ISMARA results: MAFK

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MAFK

Z-value: 4.89

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Transcription factors associated with MAFK

Gene Symbol	Gene ID	Gene Info
MAFK Ensembl NCBI GeneCards UniProt	ENSG00000198517.10	MAFK

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MAFK	hg38_v1_chr7_+_1530684_1530726	0.31	4.1e-06	Click!

Activity profile of MAFK motif

Sorted Z-values of MAFK motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFK

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr1_+_198638968 Show fit	33.61	ENST00000348564.11 ENST00000530727.5 ENST00000442510.8 ENST00000645247.1 ENST00000367367.8 ENST00000367364.5 ENST00000413409.6	PTPRC Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type C
chr2_+_90021567 Show fit	31.92	ENST00000436451.2	IGKV6D-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-21 (non-functional)
chr2_+_88885397 Show fit	28.99	ENST00000390243.2	IGKV4-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 4-1
chr22_+_22906342 Show fit	25.56	ENST00000390325.2	IGLC3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr6_+_33075952 Show fit	24.49	ENST00000418931.7	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr2_+_89913982 Show fit	19.80	ENST00000390265.2	IGKV1D-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-33
chr14_-_106538331 Show fit	19.76	ENST00000390624.3	IGHV3-48 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-48
chr2_-_89027700 Show fit	19.13	ENST00000483158.1	IGKV3-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-11
chr1_-_169711603 Show fit	18.93	ENST00000236147.6 ENST00000650983.1	SELL Ensembl NCBI GeneCards UniProt Show fit	selectin L
chr2_-_89117844 Show fit	17.97	ENST00000490686.1	IGKV1-17 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-17
chr14_-_106185387 Show fit	17.62	ENST00000390605.2	IGHV1-18 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-18
chr6_-_25042003 Show fit	17.40	ENST00000510784.8	RIPOR2 Ensembl NCBI GeneCards UniProt Show fit	RHO family interacting cell polarization regulator 2
chr2_+_90159840 Show fit	16.64	ENST00000377032.5	IGKV1D-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr3_-_121660892 Show fit	16.12	ENST00000428394.6 ENST00000314583.8	HCLS1 Ensembl NCBI GeneCards UniProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr14_-_105626066 Show fit	15.92	ENST00000641978.1 ENST00000390543.3	IGHG4 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 4 (G4m marker)
chr21_-_10649835 Show fit	15.43	ENST00000622028.1	IGHV1OR21-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr22_-_17199609 Show fit	15.20	ENST00000330232.8	ADA2 Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase 2
chr1_+_158831323 Show fit	14.44	ENST00000368141.5	MNDA Ensembl NCBI GeneCards UniProt Show fit	myeloid cell nuclear differentiation antigen
chr2_+_90114838 Show fit	14.05	ENST00000417279.3	IGKV3D-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-15
chr12_+_69348372 Show fit	14.05	ENST00000261267.7 ENST00000549690.1 ENST00000548839.1	LYZ Ensembl NCBI GeneCards UniProt Show fit	lysozyme
chr5_+_55102635 Show fit	13.87	ENST00000274306.7	GZMA Ensembl NCBI GeneCards UniProt Show fit	granzyme A
chr1_-_145995713 Show fit	13.83	ENST00000425134.2	TXNIP Ensembl NCBI GeneCards UniProt Show fit	thioredoxin interacting protein
chr4_-_70666492 Show fit	13.27	ENST00000254801.9 ENST00000391614.7	JCHAIN Ensembl NCBI GeneCards UniProt Show fit	joining chain of multimeric IgA and IgM
chr14_-_106658251 Show fit	12.90	ENST00000454421.2	IGHV3-64 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr14_-_106235582 Show fit	12.79	ENST00000390607.2	IGHV3-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr2_-_89160329 Show fit	12.72	ENST00000390256.2	IGKV6-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6-21 (non-functional)
chr11_-_5227063 Show fit	12.66	ENST00000335295.4 ENST00000485743.1 ENST00000647020.1	HBB Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit beta
chr2_+_90172802 Show fit	12.64	ENST00000390277.3	IGKV3D-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-11
chr14_-_106025628 Show fit	12.63	ENST00000631943.1	IGHV7-4-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-4-1
chr6_+_32741382 Show fit	12.44	ENST00000374940.4	HLA-DQA2 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 2
chr14_-_106737547 Show fit	12.35	ENST00000632209.1	IGHV1-69-2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69-2
chr13_-_46182136 Show fit	12.12	ENST00000323076.7	LCP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 1
chr14_+_20955484 Show fit	11.85	ENST00000304625.3	RNASE2 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 2
chr1_-_89126066 Show fit	11.47	ENST00000370466.4	GBP2 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 2
chr13_+_30735523 Show fit	11.43	ENST00000380490.5	ALOX5AP Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr13_+_30713477 Show fit	11.15	ENST00000617770.4	ALOX5AP Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr6_+_6588082 Show fit	10.74	ENST00000379953.6	LY86 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 86
chr12_-_91153149 Show fit	10.70	ENST00000550758.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr18_+_24113341 Show fit	10.68	ENST00000540918.2	TTC39C Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 39C
chr14_-_106088573 Show fit	10.00	ENST00000632099.1	IGHV3-64D Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64D
chr7_+_50304693 Show fit	9.98	ENST00000331340.8 ENST00000413698.5 ENST00000612658.4 ENST00000359197.9 ENST00000349824.8 ENST00000343574.9 ENST00000357364.8 ENST00000440768.6 ENST00000346667.8 ENST00000615491.4	IKZF1 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 1
chr14_-_106422175 Show fit	9.85	ENST00000390619.2	IGHV4-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-39
chr3_+_122325237 Show fit	9.83	ENST00000264474.4 ENST00000479204.1	CSTA Ensembl NCBI GeneCards UniProt Show fit	cystatin A
chrX_-_107775740 Show fit	9.82	ENST00000372383.9	TSC22D3 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chrX_+_129779930 Show fit	9.60	ENST00000356892.4	SASH3 Ensembl NCBI GeneCards UniProt Show fit	SAM and SH3 domain containing 3
chr14_-_106811131 Show fit	9.47	ENST00000424969.2	IGHV3-74 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-74
chr2_+_89959979 Show fit	9.44	ENST00000453166.2	IGKV2D-28 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-28
chr14_-_95714088 Show fit	9.38	ENST00000556450.5	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chrX_-_107775951 Show fit	9.28	ENST00000315660.8 ENST00000372384.6 ENST00000502650.1 ENST00000506724.1	TSC22D3 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr1_-_206921867 Show fit	9.08	ENST00000628511.2 ENST00000367091.8	FCMR Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgM receptor
chr19_-_54281082 Show fit	8.96	ENST00000314446.10	LILRB2 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor B2
chr14_-_106557465 Show fit	8.94	ENST00000390625.3	IGHV3-49 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-49
chr14_-_95714114 Show fit	8.85	ENST00000402399.6 ENST00000555202.1	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr4_+_101813810 Show fit	8.80	ENST00000444316.2	BANK1 Ensembl NCBI GeneCards UniProt Show fit	B cell scaffold protein with ankyrin repeats 1
chrY_+_2841594 Show fit	8.76	ENST00000250784.13	RPS4Y1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S4 Y-linked 1
chr14_-_106062670 Show fit	8.69	ENST00000390598.2	IGHV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-7
chr17_-_78128630 Show fit	8.63	ENST00000306591.11	TMC6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel like 6
chr6_+_32844789 Show fit	8.60	ENST00000414474.5	PSMB9 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr14_-_95714146 Show fit	8.56	ENST00000554012.5	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr1_+_116754422 Show fit	8.53	ENST00000369478.4 ENST00000369477.1	CD2 Ensembl NCBI GeneCards UniProt Show fit	CD2 molecule
chr2_-_89222461 Show fit	8.46	ENST00000482769.1	IGKV2-28 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2-28
chr12_-_10130241 Show fit	8.44	ENST00000353231.9 ENST00000525605.1	CLEC7A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chr14_-_106622837 Show fit	8.30	ENST00000390628.3	IGHV1-58 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-58
chr2_-_89085787 Show fit	8.29	ENST00000390252.2	IGKV3-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-15
chr6_-_52763473 Show fit	8.28	ENST00000493422.3	GSTA2 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase alpha 2
chr3_-_39280432 Show fit	8.06	ENST00000542107.5 ENST00000435290.1	CX3CR1 Ensembl NCBI GeneCards UniProt Show fit	C-X3-C motif chemokine receptor 1
chr11_-_5243644 Show fit	8.03	ENST00000643122.1	HBD Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit delta
chr4_+_25160631 Show fit	8.02	ENST00000510415.1 ENST00000507794.2 ENST00000512921.4	SEPSECS-AS1 Ensembl NCBI GeneCards UniProt Show fit PI4K2B Ensembl NCBI GeneCards UniProt Show fit	SEPSECS antisense RNA 1 (head to head) phosphatidylinositol 4-kinase type 2 beta
chr2_+_90154073 Show fit	7.89	ENST00000611391.1	IGKV1D-13 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-13
chr14_-_106593319 Show fit	7.88	ENST00000390627.3	IGHV3-53 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-53
chr1_-_150765735 Show fit	7.82	ENST00000679898.1 ENST00000448301.7 ENST00000680664.1 ENST00000679512.1 ENST00000368985.8 ENST00000679582.1	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr11_+_72080313 Show fit	7.74	ENST00000307198.11 ENST00000538413.6 ENST00000642648.1 ENST00000289488.7	ENSG00000284922.2 Ensembl NCBI GeneCards UniProt Show fit LRTOMT Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing leucine rich transmembrane and O-methyltransferase domain containing
chr16_+_33009175 Show fit	7.58	ENST00000565407.2	IGHV3OR16-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr7_+_139829153 Show fit	7.56	ENST00000652056.1	TBXAS1 Ensembl NCBI GeneCards UniProt Show fit	thromboxane A synthase 1
chr15_-_19988117 Show fit	7.56	ENST00000558565.2	IGHV3OR15-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr1_-_206921987 Show fit	7.54	ENST00000530505.1 ENST00000442471.4	FCMR Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgM receptor
chr11_-_85665077 Show fit	7.54	ENST00000527447.2	CREBZF Ensembl NCBI GeneCards UniProt Show fit	CREB/ATF bZIP transcription factor
chr2_-_230225628 Show fit	7.43	ENST00000540870.5	SP110 Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr22_+_22811737 Show fit	7.39	ENST00000390315.3	IGLV3-10 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-10
chr12_-_10130143 Show fit	7.16	ENST00000298523.9 ENST00000396484.6 ENST00000310002.4 ENST00000304084.13	CLEC7A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 7A
chr2_+_230225718 Show fit	6.99	ENST00000420434.7 ENST00000392045.8 ENST00000417495.7 ENST00000343805.10	SP140 Ensembl NCBI GeneCards UniProt Show fit	SP140 nuclear body protein
chr2_-_89268506 Show fit	6.96	ENST00000473726.1	IGKV1-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-33
chr22_+_22704265 Show fit	6.80	ENST00000390307.2	IGLV3-22 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-22
chr14_-_106511856 Show fit	6.80	ENST00000390622.2	IGHV1-46 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-46
chr17_-_64390852 Show fit	6.78	ENST00000563924.6	PECAM1 Ensembl NCBI GeneCards UniProt Show fit	platelet and endothelial cell adhesion molecule 1
chr14_-_106875069 Show fit	6.67	ENST00000390639.2	IGHV7-81 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-81 (non-functional)
chr4_+_40192949 Show fit	6.66	ENST00000507851.5 ENST00000615577.4 ENST00000613272.4	RHOH Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member H
chr1_+_159005953 Show fit	6.53	ENST00000426592.6	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr12_-_7503744 Show fit	6.46	ENST00000396620.7 ENST00000432237.3	CD163 Ensembl NCBI GeneCards UniProt Show fit	CD163 molecule
chr1_-_158686700 Show fit	6.41	ENST00000643759.2	SPTA1 Ensembl NCBI GeneCards UniProt Show fit	spectrin alpha, erythrocytic 1
chr8_-_133060347 Show fit	6.39	ENST00000427060.6	SLA Ensembl NCBI GeneCards UniProt Show fit	Src like adaptor
chrX_+_71118515 Show fit	6.35	ENST00000333646.10	MED12 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 12
chr14_-_106277039 Show fit	6.24	ENST00000390610.2	IGHV1-24 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-24
chr1_+_159008978 Show fit	6.20	ENST00000447473.6	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr11_+_65879791 Show fit	6.20	ENST00000528419.6 ENST00000307886.8 ENST00000526034.2 ENST00000679584.1 ENST00000680443.1 ENST00000680670.1	CTSW Ensembl NCBI GeneCards UniProt Show fit	cathepsin W
chr2_+_89936859 Show fit	6.17	ENST00000474213.1	IGKV2D-30 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-30
chr2_+_89851723 Show fit	6.05	ENST00000429992.2	IGKV2D-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-40
chr14_-_75126964 Show fit	6.05	ENST00000678037.1 ENST00000553823.6 ENST00000678531.1 ENST00000238616.10	NEK9 Ensembl NCBI GeneCards UniProt Show fit	NIMA related kinase 9
chr1_+_89995102 Show fit	6.05	ENST00000340281.9 ENST00000361911.9 ENST00000370447.3	ZNF326 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 326
chr1_-_150765785 Show fit	6.00	ENST00000680311.1 ENST00000681728.1 ENST00000680288.1	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr19_-_54281145 Show fit	5.78	ENST00000434421.5 ENST00000391749.4	LILRB2 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor B2
chr4_+_69995958 Show fit	5.75	ENST00000381060.2 ENST00000246895.9	STATH Ensembl NCBI GeneCards UniProt Show fit	statherin
chr8_-_85341705 Show fit	5.64	ENST00000517618.5	CA1 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 1
chr17_-_78128731 Show fit	5.64	ENST00000592063.5 ENST00000590602.6 ENST00000589271.5	TMC6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel like 6
chr1_+_158845798 Show fit	5.57	ENST00000438394.1	MNDA Ensembl NCBI GeneCards UniProt Show fit	myeloid cell nuclear differentiation antigen
chr2_-_89297785 Show fit	5.56	ENST00000465170.1	IGKV1-37 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-37 (non-functional)
chr6_+_137871208 Show fit	5.47	ENST00000614035.4 ENST00000621150.3 ENST00000619035.4 ENST00000615468.4 ENST00000620204.3	TNFAIP3 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr7_+_139829242 Show fit	5.47	ENST00000455353.6 ENST00000458722.6 ENST00000448866.7 ENST00000411653.6	TBXAS1 Ensembl NCBI GeneCards UniProt Show fit	thromboxane A synthase 1
chr22_+_36913620 Show fit	5.46	ENST00000403662.8 ENST00000262825.9	CSF2RB Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 2 receptor subunit beta
chr12_+_12357056 Show fit	5.42	ENST00000314565.9 ENST00000542728.5	BORCS5 Ensembl NCBI GeneCards UniProt Show fit	BLOC-1 related complex subunit 5
chr6_+_31615215 Show fit	5.38	ENST00000337917.11 ENST00000376059.8	AIF1 Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1
chr13_-_99258366 Show fit	5.30	ENST00000397470.5 ENST00000397473.7	GPR18 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 18
chr17_-_64006880 Show fit	5.29	ENST00000449662.6	ICAM2 Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr5_+_55024250 Show fit	5.27	ENST00000231009.3	GZMK Ensembl NCBI GeneCards UniProt Show fit	granzyme K
chr4_-_56681288 Show fit	5.25	ENST00000556376.6 ENST00000420433.6	HOPX Ensembl NCBI GeneCards UniProt Show fit	HOP homeobox
chr14_-_106154113 Show fit	5.23	ENST00000390603.2	IGHV3-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-15
chr2_-_178807415 Show fit	5.22	ENST00000342992.10 ENST00000460472.6 ENST00000589042.5 ENST00000591111.5 ENST00000360870.10	TTN Ensembl NCBI GeneCards UniProt Show fit	titin
chr4_-_56681588 Show fit	5.15	ENST00000554144.5 ENST00000381260.7	HOPX Ensembl NCBI GeneCards UniProt Show fit	HOP homeobox
chr9_-_21368962 Show fit	5.13	ENST00000610660.1	IFNA13 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 13
chr15_-_79971164 Show fit	5.12	ENST00000335661.6 ENST00000267953.4 ENST00000677151.1	BCL2A1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 related protein A1
chr2_+_113406368 Show fit	5.11	ENST00000453673.3	IGKV1OR2-108 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr7_-_36724457 Show fit	5.10	ENST00000617537.5 ENST00000435386.1	AOAH Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase
chr6_-_32192630 Show fit	5.05	ENST00000375040.8	GPSM3 Ensembl NCBI GeneCards UniProt Show fit	G protein signaling modulator 3
chr6_-_49744434 Show fit	5.04	ENST00000433368.6 ENST00000354620.4	CRISP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich secretory protein 3
chr2_-_88947820 Show fit	5.03	ENST00000496168.1	IGKV1-5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr11_+_63536801 Show fit	4.99	ENST00000255688.8 ENST00000439013.6	PLAAT4 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A and acyltransferase 4
chr6_-_32192845 Show fit	4.99	ENST00000487761.5	GPSM3 Ensembl NCBI GeneCards UniProt Show fit	G protein signaling modulator 3
chr1_+_111139436 Show fit	4.98	ENST00000545121.5	CEPT1 Ensembl NCBI GeneCards UniProt Show fit	choline/ethanolamine phosphotransferase 1
chr4_+_174283886 Show fit	4.92	ENST00000457424.6 ENST00000503780.6 ENST00000514712.5	CEP44 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 44
chr1_+_26529745 Show fit	4.92	ENST00000374168.7 ENST00000374166.8	RPS6KA1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A1
chr11_-_57568276 Show fit	4.91	ENST00000340573.8	UBE2L6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L6
chr17_+_58238426 Show fit	4.91	ENST00000421678.6 ENST00000262290.9 ENST00000543544.5	LPO Ensembl NCBI GeneCards UniProt Show fit	lactoperoxidase
chr14_-_106627685 Show fit	4.90	ENST00000390629.3	IGHV4-59 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-59
chr12_-_96035571 Show fit	4.87	ENST00000228740.7	LTA4H Ensembl NCBI GeneCards UniProt Show fit	leukotriene A4 hydrolase
chr19_-_10380558 Show fit	4.86	ENST00000524462.5 ENST00000525621.6 ENST00000531836.5	TYK2 Ensembl NCBI GeneCards UniProt Show fit	tyrosine kinase 2
chr1_+_159015665 Show fit	4.86	ENST00000567661.5 ENST00000474473.1	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr3_+_111542178 Show fit	4.81	ENST00000283285.10 ENST00000352690.9	CD96 Ensembl NCBI GeneCards UniProt Show fit	CD96 molecule
chr21_+_38256984 Show fit	4.71	ENST00000398938.7	KCNJ15 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 15
chr12_-_91180365 Show fit	4.71	ENST00000547937.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr9_-_120914549 Show fit	4.70	ENST00000546084.5	TRAF1 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 1
chr12_+_10307950 Show fit	4.64	ENST00000543420.5 ENST00000543777.5	KLRD1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor D1
chr6_-_49744378 Show fit	4.62	ENST00000371159.8 ENST00000263045.9	CRISP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich secretory protein 3
chr8_+_2045037 Show fit	4.62	ENST00000262113.9	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr7_-_150632644 Show fit	4.61	ENST00000618759.4	GIMAP6 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 6
chr17_-_30824665 Show fit	4.60	ENST00000324238.7	CRLF3 Ensembl NCBI GeneCards UniProt Show fit	cytokine receptor like factor 3
chr5_-_140633167 Show fit	4.57	ENST00000302014.11	CD14 Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr19_-_41363930 Show fit	4.55	ENST00000675972.1	B9D2 Ensembl NCBI GeneCards UniProt Show fit	B9 domain containing 2
chr12_+_75391078 Show fit	4.42	ENST00000550916.6 ENST00000378692.7 ENST00000320460.8 ENST00000547164.1	GLIPR1L2 Ensembl NCBI GeneCards UniProt Show fit	GLIPR1 like 2
chr7_-_36724380 Show fit	4.37	ENST00000617267.4	AOAH Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase
chr15_-_55270383 Show fit	4.34	ENST00000396307.6	RAB27A Ensembl NCBI GeneCards UniProt Show fit	RAB27A, member RAS oncogene family
chr12_-_113335030 Show fit	4.32	ENST00000552014.5 ENST00000680972.1 ENST00000548186.5 ENST00000202831.7 ENST00000549181.5	SLC8B1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 8 member B1
chr12_+_10307818 Show fit	4.26	ENST00000350274.9 ENST00000336164.9	KLRD1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor D1
chr1_-_153041111 Show fit	4.24	ENST00000360379.4	SPRR2D Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 2D
chr1_+_159009886 Show fit	4.22	ENST00000340979.10 ENST00000368131.8 ENST00000295809.12 ENST00000368132.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chrX_+_124346544 Show fit	4.22	ENST00000371139.9	SH2D1A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr17_-_78128778 Show fit	4.20	ENST00000589553.5	TMC6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel like 6
chr2_+_98444835 Show fit	4.20	ENST00000409016.8 ENST00000409463.5 ENST00000074304.9 ENST00000409851.8 ENST00000409540.7	INPP4A Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type I A
chr8_+_2045058 Show fit	4.20	ENST00000523438.1	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr19_+_4791710 Show fit	4.19	ENST00000269856.5	FEM1A Ensembl NCBI GeneCards UniProt Show fit	fem-1 homolog A
chr13_-_48413105 Show fit	4.18	ENST00000620633.5	LPAR6 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 6
chr21_+_38256698 Show fit	4.18	ENST00000613499.4 ENST00000612702.4 ENST00000398925.5 ENST00000398928.5 ENST00000328656.8 ENST00000443341.5	KCNJ15 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 15
chr14_+_22450089 Show fit	4.15	ENST00000390473.1	TRDJ1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor delta joining 1
chrY_+_20575792 Show fit	4.12	ENST00000382772.3	EIF1AY Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A Y-linked
chr5_+_35856883 Show fit	4.08	ENST00000506850.5 ENST00000303115.8 ENST00000511982.1	IL7R Ensembl NCBI GeneCards UniProt Show fit	interleukin 7 receptor
chr11_+_6863057 Show fit	4.08	ENST00000641461.1	OR10A2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily A member 2
chr1_-_226739271 Show fit	4.06	ENST00000429204.6 ENST00000366784.1	ITPKB Ensembl NCBI GeneCards UniProt Show fit	inositol-trisphosphate 3-kinase B
chr5_+_157180816 Show fit	4.04	ENST00000422843.8	ITK Ensembl NCBI GeneCards UniProt Show fit	IL2 inducible T cell kinase
chr1_+_159010002 Show fit	4.03	ENST00000359709.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr6_-_41941795 Show fit	4.02	ENST00000372991.9	CCND3 Ensembl NCBI GeneCards UniProt Show fit	cyclin D3
chrY_+_20575716 Show fit	4.01	ENST00000361365.7	EIF1AY Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A Y-linked
chr12_-_9115907 Show fit	3.97	ENST00000318602.12	A2M Ensembl NCBI GeneCards UniProt Show fit	alpha-2-macroglobulin
chr16_-_25015311 Show fit	3.89	ENST00000303665.9 ENST00000455311.6 ENST00000289968.11	ARHGAP17 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 17
chr13_-_106568107 Show fit	3.86	ENST00000400198.8	ARGLU1 Ensembl NCBI GeneCards UniProt Show fit	arginine and glutamate rich 1
chr4_+_70430487 Show fit	3.85	ENST00000413702.5	MUC7 Ensembl NCBI GeneCards UniProt Show fit	mucin 7, secreted
chr12_-_7503841 Show fit	3.84	ENST00000359156.8	CD163 Ensembl NCBI GeneCards UniProt Show fit	CD163 molecule
chr15_-_56245074 Show fit	3.82	ENST00000674082.1	RFX7 Ensembl NCBI GeneCards UniProt Show fit	regulatory factor X7
chr5_+_157269317 Show fit	3.79	ENST00000618329.4	CYFIP2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic FMR1 interacting protein 2
chr3_+_44338119 Show fit	3.73	ENST00000383746.7 ENST00000417237.5	TCAIM Ensembl NCBI GeneCards UniProt Show fit	T cell activation inhibitor, mitochondrial
chr10_+_71319249 Show fit	3.71	ENST00000373189.6 ENST00000479577.2	SLC29A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 29 member 3
chr19_-_54364983 Show fit	3.70	ENST00000434277.6	LAIR1 Ensembl NCBI GeneCards UniProt Show fit	leukocyte associated immunoglobulin like receptor 1
chr9_+_89318811 Show fit	3.68	ENST00000534113.6	SECISBP2 Ensembl NCBI GeneCards UniProt Show fit	SECIS binding protein 2
chr8_+_132866948 Show fit	3.68	ENST00000220616.9	TG Ensembl NCBI GeneCards UniProt Show fit	thyroglobulin
chr14_-_106360320 Show fit	3.67	ENST00000390615.2	IGHV3-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-33
chr19_+_41884370 Show fit	3.67	ENST00000378152.8 ENST00000337665.8	ARHGEF1 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 1
chr10_+_46375645 Show fit	3.63	ENST00000622769.4	ANXA8L1 Ensembl NCBI GeneCards UniProt Show fit	annexin A8 like 1
chr1_-_153057504 Show fit	3.61	ENST00000392653.3	SPRR2A Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 2A
chrX_+_71118576 Show fit	3.61	ENST00000374080.8	MED12 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 12
chr7_+_80638662 Show fit	3.60	ENST00000394788.7	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr18_-_55351977 Show fit	3.59	ENST00000643689.1	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr19_-_14778552 Show fit	3.57	ENST00000315576.8	ADGRE2 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor E2
chr16_-_67936808 Show fit	3.56	ENST00000358514.9	PSMB10 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 10
chr20_+_63733219 Show fit	3.55	ENST00000632538.1	ENSG00000273154.3 Ensembl NCBI GeneCards UniProt Show fit	novel protein, ZGPAT-LIME1 readthrough
chr14_+_61187544 Show fit	3.53	ENST00000555185.5 ENST00000557294.5 ENST00000556778.5	PRKCH Ensembl NCBI GeneCards UniProt Show fit	protein kinase C eta
chr8_+_95133746 Show fit	3.50	ENST00000315367.4	PLEKHF2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and FYVE domain containing 2
chr12_-_10454485 Show fit	3.50	ENST00000408006.7 ENST00000544822.2 ENST00000536188.5	KLRC1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor C1
chr14_-_90331904 Show fit	3.49	ENST00000628832.1 ENST00000354366.8	NRDE2 Ensembl NCBI GeneCards UniProt Show fit	NRDE-2, necessary for RNA interference, domain containing
chr14_+_20891385 Show fit	3.48	ENST00000304639.4	RNASE3 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 3
chr7_+_150567347 Show fit	3.45	ENST00000461940.5	GIMAP4 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 4
chrX_+_12975083 Show fit	3.43	ENST00000451311.7 ENST00000380636.1	TMSB4X Ensembl NCBI GeneCards UniProt Show fit	thymosin beta 4 X-linked
chr11_+_57597563 Show fit	3.41	ENST00000619430.2 ENST00000457869.1 ENST00000340687.10 ENST00000278407.9 ENST00000378323.8 ENST00000378324.6 ENST00000403558.1	SERPING1 Ensembl NCBI GeneCards UniProt Show fit	serpin family G member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.2	33.6	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
4.6	13.8	GO:0034769	basement membrane disassembly(GO:0034769)
4.2	12.7	GO:0030185	nitric oxide transport(GO:0030185)
3.5	17.4	GO:1903904	negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
3.0	15.2	GO:0046103	adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
2.8	14.0	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
2.6	7.9	GO:0038156	interleukin-3-mediated signaling pathway(GO:0038156)
2.5	7.4	GO:0001868	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.4	19.1	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
2.4	346.3	GO:0006958	complement activation, classical pathway(GO:0006958)
2.4	7.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
2.1	6.2	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
2.0	8.1	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.9	7.8	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
1.9	25.0	GO:2001300	lipoxin metabolic process(GO:2001300)
1.9	13.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
1.9	13.2	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
1.9	5.6	GO:0002304	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.9	5.6	GO:1900195	positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.8	14.7	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.7	6.8	GO:0050904	diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
1.7	5.1	GO:1902846	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.6	3.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
1.5	16.9	GO:0071726	toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
1.5	16.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
1.5	16.0	GO:0032074	negative regulation of nuclease activity(GO:0032074)
1.4	1.4	GO:0032661	regulation of interleukin-18 production(GO:0032661)
1.3	1.3	GO:0060459	left lung development(GO:0060459)
1.3	2.6	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
1.3	5.2	GO:0051697	protein delipidation(GO:0051697)
1.3	5.1	GO:0010430	fatty acid omega-oxidation(GO:0010430)
1.2	8.7	GO:1903433	regulation of constitutive secretory pathway(GO:1903433)
1.2	16.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.2	2.4	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
1.2	8.5	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
1.2	4.8	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
1.2	10.7	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.2	18.7	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
1.1	6.8	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
1.1	7.9	GO:0014900	muscle hyperplasia(GO:0014900)
1.1	8.8	GO:0002074	extraocular skeletal muscle development(GO:0002074)
1.1	3.2	GO:2000538	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
1.1	3.2	GO:2001226	negative regulation of chloride transport(GO:2001226)
1.0	2.1	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
1.0	4.1	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.0	22.9	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
1.0	2.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
1.0	9.8	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
1.0	15.6	GO:0006910	phagocytosis, recognition(GO:0006910)
0.9	2.8	GO:0036049	protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
0.9	32.3	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.9	2.7	GO:0036233	glycine import(GO:0036233)
0.9	3.5	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.9	2.6	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.8	3.3	GO:0015722	canalicular bile acid transport(GO:0015722)
0.8	1.6	GO:0071336	submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.8	2.3	GO:1900275	negative regulation of phospholipase C activity(GO:1900275)
0.7	3.0	GO:0001555	oocyte growth(GO:0001555)
0.7	2.2	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.7	2.2	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.7	111.1	GO:0002377	immunoglobulin production(GO:0002377)
0.7	4.9	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.7	2.8	GO:0035627	ceramide transport(GO:0035627)
0.7	4.2	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7	2.1	GO:0018094	protein polyglycylation(GO:0018094)
0.7	4.1	GO:0033029	neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.7	11.4	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.7	2.7	GO:0036369	transcription factor catabolic process(GO:0036369)
0.7	10.0	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.7	3.3	GO:0019835	cytolysis(GO:0019835)
0.6	1.9	GO:0035565	regulation of pronephros size(GO:0035565)
0.6	1.9	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.6	8.8	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6	3.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.6	13.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.6	1.8	GO:0072709	cellular response to sorbitol(GO:0072709)
0.6	4.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.6	1.8	GO:0044565	dendritic cell proliferation(GO:0044565)
0.6	13.6	GO:0002347	response to tumor cell(GO:0002347)
0.6	1.8	GO:0090234	regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.6	1.2	GO:0003290	atrial septum secundum morphogenesis(GO:0003290)
0.6	4.1	GO:0001550	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.6	26.1	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.6	2.9	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.6	2.9	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.6	2.3	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.6	5.8	GO:0046541	saliva secretion(GO:0046541)
0.6	2.3	GO:0046968	peptide antigen transport(GO:0046968)
0.6	7.3	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.6	22.9	GO:0018149	peptide cross-linking(GO:0018149)
0.6	1.7	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.5	3.8	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5	9.3	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.5	1.5	GO:2000360	negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.5	5.6	GO:0006657	CDP-choline pathway(GO:0006657)
0.5	2.0	GO:0090467	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.5	1.5	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.5	3.5	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5	4.0	GO:0015705	iodide transport(GO:0015705)
0.5	18.9	GO:0033198	response to ATP(GO:0033198)
0.5	10.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.5	3.0	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.5	3.3	GO:0044245	polysaccharide digestion(GO:0044245)
0.5	23.0	GO:0032729	positive regulation of interferon-gamma production(GO:0032729)
0.5	4.2	GO:0001865	NK T cell differentiation(GO:0001865)
0.5	2.8	GO:0034587	piRNA metabolic process(GO:0034587)
0.5	0.9	GO:0031959	mineralocorticoid receptor signaling pathway(GO:0031959)
0.5	0.9	GO:0007525	somatic muscle development(GO:0007525)
0.4	1.3	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4	2.6	GO:1904304	regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.4	4.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.4	2.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.4	2.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4	1.7	GO:0071896	protein localization to adherens junction(GO:0071896)
0.4	1.7	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.4	2.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.4	2.0	GO:0006574	valine catabolic process(GO:0006574)
0.4	8.2	GO:0005513	detection of calcium ion(GO:0005513)
0.4	1.6	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.4	1.1	GO:0033685	negative regulation of luteinizing hormone secretion(GO:0033685)
0.4	1.1	GO:0071812	circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.4	1.5	GO:0030806	negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.4	1.1	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.4	1.8	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4	1.4	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.4	1.1	GO:0014062	regulation of serotonin secretion(GO:0014062)
0.3	3.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.3	2.1	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.3	1.4	GO:0048807	ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.3	2.7	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3	2.4	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.3	3.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.3	4.6	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.3	1.9	GO:0032196	transposition(GO:0032196)
0.3	3.2	GO:0032264	IMP salvage(GO:0032264)
0.3	5.7	GO:0015671	oxygen transport(GO:0015671)
0.3	2.2	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3	0.9	GO:1901053	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.3	0.6	GO:0015669	gas transport(GO:0015669)
0.3	2.7	GO:0032790	ribosome disassembly(GO:0032790)
0.3	2.4	GO:0070995	NADPH oxidation(GO:0070995)
0.3	1.7	GO:0006710	androgen catabolic process(GO:0006710)
0.3	1.2	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.3	0.9	GO:0042412	taurine biosynthetic process(GO:0042412)
0.3	1.4	GO:0014056	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056)
0.3	4.5	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.3	2.5	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3	2.8	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.3	1.3	GO:1901911	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3	2.7	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.3	1.3	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.3	17.0	GO:0006968	cellular defense response(GO:0006968)
0.3	1.6	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.3	2.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.3	0.8	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.3	19.6	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.2	2.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.2	2.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2	2.0	GO:0030091	protein repair(GO:0030091)
0.2	0.7	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2	0.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2	1.7	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.2	10.5	GO:0010107	potassium ion import(GO:0010107)
0.2	1.9	GO:0051414	response to cortisol(GO:0051414)
0.2	4.6	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2	1.6	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	3.0	GO:0015074	DNA integration(GO:0015074)
0.2	0.8	GO:1905065	positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.2	1.7	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.2	1.6	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2	3.9	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.2	1.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.2	2.4	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.2	0.8	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.2	2.4	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.2	2.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.2	6.4	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.2	2.5	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.2	1.9	GO:0046689	response to mercury ion(GO:0046689)
0.2	1.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	0.2	GO:1903487	regulation of lactation(GO:1903487)
0.2	2.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.8	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.2	48.5	GO:0002250	adaptive immune response(GO:0002250)
0.2	3.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2	0.5	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2	1.4	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	13.5	GO:0031295	T cell costimulation(GO:0031295)
0.2	2.7	GO:0046688	response to copper ion(GO:0046688)
0.2	1.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.2	1.1	GO:0061366	negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2	1.1	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.2	1.4	GO:0008272	sulfate transport(GO:0008272)
0.2	1.4	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.2	1.7	GO:0008298	intracellular mRNA localization(GO:0008298)
0.2	6.2	GO:0006953	acute-phase response(GO:0006953)
0.2	8.0	GO:0045576	mast cell activation(GO:0045576)
0.2	2.0	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.1	11.7	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.1	2.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.6	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	2.1	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.4	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.1	1.3	GO:0051026	chiasma assembly(GO:0051026)
0.1	1.0	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.9	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	1.0	GO:0015886	heme transport(GO:0015886)
0.1	1.3	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.7	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.8	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	2.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	2.1	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	1.4	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	2.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	1.5	GO:2000303	regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1	0.7	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1	0.5	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.1	0.4	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	12.4	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1	1.7	GO:0006449	regulation of translational termination(GO:0006449)
0.1	3.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.1	3.6	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	2.9	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	3.9	GO:0060384	innervation(GO:0060384)
0.1	0.6	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1	1.2	GO:0032754	positive regulation of interleukin-5 production(GO:0032754)
0.1	0.7	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	1.6	GO:0048793	pronephros development(GO:0048793)
0.1	6.8	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1	33.4	GO:0006413	translational initiation(GO:0006413)
0.1	4.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	2.6	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	2.0	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.6	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	4.4	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1	1.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	1.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.5	GO:0040030	regulation of molecular function, epigenetic(GO:0040030)
0.1	0.6	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.1	0.6	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	0.2	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	1.0	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	1.7	GO:0002228	natural killer cell mediated immunity(GO:0002228)
0.1	0.5	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	6.1	GO:0007032	endosome organization(GO:0007032)
0.1	1.2	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.3	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1	5.1	GO:0001836	release of cytochrome c from mitochondria(GO:0001836)
0.1	1.0	GO:0055091	phospholipid homeostasis(GO:0055091)
0.1	1.1	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148) phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1	1.8	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	8.0	GO:0051291	protein heterooligomerization(GO:0051291)
0.1	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.2	GO:0030573	bile acid catabolic process(GO:0030573)
0.1	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	4.3	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	1.0	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1	0.3	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.1	0.8	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.6	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	1.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	0.7	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.1	2.5	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.1	1.0	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.4	GO:0071104	response to interleukin-9(GO:0071104)
0.1	0.7	GO:0006702	androgen biosynthetic process(GO:0006702)
0.1	0.2	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.1	0.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.9	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	6.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	0.1	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.1	0.4	GO:1903282	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.1	1.0	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	1.0	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.1	0.2	GO:0097283	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1	1.6	GO:1903557	positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.1	1.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	3.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	2.7	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
0.1	1.4	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.1	0.6	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.1	GO:0016999	antibiotic metabolic process(GO:0016999)
0.1	2.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	0.4	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1	1.5	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.1	0.7	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	2.1	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1	1.7	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.4	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	3.8	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.4	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.6	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	1.3	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.2	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0	0.1	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.0	1.6	GO:0001541	ovarian follicle development(GO:0001541)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	1.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.7	GO:0032418	lysosome localization(GO:0032418)
0.0	0.4	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.2	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.4	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	1.8	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	2.7	GO:0071222	cellular response to lipopolysaccharide(GO:0071222)
0.0	0.6	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	1.6	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.3	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.2	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.8	GO:0007398	ectoderm development(GO:0007398)
0.0	1.6	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
0.0	0.8	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.5	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	2.1	GO:0030282	bone mineralization(GO:0030282)
0.0	0.1	GO:0045837	negative regulation of mitochondrial membrane potential(GO:0010917) mitochondrial protein catabolic process(GO:0035694) negative regulation of membrane potential(GO:0045837)
0.0	0.2	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	1.5	GO:0098869	cellular oxidant detoxification(GO:0098869)
0.0	0.6	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	1.6	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.9	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.9	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.4	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.0	0.9	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.8	GO:0021983	pituitary gland development(GO:0021983)
0.0	0.6	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.4	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:2000347	positive regulation of hepatocyte proliferation(GO:2000347)
0.0	0.1	GO:0072574	hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575) liver morphogenesis(GO:0072576)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.3	GO:0097502	mannosylation(GO:0097502)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	1.5	GO:0017148	negative regulation of translation(GO:0017148)
0.0	0.2	GO:0044458	motile cilium assembly(GO:0044458)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	13.3	GO:0071753	dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
3.2	12.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
2.7	128.7	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
2.1	14.5	GO:0036021	endolysosome lumen(GO:0036021)
2.0	6.0	GO:0044609	DBIRD complex(GO:0044609)
1.9	36.9	GO:0042613	MHC class II protein complex(GO:0042613)
1.7	12.2	GO:1990111	spermatoproteasome complex(GO:1990111)
1.7	5.1	GO:0061673	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
1.6	17.4	GO:0060171	stereocilium membrane(GO:0060171)
1.4	5.4	GO:0005873	plus-end kinesin complex(GO:0005873)
1.3	3.9	GO:0097679	other organism cytoplasm(GO:0097679)
1.2	15.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1	6.4	GO:0032437	cuticular plate(GO:0032437)
1.0	176.4	GO:0072562	blood microparticle(GO:0072562)
1.0	8.7	GO:0070652	HAUS complex(GO:0070652)
1.0	2.9	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.8	1.6	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.8	2.3	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.7	2.2	GO:0043159	acrosomal matrix(GO:0043159)
0.7	2.8	GO:0071546	pi-body(GO:0071546)
0.7	2.7	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.7	17.5	GO:0001891	phagocytic cup(GO:0001891)
0.6	3.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.6	6.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.6	3.6	GO:1990769	proximal neuron projection(GO:1990769)
0.6	7.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.6	4.4	GO:0072487	MSL complex(GO:0072487)
0.5	10.2	GO:0036038	MKS complex(GO:0036038)
0.5	6.9	GO:0033093	Weibel-Palade body(GO:0033093)
0.5	1.6	GO:0044393	microspike(GO:0044393)
0.5	2.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.5	1.5	GO:0030312	external encapsulating structure(GO:0030312)
0.5	4.6	GO:0001520	outer dense fiber(GO:0001520)
0.5	4.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.5	4.4	GO:0044294	dendritic growth cone(GO:0044294)
0.5	2.0	GO:1990393	3M complex(GO:1990393)
0.5	4.3	GO:0030061	mitochondrial crista(GO:0030061)
0.5	16.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.5	5.6	GO:0005677	chromatin silencing complex(GO:0005677)
0.4	11.6	GO:0032982	myosin filament(GO:0032982)
0.4	2.3	GO:0045298	tubulin complex(GO:0045298)
0.4	2.6	GO:0097209	epidermal lamellar body(GO:0097209)
0.4	2.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.4	2.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.4	1.4	GO:0042643	actomyosin, actin portion(GO:0042643)
0.3	35.8	GO:0070821	tertiary granule membrane(GO:0070821)
0.3	43.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.3	4.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.3	5.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3	5.0	GO:0031089	platelet dense granule lumen(GO:0031089)
0.3	3.1	GO:0042587	glycogen granule(GO:0042587)
0.3	1.4	GO:0030314	junctional membrane complex(GO:0030314)
0.3	12.7	GO:0001533	cornified envelope(GO:0001533)
0.3	1.3	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	1.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.2	3.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	17.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	1.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	0.7	GO:0035517	PR-DUB complex(GO:0035517)
0.2	0.7	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2	2.2	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	67.2	GO:0009897	external side of plasma membrane(GO:0009897)
0.2	2.6	GO:0097524	sperm plasma membrane(GO:0097524)
0.2	3.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2	8.8	GO:0016592	mediator complex(GO:0016592)
0.2	2.6	GO:0017119	Golgi transport complex(GO:0017119)
0.2	1.8	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2	2.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.2	2.6	GO:0031045	dense core granule(GO:0031045)
0.2	2.9	GO:0045277	respiratory chain complex IV(GO:0045277)
0.2	1.1	GO:0002177	manchette(GO:0002177)
0.2	7.5	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.2	4.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.2	3.6	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.7	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	2.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	1.2	GO:0071953	elastic fiber(GO:0071953)
0.1	1.6	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	3.0	GO:0005720	nuclear heterochromatin(GO:0005720)
0.1	0.8	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.3	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1	1.3	GO:0030008	TRAPP complex(GO:0030008)
0.1	1.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	1.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	1.3	GO:0071203	WASH complex(GO:0071203)
0.1	1.0	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.9	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.3	GO:0097224	sperm connecting piece(GO:0097224)
0.1	1.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.7	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	2.5	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.6	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	1.7	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	2.9	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	110.5	GO:0005615	extracellular space(GO:0005615)
0.1	0.5	GO:0030905	retromer, tubulation complex(GO:0030905)
0.1	1.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.8	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.1	2.6	GO:0002102	podosome(GO:0002102)
0.1	0.2	GO:0005927	muscle tendon junction(GO:0005927)
0.1	2.6	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.3	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	3.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	1.5	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	0.4	GO:0097486	late endosome lumen(GO:0031906) multivesicular body lumen(GO:0097486)
0.1	2.1	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	1.0	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	1.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.8	GO:0043194	axon initial segment(GO:0043194)
0.0	6.2	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	5.9	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.2	GO:0071439	clathrin complex(GO:0071439)
0.0	0.9	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	2.0	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	12.4	GO:0016607	nuclear speck(GO:0016607)
0.0	0.8	GO:0034451	centriolar satellite(GO:0034451)
0.0	4.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.3	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.5	GO:0000421	autophagosome membrane(GO:0000421)
0.0	2.6	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.7	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	1.7	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	3.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.5	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.5	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	22.6	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
4.3	13.0	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
4.3	12.8	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
3.8	18.9	GO:0043208	glycosphingolipid binding(GO:0043208)
3.0	23.6	GO:0023029	MHC class Ib protein binding(GO:0023029)
2.6	7.9	GO:0004912	interleukin-3 receptor activity(GO:0004912)
2.6	12.8	GO:0032395	MHC class II receptor activity(GO:0032395)
2.4	11.8	GO:0004522	ribonuclease A activity(GO:0004522)
2.4	141.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
2.3	14.0	GO:0003796	lysozyme activity(GO:0003796)
2.2	6.6	GO:0046848	hydroxyapatite binding(GO:0046848)
2.1	19.1	GO:0043426	MRF binding(GO:0043426)
2.1	382.4	GO:0003823	antigen binding(GO:0003823)
2.0	8.1	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
1.9	5.6	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.8	12.7	GO:0030492	hemoglobin binding(GO:0030492)
1.7	5.0	GO:0001861	complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
1.7	5.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
1.6	4.8	GO:0030350	iron-responsive element binding(GO:0030350)
1.5	12.3	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
1.5	13.2	GO:0031685	adenosine receptor binding(GO:0031685)
1.4	4.2	GO:0031862	prostanoid receptor binding(GO:0031862)
1.4	8.4	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.3	4.0	GO:0019959	interleukin-8 binding(GO:0019959)
1.3	5.1	GO:0004031	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
1.2	7.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
1.1	6.9	GO:0071723	lipopeptide binding(GO:0071723)
1.1	3.3	GO:0004556	alpha-amylase activity(GO:0004556)
1.1	2.2	GO:0042806	fucose binding(GO:0042806)
1.0	3.1	GO:0052852	(S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
1.0	3.0	GO:0005174	CD40 receptor binding(GO:0005174)
1.0	4.9	GO:0042296	ISG15 transferase activity(GO:0042296)
0.9	2.8	GO:0061697	protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.9	9.3	GO:0004064	arylesterase activity(GO:0004064)
0.9	2.8	GO:0097001	ceramide binding(GO:0097001)
0.9	15.6	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.9	7.7	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.9	27.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.8	2.5	GO:0016803	ether hydrolase activity(GO:0016803)
0.8	2.4	GO:0015265	urea channel activity(GO:0015265)
0.8	28.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.7	2.2	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.7	3.5	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.7	15.4	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.7	4.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.7	2.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.7	11.8	GO:0042809	vitamin D receptor binding(GO:0042809)
0.6	1.9	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.6	3.2	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.6	2.5	GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.6	22.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.6	6.0	GO:0051011	microtubule minus-end binding(GO:0051011)
0.6	2.3	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.6	1.7	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.6	4.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6	2.9	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.6	3.4	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.5	3.7	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.5	3.1	GO:0016416	O-palmitoyltransferase activity(GO:0016416)
0.5	14.5	GO:0001968	fibronectin binding(GO:0001968)
0.5	1.5	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5	3.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5	2.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.5	2.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.5	5.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.5	2.3	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.5	8.9	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5	2.3	GO:0008410	CoA-transferase activity(GO:0008410)
0.4	2.6	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4	2.6	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4	2.5	GO:0004630	phospholipase D activity(GO:0004630)
0.4	1.6	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4	2.0	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.4	5.5	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.4	4.3	GO:0051525	NFAT protein binding(GO:0051525)
0.4	2.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4	1.5	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.4	2.7	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.4	1.9	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.4	1.1	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4	4.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.4	1.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.4	1.1	GO:0016497	substance K receptor activity(GO:0016497)
0.4	1.9	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.4	6.3	GO:0031996	thioesterase binding(GO:0031996)
0.4	2.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.4	3.6	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4	0.7	GO:0004040	amidase activity(GO:0004040)
0.4	2.9	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4	3.6	GO:0005549	odorant binding(GO:0005549)
0.4	1.8	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.4	3.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4	2.5	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3	1.4	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.3	1.0	GO:0001847	opsonin receptor activity(GO:0001847)
0.3	4.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.3	4.4	GO:0005131	growth hormone receptor binding(GO:0005131)
0.3	4.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.3	1.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	8.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.3	0.9	GO:0052816	medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.3	0.9	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3	3.0	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.3	2.9	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3	0.9	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.3	2.0	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3	0.8	GO:0061609	fructose-1-phosphate aldolase activity(GO:0061609)
0.3	2.7	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3	1.3	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3	5.1	GO:0051400	BH domain binding(GO:0051400)
0.3	1.3	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.3	0.8	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.3	1.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.3	2.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3	7.9	GO:0043015	gamma-tubulin binding(GO:0043015)
0.2	5.2	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.7	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2	1.5	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.2	5.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	1.7	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	2.6	GO:0019957	C-C chemokine binding(GO:0019957)
0.2	6.1	GO:0031489	myosin V binding(GO:0031489)
0.2	4.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.2	16.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	2.4	GO:0019864	IgG binding(GO:0019864)
0.2	1.4	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2	12.0	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.2	1.8	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	2.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.2	3.5	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.2	4.2	GO:0008494	translation activator activity(GO:0008494)
0.2	5.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	2.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	0.9	GO:0017018	myosin phosphatase activity(GO:0017018)
0.2	1.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.2	0.7	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.2	0.3	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.2	14.9	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2	2.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2	4.5	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2	1.1	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2	0.6	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	2.8	GO:0005522	profilin binding(GO:0005522)
0.2	1.8	GO:0050700	CARD domain binding(GO:0050700)
0.2	0.8	GO:0004126	cytidine deaminase activity(GO:0004126)
0.2	3.2	GO:0048018	receptor agonist activity(GO:0048018)
0.2	0.8	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.1	2.5	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	1.0	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	4.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	2.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1	0.7	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	2.0	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.1	0.6	GO:0035500	MH2 domain binding(GO:0035500)
0.1	1.4	GO:0036310	annealing helicase activity(GO:0036310)
0.1	1.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	2.6	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	2.0	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	1.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.6	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.6	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	1.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	1.1	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	4.8	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0017129	triglyceride binding(GO:0017129)
0.1	11.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	1.8	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.1	1.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	4.0	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	0.2	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	1.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.9	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	1.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.6	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.1	2.9	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	17.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	6.8	GO:0008200	ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.1	0.5	GO:1990460	leptin receptor binding(GO:1990460)
0.1	1.3	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.4	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	4.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0080084	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.1	2.5	GO:0008009	chemokine activity(GO:0008009)
0.1	2.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	11.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	1.4	GO:0017136	NAD-dependent histone deacetylase activity(GO:0017136)
0.1	0.7	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.1	0.4	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	4.4	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	0.4	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1	1.8	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	0.6	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1	0.8	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	0.6	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	2.2	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	4.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	14.0	GO:0051015	actin filament binding(GO:0051015)
0.1	14.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	3.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	0.2	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.3	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.3	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1	4.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	1.3	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	0.3	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1	1.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	1.3	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	5.3	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	1.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099) L-cystine transmembrane transporter activity(GO:0015184)
0.1	12.7	GO:0005096	GTPase activator activity(GO:0005096)
0.1	0.3	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.6	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	1.6	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.9	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.9	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	2.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	2.1	GO:0005518	collagen binding(GO:0005518)
0.0	0.5	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0050733	RS domain binding(GO:0050733)
0.0	0.7	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.7	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.5	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.5	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.7	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.5	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.6	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	1.5	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	1.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.6	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	1.4	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.0	0.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	1.0	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	1.0	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	16.8	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	38.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.5	18.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4	4.9	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.4	22.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.3	2.5	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.3	5.7	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	6.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	6.8	ST GAQ PATHWAY	G alpha q Pathway
0.2	9.8	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	9.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.2	4.8	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	7.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	8.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	9.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	13.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	6.6	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2	28.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	1.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	4.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	7.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	5.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	8.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	2.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	2.9	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	0.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	11.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	6.8	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	6.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	5.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	3.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	5.7	PID BMP PATHWAY	BMP receptor signaling
0.1	6.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	0.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	1.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	21.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.5	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	1.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	0.6	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	1.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	2.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	3.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.5	PID MYC PATHWAY	C-MYC pathway
0.0	0.5	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	9.3	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	0.9	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.4	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	2.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	72.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.3	13.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.7	4.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.7	58.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6	11.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	18.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.6	9.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.6	5.7	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.5	3.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.5	5.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.4	6.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	4.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.4	3.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.4	14.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.4	4.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.3	14.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.3	7.7	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.3	7.9	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	5.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.3	4.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	5.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	3.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.3	12.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.3	3.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	3.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	8.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2	4.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	4.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	1.6	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.2	1.8	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	12.6	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.2	2.7	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2	1.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	14.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	6.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	3.6	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.2	19.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	10.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	4.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	6.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.2	3.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	8.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	2.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.4	REACTOME OPSINS	Genes involved in Opsins
0.1	2.0	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	10.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.8	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	3.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	6.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	9.4	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.1	4.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	3.9	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	0.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	4.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	7.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	1.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	6.9	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	1.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	3.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	3.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	2.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	2.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	5.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	4.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	2.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.9	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.6	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis

Results for MAFK

Z-value: 4.89

Motif logo

Transcription factors associated with MAFK

Activity-expression correlation:

Activity profile of MAFK motif

Sorted Z-values of MAFK motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFK

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: