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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MECOM

Z-value: 7.39

Motif logo

Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
ENSG00000085276.19 MECOM

Activity-expression correlation:

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_87529092 37.14 ENST00000503414.5
SPARC like 1
chr11_-_5227063 34.61 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr17_-_68955332 26.64 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr12_-_14885845 20.71 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr11_+_60378524 18.70 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr11_+_60378475 18.43 ENST00000358246.5
membrane spanning 4-domains A7
chrX_-_19965142 18.19 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr10_+_104275126 17.24 ENST00000369707.2
glutathione S-transferase omega 2
chr19_-_20661507 13.35 ENST00000612591.4
ENST00000595405.1
zinc finger protein 626
chr19_-_20661563 13.19 ENST00000601440.6
ENST00000291750.6
ENST00000595094.1
zinc finger protein 626
novel transcript
chr11_-_18634332 12.82 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr6_-_52995170 12.36 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr10_-_86957582 11.79 ENST00000372027.10
multimerin 2
chr8_-_27258414 11.58 ENST00000523048.5
stathmin 4
chr14_-_24114913 10.51 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr8_-_38150943 10.47 ENST00000276449.9
steroidogenic acute regulatory protein
chr17_-_39152571 10.46 ENST00000415163.5
ENST00000441877.5
ENST00000444911.6
plexin domain containing 1
chr9_+_127611760 10.14 ENST00000625363.2
ENST00000626539.3
syntaxin binding protein 1
chrX_-_43882411 9.80 ENST00000378069.5
monoamine oxidase B
chr2_+_188974364 9.77 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr8_-_39838201 9.68 ENST00000347580.8
ENST00000379853.6
ENST00000265708.9
ENST00000521880.5
ADAM metallopeptidase domain 2
chr8_-_27258386 9.52 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr22_+_28742024 9.48 ENST00000216027.8
ENST00000398941.6
HscB mitochondrial iron-sulfur cluster cochaperone
chr5_-_65624288 9.38 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chr3_-_45842066 9.16 ENST00000445698.1
ENST00000296135.11
leucine zipper transcription factor like 1
chr16_+_19285724 9.04 ENST00000636231.2
ENST00000493231.5
ENST00000465414.1
C-type lectin domain containing 19A
chr8_-_39838250 9.03 ENST00000622267.1
ADAM metallopeptidase domain 2
chr5_+_75512058 9.03 ENST00000514296.5
DNA polymerase kappa
chr12_+_55362975 9.01 ENST00000641576.1
olfactory receptor family 6 subfamily C member 75
chr17_-_3104422 9.01 ENST00000641064.1
ENST00000641833.1
olfactory receptor family 1 subfamily D member 2
chr14_+_24114627 8.69 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr2_-_236507515 8.67 ENST00000309507.9
IQ motif containing with AAA domain 1
chr17_+_55267584 8.63 ENST00000575345.5
HLF transcription factor, PAR bZIP family member
chr7_-_101200912 8.51 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr2_-_236507428 8.45 ENST00000409907.8
IQ motif containing with AAA domain 1
chr7_+_97732046 8.42 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chr2_-_223602284 7.78 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr9_+_79571767 7.73 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr6_+_69232406 7.58 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr1_+_103749898 7.43 ENST00000622339.5
amylase alpha 1C
chr6_+_31547560 7.36 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr4_+_73409340 7.16 ENST00000511370.1
albumin
chr10_-_99235783 7.14 ENST00000370546.5
ENST00000614306.1
heparanase 2 (inactive)
chr19_+_49527988 7.10 ENST00000270645.8
reticulocalbin 3
chr4_-_76023489 6.95 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr17_-_45060988 6.94 ENST00000342350.9
dephospho-CoA kinase domain containing
chr3_+_147409357 6.93 ENST00000282928.5
Zic family member 1
chr6_+_44342639 6.81 ENST00000674044.1
ENST00000515220.5
ENST00000323108.12
spermatogenesis associated serine rich 1
chr16_+_56191476 6.80 ENST00000262493.12
G protein subunit alpha o1
chr6_+_152697934 6.61 ENST00000532295.1
MYC target 1
chr12_+_71686061 6.57 ENST00000266673.10
ENST00000550524.5
transmembrane protein 19
chr11_+_17351786 6.48 ENST00000338965.9
natural killer cell cytotoxicity receptor 3 ligand 1
chr9_+_79571956 6.43 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr19_+_22052430 6.40 ENST00000651332.1
ENST00000594363.5
ENST00000597927.1
ENST00000594947.6
zinc finger protein 257
chr14_+_19743571 6.14 ENST00000642117.2
olfactory receptor family 4 subfamily Q member 3
chr6_-_87095059 6.05 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr6_-_154510675 6.03 ENST00000607772.6
CNKSR family member 3
chr10_+_55599041 5.91 ENST00000512524.4
MT-RNR2 like 5
chr10_-_99235846 5.78 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chr1_-_206117386 5.54 ENST00000367126.5
arginine vasopressin receptor 1B
chr15_-_78811415 5.52 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr15_+_42274185 5.50 ENST00000440615.6
ENST00000318010.12
glucosidase alpha, neutral C
chrX_-_86047527 5.33 ENST00000615443.1
ENST00000357749.7
CHM Rab escort protein
chrX_-_102439932 5.30 ENST00000602195.5
nuclear RNA export factor 2B
chr7_-_15561986 5.23 ENST00000342526.8
alkylglycerol monooxygenase
chr7_+_17298642 5.23 ENST00000242057.9
aryl hydrocarbon receptor
chr5_+_55024250 5.13 ENST00000231009.3
granzyme K
chr2_-_144517663 5.07 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr5_+_65624998 4.98 ENST00000399438.8
ENST00000438419.6
ENST00000231526.8
ENST00000505553.5
ENST00000510585.3
trafficking protein particle complex 13
shieldin complex subunit 3
chr7_+_49773632 4.97 ENST00000340652.5
von Willebrand factor C domain containing 2
chr14_-_24081928 4.88 ENST00000396995.1
neural retina leucine zipper
chr7_-_120858066 4.87 ENST00000222747.8
tetraspanin 12
chr4_+_95091462 4.79 ENST00000264568.8
bone morphogenetic protein receptor type 1B
chr5_+_140786136 4.79 ENST00000378133.4
ENST00000504120.4
protocadherin alpha 1
chr9_+_131502789 4.66 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr12_+_12049855 4.56 ENST00000586576.5
ENST00000464885.6
BCL2 like 14
chr3_-_197260722 4.53 ENST00000654733.1
ENST00000661808.1
discs large MAGUK scaffold protein 1
chrX_+_102247167 4.49 ENST00000625106.4
nuclear RNA export factor 2
chr15_+_70892809 4.49 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chrX_-_63755032 4.49 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr5_-_161546671 4.49 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr14_+_21990357 4.38 ENST00000390444.1
T cell receptor alpha variable 16
chr11_+_5383812 4.30 ENST00000642046.1
olfactory receptor family 51 subfamily M member 1
chr7_+_20615653 4.26 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr11_+_61241175 4.16 ENST00000312403.10
pepsinogen A5
chrY_+_25622162 4.13 ENST00000361963.3
ENST00000306609.4
chromodomain Y-linked 1
chr6_+_29657120 4.12 ENST00000396704.7
ENST00000416766.6
ENST00000483013.5
ENST00000490427.5
ENST00000376891.8
ENST00000376898.7
ENST00000396701.6
ENST00000494692.5
ENST00000431798.6
myelin oligodendrocyte glycoprotein
chr14_-_24081986 4.08 ENST00000560550.1
neural retina leucine zipper
chr22_+_35717872 4.06 ENST00000249044.2
apolipoprotein L5
chr1_+_103750406 4.02 ENST00000370079.3
amylase alpha 1C
chrX_+_15507302 3.97 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr12_+_20695553 3.92 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr12_+_18242955 3.91 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chrY_+_18025787 3.85 ENST00000250838.6
chromodomain Y-linked 2A
chr14_-_68794597 3.84 ENST00000336440.3
ZFP36 ring finger protein like 1
chr8_+_39902275 3.75 ENST00000518804.5
ENST00000519154.5
ENST00000522495.5
ENST00000522840.1
indoleamine 2,3-dioxygenase 1
chr1_+_209686173 3.74 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr7_-_8262533 3.72 ENST00000447326.5
ENST00000406470.6
ENST00000407906.5
islet cell autoantigen 1
chr19_-_45863130 3.69 ENST00000599460.5
ENST00000245934.12
ENST00000598059.5
symplekin
chr8_+_109362453 3.66 ENST00000378402.10
PKHD1 like 1
chr9_+_33240159 3.62 ENST00000379721.4
serine peptidase inhibitor Kazal type 4
chr3_+_4303304 3.56 ENST00000358065.4
SET domain and mariner transposase fusion gene
chr6_+_152697888 3.53 ENST00000367245.5
ENST00000529453.1
MYC target 1
chr12_+_20695323 3.51 ENST00000266509.7
solute carrier organic anion transporter family member 1C1
chr1_+_160190567 3.48 ENST00000368078.8
calsequestrin 1
chr5_-_39364484 3.44 ENST00000263408.5
complement C9
chr13_+_32031706 3.43 ENST00000542859.6
FRY microtubule binding protein
chr2_+_43838963 3.42 ENST00000272286.4
ATP binding cassette subfamily G member 8
chrX_+_30243715 3.42 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr5_-_161546708 3.39 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr12_-_7503744 3.36 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr11_+_61222347 3.25 ENST00000378149.9
pepsinogen A4
chrX_+_3041471 3.18 ENST00000381127.6
arylsulfatase F
chr13_-_46052712 3.10 ENST00000242848.8
ENST00000679008.1
ENST00000282007.7
zinc finger CCCH-type containing 13
chr16_+_2817180 3.09 ENST00000450020.7
serine protease 21
chr5_-_178995298 3.03 ENST00000517717.3
glutamate metabotropic receptor 6
chr18_-_69956924 3.02 ENST00000581982.5
ENST00000280200.8
CD226 molecule
chr3_+_148865288 3.01 ENST00000296046.4
carboxypeptidase A3
chr5_-_159330481 2.90 ENST00000231228.3
interleukin 12B
chr1_-_109613070 2.90 ENST00000351050.8
G protein subunit alpha transducin 2
chr18_-_24311495 2.86 ENST00000357041.8
oxysterol binding protein like 1A
chr17_+_46292733 2.81 ENST00000496930.5
leucine rich repeat containing 37A
chr12_-_8662703 2.80 ENST00000535336.5
microfibril associated protein 5
chr13_+_60396946 2.72 ENST00000377894.6
tudor domain containing 3
chr1_+_15476099 2.70 ENST00000375910.8
chymotrypsin like elastase 2B
chr1_-_147225568 2.69 ENST00000533174.5
ENST00000578284.5
flavin containing dimethylaniline monoxygenase 5
chrX_-_50200988 2.66 ENST00000358526.7
A-kinase anchoring protein 4
chr3_+_44874606 2.62 ENST00000296125.9
transglutaminase 4
chr12_-_46825949 2.61 ENST00000547477.5
ENST00000447411.5
ENST00000266579.9
solute carrier family 38 member 4
chr8_+_42697339 2.56 ENST00000289957.3
ENST00000534391.1
cholinergic receptor nicotinic beta 3 subunit
chrX_-_31178220 2.52 ENST00000681026.1
dystrophin
chr10_-_20897288 2.39 ENST00000377122.9
nebulette
chr10_+_113129285 2.36 ENST00000637574.1
transcription factor 7 like 2
chr3_-_119660580 2.36 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chr19_+_47035300 2.32 ENST00000439365.6
ENST00000594670.1
neuronal PAS domain protein 1
chr3_-_185254028 2.32 ENST00000440662.1
ENST00000456310.5
ENST00000231887.8
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
chrX_-_31178149 2.29 ENST00000679437.1
dystrophin
chr8_+_133191060 2.29 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
cellular communication network factor 4
chr11_+_30231000 2.29 ENST00000254122.8
ENST00000533718.2
ENST00000417547.1
follicle stimulating hormone subunit beta
chr1_-_147225309 2.27 ENST00000369272.7
ENST00000254090.9
ENST00000441068.6
flavin containing dimethylaniline monoxygenase 5
chr15_-_29968864 2.27 ENST00000356107.11
tight junction protein 1
chr18_+_21363593 2.26 ENST00000580732.6
GREB1 like retinoic acid receptor coactivator
chr5_-_128339191 2.25 ENST00000507835.5
fibrillin 2
chr18_+_34709356 2.22 ENST00000585446.1
ENST00000681241.1
dystrobrevin alpha
chr8_+_22999535 2.21 ENST00000251822.7
Rho related BTB domain containing 2
chr20_+_38304149 2.14 ENST00000262865.9
ENST00000642449.2
bactericidal permeability increasing protein
chrX_+_155997581 2.12 ENST00000244174.10
interleukin 9 receptor
chr7_-_127618137 2.07 ENST00000639438.3
paired box 4
chr4_-_73982019 2.06 ENST00000296029.4
platelet factor 4
chr14_+_24115299 2.06 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr7_+_91264426 2.06 ENST00000287934.4
frizzled class receptor 1
chr1_+_86468902 2.05 ENST00000394711.2
chloride channel accessory 1
chrX_+_87517784 1.98 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr5_+_141408000 1.94 ENST00000616430.1
protocadherin gamma subfamily B, 6
chr1_+_172452885 1.94 ENST00000367725.4
chromosome 1 open reading frame 105
chr16_-_3880678 1.91 ENST00000262367.10
CREB binding protein
chr11_-_33869816 1.86 ENST00000395833.7
LIM domain only 2
chr20_+_34241390 1.84 ENST00000374954.4
agouti signaling protein
chr16_+_2817230 1.76 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr2_-_55923775 1.74 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr9_-_92482350 1.71 ENST00000375543.2
asporin
chr1_+_50103903 1.66 ENST00000371827.5
ELAV like RNA binding protein 4
chr9_+_79572572 1.52 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr12_+_72272360 1.48 ENST00000547300.2
ENST00000261180.10
thyrotropin releasing hormone degrading enzyme
chr11_-_55936400 1.46 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr13_+_101489940 1.45 ENST00000376162.7
integrin subunit beta like 1
chr1_-_92483947 1.44 ENST00000370332.5
growth factor independent 1 transcriptional repressor
chr5_+_141408032 1.37 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr1_+_171090892 1.23 ENST00000367755.9
ENST00000479749.1
flavin containing dimethylaniline monoxygenase 3
chr4_+_73853290 1.23 ENST00000226524.4
platelet factor 4 variant 1
chr15_-_26939518 1.20 ENST00000541819.6
gamma-aminobutyric acid type A receptor subunit beta3
chr11_+_60056653 1.19 ENST00000278865.8
membrane spanning 4-domains A3
chr9_-_92482499 1.17 ENST00000375544.7
asporin
chr8_-_6563409 1.14 ENST00000325203.9
angiopoietin 2
chr7_-_108130349 1.14 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chrX_-_155071064 1.09 ENST00000369484.8
ENST00000369476.8
C-X9-C motif containing 4
mature T cell proliferation 1
chr12_-_10939263 1.09 ENST00000537503.2
taste 2 receptor member 14
chr9_-_27005659 1.05 ENST00000380055.6
leucine rich repeat containing 19
chr8_-_94262308 0.98 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr10_-_67696115 0.96 ENST00000433211.7
catenin alpha 3
chr22_-_31292445 0.96 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chrX_+_103628692 0.96 ENST00000372626.7
transcription elongation factor A like 1
chr9_+_116153783 0.89 ENST00000328252.4
pappalysin 1
chr11_+_60056587 0.87 ENST00000395032.6
ENST00000358152.6
membrane spanning 4-domains A3
chr8_-_6563238 0.86 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr6_-_10882037 0.84 ENST00000379491.5
glial cells missing transcription factor 2
chr12_-_7503841 0.81 ENST00000359156.8
CD163 molecule
chr14_+_22543179 0.79 ENST00000390534.1
T cell receptor alpha joining 3
chr5_-_147782681 0.75 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
janus kinase and microtubule interacting protein 2
chr21_-_26967057 0.71 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chrX_+_102307022 0.67 ENST00000604790.2
nuclear RNA export factor 2
chrX_+_136648214 0.66 ENST00000370628.2
CD40 ligand
chr3_-_179266971 0.57 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr3_+_108822759 0.56 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr17_-_31321743 0.44 ENST00000247270.3
ecotropic viral integration site 2A
chr6_-_41201128 0.41 ENST00000483722.2
triggering receptor expressed on myeloid cells like 2
chr15_+_71547226 0.37 ENST00000357769.4
ENST00000261862.7
thrombospondin type 1 domain containing 4
chr3_+_108822778 0.35 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr3_+_99638475 0.35 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
collagen type VIII alpha 1 chain
chr12_-_81369348 0.22 ENST00000548670.1
ENST00000541017.5
ENST00000541570.6
ENST00000553058.5
PTPRF interacting protein alpha 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.5 34.6 GO:0030185 nitric oxide transport(GO:0030185)
4.3 12.8 GO:0010847 regulation of chromatin assembly(GO:0010847)
4.2 8.4 GO:0046878 positive regulation of saliva secretion(GO:0046878)
3.9 19.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
3.5 10.6 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
3.5 10.5 GO:0018963 phthalate metabolic process(GO:0018963) cellular response to luteinizing hormone stimulus(GO:0071373)
3.1 9.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
2.5 10.1 GO:1903296 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
2.4 30.9 GO:0042908 xenobiotic transport(GO:0042908)
1.9 17.2 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
1.9 7.6 GO:0099558 maintenance of synapse structure(GO:0099558)
1.6 9.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.6 9.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.4 9.8 GO:0010044 response to aluminum ion(GO:0010044)
1.4 5.5 GO:0000023 maltose metabolic process(GO:0000023)
1.3 5.2 GO:0046485 ether lipid metabolic process(GO:0046485)
1.3 3.8 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
1.2 11.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.1 3.4 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
1.0 3.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.0 7.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.9 3.7 GO:0036269 swimming behavior(GO:0036269)
0.9 5.5 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.9 18.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.9 3.6 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.9 25.5 GO:0001502 cartilage condensation(GO:0001502)
0.9 3.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.8 8.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.7 5.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.7 2.9 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.7 2.1 GO:0035425 autocrine signaling(GO:0035425) canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.7 4.7 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.6 5.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.6 6.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.6 5.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.6 7.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.6 7.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 12.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.5 1.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.5 2.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4 4.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 2.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 8.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.4 6.9 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.4 1.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.4 9.1 GO:0071420 cellular response to histamine(GO:0071420)
0.4 16.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.3 1.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.7 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.3 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 2.3 GO:0060011 progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011)
0.3 2.9 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.3 2.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 2.1 GO:0071104 response to interleukin-9(GO:0071104)
0.3 4.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3 6.0 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 9.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 5.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.3 6.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 26.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 16.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.2 4.9 GO:0010842 retina layer formation(GO:0010842)
0.2 3.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 1.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 6.9 GO:0007628 adult walking behavior(GO:0007628)
0.2 2.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 3.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 9.1 GO:0016486 peptide hormone processing(GO:0016486)
0.2 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 6.8 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 0.8 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 2.3 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 12.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 5.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 10.5 GO:0021510 spinal cord development(GO:0021510)
0.1 4.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 8.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 2.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 2.7 GO:0044458 motile cilium assembly(GO:0044458)
0.1 2.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 3.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 2.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.9 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 2.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 5.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 4.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 2.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 3.7 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 4.2 GO:0006953 acute-phase response(GO:0006953)
0.1 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 20.4 GO:0043687 post-translational protein modification(GO:0043687)
0.0 7.4 GO:0007586 digestion(GO:0007586)
0.0 0.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 2.1 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 4.1 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 2.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 3.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 3.9 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 10.1 GO:0016567 protein ubiquitination(GO:0016567)
0.0 3.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.5 GO:0046718 viral entry into host cell(GO:0046718)
0.0 1.2 GO:0006805 xenobiotic metabolic process(GO:0006805)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 34.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.7 10.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.3 5.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.3 5.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.2 3.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.0 10.5 GO:0030061 mitochondrial crista(GO:0030061)
0.9 5.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.8 3.0 GO:0035841 new growing cell tip(GO:0035841)
0.8 9.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7 10.3 GO:0031906 late endosome lumen(GO:0031906)
0.7 2.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.7 3.4 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.6 3.5 GO:0014802 terminal cisterna(GO:0014802)
0.5 3.7 GO:0097165 nuclear stress granule(GO:0097165)
0.5 7.6 GO:0043083 synaptic cleft(GO:0043083)
0.5 5.0 GO:0005614 interstitial matrix(GO:0005614)
0.4 4.8 GO:0016013 syntrophin complex(GO:0016013)
0.4 7.8 GO:0031045 dense core granule(GO:0031045)
0.3 3.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 4.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 10.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 5.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 2.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 93.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 9.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 2.1 GO:1990909 Wnt signalosome(GO:1990909)
0.2 2.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 3.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 9.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 3.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 7.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 21.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 2.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 2.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 6.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 7.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 12.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.1 9.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 4.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 8.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 4.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.2 GO:0042383 sarcolemma(GO:0042383)
0.0 3.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 110.5 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 2.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 17.3 GO:0005730 nucleolus(GO:0005730)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 34.6 GO:0030492 hemoglobin binding(GO:0030492)
4.3 12.9 GO:0030305 heparanase activity(GO:0030305)
3.4 17.2 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
2.8 8.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
2.8 30.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.8 9.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.7 5.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.4 6.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.4 5.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
1.3 12.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.2 3.7 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.2 3.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 19.5 GO:0043522 leucine zipper domain binding(GO:0043522)
1.1 5.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.0 9.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.9 7.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.9 6.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.8 7.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8 2.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.8 9.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.7 5.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.7 5.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.7 4.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 13.0 GO:0017127 cholesterol transporter activity(GO:0017127)
0.5 2.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.5 7.2 GO:0015643 toxic substance binding(GO:0015643)
0.4 3.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 3.0 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.4 6.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 35.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 4.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 3.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4 10.1 GO:0043274 phospholipase binding(GO:0043274)
0.4 2.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 2.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.7 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.3 9.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 0.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 6.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 12.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 9.5 GO:0001671 ATPase activator activity(GO:0001671)
0.3 26.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 3.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 7.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3 4.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.3 4.5 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 4.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 18.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 8.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 27.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.9 GO:0043426 MRF binding(GO:0043426)
0.2 7.8 GO:0042056 chemoattractant activity(GO:0042056)
0.2 2.9 GO:0015248 sterol transporter activity(GO:0015248)
0.2 3.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 2.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 19.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 2.4 GO:0031005 filamin binding(GO:0031005)
0.1 8.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 3.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.6 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1 1.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 5.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 4.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 8.3 GO:0005179 hormone activity(GO:0005179)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 12.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 15.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 2.1 GO:0019955 cytokine binding(GO:0019955)
0.0 2.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 9.2 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 16.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 71.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 6.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 10.1 NABA COLLAGENS Genes encoding collagen proteins
0.2 16.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 6.9 ST GAQ PATHWAY G alpha q Pathway
0.1 2.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 19.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 25.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 12.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.8 PID BMP PATHWAY BMP receptor signaling
0.1 3.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 6.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 4.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 11.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.9 29.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.8 34.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.8 14.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.7 8.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.5 3.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.5 12.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.5 10.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 14.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.4 13.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 9.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 18.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 17.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 3.8 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 3.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 29.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 3.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 9.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 11.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 10.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 4.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 7.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 14.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 4.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1