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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for LHX8

Z-value: 0.10

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Transcription factors associated with LHX8

Gene Symbol Gene ID Gene Info
LHX8
ENSG00000162624.15 LHX8

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_28282086 9.82 ENST00000375719.7
ENST00000375732.5
MPP7
membrane palmitoylated protein 7
chr18_-_14132423 7.10 ENST00000589498.5
ENST00000590202.3
ZNF519
zinc finger protein 519
chr6_+_29301701 6.75 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr11_-_5227063 6.66 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr22_+_29480211 6.61 ENST00000310624.7
NEFH
neurofilament heavy
chr18_+_74148508 5.62 ENST00000580087.5
ENST00000169551.11
TIMM21
translocase of inner mitochondrial membrane 21
chr7_-_78489900 5.61 ENST00000636039.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_151261839 5.59 ENST00000331426.6
RBM43
RNA binding motif protein 43
chr19_+_21505585 5.29 ENST00000358491.9
ENST00000597078.5
ZNF429
zinc finger protein 429
chr19_+_21505656 5.28 ENST00000618549.1
ZNF429
zinc finger protein 429
chr17_-_8376658 5.10 ENST00000643221.1
ENST00000647210.1
ENST00000649935.1
ENST00000396267.3
KRBA2
KRAB-A domain containing 2
chr4_+_105710809 4.71 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
GSTCD
glutathione S-transferase C-terminal domain containing
chrX_+_103776493 4.70 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
PLP1
proteolipid protein 1
chr6_+_29396555 4.66 ENST00000623183.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr6_+_43576205 4.31 ENST00000372226.1
ENST00000443535.1
POLH
DNA polymerase eta
chr16_+_22206255 4.29 ENST00000263026.10
EEF2K
eukaryotic elongation factor 2 kinase
chr19_+_12064720 4.03 ENST00000550826.1
ENST00000439326.8
ZNF844
zinc finger protein 844
chr1_-_160523204 3.82 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAMF6
SLAM family member 6
chr8_-_81483226 3.73 ENST00000256104.5
FABP4
fatty acid binding protein 4
chr15_-_65133780 3.60 ENST00000204549.9
PDCD7
programmed cell death 7
chr11_-_114595777 3.56 ENST00000375478.4
NXPE4
neurexophilin and PC-esterase domain family member 4
chr7_-_120858066 3.52 ENST00000222747.8
TSPAN12
tetraspanin 12
chr16_-_20327801 3.47 ENST00000381360.9
GP2
glycoprotein 2
chr7_-_20217342 3.33 ENST00000400331.10
ENST00000332878.8
MACC1
MET transcriptional regulator MACC1
chr7_-_14841267 3.25 ENST00000406247.7
ENST00000399322.7
DGKB
diacylglycerol kinase beta
chrX_+_136205982 3.10 ENST00000628568.1
FHL1
four and a half LIM domains 1
chr4_-_79326008 3.04 ENST00000286794.5
NAA11
N-alpha-acetyltransferase 11, NatA catalytic subunit
chr9_-_21187671 3.04 ENST00000421715.2
IFNA4
interferon alpha 4
chr2_-_151973780 2.81 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr10_-_68471882 2.78 ENST00000551118.6
DNA2
DNA replication helicase/nuclease 2
chr4_-_145180496 2.76 ENST00000447906.8
OTUD4
OTU deubiquitinase 4
chr3_+_98147479 2.71 ENST00000641380.1
OR5H14
olfactory receptor family 5 subfamily H member 14
chr8_-_26045360 2.71 ENST00000520164.6
EBF2
EBF transcription factor 2
chr3_-_57165332 2.64 ENST00000296318.12
IL17RD
interleukin 17 receptor D
chr13_+_73054969 2.62 ENST00000539231.5
KLF5
Kruppel like factor 5
chr2_-_182427014 2.50 ENST00000409365.5
ENST00000351439.9
PDE1A
phosphodiesterase 1A
chr16_-_20327426 2.45 ENST00000575582.5
ENST00000341642.9
ENST00000381362.8
ENST00000572347.5
ENST00000572478.5
ENST00000302555.10
GP2
glycoprotein 2
chr6_-_56642788 2.42 ENST00000439203.5
ENST00000518935.5
ENST00000370765.11
ENST00000244364.10
DST
dystonin
chr6_-_52763473 2.28 ENST00000493422.3
GSTA2
glutathione S-transferase alpha 2
chr9_-_21228222 2.24 ENST00000413767.2
IFNA17
interferon alpha 17
chr2_-_224402097 2.24 ENST00000409685.4
FAM124B
family with sequence similarity 124 member B
chr3_-_149752443 2.22 ENST00000473414.6
COMMD2
COMM domain containing 2
chr12_+_14419136 2.20 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_+_70411241 2.16 ENST00000370938.8
ENST00000346806.2
CTH
cystathionine gamma-lyase
chr10_-_68471911 2.15 ENST00000358410.8
ENST00000399180.3
DNA2
DNA replication helicase/nuclease 2
chr17_-_3398410 2.14 ENST00000322608.2
OR1E1
olfactory receptor family 1 subfamily E member 1
chr4_+_87832917 2.11 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr6_+_29395631 2.10 ENST00000642051.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr1_-_48472166 2.09 ENST00000371847.8
ENST00000396199.7
SPATA6
spermatogenesis associated 6
chrX_+_109536641 2.08 ENST00000372107.5
NXT2
nuclear transport factor 2 like export factor 2
chr19_+_47349298 2.08 ENST00000328771.9
DHX34
DExH-box helicase 34
chr16_-_53703810 2.06 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1L
RPGRIP1 like
chr12_+_101594849 2.05 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
MYBPC1
myosin binding protein C1
chr6_-_49713564 2.03 ENST00000616725.4
ENST00000618917.4
CRISP2
cysteine rich secretory protein 2
chr1_+_119414931 2.02 ENST00000543831.5
ENST00000433745.5
ENST00000369416.4
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr12_-_54588516 2.01 ENST00000547431.5
PPP1R1A
protein phosphatase 1 regulatory inhibitor subunit 1A
chr1_+_212035717 1.97 ENST00000366991.5
DTL
denticleless E3 ubiquitin protein ligase homolog
chr16_-_53703883 1.91 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1L
RPGRIP1 like
chr4_-_67883987 1.90 ENST00000283916.11
TMPRSS11D
transmembrane serine protease 11D
chr5_-_24644968 1.90 ENST00000264463.8
CDH10
cadherin 10
chr4_-_108762964 1.83 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ETNPPL
ethanolamine-phosphate phospho-lyase
chr11_+_59511368 1.83 ENST00000641278.1
OR4D9
olfactory receptor family 4 subfamily D member 9
chr12_-_71157992 1.82 ENST00000247829.8
TSPAN8
tetraspanin 8
chr3_+_148827800 1.81 ENST00000282957.9
ENST00000468341.1
CPB1
carboxypeptidase B1
chr14_+_22543179 1.80 ENST00000390534.1
TRAJ3
T cell receptor alpha joining 3
chr22_+_50738198 1.79 ENST00000216139.10
ENST00000529621.1
ACR
acrosin
chr12_-_71157872 1.77 ENST00000546561.2
TSPAN8
tetraspanin 8
chr11_-_84923403 1.76 ENST00000532653.5
DLG2
discs large MAGUK scaffold protein 2
chr4_-_99321362 1.65 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_-_84923162 1.64 ENST00000524982.5
DLG2
discs large MAGUK scaffold protein 2
chr18_+_45615473 1.64 ENST00000255226.11
SLC14A2
solute carrier family 14 member 2
chrX_-_21758021 1.63 ENST00000646008.1
SMPX
small muscle protein X-linked
chr2_-_39779217 1.62 ENST00000505747.6
THUMPD2
THUMP domain containing 2
chr10_+_84452208 1.60 ENST00000480006.1
CCSER2
coiled-coil serine rich protein 2
chr2_-_49974155 1.59 ENST00000635519.1
NRXN1
neurexin 1
chr3_+_119468952 1.58 ENST00000476573.5
ENST00000295588.9
POGLUT1
protein O-glucosyltransferase 1
chr1_-_236281951 1.56 ENST00000354619.10
ERO1B
endoplasmic reticulum oxidoreductase 1 beta
chrX_-_21758097 1.55 ENST00000379494.4
SMPX
small muscle protein X-linked
chr1_+_108877135 1.54 ENST00000675086.1
ENST00000676184.1
ENST00000675087.1
GPSM2
G protein signaling modulator 2
chr6_+_26087417 1.54 ENST00000357618.10
ENST00000309234.10
HFE
homeostatic iron regulator
chr15_-_34754989 1.51 ENST00000290374.5
GJD2
gap junction protein delta 2
chr12_+_48122574 1.48 ENST00000549022.5
ENST00000547587.5
ENST00000312352.11
PFKM
phosphofructokinase, muscle
chr10_-_29634964 1.47 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr10_-_100065394 1.47 ENST00000441382.1
CPN1
carboxypeptidase N subunit 1
chr8_+_18391276 1.45 ENST00000286479.4
ENST00000520116.1
NAT2
N-acetyltransferase 2
chr18_-_63661884 1.44 ENST00000332821.8
ENST00000283752.10
SERPINB3
serpin family B member 3
chr21_+_38272410 1.42 ENST00000398934.5
ENST00000398930.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr6_+_154039480 1.42 ENST00000229768.9
ENST00000419506.6
ENST00000524163.5
ENST00000414028.6
ENST00000435918.6
ENST00000337049.8
OPRM1
opioid receptor mu 1
chrX_-_31178149 1.41 ENST00000679437.1
DMD
dystrophin
chr15_-_34318761 1.41 ENST00000290209.9
SLC12A6
solute carrier family 12 member 6
chr12_-_54588636 1.41 ENST00000257905.13
PPP1R1A
protein phosphatase 1 regulatory inhibitor subunit 1A
chr19_+_44212525 1.40 ENST00000391961.6
ENST00000621083.4
ENST00000313040.12
ENST00000586228.5
ENST00000588219.5
ENST00000589707.5
ENST00000588394.5
ENST00000589005.5
ZNF227
zinc finger protein 227
chrX_+_85003863 1.40 ENST00000373173.7
APOOL
apolipoprotein O like
chr2_+_86907953 1.39 ENST00000409776.6
RGPD1
RANBP2 like and GRIP domain containing 1
chr7_-_30550761 1.34 ENST00000598361.4
ENST00000440438.6
ENSG00000281039.1
GARS1-DT
novel protein
GARS1 divergent transcript
chr2_-_49974182 1.31 ENST00000412315.5
ENST00000378262.7
NRXN1
neurexin 1
chr5_+_140786136 1.28 ENST00000378133.4
ENST00000504120.4
PCDHA1
protocadherin alpha 1
chr1_+_28369705 1.27 ENST00000373839.8
PHACTR4
phosphatase and actin regulator 4
chr7_-_13986439 1.27 ENST00000443608.5
ENST00000438956.5
ETV1
ETS variant transcription factor 1
chr9_+_26956384 1.23 ENST00000518614.5
ENST00000380062.10
IFT74
intraflagellar transport 74
chr12_+_26195313 1.23 ENST00000422622.3
SSPN
sarcospan
chr6_+_152750789 1.22 ENST00000367244.8
ENST00000367243.7
VIP
vasoactive intestinal peptide
chrX_+_129906118 1.20 ENST00000425117.6
UTP14A
UTP14A small subunit processome component
chr8_-_97277890 1.18 ENST00000322128.5
TSPYL5
TSPY like 5
chr4_+_56436233 1.18 ENST00000512576.3
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr12_-_11269696 1.15 ENST00000381842.7
PRB3
proline rich protein BstNI subfamily 3
chr4_-_94342826 1.14 ENST00000295256.10
HPGDS
hematopoietic prostaglandin D synthase
chr19_-_23687163 1.11 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
ZNF675
zinc finger protein 675
chr6_+_26087281 1.10 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
HFE
homeostatic iron regulator
chr17_+_46923075 1.09 ENST00000640608.1
ENST00000638634.1
ENST00000623037.2
ENST00000225567.9
ENST00000415811.7
ENST00000576910.7
ENST00000573224.2
ENST00000640621.1
ENST00000638892.1
ENST00000638838.1
ENST00000638216.1
ENST00000575949.6
ENST00000640806.1
ENST00000640269.1
ENST00000640443.1
ENST00000638697.1
ENST00000640051.2
ENST00000640007.1
ENST00000640711.1
ENST00000640495.1
ENST00000638374.1
ENST00000571048.1
ENST00000639287.1
ENST00000640138.1
ENST00000570879.2
ENST00000640068.1
ENST00000393456.7
ENST00000639031.1
GOSR2
golgi SNAP receptor complex member 2
chr3_-_109337572 1.08 ENST00000335658.6
DPPA4
developmental pluripotency associated 4
chr9_-_21166660 1.07 ENST00000380225.1
IFNA21
interferon alpha 21
chr4_-_86101922 1.07 ENST00000472236.5
ENST00000641881.1
MAPK10
mitogen-activated protein kinase 10
chr2_+_172860038 1.06 ENST00000538974.5
ENST00000540783.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr9_-_15472732 1.05 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr11_-_59845496 1.05 ENST00000257248.3
CBLIF
cobalamin binding intrinsic factor
chr8_+_74350394 1.05 ENST00000675928.1
ENST00000676443.1
ENST00000676112.1
ENST00000674710.1
ENST00000434412.3
ENST00000675165.1
ENST00000674973.1
ENST00000220822.12
ENST00000675999.1
ENST00000523640.2
ENST00000524195.2
ENST00000675463.1
ENST00000676207.1
ENST00000674865.1
ENST00000676415.1
GDAP1
ganglioside induced differentiation associated protein 1
chr4_+_69995958 1.01 ENST00000381060.2
ENST00000246895.9
STATH
statherin
chr7_+_90245207 0.99 ENST00000497910.5
CFAP69
cilia and flagella associated protein 69
chr9_-_21351378 0.98 ENST00000380210.1
IFNA6
interferon alpha 6
chr4_-_185812209 0.97 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
SORBS2
sorbin and SH3 domain containing 2
chr12_+_48472559 0.97 ENST00000266594.4
ANP32D
acidic nuclear phosphoprotein 32 family member D
chr2_-_111884117 0.95 ENST00000341068.8
ANAPC1
anaphase promoting complex subunit 1
chr19_+_21020634 0.94 ENST00000599548.5
ENST00000594110.5
ENST00000261560.10
ZNF430
zinc finger protein 430
chr10_+_52128343 0.93 ENST00000672084.1
PRKG1
protein kinase cGMP-dependent 1
chr4_-_103719980 0.93 ENST00000304883.3
TACR3
tachykinin receptor 3
chr1_+_99264473 0.92 ENST00000370185.9
PLPPR4
phospholipid phosphatase related 4
chr12_-_11395556 0.90 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
PRB2
PRB1
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr1_-_204190324 0.89 ENST00000638118.1
REN
renin
chr19_+_827823 0.89 ENST00000233997.4
AZU1
azurocidin 1
chr20_-_49915509 0.89 ENST00000289431.10
SPATA2
spermatogenesis associated 2
chr12_-_52452139 0.87 ENST00000252252.4
KRT6B
keratin 6B
chr19_-_48044037 0.84 ENST00000293255.3
CABP5
calcium binding protein 5
chr14_+_102362931 0.81 ENST00000359520.12
TECPR2
tectonin beta-propeller repeat containing 2
chr14_+_56579782 0.80 ENST00000261556.11
ENST00000538838.5
TMEM260
transmembrane protein 260
chr12_-_21334858 0.79 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
SLCO1A2
solute carrier organic anion transporter family member 1A2
chr12_-_10810168 0.78 ENST00000240691.4
TAS2R9
taste 2 receptor member 9
chr16_+_67893244 0.75 ENST00000291041.6
ENST00000570631.5
PSKH1
protein serine kinase H1
chrX_+_12137409 0.74 ENST00000672010.1
FRMPD4
FERM and PDZ domain containing 4
chr12_+_131711072 0.73 ENST00000261674.9
ENST00000541286.5
SFSWAP
splicing factor SWAP
chr2_+_233712905 0.72 ENST00000373414.4
UGT1A5
UDP glucuronosyltransferase family 1 member A5
chr8_+_142834247 0.69 ENST00000522728.5
GML
glycosylphosphatidylinositol anchored molecule like
chr14_-_36521149 0.68 ENST00000518149.5
NKX2-1
NK2 homeobox 1
chr12_+_63779894 0.64 ENST00000261234.11
RXYLT1
ribitol xylosyltransferase 1
chr9_-_21207143 0.63 ENST00000357374.2
IFNA10
interferon alpha 10
chr1_-_217089627 0.63 ENST00000361525.7
ESRRG
estrogen related receptor gamma
chr1_+_197268204 0.61 ENST00000535699.5
ENST00000538660.5
CRB1
crumbs cell polarity complex component 1
chr7_-_13986498 0.61 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETV1
ETS variant transcription factor 1
chr3_+_41194741 0.58 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
CTNNB1
catenin beta 1
chr8_+_17497078 0.55 ENST00000494857.6
ENST00000522656.5
SLC7A2
solute carrier family 7 member 2
chr6_-_63319943 0.55 ENST00000622415.1
ENST00000370658.9
ENST00000485906.6
ENST00000370657.9
LGSN
lengsin, lens protein with glutamine synthetase domain
chr10_+_88664439 0.55 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
LIPF
lipase F, gastric type
chr14_+_39114289 0.53 ENST00000396249.7
ENST00000250379.13
ENST00000534684.7
ENST00000308317.12
ENST00000527381.2
GEMIN2
gem nuclear organelle associated protein 2
chr17_+_29246852 0.50 ENST00000225387.8
CRYBA1
crystallin beta A1
chr4_+_70242583 0.50 ENST00000304954.3
CSN3
casein kappa
chr3_-_46812558 0.50 ENST00000641183.1
ENST00000460241.2
ENSG00000284672.1
ENSG00000206549.13
novel transcript
novel protein identical to PRSS50
chr19_-_39738017 0.49 ENST00000221804.5
CLC
Charcot-Leyden crystal galectin
chr5_+_141213919 0.48 ENST00000341948.6
PCDHB13
protocadherin beta 13
chr17_+_59940908 0.48 ENST00000591035.1
ENSG00000267318.1
novel protein
chr5_-_147782681 0.48 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
JAKMIP2
janus kinase and microtubule interacting protein 2
chr15_-_43493105 0.47 ENST00000382039.7
ENST00000450115.6
ENST00000382044.9
TP53BP1
tumor protein p53 binding protein 1
chr2_-_31414694 0.46 ENST00000379416.4
XDH
xanthine dehydrogenase
chr8_+_17497108 0.45 ENST00000470360.5
SLC7A2
solute carrier family 7 member 2
chr6_-_55875583 0.44 ENST00000370830.4
BMP5
bone morphogenetic protein 5
chr14_+_71933116 0.41 ENST00000553530.5
ENST00000556437.5
RGS6
regulator of G protein signaling 6
chr6_+_26251607 0.39 ENST00000619466.2
H2BC9
H2B clustered histone 9
chrX_+_109535775 0.37 ENST00000218004.5
NXT2
nuclear transport factor 2 like export factor 2
chr8_+_86342539 0.37 ENST00000517970.6
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr9_-_179008 0.36 ENST00000613508.4
ENST00000382447.8
ENST00000382389.5
ENST00000377447.7
ENST00000382393.2
ENST00000314367.14
ENST00000356521.8
ENST00000377400.8
CBWD1
COBW domain containing 1
chr9_-_13165442 0.36 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr10_+_92593112 0.35 ENST00000260731.5
KIF11
kinesin family member 11
chr1_+_182450132 0.33 ENST00000294854.13
RGSL1
regulator of G protein signaling like 1
chr13_-_46897021 0.32 ENST00000542664.4
ENST00000543956.5
HTR2A
5-hydroxytryptamine receptor 2A
chr7_+_64045420 0.30 ENST00000647787.1
ENST00000456806.3
ENSG00000285544.1
ZNF727
novel transcript
zinc finger protein 727
chr9_+_65675834 0.27 ENST00000377392.9
ENST00000377384.5
ENST00000430059.6
ENST00000429800.6
ENST00000382405.8
ENST00000377395.8
CBWD5
COBW domain containing 5
chr10_+_133394094 0.24 ENST00000477902.6
MTG1
mitochondrial ribosome associated GTPase 1
chr15_+_65550819 0.22 ENST00000569894.5
HACD3
3-hydroxyacyl-CoA dehydratase 3
chr2_+_216499068 0.22 ENST00000456586.5
ENST00000427280.6
ENST00000598925.5
ENST00000441179.2
RPL37A
ribosomal protein L37a
chr1_-_147670513 0.22 ENST00000583509.7
ACP6
acid phosphatase 6, lysophosphatidic
chr9_+_68241854 0.21 ENST00000616550.4
ENST00000618217.4
ENST00000377342.9
ENST00000478048.5
ENST00000360171.11
CBWD3
COBW domain containing 3
chr7_-_32070396 0.21 ENST00000396191.6
PDE1C
phosphodiesterase 1C
chr3_-_119463606 0.18 ENST00000319172.10
ENST00000491685.5
ENST00000461654.1
TMEM39A
transmembrane protein 39A
chr7_-_22194709 0.17 ENST00000458533.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr2_+_233917371 0.17 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chrX_+_56232411 0.17 ENST00000374928.7
KLF8
Kruppel like factor 8
chr10_+_94683771 0.16 ENST00000339022.6
CYP2C18
cytochrome P450 family 2 subfamily C member 18
chr4_+_73409340 0.15 ENST00000511370.1
ALB
albumin
chr12_+_93677556 0.08 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr9_-_41189310 0.05 ENST00000456520.5
ENST00000377391.8
ENST00000613716.4
ENST00000617933.1
CBWD6
COBW domain containing 6
chr1_-_113871665 0.04 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
PTPN22
protein tyrosine phosphatase non-receptor type 22
chr6_-_24489565 0.04 ENST00000230036.2
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr13_+_38349822 0.03 ENST00000379649.5
ENST00000239878.9
UFM1
ubiquitin fold modifier 1
chr6_+_29170907 0.03 ENST00000641417.1
OR2J2
olfactory receptor family 2 subfamily J member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0030185 nitric oxide transport(GO:0030185)
1.8 7.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.7 6.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.6 4.9 GO:0043504 mitochondrial DNA repair(GO:0043504)
1.6 9.8 GO:0071896 protein localization to adherens junction(GO:0071896)
1.1 4.3 GO:1990637 response to prolactin(GO:1990637)
1.0 3.0 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.9 2.6 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.9 4.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.6 3.0 GO:0030070 insulin processing(GO:0030070)
0.6 5.6 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.5 1.4 GO:0035425 autocrine signaling(GO:0035425)
0.4 2.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.4 5.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.4 1.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 1.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.4 1.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.4 8.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.4 5.1 GO:0015074 DNA integration(GO:0015074)
0.4 1.4 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.3 1.0 GO:1903826 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) arginine transmembrane transport(GO:1903826)
0.3 2.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 1.5 GO:0031291 Ran protein signal transduction(GO:0031291)
0.3 1.8 GO:0007341 penetration of zona pellucida(GO:0007341)
0.3 1.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.3 0.9 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.3 1.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 4.0 GO:0021670 lateral ventricle development(GO:0021670)
0.3 2.9 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 3.8 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.2 4.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 2.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 3.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 1.4 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 20.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 2.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 1.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.5 GO:0046110 purine nucleobase catabolic process(GO:0006145) xanthine metabolic process(GO:0046110)
0.1 0.7 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.4 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 2.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.7 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.2 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.9 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 1.0 GO:0046541 saliva secretion(GO:0046541)
0.1 1.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 2.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 3.5 GO:0010842 retina layer formation(GO:0010842)
0.1 0.6 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 2.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.8 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 3.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.3 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 6.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 2.1 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 2.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 2.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.6 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.5 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 2.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 2.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 2.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 3.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 3.1 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.9 GO:0007398 ectoderm development(GO:0007398)
0.0 3.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 1.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 1.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 2.8 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.6 4.9 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.7 2.1 GO:0097224 sperm connecting piece(GO:0097224)
0.7 4.0 GO:0005879 axonemal microtubule(GO:0005879)
0.6 1.8 GO:0043159 acrosomal matrix(GO:0043159)
0.5 3.2 GO:0005927 muscle tendon junction(GO:0005927)
0.5 2.4 GO:0031673 H zone(GO:0031673)
0.4 6.6 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 2.6 GO:1990357 terminal web(GO:1990357)
0.4 3.0 GO:0031415 NatA complex(GO:0031415)
0.4 5.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.4 5.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 8.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 2.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 1.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.5 GO:0036449 microtubule minus-end(GO:0036449)
0.2 3.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.4 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 2.0 GO:0032982 myosin filament(GO:0032982)
0.1 3.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.3 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 6.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 4.9 GO:0043209 myelin sheath(GO:0043209)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0031862 prostanoid receptor binding(GO:0031862)
1.0 3.0 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
1.0 4.9 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.9 9.5 GO:0005549 odorant binding(GO:0005549)
0.7 5.2 GO:0030492 hemoglobin binding(GO:0030492)
0.7 5.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 1.8 GO:0042806 amidase activity(GO:0004040) fucose binding(GO:0042806)
0.5 8.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.5 1.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.5 2.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 2.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 1.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 3.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 2.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 1.6 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.4 4.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 1.4 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.3 1.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.3 1.0 GO:0015181 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181)
0.3 1.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 2.6 GO:0039706 co-receptor binding(GO:0039706)
0.2 2.1 GO:0032027 myosin light chain binding(GO:0032027)
0.2 1.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 3.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 0.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 1.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 2.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 3.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 4.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 5.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 2.0 GO:0031432 titin binding(GO:0031432)
0.1 1.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 10.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 3.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 2.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 1.8 GO:0008483 transaminase activity(GO:0008483)
0.1 3.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 8.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 2.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 2.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 2.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 8.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 4.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 8.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 1.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 5.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 10.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.5 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 2.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 7.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 2.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 9.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides