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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MBD2

Z-value: 0.28

Motif logo

Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
ENSG00000134046.12 MBD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg38_v1_chr18_-_54224578_54224689-0.101.5e-01Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_52948840 6.44 ENST00000388837.6
ENST00000550600.5
keratin 18
chr11_-_2139382 6.29 ENST00000416167.7
insulin like growth factor 2
chr17_-_28951285 5.86 ENST00000577226.5
PHD finger protein 12
chr3_-_185824966 5.74 ENST00000457616.6
ENST00000346192.7
insulin like growth factor 2 mRNA binding protein 2
chr13_+_98143084 5.72 ENST00000319562.11
ENST00000627049.2
FERM, ARH/RhoGEF and pleckstrin domain protein 1
chr5_+_176238365 5.53 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SUMO interacting motifs containing 1
chr14_+_77320996 5.48 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
glutathione S-transferase zeta 1
chr3_-_185825029 5.46 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chr3_+_14947680 5.16 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr11_-_75525925 5.02 ENST00000336898.8
glycerophosphodiester phosphodiesterase domain containing 5
chr11_+_45146631 4.92 ENST00000534751.3
ENST00000683152.1
PR/SET domain 11
chr3_+_71753834 4.74 ENST00000304411.3
G protein-coupled receptor 27
chr2_+_112275588 4.70 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr20_-_31723491 4.66 ENST00000676582.1
ENST00000422920.2
BCL2 like 1
chr17_-_64919456 4.64 ENST00000339474.9
ENST00000584306.6
ENST00000581368.5
leucine rich repeat containing 37 member A3
chr14_-_93333015 4.61 ENST00000334746.10
ENST00000554565.5
ENST00000298896.7
BTB domain containing 7
chr2_-_219060914 4.58 ENST00000295731.7
Indian hedgehog signaling molecule
chr2_-_38377256 4.41 ENST00000443098.5
ENST00000449130.5
ENST00000651368.1
ENST00000378954.9
ENST00000419554.6
ENST00000451483.1
ENST00000406122.5
atlastin GTPase 2
chr18_+_74597850 4.39 ENST00000582337.5
ENST00000299687.10
zinc finger protein 407
chr11_-_62601223 4.18 ENST00000527204.5
metastasis associated 1 family member 2
chr13_+_73058993 4.12 ENST00000377687.6
Kruppel like factor 5
chr2_+_73984902 4.05 ENST00000409262.8
tet methylcytosine dioxygenase 3
chr10_-_90857983 4.00 ENST00000336152.8
5-hydroxytryptamine receptor 7
chr8_+_30384511 4.00 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RNA binding protein, mRNA processing factor
chr20_-_31723902 3.92 ENST00000676942.1
ENST00000450273.2
ENST00000678563.1
ENST00000456404.6
ENST00000420488.6
ENST00000439267.2
BCL2 like 1
chr3_+_14947568 3.70 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr11_+_65084257 3.64 ENST00000526791.1
ENST00000526945.5
zinc finger protein like 1
chr3_+_141402322 3.62 ENST00000510338.5
ENST00000504673.5
zinc finger and BTB domain containing 38
chr5_-_180649579 3.60 ENST00000261937.11
ENST00000502649.5
fms related receptor tyrosine kinase 4
chr14_-_77320855 3.58 ENST00000556394.2
ENST00000261534.9
protein O-mannosyltransferase 2
chr17_-_181640 3.56 ENST00000613549.3
double C2 domain beta
chr11_-_119729158 3.55 ENST00000264025.8
nectin cell adhesion molecule 1
chr2_+_216633411 3.54 ENST00000233809.9
insulin like growth factor binding protein 2
chr19_+_36054879 3.50 ENST00000378860.8
ENST00000427823.3
ENST00000681542.1
ENST00000680321.1
ENST00000680359.1
ENST00000680403.1
ENST00000679714.1
ENST00000679682.1
ENST00000401500.7
ENST00000680564.1
WD repeat domain 62
chr20_+_64080074 3.46 ENST00000336866.7
opioid related nociceptin receptor 1
chr10_-_11611754 3.39 ENST00000609104.5
USP6 N-terminal like
chr1_+_52142044 3.38 ENST00000287727.8
ENST00000371591.2
zinc finger FYVE-type containing 9
chr8_+_38901218 3.36 ENST00000521746.5
ENST00000616927.4
pleckstrin homology domain containing A2
chr9_-_124771238 3.35 ENST00000344523.8
ENST00000373584.7
nuclear receptor subfamily 6 group A member 1
chr20_+_58692767 3.32 ENST00000356091.11
aminopeptidase like 1
chr8_-_144462848 3.30 ENST00000530374.6
cysteine and histidine rich 1
chr2_+_147844601 3.23 ENST00000404590.1
activin A receptor type 2A
chr19_-_11262499 3.20 ENST00000294618.12
dedicator of cytokinesis 6
chr3_+_46883337 3.16 ENST00000313049.9
parathyroid hormone 1 receptor
chr1_+_225810057 3.14 ENST00000272167.10
ENST00000448202.5
epoxide hydrolase 1
chr11_+_65084194 3.13 ENST00000294258.8
ENST00000525509.1
ENST00000526334.5
zinc finger protein like 1
chr8_-_56211257 3.11 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr8_+_80486209 3.09 ENST00000426744.5
ENST00000455036.8
zinc finger and BTB domain containing 10
chr14_-_77320813 3.07 ENST00000682467.1
protein O-mannosyltransferase 2
chr12_-_47819866 3.04 ENST00000354334.7
ENST00000430670.5
ENST00000552960.5
ENST00000440293.5
ENST00000080059.12
histone deacetylase 7
chr11_-_62601818 3.03 ENST00000278823.7
metastasis associated 1 family member 2
chr9_-_124771304 3.03 ENST00000416460.6
ENST00000487099.7
nuclear receptor subfamily 6 group A member 1
chr22_-_31346143 3.03 ENST00000405309.7
ENST00000351933.8
POZ/BTB and AT hook containing zinc finger 1
chr8_-_22131003 3.02 ENST00000381418.9
HR lysine demethylase and nuclear receptor corepressor
chr19_+_36054930 3.00 ENST00000679757.1
ENST00000270301.12
WD repeat domain 62
chr2_+_48314637 2.99 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr1_+_27726005 2.96 ENST00000530324.5
ENST00000234549.11
ENST00000373949.5
ENST00000010299.10
family with sequence similarity 76 member A
chrX_-_74614612 2.94 ENST00000349225.2
ENST00000332687.11
ring finger protein, LIM domain interacting
chr19_+_35717973 2.92 ENST00000673918.1
ENST00000420124.4
lysine methyltransferase 2B
chr12_-_54588636 2.92 ENST00000257905.13
protein phosphatase 1 regulatory inhibitor subunit 1A
chr11_+_69641146 2.91 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr2_+_109794263 2.90 ENST00000272454.10
RANBP2 like and GRIP domain containing 5
chr1_+_27725945 2.87 ENST00000373954.11
ENST00000419687.6
family with sequence similarity 76 member A
chr3_-_38029604 2.86 ENST00000334661.5
phospholipase C delta 1
chr12_-_116881431 2.81 ENST00000257572.5
harakiri, BCL2 interacting protein
chr10_-_77926724 2.80 ENST00000372391.7
discs large MAGUK scaffold protein 5
chr14_-_77320741 2.78 ENST00000682795.1
ENST00000682247.1
protein O-mannosyltransferase 2
chrX_-_53321319 2.77 ENST00000640694.1
ENST00000674510.1
ENST00000675719.1
ENST00000642864.1
IQ motif and Sec7 domain ArfGEF 2
chr17_+_19648792 2.74 ENST00000630662.2
aldehyde dehydrogenase 3 family member A2
chr12_-_42238261 2.71 ENST00000380790.4
YY1 associated factor 2
chr12_-_42238203 2.69 ENST00000327791.8
ENST00000534854.7
YY1 associated factor 2
chr9_+_129665603 2.69 ENST00000372469.6
paired related homeobox 2
chr17_+_66964638 2.67 ENST00000262138.4
calcium voltage-gated channel auxiliary subunit gamma 4
chr3_+_101849505 2.67 ENST00000326151.9
ENST00000326172.9
NFKB inhibitor zeta
chr1_-_48472007 2.64 ENST00000371843.7
spermatogenesis associated 6
chr19_+_46860972 2.62 ENST00000672722.1
Rho GTPase activating protein 35
chr17_+_50561010 2.59 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
calcium voltage-gated channel subunit alpha1 G
chr4_-_121952014 2.59 ENST00000379645.8
transient receptor potential cation channel subfamily C member 3
chr1_+_81800906 2.56 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr22_-_31346317 2.55 ENST00000266269.10
POZ/BTB and AT hook containing zinc finger 1
chr6_+_2765361 2.55 ENST00000380773.9
ENST00000380771.8
ENST00000618555.4
WRN helicase interacting protein 1
chr5_-_179806830 2.53 ENST00000292591.12
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
chr17_+_19648915 2.52 ENST00000672567.1
ENST00000672709.1
aldehyde dehydrogenase 3 family member A2
chr17_+_19648723 2.52 ENST00000672357.1
ENST00000584332.6
ENST00000176643.11
ENST00000339618.8
ENST00000579855.5
ENST00000671878.1
ENST00000395575.7
aldehyde dehydrogenase 3 family member A2
chr14_-_21098570 2.50 ENST00000360947.8
zinc finger protein 219
chr19_+_589873 2.48 ENST00000251287.3
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr3_-_98901656 2.47 ENST00000326840.11
discoidin, CUB and LCCL domain containing 2
chr19_-_45973863 2.45 ENST00000263257.6
NOVA alternative splicing regulator 2
chr17_+_50560703 2.44 ENST00000359106.10
calcium voltage-gated channel subunit alpha1 G
chr12_-_54588516 2.43 ENST00000547431.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr8_-_118111806 2.42 ENST00000378204.7
exostosin glycosyltransferase 1
chr17_+_18039370 2.38 ENST00000268719.9
ENST00000376345.3
GID complex subunit 4 homolog
chr7_-_519239 2.37 ENST00000354513.9
ENST00000402802.7
platelet derived growth factor subunit A
chr20_+_64080129 2.35 ENST00000355631.8
opioid related nociceptin receptor 1
chr2_+_26692686 2.34 ENST00000620977.1
ENST00000302909.4
potassium two pore domain channel subfamily K member 3
chr4_+_38664189 2.31 ENST00000514033.1
ENST00000261438.10
Kruppel like factor 3
chr12_+_57089094 2.30 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chr14_+_73950489 2.28 ENST00000554320.1
coenzyme Q6, monooxygenase
chr3_-_134250831 2.28 ENST00000623711.4
receptor like tyrosine kinase
chr6_+_125154189 2.28 ENST00000532429.5
ENST00000534199.5
TPD52 like 1
chr9_-_109498251 2.27 ENST00000374541.4
ENST00000262539.7
protein tyrosine phosphatase non-receptor type 3
chr7_+_129611680 2.27 ENST00000393232.6
ENST00000454688.5
ENST00000223190.8
ENST00000311967.6
nuclear respiratory factor 1
chr6_-_10412367 2.26 ENST00000379608.9
transcription factor AP-2 alpha
chr14_-_88554898 2.26 ENST00000556564.6
protein tyrosine phosphatase non-receptor type 21
chr10_-_121598396 2.25 ENST00000336553.10
ENST00000457416.6
fibroblast growth factor receptor 2
chr6_-_10414985 2.25 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr9_+_137205662 2.25 ENST00000371521.8
ENST00000684003.1
ENST00000427047.6
ENST00000458322.2
NADPH dependent diflavin oxidoreductase 1
chr3_+_184561768 2.24 ENST00000330394.3
EPH receptor B3
chr10_-_90857680 2.23 ENST00000277874.10
ENST00000371719.2
5-hydroxytryptamine receptor 7
chr9_+_134326435 2.23 ENST00000481739.2
retinoid X receptor alpha
chr15_+_100602519 2.22 ENST00000332783.12
ENST00000558747.5
ENST00000343276.4
ankyrin repeat and SOCS box containing 7
chr8_+_80485641 2.21 ENST00000430430.5
zinc finger and BTB domain containing 10
chr11_-_89491320 2.21 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr19_+_8209300 2.19 ENST00000558268.5
ENST00000558331.5
ceramide synthase 4
chr19_+_3359563 2.17 ENST00000589123.5
ENST00000395111.7
ENST00000586919.5
nuclear factor I C
chr9_-_127854636 2.17 ENST00000344849.4
ENST00000373203.9
endoglin
chrX_+_69504320 2.17 ENST00000252338.5
family with sequence similarity 155 member B
chr11_-_76670737 2.17 ENST00000260061.9
ENST00000404995.5
leucine rich repeat containing 32
chr7_-_135510074 2.16 ENST00000428680.6
ENST00000423368.6
ENST00000451834.5
ENST00000361528.8
ENST00000541284.5
ENST00000315544.6
CCR4-NOT transcription complex subunit 4
chr14_+_70907661 2.16 ENST00000439984.7
pecanex 1
chr19_+_5805018 2.14 ENST00000303212.3
neurturin
chr16_-_49281819 2.14 ENST00000219197.11
cerebellin 1 precursor
chr12_-_114684151 2.13 ENST00000349155.7
T-box transcription factor 3
chr20_-_610299 2.12 ENST00000246080.4
transcription factor 15
chr10_-_103855406 2.10 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chr22_-_20016807 2.09 ENST00000263207.8
ARVCF delta catenin family member
chr10_+_96832252 2.09 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr20_-_62065834 2.07 ENST00000252996.9
TATA-box binding protein associated factor 4
chr7_+_43112593 2.07 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr19_-_10231293 2.05 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr14_-_103057509 2.04 ENST00000361246.7
CDC42 binding protein kinase beta
chr2_+_238426920 2.02 ENST00000264607.9
ankyrin repeat and SOCS box containing 1
chr19_+_35268921 2.02 ENST00000222305.8
ENST00000343550.9
upstream transcription factor 2, c-fos interacting
chr12_+_119989869 2.01 ENST00000397558.6
BICD family like cargo adaptor 1
chr6_-_46015812 2.00 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chr6_-_93419545 2.00 ENST00000369297.1
ENST00000369303.9
ENST00000680224.1
ENST00000681532.1
ENST00000679565.1
EPH receptor A7
chr1_-_48472166 1.99 ENST00000371847.8
ENST00000396199.7
spermatogenesis associated 6
chrX_+_44873552 1.99 ENST00000683021.1
lysine demethylase 6A
chr5_+_128083757 1.97 ENST00000262461.7
ENST00000628403.2
ENST00000343225.4
solute carrier family 12 member 2
chr17_-_48613468 1.97 ENST00000498634.2
homeobox B8
chr11_-_86955385 1.96 ENST00000531380.2
frizzled class receptor 4
chr17_-_13601901 1.94 ENST00000284110.2
heparan sulfate-glucosamine 3-sulfotransferase 3A1
chr7_-_17940468 1.94 ENST00000611725.4
ENST00000409604.1
ENST00000428135.7
sorting nexin 13
chr1_+_156114251 1.94 ENST00000361308.9
lamin A/C
chr14_-_99604167 1.94 ENST00000380243.9
coiled-coil domain containing 85C
chr9_+_34989641 1.93 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr20_-_49915509 1.93 ENST00000289431.10
spermatogenesis associated 2
chr20_-_17682060 1.91 ENST00000455029.3
ribosome binding protein 1
chrX_-_17860707 1.91 ENST00000360011.5
retinoic acid induced 2
chrX_+_153687918 1.91 ENST00000253122.10
solute carrier family 6 member 8
chr5_-_180649613 1.90 ENST00000393347.7
ENST00000619105.4
fms related receptor tyrosine kinase 4
chr4_+_1793776 1.90 ENST00000352904.6
fibroblast growth factor receptor 3
chr8_-_31033294 1.89 ENST00000523392.2
purine rich element binding protein G
chr16_+_1972035 1.88 ENST00000568546.6
ENST00000615855.4
transducin beta like 3
chr10_-_121598234 1.87 ENST00000369058.7
ENST00000369060.8
ENST00000359354.6
fibroblast growth factor receptor 2
chr12_-_114683590 1.85 ENST00000257566.7
T-box transcription factor 3
chr22_+_19714450 1.84 ENST00000455784.7
ENST00000406395.5
septin 5
chr1_+_156114700 1.83 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chr19_+_6739650 1.83 ENST00000313285.12
ENST00000313244.14
ENST00000596758.5
thyroid hormone receptor interactor 10
chr12_-_57006476 1.81 ENST00000300101.3
zinc finger and BTB domain containing 39
chr17_+_31094969 1.80 ENST00000431387.8
ENST00000358273.9
neurofibromin 1
chr1_-_156282799 1.80 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr12_+_67648737 1.80 ENST00000344096.4
ENST00000393555.3
dual specificity tyrosine phosphorylation regulated kinase 2
chr19_+_8209320 1.79 ENST00000561053.5
ENST00000559450.5
ENST00000251363.10
ENST00000559336.5
ceramide synthase 4
chr17_+_50056095 1.79 ENST00000320031.13
integrin subunit alpha 3
chr16_+_22814154 1.77 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr15_+_92393841 1.76 ENST00000268164.8
ENST00000539113.5
ENST00000555434.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr3_-_134250744 1.76 ENST00000620660.4
receptor like tyrosine kinase
chr3_+_170357647 1.75 ENST00000476188.5
ENST00000259119.9
ENST00000426052.6
SKI like proto-oncogene
chr12_-_49060742 1.75 ENST00000301067.12
ENST00000683543.1
lysine methyltransferase 2D
chr8_+_38901327 1.75 ENST00000519640.5
ENST00000617275.5
pleckstrin homology domain containing A2
chr16_+_1153202 1.74 ENST00000358590.8
ENST00000638323.1
calcium voltage-gated channel subunit alpha1 H
chr2_-_218671975 1.73 ENST00000295704.7
ring finger protein 25
chr14_+_70907450 1.72 ENST00000304743.7
pecanex 1
chr18_-_812516 1.72 ENST00000584307.5
YES proto-oncogene 1, Src family tyrosine kinase
chr19_-_19628197 1.72 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr6_+_167826848 1.71 ENST00000683244.1
ENST00000400825.8
afadin, adherens junction formation factor
chr11_-_59615673 1.71 ENST00000263847.6
oxysterol binding protein
chr17_+_75525682 1.71 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr16_+_58025745 1.71 ENST00000219271.4
matrix metallopeptidase 15
chr3_-_53046031 1.70 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr11_-_6655788 1.70 ENST00000299441.5
dachsous cadherin-related 1
chr1_+_81800368 1.70 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr17_-_979726 1.70 ENST00000336868.8
nucleoredoxin
chr16_-_30894264 1.69 ENST00000380317.8
BAF chromatin remodeling complex subunit BCL7C
chr2_+_147845020 1.66 ENST00000241416.12
activin A receptor type 2A
chr19_-_49119092 1.65 ENST00000408991.4
chromosome 19 open reading frame 73
chr22_+_26169454 1.64 ENST00000248933.11
seizure related 6 homolog like
chr10_+_115093331 1.63 ENST00000609571.5
ENST00000355044.8
ENST00000526946.5
attractin like 1
chr11_+_2444986 1.63 ENST00000155840.12
potassium voltage-gated channel subfamily Q member 1
chr4_-_11428868 1.63 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr11_-_89491131 1.62 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr19_-_17245889 1.62 ENST00000291442.4
nuclear receptor subfamily 2 group F member 6
chr15_-_45187955 1.61 ENST00000560471.5
ENST00000560540.5
Src homology 2 domain containing F
chr1_+_185045515 1.61 ENST00000367509.8
ENST00000367510.8
ring finger protein 2
chr10_+_114043858 1.60 ENST00000369295.4
adrenoceptor beta 1
chr1_+_156369202 1.60 ENST00000537040.6
Rh family B glycoprotein
chr16_+_1153098 1.58 ENST00000348261.11
calcium voltage-gated channel subunit alpha1 H
chr6_-_10415043 1.58 ENST00000379613.10
transcription factor AP-2 alpha
chr8_+_142449430 1.57 ENST00000643448.1
ENST00000517894.5
adhesion G protein-coupled receptor B1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.5 4.6 GO:0048073 regulation of eye pigmentation(GO:0048073)
1.5 6.1 GO:0003409 optic cup structural organization(GO:0003409)
1.3 9.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.3 4.0 GO:0060596 mammary placode formation(GO:0060596) His-Purkinje system cell differentiation(GO:0060932)
1.2 6.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
1.2 8.6 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
1.2 3.6 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.2 5.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.1 6.8 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
1.0 4.0 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.9 4.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.9 3.6 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.8 1.6 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.8 2.4 GO:0071072 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.8 6.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.8 3.9 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.8 2.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.7 2.2 GO:0036245 cellular response to menadione(GO:0036245)
0.7 5.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.7 2.2 GO:0060528 regulation of translational initiation by iron(GO:0006447) secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.7 2.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.7 4.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.7 5.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.7 1.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.7 2.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 3.8 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.6 6.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.6 6.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.6 1.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.5 6.5 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.5 2.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.5 2.6 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.5 1.5 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.5 4.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.5 2.1 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5 2.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.5 1.5 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.5 3.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 2.6 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.4 2.6 GO:0035617 stress granule disassembly(GO:0035617)
0.4 1.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.4 2.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.4 1.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4 1.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.4 5.0 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.4 3.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 2.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 1.7 GO:0001555 oocyte growth(GO:0001555)
0.3 4.8 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.3 3.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 1.0 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.3 3.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.3 2.3 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.3 2.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 2.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.3 1.8 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532)
0.3 1.5 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 2.9 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 1.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 2.3 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.3 1.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.3 1.1 GO:1904021 regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.3 1.4 GO:0090269 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.3 5.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 3.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.3 0.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 1.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 1.3 GO:0072093 metanephric renal vesicle formation(GO:0072093)
0.3 1.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 1.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 2.9 GO:0070141 response to UV-A(GO:0070141)
0.2 2.7 GO:0060174 limb bud formation(GO:0060174)
0.2 6.4 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.2 2.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 2.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 0.9 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 2.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 6.7 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.2 4.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.2 4.5 GO:0010226 response to lithium ion(GO:0010226)
0.2 1.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.0 GO:0032902 nerve growth factor production(GO:0032902)
0.2 3.1 GO:0060736 positive regulation of glial cell proliferation(GO:0060252) prostate gland growth(GO:0060736)
0.2 0.8 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 0.4 GO:0060437 lung growth(GO:0060437)
0.2 2.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 8.7 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.2 2.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.2 2.0 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.2 0.9 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 2.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 0.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 7.1 GO:0098534 centriole assembly(GO:0098534)
0.2 1.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 0.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 2.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 2.4 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 2.2 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.2 3.7 GO:0090494 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.2 3.6 GO:0098915 potassium ion export across plasma membrane(GO:0097623) membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.2 0.9 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.2 2.9 GO:0001502 cartilage condensation(GO:0001502)
0.2 2.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.3 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 1.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 2.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 3.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 1.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 1.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.9 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 3.8 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 3.0 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.0 GO:0030539 male genitalia development(GO:0030539)
0.1 2.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 2.8 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.7 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 1.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.3 GO:0031550 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 2.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 2.2 GO:0022038 corpus callosum development(GO:0022038)
0.1 1.5 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 1.6 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 1.4 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 3.3 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.1 0.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 11.2 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.1 2.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.9 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.9 GO:0021511 spinal cord patterning(GO:0021511)
0.1 6.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 4.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 3.2 GO:0060074 synapse maturation(GO:0060074)
0.1 0.1 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 2.0 GO:0007625 grooming behavior(GO:0007625)
0.1 0.1 GO:0032687 regulation of interleukin-3 production(GO:0032672) negative regulation of interferon-alpha production(GO:0032687)
0.1 0.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 6.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.2 GO:0051775 response to redox state(GO:0051775)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 3.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.6 GO:0015886 heme transport(GO:0015886)
0.1 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.1 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.9 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.8 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1 1.4 GO:0044804 nucleophagy(GO:0044804)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.0 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 2.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 2.0 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.9 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 2.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 2.1 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 12.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 3.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 2.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine modification(GO:0002949) tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 3.6 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 1.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.6 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 2.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 1.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.8 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 1.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.9 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 2.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.8 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 1.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 3.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0 1.0 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 1.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 1.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 3.1 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.0 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.2 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.3 GO:0044782 cilium organization(GO:0044782)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0097224 sperm connecting piece(GO:0097224)
0.8 4.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.7 8.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.7 2.2 GO:0072563 endothelial microparticle(GO:0072563)
0.7 4.0 GO:0001940 male pronucleus(GO:0001940)
0.6 3.5 GO:0032584 growth cone membrane(GO:0032584)
0.5 5.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 1.8 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.4 1.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 9.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 3.8 GO:0005638 lamin filament(GO:0005638)
0.3 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 5.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 5.9 GO:0016580 Sin3 complex(GO:0016580)
0.3 3.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 1.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 4.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 4.0 GO:0005685 U1 snRNP(GO:0005685)
0.2 6.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 14.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.6 GO:0001739 sex chromatin(GO:0001739)
0.2 6.4 GO:0034451 centriolar satellite(GO:0034451)
0.2 0.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.0 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.6 GO:0001741 XY body(GO:0001741)
0.1 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 3.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 3.3 GO:0071565 nBAF complex(GO:0071565)
0.1 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.9 GO:0032797 SMN complex(GO:0032797)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 6.4 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 4.1 GO:0031201 SNARE complex(GO:0031201)
0.1 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.7 GO:0005921 gap junction(GO:0005921)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 6.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 8.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 3.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 7.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 2.1 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 3.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.2 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 2.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 5.4 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 2.0 GO:0042641 actomyosin(GO:0042641)
0.0 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 43.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 3.3 GO:0001650 fibrillar center(GO:0001650)
0.0 3.6 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0070160 occluding junction(GO:0070160)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 8.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0044450 microtubule organizing center part(GO:0044450)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
1.7 5.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.5 5.8 GO:0001626 nociceptin receptor activity(GO:0001626)
1.4 5.5 GO:0032184 SUMO polymer binding(GO:0032184)
1.3 9.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.3 5.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.1 3.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.1 4.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
1.0 5.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.9 3.7 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.8 9.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.8 2.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.8 4.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.7 8.9 GO:0051434 BH3 domain binding(GO:0051434)
0.7 2.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.7 5.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 2.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.6 3.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.6 4.9 GO:0098821 BMP receptor activity(GO:0098821)
0.6 7.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 4.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.6 4.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 2.2 GO:0070644 9-cis retinoic acid receptor activity(GO:0004886) vitamin D response element binding(GO:0070644)
0.5 3.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.5 1.6 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.5 3.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.5 6.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.5 3.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 2.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 4.6 GO:0032027 myosin light chain binding(GO:0032027)
0.4 2.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 3.0 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.4 5.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 5.2 GO:0005113 patched binding(GO:0005113)
0.4 3.5 GO:0004969 histamine receptor activity(GO:0004969)
0.4 1.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.4 1.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.4 2.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.4 GO:0035276 ethanol binding(GO:0035276)
0.3 9.2 GO:0001968 fibronectin binding(GO:0001968)
0.3 3.7 GO:0036122 BMP binding(GO:0036122)
0.3 3.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 0.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 2.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 2.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 2.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.3 12.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 1.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 0.8 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3 1.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 2.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 4.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 3.5 GO:0046790 virion binding(GO:0046790)
0.3 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 2.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 2.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 1.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 1.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.6 GO:0098808 mRNA cap binding(GO:0098808)
0.2 3.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 5.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 2.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 5.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 1.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.5 GO:0045545 syndecan binding(GO:0045545)
0.2 4.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 3.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 7.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 5.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 16.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.6 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804) L-phenylalanine aminotransferase activity(GO:0070546)
0.1 1.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 2.0 GO:0034452 dynactin binding(GO:0034452)
0.1 0.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.3 GO:0043199 sulfate binding(GO:0043199)
0.1 1.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.9 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.1 5.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 4.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 5.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 4.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 5.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 3.3 GO:0008235 aminopeptidase activity(GO:0004177) metalloexopeptidase activity(GO:0008235)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0003696 satellite DNA binding(GO:0003696)
0.1 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 11.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 2.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 2.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 3.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 18.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 9.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 1.3 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 6.1 GO:0008083 growth factor activity(GO:0008083)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 4.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.1 GO:0051087 chaperone binding(GO:0051087)
0.0 7.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 2.2 GO:0008168 methyltransferase activity(GO:0008168)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 8.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 6.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 3.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 9.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 5.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 7.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 10.6 PID FGF PATHWAY FGF signaling pathway
0.1 0.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 8.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 11.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 7.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 5.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 4.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 4.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 4.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 ST GA13 PATHWAY G alpha 13 Pathway
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 4.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 2.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.5 8.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 6.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 2.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 9.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 2.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 6.6 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 7.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 17.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 7.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 7.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 5.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 2.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 11.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 6.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 10.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 4.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 2.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.5 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 9.2 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.1 REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX Genes involved in Signaling by TGF-beta Receptor Complex
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.0 REACTOME TRANSLATION Genes involved in Translation
0.0 1.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex