Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for MXI1_MYC_MYCN
Z-value: 18.50
Motif logo
Transcription factors associated with MXI1_MYC_MYCN
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MXI1
|
ENSG00000119950.21 | MXI1 |
|
MYC
|
ENSG00000136997.21 | MYC |
|
MYCN
|
ENSG00000134323.12 | MYCN |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYC | hg38_v1_chr8_+_127737610_127737626, hg38_v1_chr8_+_127736220_127736241, hg38_v1_chr8_+_127735597_127735659, hg38_v1_chr8_+_127736046_127736084 | 0.80 | 1.1e-49 | Click! |
| MYCN | hg38_v1_chr2_+_15940537_15940566 | -0.59 | 3.7e-22 | Click! |
| MXI1 | hg38_v1_chr10_+_110207587_110207684, hg38_v1_chr10_+_110225955_110226016 | -0.36 | 4.0e-08 | Click! |
Activity profile of MXI1_MYC_MYCN motif
Sorted Z-values of MXI1_MYC_MYCN motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MXI1_MYC_MYCN
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 84.9 | 254.8 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 84.8 | 423.9 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 66.3 | 331.6 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 65.5 | 196.6 | GO:0002368 | B cell cytokine production(GO:0002368) |
| 59.7 | 239.0 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 53.0 | 318.1 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 52.1 | 521.0 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 46.6 | 139.8 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 44.7 | 402.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 41.1 | 287.4 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 40.3 | 161.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 35.9 | 107.6 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 35.5 | 177.3 | GO:0044209 | AMP salvage(GO:0044209) |
| 30.6 | 91.8 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 29.9 | 119.5 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 29.4 | 117.7 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 29.3 | 263.4 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 29.1 | 87.4 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 27.3 | 381.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 27.0 | 108.0 | GO:2000259 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 26.4 | 79.3 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
| 26.3 | 289.4 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 25.7 | 308.2 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 23.8 | 71.5 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 23.7 | 94.6 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 23.4 | 70.1 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 23.0 | 69.0 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 22.3 | 22.3 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 22.1 | 66.3 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 21.6 | 108.2 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 21.2 | 105.8 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 21.1 | 169.0 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 21.0 | 62.9 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 20.7 | 144.6 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 19.9 | 99.7 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 19.9 | 179.0 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 19.5 | 136.5 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 19.2 | 288.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 19.0 | 94.8 | GO:0006231 | dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073) |
| 18.8 | 93.8 | GO:0015862 | uridine transport(GO:0015862) |
| 18.2 | 54.5 | GO:1901389 | regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 18.0 | 36.1 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
| 17.8 | 71.3 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 17.5 | 52.5 | GO:0039689 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 16.2 | 48.7 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 16.1 | 96.8 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 15.3 | 107.1 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 15.3 | 45.8 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 15.2 | 75.9 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 15.1 | 60.5 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 14.9 | 59.4 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 14.6 | 131.7 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 14.6 | 58.3 | GO:2000426 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 14.4 | 43.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 14.3 | 42.8 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 14.2 | 42.5 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 13.8 | 41.5 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 13.8 | 41.3 | GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) |
| 13.8 | 123.9 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 13.6 | 54.3 | GO:1903751 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 13.5 | 40.6 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 13.5 | 40.6 | GO:1902905 | positive regulation of fibril organization(GO:1902905) |
| 13.2 | 13.2 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 13.1 | 39.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 12.9 | 64.3 | GO:0009213 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 12.5 | 125.4 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 12.5 | 12.5 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 12.4 | 74.3 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 12.3 | 12.3 | GO:0072048 | pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) |
| 12.3 | 49.3 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 12.2 | 36.5 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 12.0 | 72.1 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 11.8 | 35.5 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 11.8 | 153.6 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 11.7 | 164.4 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 11.6 | 127.1 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 11.4 | 159.8 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 11.3 | 22.5 | GO:0019322 | pentose biosynthetic process(GO:0019322) |
| 11.3 | 45.0 | GO:0051182 | coenzyme transport(GO:0051182) |
| 11.3 | 45.0 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 11.2 | 45.0 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 11.2 | 67.4 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 11.1 | 44.4 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 11.0 | 11.0 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 11.0 | 44.1 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 11.0 | 33.0 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 10.9 | 32.7 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 10.9 | 86.9 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 10.7 | 21.5 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 10.6 | 95.8 | GO:1902661 | positive regulation of glucose mediated signaling pathway(GO:1902661) |
| 10.5 | 10.5 | GO:1901355 | response to rapamycin(GO:1901355) |
| 10.3 | 133.7 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 10.3 | 30.8 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 10.2 | 81.4 | GO:0006561 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 10.0 | 59.9 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 9.8 | 78.4 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 9.8 | 29.3 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 9.6 | 134.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 9.5 | 28.6 | GO:0014876 | response to injury involved in regulation of muscle adaptation(GO:0014876) |
| 9.3 | 56.1 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 9.2 | 36.9 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 9.2 | 36.8 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 9.1 | 36.3 | GO:0048627 | myoblast development(GO:0048627) |
| 8.8 | 88.5 | GO:0045008 | depyrimidination(GO:0045008) |
| 8.8 | 43.9 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 8.7 | 26.1 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 8.6 | 25.7 | GO:1904387 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 8.5 | 34.1 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 8.5 | 42.5 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 8.4 | 101.1 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 8.4 | 100.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 8.2 | 57.2 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 8.1 | 97.7 | GO:0042407 | cristae formation(GO:0042407) |
| 8.1 | 73.2 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
| 8.0 | 64.3 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 7.8 | 23.5 | GO:1901874 | negative regulation of post-translational protein modification(GO:1901874) |
| 7.8 | 15.6 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 7.8 | 109.5 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 7.8 | 70.0 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 7.6 | 634.9 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 7.6 | 45.3 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 7.4 | 29.7 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 7.4 | 22.3 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 7.4 | 29.6 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 7.4 | 296.0 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 7.4 | 22.1 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 7.4 | 29.5 | GO:0043335 | protein unfolding(GO:0043335) |
| 7.2 | 14.3 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 7.1 | 64.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 7.1 | 28.3 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 7.0 | 42.2 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 7.0 | 28.0 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 7.0 | 21.0 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 7.0 | 34.8 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 6.9 | 55.4 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 6.9 | 20.6 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 6.8 | 20.5 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
| 6.8 | 13.6 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 6.7 | 26.9 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 6.7 | 13.4 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 6.6 | 26.5 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 6.6 | 26.3 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 6.6 | 52.5 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 6.5 | 98.2 | GO:0002190 | cap-independent translational initiation(GO:0002190) IRES-dependent translational initiation(GO:0002192) |
| 6.4 | 19.3 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 6.4 | 25.4 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 6.3 | 18.9 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 6.3 | 138.1 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 6.2 | 99.9 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 6.2 | 12.4 | GO:0019853 | L-ascorbic acid biosynthetic process(GO:0019853) |
| 6.1 | 18.4 | GO:0045554 | TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 6.1 | 18.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 6.1 | 30.4 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 6.0 | 24.1 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 6.0 | 18.0 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 6.0 | 18.0 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 6.0 | 17.9 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 6.0 | 11.9 | GO:1902822 | regulation of late endosome to lysosome transport(GO:1902822) |
| 5.9 | 35.2 | GO:0098704 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 5.9 | 105.6 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 5.8 | 5.8 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 5.8 | 116.7 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 5.8 | 23.3 | GO:0032262 | pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) |
| 5.8 | 11.6 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 5.8 | 17.3 | GO:2000174 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 5.8 | 17.3 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 5.7 | 34.4 | GO:1901836 | regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 5.7 | 22.9 | GO:0007144 | female meiosis I(GO:0007144) |
| 5.7 | 73.6 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 5.6 | 16.9 | GO:1904117 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 5.6 | 33.5 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 5.6 | 83.4 | GO:0000338 | protein deneddylation(GO:0000338) |
| 5.5 | 16.6 | GO:1903352 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
| 5.5 | 409.4 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 5.5 | 104.5 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 5.5 | 104.1 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 5.5 | 120.2 | GO:0098779 | mitophagy in response to mitochondrial depolarization(GO:0098779) |
| 5.4 | 27.2 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 5.4 | 32.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 5.4 | 10.8 | GO:0070842 | aggresome assembly(GO:0070842) |
| 5.4 | 124.0 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 5.4 | 43.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 5.4 | 262.4 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 5.3 | 26.6 | GO:0000012 | single strand break repair(GO:0000012) |
| 5.3 | 21.2 | GO:0009956 | radial pattern formation(GO:0009956) |
| 5.3 | 21.1 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 5.2 | 47.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 5.2 | 57.5 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 5.2 | 26.0 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 5.2 | 31.0 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 5.1 | 30.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 5.1 | 102.4 | GO:0000154 | rRNA modification(GO:0000154) |
| 5.1 | 15.3 | GO:0072019 | proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) |
| 5.1 | 5.1 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 5.1 | 66.0 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 5.1 | 45.5 | GO:0072553 | terminal button organization(GO:0072553) |
| 5.0 | 20.0 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 5.0 | 20.0 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 5.0 | 54.6 | GO:0042255 | ribosome assembly(GO:0042255) |
| 5.0 | 461.3 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) |
| 4.9 | 64.2 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 4.9 | 44.4 | GO:1900223 | positive regulation of beta-amyloid clearance(GO:1900223) |
| 4.9 | 14.8 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 4.9 | 39.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 4.9 | 92.7 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 4.8 | 29.1 | GO:0016128 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
| 4.8 | 53.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 4.8 | 33.9 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 4.8 | 14.4 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 4.8 | 33.7 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 4.8 | 24.0 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 4.8 | 23.8 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 4.7 | 94.7 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 4.7 | 23.6 | GO:0034398 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 4.7 | 42.5 | GO:0042262 | DNA protection(GO:0042262) |
| 4.7 | 4.7 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 4.7 | 18.8 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 4.7 | 37.3 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 4.7 | 18.6 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 4.7 | 116.4 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 4.7 | 14.0 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 4.7 | 27.9 | GO:0019060 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 4.6 | 23.2 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 4.6 | 64.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 4.6 | 9.2 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 4.6 | 27.5 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 4.6 | 82.2 | GO:0075713 | establishment of integrated proviral latency(GO:0075713) |
| 4.6 | 13.7 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 4.5 | 13.4 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 4.5 | 22.4 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 4.5 | 62.6 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 4.5 | 856.9 | GO:0006364 | rRNA processing(GO:0006364) |
| 4.4 | 17.7 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 4.3 | 4.3 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 4.3 | 17.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 4.3 | 21.5 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 4.3 | 12.8 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 4.2 | 33.9 | GO:0006265 | DNA topological change(GO:0006265) |
| 4.2 | 67.4 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 4.0 | 120.2 | GO:0015936 | coenzyme A metabolic process(GO:0015936) |
| 4.0 | 4.0 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 3.8 | 23.1 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 3.8 | 26.8 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 3.8 | 19.0 | GO:0009240 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490) |
| 3.8 | 18.9 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 3.7 | 3.7 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
| 3.7 | 11.2 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 3.7 | 11.1 | GO:0070272 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 3.7 | 84.9 | GO:0051031 | tRNA transport(GO:0051031) |
| 3.7 | 11.0 | GO:2000740 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 3.6 | 18.2 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 3.6 | 39.8 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 3.6 | 28.8 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 3.6 | 18.0 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 3.6 | 14.4 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 3.6 | 17.9 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 3.6 | 263.4 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 3.5 | 3.5 | GO:1904884 | establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 3.5 | 46.0 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 3.5 | 13.9 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 3.5 | 41.6 | GO:0010918 | positive regulation of mitochondrial membrane potential(GO:0010918) |
| 3.5 | 17.3 | GO:0048539 | bone marrow development(GO:0048539) |
| 3.5 | 17.3 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 3.4 | 13.7 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 3.4 | 23.9 | GO:0030421 | defecation(GO:0030421) |
| 3.4 | 33.9 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 3.4 | 23.6 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 3.4 | 16.9 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 3.4 | 23.6 | GO:0032218 | riboflavin transport(GO:0032218) |
| 3.4 | 47.1 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 3.3 | 93.3 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 3.3 | 56.0 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 3.3 | 42.5 | GO:0032310 | prostaglandin secretion(GO:0032310) |
| 3.2 | 9.7 | GO:0061017 | hepatic duct development(GO:0061011) hepatoblast differentiation(GO:0061017) |
| 3.2 | 16.1 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 3.2 | 6.4 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 3.2 | 9.5 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 3.2 | 9.5 | GO:0009120 | deoxyribonucleoside metabolic process(GO:0009120) deoxyribonucleoside catabolic process(GO:0046121) |
| 3.1 | 18.9 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 3.1 | 12.6 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 3.1 | 72.1 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 3.1 | 12.5 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 3.1 | 33.8 | GO:1903944 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 3.0 | 12.1 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 3.0 | 11.9 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 3.0 | 8.9 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 3.0 | 3.0 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 2.9 | 5.9 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 2.9 | 14.7 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 2.9 | 8.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 2.9 | 17.2 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 2.8 | 48.0 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 2.8 | 8.4 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 2.8 | 28.0 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 2.8 | 27.9 | GO:0051451 | myoblast migration(GO:0051451) |
| 2.8 | 8.3 | GO:1904897 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 2.8 | 5.5 | GO:1903721 | regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 2.7 | 33.0 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 2.7 | 16.0 | GO:0043248 | proteasome assembly(GO:0043248) |
| 2.6 | 7.9 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 2.6 | 39.5 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 2.6 | 28.9 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 2.6 | 18.2 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
| 2.6 | 38.8 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 2.6 | 46.4 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 2.6 | 33.4 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 2.5 | 32.9 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 2.5 | 20.2 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 2.5 | 7.5 | GO:0097032 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 2.5 | 15.0 | GO:0070836 | caveola assembly(GO:0070836) |
| 2.4 | 31.6 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 2.4 | 7.3 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 2.4 | 12.1 | GO:0060613 | fat pad development(GO:0060613) |
| 2.4 | 9.5 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 2.4 | 97.6 | GO:0043486 | histone exchange(GO:0043486) |
| 2.4 | 19.0 | GO:0044351 | macropinocytosis(GO:0044351) |
| 2.4 | 26.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 2.4 | 7.1 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 2.4 | 28.4 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 2.4 | 2.4 | GO:1904429 | regulation of t-circle formation(GO:1904429) positive regulation of t-circle formation(GO:1904431) |
| 2.4 | 9.4 | GO:0015911 | plasma membrane long-chain fatty acid transport(GO:0015911) |
| 2.4 | 7.1 | GO:0042704 | uterine wall breakdown(GO:0042704) |
| 2.4 | 14.1 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 2.4 | 4.7 | GO:0040031 | snRNA modification(GO:0040031) |
| 2.4 | 11.8 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 2.3 | 21.0 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 2.3 | 9.3 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 2.3 | 9.2 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 2.3 | 13.9 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 2.3 | 4.5 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 2.3 | 9.1 | GO:0032599 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 2.3 | 9.0 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 2.3 | 6.8 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 2.2 | 4.5 | GO:0031393 | negative regulation of prostaglandin biosynthetic process(GO:0031393) |
| 2.2 | 4.5 | GO:0006550 | isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550) |
| 2.1 | 6.4 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 2.1 | 145.0 | GO:0070671 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
| 2.1 | 6.3 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 2.1 | 10.5 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 2.1 | 8.4 | GO:0045002 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002) |
| 2.1 | 8.4 | GO:0046543 | thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744) |
| 2.1 | 8.4 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 2.1 | 52.0 | GO:0097341 | inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) |
| 2.1 | 59.9 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 2.1 | 26.8 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 2.0 | 10.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 2.0 | 10.2 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 2.0 | 26.1 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 2.0 | 25.7 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 2.0 | 11.8 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 2.0 | 2.0 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 2.0 | 55.1 | GO:0075733 | intracellular transport of virus(GO:0075733) |
| 2.0 | 7.8 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 1.9 | 7.7 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 1.9 | 7.7 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 1.9 | 24.9 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 1.9 | 9.6 | GO:0048143 | astrocyte activation(GO:0048143) |
| 1.9 | 5.7 | GO:0036233 | glycine import(GO:0036233) |
| 1.9 | 5.7 | GO:0060739 | bud outgrowth involved in lung branching(GO:0060447) mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739) |
| 1.9 | 1.9 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 1.9 | 5.7 | GO:2000491 | regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491) |
| 1.9 | 11.3 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 1.9 | 1.9 | GO:1990791 | dorsal root ganglion development(GO:1990791) |
| 1.9 | 5.6 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 1.9 | 16.9 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 1.9 | 26.2 | GO:1903753 | negative regulation of p38MAPK cascade(GO:1903753) |
| 1.9 | 14.9 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 1.9 | 7.4 | GO:0070071 | proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 1.8 | 7.2 | GO:0061146 | mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) |
| 1.8 | 7.2 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 1.8 | 9.0 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) |
| 1.8 | 23.4 | GO:0030656 | regulation of vitamin metabolic process(GO:0030656) |
| 1.8 | 23.2 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 1.8 | 10.6 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 1.8 | 53.2 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 1.8 | 10.5 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 1.7 | 3.5 | GO:0090035 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 1.7 | 7.0 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 1.7 | 57.3 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 1.7 | 10.3 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 1.7 | 6.8 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 1.7 | 8.5 | GO:0031585 | regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) |
| 1.7 | 13.4 | GO:0007379 | segment specification(GO:0007379) |
| 1.7 | 40.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 1.7 | 49.9 | GO:1901998 | toxin transport(GO:1901998) |
| 1.7 | 8.3 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.7 | 5.0 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 1.6 | 18.1 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 1.6 | 4.9 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 1.6 | 3.3 | GO:0070103 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) |
| 1.6 | 11.4 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 1.6 | 11.3 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 1.6 | 8.0 | GO:0003149 | membranous septum morphogenesis(GO:0003149) |
| 1.6 | 14.3 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 1.6 | 4.7 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 1.6 | 43.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 1.6 | 7.8 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 1.6 | 6.2 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 1.6 | 17.1 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 1.5 | 4.6 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 1.5 | 15.5 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 1.5 | 1.5 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 1.5 | 9.3 | GO:0031337 | cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668) |
| 1.5 | 94.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 1.5 | 52.0 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 1.5 | 67.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 1.5 | 8.9 | GO:0031947 | negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) |
| 1.4 | 20.3 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 1.4 | 15.3 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 1.4 | 6.9 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 1.4 | 16.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 1.4 | 38.0 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 1.3 | 4.0 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 1.3 | 5.3 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 1.3 | 15.9 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 1.3 | 5.3 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 1.3 | 5.2 | GO:0034344 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 1.3 | 18.1 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 1.3 | 10.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 1.3 | 7.6 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 1.3 | 22.6 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 1.2 | 11.2 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 1.2 | 11.0 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 1.2 | 10.9 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 1.2 | 3.6 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 1.2 | 111.1 | GO:0001909 | leukocyte mediated cytotoxicity(GO:0001909) |
| 1.2 | 9.5 | GO:0018202 | peptidyl-histidine modification(GO:0018202) |
| 1.2 | 10.6 | GO:0042747 | circadian sleep/wake cycle, REM sleep(GO:0042747) |
| 1.2 | 12.8 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 1.2 | 4.6 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
| 1.2 | 2.3 | GO:1900020 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 1.2 | 1.2 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
| 1.2 | 16.1 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 1.2 | 17.3 | GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) |
| 1.1 | 9.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 1.1 | 34.0 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 1.1 | 2.3 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 1.1 | 10.2 | GO:0002934 | desmosome organization(GO:0002934) |
| 1.1 | 18.0 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 1.1 | 4.5 | GO:0051013 | microtubule severing(GO:0051013) |
| 1.1 | 2.2 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 1.1 | 3.4 | GO:1903421 | regulation of synaptic vesicle recycling(GO:1903421) |
| 1.1 | 9.9 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 1.1 | 5.5 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 1.1 | 9.8 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 1.1 | 13.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 1.1 | 1.1 | GO:0014734 | skeletal muscle hypertrophy(GO:0014734) |
| 1.1 | 8.6 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 1.1 | 15.0 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 1.1 | 18.2 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 1.1 | 84.3 | GO:0048208 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 1.1 | 8.5 | GO:0002759 | regulation of antimicrobial humoral response(GO:0002759) |
| 1.1 | 6.3 | GO:0015853 | adenine transport(GO:0015853) |
| 1.0 | 3.1 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 1.0 | 4.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 1.0 | 2.0 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 1.0 | 6.1 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 1.0 | 11.1 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 1.0 | 6.0 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 1.0 | 5.0 | GO:0042374 | phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662) |
| 1.0 | 6.0 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 1.0 | 5.9 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 1.0 | 45.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 1.0 | 23.4 | GO:0051923 | sulfation(GO:0051923) |
| 1.0 | 17.5 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 1.0 | 22.3 | GO:0030033 | microvillus assembly(GO:0030033) |
| 1.0 | 5.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 1.0 | 2.9 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 1.0 | 17.2 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.9 | 10.4 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.9 | 59.4 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.9 | 17.9 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.9 | 7.5 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.9 | 9.3 | GO:0021603 | cranial nerve formation(GO:0021603) |
| 0.9 | 4.6 | GO:1901202 | negative regulation of extracellular matrix assembly(GO:1901202) |
| 0.9 | 4.6 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.9 | 4.6 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.9 | 7.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.9 | 8.2 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.9 | 5.4 | GO:0051958 | methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838) |
| 0.9 | 26.2 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.9 | 6.3 | GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) |
| 0.9 | 5.4 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 0.9 | 4.4 | GO:0001777 | T cell homeostatic proliferation(GO:0001777) |
| 0.9 | 16.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.9 | 12.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.9 | 1.7 | GO:0014806 | smooth muscle adaptation(GO:0014805) smooth muscle hyperplasia(GO:0014806) |
| 0.9 | 2.6 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.9 | 9.4 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.8 | 22.1 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.8 | 2.5 | GO:0009223 | pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.8 | 5.1 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.8 | 5.9 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.8 | 69.8 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.8 | 11.7 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.8 | 2.5 | GO:1990834 | response to odorant(GO:1990834) |
| 0.8 | 11.4 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.8 | 4.1 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.8 | 5.7 | GO:0032328 | alanine transport(GO:0032328) |
| 0.8 | 8.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.8 | 7.3 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.8 | 13.8 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.8 | 16.0 | GO:0008228 | opsonization(GO:0008228) |
| 0.8 | 7.2 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.8 | 5.6 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.8 | 4.0 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.8 | 3.1 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.8 | 10.1 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.8 | 3.9 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.8 | 31.7 | GO:0050850 | positive regulation of calcium-mediated signaling(GO:0050850) |
| 0.8 | 6.9 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.8 | 12.8 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.7 | 8.9 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.7 | 0.7 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.7 | 16.6 | GO:0097502 | mannosylation(GO:0097502) |
| 0.7 | 9.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.7 | 41.5 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.7 | 5.7 | GO:0042534 | tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534) |
| 0.7 | 9.2 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.7 | 0.7 | GO:0034163 | regulation of toll-like receptor 9 signaling pathway(GO:0034163) |
| 0.7 | 2.8 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 0.7 | 3.4 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 0.7 | 4.0 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.7 | 8.7 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.7 | 10.0 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.7 | 3.3 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.7 | 15.2 | GO:0061621 | NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.6 | 4.5 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.6 | 9.7 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.6 | 3.1 | GO:0035989 | tendon development(GO:0035989) |
| 0.6 | 2.5 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.6 | 1.9 | GO:0001821 | histamine secretion(GO:0001821) histamine transport(GO:0051608) |
| 0.6 | 41.5 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.6 | 1.8 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 0.6 | 1.2 | GO:0048199 | vesicle targeting, to, from or within Golgi(GO:0048199) |
| 0.6 | 1.8 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.6 | 4.5 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.6 | 5.5 | GO:0046149 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.6 | 13.8 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.5 | 6.5 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.5 | 5.4 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.5 | 2.1 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.5 | 25.1 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.5 | 1.0 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.5 | 20.3 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.5 | 2.1 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.5 | 11.5 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.5 | 5.7 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.5 | 4.2 | GO:1904754 | positive regulation of vascular associated smooth muscle cell migration(GO:1904754) |
| 0.5 | 22.3 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.5 | 5.7 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.5 | 19.6 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.5 | 4.1 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.5 | 4.0 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.5 | 3.0 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.5 | 7.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.5 | 22.6 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
| 0.5 | 5.3 | GO:0071732 | response to nitric oxide(GO:0071731) cellular response to nitric oxide(GO:0071732) |
| 0.5 | 3.3 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.5 | 10.0 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.5 | 1.4 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.5 | 1.9 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.5 | 16.5 | GO:0019079 | viral genome replication(GO:0019079) |
| 0.5 | 0.5 | GO:0032423 | regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425) |
| 0.5 | 1.4 | GO:2000847 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.5 | 1.8 | GO:0071316 | cellular response to nicotine(GO:0071316) |
| 0.4 | 0.9 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.4 | 0.9 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 0.4 | 2.2 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.4 | 11.3 | GO:0006101 | tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101) |
| 0.4 | 10.9 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.4 | 22.8 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.4 | 3.9 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 0.4 | 8.5 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.4 | 3.0 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.4 | 1.7 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.4 | 3.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.4 | 0.4 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.4 | 2.5 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.4 | 1.2 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.4 | 10.5 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
| 0.4 | 34.2 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.4 | 3.9 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.4 | 2.3 | GO:0033591 | response to L-ascorbic acid(GO:0033591) positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.4 | 8.0 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
| 0.4 | 4.9 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.4 | 2.6 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.4 | 1.4 | GO:0090656 | t-circle formation(GO:0090656) |
| 0.4 | 11.7 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.4 | 2.5 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.3 | 8.3 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.3 | 1.7 | GO:0090009 | primitive streak formation(GO:0090009) |
| 0.3 | 3.0 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.3 | 3.7 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.3 | 5.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.3 | 14.1 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.3 | 0.9 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.3 | 0.9 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.3 | 1.3 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.3 | 5.3 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.3 | 2.8 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.3 | 2.2 | GO:0033683 | nucleotide-excision repair, DNA incision(GO:0033683) |
| 0.3 | 0.6 | GO:0008356 | asymmetric cell division(GO:0008356) |
| 0.3 | 10.0 | GO:0030838 | positive regulation of actin filament polymerization(GO:0030838) |
| 0.3 | 1.2 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.3 | 14.7 | GO:0007569 | cell aging(GO:0007569) |
| 0.3 | 7.9 | GO:0072662 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.3 | 3.8 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.3 | 1.2 | GO:0019376 | galactolipid catabolic process(GO:0019376) |
| 0.3 | 5.5 | GO:0036344 | platelet morphogenesis(GO:0036344) |
| 0.3 | 2.0 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.3 | 1.6 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 2.9 | GO:0045076 | regulation of interleukin-2 biosynthetic process(GO:0045076) positive regulation of interleukin-2 biosynthetic process(GO:0045086) |
| 0.3 | 5.0 | GO:0017145 | stem cell division(GO:0017145) |
| 0.3 | 1.3 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.3 | 1.3 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.3 | 2.0 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.2 | 8.9 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
| 0.2 | 2.0 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.2 | 1.5 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.2 | 5.6 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.2 | 2.9 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.2 | 9.8 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.2 | 1.6 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.2 | 0.7 | GO:0045605 | negative regulation of epidermal cell differentiation(GO:0045605) |
| 0.2 | 2.0 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.2 | 1.6 | GO:1904886 | beta-catenin destruction complex disassembly(GO:1904886) |
| 0.2 | 2.2 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.2 | 1.1 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.2 | 2.4 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.2 | 9.1 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.2 | 1.3 | GO:0060356 | leucine import(GO:0060356) |
| 0.2 | 2.1 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.2 | 1.0 | GO:0051444 | negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
| 0.2 | 1.0 | GO:0060581 | ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) |
| 0.2 | 1.4 | GO:0060444 | branching involved in mammary gland duct morphogenesis(GO:0060444) |
| 0.2 | 2.6 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.2 | 0.6 | GO:0036363 | transforming growth factor beta activation(GO:0036363) |
| 0.2 | 3.5 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.2 | 0.6 | GO:0015732 | prostaglandin transport(GO:0015732) |
| 0.2 | 0.9 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.2 | 1.1 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.5 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.2 | 1.1 | GO:0042026 | protein refolding(GO:0042026) |
| 0.2 | 2.0 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.2 | 1.0 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.2 | 4.0 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.2 | 5.6 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.2 | 0.5 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.2 | 5.1 | GO:0031100 | organ regeneration(GO:0031100) |
| 0.1 | 1.8 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 1.0 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.1 | 0.7 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 2.1 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.1 | 1.2 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 0.5 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.1 | 3.6 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
| 0.1 | 1.5 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.1 | 1.6 | GO:0097435 | fibril organization(GO:0097435) |
| 0.1 | 0.9 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.1 | 0.4 | GO:0071888 | macrophage apoptotic process(GO:0071888) |
| 0.1 | 1.9 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.1 | 1.6 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.1 | 0.3 | GO:0033688 | regulation of osteoblast proliferation(GO:0033688) |
| 0.1 | 1.6 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 0.4 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 0.1 | 0.8 | GO:1901750 | glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.1 | 0.5 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
| 0.1 | 0.4 | GO:0050893 | sensory processing(GO:0050893) |
| 0.1 | 0.1 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.1 | 1.6 | GO:0032801 | receptor catabolic process(GO:0032801) |
| 0.1 | 0.6 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.1 | 0.5 | GO:0061430 | bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) |
| 0.1 | 0.6 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 0.5 | GO:0006553 | lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554) |
| 0.1 | 1.0 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 0.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.1 | 0.6 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.1 | 0.3 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.0 | 1.2 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.0 | 0.2 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
| 0.0 | 6.6 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.5 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.1 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.0 | 0.7 | GO:0071479 | cellular response to ionizing radiation(GO:0071479) |
| 0.0 | 0.4 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.0 | 0.5 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.0 | 0.2 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.0 | 0.0 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.0 | 0.7 | GO:0090175 | Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175) |
| 0.0 | 0.2 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.1 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.0 | 0.1 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.0 | 0.1 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.0 | 0.1 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.0 | 0.1 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 69.7 | 418.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 46.5 | 279.0 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 37.7 | 302.0 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 33.6 | 100.8 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 32.4 | 227.1 | GO:0090661 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 31.9 | 127.7 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 31.3 | 344.2 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 28.5 | 284.9 | GO:0070552 | BRISC complex(GO:0070552) |
| 27.6 | 248.1 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 27.1 | 135.7 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 24.4 | 146.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 24.4 | 365.5 | GO:0034709 | methylosome(GO:0034709) |
| 22.7 | 90.9 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 19.7 | 157.5 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 18.7 | 130.8 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 18.6 | 130.0 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 18.2 | 54.5 | GO:1990913 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 18.0 | 126.0 | GO:0031415 | NatA complex(GO:0031415) |
| 15.3 | 91.9 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 14.4 | 143.8 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 13.4 | 80.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 12.9 | 90.0 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 12.2 | 231.9 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 12.2 | 194.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 11.9 | 35.8 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 11.9 | 59.4 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 11.8 | 389.2 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 11.7 | 81.6 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 10.9 | 43.6 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 10.8 | 108.1 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 10.5 | 105.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 10.5 | 52.5 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 9.7 | 116.5 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 9.5 | 38.1 | GO:0071986 | Ragulator complex(GO:0071986) |
| 9.5 | 47.3 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 9.3 | 270.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 9.1 | 109.5 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 8.8 | 88.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 8.6 | 43.0 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 8.6 | 25.7 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 8.1 | 73.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 8.1 | 65.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 8.1 | 145.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 8.1 | 24.2 | GO:0005745 | m-AAA complex(GO:0005745) |
| 7.9 | 87.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 7.9 | 79.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 7.9 | 102.1 | GO:0042555 | MCM complex(GO:0042555) |
| 7.8 | 372.0 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 7.7 | 38.6 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 7.6 | 137.0 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 7.1 | 28.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 7.0 | 21.0 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 7.0 | 27.9 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 7.0 | 20.9 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 6.8 | 27.2 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 6.7 | 60.7 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 6.4 | 250.2 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 6.3 | 88.5 | GO:0090543 | Flemming body(GO:0090543) |
| 6.3 | 94.8 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 6.3 | 81.6 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 6.2 | 50.0 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 6.2 | 25.0 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 6.1 | 30.4 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 6.1 | 242.1 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 6.0 | 12.0 | GO:0071817 | MMXD complex(GO:0071817) |
| 5.9 | 23.6 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 5.9 | 11.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 5.8 | 52.0 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 5.8 | 23.0 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 5.6 | 39.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 5.6 | 39.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 5.5 | 77.1 | GO:0005686 | U2 snRNP(GO:0005686) |
| 5.5 | 71.3 | GO:0005688 | U6 snRNP(GO:0005688) |
| 5.5 | 82.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 5.3 | 42.6 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 5.3 | 26.5 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 5.2 | 21.0 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 5.1 | 106.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 5.0 | 55.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 5.0 | 14.9 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 5.0 | 44.8 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 4.9 | 44.3 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 4.7 | 14.1 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 4.7 | 42.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 4.7 | 167.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 4.6 | 64.8 | GO:0030686 | 90S preribosome(GO:0030686) |
| 4.6 | 468.8 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 4.6 | 13.7 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 4.5 | 59.0 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 4.5 | 13.6 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 4.5 | 22.5 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 4.4 | 35.0 | GO:0097255 | R2TP complex(GO:0097255) |
| 4.4 | 30.6 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 4.3 | 47.2 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 4.3 | 12.8 | GO:0044393 | microspike(GO:0044393) |
| 4.3 | 34.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 4.1 | 24.5 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 4.0 | 52.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 4.0 | 31.9 | GO:0031931 | TORC1 complex(GO:0031931) |
| 3.9 | 15.6 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 3.9 | 15.6 | GO:0071942 | XPC complex(GO:0071942) |
| 3.8 | 19.2 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 3.8 | 37.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 3.7 | 33.7 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 3.7 | 11.2 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 3.7 | 44.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 3.7 | 14.8 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 3.7 | 11.0 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 3.7 | 18.3 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 3.6 | 10.9 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 3.6 | 3.6 | GO:0071920 | cleavage body(GO:0071920) |
| 3.6 | 97.4 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 3.6 | 10.7 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 3.6 | 17.9 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 3.5 | 326.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 3.5 | 63.0 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 3.5 | 41.7 | GO:0032040 | small-subunit processome(GO:0032040) |
| 3.5 | 41.6 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 3.4 | 44.1 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 3.4 | 13.4 | GO:0022624 | proteasome accessory complex(GO:0022624) |
| 3.3 | 19.6 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 3.2 | 64.9 | GO:0016469 | proton-transporting two-sector ATPase complex(GO:0016469) |
| 3.2 | 16.0 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 3.2 | 580.5 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 3.1 | 52.8 | GO:0032433 | filopodium tip(GO:0032433) |
| 3.0 | 333.6 | GO:0005840 | ribosome(GO:0005840) |
| 2.9 | 11.6 | GO:0035841 | new growing cell tip(GO:0035841) |
| 2.9 | 197.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 2.9 | 31.8 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 2.9 | 31.8 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 2.9 | 23.0 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 2.8 | 59.2 | GO:0071437 | invadopodium(GO:0071437) |
| 2.8 | 13.9 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 2.7 | 16.3 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 2.7 | 5.4 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 2.7 | 115.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 2.6 | 26.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 2.6 | 33.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 2.6 | 7.7 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 2.5 | 38.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 2.5 | 17.7 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 2.5 | 14.9 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 2.5 | 17.3 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 2.5 | 4.9 | GO:0055087 | Ski complex(GO:0055087) |
| 2.4 | 26.5 | GO:0097470 | ribbon synapse(GO:0097470) |
| 2.4 | 4.8 | GO:0030681 | multimeric ribonuclease P complex(GO:0030681) |
| 2.4 | 7.1 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 2.4 | 532.6 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 2.3 | 39.7 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 2.3 | 2.3 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 2.3 | 36.6 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 2.3 | 38.4 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 2.2 | 315.6 | GO:0016605 | PML body(GO:0016605) |
| 2.2 | 6.5 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 2.1 | 12.8 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 2.1 | 22.9 | GO:0005685 | U1 snRNP(GO:0005685) |
| 2.1 | 18.7 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 2.1 | 10.3 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 2.0 | 22.4 | GO:0097413 | Lewy body(GO:0097413) |
| 2.0 | 67.0 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 2.0 | 163.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 2.0 | 68.4 | GO:0031941 | filamentous actin(GO:0031941) |
| 1.9 | 88.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 1.9 | 5.6 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 1.9 | 74.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 1.9 | 24.3 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 1.9 | 20.5 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 1.9 | 1.9 | GO:0035061 | interchromatin granule(GO:0035061) |
| 1.8 | 224.0 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.8 | 8.8 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 1.7 | 6.8 | GO:0005682 | U5 snRNP(GO:0005682) |
| 1.7 | 107.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 1.7 | 20.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 1.7 | 5.0 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 1.6 | 18.0 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 1.6 | 3.3 | GO:0030120 | vesicle coat(GO:0030120) clathrin vesicle coat(GO:0030125) |
| 1.6 | 4.9 | GO:0030684 | preribosome(GO:0030684) |
| 1.6 | 27.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 1.6 | 31.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 1.6 | 6.2 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 1.5 | 4.6 | GO:0001939 | female pronucleus(GO:0001939) |
| 1.5 | 3.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 1.5 | 4.5 | GO:0034657 | GID complex(GO:0034657) |
| 1.5 | 7.4 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 1.5 | 10.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 1.4 | 59.7 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 1.4 | 19.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 1.4 | 8.4 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 1.3 | 34.9 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 1.3 | 12.0 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 1.3 | 185.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 1.3 | 93.5 | GO:0005811 | lipid particle(GO:0005811) |
| 1.3 | 78.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 1.3 | 3.9 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 1.3 | 16.9 | GO:0016600 | flotillin complex(GO:0016600) |
| 1.3 | 29.1 | GO:0000502 | proteasome complex(GO:0000502) |
| 1.3 | 10.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 1.2 | 104.2 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 1.2 | 23.9 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 1.2 | 5.9 | GO:0030056 | hemidesmosome(GO:0030056) |
| 1.2 | 15.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 1.1 | 4.5 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.1 | 18.7 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 1.1 | 5.4 | GO:0089701 | U2AF(GO:0089701) |
| 1.1 | 4.3 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 1.1 | 2.1 | GO:0098576 | lumenal side of membrane(GO:0098576) |
| 1.0 | 6.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 1.0 | 3.1 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 1.0 | 9.3 | GO:0070449 | elongin complex(GO:0070449) |
| 1.0 | 2.0 | GO:0032426 | stereocilium tip(GO:0032426) |
| 1.0 | 7.8 | GO:0097443 | sorting endosome(GO:0097443) |
| 1.0 | 23.5 | GO:0097228 | sperm principal piece(GO:0097228) |
| 1.0 | 4.8 | GO:0001739 | sex chromatin(GO:0001739) |
| 1.0 | 77.1 | GO:0070469 | respiratory chain(GO:0070469) |
| 1.0 | 2.9 | GO:0044754 | autolysosome(GO:0044754) |
| 0.9 | 28.5 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.9 | 122.3 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.9 | 53.3 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.9 | 8.1 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.9 | 2522.9 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.9 | 4.3 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.8 | 42.2 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.8 | 16.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.8 | 3.9 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.8 | 42.0 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.8 | 8.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.8 | 9.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.8 | 4.5 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.7 | 28.5 | GO:0043034 | costamere(GO:0043034) |
| 0.7 | 15.8 | GO:0005903 | brush border(GO:0005903) |
| 0.7 | 5.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.7 | 2.0 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.7 | 127.3 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.6 | 15.9 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.6 | 7.0 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.6 | 1.9 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.6 | 458.5 | GO:0005730 | nucleolus(GO:0005730) |
| 0.6 | 39.9 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.6 | 11.9 | GO:0002102 | podosome(GO:0002102) |
| 0.6 | 3.4 | GO:0030904 | retromer complex(GO:0030904) |
| 0.6 | 6.1 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.6 | 3.9 | GO:0032021 | NELF complex(GO:0032021) |
| 0.5 | 26.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.5 | 2.4 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.5 | 3.7 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 4.0 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.4 | 23.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.4 | 4.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.3 | 24.6 | GO:0030018 | Z disc(GO:0030018) |
| 0.3 | 11.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.3 | 0.8 | GO:0005600 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.3 | 7.2 | GO:0042641 | actomyosin(GO:0042641) |
| 0.2 | 7.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.2 | 2.5 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.2 | 5.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.2 | 1.0 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.2 | 0.7 | GO:0097346 | INO80-type complex(GO:0097346) |
| 0.2 | 0.9 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.2 | 2.3 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.2 | 2.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 0.7 | GO:0071203 | WASH complex(GO:0071203) |
| 0.2 | 33.0 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 4.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 1.5 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 4.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 2.4 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 5.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 2.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 1.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 1.6 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 0.4 | GO:0000938 | GARP complex(GO:0000938) |
| 0.0 | 0.1 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.0 | 0.3 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.5 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.1 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 94.3 | 282.8 | GO:0004638 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 63.7 | 254.8 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 53.0 | 318.1 | GO:0004372 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 47.9 | 287.4 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 46.6 | 139.8 | GO:0070364 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 46.2 | 138.7 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 45.5 | 136.5 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 38.7 | 232.5 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 37.7 | 302.0 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 34.0 | 203.8 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 33.3 | 133.0 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 32.4 | 227.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 31.6 | 94.8 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 31.5 | 94.6 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 31.1 | 249.0 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 30.6 | 91.8 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 30.0 | 90.0 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 27.8 | 111.0 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 27.4 | 521.4 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 25.4 | 127.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 24.4 | 97.7 | GO:0031177 | phosphopantetheine binding(GO:0031177) |
| 21.6 | 64.9 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 21.1 | 105.7 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 20.2 | 80.9 | GO:0097506 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 18.9 | 94.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 18.6 | 74.4 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 18.2 | 54.5 | GO:0002135 | CTP binding(GO:0002135) |
| 18.1 | 126.9 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 17.0 | 51.0 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 16.8 | 234.8 | GO:0031386 | protein tag(GO:0031386) |
| 16.6 | 83.0 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 15.9 | 111.5 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 15.8 | 63.4 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 15.1 | 166.5 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 14.9 | 59.4 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 14.8 | 59.1 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 14.6 | 117.1 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 14.5 | 72.3 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 14.4 | 43.2 | GO:0034512 | box C/D snoRNA binding(GO:0034512) |
| 14.2 | 555.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 13.8 | 41.5 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 13.6 | 54.5 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 13.1 | 13.1 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 13.0 | 91.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 12.7 | 25.4 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 12.6 | 101.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 12.2 | 194.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 12.0 | 36.1 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 11.7 | 105.3 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 11.4 | 57.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 11.3 | 56.7 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 11.3 | 33.9 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 11.1 | 44.2 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 11.0 | 44.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 10.9 | 391.8 | GO:0008143 | poly(A) binding(GO:0008143) |
| 10.9 | 86.9 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 10.8 | 32.4 | GO:0047693 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 10.5 | 73.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 10.4 | 41.6 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 10.3 | 30.8 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 10.1 | 182.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 10.1 | 40.3 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 9.9 | 49.7 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 9.9 | 276.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 9.8 | 88.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 9.8 | 58.5 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 9.4 | 112.9 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 9.2 | 45.8 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 9.1 | 27.2 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 9.1 | 54.5 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 9.1 | 99.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 9.0 | 35.9 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 8.9 | 44.6 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 8.8 | 26.5 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 8.7 | 17.4 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 8.6 | 60.2 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 8.6 | 25.7 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 8.5 | 59.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 8.5 | 68.1 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 8.3 | 58.3 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 8.3 | 41.5 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 8.3 | 90.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 8.3 | 41.3 | GO:0008469 | histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 8.3 | 33.0 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 8.2 | 65.6 | GO:0015288 | porin activity(GO:0015288) |
| 8.2 | 114.6 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 8.1 | 24.2 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 8.0 | 24.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 8.0 | 119.9 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 7.8 | 382.2 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 7.8 | 23.4 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 7.7 | 362.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 7.6 | 30.4 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 7.5 | 7.5 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 7.5 | 45.1 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 7.5 | 60.0 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 7.5 | 37.3 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 7.4 | 22.3 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 7.4 | 14.8 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 7.3 | 14.7 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 7.3 | 22.0 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 7.2 | 173.5 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 7.1 | 56.4 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 6.9 | 55.5 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 6.9 | 34.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 6.9 | 20.6 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
| 6.8 | 190.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 6.7 | 40.3 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 6.5 | 300.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 6.5 | 51.8 | GO:0032552 | deoxyribonucleotide binding(GO:0032552) |
| 6.5 | 109.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 6.4 | 38.6 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 6.4 | 19.1 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 6.3 | 114.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 6.3 | 63.4 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 6.3 | 31.6 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 6.2 | 111.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 6.0 | 24.1 | GO:0042282 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 6.0 | 24.1 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 5.9 | 395.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 5.9 | 35.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 5.9 | 35.2 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 5.8 | 23.3 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 5.8 | 17.3 | GO:0016936 | galactoside binding(GO:0016936) |
| 5.7 | 195.1 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 5.7 | 45.9 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 5.7 | 34.3 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 5.7 | 56.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 5.7 | 22.7 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 5.6 | 33.7 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 5.6 | 22.3 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 5.5 | 16.6 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 5.5 | 5.5 | GO:0032551 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 5.5 | 256.8 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 5.3 | 42.6 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 5.3 | 53.0 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 5.2 | 20.8 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 5.1 | 10.3 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 5.1 | 262.1 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 5.0 | 15.1 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 5.0 | 100.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 4.9 | 54.4 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 4.8 | 29.1 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 4.8 | 19.3 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 4.8 | 23.9 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 4.7 | 47.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 4.7 | 14.2 | GO:0000248 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 4.7 | 42.3 | GO:0089720 | caspase binding(GO:0089720) |
| 4.7 | 70.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 4.7 | 37.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 4.6 | 36.9 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 4.6 | 91.9 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 4.5 | 31.8 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 4.3 | 17.4 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 4.3 | 86.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 4.3 | 829.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 4.3 | 12.8 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 4.2 | 113.3 | GO:0048156 | tau protein binding(GO:0048156) |
| 4.2 | 37.4 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 4.1 | 12.4 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 4.1 | 20.7 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 4.1 | 57.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 4.0 | 11.9 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 4.0 | 126.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 3.9 | 74.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 3.9 | 62.3 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 3.9 | 50.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 3.9 | 15.5 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 3.9 | 7.7 | GO:0004470 | malic enzyme activity(GO:0004470) |
| 3.9 | 38.5 | GO:0030515 | snoRNA binding(GO:0030515) |
| 3.8 | 18.9 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 3.8 | 26.3 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 3.7 | 18.6 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 3.7 | 14.9 | GO:0034452 | dynactin binding(GO:0034452) |
| 3.7 | 81.2 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 3.6 | 21.9 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 3.6 | 7.3 | GO:0070336 | flap-structured DNA binding(GO:0070336) |
| 3.6 | 10.7 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 3.5 | 71.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 3.5 | 3.5 | GO:0032407 | MutSalpha complex binding(GO:0032407) |
| 3.5 | 7.1 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 3.5 | 17.6 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 3.5 | 371.4 | GO:0008565 | protein transporter activity(GO:0008565) |
| 3.5 | 49.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 3.5 | 48.8 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 3.5 | 38.3 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 3.5 | 17.3 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 3.5 | 34.6 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 3.4 | 17.2 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 3.4 | 103.1 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 3.4 | 34.3 | GO:0016892 | endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
| 3.4 | 10.2 | GO:0016662 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 3.4 | 23.6 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 3.4 | 27.0 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 3.4 | 40.2 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 3.3 | 9.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 3.3 | 23.1 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 3.3 | 32.7 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 3.2 | 3.2 | GO:0070259 | tyrosyl-DNA phosphodiesterase activity(GO:0070259) |
| 3.1 | 12.6 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 3.1 | 12.5 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 3.1 | 21.6 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 3.1 | 49.1 | GO:0070061 | fructose binding(GO:0070061) |
| 3.0 | 102.1 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 3.0 | 219.9 | GO:0005507 | copper ion binding(GO:0005507) |
| 3.0 | 44.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 2.9 | 5.9 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
| 2.9 | 8.8 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 2.9 | 14.7 | GO:0004619 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 2.9 | 23.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 2.9 | 5.7 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 2.9 | 17.2 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 2.9 | 17.2 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 2.8 | 16.9 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 2.8 | 5.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 2.8 | 318.3 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 2.8 | 14.0 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 2.8 | 5.5 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 2.7 | 24.6 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 2.7 | 40.9 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 2.6 | 26.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 2.6 | 15.6 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 2.6 | 31.0 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 2.6 | 20.4 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 2.5 | 17.8 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 2.5 | 17.8 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 2.5 | 73.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 2.5 | 10.0 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 2.5 | 9.8 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 2.4 | 36.6 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 2.4 | 41.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 2.4 | 36.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 2.4 | 7.3 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 2.4 | 7.2 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 2.4 | 2.4 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 2.4 | 30.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 2.3 | 9.4 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 2.3 | 9.2 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 2.3 | 68.3 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 2.2 | 22.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 2.2 | 13.3 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 2.2 | 17.7 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 2.2 | 77.4 | GO:0019956 | chemokine binding(GO:0019956) |
| 2.1 | 21.5 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 2.1 | 66.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 2.1 | 51.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 2.1 | 12.7 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 2.1 | 6.3 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 2.1 | 31.6 | GO:0019843 | rRNA binding(GO:0019843) |
| 2.1 | 16.8 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 2.1 | 8.4 | GO:0043515 | kinetochore binding(GO:0043515) |
| 2.1 | 30.9 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 2.0 | 40.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 2.0 | 8.0 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 1.9 | 7.8 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) |
| 1.9 | 33.0 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 1.9 | 65.7 | GO:0005123 | death receptor binding(GO:0005123) |
| 1.9 | 50.2 | GO:0046961 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 1.9 | 167.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 1.9 | 9.6 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 1.9 | 9.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.9 | 9.5 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 1.9 | 16.9 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 1.8 | 31.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 1.8 | 10.9 | GO:0000182 | rDNA binding(GO:0000182) |
| 1.8 | 9.1 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 1.8 | 71.2 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 1.8 | 5.3 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 1.8 | 17.6 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 1.7 | 12.0 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 1.7 | 190.4 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 1.6 | 3.3 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 1.6 | 11.5 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 1.6 | 3.3 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 1.6 | 4.8 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 1.6 | 25.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 1.6 | 95.6 | GO:0019213 | deacetylase activity(GO:0019213) |
| 1.6 | 43.0 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 1.6 | 22.0 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 1.5 | 50.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 1.5 | 36.9 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 1.5 | 1.5 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
| 1.5 | 12.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 1.5 | 65.0 | GO:0030145 | manganese ion binding(GO:0030145) |
| 1.5 | 16.5 | GO:0055106 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 1.5 | 4.5 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 1.5 | 17.8 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 1.5 | 20.6 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 1.5 | 4.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 1.4 | 7.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 1.4 | 11.2 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 1.4 | 11.0 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.4 | 11.0 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.3 | 145.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 1.3 | 33.0 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 1.3 | 40.6 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 1.3 | 11.5 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 1.3 | 36.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 1.2 | 21.1 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 1.1 | 22.9 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 1.1 | 7.9 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 1.1 | 4.5 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 1.1 | 34.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 1.1 | 6.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 1.1 | 16.4 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 1.1 | 5.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 1.1 | 27.6 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 1.1 | 12.7 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 1.1 | 2.1 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 1.0 | 17.8 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 1.0 | 19.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 1.0 | 9.3 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 1.0 | 10.1 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 1.0 | 347.8 | GO:0045296 | cadherin binding(GO:0045296) |
| 1.0 | 38.0 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 1.0 | 28.9 | GO:0003785 | actin monomer binding(GO:0003785) |
| 1.0 | 6.9 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 1.0 | 6.8 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 1.0 | 5.7 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 1.0 | 21.9 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.9 | 19.4 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.9 | 15.7 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.9 | 11.9 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 0.9 | 25.4 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.9 | 40.8 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.9 | 3.6 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.9 | 4.5 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.9 | 5.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.9 | 32.4 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.9 | 3.5 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.9 | 3.4 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.9 | 7.7 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.8 | 4.2 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.8 | 54.8 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.8 | 4.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.8 | 3.2 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.8 | 22.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.8 | 6.3 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.8 | 8.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.7 | 3.7 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.7 | 14.4 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.7 | 8.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.7 | 5.7 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.7 | 8.5 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.7 | 5.6 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.7 | 11.9 | GO:0005537 | mannose binding(GO:0005537) |
| 0.7 | 8.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.7 | 6.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.7 | 27.6 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.7 | 15.4 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.7 | 12.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.7 | 5.3 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 0.7 | 12.7 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.6 | 9.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.6 | 31.0 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 0.6 | 2.5 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.6 | 3.2 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.6 | 6.2 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.6 | 13.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.6 | 2.4 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.6 | 78.7 | GO:0005178 | integrin binding(GO:0005178) |
| 0.6 | 40.5 | GO:0019003 | GDP binding(GO:0019003) |
| 0.5 | 4.4 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.5 | 3.2 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.5 | 4.2 | GO:0018812 | 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) |
| 0.5 | 3.7 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.5 | 16.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.5 | 2.0 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.5 | 4.0 | GO:0015924 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.5 | 10.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.5 | 0.9 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.5 | 10.8 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.5 | 2.3 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.4 | 29.5 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.4 | 2.2 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.4 | 11.5 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.4 | 1.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.4 | 8.9 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.4 | 0.4 | GO:0016453 | C-acetyltransferase activity(GO:0016453) |
| 0.4 | 2.5 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.4 | 4.1 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.4 | 69.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.4 | 38.0 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.4 | 4.2 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.4 | 2.5 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.4 | 1.4 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.4 | 1.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.4 | 22.5 | GO:0008144 | drug binding(GO:0008144) |
| 0.3 | 1.0 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.3 | 1.0 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.3 | 1.7 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.3 | 2.7 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.3 | 1.4 | GO:0009881 | photoreceptor activity(GO:0009881) |
| 0.3 | 1.3 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.3 | 6.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.3 | 2.6 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.3 | 2.2 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.3 | 4.4 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.3 | 7.9 | GO:0042171 | lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.3 | 8.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.3 | 17.5 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
| 0.3 | 64.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.3 | 45.1 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.3 | 1.8 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.3 | 1.5 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.3 | 2.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 5.2 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 1.2 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.2 | 2.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.2 | 5.5 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.2 | 2.5 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.2 | 14.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.2 | 2.0 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.2 | 3.3 | GO:0001637 | G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) |
| 0.2 | 2.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 1.3 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 1.7 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 0.6 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 1.5 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.2 | 0.5 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.2 | 1.6 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.2 | 1.8 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.2 | 6.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 1.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.1 | 2.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.1 | 1.4 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.1 | 2.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 1.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.1 | 0.2 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.1 | 1.1 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.1 | 0.5 | GO:0097493 | extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493) |
| 0.1 | 3.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.2 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.1 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
| 0.1 | 0.4 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 0.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 3.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.4 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.1 | 0.9 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 0.2 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.1 | 1.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 64.3 | GO:0003723 | RNA binding(GO:0003723) |
| 0.1 | 5.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.3 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.3 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 0.2 | GO:0031896 | alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896) |
| 0.0 | 0.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 1.3 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.0 | 0.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.1 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.1 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 22.7 | 453.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 15.6 | 296.9 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 13.7 | 1951.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 7.0 | 351.1 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 5.1 | 450.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 4.4 | 65.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 4.2 | 16.9 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 3.9 | 47.0 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 3.8 | 30.3 | PID IFNG PATHWAY | IFN-gamma pathway |
| 3.7 | 180.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 3.7 | 47.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 3.2 | 301.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 3.0 | 71.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 2.7 | 8.1 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 2.5 | 82.6 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 2.4 | 24.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 2.4 | 114.3 | PID ATR PATHWAY | ATR signaling pathway |
| 2.4 | 204.5 | PID E2F PATHWAY | E2F transcription factor network |
| 2.4 | 164.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 2.4 | 413.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 2.1 | 31.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 2.0 | 10.2 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 2.0 | 96.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.9 | 97.3 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 1.9 | 5.8 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 1.8 | 158.6 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 1.8 | 64.5 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 1.7 | 33.7 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 1.7 | 10.1 | PID BARD1 PATHWAY | BARD1 signaling events |
| 1.6 | 21.1 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 1.6 | 131.3 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 1.6 | 131.0 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 1.5 | 6.1 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 1.5 | 26.4 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 1.5 | 40.7 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 1.4 | 75.3 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 1.3 | 44.4 | PID INSULIN PATHWAY | Insulin Pathway |
| 1.3 | 38.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 1.2 | 20.6 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 1.1 | 57.2 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 1.1 | 13.1 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 1.1 | 47.8 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 1.0 | 45.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 1.0 | 57.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 1.0 | 17.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 1.0 | 28.7 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.9 | 40.2 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.9 | 51.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.9 | 11.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.7 | 20.5 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.7 | 10.2 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.7 | 15.9 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.6 | 12.5 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.6 | 32.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.6 | 51.5 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.6 | 9.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.5 | 7.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.5 | 12.3 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.5 | 21.9 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.5 | 30.6 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.5 | 4.7 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.5 | 15.6 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.5 | 3.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.4 | 13.7 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.4 | 5.4 | PID ATM PATHWAY | ATM pathway |
| 0.4 | 16.9 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.3 | 4.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.3 | 1.8 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.3 | 5.5 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.3 | 8.8 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.2 | 5.0 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.2 | 7.1 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 2.8 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.2 | 3.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 1.4 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.1 | 1.8 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 0.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 2.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 1.9 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.5 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.7 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.6 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 37.7 | 565.1 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 37.4 | 37.4 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 25.9 | 518.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 22.0 | 198.2 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 16.8 | 553.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 16.2 | 324.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 14.5 | 855.8 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 10.8 | 389.7 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 10.4 | 270.2 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 9.0 | 81.4 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 9.0 | 215.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 8.4 | 477.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 8.3 | 200.1 | REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | Genes involved in Assembly of the pre-replicative complex |
| 7.9 | 87.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 7.9 | 228.9 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 7.4 | 294.2 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 7.3 | 278.1 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 7.2 | 200.6 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 7.1 | 645.3 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 6.9 | 83.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 6.4 | 185.6 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 6.0 | 71.6 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 5.7 | 434.1 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 5.6 | 100.0 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 5.5 | 49.8 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 5.5 | 274.6 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 5.1 | 40.6 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 5.0 | 136.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 4.9 | 73.5 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 4.8 | 91.4 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 4.8 | 158.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 4.8 | 190.5 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 4.7 | 71.1 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 4.7 | 52.1 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 4.4 | 142.2 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 4.3 | 511.3 | REACTOME INFLUENZA LIFE CYCLE | Genes involved in Influenza Life Cycle |
| 4.0 | 125.3 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 4.0 | 83.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 3.9 | 89.1 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 3.9 | 505.6 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 3.8 | 53.7 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 3.7 | 36.7 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 3.7 | 226.5 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 3.5 | 14.2 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 3.4 | 57.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 3.2 | 72.9 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 3.1 | 21.8 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 3.0 | 129.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 3.0 | 156.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 3.0 | 41.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 2.9 | 17.2 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 2.9 | 63.0 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 2.8 | 89.3 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 2.7 | 37.6 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 2.6 | 164.0 | REACTOME TRANSLATION | Genes involved in Translation |
| 2.5 | 61.0 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 2.5 | 55.5 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 2.5 | 66.7 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 2.4 | 33.4 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 2.3 | 51.3 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 2.3 | 124.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 2.3 | 63.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 2.2 | 20.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 2.2 | 52.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 2.1 | 2.1 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 2.1 | 71.9 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 2.0 | 16.3 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 2.0 | 47.2 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 1.9 | 207.0 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 1.8 | 18.3 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 1.8 | 31.0 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 1.8 | 72.2 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 1.8 | 14.0 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 1.7 | 25.7 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.7 | 45.3 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 1.7 | 23.2 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 1.6 | 42.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 1.6 | 65.7 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 1.6 | 47.5 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 1.6 | 44.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 1.5 | 114.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 1.5 | 32.7 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.5 | 10.2 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 1.4 | 12.5 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 1.4 | 49.7 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 1.3 | 37.8 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 1.3 | 76.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 1.3 | 189.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.3 | 35.8 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 1.2 | 18.4 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 1.2 | 30.2 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 1.0 | 22.4 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.9 | 9.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.9 | 26.2 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.9 | 10.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.9 | 18.7 | REACTOME METABOLISM OF PROTEINS | Genes involved in Metabolism of proteins |
| 0.9 | 26.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.8 | 7.2 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.8 | 34.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.7 | 11.8 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.7 | 24.5 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.7 | 7.9 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.7 | 5.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.6 | 70.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.6 | 13.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.5 | 60.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.5 | 30.5 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.5 | 4.5 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.5 | 5.9 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.5 | 3.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.5 | 5.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.4 | 9.9 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.4 | 4.9 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.4 | 28.9 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.4 | 13.5 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.4 | 10.2 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.4 | 10.7 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.3 | 3.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.3 | 24.4 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.3 | 1.8 | REACTOME SIGNALLING TO RAS | Genes involved in Signalling to RAS |
| 0.3 | 2.1 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.3 | 2.4 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.3 | 1.6 | REACTOME SIGNALING BY WNT | Genes involved in Signaling by Wnt |
| 0.3 | 2.8 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.2 | 4.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.2 | 5.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 4.5 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.2 | 23.1 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.2 | 3.5 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.2 | 2.1 | REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT | Genes involved in Lipid digestion, mobilization, and transport |
| 0.2 | 9.1 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 2.9 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.1 | 0.9 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 2.1 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.1 | 0.9 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.1 | 4.8 | REACTOME PI METABOLISM | Genes involved in PI Metabolism |
| 0.1 | 1.6 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |