62	ENST00000216286.10	NID2 Ensembl NCBI GeneCards UniProt Show fit	nidogen 2
chr22_+_41381923 Show fit	5.55	ENST00000266304.9	TEF Ensembl NCBI GeneCards UniProt Show fit	TEF transcription factor, PAR bZIP family member
chr13_+_36431898 Show fit	5.42	ENST00000440264.5	CCNA1 Ensembl NCBI GeneCards UniProt Show fit	cyclin A1
chrX_-_47650488 Show fit	5.01	ENST00000247161.7 ENST00000376983.8 ENST00000343894.8	ELK1 Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ELK1
chr4_-_120922822 Show fit	4.96	ENST00000428209.6 ENST00000515109.5 ENST00000394435.2	PRDM5 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 5
chr19_-_19192122 Show fit	4.94	ENST00000444486.7 ENST00000514819.7 ENST00000585679.1 ENST00000462790.8	MEF2B Ensembl NCBI GeneCards UniProt Show fit BORCS8-MEF2B Ensembl NCBI GeneCards UniProt Show fit BORCS8 Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2B BORCS8-MEF2B readthrough BLOC-1 related complex subunit 8
chr20_-_37178966 Show fit	4.89	ENST00000422138.1	MROH8 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 8
chr12_-_44876294 Show fit	4.78	ENST00000429094.7 ENST00000551601.5 ENST00000549027.5 ENST00000452445.6	NELL2 Ensembl NCBI GeneCards UniProt Show fit	neural EGFL like 2
chr17_-_1628808 Show fit	4.76	ENST00000301335.10	SLC43A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 43 member 2
chr14_-_103715433 Show fit	4.69	ENST00000554913.5 ENST00000555055.6 ENST00000554974.5 ENST00000553361.5 ENST00000555964.5 ENST00000556682.5 ENST00000553332.5 ENST00000352127.11	XRCC3 Ensembl NCBI GeneCards UniProt Show fit	X-ray repair cross complementing 3
chr15_-_77420135 Show fit	4.52	ENST00000560626.6	PEAK1 Ensembl NCBI GeneCards UniProt Show fit	pseudopodium enriched atypical kinase 1
chr5_+_67004618 Show fit	4.45	ENST00000261569.11 ENST00000436277.5	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr15_-_77420087 Show fit	4.41	ENST00000564328.5 ENST00000682557.1 ENST00000558305.5	PEAK1 Ensembl NCBI GeneCards UniProt Show fit	pseudopodium enriched atypical kinase 1
chr11_+_76445001 Show fit	4.36	ENST00000533988.5 ENST00000524490.5 ENST00000334736.7 ENST00000533972.5	EMSY Ensembl NCBI GeneCards UniProt Show fit	EMSY transcriptional repressor, BRCA2 interacting
chr3_-_41961989 Show fit	4.25	ENST00000420927.5 ENST00000301831.9 ENST00000414606.1	ULK4 Ensembl NCBI GeneCards UniProt Show fit	unc-51 like kinase 4
chr10_-_102241502 Show fit	4.24	ENST00000370002.8	PITX3 Ensembl NCBI GeneCards UniProt Show fit	paired like homeodomain 3
chr14_+_103715767 Show fit	4.15	ENST00000311141.7	ZFYVE21 Ensembl NCBI GeneCards UniProt Show fit	zinc finger FYVE-type containing 21
chr9_-_92878018 Show fit	4.09	ENST00000332591.6 ENST00000375495.8 ENST00000395505.6 ENST00000395506.7	ZNF484 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 484
chr4_+_88592426 Show fit	4.06	ENST00000431413.5 ENST00000402738.6 ENST00000422770.5 ENST00000407637.5	HERC3 Ensembl NCBI GeneCards UniProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr14_+_103715724 Show fit	4.05	ENST00000216602.10	ZFYVE21 Ensembl NCBI GeneCards UniProt Show fit	zinc finger FYVE-type containing 21
chr17_-_46579651 Show fit	3.92	ENST00000573185.5 ENST00000570550.5 ENST00000445552.6 ENST00000329240.10 ENST00000622488.6 ENST00000336125.6	ARL17A Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 17A
chr6_-_31158073 Show fit	3.90	ENST00000507751.5 ENST00000448162.6 ENST00000502557.5 ENST00000503420.5 ENST00000507892.1 ENST00000507226.1 ENST00000513222.1 ENST00000503934.5 ENST00000396263.6 ENST00000508683.5 ENST00000428174.1 ENST00000448141.6 ENST00000507829.5 ENST00000455279.6 ENST00000376266.9	CCHCR1 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil alpha-helical rod protein 1
chrX_-_119943732 Show fit	3.90	ENST00000371410.5	NKAP Ensembl NCBI GeneCards UniProt Show fit	NFKB activating protein
chr3_-_105869035 Show fit	3.85	ENST00000447441.6 ENST00000403724.5 ENST00000405772.5	CBLB Ensembl NCBI GeneCards UniProt Show fit	Cbl proto-oncogene B
chr13_+_36432487 Show fit	3.60	ENST00000255465.7 ENST00000625767.1	CCNA1 Ensembl NCBI GeneCards UniProt Show fit	cyclin A1
chr2_-_201071579 Show fit	3.55	ENST00000453765.5 ENST00000452799.5 ENST00000446678.5 ENST00000418596.7 ENST00000681958.1	FAM126B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 126 member B
chr14_+_75661186 Show fit	3.54	ENST00000556977.5 ENST00000298832.14 ENST00000557636.5 ENST00000286650.9	TTLL5 Ensembl NCBI GeneCards UniProt Show fit	tubulin tyrosine ligase like 5
chr1_+_43650118 Show fit	3.51	ENST00000372396.4	KDM4A Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 4A
chr19_-_12722547 Show fit	3.49	ENST00000592287.5	TNPO2 Ensembl NCBI GeneCards UniProt Show fit	transportin 2
chr14_+_100376398 Show fit	3.47	ENST00000554998.5 ENST00000402312.8 ENST00000335290.10 ENST00000554175.5	WDR25 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 25
chr7_-_99679987 Show fit	3.36	ENST00000222982.8 ENST00000439761.3 ENST00000339843.6	CYP3A5 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 3 subfamily A member 5
chr1_-_92486916 Show fit	3.34	ENST00000294702.6	GFI1 Ensembl NCBI GeneCards UniProt Show fit	growth factor independent 1 transcriptional repressor
chr2_-_101308681 Show fit	3.33	ENST00000295317.4	RNF149 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 149
chr4_-_145180496 Show fit	3.26	ENST00000447906.8	OTUD4 Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase 4
chr19_+_17747698 Show fit	3.13	ENST00000594202.5 ENST00000252771.11	FCHO1 Ensembl NCBI GeneCards UniProt Show fit	FCH and mu domain containing endocytic adaptor 1
chr14_+_21825453 Show fit	3.11	ENST00000390432.2	TRAV10 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 10
chr17_-_46361718 Show fit	3.11	ENST00000575960.5 ENST00000575698.5 ENST00000571246.5 ENST00000434041.6 ENST00000656849.1 ENST00000570618.5 ENST00000450673.4 ENST00000622877.4	ARL17B Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 17B
chr22_-_21735744 Show fit	3.03	ENST00000403503.1	YPEL1 Ensembl NCBI GeneCards UniProt Show fit	yippee like 1
chr1_-_13285154 Show fit	2.99	ENST00000357367.6 ENST00000614831.1	PRAMEF8 Ensembl NCBI GeneCards UniProt Show fit	PRAME family member 8
chr10_-_70382589 Show fit	2.96	ENST00000373224.5 ENST00000446961.4 ENST00000357631.6 ENST00000358141.6 ENST00000395010.5	LRRC20 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 20
chr1_-_48400826 Show fit	2.95	ENST00000371841.1	SPATA6 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr6_-_62286161 Show fit	2.95	ENST00000281156.5	KHDRBS2 Ensembl NCBI GeneCards UniProt Show fit	KH RNA binding domain containing, signal transduction associated 2
chr2_-_151261839 Show fit	2.93	ENST00000331426.6	RBM43 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 43
chr1_+_100351698 Show fit	2.93	ENST00000644676.1	CDC14A Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr5_-_113294895 Show fit	2.92	ENST00000514701.5 ENST00000302475.8	MCC Ensembl NCBI GeneCards UniProt Show fit	MCC regulator of WNT signaling pathway
chr2_+_113005454 Show fit	2.90	ENST00000259211.7	IL36A Ensembl NCBI GeneCards UniProt Show fit	interleukin 36 alpha
chr4_+_94974984 Show fit	2.90	ENST00000672698.1	BMPR1B Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein receptor type 1B
chr7_+_100612372 Show fit	2.88	ENST00000493970.5	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr16_+_6483379 Show fit	2.81	ENST00000552089.5	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr12_+_6904733 Show fit	2.81	ENST00000007969.12 ENST00000622489.4 ENST00000443597.7 ENST00000323702.9	LRRC23 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 23
chr16_+_72054477 Show fit	2.76	ENST00000355906.10 ENST00000570083.5 ENST00000228226.12 ENST00000398131.6 ENST00000569639.5 ENST00000564499.5 ENST00000357763.8 ENST00000613898.1 ENST00000562526.5 ENST00000565574.5 ENST00000568417.6	HP Ensembl NCBI GeneCards UniProt Show fit	haptoglobin
chr19_+_17747737 Show fit	2.76	ENST00000600676.5 ENST00000600209.5 ENST00000596309.5 ENST00000598539.5 ENST00000597474.5 ENST00000593385.5 ENST00000598067.5 ENST00000593833.5	FCHO1 Ensembl NCBI GeneCards UniProt Show fit	FCH and mu domain containing endocytic adaptor 1
chr7_+_100612102 Show fit	2.70	ENST00000223054.8	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr6_-_27912396 Show fit	2.60	ENST00000303324.4	OR2B2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily B member 2
chr8_+_9555900 Show fit	2.59	ENST00000310430.11 ENST00000520408.5 ENST00000522110.1	TNKS Ensembl NCBI GeneCards UniProt Show fit	tankyrase
chr16_+_6483728 Show fit	2.56	ENST00000675459.1 ENST00000551752.5	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr6_-_119149124 Show fit	2.55	ENST00000368475.8	FAM184A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 184 member A
chr12_-_56360084 Show fit	2.53	ENST00000314128.9 ENST00000557235.5 ENST00000651915.1	STAT2 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 2
chr3_-_161105224 Show fit	2.43	ENST00000651254.1 ENST00000651178.1 ENST00000476999.6 ENST00000652596.1 ENST00000651305.1 ENST00000652111.1 ENST00000651292.1 ENST00000651282.1 ENST00000651380.1 ENST00000494173.7 ENST00000484127.5 ENST00000650733.1 ENST00000494818.6 ENST00000492353.5 ENST00000652143.1 ENST00000473142.5 ENST00000651147.1 ENST00000468268.5 ENST00000460353.2 ENST00000651953.1 ENST00000651972.1 ENST00000652730.1 ENST00000651460.1 ENST00000652059.1 ENST00000651509.1 ENST00000651801.1 ENST00000651686.1 ENST00000320474.10 ENST00000392781.7 ENST00000392779.6 ENST00000651791.1 ENST00000651117.1 ENST00000652032.1	B3GALNT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_-_129024157 Show fit	2.33	ENST00000392657.7	ARHGAP32 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 32
chr16_+_6483813 Show fit	2.33	ENST00000675653.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr5_-_55534955 Show fit	2.25	ENST00000307259.9 ENST00000264775.9	PLPP1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 1
chr1_+_12019460 Show fit	2.24	ENST00000235332.6	MIIP Ensembl NCBI GeneCards UniProt Show fit	migration and invasion inhibitory protein
chr12_-_95217373 Show fit	2.23	ENST00000549499.1 ENST00000546711.5 ENST00000343958.9	FGD6 Ensembl NCBI GeneCards UniProt Show fit	FYVE, RhoGEF and PH domain containing 6
chr1_-_145996567 Show fit	2.23	ENST00000582401.6	TXNIP Ensembl NCBI GeneCards UniProt Show fit	thioredoxin interacting protein
chr3_-_99850976 Show fit	2.20	ENST00000487087.5	FILIP1L Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1 like
chr10_-_97687191 Show fit	2.19	ENST00000370626.4	AVPI1 Ensembl NCBI GeneCards UniProt Show fit	arginine vasopressin induced 1
chr20_-_64049631 Show fit	2.18	ENST00000340356.9	SOX18 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 18
chr10_-_121515179 Show fit	2.17	ENST00000429361.5	FGFR2 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor receptor 2
chr18_-_69956924 Show fit	2.15	ENST00000581982.5 ENST00000280200.8	CD226 Ensembl NCBI GeneCards UniProt Show fit	CD226 molecule
chr1_+_15659869 Show fit	2.15	ENST00000345034.1	RSC1A1 Ensembl NCBI GeneCards UniProt Show fit	regulator of solute carriers 1
chr19_-_41363930 Show fit	2.15	ENST00000675972.1	B9D2 Ensembl NCBI GeneCards UniProt Show fit	B9 domain containing 2
chr12_+_51951663 Show fit	2.14	ENST00000257963.9 ENST00000541224.5 ENST00000426655.6 ENST00000536420.5 ENST00000415850.6	ACVR1B Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1B
chr21_-_37267511 Show fit	2.11	ENST00000398998.1	VPS26C Ensembl NCBI GeneCards UniProt Show fit	VPS26 endosomal protein sorting factor C
chr4_+_70430487 Show fit	2.10	ENST00000413702.5	MUC7 Ensembl NCBI GeneCards UniProt Show fit	mucin 7, secreted
chrX_+_136205982 Show fit	2.07	ENST00000628568.1	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr22_-_21735776 Show fit	2.05	ENST00000339468.8	YPEL1 Ensembl NCBI GeneCards UniProt Show fit	yippee like 1
chrX_-_154097731 Show fit	2.05	ENST00000628176.2	MECP2 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding protein 2
chr3_-_161105399 Show fit	2.03	ENST00000652593.1	B3GALNT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr19_-_40413364 Show fit	1.95	ENST00000291825.11 ENST00000324001.8	PRX Ensembl NCBI GeneCards UniProt Show fit	periaxin
chr2_+_90038848 Show fit	1.95	ENST00000390270.2	IGKV3D-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr12_+_6904962 Show fit	1.93	ENST00000415834.5 ENST00000436789.5	LRRC23 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 23
chr11_-_236326 Show fit	1.91	ENST00000525237.1 ENST00000382743.9 ENST00000532956.5 ENST00000525319.5 ENST00000524564.5	SIRT3 Ensembl NCBI GeneCards UniProt Show fit	sirtuin 3
chr2_-_89010515 Show fit	1.89	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr6_+_160121809 Show fit	1.86	ENST00000366963.9	SLC22A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 1
chr1_-_236065079 Show fit	1.86	ENST00000264187.7 ENST00000366595.7	NID1 Ensembl NCBI GeneCards UniProt Show fit	nidogen 1
chr14_+_32329341 Show fit	1.78	ENST00000557354.5 ENST00000557102.1 ENST00000557272.1	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 6
chr11_-_35265696 Show fit	1.78	ENST00000464522.2	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr5_-_20575850 Show fit	1.77	ENST00000507958.5	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18
chr1_+_241532370 Show fit	1.76	ENST00000366559.9 ENST00000366557.8	KMO Ensembl NCBI GeneCards UniProt Show fit	kynurenine 3-monooxygenase
chr19_-_41364119 Show fit	1.76	ENST00000243578.8	B9D2 Ensembl NCBI GeneCards UniProt Show fit	B9 domain containing 2
chr18_-_23437927 Show fit	1.75	ENST00000578520.5 ENST00000383233.8	TMEM241 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 241
chr7_-_87713287 Show fit	1.75	ENST00000416177.1 ENST00000265724.8 ENST00000543898.5	ABCB1 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily B member 1
chr3_+_108822778 Show fit	1.69	ENST00000295756.11	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chrX_+_15507302 Show fit	1.68	ENST00000342014.6	BMX Ensembl NCBI GeneCards UniProt Show fit	BMX non-receptor tyrosine kinase
chr19_-_10010492 Show fit	1.68	ENST00000264828.4	COL5A3 Ensembl NCBI GeneCards UniProt Show fit	collagen type V alpha 3 chain
chr20_+_56392607 Show fit	1.67	ENST00000217109.9 ENST00000452950.1	CSTF1 Ensembl NCBI GeneCards UniProt Show fit	cleavage stimulation factor subunit 1
chr8_-_42768602 Show fit	1.66	ENST00000534622.5	CHRNA6 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 6 subunit
chr2_+_165239432 Show fit	1.65	ENST00000636071.2 ENST00000636985.2	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr17_+_75456618 Show fit	1.65	ENST00000314256.12 ENST00000582186.5 ENST00000582455.5 ENST00000581252.5 ENST00000579208.5	TMEM94 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 94
chr16_-_66550142 Show fit	1.63	ENST00000417693.8 ENST00000299697.12 ENST00000451102.7	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2
chr16_-_55833085 Show fit	1.61	ENST00000360526.8	CES1 Ensembl NCBI GeneCards UniProt Show fit	carboxylesterase 1
chr1_-_12848720 Show fit	1.61	ENST00000317869.7	HNRNPCL1 Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein C like 1
chr7_+_100612522 Show fit	1.60	ENST00000393950.7 ENST00000424091.2	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr2_+_165239388 Show fit	1.59	ENST00000424833.5 ENST00000375437.7 ENST00000631182.3	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr5_+_161850597 Show fit	1.59	ENST00000634335.1 ENST00000635880.1	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr3_+_108822759 Show fit	1.59	ENST00000426646.1	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chr6_+_27815010 Show fit	1.58	ENST00000621112.2	H2BC14 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 14
chr3_-_161105070 Show fit	1.57	ENST00000651430.1 ENST00000650695.1 ENST00000651689.1 ENST00000651916.1 ENST00000488170.5 ENST00000652377.1 ENST00000652669.1	B3GALNT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr12_+_27524151 Show fit	1.53	ENST00000545334.5 ENST00000540114.5 ENST00000537927.5 ENST00000228425.11 ENST00000318304.12 ENST00000535047.5 ENST00000542629.5	PPFIBP1 Ensembl NCBI GeneCards UniProt Show fit	PPFIA binding protein 1
chr22_-_41621014 Show fit	1.53	ENST00000263256.7	DESI1 Ensembl NCBI GeneCards UniProt Show fit	desumoylating isopeptidase 1
chr19_+_35748549 Show fit	1.53	ENST00000301159.14	LIN37 Ensembl NCBI GeneCards UniProt Show fit	lin-37 DREAM MuvB core complex component
chr10_+_69802424 Show fit	1.52	ENST00000673802.2 ENST00000517713.5 ENST00000520133.5 ENST00000522165.5 ENST00000673641.2 ENST00000673628.2	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr14_+_32329256 Show fit	1.52	ENST00000280979.9	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 6
chr6_+_26402289 Show fit	1.51	ENST00000414912.2	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A1
chr6_+_52186373 Show fit	1.50	ENST00000648244.1	IL17A Ensembl NCBI GeneCards UniProt Show fit	interleukin 17A
chr7_+_100612430 Show fit	1.48	ENST00000379527.6	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr16_-_66550005 Show fit	1.47	ENST00000527284.6	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2
chr6_-_27814757 Show fit	1.41	ENST00000333151.5	H2AC14 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 14
chr1_-_115089414 Show fit	1.39	ENST00000433172.3 ENST00000369515.6 ENST00000369516.7	TSPAN2 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 2
chr11_-_101129806 Show fit	1.38	ENST00000325455.10 ENST00000617858.4 ENST00000619228.2	PGR Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor
chr1_-_173917281 Show fit	1.38	ENST00000367698.4	SERPINC1 Ensembl NCBI GeneCards UniProt Show fit	serpin family C member 1
chr11_+_33039996 Show fit	1.37	ENST00000432887.5 ENST00000528898.1 ENST00000531632.6	TCP11L1 Ensembl NCBI GeneCards UniProt Show fit	t-complex 11 like 1
chr4_+_77605807 Show fit	1.34	ENST00000682537.1	CXCL13 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 13
chr12_-_9607903 Show fit	1.32	ENST00000229402.4	KLRB1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor B1
chr13_+_33016415 Show fit	1.32	ENST00000380099.4	KL Ensembl NCBI GeneCards UniProt Show fit	klotho
chr17_+_82458174 Show fit	1.31	ENST00000579198.5 ENST00000390006.8 ENST00000580296.5	NARF Ensembl NCBI GeneCards UniProt Show fit	nuclear prelamin A recognition factor
chr17_-_64130813 Show fit	1.29	ENST00000606895.2	ERN1 Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum to nucleus signaling 1
chr16_-_66550091 Show fit	1.27	ENST00000564917.5 ENST00000677420.1	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2
chr3_-_105868964 Show fit	1.24	ENST00000394030.8	CBLB Ensembl NCBI GeneCards UniProt Show fit	Cbl proto-oncogene B
chr1_+_27934980 Show fit	1.23	ENST00000373894.8	SMPDL3B Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3B
chr1_+_151762899 Show fit	1.23	ENST00000635322.1 ENST00000321531.10	OAZ3 Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 3
chr6_+_63635792 Show fit	1.22	ENST00000262043.8 ENST00000506783.5 ENST00000481385.6 ENST00000515594.5 ENST00000494284.6	PHF3 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 3
chr17_-_79797030 Show fit	1.21	ENST00000269385.9	CBX8 Ensembl NCBI GeneCards UniProt Show fit	chromobox 8
chrX_-_154097668 Show fit	1.21	ENST00000407218.5 ENST00000303391.11 ENST00000453960.7	MECP2 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding protein 2
chr9_+_101398841 Show fit	1.19	ENST00000339664.7 ENST00000374861.7 ENST00000259395.4 ENST00000615466.1	ZNF189 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 189
chrX_+_101098165 Show fit	1.17	ENST00000684367.1 ENST00000423383.3 ENST00000682304.1 ENST00000682095.1 ENST00000403304.6 ENST00000435570.1	CENPI Ensembl NCBI GeneCards UniProt Show fit	centromere protein I
chr9_-_125143457 Show fit	1.16	ENST00000373549.8 ENST00000336505.11	SCAI Ensembl NCBI GeneCards UniProt Show fit	suppressor of cancer cell invasion
chrX_+_30243715 Show fit	1.16	ENST00000378981.8 ENST00000397550.6	MAGEB1 Ensembl NCBI GeneCards UniProt Show fit	MAGE family member B1
chr19_+_49487510 Show fit	1.14	ENST00000679106.1 ENST00000621674.4 ENST00000391857.9 ENST00000678510.1 ENST00000467825.2	RPL13A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L13a
chr5_+_177426667 Show fit	1.13	ENST00000355472.10	GRK6 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor kinase 6
chr6_+_159761991 Show fit	1.08	ENST00000367048.5	ACAT2 Ensembl NCBI GeneCards UniProt Show fit	acetyl-CoA acetyltransferase 2
chr7_-_151633182 Show fit	1.07	ENST00000476632.2	PRKAG2 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit gamma 2
chr17_-_42185452 Show fit	1.04	ENST00000293330.1	HCRT Ensembl NCBI GeneCards UniProt Show fit	hypocretin neuropeptide precursor
chr1_+_27935110 Show fit	1.04	ENST00000549094.1	SMPDL3B Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3B
chr4_+_164754116 Show fit	1.02	ENST00000507311.1	SMIM31 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 31
chr17_-_48968587 Show fit	1.01	ENST00000357424.2	GIP Ensembl NCBI GeneCards UniProt Show fit	gastric inhibitory polypeptide
chr11_+_77821125 Show fit	1.01	ENST00000526415.5 ENST00000393427.6 ENST00000527134.5 ENST00000304716.12 ENST00000630098.2	AAMDC Ensembl NCBI GeneCards UniProt Show fit	adipogenesis associated Mth938 domain containing
chr16_-_66549839 Show fit	1.01	ENST00000527800.6 ENST00000677555.1 ENST00000563369.6	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2
chr10_+_69801892 Show fit	0.99	ENST00000398978.8 ENST00000645393.2 ENST00000354547.7 ENST00000674121.1 ENST00000673842.1 ENST00000520267.5	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr1_+_12857086 Show fit	0.98	ENST00000240189.2	PRAMEF2 Ensembl NCBI GeneCards UniProt Show fit	PRAME family member 2
chr5_-_9712200 Show fit	0.97	ENST00000506620.1 ENST00000514078.1 ENST00000606744.1	TAS2R1 Ensembl NCBI GeneCards UniProt Show fit LINC02112 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 1 long intergenic non-protein coding RNA 2112
chr11_+_77821187 Show fit	0.97	ENST00000525409.5	AAMDC Ensembl NCBI GeneCards UniProt Show fit	adipogenesis associated Mth938 domain containing
chr13_-_19181773 Show fit	0.93	ENST00000618094.1 ENST00000400113.8	TUBA3C Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 3c
chrX_+_114584037 Show fit	0.93	ENST00000371951.5 ENST00000371950.3 ENST00000276198.6	HTR2C Ensembl NCBI GeneCards UniProt Show fit	5-hydroxytryptamine receptor 2C
chr19_+_39125769 Show fit	0.90	ENST00000602004.1 ENST00000599470.5 ENST00000321944.8 ENST00000593480.5 ENST00000358301.7 ENST00000593690.5 ENST00000599386.5	PAK4 Ensembl NCBI GeneCards UniProt Show fit	p21 (RAC1) activated kinase 4
chr18_+_616672 Show fit	0.89	ENST00000338387.11	CLUL1 Ensembl NCBI GeneCards UniProt Show fit	clusterin like 1
chr11_-_101129706 Show fit	0.89	ENST00000534013.5	PGR Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor
chr6_-_30617232 Show fit	0.88	ENST00000376511.7	PPP1R10 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 10
chr7_-_13989891 Show fit	0.86	ENST00000405218.6	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr10_+_69801874 Show fit	0.84	ENST00000357811.8	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr7_-_83162857 Show fit	0.83	ENST00000333891.14	PCLO Ensembl NCBI GeneCards UniProt Show fit	piccolo presynaptic cytomatrix protein
chr17_-_42676980 Show fit	0.83	ENST00000587627.1 ENST00000591022.6 ENST00000293349.10	PLEKHH3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology, MyTH4 and FERM domain containing H3
chr11_+_60088657 Show fit	0.81	ENST00000617306.1 ENST00000278888.8	MS4A2 Ensembl NCBI GeneCards UniProt Show fit	membrane spanning 4-domains A2
chr15_+_40405787 Show fit	0.80	ENST00000610693.5 ENST00000479013.7 ENST00000487418.8	IVD Ensembl NCBI GeneCards UniProt Show fit	isovaleryl-CoA dehydrogenase
chr20_-_52105644 Show fit	0.80	ENST00000371523.8	ZFP64 Ensembl NCBI GeneCards UniProt Show fit	ZFP64 zinc finger protein
chr17_-_81656532 Show fit	0.78	ENST00000331056.10	PDE6G Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 6G
chr1_+_241532121 Show fit	0.78	ENST00000366558.7	KMO Ensembl NCBI GeneCards UniProt Show fit	kynurenine 3-monooxygenase
chr1_-_228425350 Show fit	0.77	ENST00000366696.2	H3-4 Ensembl NCBI GeneCards UniProt Show fit	H3.4 histone
chr11_-_55936400 Show fit	0.77	ENST00000301532.3	OR5I1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily I member 1
chr6_-_110179995 Show fit	0.75	ENST00000392586.5 ENST00000419252.1 ENST00000359451.6 ENST00000392588.5	WASF1 Ensembl NCBI GeneCards UniProt Show fit	WASP family member 1
chr3_-_151316795 Show fit	0.74	ENST00000260843.5	GPR87 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 87
chr12_-_52652207 Show fit	0.70	ENST00000309680.4	KRT2 Ensembl NCBI GeneCards UniProt Show fit	keratin 2
chr2_+_105241743 Show fit	0.68	ENST00000258456.3	GPR45 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 45
chr17_-_49764123 Show fit	0.66	ENST00000240364.7 ENST00000506156.1	FAM117A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 117 member A
chr9_+_133636355 Show fit	0.66	ENST00000393056.8	DBH Ensembl NCBI GeneCards UniProt Show fit	dopamine beta-hydroxylase
chr1_-_158426237 Show fit	0.65	ENST00000641042.1	OR10K2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily K member 2
chr6_+_26402237 Show fit	0.64	ENST00000476549.6 ENST00000450085.6 ENST00000425234.6 ENST00000427334.5 ENST00000506698.1 ENST00000289361.11	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 3 member A1
chr5_+_142770367 Show fit	0.61	ENST00000645722.2 ENST00000274498.9	ARHGAP26 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 26
chr3_+_63819341 Show fit	0.60	ENST00000647022.1	C3orf49 Ensembl NCBI GeneCards UniProt Show fit	chromosome 3 open reading frame 49
chr1_-_152414256 Show fit	0.57	ENST00000271835.3	CRNN Ensembl NCBI GeneCards UniProt Show fit	cornulin
chr13_-_46052712 Show fit	0.57	ENST00000242848.8 ENST00000679008.1 ENST00000282007.7	ZC3H13 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 13
chr22_-_38794111 Show fit	0.56	ENST00000406622.5 ENST00000216068.9 ENST00000406199.3	SUN2 Ensembl NCBI GeneCards UniProt Show fit DNAL4 Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 2 dynein axonemal light chain 4
chr5_-_83673544 Show fit	0.54	ENST00000503117.1 ENST00000510978.5	HAPLN1 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan and proteoglycan link protein 1
chr17_+_82458649 Show fit	0.54	ENST00000345415.11 ENST00000412079.6 ENST00000457415.7 ENST00000584411.5 ENST00000577432.5	NARF Ensembl NCBI GeneCards UniProt Show fit	nuclear prelamin A recognition factor
chr6_-_26271815 Show fit	0.51	ENST00000614378.1	H3C8 Ensembl NCBI GeneCards UniProt Show fit	H3 clustered histone 8
chr5_+_174724549 Show fit	0.50	ENST00000239243.7 ENST00000507785.2	MSX2 Ensembl NCBI GeneCards UniProt Show fit	msh homeobox 2
chr6_-_155455830 Show fit	0.48	ENST00000159060.3	NOX3 Ensembl NCBI GeneCards UniProt Show fit	NADPH oxidase 3
chr13_-_26221703 Show fit	0.44	ENST00000381570.7 ENST00000346166.7	RNF6 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 6
chr14_-_75660816 Show fit	0.42	ENST00000256319.7	ERG28 Ensembl NCBI GeneCards UniProt Show fit	ergosterol biosynthesis 28 homolog

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	9.3	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
1.6	4.7	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.4	4.2	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
1.2	10.9	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.1	6.9	GO:0071896	protein localization to adherens junction(GO:0071896)
1.1	3.3	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.1	3.3	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.9	10.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.9	2.8	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.9	5.4	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.9	2.6	GO:0099403	negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) protein auto-ADP-ribosylation(GO:0070213) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of telomeric DNA binding(GO:1904742) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.8	2.5	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.8	3.4	GO:0009822	alkaloid catabolic process(GO:0009822)
0.8	10.8	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.7	2.2	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.6	8.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6	1.7	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.6	2.3	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.6	3.3	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5	3.3	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.5	2.2	GO:0048865	stem cell fate commitment(GO:0048865)
0.5	2.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.5	3.5	GO:0018095	protein polyglutamylation(GO:0018095)
0.5	3.5	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.5	5.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.4	1.3	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4	2.9	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.4	1.2	GO:0015847	putrescine transport(GO:0015847)
0.4	13.5	GO:0071711	basement membrane organization(GO:0071711)
0.4	2.2	GO:0035603	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.3	9.0	GO:0007141	male meiosis I(GO:0007141)
0.3	1.5	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.3	1.7	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.3	0.8	GO:0098928	presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3	1.9	GO:0048241	epinephrine transport(GO:0048241)
0.3	8.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.3	6.0	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.3	1.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.3	2.3	GO:0008354	germ cell migration(GO:0008354)
0.2	3.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2	1.4	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2	1.3	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2	0.4	GO:0090269	fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.2	5.9	GO:0048268	clathrin coat assembly(GO:0048268)
0.2	0.9	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2	4.2	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.2	2.9	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.2	1.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	5.0	GO:0051567	histone H3-K9 methylation(GO:0051567)
0.2	1.9	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	1.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	1.6	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.1	5.8	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	1.7	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	8.2	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	6.5	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.1	0.5	GO:0090427	embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1	3.9	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	1.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	0.6	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.1	0.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	3.0	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.7	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1	0.7	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.1	3.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	2.2	GO:0002347	response to tumor cell(GO:0002347)
0.1	0.5	GO:0048840	otolith development(GO:0048840)
0.1	2.2	GO:0072643	interferon-gamma secretion(GO:0072643)
0.1	2.5	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.1	5.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.8	GO:0006552	leucine catabolic process(GO:0006552)
0.1	1.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	5.0	GO:0030574	collagen catabolic process(GO:0030574)
0.1	1.4	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.1	3.0	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1	1.6	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.3	GO:0040030	regulation of molecular function, epigenetic(GO:0040030)
0.1	0.4	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	6.5	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	1.2	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	1.1	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.9	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.7	GO:0051546	keratinocyte migration(GO:0051546)
0.0	3.9	GO:0006611	protein export from nucleus(GO:0006611)
0.0	1.7	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	2.9	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.3	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.7	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	2.9	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	2.1	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0	3.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	3.3	GO:0035690	cellular response to drug(GO:0035690)
0.0	2.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	1.0	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.2	GO:0035904	aorta development(GO:0035904)
0.0	2.2	GO:0046847	filopodium assembly(GO:0046847)
0.0	2.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.3	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0	3.8	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.3	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.0	0.8	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0	2.2	GO:0030336	negative regulation of cell migration(GO:0030336)
0.0	1.8	GO:0034332	adherens junction organization(GO:0034332)
0.0	5.5	GO:0048511	rhythmic process(GO:0048511)
0.0	0.2	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.0	1.1	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	2.0	GO:0008366	ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0	0.4	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.0	0.9	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	6.9	GO:0007507	heart development(GO:0007507)
0.0	0.5	GO:0014047	glutamate secretion(GO:0014047)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	9.3	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
2.3	9.0	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
1.1	3.4	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.0	3.0	GO:0097224	sperm connecting piece(GO:0097224)
0.8	4.7	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7	2.1	GO:0097679	other organism cytoplasm(GO:0097679)
0.7	2.8	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.6	10.9	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.6	8.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6	1.7	GO:0005588	collagen type V trimer(GO:0005588)
0.5	2.1	GO:0048179	activin receptor complex(GO:0048179)
0.5	6.6	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.4	1.3	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.4	2.9	GO:0060091	kinocilium(GO:0060091)
0.4	3.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3	6.9	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.3	0.8	GO:0099569	cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.2	2.9	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	3.9	GO:0036038	MKS complex(GO:0036038)
0.2	1.8	GO:0005638	lamin filament(GO:0005638)
0.2	3.2	GO:0033270	paranode region of axon(GO:0033270)
0.2	3.5	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	3.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	2.6	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.1	GO:0097452	GAIT complex(GO:0097452)
0.1	0.9	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	13.7	GO:0005604	basement membrane(GO:0005604)
0.1	1.2	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.7	GO:0042584	chromaffin granule membrane(GO:0042584)
0.1	9.8	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.7	GO:0031209	SCAR complex(GO:0031209)
0.1	1.7	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	5.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.0	1.8	GO:0030673	axolemma(GO:0030673)
0.0	0.6	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	1.6	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	4.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	5.2	GO:0030027	lamellipodium(GO:0030027)
0.0	5.0	GO:0043679	axon terminus(GO:0043679)
0.0	0.8	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	3.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	3.1	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.7	GO:0045095	keratin filament(GO:0045095)
0.0	11.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.5	GO:0048786	presynaptic active zone(GO:0048786)
0.0	4.5	GO:0060076	excitatory synapse(GO:0060076)
0.0	1.7	GO:0032587	ruffle membrane(GO:0032587)
0.0	3.3	GO:0005802	trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.2	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
1.2	6.0	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.1	10.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.8	5.4	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.7	3.5	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.7	4.7	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.6	1.7	GO:0036080	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.6	1.7	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.5	1.9	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.4	1.3	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.4	9.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4	2.9	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.4	1.2	GO:0015203	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.4	2.8	GO:0030492	hemoglobin binding(GO:0030492)
0.4	5.9	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.4	2.3	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4	3.3	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.4	2.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.3	1.6	GO:0004771	sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3	1.9	GO:0043237	laminin-1 binding(GO:0043237)
0.3	3.0	GO:0032027	myosin light chain binding(GO:0032027)
0.3	1.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3	1.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.3	3.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2	2.5	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.2	3.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2	1.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.2	3.9	GO:0043495	protein anchor(GO:0043495)
0.2	2.9	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	2.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	1.6	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2	21.3	GO:0005518	collagen binding(GO:0005518)
0.2	3.4	GO:0070330	aromatase activity(GO:0070330)
0.1	6.6	GO:0004532	exoribonuclease activity(GO:0004532)
0.1	1.8	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	4.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	4.8	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	0.7	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	3.9	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	9.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.8	GO:0019863	IgE binding(GO:0019863)
0.1	1.2	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	11.8	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	3.0	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	3.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	3.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	1.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.9	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1	1.8	GO:0005521	lamin binding(GO:0005521)
0.1	0.8	GO:0005549	odorant binding(GO:0005549)
0.1	3.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	1.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	5.1	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1	0.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	1.7	GO:0042166	acetylcholine binding(GO:0042166)
0.1	6.5	GO:0035591	signaling adaptor activity(GO:0035591)
0.1	0.3	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.1	0.3	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1	2.9	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	28.5	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0	0.8	GO:0005522	profilin binding(GO:0005522)
0.0	0.8	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.7	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	2.2	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	3.3	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	2.9	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.9	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	7.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	1.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	2.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	5.5	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	4.4	GO:0000287	magnesium ion binding(GO:0000287)
0.0	2.9	GO:0008201	heparin binding(GO:0008201)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	2.2	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	3.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.5	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	2.1	GO:0044325	ion channel binding(GO:0044325)
0.0	0.8	GO:0030507	spectrin binding(GO:0030507)
0.0	1.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.2	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	7.9	GO:0005509	calcium ion binding(GO:0005509)
0.0	4.2	GO:0004674	protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	13.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.3	1.7	PID BARD1 PATHWAY	BARD1 signaling events
0.2	5.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	13.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.2	8.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	5.0	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	1.6	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	2.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	4.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	5.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	2.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	1.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	2.9	PID BMP PATHWAY	BMP receptor signaling
0.0	8.1	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.8	PID FGF PATHWAY	FGF signaling pathway
0.0	1.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	4.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	3.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	2.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.8	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	1.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	2.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.1	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.7	PID E2F PATHWAY	E2F transcription factor network
0.0	3.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	6.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4	14.4	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.4	2.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	8.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	12.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.2	3.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	3.4	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	2.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	2.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	5.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	3.5	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	4.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.1	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	1.7	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	3.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	5.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	3.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	0.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	1.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	2.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	1.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.8	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	1.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	3.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	2.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	2.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	1.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.0	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)

Results for LHX6

Z-value: 1.66

Motif logo

Transcription factors associated with LHX6

Activity-expression correlation:

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: