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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 3.08

Motif logo

Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
ENSG00000185155.12 MIXL1
ENSG00000169840.5 GSX1
ENSG00000188909.5 BSX
ENSG00000106511.6 MEOX2
ENSG00000121454.6 LHX4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MIXL1hg38_v1_chr1_+_226223618_2262236700.202.4e-03Click!
MEOX2hg38_v1_chr7_-_15686671_156866890.092.1e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_40196907 23.78 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr4_+_40197023 22.29 ENST00000381799.10
ras homolog family member H
chr12_-_14950606 21.89 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr13_-_46142834 18.77 ENST00000674665.1
lymphocyte cytosolic protein 1
chr2_-_157444044 15.89 ENST00000264192.8
cytohesin 1 interacting protein
chr2_+_68734773 15.28 ENST00000409202.8
Rho GTPase activating protein 25
chr1_-_92486916 14.24 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr3_-_18438767 14.23 ENST00000454909.6
SATB homeobox 1
chr13_-_41019289 13.94 ENST00000239882.7
E74 like ETS transcription factor 1
chr12_-_91153149 12.88 ENST00000550758.1
decorin
chr1_+_110873135 12.68 ENST00000271324.6
CD53 molecule
chr2_+_90234809 12.15 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr2_-_207167220 12.15 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr1_+_174875505 11.74 ENST00000486220.5
RAB GTPase activating protein 1 like
chr2_+_68734861 11.62 ENST00000467265.5
Rho GTPase activating protein 25
chr7_-_25228485 11.51 ENST00000222674.2
neuropeptide VF precursor
chr1_+_198638968 11.32 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr5_+_67004618 10.07 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr6_-_32941018 10.01 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr3_+_108822778 9.95 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr3_+_108822759 9.85 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr12_-_6124662 9.83 ENST00000261405.10
von Willebrand factor
chr14_+_92323154 9.60 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr1_-_150765735 8.60 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr11_-_117876892 8.40 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr2_+_87338511 8.20 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr11_-_117876719 8.18 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr12_+_55932028 8.18 ENST00000394147.5
ENST00000551156.5
ENST00000553783.5
ENST00000557080.5
ENST00000432422.7
ENST00000556001.5
diacylglycerol kinase alpha
chr2_+_90172802 7.98 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr2_+_90038848 7.98 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr6_+_26365176 7.76 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr6_+_26365215 7.59 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr18_+_34976928 7.53 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr6_+_139135063 6.77 ENST00000367658.3
hdc homolog, cell cycle regulator
chr12_+_25052634 6.73 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr7_-_87713287 6.66 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1
chr11_-_33892010 6.58 ENST00000257818.3
LIM domain only 2
chr7_+_50308672 6.39 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKAROS family zinc finger 1
chr5_+_157269317 6.36 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr11_-_117877463 6.35 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr8_+_28891304 6.23 ENST00000355231.9
homeobox containing 1
chr1_-_150765785 6.17 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr14_-_106470788 6.07 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr18_-_14132423 6.02 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr14_+_22462932 5.95 ENST00000390477.2
T cell receptor delta constant
chr6_+_31615984 5.94 ENST00000376049.4
allograft inflammatory factor 1
chr2_-_135530561 5.94 ENST00000536680.5
ENST00000401392.5
zinc finger RANBP2-type containing 3
chr19_+_49513353 5.91 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr7_+_92057602 5.86 ENST00000491695.2
A-kinase anchoring protein 9
chr12_+_25052512 5.67 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr8_-_85341705 5.63 ENST00000517618.5
carbonic anhydrase 1
chr2_+_102418642 5.61 ENST00000264260.6
interleukin 18 receptor accessory protein
chr14_+_61187544 5.54 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chrX_+_1591590 5.51 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr13_-_99258366 5.49 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr6_+_26402237 5.48 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr6_-_25042003 5.40 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr1_-_24964984 5.33 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr11_+_121576760 5.30 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr3_+_73061659 5.26 ENST00000533473.1
endogenous Bornavirus like nucleoprotein 2
chr2_+_90209873 5.23 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr2_-_88979016 5.21 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_30146993 5.19 ENST00000261353.9
ENST00000402003.7
yippee like 5
chr2_-_24328113 5.13 ENST00000622089.4
intersectin 2
chr6_+_106360668 5.08 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr5_-_39219555 5.03 ENST00000512982.4
ENST00000351578.12
ENST00000509072.5
ENST00000504542.1
ENST00000506557.5
FYN binding protein 1
chr4_-_70666492 4.93 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr4_-_46909235 4.93 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr2_+_169069537 4.89 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr2_+_90100235 4.85 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr11_+_57597563 4.77 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr6_+_131250375 4.75 ENST00000474850.2
A-kinase anchoring protein 7
chr6_+_26365159 4.74 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
butyrophilin subfamily 3 member A2
chr2_+_30146941 4.72 ENST00000379520.7
ENST00000379519.7
yippee like 5
chr7_+_70596078 4.71 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr6_-_26234978 4.65 ENST00000244534.7
H1.3 linker histone, cluster member
chr10_+_70404129 4.61 ENST00000373218.5
eukaryotic translation initiation factor 4E binding protein 2
chr12_+_26195313 4.60 ENST00000422622.3
sarcospan
chr10_+_84194527 4.60 ENST00000623527.4
cadherin related family member 1
chr16_+_86566821 4.54 ENST00000649859.1
forkhead box C2
chrX_+_136648138 4.44 ENST00000370629.7
CD40 ligand
chr1_-_1390943 4.44 ENST00000408952.8
cyclin L2
chr19_+_57633161 4.44 ENST00000541801.5
ENST00000347302.7
ENST00000240731.5
ENST00000254182.11
ENST00000391703.3
zinc finger protein 211
chr8_-_85341659 4.40 ENST00000522389.5
carbonic anhydrase 1
chr11_-_108222594 4.39 ENST00000278612.9
nuclear protein, coactivator of histone transcription
chr18_+_34593312 4.39 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chrX_-_18672101 4.29 ENST00000379984.4
retinoschisin 1
chr3_-_138329839 4.29 ENST00000333911.9
ENST00000383180.6
NME/NM23 family member 9
chrX_+_22032301 4.27 ENST00000379374.5
phosphate regulating endopeptidase homolog X-linked
chr13_+_30735523 4.20 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr6_+_26402289 4.19 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr14_-_103715433 4.16 ENST00000554913.5
ENST00000555055.6
ENST00000554974.5
ENST00000553361.5
ENST00000555964.5
ENST00000556682.5
ENST00000553332.5
ENST00000352127.11
X-ray repair cross complementing 3
chr1_+_174700413 4.10 ENST00000529145.6
ENST00000325589.9
RAB GTPase activating protein 1 like
chr18_+_74148508 4.06 ENST00000580087.5
ENST00000169551.11
translocase of inner mitochondrial membrane 21
chr12_-_9607903 4.05 ENST00000229402.4
killer cell lectin like receptor B1
chr12_+_26195647 4.03 ENST00000535504.1
sarcospan
chr2_-_86105839 4.03 ENST00000263857.11
RNA polymerase I subunit A
chr6_-_32589833 4.02 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr4_-_8871817 3.95 ENST00000400677.5
H6 family homeobox 1
chr7_+_149838365 3.91 ENST00000460379.1
ENST00000223210.5
zinc finger protein 862
chr2_+_206159580 3.91 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr1_-_113871665 3.89 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr16_+_68085552 3.85 ENST00000329524.8
nuclear factor of activated T cells 3
chr6_-_36547400 3.83 ENST00000229812.8
serine/threonine kinase 38
chr1_-_152414256 3.83 ENST00000271835.3
cornulin
chr3_-_12545499 3.81 ENST00000564146.4
MKRN2 opposite strand
chr12_+_25052732 3.80 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr18_-_55587335 3.79 ENST00000638154.3
transcription factor 4
chr6_-_32816910 3.77 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr11_-_105035113 3.76 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr11_-_2301859 3.75 ENST00000456145.2
ENST00000381153.8
chromosome 11 open reading frame 21
chr18_-_55510753 3.69 ENST00000543082.5
transcription factor 4
chrX_+_108091752 3.69 ENST00000457035.5
ENST00000372232.8
autophagy related 4A cysteine peptidase
chr4_+_87832917 3.67 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr4_-_76007501 3.67 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr6_-_31139063 3.63 ENST00000259845.5
psoriasis susceptibility 1 candidate 2
chr9_+_133636355 3.60 ENST00000393056.8
dopamine beta-hydroxylase
chr1_-_247458105 3.58 ENST00000641149.1
ENST00000641527.1
olfactory receptor family 2 subfamily B member 11
chr18_-_55351977 3.58 ENST00000643689.1
transcription factor 4
chrX_+_108091665 3.53 ENST00000345734.7
autophagy related 4A cysteine peptidase
chr10_-_49762335 3.50 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr6_-_52840843 3.39 ENST00000370989.6
glutathione S-transferase alpha 5
chr18_+_34593392 3.38 ENST00000684377.1
dystrobrevin alpha
chr18_+_31447732 3.38 ENST00000257189.5
desmoglein 3
chr11_-_36598221 3.36 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr1_+_180632001 3.31 ENST00000367590.9
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr2_+_206159884 3.28 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chr10_-_49762276 3.26 ENST00000374103.9
oxoglutarate dehydrogenase L
chr5_+_177426701 3.25 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr1_-_158426237 3.24 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr12_+_54280842 3.23 ENST00000678077.1
ENST00000548688.5
heterogeneous nuclear ribonucleoprotein A1
chr10_-_73591330 3.23 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr14_+_22495890 3.21 ENST00000390494.1
T cell receptor alpha joining 43
chr12_-_10453330 3.18 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chrX_-_123623155 3.15 ENST00000618150.4
THO complex 2
chr12_-_91179355 3.15 ENST00000550563.5
ENST00000546370.5
decorin
chr18_+_34978244 3.12 ENST00000436190.6
microtubule associated protein RP/EB family member 2
chr14_+_22508602 3.09 ENST00000390504.1
T cell receptor alpha joining 33
chrX_+_108045050 3.06 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr19_-_13953302 3.03 ENST00000585607.1
ENST00000538517.6
ENST00000587458.1
ENST00000538371.6
podocan like 1
chr7_-_83649097 3.02 ENST00000643230.2
semaphorin 3E
chr16_+_68085344 3.02 ENST00000575270.5
ENST00000346183.8
nuclear factor of activated T cells 3
chr12_+_54280663 3.01 ENST00000677375.1
ENST00000677210.1
ENST00000677385.1
ENST00000677249.1
ENST00000550482.2
ENST00000679101.1
ENST00000340913.11
ENST00000547708.5
ENST00000551702.5
ENST00000676794.1
ENST00000330752.12
ENST00000678690.1
ENST00000678919.1
ENST00000547276.5
heterogeneous nuclear ribonucleoprotein A1
chr2_-_88861258 2.97 ENST00000390240.2
immunoglobulin kappa joining 3
chr4_+_7043315 2.96 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr2_+_90159840 2.93 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr5_+_177426667 2.92 ENST00000355472.10
G protein-coupled receptor kinase 6
chrX_+_108044967 2.88 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr4_+_94995919 2.86 ENST00000509540.6
bone morphogenetic protein receptor type 1B
chr16_+_11965234 2.84 ENST00000562385.1
TNF receptor superfamily member 17
chr8_+_109362453 2.84 ENST00000378402.10
PKHD1 like 1
chr2_+_169584332 2.83 ENST00000414307.6
ENST00000433207.6
ENST00000678088.1
ENST00000676508.1
ENST00000260970.8
ENST00000409714.7
peptidylprolyl isomerase G
chr5_+_141364231 2.83 ENST00000611914.1
protocadherin gamma subfamily A, 5
chr12_-_9760893 2.82 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr3_-_167474026 2.81 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr12_+_26195543 2.79 ENST00000242729.7
sarcospan
chr6_-_39725387 2.79 ENST00000287152.12
kinesin family member 6
chr11_-_124445696 2.78 ENST00000642064.1
olfactory receptor family 8 subfamily B member 8
chr2_-_89143133 2.78 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr6_-_99425269 2.77 ENST00000647811.1
ENST00000481229.2
ENST00000369239.10
ENST00000681611.1
ENST00000681615.1
ENST00000438806.5
PNN interacting serine and arginine rich protein
chr3_+_4680617 2.77 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr2_-_89100352 2.76 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr11_+_60455839 2.73 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chrX_+_15790446 2.71 ENST00000380308.7
ENST00000307771.8
zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
chr12_-_118190510 2.70 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr6_+_72216745 2.70 ENST00000517827.5
regulating synaptic membrane exocytosis 1
chr7_-_38265678 2.70 ENST00000443402.6
T cell receptor gamma constant 1
chr14_+_99481395 2.64 ENST00000389879.9
ENST00000557441.5
ENST00000555049.5
ENST00000555842.1
cyclin K
chr12_-_114403898 2.64 ENST00000526441.1
T-box transcription factor 5
chr7_+_116222804 2.64 ENST00000393481.6
testin LIM domain protein
chr11_-_117876612 2.63 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chrX_+_136648214 2.61 ENST00000370628.2
CD40 ligand
chr2_-_89027700 2.61 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr8_+_38728186 2.61 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chrX_-_77634229 2.61 ENST00000675732.1
ATRX chromatin remodeler
chr11_-_13496018 2.60 ENST00000529816.1
parathyroid hormone
chr5_-_24644968 2.59 ENST00000264463.8
cadherin 10
chr6_+_42746958 2.59 ENST00000614467.4
BRD4 interacting chromatin remodeling complex associated protein like
chr2_-_165203870 2.58 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr8_+_49911396 2.56 ENST00000642720.2
syntrophin gamma 1
chr3_-_108529322 2.56 ENST00000273353.4
myosin heavy chain 15
chr19_-_45178200 2.55 ENST00000592647.1
ENST00000006275.8
ENST00000588062.5
ENST00000585934.1
trafficking protein particle complex 6A
chr2_+_113005454 2.54 ENST00000259211.7
interleukin 36 alpha
chr15_+_74788542 2.50 ENST00000567571.5
C-terminal Src kinase
chr11_+_24496988 2.49 ENST00000336930.11
leucine zipper protein 2
chr14_-_21580076 2.48 ENST00000641040.1
ENST00000641185.1
olfactory receptor family 10 subfamily G member 3
chr4_-_25863537 2.48 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr6_+_6588082 2.47 ENST00000379953.6
lymphocyte antigen 86
chr16_+_68085420 2.47 ENST00000349223.9
nuclear factor of activated T cells 3
chr6_+_72216442 2.47 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr6_+_150721073 2.45 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr12_-_111685720 2.44 ENST00000327551.6
BRCA1 associated protein
chrX_-_45200828 2.43 ENST00000398000.7
divergent protein kinase domain 2B
chr17_+_46923075 2.43 ENST00000640608.1
ENST00000638634.1
ENST00000623037.2
ENST00000225567.9
ENST00000415811.7
ENST00000576910.7
ENST00000573224.2
ENST00000640621.1
ENST00000638892.1
ENST00000638838.1
ENST00000638216.1
ENST00000575949.6
ENST00000640806.1
ENST00000640269.1
ENST00000640443.1
ENST00000638697.1
ENST00000640051.2
ENST00000640007.1
ENST00000640711.1
ENST00000640495.1
ENST00000638374.1
ENST00000571048.1
ENST00000639287.1
ENST00000640138.1
ENST00000570879.2
ENST00000640068.1
ENST00000393456.7
ENST00000639031.1
golgi SNAP receptor complex member 2
chr6_-_22297028 2.42 ENST00000306482.2
prolactin
chr12_+_18261511 2.40 ENST00000538779.6
ENST00000433979.6
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr10_+_52128343 2.38 ENST00000672084.1
protein kinase cGMP-dependent 1
chr2_+_90082635 2.38 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr2_-_89213917 2.37 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr2_+_89884740 2.36 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.9 GO:0071461 cellular response to redox state(GO:0071461)
4.9 14.8 GO:0034769 basement membrane disassembly(GO:0034769)
4.7 14.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
3.8 11.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
3.5 14.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
3.3 19.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
2.4 7.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
2.0 6.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
2.0 5.9 GO:0036292 DNA rewinding(GO:0036292)
1.8 5.5 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.8 7.2 GO:0051697 protein delipidation(GO:0051697)
1.8 5.3 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.6 4.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.6 4.7 GO:0098582 innate vocalization behavior(GO:0098582)
1.5 4.5 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.5 6.0 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.4 4.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.4 17.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.3 3.8 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.3 3.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.3 3.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.2 6.2 GO:1903936 cellular response to sodium arsenite(GO:1903936)
1.2 5.9 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
1.1 34.0 GO:0072643 interferon-gamma secretion(GO:0072643)
1.1 15.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.1 3.4 GO:0002326 B cell lineage commitment(GO:0002326)
1.1 5.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.1 5.4 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
1.0 11.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
1.0 3.9 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.0 2.9 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.9 2.6 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.9 2.6 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.9 17.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.9 2.6 GO:0099404 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.8 4.9 GO:0097338 response to clozapine(GO:0097338)
0.8 3.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.8 2.3 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.7 5.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.7 3.6 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.7 5.7 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.7 2.8 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.7 13.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.7 1.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.7 43.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.7 15.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.6 1.9 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.6 0.6 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.6 1.9 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.6 1.9 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.6 16.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.6 2.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.6 1.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.6 0.6 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 1.7 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.6 3.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 3.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 4.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.5 4.9 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 3.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 1.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.5 2.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.5 1.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 4.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.5 1.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 2.9 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.5 1.0 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.5 1.4 GO:0051295 meiotic cell cycle phase transition(GO:0044771) establishment of meiotic spindle localization(GO:0051295) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 1.8 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.4 1.3 GO:0002912 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.4 4.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 3.0 GO:0044245 polysaccharide digestion(GO:0044245)
0.4 2.6 GO:1903232 melanosome assembly(GO:1903232)
0.4 1.3 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.4 5.9 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 5.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.4 2.5 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.4 2.5 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4 6.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.4 0.4 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.4 2.0 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.4 3.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 2.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 2.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 0.4 GO:0070662 mast cell proliferation(GO:0070662)
0.4 1.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.4 9.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 1.5 GO:0002384 hepatic immune response(GO:0002384)
0.4 7.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.4 1.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.4 2.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 1.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.4 6.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.4 1.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.4 50.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 2.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 1.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.3 1.3 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.3 7.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 4.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 6.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 0.6 GO:0072106 ureteric bud formation(GO:0060676) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.3 0.9 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 4.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.3 0.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.3 2.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.3 4.4 GO:0009642 response to light intensity(GO:0009642)
0.3 7.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 1.5 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.3 2.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 0.9 GO:0072143 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.3 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 1.7 GO:0061743 motor learning(GO:0061743)
0.3 1.7 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.3 1.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 2.5 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 2.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.3 1.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 1.6 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.3 0.5 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.3 2.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.3 0.8 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 1.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 2.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 38.1 GO:0002377 immunoglobulin production(GO:0002377)
0.2 19.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 1.7 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 1.0 GO:0043091 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.2 4.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 6.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 4.7 GO:0097186 amelogenesis(GO:0097186)
0.2 6.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 0.7 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 3.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 2.1 GO:0070475 rRNA base methylation(GO:0070475)
0.2 0.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 2.9 GO:0070307 lens fiber cell development(GO:0070307)
0.2 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 1.6 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 3.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 0.9 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 11.2 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.4 GO:0055089 fatty acid homeostasis(GO:0055089)
0.2 1.4 GO:0061087 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 1.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 3.8 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 1.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.8 GO:0098712 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) amino acid import across plasma membrane(GO:0089718) L-glutamate import across plasma membrane(GO:0098712)
0.2 1.2 GO:0048840 otolith development(GO:0048840)
0.2 0.6 GO:1904386 cellular response to mycotoxin(GO:0036146) response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
0.2 0.6 GO:0022018 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.2 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.6 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.2 1.5 GO:0035878 nail development(GO:0035878)
0.2 0.4 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 2.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 3.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.2 0.4 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.2 0.4 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 1.1 GO:0007296 vitellogenesis(GO:0007296)
0.2 5.8 GO:0070207 protein homotrimerization(GO:0070207)
0.2 0.4 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.2 8.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 5.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 3.2 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.2 2.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 2.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 0.3 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.2 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2 0.5 GO:0060023 soft palate development(GO:0060023)
0.2 0.3 GO:2000617 positive regulation of histone H3-K9 acetylation(GO:2000617)
0.2 16.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.2 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.5 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 0.2 GO:0035926 chemokine (C-C motif) ligand 2 secretion(GO:0035926) chemokine (C-X-C motif) ligand 2 production(GO:0072567) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000341) positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.2 0.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 1.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.9 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 2.2 GO:0001562 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.1 1.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 1.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.8 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.3 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.1 0.6 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.8 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 1.3 GO:0015871 choline transport(GO:0015871)
0.1 0.4 GO:0061011 hepatic duct development(GO:0061011)
0.1 5.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 1.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 2.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.0 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 1.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 1.8 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.9 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 3.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.3 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 3.9 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.0 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.5 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 1.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.8 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 1.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.5 GO:0046618 drug export(GO:0046618)
0.1 1.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 2.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.7 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.0 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.5 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.5 GO:0034694 response to prostaglandin(GO:0034694)
0.1 0.8 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 1.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.1 0.3 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 0.8 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.1 0.2 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.4 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 3.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 4.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.1 1.3 GO:0033189 response to vitamin A(GO:0033189)
0.1 1.1 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.1 0.9 GO:0006069 ethanol oxidation(GO:0006069)
0.1 5.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.5 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.7 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 1.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0001554 luteolysis(GO:0001554)
0.1 0.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 4.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.2 GO:0072708 response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709)
0.1 2.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 1.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 2.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 1.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 2.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 4.6 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 1.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 1.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 3.0 GO:0019228 neuronal action potential(GO:0019228)
0.1 15.7 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.1 3.6 GO:0007595 lactation(GO:0007595)
0.1 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.1 0.2 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 1.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.1 2.2 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 0.5 GO:0035860 gastro-intestinal system smooth muscle contraction(GO:0014831) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.4 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.2 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of cAMP-dependent protein kinase activity(GO:2000481) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.1 GO:0048541 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.1 3.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 2.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 6.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:0044320 cellular response to leptin stimulus(GO:0044320)
0.1 1.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.1 5.3 GO:0045471 response to ethanol(GO:0045471)
0.1 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 1.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 3.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 3.4 GO:1905037 autophagosome organization(GO:1905037)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 1.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 1.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 3.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.7 GO:0009584 detection of visible light(GO:0009584)
0.0 1.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 1.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0045761 negative regulation of adenylate cyclase activity(GO:0007194) regulation of adenylate cyclase activity(GO:0045761)
0.0 1.7 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 5.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 3.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.0 11.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 2.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0072299 visceral serous pericardium development(GO:0061032) negative regulation of glomerular mesangial cell proliferation(GO:0072125) posterior mesonephric tubule development(GO:0072166) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) regulation of metanephric glomerulus development(GO:0072298) negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194) negative regulation of cell proliferation involved in kidney development(GO:1901723)
0.0 1.4 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.0 GO:0034614 cellular response to reactive oxygen species(GO:0034614)
0.0 0.9 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0032804 viral protein processing(GO:0019082) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.8 GO:0014823 response to activity(GO:0014823)
0.0 1.0 GO:0070671 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.7 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:1901731 positive regulation of platelet aggregation(GO:1901731) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0 0.2 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.7 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.7 GO:0048477 oogenesis(GO:0048477)
0.0 0.1 GO:0021544 subpallium development(GO:0021544) striatum development(GO:0021756)
0.0 0.7 GO:0021549 cerebellum development(GO:0021549)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0036508 protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508)
0.0 0.9 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.8 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0071754 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
2.1 14.8 GO:0036021 endolysosome lumen(GO:0036021)
1.5 19.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.5 5.9 GO:0044307 dendritic branch(GO:0044307)
1.3 3.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.1 2.2 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.0 6.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.0 24.7 GO:0001891 phagocytic cup(GO:0001891)
0.9 17.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.9 52.8 GO:0001772 immunological synapse(GO:0001772)
0.9 2.6 GO:0031933 telomeric heterochromatin(GO:0031933)
0.8 4.7 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8 23.9 GO:0042101 T cell receptor complex(GO:0042101)
0.7 5.9 GO:0043596 nuclear replication fork(GO:0043596)
0.7 2.6 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.7 7.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 2.4 GO:0005602 complement component C1 complex(GO:0005602)
0.6 4.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.6 5.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5 2.7 GO:0089701 U2AF(GO:0089701)
0.5 5.5 GO:0060171 stereocilium membrane(GO:0060171)
0.5 0.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 16.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.4 6.8 GO:0045277 respiratory chain complex IV(GO:0045277)
0.4 15.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 2.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 3.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 5.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 2.0 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 4.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 4.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 4.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 14.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.0 GO:0060091 kinocilium(GO:0060091)
0.3 2.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 4.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 5.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 7.3 GO:0032982 myosin filament(GO:0032982)
0.3 2.8 GO:0005955 calcineurin complex(GO:0005955)
0.2 3.7 GO:0030914 STAGA complex(GO:0030914)
0.2 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.2 2.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 12.3 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 1.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 1.7 GO:0071953 elastic fiber(GO:0071953)
0.2 1.5 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 0.8 GO:0071546 pi-body(GO:0071546)
0.2 2.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.2 4.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 4.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:0002177 manchette(GO:0002177)
0.1 2.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 2.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 19.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.7 GO:0032437 cuticular plate(GO:0032437)
0.1 3.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.8 GO:0046930 pore complex(GO:0046930)
0.1 1.1 GO:0097452 GAIT complex(GO:0097452)
0.1 9.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 3.4 GO:0030057 desmosome(GO:0030057)
0.1 1.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 18.3 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.0 GO:0097440 apical dendrite(GO:0097440)
0.1 1.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 5.3 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 2.2 GO:0005682 U5 snRNP(GO:0005682)
0.1 6.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 2.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.5 GO:0043194 axon initial segment(GO:0043194)
0.1 4.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 6.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.9 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 11.5 GO:0072562 blood microparticle(GO:0072562)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 1.7 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.1 GO:0090544 BAF-type complex(GO:0090544)
0.1 2.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.5 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.8 GO:0031904 endosome lumen(GO:0031904)
0.1 80.3 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 3.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 13.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 6.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 6.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 3.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 1.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 21.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.4 7.3 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
2.4 7.1 GO:0005174 CD40 receptor binding(GO:0005174)
1.8 7.1 GO:0019770 IgG receptor activity(GO:0019770)
1.7 43.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.6 9.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.6 6.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.4 6.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.2 20.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.2 6.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.1 10.7 GO:0004064 arylesterase activity(GO:0004064)
1.0 6.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.9 4.6 GO:0019862 IgA binding(GO:0019862)
0.9 5.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.8 17.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 4.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.8 3.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.8 2.3 GO:0015616 DNA translocase activity(GO:0015616)
0.7 2.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 2.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.7 20.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.7 2.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.6 3.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.6 5.0 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.6 1.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.6 2.4 GO:0005148 prolactin receptor binding(GO:0005148)
0.6 3.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.6 4.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.6 1.7 GO:0032093 SAM domain binding(GO:0032093)
0.6 5.7 GO:0005549 odorant binding(GO:0005549)
0.6 6.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.5 5.9 GO:0036310 annealing helicase activity(GO:0036310)
0.5 5.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.5 2.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5 11.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.5 1.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.5 0.5 GO:0070052 collagen V binding(GO:0070052)
0.5 7.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 2.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5 2.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.5 2.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5 1.8 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.4 4.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4 13.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.4 4.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.4 1.3 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.4 1.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 5.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 2.9 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.4 1.6 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.4 2.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 2.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.4 77.0 GO:0003823 antigen binding(GO:0003823)
0.4 2.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 14.2 GO:0043236 laminin binding(GO:0043236)
0.4 4.9 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.4 1.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 2.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 1.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 1.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 10.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 5.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 0.6 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3 1.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 0.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 3.8 GO:0050700 CARD domain binding(GO:0050700)
0.3 4.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 20.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 8.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.3 0.9 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.3 1.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.3 1.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 5.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 1.0 GO:0002046 opsin binding(GO:0002046)
0.3 0.8 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 3.2 GO:0019841 retinol binding(GO:0019841)
0.2 3.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 0.7 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 0.7 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 0.7 GO:0004556 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 1.3 GO:0039552 RIG-I binding(GO:0039552)
0.2 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 2.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 7.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.6 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 1.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 0.8 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 5.0 GO:0048018 receptor agonist activity(GO:0048018)
0.2 0.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 5.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 6.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 17.5 GO:0005518 collagen binding(GO:0005518)
0.2 3.4 GO:0005522 profilin binding(GO:0005522)
0.2 2.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 4.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 2.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 2.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 4.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.9 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 2.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 3.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.6 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 2.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 5.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.9 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 3.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 3.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.5 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 3.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.4 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 37.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 4.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 5.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 2.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 10.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 4.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.7 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 12.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.0 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 1.0 GO:0001851 complement component C3b binding(GO:0001851)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.7 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 35.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 1.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.9 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.7 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.0 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 5.9 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 10.4 GO:0005179 hormone activity(GO:0005179)
0.1 5.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 1.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 1.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 1.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.8 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.1 2.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 2.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.2 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 1.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 7.1 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 16.0 GO:0051020 GTPase binding(GO:0051020)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.0 GO:0070697 activin receptor binding(GO:0070697)
0.0 2.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 3.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.6 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 6.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 10.8 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.6 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 7.3 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 1.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.4 41.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 25.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 17.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 21.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 15.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.3 13.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 4.9 PID IL3 PATHWAY IL3-mediated signaling events
0.2 1.5 ST STAT3 PATHWAY STAT3 Pathway
0.2 21.6 PID CMYB PATHWAY C-MYB transcription factor network
0.2 3.6 PID ARF 3PATHWAY Arf1 pathway
0.1 4.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 7.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 10.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 6.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 23.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.5 PID BMP PATHWAY BMP receptor signaling
0.1 2.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.8 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.3 PID TNF PATHWAY TNF receptor signaling pathway
0.1 7.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 5.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 14.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 3.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.2 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 12.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 6.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 14.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.9 22.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.7 10.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.7 16.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 20.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.5 92.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.5 12.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 6.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 9.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 8.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 1.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 3.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 13.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 2.2 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.3 1.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 5.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 3.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 6.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 4.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 5.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 14.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 4.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 5.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 5.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 2.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 13.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 7.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 9.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.1 REACTOME OPSINS Genes involved in Opsins
0.1 2.6 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 11.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 3.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 16.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 6.5 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.1 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.9 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 3.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.0 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 3.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation