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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MYBL1

Z-value: 1.74

Motif logo

Transcription factors associated with MYBL1

Gene Symbol Gene ID Gene Info
ENSG00000185697.17 MYBL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBL1hg38_v1_chr8_-_66613208_666132240.187.7e-03Click!

Activity profile of MYBL1 motif

Sorted Z-values of MYBL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MYBL1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_55407719 10.38 ENST00000587845.5
ENST00000589978.1
ENST00000264552.14
ubiquitin conjugating enzyme E2 S
chr13_+_36431510 10.00 ENST00000630422.2
cyclin A1
chr11_+_18412292 9.64 ENST00000541669.6
ENST00000280704.8
lactate dehydrogenase C
chr18_+_657637 8.40 ENST00000323274.15
thymidylate synthetase
chr11_+_7088991 7.73 ENST00000306904.7
RBMX like 2
chr15_+_66504959 7.43 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr17_+_68035636 7.33 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
karyopherin subunit alpha 2
chr15_+_66505289 7.31 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr3_-_149086488 7.28 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
helicase like transcription factor
chr17_+_68035722 7.15 ENST00000679078.1
ENST00000330459.8
ENST00000584026.6
karyopherin subunit alpha 2
chr6_+_24774925 7.08 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chrX_-_141585011 6.93 ENST00000370519.3
sperm protein associated with the nucleus, X-linked, family member A1
chr19_-_14419331 5.96 ENST00000242776.9
DExD-box helicase 39A
chr16_+_67326808 5.78 ENST00000329956.11
ENST00000569499.6
ENST00000561948.1
leucine rich repeat containing 36
chr1_-_211675557 5.66 ENST00000366998.4
ENST00000366999.9
ENST00000540251.5
NIMA related kinase 2
chr1_-_202808406 5.49 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
lysine demethylase 5B
chr15_+_89243945 5.32 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chr13_+_30427950 5.31 ENST00000436446.1
ubiquitin conjugating enzyme E2 L5
chr14_+_64540734 5.30 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr3_+_193241190 5.24 ENST00000264735.4
phospholipase A and acyltransferase 1
chr1_+_98661666 5.20 ENST00000529992.5
sorting nexin 7
chr17_-_81911128 5.00 ENST00000573927.5
ENST00000331285.7
ENST00000572157.1
phosphate cytidylyltransferase 2, ethanolamine
chr1_+_98661709 4.85 ENST00000306121.8
sorting nexin 7
chr3_+_193241128 4.81 ENST00000650797.1
phospholipase A and acyltransferase 1
chr12_-_122225992 4.57 ENST00000446652.5
ENST00000267169.11
ENST00000464942.7
ENST00000353548.11
diablo IAP-binding mitochondrial protein
chr11_+_125903320 4.55 ENST00000525943.1
DEAD-box helicase 25
chr22_-_22559229 4.54 ENST00000405655.8
ENST00000406503.1
ENST00000439106.5
ENST00000402697.5
ENST00000543184.5
ENST00000398743.6
PRAME nuclear receptor transcriptional regulator
chr2_+_189784435 4.46 ENST00000409985.5
ENST00000441310.7
ENST00000446877.5
ENST00000409823.7
ENST00000374826.8
ENST00000424766.5
ENST00000447232.6
PMS1 homolog 1, mismatch repair system component
chr7_-_18027839 4.44 ENST00000506618.5
phosphoribosyl pyrophosphate synthetase 1 like 1
chr5_-_69369988 4.44 ENST00000380818.7
ENST00000328663.8
adenylate kinase 6
TATA-box binding protein associated factor 9
chr7_+_73692596 4.30 ENST00000453316.1
BUD23 rRNA methyltransferase and ribosome maturation factor
chr1_-_202808464 4.25 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
lysine demethylase 5B
chr5_+_131264043 4.21 ENST00000505065.2
ENST00000503291.5
ENST00000360515.7
CDC42 small effector 2
chr17_-_58692032 3.97 ENST00000349033.10
ENST00000389934.7
testis expressed 14, intercellular bridge forming factor
chrX_-_141242512 3.95 ENST00000358993.3
SPANX family member C
chr6_-_52763473 3.90 ENST00000493422.3
glutathione S-transferase alpha 2
chr17_-_58692021 3.88 ENST00000240361.12
testis expressed 14, intercellular bridge forming factor
chr8_-_99893697 3.85 ENST00000518171.5
ENST00000520468.7
cytochrome c oxidase subunit 6C
chrX_+_141589700 3.83 ENST00000370518.4
SPANX family member A2
chr14_+_77708068 3.81 ENST00000613856.4
SRA stem-loop interacting RNA binding protein
chr3_+_160399630 3.78 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chrY_+_2841864 3.73 ENST00000430575.1
ribosomal protein S4 Y-linked 1
chr1_+_23019415 3.62 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
lysine demethylase 1A
chr6_-_75250284 3.61 ENST00000370081.6
cytochrome c oxidase subunit 7A2
chr12_+_130337872 3.55 ENST00000245255.7
piwi like RNA-mediated gene silencing 1
chr20_-_44960348 3.53 ENST00000372813.4
translocase of outer mitochondrial membrane 34
chrX_-_105220693 3.50 ENST00000609007.3
ENST00000600991.6
testis expressed 13A
chr1_-_193105373 3.48 ENST00000367439.8
glutaredoxin 2
chr17_-_81911200 3.47 ENST00000570391.5
phosphate cytidylyltransferase 2, ethanolamine
chr15_+_41286011 3.47 ENST00000661438.1
novel protein
chr4_-_173334385 3.39 ENST00000446922.6
high mobility group box 2
chr10_+_35127023 3.35 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
cAMP responsive element modulator
chr17_-_9575811 3.31 ENST00000306357.9
ENST00000574431.5
syntaxin 8
chr12_+_69359673 3.30 ENST00000548020.5
ENST00000549685.5
ENST00000247843.7
ENST00000552955.1
YEATS domain containing 4
chrX_-_115017569 3.30 ENST00000243213.2
interleukin 13 receptor subunit alpha 2
chr5_+_10250216 3.25 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr14_-_58427158 3.23 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr10_+_35126791 3.22 ENST00000474362.5
ENST00000374721.7
cAMP responsive element modulator
chr2_+_96335752 3.17 ENST00000240423.9
ENST00000427946.5
ENST00000435975.5
ENST00000456906.5
ENST00000455200.5
non-SMC condensin I complex subunit H
chr18_+_22933819 3.11 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RB binding protein 8, endonuclease
chrY_+_2841594 3.07 ENST00000250784.13
ribosomal protein S4 Y-linked 1
chr1_+_10430384 3.05 ENST00000470413.6
ENST00000602787.6
ENST00000309048.8
CENPS-CORT readthrough
centromere protein S
chr7_-_76626127 2.99 ENST00000454397.1
POM121 and ZP3 fusion
chr6_+_13615322 2.99 ENST00000451315.7
nucleolar protein 7
chr11_-_119057105 2.98 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
hypoxia up-regulated 1
chr11_-_119057218 2.96 ENST00000652093.1
hypoxia up-regulated 1
chr8_-_25458389 2.96 ENST00000221200.9
potassium channel tetramerization domain containing 9
chr15_-_29968864 2.95 ENST00000356107.11
tight junction protein 1
chr1_+_96721762 2.92 ENST00000675735.1
ENST00000609116.5
ENST00000674951.1
ENST00000426398.3
ENST00000370197.5
ENST00000370198.5
polypyrimidine tract binding protein 2
chr11_-_119057185 2.88 ENST00000614668.4
ENST00000617285.5
hypoxia up-regulated 1
chr14_-_58427114 2.85 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr17_-_1400168 2.84 ENST00000573026.1
ENST00000575977.1
ENST00000571732.5
ENST00000264335.13
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
chr10_+_26697653 2.76 ENST00000376215.10
decaprenyl diphosphate synthase subunit 1
chr17_-_42964437 2.71 ENST00000427569.7
ENST00000430739.5
alanyl-tRNA synthetase domain containing 1
chr14_-_58427134 2.63 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr5_+_10250272 2.58 ENST00000280326.9
ENST00000625723.1
chaperonin containing TCP1 subunit 5
chr7_+_26201705 2.56 ENST00000396386.7
ENST00000456948.5
ENST00000409747.5
chromobox 3
chr4_+_2963580 2.50 ENST00000398051.8
ENST00000503518.2
G protein-coupled receptor kinase 4
chr13_-_23375431 2.50 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr7_-_150323489 2.46 ENST00000683684.1
ENST00000478393.5
actin related protein 3C
chr4_+_2963535 2.41 ENST00000398052.9
G protein-coupled receptor kinase 4
chr13_-_37059603 2.40 ENST00000497318.1
ENST00000475892.5
ENST00000356185.7
ENST00000350612.11
ENST00000360252.8
SPT20 homolog, SAGA complex component
chr14_-_58427489 2.38 ENST00000555593.5
translocase of inner mitochondrial membrane 9
chr6_-_56843153 2.37 ENST00000361203.7
ENST00000523817.1
dystonin
chr8_-_81686274 2.35 ENST00000449740.6
ENST00000311489.8
ENST00000521360.5
ENST00000519964.5
ENST00000256108.10
ENST00000518202.5
inositol monophosphatase 1
chr17_+_49788672 2.34 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr14_-_58427509 2.31 ENST00000395159.7
translocase of inner mitochondrial membrane 9
chr22_+_22644475 2.27 ENST00000618722.4
ENST00000652219.1
ENST00000480559.6
ENST00000448514.2
ENST00000652249.1
ENST00000651213.1
gamma-glutamyltransferase light chain 2
chr15_-_34437769 2.19 ENST00000359187.5
golgin A8 family member A
chr3_+_139344530 2.19 ENST00000478464.5
mitochondrial ribosomal protein S22
chr5_-_147453888 2.18 ENST00000398514.7
dihydropyrimidinase like 3
chr16_-_56451316 2.17 ENST00000300291.10
nudix hydrolase 21
chr20_+_1118590 2.14 ENST00000246015.8
ENST00000335877.11
proteasome inhibitor subunit 1
chr15_+_78873723 2.14 ENST00000559690.5
ENST00000559158.5
mortality factor 4 like 1
chr2_+_27663880 2.13 ENST00000618046.4
ENST00000613517.4
solute carrier family 4 member 1 adaptor protein
chrX_+_115561162 2.13 ENST00000355899.8
ENST00000626746.2
ENST00000289290.7
plastin 3
chr1_-_25859352 2.13 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr16_-_15381047 2.12 ENST00000534094.1
nuclear pore complex interacting protein family member A5
chr1_-_51878799 2.11 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chr13_-_37059432 2.04 ENST00000464744.5
SPT20 homolog, SAGA complex component
chr21_-_32612577 2.03 ENST00000673985.1
ENST00000382549.8
CFAP298-TCP10L readthrough
cilia and flagella associated protein 298
chr19_+_57584131 2.02 ENST00000536878.6
ENST00000597219.1
ENST00000598689.1
ENST00000597850.2
zinc finger protein interacting with K protein 1
chr16_+_4734457 2.00 ENST00000590191.1
chromosome 16 open reading frame 71
chr2_-_207624983 2.00 ENST00000448007.6
ENST00000432416.5
ENST00000411432.5
ENST00000458426.5
ENST00000406927.6
ENST00000425132.5
methyltransferase like 21A
chr4_+_174918400 1.96 ENST00000404450.8
ENST00000514159.1
ADAM metallopeptidase domain 29
chr17_-_32342132 1.88 ENST00000577809.6
ENST00000225805.8
chromosome 17 open reading frame 75
chr14_+_89955895 1.87 ENST00000393452.7
ENST00000554180.5
ENST00000335725.9
ENST00000393454.6
ENST00000553617.5
ENST00000556867.1
ENST00000553527.1
tyrosyl-DNA phosphodiesterase 1
chr2_-_43995950 1.87 ENST00000683590.1
ENST00000683623.1
ENST00000682779.1
ENST00000682546.1
ENST00000683220.1
ENST00000683125.1
ENST00000683833.1
ENST00000683989.1
ENST00000682480.1
ENST00000260665.12
ENST00000682308.1
ENST00000682885.1
ENST00000409659.6
ENST00000447246.2
leucine rich pentatricopeptide repeat containing
chr5_-_147831627 1.85 ENST00000510027.2
serine peptidase inhibitor Kazal type 1
chr1_+_172533104 1.84 ENST00000616058.4
ENST00000263688.4
ENST00000610051.5
SUN domain containing ossification factor
chr3_-_52705746 1.83 ENST00000487642.5
ENST00000464705.1
ENST00000491606.5
ENST00000266014.11
ENST00000478968.6
ENST00000497436.5
glycosyltransferase 8 domain containing 1
chr2_+_203328378 1.78 ENST00000430418.5
ENST00000261018.12
ENST00000295851.10
ENST00000424558.5
ENST00000417864.5
ENST00000422511.6
abl interactor 2
chr21_-_32612339 1.77 ENST00000440966.5
ENST00000290155.8
cilia and flagella associated protein 298
chr21_-_43659460 1.75 ENST00000443485.1
ENST00000291560.7
heat shock transcription factor 2 binding protein
chr12_-_56688156 1.69 ENST00000436399.6
prostaglandin E synthase 3
chr19_+_38335775 1.69 ENST00000410018.5
ENST00000409235.8
ENST00000409410.6
cation channel sperm associated auxiliary subunit gamma
chr12_-_120327762 1.65 ENST00000308366.9
ENST00000423423.3
phospholipase A2 group IB
chr14_+_67240713 1.63 ENST00000677382.1
membrane palmitoylated protein 5
chr8_-_140764386 1.60 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr2_+_112275588 1.60 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr19_+_39997031 1.59 ENST00000599504.5
ENST00000596894.5
ENST00000601138.5
ENST00000347077.9
ENST00000600094.5
zinc finger protein 546
chr4_+_174918355 1.59 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM metallopeptidase domain 29
chr17_+_75205659 1.55 ENST00000583569.5
ENST00000245544.9
ENST00000579324.5
ENST00000579298.5
nucleoporin 85
chr19_+_37218174 1.55 ENST00000590503.5
ENST00000684119.1
ENST00000589413.5
zinc finger protein 383
chr1_-_202159977 1.51 ENST00000367279.8
protein tyrosine phosphatase non-receptor type 7
chr1_+_19882374 1.51 ENST00000375120.4
OTU deubiquitinase 3
chr11_+_36594369 1.49 ENST00000678060.1
ENST00000446510.6
ENST00000676979.1
ENST00000677808.1
ENST00000617650.5
ENST00000334307.10
ENST00000531554.6
ENST00000679022.1
ENST00000347206.8
ENST00000534635.5
ENST00000676921.1
ENST00000678950.1
ENST00000530697.6
ENST00000527108.6
ENST00000532470.3
intraflagellar transport associated protein
chr16_-_5065911 1.49 ENST00000472572.8
ENST00000474471.7
chromosome 16 open reading frame 89
chrX_-_109733181 1.48 ENST00000673016.1
acyl-CoA synthetase long chain family member 4
chr8_-_116874746 1.47 ENST00000297338.7
RAD21 cohesin complex component
chr6_+_42879610 1.44 ENST00000493763.7
ENST00000304734.9
ribosomal protein L7 like 1
chr22_-_41946688 1.43 ENST00000404067.5
ENST00000402338.5
centromere protein M
chr19_-_53132873 1.43 ENST00000601493.5
ENST00000599261.5
ENST00000597503.5
ENST00000500065.8
ENST00000594011.5
ENST00000595193.5
ENST00000595813.5
ENST00000600574.5
ENST00000596051.1
ENST00000601110.5
ENST00000243643.9
ENST00000421033.5
zinc finger protein 415
chr16_-_5066024 1.43 ENST00000315997.5
chromosome 16 open reading frame 89
chr3_-_179451387 1.43 ENST00000675901.1
ENST00000232564.8
ENST00000674862.1
ENST00000497513.1
G protein subunit beta 4
chr1_-_84997079 1.43 ENST00000284027.5
ENST00000370608.8
mucolipin TRP cation channel 2
chr4_+_127730386 1.41 ENST00000281154.6
solute carrier family 25 member 31
chr19_+_53365687 1.40 ENST00000491101.5
ENST00000474037.6
ENST00000467003.1
ENST00000475179.5
ENST00000593918.1
zinc finger protein 525
chr5_-_850986 1.39 ENST00000283441.12
zinc finger DHHC-type containing 11
chr16_-_18368364 1.35 ENST00000528301.1
nuclear pore complex interacting protein family, member A9
chr13_+_45120493 1.35 ENST00000340473.8
general transcription factor IIF subunit 2
chr3_+_49940057 1.34 ENST00000422955.5
RNA binding motif protein 6
chr13_-_113864062 1.34 ENST00000327773.7
growth arrest specific 6
chr17_+_782340 1.33 ENST00000304478.9
mitochondrial rRNA methyltransferase 3
chr15_-_78299570 1.29 ENST00000560569.5
ENST00000558459.5
ENST00000558311.5
ENST00000267973.7
WD repeat domain 61
chr10_-_33334382 1.29 ENST00000374823.9
ENST00000374821.9
ENST00000374816.7
neuropilin 1
chr3_+_49940007 1.29 ENST00000442092.5
ENST00000443081.5
RNA binding motif protein 6
chr7_+_16646131 1.29 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
basic leucine zipper and W2 domains 2
chr19_-_39032525 1.29 ENST00000509137.6
ENST00000292853.9
F-box protein 27
chr5_-_147831663 1.26 ENST00000296695.10
serine peptidase inhibitor Kazal type 1
chr15_-_55196899 1.24 ENST00000677147.1
ENST00000260443.9
ENST00000677730.1
ribosomal L24 domain containing 1
chr2_-_132670194 1.24 ENST00000397463.3
LY6/PLAUR domain containing 1
chrM_+_4467 1.22 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr8_-_99893622 1.21 ENST00000520271.5
ENST00000522940.5
ENST00000523016.1
ENST00000517682.6
ENST00000297564.6
cytochrome c oxidase subunit 6C
chr11_-_129895532 1.21 ENST00000526884.1
ENST00000682444.1
ENST00000529319.5
ENST00000532225.5
nuclear factor related to kappaB binding protein
chr1_-_159900112 1.20 ENST00000479940.2
ENST00000368099.9
cilia and flagella associated protein 45
chr7_-_124929938 1.19 ENST00000668382.1
ENST00000655761.1
ENST00000393329.5
protection of telomeres 1
chr7_-_124929801 1.18 ENST00000653241.1
ENST00000664366.1
ENST00000446993.6
ENST00000654766.1
ENST00000357628.8
ENST00000609702.5
protection of telomeres 1
chr1_-_227318125 1.18 ENST00000366764.7
CDC42 binding protein kinase alpha
chr19_+_50025714 1.18 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
zinc finger protein 473
chr3_+_119597874 1.17 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A
chr16_+_56451513 1.16 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr21_-_38661694 1.16 ENST00000417133.6
ENST00000398910.5
ENST00000442448.5
ENST00000429727.6
ETS transcription factor ERG
chr17_-_43942472 1.16 ENST00000225992.8
pancreatic polypeptide
chr19_-_6424802 1.16 ENST00000600480.2
KH-type splicing regulatory protein
chr17_+_42020066 1.13 ENST00000587337.1
ENST00000479407.5
NFKB inhibitor interacting Ras like 2
chr6_+_36594354 1.13 ENST00000373715.11
serine and arginine rich splicing factor 3
chr6_+_112054075 1.12 ENST00000230529.9
ENST00000604763.5
ENST00000368666.7
ENST00000674325.1
ENST00000483439.1
ENST00000409166.5
cellular communication network factor 6
chr14_-_77708003 1.12 ENST00000216489.8
alkB homolog 1, histone H2A dioxygenase
chr3_+_49940134 1.11 ENST00000266022.9
RNA binding motif protein 6
chr22_+_32474794 1.09 ENST00000266087.12
F-box protein 7
chr14_+_20891385 1.08 ENST00000304639.4
ribonuclease A family member 3
chr1_-_68050615 1.07 ENST00000646789.1
DIRAS family GTPase 3
chr6_+_70667863 1.06 ENST00000370455.8
small ArfGAP 1
chr12_-_91146195 1.06 ENST00000548218.1
decorin
chr14_+_58427686 1.05 ENST00000650904.1
ENST00000652326.2
ENST00000554463.5
ENST00000555833.5
KIAA0586
chr1_-_151909501 1.04 ENST00000368814.8
thioesterase superfamily member 4
chr10_-_35090545 1.03 ENST00000374751.7
ENST00000626172.2
cullin 2
chr12_+_110614097 1.03 ENST00000471804.7
ENST00000377654.5
ENST00000614115.5
ENST00000397655.7
ENST00000549123.6
ENST00000679401.1
ENST00000397659.9
ENST00000680445.1
tectonic family member 1
chr17_-_41918966 1.03 ENST00000537919.5
ENST00000353196.5
ENST00000393896.6
ATP citrate lyase
chr16_+_474850 1.02 ENST00000450428.5
ENST00000452814.5
RAB11 family interacting protein 3
chr1_-_244864526 1.01 ENST00000640218.2
heterogeneous nuclear ribonucleoprotein U
chr5_+_108747879 1.00 ENST00000281092.9
FER tyrosine kinase
chr19_+_24087147 1.00 ENST00000611359.3
ENST00000616028.2
zinc finger protein 254
chr22_-_41947087 0.99 ENST00000407253.7
ENST00000215980.10
centromere protein M
chr9_-_92293674 0.99 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
isoleucyl-tRNA synthetase 1
chr1_-_83999097 0.98 ENST00000260505.13
ENST00000610996.1
tubulin tyrosine ligase like 7
chr3_+_52706092 0.98 ENST00000619898.5
signal peptidase complex subunit 1
chr6_-_32224060 0.98 ENST00000375023.3
notch receptor 4
chr19_+_35748549 0.98 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr17_-_41918944 0.98 ENST00000352035.7
ENST00000590770.5
ENST00000590151.5
ATP citrate lyase
chr8_+_132775340 0.98 ENST00000622263.4
ENST00000220847.8
ENST00000395379.5
ENST00000395386.7
ENST00000485595.5
ENST00000337920.8
PHD finger protein 20 like 1
chr3_+_52705828 0.97 ENST00000233025.11
signal peptidase complex subunit 1
chr7_-_80922354 0.95 ENST00000419255.6
semaphorin 3C
chr4_+_146175702 0.95 ENST00000296581.11
ENST00000649747.1
ENST00000502781.5
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr8_+_103298433 0.94 ENST00000522566.5
frizzled class receptor 6
chr6_-_89638716 0.94 ENST00000626778.2
ENST00000520441.5
ENST00000523377.2
ENST00000520318.1
LYR motif containing 2
chr6_-_33314202 0.94 ENST00000426633.6
ENST00000467025.1
TAP binding protein
chrX_-_109733220 0.94 ENST00000672282.1
ENST00000340800.7
acyl-CoA synthetase long chain family member 4
chr6_+_35259703 0.93 ENST00000373953.8
ENST00000339411.5
zinc finger protein 76

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
2.6 10.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.4 9.6 GO:0019249 lactate biosynthetic process(GO:0019249)
2.1 8.4 GO:0019860 uracil metabolic process(GO:0019860)
1.9 9.3 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
1.5 13.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.4 4.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
1.4 5.7 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
1.4 7.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
1.2 7.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.1 7.8 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.9 2.8 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.9 3.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.9 4.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.8 2.4 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.6 1.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.6 2.9 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.6 2.3 GO:0072708 response to sorbitol(GO:0072708)
0.6 4.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.6 0.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.5 3.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.5 3.5 GO:0034587 piRNA metabolic process(GO:0034587) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.5 1.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.5 3.0 GO:0035803 egg coat formation(GO:0035803)
0.5 4.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.4 1.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.4 8.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 3.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.4 14.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 5.8 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 1.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 1.6 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.4 7.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.4 2.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.4 1.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.4 4.3 GO:0033007 negative regulation of mast cell activation involved in immune response(GO:0033007)
0.4 4.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.3 9.7 GO:0007141 male meiosis I(GO:0007141)
0.3 1.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.3 1.3 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.3 4.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 1.3 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 3.5 GO:0042262 DNA protection(GO:0042262)
0.3 0.9 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 3.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.3 2.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 0.8 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.3 3.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 1.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 1.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.2 4.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 0.9 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 2.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.9 GO:0000012 single strand break repair(GO:0000012)
0.2 12.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 5.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 2.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 0.8 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.2 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 2.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 4.3 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 1.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 4.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.7 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.9 GO:0030656 regulation of vitamin metabolic process(GO:0030656)
0.1 3.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 1.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 6.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.6 GO:0051964 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.1 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 2.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 6.1 GO:0006301 postreplication repair(GO:0006301)
0.1 12.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 2.0 GO:0006465 signal peptide processing(GO:0006465)
0.1 1.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 3.2 GO:0006298 mismatch repair(GO:0006298)
0.1 2.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 2.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 1.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.7 GO:0035036 sperm-egg recognition(GO:0035036)
0.1 3.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.5 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 6.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.2 GO:0032098 regulation of appetite(GO:0032098)
0.0 1.2 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.1 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0071287 cellular response to manganese ion(GO:0071287)
0.0 1.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 14.1 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 1.8 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 2.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.7 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 1.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 2.0 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 1.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 4.5 GO:0007369 gastrulation(GO:0007369)
0.0 0.3 GO:0006702 androgen biosynthetic process(GO:0006702) estrogen biosynthetic process(GO:0006703)
0.0 2.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.0 1.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.7 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 4.2 GO:0016050 vesicle organization(GO:0016050)
0.0 0.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.7 GO:1990423 RZZ complex(GO:1990423)
2.5 10.0 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
2.2 13.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
1.4 7.0 GO:0036128 CatSper complex(GO:0036128)
1.1 3.2 GO:0000799 nuclear condensin complex(GO:0000799)
1.0 3.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.9 8.1 GO:0033391 chromatoid body(GO:0033391)
0.8 3.8 GO:0000796 condensin complex(GO:0000796)
0.6 8.9 GO:0000124 SAGA complex(GO:0000124)
0.6 8.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 2.4 GO:0031673 H zone(GO:0031673)
0.4 5.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.4 1.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 4.5 GO:0032389 MutLalpha complex(GO:0032389)
0.4 1.3 GO:0055087 Ski complex(GO:0055087)
0.4 1.5 GO:0000798 nuclear cohesin complex(GO:0000798)
0.4 1.1 GO:1990038 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
0.3 9.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 2.4 GO:0070187 telosome(GO:0070187)
0.2 2.5 GO:0070852 cell body fiber(GO:0070852)
0.2 2.2 GO:0042382 paraspeckles(GO:0042382)
0.2 4.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 2.0 GO:0005787 signal peptidase complex(GO:0005787)
0.2 1.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.2 4.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 1.4 GO:0061700 GATOR2 complex(GO:0061700)
0.2 5.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 1.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 0.9 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 15.3 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 1.8 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 8.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.3 GO:0097443 sorting endosome(GO:0097443)
0.1 1.0 GO:0030891 VCB complex(GO:0030891)
0.1 1.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 6.8 GO:0005844 polysome(GO:0005844)
0.1 1.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 2.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 14.9 GO:0031514 motile cilium(GO:0031514)
0.1 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 2.9 GO:0005921 gap junction(GO:0005921)
0.1 1.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.2 GO:0032437 cuticular plate(GO:0032437)
0.1 2.1 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.5 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.2 GO:0042641 actomyosin(GO:0042641)
0.1 0.9 GO:0031906 late endosome lumen(GO:0031906)
0.1 5.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 3.3 GO:0031201 SNARE complex(GO:0031201)
0.1 4.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 2.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 3.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.3 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 4.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 2.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 10.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.9 GO:0030426 growth cone(GO:0030426)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 12.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
2.1 8.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
1.6 4.9 GO:0050254 rhodopsin kinase activity(GO:0050254)
1.4 9.6 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.9 5.6 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.8 3.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.8 2.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.8 2.4 GO:0031403 lithium ion binding(GO:0031403)
0.7 4.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.7 9.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 1.9 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.6 2.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.5 3.5 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.5 4.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.5 2.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.4 5.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 6.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 2.8 GO:0050815 phosphoserine binding(GO:0050815)
0.3 3.0 GO:0032190 acrosin binding(GO:0032190)
0.3 0.9 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 2.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 0.9 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3 2.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 2.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.3 2.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 12.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 3.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 0.7 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 3.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 1.2 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.2 0.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 2.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 23.3 GO:0051087 chaperone binding(GO:0051087)
0.2 1.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 2.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 1.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2 1.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 3.0 GO:0097602 cullin family protein binding(GO:0097602)
0.2 7.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 5.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 12.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.2 2.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 0.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 3.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.7 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.9 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.1 GO:0070628 proteasome binding(GO:0070628)
0.1 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 7.7 GO:0019843 rRNA binding(GO:0019843)
0.1 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 3.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 3.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 6.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 6.4 GO:0004386 helicase activity(GO:0004386)
0.1 0.9 GO:0000150 recombinase activity(GO:0000150)
0.1 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 2.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 10.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 2.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 3.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.3 GO:0005262 calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 14.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 3.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 4.4 PID MYC PATHWAY C-MYC pathway
0.1 6.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 6.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 8.4 PID E2F PATHWAY E2F transcription factor network
0.1 5.2 PID AURORA B PATHWAY Aurora B signaling
0.1 3.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 4.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 18.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 8.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 5.9 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.3 2.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 13.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 5.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 5.7 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 5.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 16.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 6.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 12.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 8.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 8.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 2.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.2 REACTOME MEIOSIS Genes involved in Meiosis
0.1 1.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.6 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 13.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.9 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 1.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 3.2 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates