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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for MAFB
Z-value: 8.28
Motif logo
Transcription factors associated with MAFB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MAFB
|
ENSG00000204103.4 | MAFB |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MAFB | hg38_v1_chr20_-_40689228_40689244 | 0.12 | 9.0e-02 | Click! |
Activity profile of MAFB motif
Sorted Z-values of MAFB motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MAFB
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.6 | 26.6 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 6.0 | 29.9 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 5.4 | 21.6 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 5.2 | 15.7 | GO:0036146 | cellular response to mycotoxin(GO:0036146) |
| 5.2 | 15.6 | GO:0061027 | umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027) |
| 5.1 | 25.5 | GO:0021586 | pons maturation(GO:0021586) |
| 4.6 | 23.2 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 4.5 | 27.2 | GO:0071874 | cellular response to norepinephrine stimulus(GO:0071874) |
| 4.4 | 13.2 | GO:1904692 | positive regulation of type B pancreatic cell proliferation(GO:1904692) |
| 4.4 | 26.1 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 4.3 | 12.9 | GO:0099526 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 3.7 | 11.0 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 3.7 | 14.7 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 3.6 | 14.4 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 3.5 | 10.6 | GO:0006683 | galactosylceramide catabolic process(GO:0006683) |
| 3.4 | 13.4 | GO:2000077 | negative regulation of type B pancreatic cell development(GO:2000077) |
| 3.2 | 38.6 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 3.0 | 8.9 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 2.9 | 8.8 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 2.9 | 11.6 | GO:1990535 | neuron projection maintenance(GO:1990535) |
| 2.9 | 8.7 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 2.8 | 14.2 | GO:0030070 | insulin processing(GO:0030070) |
| 2.8 | 5.6 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 2.8 | 13.9 | GO:1902612 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 2.8 | 8.3 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
| 2.7 | 21.9 | GO:0046061 | dATP catabolic process(GO:0046061) |
| 2.7 | 10.8 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 2.7 | 13.3 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 2.6 | 13.1 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 2.6 | 15.4 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 2.5 | 2.5 | GO:0051946 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 2.4 | 7.2 | GO:1902771 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 2.4 | 56.8 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 2.4 | 11.8 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 2.3 | 2.3 | GO:0046514 | ceramide catabolic process(GO:0046514) |
| 2.2 | 6.7 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 2.2 | 8.9 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 2.2 | 6.7 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 2.2 | 6.7 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 2.2 | 6.6 | GO:2000538 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 2.2 | 8.8 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 2.2 | 19.5 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 2.1 | 2.1 | GO:0032230 | positive regulation of synaptic transmission, GABAergic(GO:0032230) |
| 2.1 | 8.4 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 2.1 | 6.3 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 2.1 | 39.8 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 2.1 | 12.3 | GO:0003190 | atrioventricular valve formation(GO:0003190) |
| 2.0 | 42.7 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 2.0 | 8.1 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 2.0 | 12.1 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 2.0 | 2.0 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 2.0 | 9.8 | GO:2001074 | regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
| 1.9 | 3.9 | GO:2001280 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 1.9 | 17.3 | GO:0016322 | neuron remodeling(GO:0016322) |
| 1.9 | 9.6 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 1.9 | 30.5 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 1.9 | 13.3 | GO:0015959 | diadenosine polyphosphate metabolic process(GO:0015959) |
| 1.9 | 5.6 | GO:0046066 | dGDP metabolic process(GO:0046066) |
| 1.9 | 5.6 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 1.8 | 7.3 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 1.8 | 5.4 | GO:1903281 | protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 1.8 | 30.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 1.8 | 19.5 | GO:0070444 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 1.7 | 6.9 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 1.7 | 6.9 | GO:1900736 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 1.7 | 3.4 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) |
| 1.7 | 6.7 | GO:0021759 | globus pallidus development(GO:0021759) |
| 1.7 | 6.7 | GO:0009305 | protein biotinylation(GO:0009305) histone biotinylation(GO:0071110) |
| 1.7 | 1.7 | GO:0036115 | fatty-acyl-CoA catabolic process(GO:0036115) |
| 1.7 | 6.7 | GO:0071673 | positive regulation of smooth muscle cell chemotaxis(GO:0071673) |
| 1.7 | 13.3 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 1.7 | 1.7 | GO:0014901 | regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) |
| 1.6 | 3.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 1.6 | 4.7 | GO:0060005 | vestibular reflex(GO:0060005) |
| 1.6 | 7.8 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 1.6 | 1.6 | GO:0032416 | negative regulation of sodium:proton antiporter activity(GO:0032416) |
| 1.5 | 17.0 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 1.5 | 20.1 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 1.5 | 7.7 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 1.5 | 18.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 1.5 | 4.6 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 1.5 | 7.6 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 1.5 | 4.5 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 1.5 | 3.0 | GO:0060734 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) |
| 1.5 | 16.6 | GO:0097186 | amelogenesis(GO:0097186) |
| 1.5 | 4.5 | GO:2000583 | regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 1.5 | 4.5 | GO:1902809 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 1.5 | 4.5 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 1.5 | 4.4 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
| 1.4 | 27.2 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 1.4 | 10.0 | GO:0033029 | regulation of neutrophil apoptotic process(GO:0033029) |
| 1.4 | 9.9 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 1.4 | 4.2 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 1.4 | 6.9 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 1.4 | 5.5 | GO:0048294 | negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 1.3 | 14.8 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 1.3 | 9.3 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 1.3 | 11.8 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 1.3 | 7.9 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 1.3 | 3.9 | GO:0048808 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
| 1.3 | 18.3 | GO:2001015 | negative regulation of skeletal muscle cell differentiation(GO:2001015) |
| 1.3 | 9.1 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 1.3 | 1.3 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
| 1.3 | 3.8 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 1.3 | 5.1 | GO:0097676 | histone H3-K36 dimethylation(GO:0097676) |
| 1.3 | 6.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.3 | 8.8 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) |
| 1.3 | 12.5 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 1.3 | 11.3 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 1.2 | 2.5 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 1.2 | 8.7 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 1.2 | 2.5 | GO:2000566 | positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) |
| 1.2 | 7.4 | GO:1902075 | cellular response to salt(GO:1902075) |
| 1.2 | 34.7 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 1.2 | 3.6 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021) |
| 1.2 | 19.0 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 1.2 | 2.4 | GO:0007354 | zygotic determination of anterior/posterior axis, embryo(GO:0007354) |
| 1.2 | 15.4 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 1.2 | 11.8 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 1.2 | 4.7 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 1.2 | 5.8 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 1.2 | 9.3 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
| 1.2 | 2.3 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 1.1 | 4.6 | GO:1900827 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 1.1 | 17.2 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 1.1 | 4.6 | GO:2000297 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) negative regulation of synapse maturation(GO:2000297) |
| 1.1 | 6.8 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 1.1 | 10.1 | GO:0046549 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 1.1 | 1.1 | GO:0046533 | negative regulation of photoreceptor cell differentiation(GO:0046533) |
| 1.1 | 18.9 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 1.1 | 3.3 | GO:1903421 | regulation of synaptic vesicle recycling(GO:1903421) |
| 1.1 | 5.4 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 1.1 | 31.1 | GO:0032011 | ARF protein signal transduction(GO:0032011) |
| 1.1 | 3.2 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
| 1.1 | 6.3 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.0 | 15.7 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 1.0 | 6.3 | GO:0007135 | meiosis II(GO:0007135) |
| 1.0 | 4.2 | GO:0045658 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 1.0 | 3.1 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 1.0 | 8.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 1.0 | 15.4 | GO:0035878 | nail development(GO:0035878) |
| 1.0 | 3.1 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 1.0 | 8.2 | GO:0050942 | positive regulation of pigment cell differentiation(GO:0050942) |
| 1.0 | 2.0 | GO:0061582 | intestinal epithelial cell migration(GO:0061582) |
| 1.0 | 19.0 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 1.0 | 4.0 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
| 1.0 | 9.0 | GO:0042182 | ketone catabolic process(GO:0042182) |
| 1.0 | 6.0 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 1.0 | 6.0 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 1.0 | 12.8 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 1.0 | 8.8 | GO:1901678 | iron coordination entity transport(GO:1901678) |
| 1.0 | 3.9 | GO:0033590 | response to cobalamin(GO:0033590) |
| 1.0 | 3.9 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 1.0 | 1.0 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 1.0 | 1.9 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 1.0 | 1.9 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.9 | 2.8 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.9 | 10.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.9 | 9.4 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.9 | 11.0 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.9 | 3.7 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.9 | 0.9 | GO:1902913 | positive regulation of neuroepithelial cell differentiation(GO:1902913) |
| 0.9 | 6.4 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.9 | 4.5 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767) |
| 0.9 | 2.7 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.9 | 0.9 | GO:0032632 | interleukin-3 production(GO:0032632) |
| 0.9 | 3.5 | GO:0048690 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.9 | 27.1 | GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.9 | 2.6 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 0.9 | 5.2 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 0.9 | 5.2 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.9 | 12.8 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.8 | 1.7 | GO:0060023 | soft palate development(GO:0060023) |
| 0.8 | 2.5 | GO:0070845 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.8 | 26.6 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.8 | 14.1 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.8 | 2.5 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 0.8 | 1.7 | GO:0060687 | regulation of branching involved in prostate gland morphogenesis(GO:0060687) |
| 0.8 | 10.6 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.8 | 2.4 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 0.8 | 14.5 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.8 | 3.2 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.8 | 3.2 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 0.8 | 4.7 | GO:0000436 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) |
| 0.8 | 29.2 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.8 | 7.1 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 0.8 | 2.4 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.8 | 27.4 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.8 | 2.3 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 0.8 | 3.1 | GO:0045626 | negative regulation of T-helper 1 cell differentiation(GO:0045626) |
| 0.8 | 4.6 | GO:0010734 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.8 | 5.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.8 | 3.1 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) |
| 0.8 | 2.3 | GO:2001183 | negative regulation of interleukin-12 secretion(GO:2001183) |
| 0.8 | 1.5 | GO:0070346 | positive regulation of fat cell proliferation(GO:0070346) |
| 0.8 | 3.0 | GO:0032489 | regulation of Cdc42 protein signal transduction(GO:0032489) |
| 0.8 | 12.0 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.8 | 7.5 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.7 | 3.7 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.7 | 0.7 | GO:0060128 | corticotropin hormone secreting cell differentiation(GO:0060128) |
| 0.7 | 6.7 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.7 | 3.0 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 0.7 | 5.2 | GO:0002645 | positive regulation of tolerance induction(GO:0002645) |
| 0.7 | 4.5 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.7 | 6.6 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.7 | 5.9 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.7 | 2.9 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.7 | 2.2 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.7 | 1.4 | GO:0021779 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.7 | 5.1 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.7 | 2.2 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.7 | 11.3 | GO:0060973 | cell migration involved in heart development(GO:0060973) |
| 0.7 | 3.5 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.7 | 13.3 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.7 | 1.4 | GO:0032847 | regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849) |
| 0.7 | 14.5 | GO:0046337 | phosphatidylethanolamine metabolic process(GO:0046337) |
| 0.7 | 1.4 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.7 | 15.2 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.7 | 4.1 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.7 | 4.1 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.7 | 6.1 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.7 | 1.3 | GO:0042321 | negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 0.7 | 22.5 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.7 | 4.0 | GO:0015853 | adenine transport(GO:0015853) |
| 0.7 | 4.6 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.7 | 5.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.7 | 3.3 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 0.6 | 2.6 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
| 0.6 | 5.1 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.6 | 3.8 | GO:0042713 | sperm ejaculation(GO:0042713) |
| 0.6 | 1.3 | GO:0003257 | positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 0.6 | 2.6 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.6 | 6.4 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.6 | 3.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.6 | 7.0 | GO:0060992 | response to fungicide(GO:0060992) |
| 0.6 | 6.3 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.6 | 2.5 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.6 | 8.1 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 0.6 | 7.4 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.6 | 8.0 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.6 | 3.7 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.6 | 42.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.6 | 6.1 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.6 | 12.1 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.6 | 5.9 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.6 | 0.6 | GO:1902548 | negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548) |
| 0.6 | 7.0 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.6 | 7.4 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.6 | 2.3 | GO:0051968 | positive regulation of synaptic transmission, glutamatergic(GO:0051968) |
| 0.6 | 6.3 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.6 | 1.7 | GO:1990764 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.6 | 3.4 | GO:0035672 | oligopeptide transmembrane transport(GO:0035672) |
| 0.6 | 1.1 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 0.6 | 1.7 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.6 | 11.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.5 | 3.8 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.5 | 4.9 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.5 | 5.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.5 | 5.4 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.5 | 1.6 | GO:0051710 | regulation of cytolysis in other organism(GO:0051710) |
| 0.5 | 4.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.5 | 1.6 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.5 | 3.7 | GO:0045759 | negative regulation of action potential(GO:0045759) |
| 0.5 | 2.1 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.5 | 6.8 | GO:0021514 | ventral spinal cord interneuron differentiation(GO:0021514) |
| 0.5 | 4.2 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) |
| 0.5 | 2.6 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.5 | 23.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.5 | 7.1 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
| 0.5 | 2.0 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.5 | 1.5 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.5 | 1.5 | GO:0098935 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.5 | 5.5 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.5 | 2.5 | GO:0021853 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.5 | 8.4 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.5 | 2.5 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.5 | 17.2 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.5 | 2.9 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 0.5 | 0.5 | GO:0035625 | epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.5 | 2.4 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.5 | 4.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.5 | 2.8 | GO:0060013 | righting reflex(GO:0060013) |
| 0.5 | 14.2 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.5 | 6.6 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 0.5 | 4.2 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.5 | 5.1 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.5 | 2.8 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.5 | 3.7 | GO:0034086 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
| 0.5 | 3.7 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.5 | 3.2 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.5 | 5.1 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.5 | 0.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.5 | 2.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.4 | 7.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.4 | 0.9 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 0.4 | 7.0 | GO:0021978 | telencephalon regionalization(GO:0021978) |
| 0.4 | 3.0 | GO:1990592 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.4 | 4.8 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.4 | 2.2 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.4 | 0.9 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.4 | 13.8 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.4 | 1.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.4 | 3.0 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.4 | 4.7 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.4 | 3.0 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.4 | 3.8 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.4 | 1.7 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.4 | 0.8 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.4 | 2.9 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.4 | 6.2 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 0.4 | 2.0 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164) |
| 0.4 | 0.8 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 0.4 | 3.2 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.4 | 1.2 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.4 | 4.7 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.4 | 5.5 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.4 | 3.1 | GO:0046958 | nonassociative learning(GO:0046958) habituation(GO:0046959) |
| 0.4 | 0.8 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 0.4 | 5.4 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.4 | 3.1 | GO:0061709 | reticulophagy(GO:0061709) |
| 0.4 | 1.1 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.4 | 5.2 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.4 | 5.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.4 | 3.3 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.4 | 0.4 | GO:2000777 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777) |
| 0.4 | 2.2 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 0.4 | 2.6 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.4 | 3.9 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545) |
| 0.4 | 24.8 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.3 | 2.4 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.3 | 0.3 | GO:0019249 | lactate biosynthetic process(GO:0019249) |
| 0.3 | 3.4 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.3 | 3.8 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.3 | 3.4 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.3 | 3.7 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.3 | 2.4 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.3 | 1.0 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.3 | 1.0 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.3 | 3.3 | GO:0044803 | multi-organism membrane organization(GO:0044803) |
| 0.3 | 2.3 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.3 | 2.3 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.3 | 4.8 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.3 | 1.0 | GO:0036216 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.3 | 2.5 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.3 | 2.2 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 0.3 | 1.6 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 0.3 | 0.9 | GO:0003011 | involuntary skeletal muscle contraction(GO:0003011) |
| 0.3 | 3.1 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.3 | 0.9 | GO:0052422 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 0.3 | 0.6 | GO:0021914 | smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.3 | 4.1 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.3 | 4.1 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.3 | 2.2 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.3 | 4.3 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 0.3 | 2.8 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.3 | 2.5 | GO:0015747 | urate transport(GO:0015747) |
| 0.3 | 3.7 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.3 | 2.5 | GO:0042756 | drinking behavior(GO:0042756) |
| 0.3 | 0.9 | GO:0045062 | extrathymic T cell selection(GO:0045062) |
| 0.3 | 1.5 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.3 | 2.4 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.3 | 5.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.3 | 2.7 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.3 | 2.1 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.3 | 11.4 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.3 | 0.3 | GO:1900109 | regulation of histone H3-K9 dimethylation(GO:1900109) |
| 0.3 | 3.5 | GO:0097237 | cellular response to toxic substance(GO:0097237) |
| 0.3 | 0.6 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.3 | 0.6 | GO:2000317 | negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.3 | 2.8 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.3 | 1.7 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.3 | 6.2 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.3 | 4.2 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.3 | 1.4 | GO:0070255 | regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257) |
| 0.3 | 2.8 | GO:0051775 | response to redox state(GO:0051775) |
| 0.3 | 0.8 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 0.3 | 3.0 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 0.3 | 7.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.3 | 3.8 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.3 | 1.3 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.3 | 2.9 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.3 | 1.6 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.3 | 2.1 | GO:0072201 | negative regulation of mesenchymal cell proliferation(GO:0072201) |
| 0.3 | 4.5 | GO:0007616 | long-term memory(GO:0007616) |
| 0.3 | 36.6 | GO:0050954 | sensory perception of mechanical stimulus(GO:0050954) |
| 0.3 | 1.1 | GO:0015870 | acetylcholine transport(GO:0015870) |
| 0.3 | 20.4 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.3 | 1.8 | GO:0070942 | neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) |
| 0.3 | 0.8 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.3 | 1.6 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.3 | 0.8 | GO:0060068 | vagina development(GO:0060068) |
| 0.3 | 4.9 | GO:0010962 | regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962) |
| 0.3 | 5.7 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.3 | 2.8 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
| 0.3 | 1.5 | GO:0071104 | response to interleukin-9(GO:0071104) |
| 0.3 | 1.0 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.3 | 4.8 | GO:0006833 | water transport(GO:0006833) |
| 0.3 | 1.3 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.3 | 6.0 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 3.9 | GO:0031034 | myosin filament assembly(GO:0031034) |
| 0.2 | 2.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.2 | 0.7 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.2 | 2.4 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.2 | 6.8 | GO:0021904 | dorsal/ventral neural tube patterning(GO:0021904) |
| 0.2 | 1.0 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.2 | 2.4 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.2 | 1.0 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.2 | 1.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.2 | 1.4 | GO:0090500 | endocardial cushion to mesenchymal transition(GO:0090500) |
| 0.2 | 14.5 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.2 | 3.8 | GO:2000758 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 0.2 | 1.6 | GO:0032594 | protein transport within lipid bilayer(GO:0032594) |
| 0.2 | 3.2 | GO:1904152 | regulation of retrograde protein transport, ER to cytosol(GO:1904152) |
| 0.2 | 0.2 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 0.2 | 2.5 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.2 | 16.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.2 | 0.7 | GO:1904693 | midbrain morphogenesis(GO:1904693) |
| 0.2 | 1.6 | GO:0007602 | phototransduction(GO:0007602) |
| 0.2 | 11.4 | GO:0043266 | regulation of potassium ion transport(GO:0043266) |
| 0.2 | 0.2 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.2 | 1.8 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.2 | 2.4 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.2 | 4.2 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.2 | 6.4 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.2 | 2.6 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.2 | 4.3 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.2 | 5.6 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.2 | 5.6 | GO:0000732 | strand displacement(GO:0000732) |
| 0.2 | 1.5 | GO:0050655 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) dermatan sulfate proteoglycan metabolic process(GO:0050655) |
| 0.2 | 1.5 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.2 | 4.7 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
| 0.2 | 2.7 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.2 | 12.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.2 | 13.4 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.2 | 7.8 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
| 0.2 | 7.3 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.2 | 0.6 | GO:1901053 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
| 0.2 | 1.4 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.2 | 20.2 | GO:0048515 | spermatid differentiation(GO:0048515) |
| 0.2 | 3.6 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.2 | 0.8 | GO:0060353 | regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.2 | 2.2 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.2 | 0.4 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
| 0.2 | 1.4 | GO:1901626 | regulation of postsynaptic membrane organization(GO:1901626) |
| 0.2 | 2.0 | GO:0048535 | lymph node development(GO:0048535) |
| 0.2 | 1.2 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 3.3 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.2 | 1.7 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.2 | 3.3 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.2 | 4.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 0.6 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
| 0.2 | 0.6 | GO:0033504 | floor plate development(GO:0033504) |
| 0.2 | 4.6 | GO:0050912 | detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 0.2 | 2.7 | GO:0048820 | hair follicle maturation(GO:0048820) |
| 0.2 | 5.7 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.2 | 2.3 | GO:0043949 | regulation of cAMP-mediated signaling(GO:0043949) |
| 0.2 | 0.3 | GO:0072402 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.2 | 2.1 | GO:0010922 | positive regulation of phosphatase activity(GO:0010922) |
| 0.2 | 1.0 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.2 | 2.2 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.2 | 1.0 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.2 | 1.2 | GO:0097503 | sialylation(GO:0097503) |
| 0.2 | 0.8 | GO:0045342 | MHC class II biosynthetic process(GO:0045342) |
| 0.2 | 0.6 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.2 | 2.4 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.2 | 1.1 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 0.2 | 1.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.2 | 2.5 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.2 | 0.9 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.2 | 3.9 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.2 | 2.7 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 3.0 | GO:0003338 | metanephros morphogenesis(GO:0003338) |
| 0.1 | 2.8 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.7 | GO:1902904 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.1 | 0.7 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.1 | 1.3 | GO:0045794 | negative regulation of cell volume(GO:0045794) |
| 0.1 | 8.7 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.1 | 5.6 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.1 | 4.4 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.1 | 0.4 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.1 | 0.7 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 1.6 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 0.1 | 4.4 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.1 | 3.9 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.1 | 0.3 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.1 | 0.9 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.1 | 2.1 | GO:0033198 | response to ATP(GO:0033198) |
| 0.1 | 0.1 | GO:0033091 | positive regulation of immature T cell proliferation(GO:0033091) |
| 0.1 | 1.6 | GO:1901881 | positive regulation of protein depolymerization(GO:1901881) |
| 0.1 | 1.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 0.4 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.1 | 3.8 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.1 | 2.2 | GO:0031063 | regulation of histone deacetylation(GO:0031063) |
| 0.1 | 0.4 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 8.9 | GO:0061337 | cardiac conduction(GO:0061337) |
| 0.1 | 4.1 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 6.5 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.1 | 1.6 | GO:0061436 | regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436) |
| 0.1 | 1.9 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.1 | 6.9 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.1 | 0.2 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
| 0.1 | 3.0 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.1 | 0.5 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.1 | 4.2 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.1 | 8.0 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.1 | 2.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.1 | 1.0 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 2.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.1 | 2.7 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.1 | 1.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.6 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.1 | 0.5 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 0.8 | GO:1902686 | positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686) |
| 0.1 | 1.5 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.1 | 1.8 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.1 | 2.0 | GO:0034205 | beta-amyloid formation(GO:0034205) |
| 0.1 | 1.2 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.1 | 0.3 | GO:0045623 | negative regulation of T-helper cell differentiation(GO:0045623) |
| 0.1 | 0.4 | GO:0060042 | retina morphogenesis in camera-type eye(GO:0060042) |
| 0.1 | 3.7 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.1 | 1.1 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.4 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.1 | 1.8 | GO:0014044 | Schwann cell development(GO:0014044) |
| 0.1 | 0.3 | GO:0044557 | relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087) |
| 0.1 | 0.7 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.1 | 2.9 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.1 | 0.3 | GO:0030222 | eosinophil differentiation(GO:0030222) |
| 0.1 | 0.8 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 0.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.2 | GO:0034392 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.1 | 0.7 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.1 | 0.8 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.1 | 0.5 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.1 | 0.6 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.1 | 0.3 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 1.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.1 | 0.5 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.1 | 0.9 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 0.8 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.1 | 1.2 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 3.2 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.6 | GO:1900274 | positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274) |
| 0.1 | 7.2 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.1 | 1.7 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.1 | 0.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.1 | 1.1 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 0.8 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 1.4 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.1 | 8.7 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.1 | 41.0 | GO:0007186 | G-protein coupled receptor signaling pathway(GO:0007186) |
| 0.1 | 0.6 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.1 | 3.3 | GO:0050728 | negative regulation of inflammatory response(GO:0050728) |
| 0.1 | 1.1 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 0.5 | GO:0003413 | chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) |
| 0.1 | 0.2 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.1 | 0.5 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.1 | 2.7 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.1 | 1.6 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
| 0.1 | 1.1 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 0.1 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
| 0.1 | 0.1 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.1 | 1.3 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 3.3 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 1.0 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 0.6 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 0.9 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.0 | 0.2 | GO:0031126 | snoRNA 3'-end processing(GO:0031126) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.0 | 0.9 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.0 | 1.0 | GO:0008361 | regulation of cell size(GO:0008361) |
| 0.0 | 1.1 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.3 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.0 | 0.8 | GO:0042953 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.6 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.0 | 3.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.1 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.3 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.1 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.0 | 0.7 | GO:2001057 | reactive nitrogen species metabolic process(GO:2001057) |
| 0.0 | 1.5 | GO:0006813 | potassium ion transport(GO:0006813) |
| 0.0 | 1.8 | GO:0006836 | neurotransmitter transport(GO:0006836) |
| 0.0 | 0.2 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.0 | GO:0002268 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
| 0.0 | 0.5 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.0 | GO:0048485 | sympathetic nervous system development(GO:0048485) |
| 0.0 | 0.2 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.0 | 0.0 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.0 | 0.0 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.0 | 0.3 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.8 | 35.3 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 5.4 | 5.4 | GO:0019034 | viral replication complex(GO:0019034) |
| 4.5 | 17.9 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 4.3 | 12.9 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 3.9 | 23.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 3.7 | 29.9 | GO:0045179 | apical cortex(GO:0045179) |
| 3.2 | 15.9 | GO:0072534 | perineuronal net(GO:0072534) |
| 3.0 | 15.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 2.8 | 16.7 | GO:0045298 | tubulin complex(GO:0045298) |
| 2.7 | 8.2 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 2.3 | 11.4 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 2.1 | 14.6 | GO:0032280 | symmetric synapse(GO:0032280) |
| 2.0 | 31.5 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.9 | 11.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 1.6 | 4.7 | GO:0031251 | PAN complex(GO:0031251) |
| 1.5 | 19.7 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 1.5 | 15.1 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 1.5 | 105.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 1.5 | 8.9 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 1.5 | 10.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 1.5 | 20.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 1.4 | 15.9 | GO:0005955 | calcineurin complex(GO:0005955) |
| 1.4 | 1.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 1.4 | 11.2 | GO:0043203 | axon hillock(GO:0043203) |
| 1.4 | 1.4 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 1.4 | 5.4 | GO:0035363 | histone locus body(GO:0035363) |
| 1.3 | 5.4 | GO:0071546 | pi-body(GO:0071546) |
| 1.3 | 10.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 1.3 | 51.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 1.3 | 6.3 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 1.3 | 5.0 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) |
| 1.2 | 3.7 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 1.2 | 3.7 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 1.2 | 7.4 | GO:0044327 | dendritic spine head(GO:0044327) |
| 1.2 | 62.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 1.2 | 3.6 | GO:0032116 | SMC loading complex(GO:0032116) |
| 1.2 | 10.7 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 1.2 | 14.0 | GO:0016013 | syntrophin complex(GO:0016013) |
| 1.1 | 7.9 | GO:1990745 | EARP complex(GO:1990745) |
| 1.1 | 3.3 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 1.1 | 23.3 | GO:0043194 | axon initial segment(GO:0043194) |
| 1.1 | 13.7 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.0 | 25.9 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 1.0 | 10.3 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 1.0 | 6.1 | GO:0033179 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 1.0 | 9.9 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 1.0 | 11.5 | GO:0016342 | catenin complex(GO:0016342) |
| 1.0 | 4.8 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 1.0 | 4.8 | GO:0001652 | granular component(GO:0001652) |
| 0.9 | 2.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.9 | 13.6 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.9 | 2.7 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.9 | 4.5 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.9 | 9.6 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.8 | 8.4 | GO:0045495 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.8 | 10.9 | GO:0097433 | dense body(GO:0097433) |
| 0.8 | 6.7 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.8 | 4.1 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.8 | 6.5 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.8 | 3.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.8 | 17.5 | GO:0097386 | glial cell projection(GO:0097386) |
| 0.8 | 11.5 | GO:0005883 | neurofilament(GO:0005883) |
| 0.7 | 8.9 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.7 | 2.9 | GO:0070695 | FHF complex(GO:0070695) |
| 0.7 | 5.1 | GO:0043196 | varicosity(GO:0043196) |
| 0.7 | 8.7 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.7 | 2.1 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 0.7 | 4.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.7 | 13.2 | GO:0036038 | MKS complex(GO:0036038) |
| 0.7 | 1.4 | GO:0044308 | axonal spine(GO:0044308) |
| 0.7 | 50.5 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.6 | 4.5 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.6 | 35.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.6 | 13.9 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.6 | 7.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.6 | 5.5 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.6 | 37.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.6 | 2.4 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.6 | 4.1 | GO:0060091 | kinocilium(GO:0060091) |
| 0.6 | 5.9 | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) |
| 0.6 | 30.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.6 | 17.1 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.6 | 5.7 | GO:0043218 | compact myelin(GO:0043218) |
| 0.6 | 8.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.6 | 3.3 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.5 | 7.6 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.5 | 8.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.5 | 2.7 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.5 | 4.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.5 | 4.2 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.5 | 5.2 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.5 | 1.6 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.5 | 1.5 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.5 | 30.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.5 | 8.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.5 | 2.5 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.5 | 3.9 | GO:0072487 | MSL complex(GO:0072487) |
| 0.5 | 6.3 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.5 | 2.9 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.5 | 86.1 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.5 | 2.3 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.5 | 1.4 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 0.5 | 2.7 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.4 | 16.9 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.4 | 4.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.4 | 33.4 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.4 | 3.4 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.4 | 10.8 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.4 | 22.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.4 | 4.5 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.4 | 3.7 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.4 | 2.4 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.4 | 2.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.4 | 17.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.4 | 8.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.4 | 3.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.4 | 2.6 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.4 | 5.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.4 | 3.3 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.4 | 42.0 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.4 | 4.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.4 | 40.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.4 | 54.1 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.4 | 30.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.3 | 1.0 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.3 | 2.7 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.3 | 1.0 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 0.3 | 1.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.3 | 3.6 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.3 | 2.5 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.3 | 2.2 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.3 | 2.2 | GO:0097504 | SMN complex(GO:0032797) Gemini of coiled bodies(GO:0097504) |
| 0.3 | 2.7 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.3 | 5.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 2.1 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.3 | 4.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.3 | 1.8 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.3 | 14.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.3 | 3.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.3 | 53.4 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.3 | 7.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.3 | 1.1 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.3 | 5.5 | GO:0043679 | axon terminus(GO:0043679) |
| 0.3 | 3.8 | GO:0000800 | lateral element(GO:0000800) |
| 0.3 | 1.1 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.3 | 2.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.3 | 1.6 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.3 | 3.4 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.3 | 4.1 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.3 | 3.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.3 | 1.0 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.2 | 2.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.2 | 3.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.2 | 5.9 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.2 | 0.9 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 2.9 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.2 | 1.0 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.2 | 3.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 7.7 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.2 | 0.6 | GO:0098536 | deuterosome(GO:0098536) |
| 0.2 | 13.2 | GO:0098793 | presynapse(GO:0098793) |
| 0.2 | 2.4 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.2 | 2.0 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.2 | 2.8 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.2 | 0.9 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 4.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 2.3 | GO:0005921 | gap junction(GO:0005921) |
| 0.2 | 6.2 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.1 | 0.7 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
| 0.1 | 2.9 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 17.7 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 1.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 1.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 18.6 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.1 | 24.0 | GO:0005770 | late endosome(GO:0005770) |
| 0.1 | 1.9 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 2.8 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 0.1 | 18.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.1 | 0.6 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 0.3 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 3.8 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 2.5 | GO:0097546 | ciliary base(GO:0097546) |
| 0.1 | 1.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 0.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 5.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 7.1 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.1 | 1.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 1.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 1.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 10.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 1.0 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.7 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 1.5 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 1.1 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 6.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 12.4 | GO:0045202 | synapse(GO:0045202) |
| 0.1 | 9.0 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 1.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.5 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 13.2 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.1 | 0.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.6 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 2.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 2.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 1.4 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.0 | 1.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 46.2 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.7 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 1.1 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.2 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 0.1 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.0 | 0.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.1 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.9 | 29.6 | GO:0031696 | alpha-2C adrenergic receptor binding(GO:0031696) |
| 5.5 | 21.9 | GO:0032567 | dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567) |
| 5.4 | 21.6 | GO:0016880 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 5.0 | 15.0 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 4.9 | 14.8 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 4.9 | 63.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 4.5 | 13.4 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 4.5 | 17.9 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 4.0 | 12.1 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 3.9 | 11.7 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 3.9 | 15.6 | GO:0035939 | microsatellite binding(GO:0035939) |
| 3.7 | 14.6 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 3.5 | 10.6 | GO:0004336 | galactosylceramidase activity(GO:0004336) |
| 3.4 | 44.8 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 3.4 | 16.8 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 3.1 | 15.4 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 3.1 | 18.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 3.0 | 24.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 3.0 | 8.9 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 3.0 | 11.8 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 2.9 | 8.8 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 2.4 | 17.1 | GO:0000182 | rDNA binding(GO:0000182) |
| 2.4 | 38.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 2.3 | 13.8 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 2.2 | 6.7 | GO:0005135 | erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135) |
| 2.2 | 11.2 | GO:1903135 | cupric ion binding(GO:1903135) |
| 2.2 | 17.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 2.1 | 6.4 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 2.1 | 6.3 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 2.1 | 14.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 2.1 | 14.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 2.1 | 8.3 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 2.0 | 9.9 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 1.9 | 23.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 1.9 | 5.7 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 1.9 | 17.0 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.8 | 5.5 | GO:0004040 | amidase activity(GO:0004040) |
| 1.8 | 18.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 1.8 | 8.9 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 1.8 | 7.0 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 1.8 | 7.0 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 1.7 | 6.9 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 1.7 | 10.4 | GO:0070728 | leucine binding(GO:0070728) |
| 1.7 | 6.7 | GO:0018271 | biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271) |
| 1.7 | 6.7 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 1.6 | 1.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 1.6 | 4.9 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 1.6 | 4.8 | GO:0003826 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 1.5 | 4.5 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 1.5 | 4.4 | GO:0004577 | N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577) |
| 1.5 | 8.9 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 1.5 | 17.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 1.5 | 13.1 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 1.5 | 14.6 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 1.4 | 4.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 1.4 | 31.9 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 1.3 | 4.0 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 1.3 | 9.1 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 1.3 | 3.8 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 1.3 | 40.9 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 1.3 | 6.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 1.3 | 8.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 1.3 | 3.8 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 1.2 | 37.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 1.2 | 6.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 1.2 | 7.3 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 1.2 | 31.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 1.2 | 10.6 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 1.1 | 15.9 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 1.1 | 6.8 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 1.1 | 15.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 1.1 | 5.6 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 1.1 | 8.8 | GO:0015232 | heme transporter activity(GO:0015232) |
| 1.1 | 3.3 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 1.1 | 5.5 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
| 1.1 | 20.7 | GO:0031005 | filamin binding(GO:0031005) |
| 1.1 | 4.3 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 1.1 | 6.4 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 1.0 | 27.1 | GO:0046961 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 1.0 | 7.2 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 1.0 | 32.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 1.0 | 5.1 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 1.0 | 3.0 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 1.0 | 5.0 | GO:0052842 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 1.0 | 3.0 | GO:0070538 | oleic acid binding(GO:0070538) |
| 1.0 | 4.0 | GO:0015207 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 1.0 | 2.9 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.0 | 2.9 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
| 1.0 | 3.8 | GO:0050473 | arachidonate 15-lipoxygenase activity(GO:0050473) |
| 1.0 | 5.7 | GO:0015440 | peptide-transporting ATPase activity(GO:0015440) |
| 1.0 | 24.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.9 | 10.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.9 | 13.1 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.9 | 6.5 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.9 | 19.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.9 | 12.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.9 | 5.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.9 | 24.3 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.9 | 8.0 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.9 | 4.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.9 | 22.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.9 | 2.6 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.9 | 3.4 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.8 | 5.9 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.8 | 7.5 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.8 | 6.6 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.8 | 2.4 | GO:0052816 | medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816) |
| 0.8 | 8.1 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.8 | 4.8 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.8 | 3.2 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.8 | 4.7 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.8 | 3.9 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.8 | 12.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.8 | 21.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.7 | 22.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.7 | 3.7 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.7 | 3.0 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.7 | 2.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.7 | 18.7 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.7 | 3.5 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.7 | 2.1 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 0.7 | 2.7 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.7 | 2.0 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.7 | 2.0 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.7 | 6.5 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.6 | 2.5 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.6 | 1.8 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.6 | 17.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.6 | 12.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.6 | 3.5 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.6 | 8.2 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.6 | 15.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.6 | 18.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.6 | 7.0 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.6 | 4.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.6 | 9.0 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.6 | 7.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.5 | 3.8 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.5 | 4.9 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.5 | 2.7 | GO:0032181 | double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181) |
| 0.5 | 1.6 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.5 | 2.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.5 | 28.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.5 | 2.1 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.5 | 3.7 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.5 | 1.6 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 0.5 | 3.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.5 | 12.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.5 | 16.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.5 | 3.0 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.5 | 2.0 | GO:0047804 | cysteine-S-conjugate beta-lyase activity(GO:0047804) |
| 0.5 | 2.4 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.5 | 1.4 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.5 | 2.9 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.5 | 2.4 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 0.5 | 2.8 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.5 | 2.4 | GO:0000829 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.5 | 1.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.5 | 2.7 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.5 | 3.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.5 | 7.7 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.5 | 1.8 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.4 | 52.0 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.4 | 2.2 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.4 | 6.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.4 | 3.9 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.4 | 6.1 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.4 | 6.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 2.1 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.4 | 8.5 | GO:0005522 | profilin binding(GO:0005522) |
| 0.4 | 8.1 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.4 | 1.7 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.4 | 1.7 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.4 | 3.7 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.4 | 5.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.4 | 2.1 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.4 | 5.3 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.4 | 7.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.4 | 6.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.4 | 2.8 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.4 | 17.6 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.4 | 1.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.4 | 8.0 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.4 | 2.3 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.4 | 20.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 11.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.4 | 1.1 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.4 | 3.3 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.4 | 12.8 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.4 | 2.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.4 | 8.7 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.4 | 1.8 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.4 | 5.3 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.4 | 4.6 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.3 | 2.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.3 | 16.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.3 | 2.4 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.3 | 10.3 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.3 | 1.6 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 0.3 | 2.9 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.3 | 2.9 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.3 | 17.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.3 | 3.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.3 | 1.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.3 | 0.9 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.3 | 1.5 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.3 | 2.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.3 | 5.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.3 | 13.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.3 | 3.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.3 | 2.4 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.3 | 7.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.3 | 3.2 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.3 | 1.7 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.3 | 5.1 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.3 | 6.3 | GO:0005537 | mannose binding(GO:0005537) |
| 0.3 | 1.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.3 | 1.1 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.3 | 6.9 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.3 | 1.6 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.3 | 5.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.3 | 1.1 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375) |
| 0.3 | 5.8 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.3 | 2.1 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.3 | 3.7 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.3 | 1.0 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.3 | 3.9 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.3 | 1.6 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.3 | 8.6 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.3 | 1.0 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.3 | 3.1 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.3 | 1.8 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.3 | 9.4 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.3 | 1.0 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.3 | 3.3 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.3 | 1.3 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.3 | 1.0 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.2 | 1.0 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.2 | 2.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.2 | 3.9 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.2 | 1.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.2 | 4.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.2 | 0.9 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
| 0.2 | 10.9 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 6.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 1.4 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 1.1 | GO:0001093 | TFIIB-class transcription factor binding(GO:0001093) |
| 0.2 | 1.6 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.2 | 1.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 6.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.2 | 0.7 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.2 | 1.5 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.2 | 1.7 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.2 | 1.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.2 | 4.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 5.3 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.2 | 1.7 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.2 | 2.7 | GO:0019841 | retinol binding(GO:0019841) |
| 0.2 | 2.9 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.2 | 6.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 13.9 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.2 | 3.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 15.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.2 | 0.6 | GO:0008480 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.2 | 3.4 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.2 | 4.6 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 3.2 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.2 | 1.6 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 3.0 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.2 | 0.8 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.2 | 2.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.2 | 1.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.2 | 28.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.2 | 3.1 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.2 | 2.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.2 | 4.0 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.2 | 2.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.2 | 3.2 | GO:0031432 | titin binding(GO:0031432) |
| 0.2 | 12.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.2 | 18.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 3.1 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.2 | 6.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.2 | 2.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.2 | 8.8 | GO:0048029 | monosaccharide binding(GO:0048029) |
| 0.2 | 0.5 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 15.2 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.2 | 0.8 | GO:0019862 | IgA binding(GO:0019862) |
| 0.2 | 2.7 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.2 | 0.8 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.2 | 1.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.2 | 1.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.4 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.1 | 3.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 6.0 | GO:0005272 | sodium channel activity(GO:0005272) |
| 0.1 | 0.7 | GO:0047238 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
| 0.1 | 0.9 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 1.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 1.3 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.1 | 6.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 2.7 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.1 | 1.2 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.1 | 5.4 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 2.6 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.1 | 1.0 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 0.8 | GO:0015065 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 0.1 | 0.7 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.1 | 28.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 3.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 2.4 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.1 | 0.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 2.0 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.1 | 0.5 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 51.9 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.1 | 0.5 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 0.7 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.1 | 8.8 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 1.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 0.8 | GO:0005534 | galactose binding(GO:0005534) |
| 0.1 | 0.5 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.1 | 1.1 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 1.2 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 0.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.1 | 1.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.8 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.1 | 3.1 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 0.1 | 5.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.5 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 2.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 0.3 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 0.9 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.1 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.1 | 5.5 | GO:0004497 | monooxygenase activity(GO:0004497) |
| 0.1 | 3.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 4.2 | GO:0004620 | phospholipase activity(GO:0004620) |
| 0.1 | 1.5 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 1.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 2.2 | GO:0001099 | basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
| 0.0 | 7.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.3 | GO:0008443 | 6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443) |
| 0.0 | 2.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 1.4 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.8 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
| 0.0 | 0.8 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
| 0.0 | 1.0 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 1.1 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.1 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.0 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.0 | 1.8 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.4 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.0 | 0.1 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.0 | 2.9 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 1.0 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
| 0.0 | 0.3 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 0.8 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.0 | 0.1 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 0.7 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.7 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.0 | 6.7 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 2.6 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 3.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.7 | GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.3 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.9 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.0 | 0.0 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.1 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.0 | 0.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.4 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
| 0.0 | 0.7 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 0.1 | GO:0089720 | caspase binding(GO:0089720) |
| 0.0 | 0.1 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.0 | 0.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.3 | GO:0015179 | L-amino acid transmembrane transporter activity(GO:0015179) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 48.5 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 1.6 | 6.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 1.3 | 6.7 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 1.3 | 7.9 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 1.2 | 6.2 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 1.0 | 41.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 1.0 | 61.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.9 | 33.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.8 | 38.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.7 | 17.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.6 | 12.4 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.5 | 23.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.5 | 13.7 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.5 | 19.9 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.5 | 18.6 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.4 | 28.9 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.4 | 4.1 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.4 | 17.0 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.4 | 4.0 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.4 | 3.1 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.4 | 9.0 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.4 | 23.7 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.3 | 3.1 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.3 | 3.5 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.3 | 16.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.3 | 5.7 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.3 | 16.2 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.3 | 9.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.3 | 13.5 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.2 | 4.7 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.2 | 6.7 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.2 | 19.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.2 | 11.3 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 12.2 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 0.8 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.2 | 6.3 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.2 | 7.3 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.2 | 4.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 4.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.2 | 2.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.2 | 5.0 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.2 | 9.5 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 11.7 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.2 | 0.9 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.2 | 4.6 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.2 | 10.3 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.2 | 8.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 1.8 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 3.3 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 14.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 4.4 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 2.3 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 2.1 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 5.3 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 2.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 1.8 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 1.3 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 0.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 0.7 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 1.6 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 2.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 1.3 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.1 | 1.0 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 2.4 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 1.6 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.3 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 1.4 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 5.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 7.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.1 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.5 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 11.3 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 1.8 | 41.0 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 1.8 | 12.4 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 1.4 | 45.8 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 1.2 | 2.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 1.2 | 4.8 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 1.1 | 11.0 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 1.1 | 44.5 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 1.1 | 30.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 1.0 | 20.6 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 1.0 | 3.0 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.9 | 19.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.8 | 11.0 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.8 | 16.7 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.7 | 3.0 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.7 | 16.2 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.7 | 1.4 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.7 | 13.9 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.6 | 27.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.6 | 16.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.6 | 6.7 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.6 | 13.5 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.6 | 9.6 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.6 | 17.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.6 | 11.8 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.6 | 9.0 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.6 | 122.9 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.6 | 7.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.5 | 5.5 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.5 | 10.9 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.5 | 4.3 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.5 | 4.8 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.5 | 14.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.5 | 23.8 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.5 | 11.0 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.5 | 19.0 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.5 | 12.9 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.4 | 6.9 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.4 | 7.8 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.4 | 7.5 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.4 | 8.7 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.4 | 8.7 | REACTOME AQUAPORIN MEDIATED TRANSPORT | Genes involved in Aquaporin-mediated transport |
| 0.4 | 9.1 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.4 | 11.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.4 | 1.9 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.4 | 25.0 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.3 | 17.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.3 | 4.8 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.3 | 1.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.3 | 5.7 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.3 | 2.8 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.3 | 3.4 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.3 | 13.6 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.3 | 1.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.3 | 38.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.3 | 8.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 8.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 3.2 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 13.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 16.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.2 | 3.8 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 4.0 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.2 | 2.9 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.2 | 18.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.2 | 7.1 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.2 | 4.4 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.2 | 5.3 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.2 | 6.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 4.0 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.2 | 4.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 3.5 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.2 | 1.8 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.2 | 5.6 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.2 | 1.0 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 20.1 | REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.2 | 4.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.2 | 3.0 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 6.9 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 1.8 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.2 | 2.9 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 3.7 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 26.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 4.4 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 3.5 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.1 | 1.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 11.3 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.1 | 0.9 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.1 | 2.2 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 36.5 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 2.5 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.1 | 0.9 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.1 | 3.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 6.9 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.9 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.1 | 1.8 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 1.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 1.4 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.8 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 1.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.9 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 0.9 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 1.1 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 5.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 0.9 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 1.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 1.8 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.1 | 3.5 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 1.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 0.7 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.1 | 1.2 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.1 | 0.9 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 0.5 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 3.3 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 1.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 1.0 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 3.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.5 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.4 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.7 | REACTOME CD28 CO STIMULATION | Genes involved in CD28 co-stimulation |
| 0.0 | 0.7 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.8 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 1.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.2 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 1.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.1 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |