Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for MEF2C

Z-value: 1.50

Motif logo

Transcription factors associated with MEF2C

Gene Symbol Gene ID Gene Info
ENSG00000081189.16 MEF2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Chg38_v1_chr5_-_88883199_88883227-0.082.2e-01Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr12_-_110920710 37.02 ENST00000546404.1
myosin light chain 2
chr12_-_110920568 36.73 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr11_+_1838970 26.47 ENST00000381911.6
troponin I2, fast skeletal type
chr22_-_35617321 25.25 ENST00000397326.7
ENST00000442617.1
myoglobin
chr11_-_19202004 23.36 ENST00000648719.1
cysteine and glycine rich protein 3
chr2_-_210303608 21.57 ENST00000341685.8
myosin light chain 1
chr17_+_39665340 20.95 ENST00000578283.1
ENST00000309889.3
titin-cap
chr17_+_4951758 20.94 ENST00000518175.1
enolase 3
chr11_-_19201976 20.92 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr11_+_1839602 19.68 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr3_-_52452828 19.47 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr3_+_8501846 18.29 ENST00000454244.4
LIM and cysteine rich domains 1
chr11_+_1839452 17.99 ENST00000381906.5
troponin I2, fast skeletal type
chr11_-_64759967 17.89 ENST00000377432.7
ENST00000164139.4
glycogen phosphorylase, muscle associated
chr16_-_31428325 17.67 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr12_+_101594849 17.22 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chrX_+_136196750 16.28 ENST00000539015.5
four and a half LIM domains 1
chrX_+_136197039 16.26 ENST00000370683.6
four and a half LIM domains 1
chr4_-_185775890 16.10 ENST00000437304.6
sorbin and SH3 domain containing 2
chrX_+_136197020 15.22 ENST00000370676.7
four and a half LIM domains 1
chr3_-_46863435 14.39 ENST00000395869.5
ENST00000653454.1
ENST00000292327.6
myosin light chain 3
chr7_+_76302665 13.77 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr8_+_141417902 12.30 ENST00000681443.1
protein tyrosine phosphatase 4A3
chr7_-_44065541 11.78 ENST00000297283.4
phosphoglycerate mutase 2
chr2_+_169509693 11.32 ENST00000284669.2
kelch like family member 41
chr11_+_1919694 10.77 ENST00000278317.11
ENST00000453458.5
ENST00000381557.6
ENST00000381579.7
ENST00000381589.7
ENST00000381563.8
ENST00000344578.8
ENST00000381558.6
troponin T3, fast skeletal type
chr1_-_201421718 10.31 ENST00000367312.5
ENST00000555340.6
ENST00000361379.9
ENST00000622580.4
troponin I1, slow skeletal type
chr14_-_23408265 10.05 ENST00000405093.9
myosin heavy chain 6
chr4_-_87529460 9.37 ENST00000418378.5
SPARC like 1
chr20_+_44582549 9.33 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr10_+_86668501 8.56 ENST00000623056.4
ENST00000263066.11
ENST00000429277.7
ENST00000361373.9
ENST00000372066.8
ENST00000372056.8
ENST00000623007.3
LIM domain binding 3
chr8_-_33599935 8.50 ENST00000523956.1
ENST00000256261.9
dual specificity phosphatase 26
chr3_+_8501807 8.42 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr1_+_160190567 7.85 ENST00000368078.8
calsequestrin 1
chr13_-_44474296 7.73 ENST00000611198.4
TSC22 domain family member 1
chr18_-_3219961 7.69 ENST00000356443.9
myomesin 1
chr10_-_73655984 7.62 ENST00000394810.3
synaptopodin 2 like
chr4_+_168497044 7.50 ENST00000505667.6
palladin, cytoskeletal associated protein
chr4_+_168497066 7.37 ENST00000261509.10
palladin, cytoskeletal associated protein
chr4_-_185775271 7.33 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr8_+_2045037 7.26 ENST00000262113.9
myomesin 2
chr10_-_73651013 6.90 ENST00000372873.8
synaptopodin 2 like
chr19_+_35138993 6.68 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr10_-_44978789 6.64 ENST00000448778.1
ENST00000298295.4
DEPP1 autophagy regulator
chr4_+_69995958 6.60 ENST00000381060.2
ENST00000246895.9
statherin
chr1_-_115768702 6.57 ENST00000261448.6
calsequestrin 2
chr16_+_30064274 6.48 ENST00000563060.6
aldolase, fructose-bisphosphate A
chr16_+_30064142 6.44 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr16_+_30064462 6.33 ENST00000412304.6
aldolase, fructose-bisphosphate A
chr12_+_6226136 6.30 ENST00000676764.1
ENST00000646407.1
CD9 molecule
chr4_+_54229261 5.88 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr12_-_9115907 5.82 ENST00000318602.12
alpha-2-macroglobulin
chr8_+_2045058 5.77 ENST00000523438.1
myomesin 2
chr19_+_6739650 5.57 ENST00000313285.12
ENST00000313244.14
ENST00000596758.5
thyroid hormone receptor interactor 10
chr1_-_31373067 5.46 ENST00000373713.7
fatty acid binding protein 3
chr3_+_179653032 5.29 ENST00000680587.1
ENST00000681064.1
ENST00000263966.8
ENST00000681358.1
ENST00000679749.1
ubiquitin specific peptidase 13
chr4_+_119135825 5.25 ENST00000307128.6
myozenin 2
chr3_+_194136138 5.12 ENST00000232424.4
hes family bHLH transcription factor 1
chr19_+_3933581 4.97 ENST00000593949.1
nicotinamide riboside kinase 2
chr1_-_19979607 4.83 ENST00000400520.8
ENST00000482011.2
ENST00000649436.1
phospholipase A2 group IIA
chr19_+_35138778 4.66 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr5_+_54455661 4.66 ENST00000302005.3
heat shock protein family B (small) member 3
chr9_+_97501622 4.65 ENST00000259365.9
tropomodulin 1
chr16_+_84294823 4.63 ENST00000568638.1
WAP four-disulfide core domain 1
chr14_-_23183641 4.60 ENST00000469263.5
ENST00000525062.1
ENST00000316902.12
ENST00000524758.1
solute carrier family 7 member 8
chr16_+_84294853 4.45 ENST00000219454.10
WAP four-disulfide core domain 1
chr3_+_138348592 4.44 ENST00000621127.4
ENST00000494949.5
muscle RAS oncogene homolog
chr5_+_141370236 4.25 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr1_-_114695613 4.17 ENST00000369538.4
adenosine monophosphate deaminase 1
chr3_+_179653129 4.13 ENST00000680008.1
ubiquitin specific peptidase 13
chr4_+_70050431 4.07 ENST00000511674.5
ENST00000246896.8
histatin 1
chr3_+_138348570 4.02 ENST00000423968.7
muscle RAS oncogene homolog
chr10_-_29634964 4.02 ENST00000375398.6
ENST00000355867.8
supervillin
chr14_-_21025490 4.02 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr11_-_31804067 4.00 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr7_+_30911845 3.97 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr1_-_230714112 3.97 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr1_-_114695533 3.88 ENST00000520113.7
adenosine monophosphate deaminase 1
chr16_+_6019016 3.79 ENST00000550418.6
RNA binding fox-1 homolog 1
chr21_+_25639272 3.63 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr14_-_21025000 3.62 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr3_+_138348823 3.55 ENST00000475711.5
ENST00000464896.5
muscle RAS oncogene homolog
chr8_+_141416141 3.54 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr11_-_47352693 3.53 ENST00000256993.8
ENST00000399249.6
ENST00000545968.6
myosin binding protein C3
chr10_-_113664033 3.49 ENST00000359988.4
ENST00000369360.7
ENST00000360478.7
ENST00000369358.8
nebulin related anchoring protein
chr16_+_6019071 3.49 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr4_+_41360759 3.48 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chr21_+_25639251 3.41 ENST00000480456.6
junctional adhesion molecule 2
chr6_-_169253835 3.26 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr7_-_56092974 3.26 ENST00000452681.6
ENST00000537360.5
phosphorylase kinase catalytic subunit gamma 1
chr18_-_3219849 3.18 ENST00000261606.11
myomesin 1
chr11_-_31803620 3.15 ENST00000639006.1
paired box 6
chr11_-_31803663 2.96 ENST00000638802.1
ENST00000638878.1
paired box 6
chr7_-_56092932 2.95 ENST00000446428.5
ENST00000432123.5
ENST00000297373.7
phosphorylase kinase catalytic subunit gamma 1
chr8_+_141416078 2.90 ENST00000349124.3
protein tyrosine phosphatase 4A3
chr1_+_156126525 2.85 ENST00000504687.6
ENST00000473598.6
lamin A/C
chr13_+_75760431 2.83 ENST00000321797.12
LIM domain 7
chrX_+_153781033 2.69 ENST00000370104.5
ENST00000370108.7
ENST00000370101.8
ENST00000430541.5
ENST00000370100.5
SRSF protein kinase 3
chr1_+_202010575 2.69 ENST00000367283.7
ENST00000367284.10
E74 like ETS transcription factor 3
chr4_+_41612892 2.66 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr11_-_31803960 2.53 ENST00000640872.1
ENST00000639109.1
ENST00000638629.1
ENST00000639386.2
paired box 6
chr19_+_35139440 2.52 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr17_-_10469558 2.52 ENST00000255381.2
myosin heavy chain 4
chr7_-_151519891 2.49 ENST00000262187.10
Ras homolog, mTORC1 binding
chr13_+_75760659 2.46 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chrX_+_153781001 2.40 ENST00000393786.7
SRSF protein kinase 3
chr19_-_893172 2.37 ENST00000325464.6
ENST00000312090.10
mediator complex subunit 16
chr1_-_201377652 2.36 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
troponin T2, cardiac type
chr4_-_121381007 2.35 ENST00000394427.3
pyroglutamylated RFamide peptide receptor
chr1_-_12618198 2.34 ENST00000616661.5
dehydrogenase/reductase 3
chr21_+_38256698 2.26 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
potassium inwardly rectifying channel subfamily J member 15
chr16_+_7332744 2.25 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr22_-_50578417 2.21 ENST00000312108.12
ENST00000395650.6
carnitine palmitoyltransferase 1B
chr9_-_33402449 2.20 ENST00000377425.8
aquaporin 7
chr3_-_192727500 2.17 ENST00000430714.5
ENST00000418610.1
ENST00000445105.7
ENST00000684728.1
ENST00000448795.5
ENST00000683935.1
ENST00000684282.1
ENST00000683451.1
fibroblast growth factor 12
chr11_+_3645105 2.10 ENST00000250693.2
ADP-ribosyltransferase 1
chr3_-_38029604 2.07 ENST00000334661.5
phospholipase C delta 1
chr16_+_7332839 2.05 ENST00000355637.9
RNA binding fox-1 homolog 1
chr19_-_893200 1.92 ENST00000269814.8
ENST00000395808.7
mediator complex subunit 16
chr8_-_17676484 1.89 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr15_+_42359454 1.89 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
calpain 3
chr5_+_114056017 1.88 ENST00000512097.9
potassium calcium-activated channel subfamily N member 2
chr20_+_50190821 1.85 ENST00000303004.5
CCAAT enhancer binding protein beta
chr4_+_94974984 1.82 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr3_+_4493471 1.79 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr7_+_154305105 1.76 ENST00000332007.7
dipeptidyl peptidase like 6
chr20_+_46029165 1.68 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chr4_+_94451857 1.67 ENST00000318007.9
ENST00000380180.7
ENST00000437932.5
ENST00000615540.4
ENST00000359265.8
ENST00000512274.1
ENST00000503974.5
ENST00000504489.3
ENST00000317968.9
ENST00000542407.5
PDZ and LIM domain 5
chr15_+_42359577 1.61 ENST00000357568.8
calpain 3
chr2_-_148020689 1.58 ENST00000457954.5
ENST00000392857.10
ENST00000540442.5
ENST00000535373.5
origin recognition complex subunit 4
chr7_+_142749465 1.58 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
serine protease 1
chr21_+_38256984 1.57 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr18_+_31447732 1.57 ENST00000257189.5
desmoglein 3
chr20_+_46029206 1.56 ENST00000243964.7
solute carrier family 12 member 5
chr2_+_232633551 1.51 ENST00000264059.8
EF-hand domain family member D1
chr10_+_61901678 1.51 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr20_+_58907981 1.45 ENST00000656419.1
GNAS complex locus
chr1_+_156126160 1.45 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr7_+_142760398 1.43 ENST00000632998.1
serine protease 2
chr9_+_35341830 1.40 ENST00000636694.1
unc-13 homolog B
chr5_-_16508788 1.39 ENST00000682142.1
reticulophagy regulator 1
chr2_+_172821575 1.38 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr9_+_68356603 1.35 ENST00000396396.6
phosphoglucomutase 5
chrY_-_23694579 1.30 ENST00000343584.10
PTPN13 like Y-linked pseudogene 3
chr15_+_67125707 1.26 ENST00000540846.6
SMAD family member 3
chr5_-_116574802 1.25 ENST00000343348.11
semaphorin 6A
chr13_-_35855758 1.22 ENST00000615680.4
doublecortin like kinase 1
chr2_-_148020754 1.20 ENST00000440042.1
ENST00000536575.5
origin recognition complex subunit 4
chr4_-_86360039 1.15 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
mitogen-activated protein kinase 10
chrX_-_129523436 1.12 ENST00000371123.5
ENST00000371121.5
ENST00000371122.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr5_-_11589019 1.11 ENST00000511377.5
catenin delta 2
chr9_+_5231413 1.09 ENST00000239316.4
insulin like 4
chr16_+_56191476 1.08 ENST00000262493.12
G protein subunit alpha o1
chr17_-_44123590 1.05 ENST00000336057.9
histone deacetylase 5
chr8_-_23854796 1.01 ENST00000290271.7
stanniocalcin 1
chr10_+_69801874 1.01 ENST00000357811.8
collagen type XIII alpha 1 chain
chrX_-_15384402 1.00 ENST00000297904.4
vascular endothelial growth factor D
chrX_-_47574738 1.00 ENST00000640721.1
synapsin I
chr2_+_238138661 1.00 ENST00000409223.2
kelch like family member 30
chr1_-_21345531 0.94 ENST00000649812.1
endothelin converting enzyme 1
chr17_+_67044530 0.92 ENST00000226021.5
calcium voltage-gated channel auxiliary subunit gamma 1
chr3_+_4493442 0.91 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
inositol 1,4,5-trisphosphate receptor type 1
chr10_+_69801892 0.91 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr17_-_44123628 0.88 ENST00000587135.1
ENST00000225983.10
ENST00000682912.1
ENST00000588703.5
histone deacetylase 5
chr21_-_40847149 0.86 ENST00000400454.6
DS cell adhesion molecule
chr7_+_5879827 0.84 ENST00000416608.5
oncomodulin
chr5_-_16508990 0.84 ENST00000399793.6
reticulophagy regulator 1
chr17_-_69244846 0.84 ENST00000269081.8
ATP binding cassette subfamily A member 10
chr1_+_183636065 0.81 ENST00000304685.8
ral guanine nucleotide dissociation stimulator like 1
chr9_-_107489754 0.81 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr5_-_16508812 0.80 ENST00000683414.1
reticulophagy regulator 1
chr9_-_33402551 0.78 ENST00000297988.6
ENST00000624075.3
ENST00000625032.1
ENST00000625109.3
aquaporin 7
chr12_-_130716264 0.74 ENST00000643940.1
RIMS binding protein 2
chr2_+_219253243 0.72 ENST00000490341.3
tubulin alpha 4b
chr1_-_114780624 0.70 ENST00000060969.6
ENST00000369528.9
suppressor of IKBKE 1
chr10_+_69802424 0.70 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr11_+_70078291 0.68 ENST00000355303.9
anoctamin 1
chr8_+_40153475 0.66 ENST00000315792.5
transcriptional and immune response regulator
chr11_-_116837586 0.59 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
apolipoprotein A1
chr10_-_60141004 0.56 ENST00000355288.6
ankyrin 3
chr3_+_4493340 0.55 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
inositol 1,4,5-trisphosphate receptor type 1
chr3_-_101320558 0.53 ENST00000193391.8
interphotoreceptor matrix proteoglycan 2
chr1_-_145910031 0.53 ENST00000369304.8
integrin subunit alpha 10
chrX_+_47370578 0.51 ENST00000377073.4
zinc finger protein 157
chr7_-_151520080 0.50 ENST00000496004.5
Ras homolog, mTORC1 binding
chr2_+_219279330 0.49 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr3_+_113897470 0.48 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr1_+_170664121 0.48 ENST00000239461.11
paired related homeobox 1
chr6_-_46015812 0.47 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chr4_-_23890035 0.45 ENST00000507380.1
ENST00000264867.7
PPARG coactivator 1 alpha
chr17_-_1486124 0.44 ENST00000575158.5
myosin IC
chr4_-_39638846 0.42 ENST00000295958.10
small integral membrane protein 14
chr3_+_46883337 0.41 ENST00000313049.9
parathyroid hormone 1 receptor
chr2_+_33436304 0.41 ENST00000402538.7
RAS guanyl releasing protein 3
chr6_+_160702238 0.39 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr9_+_127802858 0.37 ENST00000393706.6
ENST00000630236.2
ENST00000373247.7
ENST00000373228.5
folylpolyglutamate synthase
chr19_+_10013468 0.35 ENST00000591589.3
retinol dehydrogenase 8
chr4_+_109912877 0.35 ENST00000265171.10
ENST00000509793.5
ENST00000652245.1
epidermal growth factor
chr2_+_203936755 0.31 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr5_-_16508951 0.30 ENST00000682628.1
reticulophagy regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.0 65.2 GO:0035995 detection of muscle stretch(GO:0035995)
6.7 73.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
6.5 19.5 GO:0002086 diaphragm contraction(GO:0002086)
3.7 44.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
3.4 13.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
3.1 9.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
2.8 8.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.8 25.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.3 13.9 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
2.2 140.8 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
2.0 11.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.0 5.9 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.9 5.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.7 5.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
1.6 7.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.3 4.0 GO:0033326 nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) positive regulation of saliva secretion(GO:0046878) cellular response to mercury ion(GO:0071288) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
1.3 4.0 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.2 18.7 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.1 19.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.0 7.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.9 25.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9 26.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.9 5.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.9 17.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.8 6.6 GO:0046541 saliva secretion(GO:0046541)
0.8 11.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.8 8.1 GO:0032264 IMP salvage(GO:0032264)
0.8 14.9 GO:0003334 keratinocyte development(GO:0003334)
0.7 3.0 GO:0015793 glycerol transport(GO:0015793)
0.7 12.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.7 4.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.6 24.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.6 20.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6 45.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.6 9.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6 6.3 GO:0009414 response to water deprivation(GO:0009414)
0.5 3.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.5 1.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 7.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 3.6 GO:0061709 reticulophagy(GO:0061709)
0.4 3.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.4 3.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 3.0 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.3 4.8 GO:0036149 phosphatidylglycerol acyl-chain remodeling(GO:0036148) phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 0.8 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.3 1.8 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.3 8.6 GO:0045214 sarcomere organization(GO:0045214)
0.2 2.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 1.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 16.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.9 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 5.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 2.7 GO:0060056 mammary gland involution(GO:0060056)
0.2 2.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 11.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.6 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.9 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 4.6 GO:0015695 organic cation transport(GO:0015695)
0.1 1.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 4.1 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 9.1 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 2.2 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1 0.7 GO:0015705 iodide transport(GO:0015705)
0.1 0.9 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 12.0 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 5.1 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 2.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 3.6 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.1 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.1 2.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 1.5 GO:0016577 histone demethylation(GO:0016577)
0.0 5.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 5.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 3.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 2.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.4 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 4.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 4.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 2.2 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 77.3 GO:0097512 cardiac myofibril(GO:0097512)
5.1 107.0 GO:0005861 troponin complex(GO:0005861)
3.6 10.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
2.6 20.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
2.1 78.8 GO:0005859 muscle myosin complex(GO:0005859)
1.4 14.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.4 17.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.0 4.0 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.9 3.5 GO:0005927 muscle tendon junction(GO:0005927)
0.9 2.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.9 29.3 GO:0031430 M band(GO:0031430)
0.8 149.7 GO:0030018 Z disc(GO:0030018)
0.8 13.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6 6.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.5 3.2 GO:0005955 calcineurin complex(GO:0005955)
0.4 4.0 GO:0036449 microtubule minus-end(GO:0036449)
0.4 4.3 GO:0005638 lamin filament(GO:0005638)
0.3 1.4 GO:0044305 calyx of Held(GO:0044305)
0.2 4.6 GO:0036379 myofilament(GO:0036379)
0.2 5.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.9 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.2 0.8 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 1.1 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 14.3 GO:0031091 platelet alpha granule(GO:0031091)
0.1 3.6 GO:0016592 mediator complex(GO:0016592)
0.1 5.8 GO:0016528 sarcoplasm(GO:0016528)
0.1 6.2 GO:0005902 microvillus(GO:0005902)
0.1 3.2 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.0 10.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 23.9 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 7.3 GO:0030426 growth cone(GO:0030426)
0.0 26.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 12.4 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.6 GO:0005912 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.8 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 6.4 GO:0016607 nuclear speck(GO:0016607)
0.0 37.2 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 20.9 GO:0051373 FATZ binding(GO:0051373)
6.0 83.6 GO:0031014 troponin T binding(GO:0031014)
4.7 99.7 GO:0032036 myosin heavy chain binding(GO:0032036)
4.6 13.8 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
4.5 49.5 GO:0031433 telethonin binding(GO:0031433)
4.5 17.9 GO:0008184 glycogen phosphorylase activity(GO:0008184)
3.3 13.1 GO:0030172 troponin C binding(GO:0030172)
3.2 68.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
2.6 20.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.4 11.8 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.2 6.6 GO:0046848 hydroxyapatite binding(GO:0046848)
2.1 8.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.1 18.7 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
2.0 10.1 GO:0017018 myosin phosphatase activity(GO:0017018)
2.0 5.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.9 5.8 GO:0019959 interleukin-8 binding(GO:0019959)
1.8 5.5 GO:0070538 oleic acid binding(GO:0070538)
1.7 19.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.7 25.2 GO:0005344 oxygen transporter activity(GO:0005344)
1.3 9.4 GO:1904288 BAT3 complex binding(GO:1904288)
1.2 5.0 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.2 6.9 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.9 3.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.9 23.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 6.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.6 17.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 4.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 2.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.4 9.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4 2.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 3.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 1.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.3 2.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 2.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.3 4.6 GO:0019534 toxin transporter activity(GO:0019534)
0.3 23.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 4.6 GO:0005523 tropomyosin binding(GO:0005523)
0.3 0.6 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.3 10.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.3 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 3.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 4.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 0.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 38.8 GO:0044325 ion channel binding(GO:0044325)
0.2 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 9.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 3.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 9.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.1 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 9.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 7.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 1.5 GO:0051429 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.8 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 20.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 27.3 GO:0003779 actin binding(GO:0003779)
0.1 6.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 1.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.4 GO:0030552 cAMP binding(GO:0030552)
0.0 5.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 4.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 11.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 8.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 11.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 73.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 22.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 6.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 4.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 13.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.2 19.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 4.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 3.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 10.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 10.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 5.6 PID INSULIN PATHWAY Insulin Pathway
0.1 6.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 11.7 PID CDC42 PATHWAY CDC42 signaling events
0.1 5.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 4.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 7.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID BMP PATHWAY BMP receptor signaling
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 258.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.9 52.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.9 24.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.5 6.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 12.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 8.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 4.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 6.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 1.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.5 REACTOME DEFENSINS Genes involved in Defensins
0.2 3.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 13.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 4.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 9.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 4.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 6.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 6.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 3.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins